## Tue Oct 15 12:52:58 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/CMS1_bin.84.fa -m mmseqs --itype genome -o CMS1_bin.84 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/CMS1_bin.84 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS1_k127_1049267_3	1123504.JQKD01000048_gene1396	5.074e-158	522.0	COG0613@1|root,COG0613@2|Bacteria,1QYMM@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS1_k127_1049267_4	1231190.NA8A_19193	8.648e-150	498.0	COG0329@1|root,COG0329@2|Bacteria,1MWMN@1224|Proteobacteria,2TSAF@28211|Alphaproteobacteria,43JCG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	MA20_28770	-	-	-	-	-	-	-	-	-	-	-	DHDPS
CMS1_k127_1049267_5	1411123.JQNH01000001_gene3167	1.699e-134	448.0	COG0451@1|root,COG0451@2|Bacteria,1MWQ2@1224|Proteobacteria,2TTJ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	NAD dependent epimerase/dehydratase family	MA20_28780	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_1049267_7	365046.Rta_23730	7.062e-73	252.0	COG1309@1|root,COG1309@2|Bacteria,1R5AI@1224|Proteobacteria,2VH3Y@28216|Betaproteobacteria,4ABHB@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_9,TetR_N
CMS1_k127_1049267_6	2002.JOEQ01000021_gene6740	2.315e-106	364.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EJI6@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_1049267_13	2074.JNYD01000052_gene1548	0.0002091	52.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS1_k127_1049267_12	987059.RBXJA2T_00849	1.73e-08	62.0	2E92A@1|root,333BE@2|Bacteria,1N8BM@1224|Proteobacteria,2VW75@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1049267_0	1380390.JIAT01000012_gene3044	2.711e-234	741.0	COG0028@1|root,COG0028@2|Bacteria,2GKQM@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_1049267_9	479432.Sros_6173	4.4e-46	173.0	2DMP1@1|root,32SS8@2|Bacteria,2INWH@201174|Actinobacteria,4EM19@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
CMS1_k127_1049267_1	1230476.C207_06623	1.522e-202	638.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,3JTGN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	MA20_18685	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1049267_10	1120983.KB894573_gene123	9.905e-42	161.0	COG3090@1|root,COG3090@2|Bacteria,1NDFB@1224|Proteobacteria,2U1K8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	MA20_18680	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_1049267_2	543728.Vapar_3913	3.278e-163	521.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,4ABME@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_1049267_8	1122604.JONR01000045_gene2493	1.753e-64	229.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,1T055@1236|Gammaproteobacteria,1X6SQ@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1049267_11	1121015.N789_04330	9.997e-35	138.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_106658_5	1366050.N234_05180	5.614e-69	243.0	COG1024@1|root,COG1024@2|Bacteria,1P3FI@1224|Proteobacteria,2VHYZ@28216|Betaproteobacteria,1K1J3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG2	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_106658_3	1454004.AW11_02021	5.253e-100	335.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2VKTC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
CMS1_k127_106658_0	1097668.BYI23_C012260	2.919e-149	479.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2W1F0@28216|Betaproteobacteria,1K8H0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
CMS1_k127_106658_2	394221.Mmar10_1233	1.459e-102	342.0	COG0500@1|root,COG3000@1|root,COG2226@2|Bacteria,COG3000@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,43XEV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_106658_1	472759.Nhal_3006	1.039e-143	471.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,1SBT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent)	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
CMS1_k127_106658_11	1298593.TOL_0104	3.546e-12	79.0	2BJ0T@1|root,32D9D@2|Bacteria,1QSTS@1224|Proteobacteria,1SRUW@1236|Gammaproteobacteria,1XQ13@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_106658_6	1333856.L686_10820	6.742e-69	245.0	COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,1S4WF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS1_k127_106658_4	1123393.KB891316_gene1541	3.038e-86	288.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria	28216|Betaproteobacteria	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS1_k127_106658_8	243233.MCA1269	1.11e-43	162.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,1SANY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS1_k127_106658_9	1123228.AUIH01000039_gene2886	1.545e-31	130.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,1SATY@1236|Gammaproteobacteria,1XM06@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_106658_10	1121035.AUCH01000012_gene3009	2.073e-26	121.0	2EFF1@1|root,3397W@2|Bacteria,1N9PW@1224|Proteobacteria,2VX4Q@28216|Betaproteobacteria,2KXE8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_106658_7	420662.Mpe_A0677	1.371e-47	171.0	COG1028@1|root,COG1028@2|Bacteria,1QKCK@1224|Proteobacteria,2VN0G@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_1091676_48	1123228.AUIH01000006_gene2209	3.017e-05	46.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1XIBE@135619|Oceanospirillales	135619|Oceanospirillales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_1091676_35	1095769.CAHF01000001_gene3525	2.383e-70	251.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,473AX@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS1_k127_1091676_39	580332.Slit_0512	4.097e-68	240.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,44VRQ@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS1_k127_1091676_22	1288494.EBAPG3_9170	6.122e-115	374.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,371YE@32003|Nitrosomonadales	28216|Betaproteobacteria	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS1_k127_1091676_8	748247.AZKH_0536	5.169e-217	683.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,2KVA8@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
CMS1_k127_1091676_29	1380394.JADL01000001_gene2257	1.756e-87	298.0	COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2U4JI@28211|Alphaproteobacteria,2JUE6@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1091676_21	652103.Rpdx1_3839	3.867e-115	382.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,3JS4Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_19195	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_1091676_25	338969.Rfer_2342	7.691e-112	382.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VITJ@28216|Betaproteobacteria,4AA3T@80864|Comamonadaceae	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,sCache_2
CMS1_k127_1091676_5	1100721.ALKO01000018_gene1164	5.658e-242	777.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,4AAS9@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
CMS1_k127_1091676_40	1211115.ALIQ01000198_gene416	6.355e-65	226.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,3NB93@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K00256,ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_1091676_0	1123229.AUBC01000005_gene759	0.0	1435.0	COG1018@1|root,COG1600@1|root,COG1018@2|Bacteria,COG1600@2|Bacteria,1MU6E@1224|Proteobacteria,2TRE9@28211|Alphaproteobacteria,3JSXZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	vanB	-	-	ko:K03863	ko00627,ko01120,map00627,map01120	-	R05274	RC00392,RC01533	ko00000,ko00001	-	-	-	Dehalogenase,FAD_binding_6,Fer2,Fer4_16,Fer4_7,NAD_binding_1
CMS1_k127_1091676_10	644076.SCH4B_1483	1.445e-170	552.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,2TTVY@28211|Alphaproteobacteria,4NAYE@97050|Ruegeria	28211|Alphaproteobacteria	S	Flotillin	MA20_29840	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
CMS1_k127_1091676_4	935261.JAGL01000044_gene2097	3.621e-249	788.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,43NFB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.67	ko:K21802	ko00627,ko01120,map00627,map01120	-	R05699	RC00075	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_1091676_30	420324.KI911948_gene9289	2.557e-82	288.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSCA@28211|Alphaproteobacteria,1JZCQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	MA20_29505	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_1091676_26	1123228.AUIH01000031_gene1700	3.784e-106	350.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1XPF8@135619|Oceanospirillales	135619|Oceanospirillales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_1091676_23	314232.SKA53_00774	5.99e-113	387.0	COG4177@1|root,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_1091676_20	1123228.AUIH01000031_gene1698	1.253e-115	378.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,1XR8T@135619|Oceanospirillales	135619|Oceanospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_1091676_14	314262.MED193_18059	2.421e-143	467.0	COG0683@1|root,COG0683@2|Bacteria,1P7P3@1224|Proteobacteria,2UJ6G@28211|Alphaproteobacteria,2P3X1@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_1091676_7	1380394.JADL01000011_gene3804	8.195e-238	743.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPSC@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_1091676_3	596153.Alide_4206	9.369e-257	807.0	COG0365@1|root,COG0365@2|Bacteria,1MXDK@1224|Proteobacteria,2VIAE@28216|Betaproteobacteria,4ABQD@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_1091676_2	522306.CAP2UW1_1985	2.159e-287	895.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,1KPUE@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_1091676_17	748247.AZKH_p0193	1.124e-120	420.0	COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,2VPEA@28216|Betaproteobacteria,2KXIP@206389|Rhodocyclales	206389|Rhodocyclales	O	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
CMS1_k127_1091676_6	748247.AZKH_p0194	3.08e-241	763.0	COG0308@1|root,COG0308@2|Bacteria,1PVVK@1224|Proteobacteria,2VIU3@28216|Betaproteobacteria,2KY1X@206389|Rhodocyclales	206389|Rhodocyclales	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS1_k127_1091676_9	882378.RBRH_02396	8.52e-177	559.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,1K3VB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS1_k127_1091676_38	279714.FuraDRAFT_0405	1.091e-68	239.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,2KPV0@206351|Neisseriales	206351|Neisseriales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS1_k127_1091676_32	292415.Tbd_0388	7.284e-75	258.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,1KRND@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal L25p family	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS1_k127_1091676_11	1163617.SCD_n02621	4.648e-159	507.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_1091676_27	292415.Tbd_0386	5.891e-98	327.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,1KRYI@119069|Hydrogenophilales	119069|Hydrogenophilales	I	GHMP kinases N terminal domain	-	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_1091676_46	1123392.AQWL01000002_gene2119	4.523e-42	162.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria,1KS6V@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Outer membrane lipoprotein LolB	-	-	-	-	-	-	-	-	-	-	-	-	LolB
CMS1_k127_1091676_13	1163617.SCD_n02625	1.689e-150	495.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria	28216|Betaproteobacteria	H	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
CMS1_k127_1091676_28	497321.C664_16128	2.321e-94	316.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,2KVBM@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS1_k127_1091676_36	159450.NH14_06490	2.302e-69	238.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,1K08U@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_1091676_43	279714.FuraDRAFT_3860	1.332e-55	201.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,2KR30@206351|Neisseriales	206351|Neisseriales	L	RNA methyltransferase, RsmD family	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
CMS1_k127_1091676_16	76114.ebA1393	1.745e-123	404.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,2KVC3@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS1_k127_1091676_49	313589.JNB_06589	0.0002788	53.0	2EGGY@1|root,33A91@2|Bacteria	2|Bacteria	S	Pfam:DUF1602	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1091676_31	1123367.C666_07680	7.51e-77	270.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,2KUD0@206389|Rhodocyclales	206389|Rhodocyclales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
CMS1_k127_1091676_24	76114.ebA4241	1.586e-112	370.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,2KUT2@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
CMS1_k127_1091676_33	1175306.GWL_35690	2.572e-71	247.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,473BA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Involved in biogenesis of respiratory and photosynthetic systems	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_1091676_18	1000565.METUNv1_02097	1.123e-117	396.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,2KVHR@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS1_k127_1091676_44	1000565.METUNv1_02095	8.477e-48	180.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria,2KWU1@206389|Rhodocyclales	206389|Rhodocyclales	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1091676_45	1266925.JHVX01000016_gene193	3.373e-44	170.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,372Z1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
CMS1_k127_1091676_47	1000565.METUNv1_02093	5.23e-16	87.0	2A8MT@1|root,30XQ7@2|Bacteria,1PJJK@1224|Proteobacteria,2WB51@28216|Betaproteobacteria,2KXIZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
CMS1_k127_1091676_19	1000565.METUNv1_02092	2.815e-116	381.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,2KVIW@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS1_k127_1091676_37	497321.C664_18197	2.331e-69	241.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria,2KWGM@206389|Rhodocyclales	206389|Rhodocyclales	O	oxidase assembly	-	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
CMS1_k127_1091676_1	1000565.METUNv1_02089	1.207e-290	899.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,2KUWI@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_1091676_12	62928.azo3304	1.635e-156	503.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,2KV6W@206389|Rhodocyclales	206389|Rhodocyclales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
CMS1_k127_1091676_34	76114.ebA1067	1.42e-70	248.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KUJH@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS1_k127_1091676_15	123899.JPQP01000003_gene1342	3.503e-136	448.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VJN4@28216|Betaproteobacteria,3T30K@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_1091676_42	1454004.AW11_00151	1.494e-56	222.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,1KQYC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS1_k127_1091676_41	292415.Tbd_2407	2.282e-62	220.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,1KSH2@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_109334_12	795666.MW7_0843	0.0004605	44.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1JZM8@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_109334_5	358220.C380_09455	4.041e-104	344.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4ACE3@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	tsaC	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_109334_4	1175306.GWL_13330	7.962e-135	441.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,473E2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CMS1_k127_109334_8	1304883.KI912532_gene2957	2.3e-57	201.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KWKR@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS1_k127_109334_10	1095769.CAHF01000011_gene2600	1.977e-50	184.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,472P7@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Small MutS-related domain	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS1_k127_109334_2	85643.Tmz1t_1762	2.403e-166	528.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,2KUD7@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_109334_7	159087.Daro_1294	3.886e-74	256.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria,2KVQ8@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_109334_0	580332.Slit_2580	3.555e-309	964.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,44VA1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_109334_9	1000565.METUNv1_02871	5.777e-54	212.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,2KWH0@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
CMS1_k127_109334_1	1454004.AW11_01089	2.525e-207	654.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,1KPPA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	DNA replication, recombination, and repair	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS1_k127_109334_3	395493.BegalDRAFT_2197	1.798e-160	516.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,45ZPQ@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS1_k127_109334_6	330214.NIDE3221	2.056e-74	265.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_109334_11	194867.ALBQ01000011_gene384	0.0002986	49.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CMS1_k127_1115399_8	596154.Alide2_0526	3.889e-111	365.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4A9MZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_1115399_4	1205680.CAKO01000040_gene670	4.498e-208	661.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2TRZ0@28211|Alphaproteobacteria,2JPX8@204441|Rhodospirillales	204441|Rhodospirillales	E	homoserine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,NAD_binding_3,SAF
CMS1_k127_1115399_15	1502770.JQMG01000001_gene1647	2.516e-30	125.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,2KN3C@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
CMS1_k127_1115399_3	640081.Dsui_2317	4.892e-225	702.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,2KUEC@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_1115399_7	1163617.SCD_n01611	1.118e-140	450.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS1_k127_1115399_2	640081.Dsui_2313	1.32e-277	867.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,2KVHT@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS1_k127_1115399_11	56780.SYN_00196	1.045e-40	160.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,42XQK@68525|delta/epsilon subdivisions,2WSNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS1_k127_1115399_0	1123354.AUDR01000015_gene324	2.264e-295	922.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,1KSEC@119069|Hydrogenophilales	1224|Proteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1,6.2.1.16	ko:K01895,ko:K01907	ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354,R01357	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_1115399_13	159087.Daro_1937	6.022e-37	145.0	COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,2WEH8@28216|Betaproteobacteria,2KWT4@206389|Rhodocyclales	206389|Rhodocyclales	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS1_k127_1115399_1	1095769.CAHF01000011_gene2486	4.403e-282	883.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,472V4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etf	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	DAO,ETF_QO,FAD_binding_2,NAD_binding_8
CMS1_k127_1115399_12	688245.CtCNB1_3252	1.222e-40	157.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,2VTYA@28216|Betaproteobacteria,4AEEH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
CMS1_k127_1115399_14	1283300.ATXB01000001_gene163	4.643e-36	148.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XDMM@135618|Methylococcales	135618|Methylococcales	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
CMS1_k127_1115399_10	1192124.LIG30_3922	1.187e-46	183.0	COG0583@1|root,COG0583@2|Bacteria,1P2I1@1224|Proteobacteria,2VR8C@28216|Betaproteobacteria,1KGG0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1115399_9	1231392.OCGS_0273	9.412e-81	281.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TRHD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_1115399_16	1231392.OCGS_0275	2.764e-20	97.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
CMS1_k127_1115399_6	1417296.U879_08365	3.705e-141	464.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1115399_5	1123504.JQKD01000011_gene2361	2.012e-179	574.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2WEXA@28216|Betaproteobacteria,4A9KB@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS1_k127_1115399_18	47763.JNZA01000017_gene1449	0.0002259	53.0	COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_1115399_17	29581.BW37_05381	3.681e-18	85.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,47368@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS1_k127_1119594_4	626418.bglu_1g11010	7.549e-94	312.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2VIKG@28216|Betaproteobacteria,1K411@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Fad dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_1119594_3	1207063.P24_07559	6.986e-102	342.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,2TT88@28211|Alphaproteobacteria,2JQ2A@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_1119594_9	397945.Aave_3298	1.176e-46	175.0	COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria	1224|Proteobacteria	G	transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_1119594_0	266264.Rmet_1876	2.028e-166	544.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VJME@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1119594_6	1499967.BAYZ01000190_gene3821	4.048e-68	239.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	ydjZ	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_1119594_1	1304883.KI912532_gene2562	4.556e-151	492.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,2KU9G@206389|Rhodocyclales	206389|Rhodocyclales	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
CMS1_k127_1119594_2	1230476.C207_06485	1.492e-117	385.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2TSK5@28211|Alphaproteobacteria,3JS6T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_1119594_7	84531.JMTZ01000168_gene741	3.672e-53	196.0	COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,1S9MZ@1236|Gammaproteobacteria,1X6ZP@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
CMS1_k127_1119594_8	1038859.AXAU01000011_gene2398	2.527e-47	179.0	2CGAW@1|root,344FT@2|Bacteria,1RGC6@1224|Proteobacteria,2U873@28211|Alphaproteobacteria,3JZ52@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_1119594_5	1333998.M2A_1262	3.213e-83	283.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,4BSEJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_1119594_10	224911.27352622	0.0002477	48.0	COG3686@1|root,COG3686@2|Bacteria,1RAEH@1224|Proteobacteria,2U5JJ@28211|Alphaproteobacteria,3JY5A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MAPEG family	MA20_30600	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_1129110_7	1235457.C404_13920	1.293e-53	191.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS1_k127_1129110_2	497321.C664_06323	2.102e-155	501.0	COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,2VPET@28216|Betaproteobacteria,2M01E@206389|Rhodocyclales	206389|Rhodocyclales	Q	Benzoate membrane transport protein	-	-	-	ko:K05782	-	-	-	-	ko00000,ko02000	2.A.46.1	-	-	BenE
CMS1_k127_1129110_6	472175.EL18_02204	2.453e-104	347.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,43NEF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_1129110_0	314231.FP2506_14289	6.179e-213	672.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2PKB4@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA,TctB
CMS1_k127_1129110_8	1121939.L861_14180	1.22e-13	77.0	2DN72@1|root,32VWT@2|Bacteria,1R35M@1224|Proteobacteria,1SV0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
CMS1_k127_1129110_3	543728.Vapar_5519	1.654e-153	498.0	COG4948@1|root,COG4948@2|Bacteria,1MW3F@1224|Proteobacteria,2VP7A@28216|Betaproteobacteria,4AF3H@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1129110_4	292415.Tbd_2815	2.37e-150	490.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KS5H@119069|Hydrogenophilales	119069|Hydrogenophilales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS1_k127_1129110_1	378806.STAUR_4691	1.456e-171	567.0	COG2518@1|root,COG2518@2|Bacteria,1QX9V@1224|Proteobacteria,42Z9X@68525|delta/epsilon subdivisions,2WUEX@28221|Deltaproteobacteria,2YX7N@29|Myxococcales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1129110_5	331869.BAL199_07223	3.133e-134	440.0	COG0715@1|root,COG0715@2|Bacteria,1NF3S@1224|Proteobacteria,2TREQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	MA20_40210	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_1136204_3	1454004.AW11_03340	2.284e-143	456.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,1KQK5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_1136204_8	395019.Bmul_2202	1.495e-69	241.0	COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,2VJCF@28216|Betaproteobacteria,1K1I9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
CMS1_k127_1136204_11	640081.Dsui_1522	3.351e-49	202.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS1_k127_1136204_6	159087.Daro_2112	1.39e-100	355.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,2KW7J@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS1_k127_1136204_7	640081.Dsui_3393	4.088e-77	280.0	COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,2VKV2@28216|Betaproteobacteria,2KWJB@206389|Rhodocyclales	206389|Rhodocyclales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_1136204_4	640081.Dsui_3392	5.122e-129	424.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2VK27@28216|Betaproteobacteria,2KVTN@206389|Rhodocyclales	206389|Rhodocyclales	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
CMS1_k127_1136204_12	1454004.AW11_02848	2.911e-45	184.0	COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria	1224|Proteobacteria	P	COG1863 Multisubunit Na H antiporter MnhE subunit	mnhE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
CMS1_k127_1136204_15	1454004.AW11_02849	5.643e-32	126.0	COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria	1224|Proteobacteria	P	Multiple resistance and pH regulation protein F	mnhF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
CMS1_k127_1136204_14	1454004.AW11_02850	4.571e-32	139.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	mnhG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
CMS1_k127_1136204_9	1454004.AW11_02851	1.043e-63	229.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria	1224|Proteobacteria	P	Na H antiporter, MnhB	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
CMS1_k127_1136204_10	1454004.AW11_02852	1.553e-55	207.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria	1224|Proteobacteria	P	Na H antiporter, MnhB	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
CMS1_k127_1136204_13	1454004.AW11_02853	1.261e-41	162.0	COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria	1224|Proteobacteria	P	COG1006 Multisubunit Na H antiporter, MnhC subunit	mnhC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
CMS1_k127_1136204_2	1454004.AW11_02854	3.156e-186	601.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2VP1W@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
CMS1_k127_1136204_1	1454004.AW11_02855	6.876e-213	672.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2VPQP@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
CMS1_k127_1136204_16	631454.N177_3896	7.631e-23	114.0	2EDYZ@1|root,337TS@2|Bacteria,1N7SA@1224|Proteobacteria,2UNBF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1136204_0	1454004.AW11_02857	3.618e-241	757.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria	1224|Proteobacteria	CP	formate hydrogenlyase subunit 3 multisubunit Na H antiporter, MnhD subunit	nuoL3	-	-	ko:K05568,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
CMS1_k127_1136204_5	1126627.BAWE01000004_gene4069	1.162e-113	373.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria,3JWB9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
CMS1_k127_116947_36	1123393.KB891317_gene2266	7.326e-67	235.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,1KSTM@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp33 protein	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS1_k127_116947_72	84531.JMTZ01000046_gene1062	2.105e-07	62.0	2EJ4R@1|root,33CVZ@2|Bacteria,1P1AA@1224|Proteobacteria,1T8MR@1236|Gammaproteobacteria,1XAY9@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_116947_71	1121127.JAFA01000020_gene506	2.732e-08	60.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2VZ7K@28216|Betaproteobacteria,1K6BR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_116947_70	864051.BurJ1DRAFT_3296	6.988e-11	67.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria	1224|Proteobacteria	S	Beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_116947_56	1408444.JHYC01000035_gene1499	1.574e-39	155.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,1S9I3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nuclease	Z012_04225	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
CMS1_k127_116947_64	1121875.KB907547_gene3035	9.428e-19	94.0	2EM9G@1|root,33EYK@2|Bacteria,4P33X@976|Bacteroidetes,1I90G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_116947_58	404380.Gbem_1696	3.042e-38	152.0	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_116947_69	338966.Ppro_0858	6.988e-14	75.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
CMS1_k127_116947_54	1265505.ATUG01000001_gene4392	1.763e-41	159.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
CMS1_k127_116947_66	1231190.NA8A_10738	2.741e-18	86.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria,43QQ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_116947_32	243365.CV_1741	2.413e-72	249.0	COG0500@1|root,COG0500@2|Bacteria,1RFR0@1224|Proteobacteria,2VRPA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_116947_61	1395571.TMS3_0114755	2.747e-31	128.0	COG3278@1|root,COG3278@2|Bacteria,1N9ZN@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_116947_52	452637.Oter_3105	2.491e-47	176.0	COG2020@1|root,COG2020@2|Bacteria,46WMG@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_116947_21	1244869.H261_06494	1.557e-100	332.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,2JZBE@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_116947_24	1205680.CAKO01000002_gene3004	3.083e-92	312.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,2JS5W@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_116947_13	1121033.AUCF01000030_gene167	8.428e-118	401.0	COG4177@1|root,COG4177@2|Bacteria,1NE3E@1224|Proteobacteria,2TTWY@28211|Alphaproteobacteria,2JT5A@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_116947_15	1121033.AUCF01000030_gene168	1.422e-108	359.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2TSH5@28211|Alphaproteobacteria,2JSG0@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_116947_10	1121033.AUCF01000030_gene174	1.851e-133	440.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U16N@28211|Alphaproteobacteria,2JVNK@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_116947_62	264198.Reut_A0565	3.708e-28	119.0	COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2VTDX@28216|Betaproteobacteria,1K4KI@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_116947_4	1121033.AUCF01000016_gene5480	1.67e-221	706.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,2JPYI@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme	-	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
CMS1_k127_116947_11	1121033.AUCF01000016_gene5484	9.461e-128	418.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,2JU12@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_116947_3	1244869.H261_12086	1.251e-231	736.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2JPNR@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_116947_19	1144319.PMI16_04672	1.217e-102	355.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,473MY@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	methyl-accepting chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
CMS1_k127_116947_65	1123255.JHYS01000014_gene578	9.48e-19	88.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2VYZ6@28216|Betaproteobacteria,4AG1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_116947_55	991905.SL003B_2822	2.883e-41	158.0	COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,2U95F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_116947_47	987059.RBXJA2T_04898	3.349e-56	207.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VPEY@28216|Betaproteobacteria,1KPA9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	LysE type translocator	leuE_1	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_116947_31	292415.Tbd_0519	1.24e-72	255.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS1_k127_116947_45	1207063.P24_07111	3.786e-59	206.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2JSMY@204441|Rhodospirillales	204441|Rhodospirillales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
CMS1_k127_116947_68	887898.HMPREF0551_1181	3.252e-16	89.0	COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria,1K4ZB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	(Lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
CMS1_k127_116947_25	314278.NB231_06246	7.887e-87	309.0	COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1X0PY@135613|Chromatiales	135613|Chromatiales	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS1_k127_116947_20	743299.Acife_1342	3.943e-101	345.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,2NCYJ@225057|Acidithiobacillales	225057|Acidithiobacillales	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
CMS1_k127_116947_50	1265502.KB905997_gene3341	5.524e-51	186.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,4ADEE@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS1_k127_116947_51	1123487.KB892835_gene3414	9.125e-48	185.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,2KW81@206389|Rhodocyclales	206389|Rhodocyclales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS1_k127_116947_18	261292.Nit79A3_0926	5.388e-104	364.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,371T6@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	ko:K03406,ko:K03776,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH
CMS1_k127_116947_1	748247.AZKH_2438	0.0	1021.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,2KV02@206389|Rhodocyclales	206389|Rhodocyclales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_116947_42	1163409.UUA_04623	2.397e-62	222.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,1T095@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_116947_16	748247.AZKH_2820	2.898e-107	353.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KVHM@206389|Rhodocyclales	206389|Rhodocyclales	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_116947_41	76114.ebA6408	1.332e-62	223.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,2KW30@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_116947_22	1121035.AUCH01000013_gene3074	9.076e-97	322.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,2KVCE@206389|Rhodocyclales	206389|Rhodocyclales	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
CMS1_k127_116947_38	1454004.AW11_00667	1.717e-64	224.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,1KQMC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Rrf2 family transcriptional regulator, iron-sulfur cluster assembly	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
CMS1_k127_116947_5	93220.LV28_23380	1.629e-214	674.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,1K14U@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS1_k127_116947_35	748658.KB907314_gene146	1.621e-67	231.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1WW3I@135613|Chromatiales	135613|Chromatiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS1_k127_116947_49	1304883.KI912532_gene2399	4.973e-53	188.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,2KWP9@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS1_k127_116947_48	580332.Slit_2252	2.124e-54	196.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,44VVM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
CMS1_k127_116947_2	1387312.BAUS01000011_gene1919	1.977e-253	801.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,2KKJA@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CMS1_k127_116947_53	1000565.METUNv1_00567	8.925e-47	171.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,2KWP0@206389|Rhodocyclales	206389|Rhodocyclales	C	Ferredoxin, 2Fe-2S type, ISC system	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS1_k127_116947_63	292415.Tbd_1170	2.958e-26	110.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,1KTDJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Iron-sulphur cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
CMS1_k127_116947_8	1380394.JADL01000007_gene4673	6.91e-156	502.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	28211|Alphaproteobacteria	C	III protein, CoA-transferase family	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_116947_28	666684.AfiDRAFT_3816	1.03e-76	270.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,3JRS0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.1.1.41,4.2.1.17	ko:K01692,ko:K11264	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_116947_33	1121943.KB899991_gene2417	2.946e-72	261.0	COG4122@1|root,COG4122@2|Bacteria,1N57D@1224|Proteobacteria,1S6JT@1236|Gammaproteobacteria,1XK1C@135619|Oceanospirillales	135619|Oceanospirillales	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
CMS1_k127_116947_57	765912.Thimo_1678	9.102e-39	152.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1WYGS@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS1_k127_116947_0	926554.KI912640_gene1362	0.0	1121.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1WI44@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS1_k127_116947_17	1056512.D515_01312	1.678e-106	388.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XSK0@135623|Vibrionales	135623|Vibrionales	H	COG0404 Glycine cleavage system T protein (aminomethyltransferase)	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_116947_6	1121015.N789_08805	3.356e-172	562.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1X9KC@135614|Xanthomonadales	135614|Xanthomonadales	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
CMS1_k127_116947_26	314345.SPV1_11301	2.119e-79	270.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria	1224|Proteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_116947_59	521045.Kole_0199	1.255e-36	146.0	COG2110@1|root,COG2110@2|Bacteria,2GD2K@200918|Thermotogae	200918|Thermotogae	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS1_k127_116947_30	497321.C664_00765	5.159e-75	267.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,2KVE7@206389|Rhodocyclales	206389|Rhodocyclales	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
CMS1_k127_116947_67	292415.Tbd_1531	5.073e-18	98.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2VVNP@28216|Betaproteobacteria,1KRVA@119069|Hydrogenophilales	119069|Hydrogenophilales	T	BolA-like protein	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
CMS1_k127_116947_34	522306.CAP2UW1_3308	3.521e-72	247.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,1KQ28@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
CMS1_k127_116947_44	243231.GSU3361	1.236e-59	230.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,43TZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_116947_43	1266925.JHVX01000006_gene2133	2.895e-60	212.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,373GQ@32003|Nitrosomonadales	28216|Betaproteobacteria	C	SelR domain	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS1_k127_116947_40	1381123.AYOD01000005_gene1210	7.356e-63	218.0	COG2128@1|root,COG2128@2|Bacteria,1RD2I@1224|Proteobacteria,2U7MW@28211|Alphaproteobacteria,43KM1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_116947_29	998674.ATTE01000001_gene1554	6.401e-76	261.0	COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,1S0F8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cysteine dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
CMS1_k127_116947_60	1156919.QWC_05829	5.181e-33	133.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_116947_9	1123257.AUFV01000005_gene1292	1.453e-145	472.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria,1X6Z0@135614|Xanthomonadales	135614|Xanthomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS1_k127_116947_12	670292.JH26_24625	4.783e-120	400.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,1JT1V@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_116947_7	477184.KYC_27262	9.313e-160	511.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJJD@28216|Betaproteobacteria,3T343@506|Alcaligenaceae	28216|Betaproteobacteria	C	carnitine dehydratase	frc_10	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_116947_46	365046.Rta_01670	8.859e-57	211.0	COG0697@1|root,COG0697@2|Bacteria,1MY34@1224|Proteobacteria,2VJYT@28216|Betaproteobacteria,4A9ZH@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_116947_23	1231391.AMZF01000110_gene918	9.902e-97	325.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2VZJ0@28216|Betaproteobacteria,3T6AW@506|Alcaligenaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_116947_14	285535.JOEY01000038_gene2798	2.25e-109	361.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
CMS1_k127_116947_39	1337936.IJ00_26380	3.863e-64	235.0	COG0119@1|root,COG0119@2|Bacteria,1G3A7@1117|Cyanobacteria,1HMGZ@1161|Nostocales	1117|Cyanobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_116947_27	1394178.AWOO02000014_gene7675	7.225e-79	271.0	COG1028@1|root,COG1028@2|Bacteria,2IAGY@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_116947_37	388399.SSE37_01035	1.715e-65	240.0	COG1638@1|root,COG1638@2|Bacteria,1MW3I@1224|Proteobacteria,2TTF8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_1184673_7	748247.AZKH_4267	1.222e-150	482.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VMHS@28216|Betaproteobacteria,2KUQ2@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_1184673_2	748247.AZKH_4266	7.368e-235	744.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,2KU6T@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_1184673_23	85643.Tmz1t_0650	3.899e-40	152.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Thioesterase superfamily protein	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
CMS1_k127_1184673_17	1278073.MYSTI_07504	2.037e-75	271.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,435IS@68525|delta/epsilon subdivisions,2WZWF@28221|Deltaproteobacteria,2Z0UC@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_1184673_27	1223521.BBJX01000006_gene1794	1.201e-14	85.0	COG3713@1|root,COG3713@2|Bacteria,1PUKH@1224|Proteobacteria,2WAUU@28216|Betaproteobacteria,4AHGK@80864|Comamonadaceae	28216|Betaproteobacteria	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
CMS1_k127_1184673_22	414684.RC1_3303	2.967e-47	177.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U7TT@28211|Alphaproteobacteria,2JWI6@204441|Rhodospirillales	204441|Rhodospirillales	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS1_k127_1184673_19	1095769.CAHF01000011_gene2277	6.57e-64	235.0	COG0625@1|root,COG0625@2|Bacteria,1RAP2@1224|Proteobacteria,2VQGV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
CMS1_k127_1184673_12	365046.Rta_23870	1.505e-91	310.0	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,2VP8F@28216|Betaproteobacteria,4AD6N@80864|Comamonadaceae	28216|Betaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1184673_4	1122604.JONR01000036_gene3805	2.753e-197	621.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,1X4KZ@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1184673_5	1122604.JONR01000036_gene3804	6.696e-165	524.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,1X3BR@135614|Xanthomonadales	135614|Xanthomonadales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_1184673_20	580332.Slit_1775	6.286e-56	200.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria	28216|Betaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS1_k127_1184673_29	1095769.CAHF01000011_gene2412	2.3e-12	71.0	COG5481@1|root,COG5481@2|Bacteria,1R3J0@1224|Proteobacteria,2WIIA@28216|Betaproteobacteria,47855@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
CMS1_k127_1184673_18	1121374.KB891576_gene724	1.673e-74	265.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1184673_14	1380394.JADL01000003_gene5080	1.256e-87	302.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,2JRVV@204441|Rhodospirillales	204441|Rhodospirillales	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_1184673_13	381666.H16_A2371	3.145e-88	304.0	COG3568@1|root,COG3568@2|Bacteria,1R9NP@1224|Proteobacteria,2WGEU@28216|Betaproteobacteria,1K0J8@119060|Burkholderiaceae	28216|Betaproteobacteria	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_1184673_25	211165.AJLN01000096_gene5024	4.576e-35	143.0	COG4446@1|root,COG4446@2|Bacteria,1G6W2@1117|Cyanobacteria,1JKYA@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS1_k127_1184673_10	221288.JH992901_gene1226	1.467e-132	433.0	COG1171@1|root,COG1171@2|Bacteria,1G22X@1117|Cyanobacteria,1JHYB@1189|Stigonemataceae	1117|Cyanobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_1184673_30	1121272.KB903283_gene5154	4.015e-08	64.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.41	ko:K00559	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00102	R04427,R07481	RC00003,RC01154	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF938,Methyltransf_11
CMS1_k127_1184673_31	1206732.BAGD01000074_gene3036	0.0001482	51.0	COG0183@1|root,COG1024@1|root,COG0183@2|Bacteria,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4FU2F@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	2.3.1.9,4.2.1.149	ko:K00626,ko:K08299	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177,R10675	RC00004,RC00326,RC01095	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ECH_1,Polyketide_cyc2
CMS1_k127_1184673_8	1131553.JIBI01000046_gene1600	3.683e-145	479.0	COG2855@1|root,COG2855@2|Bacteria	2|Bacteria	P	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
CMS1_k127_1184673_11	1385517.N800_06175	4.144e-129	428.0	COG0515@1|root,COG0589@1|root,COG0515@2|Bacteria,COG0589@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Serine Threonine protein	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
CMS1_k127_1184673_16	290397.Adeh_3700	1.334e-77	270.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42RNB@68525|delta/epsilon subdivisions,2WNEW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_1184673_0	1380394.JADL01000003_gene4767	2.498e-266	830.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JUXN@204441|Rhodospirillales	204441|Rhodospirillales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_1184673_3	991905.SL003B_2672	3.06e-206	652.0	COG0742@1|root,COG0742@2|Bacteria,1MW6A@1224|Proteobacteria,2TQNI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ribosomal rna small subunit methyltransferase	MA20_07810	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1184673_21	935840.JAEQ01000003_gene278	9.344e-48	186.0	COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria,43KAG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	COG0685 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_1184673_15	1122603.ATVI01000001_gene1847	3.682e-80	276.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XCPJ@135614|Xanthomonadales	135614|Xanthomonadales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1184673_9	365046.Rta_32510	3.915e-137	449.0	COG1638@1|root,COG1638@2|Bacteria,1NTFS@1224|Proteobacteria,2VM5I@28216|Betaproteobacteria,4AGQZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_1184673_24	1380394.JADL01000004_gene6057	3.316e-35	140.0	COG3090@1|root,COG3090@2|Bacteria,1RA8Q@1224|Proteobacteria,2U67A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TRAP-type C4-dicarboxylate transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_1184673_6	365046.Rta_32490	1.665e-159	513.0	COG4664@1|root,COG4664@2|Bacteria,1QU8F@1224|Proteobacteria,2VKVK@28216|Betaproteobacteria,4AGQC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1184673_1	748247.AZKH_1887	3.282e-266	831.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,2KXVQ@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_1194766_15	595537.Varpa_4750	1.133e-84	298.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,4ACFV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
CMS1_k127_1194766_12	93220.LV28_07060	1.211e-126	429.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VJMJ@28216|Betaproteobacteria,1K058@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_1194766_7	1192868.CAIU01000013_gene1747	2.927e-148	479.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,43HHC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	ABC transporter	hndI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_1194766_21	748247.AZKH_1810	1.741e-09	63.0	2ERQA@1|root,33J9N@2|Bacteria,1NI0Z@1224|Proteobacteria,2VYZY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1194766_11	1095769.CAHF01000006_gene1955	7.245e-130	432.0	COG0312@1|root,COG0312@2|Bacteria,1QM7I@1224|Proteobacteria,2VNXI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS1_k127_1194766_18	404589.Anae109_0599	1.176e-52	202.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase	pgl	-	2.7.1.12,3.1.1.31	ko:K00851,ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R01737,R02035	RC00002,RC00017,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CMS1_k127_1194766_4	1234364.AMSF01000033_gene402	3.27e-173	556.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RQE4@1236|Gammaproteobacteria,1X59Z@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS1_k127_1194766_10	404589.Anae109_0596	5.985e-142	459.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	6-phosphogluconate dehydrogenase (decarboxylating)	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2620	6PGD,NAD_binding_2
CMS1_k127_1194766_5	748247.AZKH_p0306	6.965e-156	499.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria,2KXTK@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_1194766_8	335543.Sfum_2392	1.385e-146	474.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MQ5A@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS1_k127_1194766_1	1123393.KB891332_gene2689	1.171e-231	750.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2WGGY@28216|Betaproteobacteria,1KSCB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_1194766_13	1454004.AW11_02751	1.194e-114	381.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2VH7G@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993,ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_1194766_20	1331060.RLDS_00835	7.674e-31	123.0	COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,2UFMJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1194766_3	1095769.CAHF01000006_gene1954	1.532e-173	556.0	COG0312@1|root,COG0312@2|Bacteria,1NSH6@1224|Proteobacteria,2VJRT@28216|Betaproteobacteria,475XU@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS1_k127_1194766_17	497321.C664_04507	5.422e-70	242.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2VQJW@28216|Betaproteobacteria,2KWEH@206389|Rhodocyclales	206389|Rhodocyclales	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS1_k127_1194766_19	1121939.L861_20355	6.271e-50	181.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria,1XKQJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_1194766_16	1538295.JY96_06070	7.831e-79	282.0	COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,2VNFR@28216|Betaproteobacteria,1KNBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
CMS1_k127_1194766_14	614083.AWQR01000020_gene172	3.672e-107	352.0	COG1994@1|root,COG1994@2|Bacteria,1PM1Q@1224|Proteobacteria,2VM3E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1194766_9	760117.JN27_13275	3.558e-144	463.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VHCB@28216|Betaproteobacteria,473CI@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NADPH quinone oxidoreductase	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1194766_6	1265502.KB905930_gene1445	3.336e-149	481.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2VIAN@28216|Betaproteobacteria,4AC8Z@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	abmD	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1194766_2	1532557.JL37_14150	1.573e-216	684.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,3T2M2@506|Alcaligenaceae	28216|Betaproteobacteria	I	2-aminobenzoate-CoA ligase	bclA_1	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1194766_0	1411123.JQNH01000001_gene266	0.0	1037.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
CMS1_k127_1201186_13	420324.KI912045_gene4419	2.781e-70	242.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,1JTF7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	MA20_20705	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_1201186_22	335283.Neut_0445	1.216e-29	124.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,373G4@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS1_k127_1201186_18	292415.Tbd_2374	7.658e-42	160.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,1KRS5@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RimM N-terminal domain	-	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS1_k127_1201186_9	748247.AZKH_3485	2.005e-99	332.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,2KUD3@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS1_k127_1201186_14	1000565.METUNv1_02493	2.828e-55	198.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,2KWCD@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS1_k127_1201186_4	1266925.JHVX01000008_gene358	1.904e-142	462.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,371M0@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS1_k127_1201186_17	292415.Tbd_2191	5.925e-46	169.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,1KSAY@119069|Hydrogenophilales	119069|Hydrogenophilales	H	6,7-dimethyl-8-ribityllumazine synthase	-	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS1_k127_1201186_19	983917.RGE_39080	3.199e-36	151.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,1KKV8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS1_k127_1201186_8	1123393.KB891316_gene1504	2.199e-106	353.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,1KRKQ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	AIR synthase related protein, N-terminal domain	-	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_1201186_15	1288494.EBAPG3_7830	2.348e-49	190.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,3734R@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CMS1_k127_1201186_16	76114.ebA3399	1.286e-47	187.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,2KWIK@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
CMS1_k127_1201186_5	1123393.KB891333_gene2646	2.037e-139	457.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
CMS1_k127_1201186_1	1123393.KB891333_gene2645	9.916e-184	580.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,2WFUM@28216|Betaproteobacteria,1KTIG@119069|Hydrogenophilales	119069|Hydrogenophilales	O	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_1201186_7	335543.Sfum_3501	1.134e-109	383.0	COG2271@1|root,COG2271@2|Bacteria,1QXP5@1224|Proteobacteria,43C51@68525|delta/epsilon subdivisions,2X7FD@28221|Deltaproteobacteria,2MR8I@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_1201186_3	1123257.AUFV01000015_gene3552	2.591e-149	494.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria,1X9M9@135614|Xanthomonadales	135614|Xanthomonadales	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
CMS1_k127_1201186_0	864051.BurJ1DRAFT_0984	5.681e-237	741.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,1KKFD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	polyphosphate kinase	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS1_k127_1201186_20	1288494.EBAPG3_5330	1.09e-32	145.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,37363@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS1_k127_1201186_11	1163617.SCD_n02381	2.107e-93	327.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
CMS1_k127_1201186_6	1528106.JRJE01000004_gene631	9.787e-135	434.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2JQIB@204441|Rhodospirillales	204441|Rhodospirillales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_1201186_2	1163617.SCD_n00848	1.441e-171	546.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_1201186_21	395495.Lcho_0496	6.986e-32	130.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,1KMD0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS1_k127_1201186_23	1278309.KB907105_gene1385	4.379e-28	120.0	2BZMS@1|root,32Z9B@2|Bacteria,1NCFD@1224|Proteobacteria,1SPFN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
CMS1_k127_1201186_10	1386089.N865_11555	1.873e-97	365.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
CMS1_k127_1201186_24	1123261.AXDW01000011_gene504	1.484e-18	104.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,1X9HN@135614|Xanthomonadales	135614|Xanthomonadales	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA
CMS1_k127_1201186_12	1298867.AUES01000042_gene3563	3.987e-73	284.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS1_k127_124994_5	1380387.JADM01000003_gene2465	4.288e-145	483.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XKXU@135619|Oceanospirillales	135619|Oceanospirillales	M	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_124994_8	1121033.AUCF01000001_gene2030	3.844e-77	269.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_124994_0	882378.RBRH_02469	0.0	1419.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,1K1A9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS1_k127_124994_13	1043205.AFYF01000087_gene1181	1.217e-13	83.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4FFAM@85021|Intrasporangiaceae	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
CMS1_k127_124994_12	580332.Slit_2776	6.182e-24	105.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS1_k127_124994_6	1123368.AUIS01000021_gene987	3.881e-140	452.0	COG0725@1|root,COG0725@2|Bacteria,1NACV@1224|Proteobacteria,1T2QW@1236|Gammaproteobacteria,2ND9P@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
CMS1_k127_124994_11	1158292.JPOE01000005_gene745	6.002e-32	130.0	COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,2VTZ3@28216|Betaproteobacteria,1KMNA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
CMS1_k127_124994_1	1249627.D779_3681	4.189e-241	763.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,1RM9Q@1236|Gammaproteobacteria,1WW1W@135613|Chromatiales	135613|Chromatiales	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
CMS1_k127_124994_7	857087.Metme_1585	2.248e-125	423.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,1RPCY@1236|Gammaproteobacteria,1XE7T@135618|Methylococcales	135618|Methylococcales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
CMS1_k127_124994_9	395493.BegalDRAFT_0661	2.811e-73	254.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,1RRYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	hydrogenase 4 membrane	hyfE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q2
CMS1_k127_124994_2	1121918.ARWE01000001_gene404	6.991e-225	718.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
CMS1_k127_124994_4	1283300.ATXB01000001_gene1582	2.232e-188	628.0	COG0852@1|root,COG3261@1|root,COG0852@2|Bacteria,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,1RSJ4@1236|Gammaproteobacteria,1XERA@135618|Methylococcales	135618|Methylococcales	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
CMS1_k127_124994_10	243233.MCA1137	3.2e-71	244.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,1RNUG@1236|Gammaproteobacteria,1XEI8@135618|Methylococcales	135618|Methylococcales	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
CMS1_k127_124994_3	1123504.JQKD01000019_gene5539	3.101e-191	617.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,2VH0U@28216|Betaproteobacteria,4AAMR@80864|Comamonadaceae	28216|Betaproteobacteria	J	Translation elongation factor	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
CMS1_k127_125316_8	279714.FuraDRAFT_2222	1.253e-36	142.0	COG0640@1|root,COG0640@2|Bacteria,1MZPS@1224|Proteobacteria,2VUHJ@28216|Betaproteobacteria,2KU2N@206351|Neisseriales	206351|Neisseriales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_125316_1	748247.AZKH_0280	3.972e-251	788.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,2KV3W@206389|Rhodocyclales	206389|Rhodocyclales	I	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
CMS1_k127_125316_0	522306.CAP2UW1_2481	1.674e-265	844.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS1_k127_125316_6	522306.CAP2UW1_2480	1.401e-82	299.0	2B3X8@1|root,31WM6@2|Bacteria,1RFRT@1224|Proteobacteria,2VRRY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
CMS1_k127_125316_3	1144319.PMI16_03517	2.318e-159	512.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,473H1@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NADH dehydrogenase, FAD-containing subunit	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_125316_2	1449049.JONW01000010_gene3730	9.344e-178	563.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2KG62@204458|Caulobacterales	204458|Caulobacterales	S	VWA domain containing CoxE-like protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_125316_10	794846.AJQU01000020_gene2230	1.081e-29	122.0	COG3254@1|root,COG3254@2|Bacteria,1RIRS@1224|Proteobacteria,2UAT0@28211|Alphaproteobacteria,4BJKV@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_125316_11	279714.FuraDRAFT_0533	3.163e-24	110.0	COG3637@1|root,COG3637@2|Bacteria,1N7U7@1224|Proteobacteria,2VRRF@28216|Betaproteobacteria,2KTSV@206351|Neisseriales	206351|Neisseriales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OmpA_membrane
CMS1_k127_125316_4	1198452.Jab_2c29210	1.243e-152	487.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VH9H@28216|Betaproteobacteria,473K5@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS1_k127_125316_9	1095769.CAHF01000013_gene3165	2.472e-35	138.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,2VU50@28216|Betaproteobacteria,474QX@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	cytC2	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_125316_12	323848.Nmul_A2702	2.603e-21	102.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2VUTK@28216|Betaproteobacteria,373BI@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_125316_7	261292.Nit79A3_3433	1.112e-50	184.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,37352@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
CMS1_k127_125316_5	713586.KB900536_gene2717	1.755e-98	325.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1WW35@135613|Chromatiales	135613|Chromatiales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS1_k127_1277798_0	1123504.JQKD01000012_gene1360	0.0	1274.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,4A9KW@80864|Comamonadaceae	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_1277798_9	1000565.METUNv1_00703	3.438e-43	171.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
CMS1_k127_1277798_11	1123368.AUIS01000007_gene2769	1.717e-32	133.0	2F7T9@1|root,3407E@2|Bacteria,1NYX3@1224|Proteobacteria,1SQI5@1236|Gammaproteobacteria,2ND9Z@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1277798_7	1123368.AUIS01000007_gene2770	1.695e-57	213.0	COG0095@1|root,COG0095@2|Bacteria,1RDZE@1224|Proteobacteria,1SQ47@1236|Gammaproteobacteria,2NCC2@225057|Acidithiobacillales	225057|Acidithiobacillales	H	PFAM biotin lipoate A B protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1277798_10	637389.Acaty_c2181	4.125e-35	138.0	2F8JF@1|root,340Y7@2|Bacteria,1NYW2@1224|Proteobacteria,1SQHY@1236|Gammaproteobacteria,2NCY0@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1277798_3	1123392.AQWL01000004_gene2720	2.512e-148	484.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,1KT8K@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
CMS1_k127_1277798_5	292415.Tbd_1253	9.563e-75	256.0	COG2210@1|root,COG2210@2|Bacteria,1QCK1@1224|Proteobacteria,2WE8S@28216|Betaproteobacteria,1KSAI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS1_k127_1277798_1	519989.ECTPHS_10891	2.53e-198	622.0	COG2516@1|root,COG2516@2|Bacteria	2|Bacteria	K	radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS1_k127_1277798_8	204773.HEAR1198	5.982e-46	186.0	COG3193@1|root,COG3193@2|Bacteria,1PP2G@1224|Proteobacteria,2WAB0@28216|Betaproteobacteria,478AN@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
CMS1_k127_1277798_4	713586.KB900536_gene1030	3.874e-118	391.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored,GIDA,Lycopene_cycl
CMS1_k127_1277798_6	1163617.SCD_n00803	1.394e-70	261.0	COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,2VQNY@28216|Betaproteobacteria	28216|Betaproteobacteria	H	lipoate-protein ligase A	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_1277798_2	545276.KB898727_gene272	2.673e-149	479.0	COG1856@1|root,COG1856@2|Bacteria,1R6PW@1224|Proteobacteria,1SKHD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
CMS1_k127_1304717_5	1123393.KB891316_gene2087	1.261e-08	67.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,1KS7I@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_1304717_0	1163617.SCD_n02695	0.0	1471.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_1304717_1	1163617.SCD_n02696	4.529e-106	362.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_1304717_2	1163617.SCD_n02691	6.361e-54	193.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
CMS1_k127_1304717_3	76114.ebA3874	4.273e-25	109.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria,2KX5R@206389|Rhodocyclales	206389|Rhodocyclales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_1304717_4	1168065.DOK_05570	7.962e-15	79.0	COG1937@1|root,COG1937@2|Bacteria,1NFTB@1224|Proteobacteria,1T084@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
CMS1_k127_1403280_1	762376.AXYL_04661	4.557e-128	417.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,3T2AW@506|Alcaligenaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_1403280_0	948106.AWZT01000002_gene6147	6.893e-188	610.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,1K03I@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_1403280_2	1288494.EBAPG3_10810	9.285e-94	315.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,372IH@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_1423865_1	887898.HMPREF0551_0747	2.534e-155	501.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,1K0BK@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_1423865_7	760117.JN27_09080	2.329e-75	272.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria,473VJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_1423865_9	1123401.JHYQ01000022_gene1110	6.968e-29	124.0	COG1309@1|root,COG1309@2|Bacteria,1NBKX@1224|Proteobacteria,1S7KQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1423865_8	1117647.M5M_01075	2.881e-67	245.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RWRX@1236|Gammaproteobacteria,1J6C2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase
CMS1_k127_1423865_2	1123354.AUDR01000014_gene908	2.61e-139	449.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,1KRFY@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS1_k127_1423865_10	5722.XP_001327512.1	1.72e-23	113.0	COG0666@1|root,KOG4177@2759|Eukaryota	5722.XP_001327512.1|-	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1423865_0	1472716.KBK24_0125655	0.0	1214.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,1K1HS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
CMS1_k127_1423865_3	1479237.JMLY01000001_gene2949	3.873e-116	399.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS1_k127_1423865_6	96561.Dole_1528	1.21e-75	258.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42S15@68525|delta/epsilon subdivisions,2WNI1@28221|Deltaproteobacteria,2MNGZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS1_k127_1423865_4	1033802.SSPSH_001573	3.933e-109	397.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
CMS1_k127_1423865_5	1095769.CAHF01000013_gene3288	1.06e-103	345.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria,475IH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_1446395_1	1454004.AW11_00140	3.837e-85	297.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KQH8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
CMS1_k127_1446395_5	983917.RGE_04810	5.42e-20	105.0	2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,2VR1F@28216|Betaproteobacteria,1KKTB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1446395_2	1158150.KB906241_gene1010	1.673e-78	273.0	COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,1RR95@1236|Gammaproteobacteria,1WVUK@135613|Chromatiales	135613|Chromatiales	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
CMS1_k127_1446395_6	1485544.JQKP01000001_gene1146	7.355e-20	102.0	2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,2VW2I@28216|Betaproteobacteria,44W1M@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3301
CMS1_k127_1446395_3	114615.BRADO0654	9.521e-71	247.0	COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,2TV4E@28211|Alphaproteobacteria,3JS5C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_40070	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_1446395_0	1532557.JL37_08035	1.274e-149	490.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VM8X@28216|Betaproteobacteria,3T56U@506|Alcaligenaceae	28216|Betaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS1_k127_1446395_4	266265.Bxe_A3189	1.398e-49	186.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2VQFV@28216|Betaproteobacteria,1K7GC@119060|Burkholderiaceae	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_1446395_7	1336235.JAEG01000020_gene3457	2.223e-06	59.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria,4B7C3@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_1512490_3	639283.Snov_3627	3.952e-50	205.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2U98I@28211|Alphaproteobacteria,3EZPW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
CMS1_k127_1512490_1	1163617.SCD_n02021	1.432e-253	800.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CMS1_k127_1512490_0	640081.Dsui_0365	0.0	2262.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,2KUZA@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_1512490_2	1288494.EBAPG3_9670	1.836e-212	664.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,37253@32003|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS1_k127_1558698_10	196490.AUEZ01000053_gene112	6.778e-24	102.0	COG0329@1|root,COG0329@2|Bacteria,1MWAH@1224|Proteobacteria,2TSXX@28211|Alphaproteobacteria,3JX92@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	dapAch4	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_1558698_12	1116375.VEJY3_00415	3.067e-05	55.0	2BAGG@1|root,323X2@2|Bacteria,1QMCV@1224|Proteobacteria,1TJMG@1236|Gammaproteobacteria,1Y1EE@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1558698_4	983917.RGE_14770	1.054e-129	439.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
CMS1_k127_1558698_3	338969.Rfer_2742	8.559e-177	572.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2VP9Y@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
CMS1_k127_1558698_1	338969.Rfer_2741	1.415e-211	692.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_1558698_2	338966.Ppro_1588	2.252e-203	644.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,43T4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Cytochrome_cB
CMS1_k127_1558698_7	338969.Rfer_2740	1.017e-103	344.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria	1224|Proteobacteria	C	cytochrome	cbcB	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_1558698_6	338969.Rfer_2739	1.95e-105	358.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
CMS1_k127_1558698_8	338969.Rfer_2738	2.123e-54	197.0	COG2204@1|root,COG2204@2|Bacteria,1QZ6X@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_1558698_9	338969.Rfer_2737	1.149e-47	183.0	COG2204@1|root,COG2204@2|Bacteria,1P58Q@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_1558698_11	338969.Rfer_2735	4.009e-13	74.0	COG2204@1|root,COG2204@2|Bacteria,1QZ6X@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_1558698_0	1288494.EBAPG3_15720	0.0	1193.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,37429@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
CMS1_k127_1558698_5	1366050.N234_09615	2.963e-113	374.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,1KBZY@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Quinone oxidoreductase	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1635113_0	338969.Rfer_2156	0.0	1867.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,2WGPV@28216|Betaproteobacteria,4AD3R@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMART alpha amylase catalytic sub domain	treY	-	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
CMS1_k127_1635113_5	543728.Vapar_1983	2.793e-240	786.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2VJDX@28216|Betaproteobacteria,4AA76@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMART alpha amylase catalytic sub domain	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
CMS1_k127_1635113_2	543728.Vapar_1982	0.0	1116.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2VH8E@28216|Betaproteobacteria,4AC1I@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM glycoside hydrolase, family 13 domain protein	-	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS1_k127_1635113_9	396588.Tgr7_2721	1.516e-71	256.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1WW69@135613|Chromatiales	135613|Chromatiales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
CMS1_k127_1635113_7	338969.Rfer_2159	6.812e-92	306.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2WFQP@28216|Betaproteobacteria,4ABHJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
CMS1_k127_1635113_1	338969.Rfer_2160	0.0	1544.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,4ABG1@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMART alpha amylase catalytic sub domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
CMS1_k127_1635113_4	472759.Nhal_2490	4.193e-296	921.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales	135613|Chromatiales	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
CMS1_k127_1635113_3	397945.Aave_2024	5e-324	1026.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2W14D@28216|Betaproteobacteria,4AJPK@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS1_k127_1635113_6	522306.CAP2UW1_1041	4.135e-175	557.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,1KQAG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Lipoprotein-releasing system permease protein	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS1_k127_1635113_8	305700.B447_15136	2.56e-88	298.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KUEU@206389|Rhodocyclales	206389|Rhodocyclales	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS1_k127_1854265_9	864051.BurJ1DRAFT_3327	1.024e-82	276.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
CMS1_k127_1854265_0	864051.BurJ1DRAFT_3329	3.75e-261	814.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria,1KN5P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Fe-S oxidoreductase	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
CMS1_k127_1854265_7	1163617.SCD_n02712	1.253e-101	335.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
CMS1_k127_1854265_12	1163617.SCD_n02713	1.369e-56	198.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS1_k127_1854265_15	1123393.KB891316_gene1847	2.1e-35	143.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,1KT55@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
CMS1_k127_1854265_13	1163617.SCD_n02715	2.469e-56	199.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfur relay protein TusC DsrF	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
CMS1_k127_1854265_11	1163617.SCD_n02716	7.51e-57	200.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,2VR8N@28216|Betaproteobacteria	28216|Betaproteobacteria	P	sulfur relay protein TusD DsrE	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
CMS1_k127_1854265_1	292415.Tbd_2484	4.856e-220	684.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria,1KSR2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS1_k127_1854265_2	292415.Tbd_1369	6.033e-215	677.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS1_k127_1854265_22	864051.BurJ1DRAFT_3337	3.351e-18	92.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1854265_16	1123393.KB891316_gene1853	1.311e-34	147.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,2VVIY@28216|Betaproteobacteria,1KSNR@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Cas6 Crispr	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
CMS1_k127_1854265_14	1485544.JQKP01000005_gene308	5.427e-51	185.0	COG0425@1|root,COG0425@2|Bacteria,1PX23@1224|Proteobacteria,2WCJT@28216|Betaproteobacteria,44W8S@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
CMS1_k127_1854265_10	292415.Tbd_2490	1.809e-67	237.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria,1KS4I@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1854265_8	1485544.JQKP01000005_gene306	2.066e-93	316.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria,44W7U@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS1_k127_1854265_21	794903.OPIT5_07165	3.871e-19	93.0	COG2172@1|root,COG2172@2|Bacteria,46TBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
CMS1_k127_1854265_17	1198452.Jab_2c08600	6.511e-33	138.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,2VW0N@28216|Betaproteobacteria,477SV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_1854265_18	1042375.AFPL01000025_gene1197	1.358e-32	139.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS1_k127_1854265_4	41431.PCC8801_4349	5.408e-138	469.0	COG0642@1|root,COG5001@1|root,COG2205@2|Bacteria,COG5001@2|Bacteria,1G09B@1117|Cyanobacteria,3KGK5@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_1854265_3	1198452.Jab_2c08620	2.648e-143	482.0	COG2208@1|root,COG4252@1|root,COG2208@2|Bacteria,COG4252@2|Bacteria,1QUNZ@1224|Proteobacteria,2WEJF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,SpoIIE
CMS1_k127_1854265_6	1122604.JONR01000009_gene2309	5.327e-114	376.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_1854265_19	1198452.Jab_2c08640	1.229e-23	105.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,2VWJI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	STAS domain	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS,STAS_2
CMS1_k127_1854265_5	375286.mma_0762	4.351e-116	394.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,2VJXF@28216|Betaproteobacteria,476B4@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
CMS1_k127_1854265_20	1267005.KB911258_gene28	2.903e-20	98.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2TTVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3739,Haemagg_act
CMS1_k127_1862534_7	1354722.JQLS01000008_gene2641	7.286e-74	260.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,46QCF@74030|Roseovarius	28211|Alphaproteobacteria	S	Nitrile hydratase, alpha chain	nthA	-	4.2.1.84	ko:K01721,ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
CMS1_k127_1862534_12	1380394.JADL01000002_gene1249	2.367e-37	147.0	2DBV6@1|root,32TY6@2|Bacteria,1N0TC@1224|Proteobacteria,2UCAJ@28211|Alphaproteobacteria,2JXVR@204441|Rhodospirillales	204441|Rhodospirillales	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
CMS1_k127_1862534_13	1380394.JADL01000002_gene1250	2.226e-25	123.0	2DWFS@1|root,32V1J@2|Bacteria,1MZ9A@1224|Proteobacteria,2UDME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
CMS1_k127_1862534_0	331869.BAL199_16353	7.841e-246	773.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,4BPZA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_1862534_8	1207063.P24_00370	2.335e-50	190.0	COG0346@1|root,COG0346@2|Bacteria,1RDDN@1224|Proteobacteria,2U7MP@28211|Alphaproteobacteria,2JV0I@204441|Rhodospirillales	204441|Rhodospirillales	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
CMS1_k127_1862534_3	1207063.P24_00635	5.808e-194	617.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2JP87@204441|Rhodospirillales	204441|Rhodospirillales	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_1862534_10	391937.NA2_08846	4.617e-42	160.0	COG2329@1|root,COG2329@2|Bacteria,1RGVV@1224|Proteobacteria,2U9A3@28211|Alphaproteobacteria,43KD2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Involved in biosynthesis of extracellular polysaccharides	MA20_35560	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_1862534_1	1382304.JNIL01000001_gene1404	1.712e-205	657.0	COG0318@1|root,COG0318@2|Bacteria,1TS8T@1239|Firmicutes,4HAP4@91061|Bacilli,27ANU@186823|Alicyclobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	fadD3	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1862534_6	395494.Galf_1181	3.47e-90	321.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS1_k127_1862534_15	614083.AWQR01000055_gene1978	9.396e-08	63.0	COG0515@1|root,COG2114@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,1PJRR@1224|Proteobacteria,2VHAU@28216|Betaproteobacteria,4AB4Y@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Pkinase
CMS1_k127_1862534_11	290397.Adeh_0308	1.652e-38	158.0	COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,42U81@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_4
CMS1_k127_1862534_5	1218084.BBJK01000061_gene4737	1.404e-133	438.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,1K0IU@119060|Burkholderiaceae	28216|Betaproteobacteria	C	maleylacetate reductase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS1_k127_1862534_16	8479.XP_005301603.1	0.0003039	45.0	2B66N@1|root,2S0KN@2759|Eukaryota,39YG6@33154|Opisthokonta,3BMVF@33208|Metazoa,3D2I9@33213|Bilateria,47ZB1@7711|Chordata,4928P@7742|Vertebrata,4CKZG@8459|Testudines	33208|Metazoa	T	C-type lectin domain family 14 member A	CLEC14A	GO:0001525,GO:0001568,GO:0001667,GO:0001944,GO:0002040,GO:0002042,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0007275,GO:0008150,GO:0009653,GO:0009897,GO:0009986,GO:0009987,GO:0010631,GO:0016020,GO:0016477,GO:0032501,GO:0032502,GO:0035239,GO:0035295,GO:0040011,GO:0043534,GO:0043542,GO:0044425,GO:0044459,GO:0044464,GO:0048514,GO:0048646,GO:0048731,GO:0048856,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0072358,GO:0072359,GO:0090130,GO:0090132,GO:0098552,GO:1990430	-	ko:K17528	-	-	-	-	ko00000,ko04091	-	-	-	Lectin_C
CMS1_k127_1862534_4	1100720.ALKN01000033_gene658	4.309e-188	595.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,4ACEX@80864|Comamonadaceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,SGL
CMS1_k127_1862534_9	1100720.ALKN01000033_gene659	1.021e-45	173.0	COG2863@1|root,COG2863@2|Bacteria,1PFFQ@1224|Proteobacteria,2VXBF@28216|Betaproteobacteria,4AFPX@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_1862534_2	1095769.CAHF01000011_gene2142	1.277e-202	651.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,472S7@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_1862534_14	381666.H16_A1816	6.157e-08	55.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2VU9I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM DoxX family protein	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_1871513_39	1454004.AW11_01750	3.076e-38	148.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1871513_47	1121033.AUCF01000019_gene3696	1.107e-10	73.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2UE39@28211|Alphaproteobacteria,2JXRJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS1_k127_1871513_7	1434929.X946_277	5.088e-204	644.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,1K1N0@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dehydrogenase	odhL	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_1871513_10	1286631.X805_20390	6.464e-170	544.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,1KIX4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_1871513_1	1095769.CAHF01000011_gene2420	0.0	1368.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,472J4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS1_k127_1871513_6	1175306.GWL_23120	6.059e-229	713.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,472V7@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_1871513_22	1095769.CAHF01000011_gene2427	1.235e-94	316.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2VJ6N@28216|Betaproteobacteria,473MV@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	UTRA	frlR	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
CMS1_k127_1871513_12	1288494.EBAPG3_15790	5.052e-153	489.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,371RR@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_1871513_25	34506.g5780	7.991e-89	301.0	COG2513@1|root,KOG1260@2759|Eukaryota,38GWQ@33154|Opisthokonta,3CNF0@33208|Metazoa,3E4JV@33213|Bilateria	33208|Metazoa	C	Phosphoenolpyruvate phosphomutase	-	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
CMS1_k127_1871513_8	1437824.BN940_13156	6.499e-202	634.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria,3T2Q3@506|Alcaligenaceae	28216|Betaproteobacteria	C	also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity	prpC	-	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	-	Citrate_synt
CMS1_k127_1871513_48	1000565.METUNv1_01928	1.334e-08	62.0	2EPEP@1|root,33H1B@2|Bacteria,1NHDJ@1224|Proteobacteria,2VXNY@28216|Betaproteobacteria,2KZUH@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3460
CMS1_k127_1871513_3	1532557.JL37_06940	7.669e-264	821.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,3T3BF@506|Alcaligenaceae	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
CMS1_k127_1871513_42	1255043.TVNIR_0481	2.925e-34	143.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
CMS1_k127_1871513_0	381666.H16_A2638	0.0	1386.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1K16W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_1871513_41	1123487.KB892857_gene2481	6.05e-35	137.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,2KWX7@206389|Rhodocyclales	206389|Rhodocyclales	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CMS1_k127_1871513_23	306281.AJLK01000091_gene3531	6.35e-92	314.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1JJDA@1189|Stigonemataceae	1117|Cyanobacteria	O	Peptide methionine sulfoxide reductase	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_1871513_17	365046.Rta_18130	1.81e-131	427.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2VHCA@28216|Betaproteobacteria,4A9MT@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_1871513_33	396588.Tgr7_0009	5.571e-51	189.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S27K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,MipZ
CMS1_k127_1871513_24	1380394.JADL01000003_gene5182	6.647e-92	308.0	COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2TRP8@28211|Alphaproteobacteria,2JS7D@204441|Rhodospirillales	204441|Rhodospirillales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_1871513_37	158500.BV97_04891	5.049e-47	181.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2TSWT@28211|Alphaproteobacteria,2K1FN@204457|Sphingomonadales	204457|Sphingomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1871513_40	391615.ABSJ01000054_gene1466	1.84e-36	147.0	2EUFJ@1|root,33MXU@2|Bacteria,1NZHB@1224|Proteobacteria,1SQC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
CMS1_k127_1871513_29	391615.ABSJ01000054_gene1467	7.225e-74	254.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,1JAIZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
CMS1_k127_1871513_20	653733.Selin_0436	1.566e-99	343.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_1871513_35	349124.Hhal_1830	4.513e-48	190.0	COG0136@1|root,335ZB@2|Bacteria,1NQEQ@1224|Proteobacteria,1SI1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
CMS1_k127_1871513_26	880073.Calab_2906	1.135e-88	311.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	MA20_22505	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_1871513_31	887062.HGR_09269	3.361e-64	227.0	2BN8J@1|root,32GW0@2|Bacteria,1RH74@1224|Proteobacteria	1224|Proteobacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
CMS1_k127_1871513_14	880072.Desac_2247	3.316e-136	460.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS1_k127_1871513_50	123214.PERMA_0987	1.154e-06	59.0	2ESHP@1|root,33K2C@2|Bacteria,2G59Q@200783|Aquificae	200783|Aquificae	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_1871513_30	1095769.CAHF01000006_gene1897	2.454e-72	256.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,2VR7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1871513_19	1502852.FG94_04152	5.25e-117	395.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,2VHMT@28216|Betaproteobacteria,472WW@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
CMS1_k127_1871513_5	381666.H16_B1609	6.749e-235	752.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,2VJAI@28216|Betaproteobacteria,1K2BP@119060|Burkholderiaceae	28216|Betaproteobacteria	MV	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_1871513_44	1123354.AUDR01000014_gene1080	1.047e-17	92.0	COG4520@1|root,COG4520@2|Bacteria,1RIHU@1224|Proteobacteria,2VTAT@28216|Betaproteobacteria,1KSXJ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
CMS1_k127_1871513_2	257310.BB0501	9.248e-300	930.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,3T2E8@506|Alcaligenaceae	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS1_k127_1871513_18	225937.HP15_3500	9.575e-127	431.0	28HAQ@1|root,2Z7N0@2|Bacteria,1N5R2@1224|Proteobacteria,1RNKD@1236|Gammaproteobacteria,469PU@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS1_k127_1871513_4	292415.Tbd_0850	8.723e-258	805.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,1KRCR@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class I (E and Q), anti-codon binding domain	-	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS1_k127_1871513_36	1038860.AXAP01000129_gene4308	1.352e-47	181.0	COG1546@1|root,COG1546@2|Bacteria,1RHXH@1224|Proteobacteria,2UACN@28211|Alphaproteobacteria,3JQZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the CinA family	MA20_19320	-	-	-	-	-	-	-	-	-	-	-	CinA
CMS1_k127_1871513_9	243365.CV_4129	1.569e-200	642.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,2KQ8G@206351|Neisseriales	206351|Neisseriales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_1871513_13	1038869.AXAN01000081_gene2941	1.071e-146	479.0	COG1215@1|root,COG1215@2|Bacteria,1MXXV@1224|Proteobacteria,2VZ3D@28216|Betaproteobacteria,1K61T@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Chitin synthase	-	-	-	ko:K14666	-	M00664	-	-	ko00000,ko00002,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS1_k127_1871513_16	1230476.C207_01049	6.539e-135	434.0	COG0778@1|root,COG0778@2|Bacteria,1Q7UM@1224|Proteobacteria,2VDZM@28211|Alphaproteobacteria,3JX3R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_1871513_28	525904.Tter_0340	2.87e-78	268.0	COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria	2|Bacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS1_k127_1871513_45	365044.Pnap_0284	8.401e-13	73.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS1_k127_1871513_46	159087.Daro_2080	1.221e-12	72.0	COG5487@1|root,COG5487@2|Bacteria,1NE9T@1224|Proteobacteria,2WAN1@28216|Betaproteobacteria,2KXJR@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS1_k127_1871513_11	1380355.JNIJ01000013_gene338	9.955e-160	512.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2U0HZ@28211|Alphaproteobacteria,3JTHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	MA20_13060	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_1871513_34	1123401.JHYQ01000006_gene67	1.654e-48	174.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,460V9@72273|Thiotrichales	72273|Thiotrichales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_1871513_15	1121033.AUCF01000012_gene831	2.225e-135	442.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,2JQU5@204441|Rhodospirillales	204441|Rhodospirillales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS1_k127_1871513_38	1297865.APJD01000019_gene3237	6.939e-47	179.0	COG0697@1|root,COG0697@2|Bacteria,1R6SK@1224|Proteobacteria,2U4IR@28211|Alphaproteobacteria,3JWNZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1871513_27	748247.AZKH_p0464	1.364e-84	288.0	COG2014@1|root,COG2014@2|Bacteria,1MV5Z@1224|Proteobacteria,2VPCD@28216|Betaproteobacteria,2KUXD@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364,DUF4213
CMS1_k127_1871513_21	709797.CSIRO_3752	6.625e-97	323.0	COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2TTHQ@28211|Alphaproteobacteria,3JSV2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase	MA20_08585	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3
CMS1_k127_1871513_32	1415780.JPOG01000001_gene2764	2.554e-53	199.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1SB6A@1236|Gammaproteobacteria,1XCNG@135614|Xanthomonadales	135614|Xanthomonadales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS1_k127_1883695_2	1123060.JONP01000007_gene5121	3.396e-65	226.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria,2JRKC@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_1883695_0	1038869.AXAN01000045_gene4442	2.237e-159	521.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VIQT@28216|Betaproteobacteria,1JZSR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1883695_1	626887.J057_08481	1.843e-74	259.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,1RPNI@1236|Gammaproteobacteria,464IY@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1886379_36	1207076.ALAT01000168_gene3756	1.028e-16	79.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1Z22G@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_1886379_24	742823.HMPREF9465_00741	6.874e-54	192.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2VSDQ@28216|Betaproteobacteria,4PR43@995019|Sutterellaceae	28216|Betaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS1_k127_1886379_9	640081.Dsui_0359	6.428e-97	320.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria,2KV3R@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS1_k127_1886379_11	1003200.AXXA_10148	8.652e-87	291.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2VHS6@28216|Betaproteobacteria,3T25A@506|Alcaligenaceae	28216|Betaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS1_k127_1886379_31	580332.Slit_0769	1.236e-38	150.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,44VXD@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS1_k127_1886379_6	667632.KB890170_gene3782	6.2e-141	451.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,1K0IX@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS1_k127_1886379_29	1120999.JONM01000019_gene3379	1.633e-45	166.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2VSGE@28216|Betaproteobacteria,2KR9W@206351|Neisseriales	206351|Neisseriales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS1_k127_1886379_27	640081.Dsui_0354	1.777e-50	183.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2VSE6@28216|Betaproteobacteria,2KWKB@206389|Rhodocyclales	206389|Rhodocyclales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS1_k127_1886379_8	580332.Slit_0773	2.796e-99	333.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,44VEP@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS1_k127_1886379_16	1288494.EBAPG3_29870	5.187e-70	238.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,3732Z@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS1_k127_1886379_37	1424334.W822_05385	1.473e-16	85.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,3T4QD@506|Alcaligenaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS1_k127_1886379_34	62928.azo3408	2.448e-29	122.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,2KX1P@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS1_k127_1886379_19	1163617.SCD_n00635	2.1e-65	225.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS1_k127_1886379_28	159087.Daro_0330	4.377e-47	171.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,2KWPF@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS1_k127_1886379_10	323848.Nmul_A0779	7.135e-89	299.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,372JB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS1_k127_1886379_33	557598.LHK_00266	2.291e-34	138.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,2KRHM@206351|Neisseriales	206351|Neisseriales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS1_k127_1886379_21	667632.KB890170_gene3771	1.261e-61	214.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,1K77S@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS1_k127_1886379_14	305700.B447_16031	1.3e-79	269.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,2KW6K@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS1_k127_1886379_30	1120980.JQKH01000034_gene1080	5.834e-42	156.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,2KR4N@206351|Neisseriales	206351|Neisseriales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS1_k127_1886379_13	748247.AZKH_3982	1.134e-81	274.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,2KVMQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS1_k127_1886379_35	497321.C664_09215	1.167e-19	90.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,2KX85@206389|Rhodocyclales	206389|Rhodocyclales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CMS1_k127_1886379_26	1123354.AUDR01000018_gene1233	5.653e-53	192.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,1KRMZ@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	-	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS1_k127_1886379_1	640081.Dsui_0339	1.83e-226	709.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KVBF@206389|Rhodocyclales	206389|Rhodocyclales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_1886379_32	1120999.JONM01000019_gene3396	1.912e-37	141.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,2KRJQ@206351|Neisseriales	206351|Neisseriales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_1886379_38	880072.Desac_1432	5.993e-11	64.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS1_k127_1886379_23	1192124.LIG30_4054	2.88e-56	198.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,1K7P4@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS1_k127_1886379_17	1123487.KB892835_gene3664	6.006e-67	230.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,2KW6N@206389|Rhodocyclales	206389|Rhodocyclales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS1_k127_1886379_7	323848.Nmul_A0791	3.908e-104	341.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,371ZR@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS1_k127_1886379_2	1266925.JHVX01000018_gene1798	7.061e-172	543.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,372HG@32003|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_1886379_22	1288494.EBAPG3_30070	4.732e-59	208.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,3736R@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS1_k127_1886379_15	640511.BC1002_5960	5.692e-72	254.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,2VQJQ@28216|Betaproteobacteria,1KCYS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CMS1_k127_1886379_3	266264.Rmet_0405	1.304e-169	543.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,1K4HH@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Domain of unknown function (DUF4147)	ttuD2	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS1_k127_1886379_25	1565129.JSFF01000008_gene2608	1.193e-53	203.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2Q8H9@267890|Shewanellaceae	1236|Gammaproteobacteria	T	chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal,NIT,PAS_3,PAS_4,PAS_8,PAS_9
CMS1_k127_1886379_18	1245471.PCA10_33200	1.258e-66	237.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,1S4S3@1236|Gammaproteobacteria,1YDSS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_1886379_12	1095769.CAHF01000011_gene2648	3.329e-82	287.0	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VNRV@28216|Betaproteobacteria	28216|Betaproteobacteria	I	esterase	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,COesterase
CMS1_k127_1886379_4	1192124.LIG30_2714	9.782e-146	470.0	COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2VM1T@28216|Betaproteobacteria,1JZPS@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Gentisate 1,2-dioxygenase	nagI	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
CMS1_k127_1886379_5	1123504.JQKD01000007_gene3334	4.996e-144	480.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2VMSN@28216|Betaproteobacteria,4ABYN@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
CMS1_k127_1886379_0	365046.Rta_32440	7.844e-311	967.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_1886379_20	1265502.KB905964_gene1374	2.482e-62	216.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_1895430_5	258594.RPA4522	2.477e-43	165.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2U1D1@28211|Alphaproteobacteria,3JRGI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	haloacid dehalogenase-like hydrolase	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_1895430_4	987059.RBXJA2T_18688	4.977e-108	362.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,1KKER@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp1	-	3.1.3.11,3.1.3.37	ko:K01086,ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
CMS1_k127_1895430_3	675635.Psed_1417	1.363e-149	492.0	COG3954@1|root,COG3954@2|Bacteria,2HHU6@201174|Actinobacteria	201174|Actinobacteria	C	Phosphoribulokinase / Uridine kinase family	prk	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
CMS1_k127_1895430_1	420662.Mpe_A2793	4.376e-178	563.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,1KJFJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	cbbA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CMS1_k127_1895430_0	1123367.C666_01960	5.635e-305	948.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,2KV91@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_1895430_2	1437824.BN940_15296	7.804e-167	529.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,3T31E@506|Alcaligenaceae	28216|Betaproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_1895430_6	1123487.KB892868_gene1302	1.273e-10	71.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,2KUQV@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS1_k127_2054530_1	640081.Dsui_3059	0.0	1058.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,2KU76@206389|Rhodocyclales	206389|Rhodocyclales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_2054530_20	864051.BurJ1DRAFT_1545	1.901e-153	494.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2VKXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS1_k127_2054530_51	1000565.METUNv1_00379	2.414e-58	209.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,2KW2K@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS1_k127_2054530_60	305700.B447_17908	6.442e-27	116.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,2KXBI@206389|Rhodocyclales	206389|Rhodocyclales	J	RNA-binding protein containing KH domain possibly ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CRS1_YhbY
CMS1_k127_2054530_43	497321.C664_02725	1.116e-71	247.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,2KUSV@206389|Rhodocyclales	206389|Rhodocyclales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_2054530_0	1000565.METUNv1_00376	0.0	1699.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,2KUXH@206389|Rhodocyclales	206389|Rhodocyclales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_2054530_12	1232683.ADIMK_0627	1.005e-176	561.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,465QQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040	CPSase_sm_chain,GATase
CMS1_k127_2054530_32	882378.RBRH_03182	3.477e-104	345.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,1K3CP@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS1_k127_2054530_59	279714.FuraDRAFT_2339	1.066e-27	116.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,2KRPT@206351|Neisseriales	206351|Neisseriales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
CMS1_k127_2054530_48	640081.Dsui_3068	1.97e-66	229.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,2KWB1@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_2054530_53	883126.HMPREF9710_00488	1.421e-50	185.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,2VQ6X@28216|Betaproteobacteria,472QH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
CMS1_k127_2054530_19	1071679.BG57_21110	5.385e-156	509.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,1K174@119060|Burkholderiaceae	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CMS1_k127_2054530_35	1348657.M622_09775	8.23e-95	319.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,2KV3J@206389|Rhodocyclales	206389|Rhodocyclales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	ppnK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS1_k127_2054530_22	323848.Nmul_A2423	3.311e-142	458.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,372A2@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CMS1_k127_2054530_27	557598.LHK_02404	1.819e-122	419.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,2KPE7@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS1_k127_2054530_55	1123368.AUIS01000008_gene2139	5.613e-40	166.0	COG5592@1|root,COG5592@2|Bacteria,1NWD3@1224|Proteobacteria,1SPHH@1236|Gammaproteobacteria,2NBRT@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
CMS1_k127_2054530_54	1123354.AUDR01000017_gene86	7.026e-47	175.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,1KRM6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	GrpE	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_2054530_2	557598.LHK_02739	0.0	1024.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KPV9@206351|Neisseriales	206351|Neisseriales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_2054530_10	522306.CAP2UW1_0504	5.329e-185	584.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,1KPRY@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_2054530_25	1005048.CFU_3656	2.747e-127	418.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,476W0@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_2054530_8	522306.CAP2UW1_0506	5.636e-222	696.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,1KPS3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS1_k127_2054530_39	1163617.SCD_n00897	2.484e-87	300.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
CMS1_k127_2054530_23	640081.Dsui_3086	2.24e-141	471.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KVPI@206389|Rhodocyclales	206389|Rhodocyclales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_2054530_49	1266925.JHVX01000009_gene94	3.555e-64	229.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3731S@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS1_k127_2054530_45	1163617.SCD_n00893	8.467e-70	245.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
CMS1_k127_2054530_14	795666.MW7_1326	3.241e-170	543.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,1KIDZ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_2054530_6	261292.Nit79A3_2464	5.964e-243	759.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,3723J@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS1_k127_2054530_57	1131553.JIBI01000021_gene265	9.322e-32	130.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,3739Y@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS1_k127_2054530_62	159087.Daro_0874	3.996e-22	103.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,2KWXH@206389|Rhodocyclales	206389|Rhodocyclales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
CMS1_k127_2054530_24	1123487.KB892838_gene3864	5.857e-138	452.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KV9G@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CMS1_k127_2054530_21	1000565.METUNv1_02666	5.115e-144	462.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,2KUCF@206389|Rhodocyclales	206389|Rhodocyclales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_2054530_30	1123367.C666_02830	1.037e-104	364.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,2KV5S@206389|Rhodocyclales	206389|Rhodocyclales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS1_k127_2054530_7	305700.B447_01196	9.354e-223	694.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,2KUYW@206389|Rhodocyclales	206389|Rhodocyclales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2054530_46	1163617.SCD_n00880	1.627e-68	243.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS1_k127_2054530_34	1485544.JQKP01000003_gene249	4.107e-97	326.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,44V8K@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_2054530_28	1121035.AUCH01000014_gene2421	2.338e-120	422.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
CMS1_k127_2054530_13	323848.Nmul_A1917	4.131e-172	546.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,3729Z@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_2054530_17	265072.Mfla_1703	1.731e-163	533.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,2KMFH@206350|Nitrosomonadales	206350|Nitrosomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_2054530_33	1095769.CAHF01000011_gene2553	2.594e-103	351.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,472UP@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_2054530_5	864051.BurJ1DRAFT_3947	1.172e-245	765.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,1KIWD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS1_k127_2054530_37	62928.azo1038	6.302e-93	317.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,2KVMZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_2054530_40	62928.azo1037	1.735e-83	291.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,2KV5D@206389|Rhodocyclales	206389|Rhodocyclales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
CMS1_k127_2054530_4	404589.Anae109_1032	1.26e-254	817.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
CMS1_k127_2054530_11	398527.Bphyt_2537	7.516e-178	567.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,1K2BU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS1_k127_2054530_31	1163617.SCD_n01806	1.069e-104	352.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS1_k127_2054530_52	1304883.KI912532_gene1967	1.348e-54	203.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,2KWT1@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
CMS1_k127_2054530_15	748247.AZKH_0807	6.204e-164	531.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,2KUKY@206389|Rhodocyclales	206389|Rhodocyclales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_2054530_9	265072.Mfla_1620	3.607e-202	636.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,2KMH4@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS1_k127_2054530_56	1163617.SCD_n01810	2.71e-38	156.0	COG1426@1|root,COG4787@1|root,COG1426@2|Bacteria,COG4787@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Transcriptional regulator	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CMS1_k127_2054530_47	640081.Dsui_3144	8.016e-68	244.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,2KW79@206389|Rhodocyclales	206389|Rhodocyclales	NU	type 4 pilus biogenesis protein	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
CMS1_k127_2054530_16	1000565.METUNv1_00752	7.553e-164	522.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,2KVXU@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_2054530_44	1095769.CAHF01000011_gene2402	4.731e-71	243.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,4741A@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS1_k127_2054530_36	228410.NE1022	9.476e-95	326.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,3728I@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS1_k127_2054530_18	62928.azo0915	1.465e-161	513.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,2KUDJ@206389|Rhodocyclales	206389|Rhodocyclales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS1_k127_2054530_42	1500897.JQNA01000001_gene5773	2.403e-72	258.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,1K0UG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM HhH-GPD family protein	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS1_k127_2054530_26	375286.mma_0185	2.754e-123	404.0	2C7F6@1|root,2Z8AK@2|Bacteria,1PEE5@1224|Proteobacteria,2VKQ6@28216|Betaproteobacteria,476M3@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2054530_41	62928.azo1442	2.027e-79	270.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,2KW5S@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_2054530_61	1123393.KB891332_gene2680	3.614e-22	98.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VVKE@28216|Betaproteobacteria,1KTBM@119069|Hydrogenophilales	119069|Hydrogenophilales	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_2054530_63	402881.Plav_0741	1.724e-10	72.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_2054530_3	338969.Rfer_0831	3.741e-262	839.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,4ACBR@80864|Comamonadaceae	28216|Betaproteobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CMS1_k127_2054530_38	991905.SL003B_2483	2.313e-91	316.0	28N0F@1|root,2ZB6V@2|Bacteria,1R4J3@1224|Proteobacteria,2VCSJ@28211|Alphaproteobacteria,4BSIC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS1_k127_2054530_50	909943.HIMB100_00014820	5.333e-62	222.0	28H7B@1|root,2Z7JJ@2|Bacteria,1MX57@1224|Proteobacteria,2TQZS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
CMS1_k127_2054530_29	1288494.EBAPG3_24560	7.314e-115	383.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,GAF_2,HD
CMS1_k127_2054530_58	365046.Rta_37340	3.67e-29	126.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,4AF3V@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CMS1_k127_205662_4	864051.BurJ1DRAFT_3660	6.396e-92	309.0	COG0861@1|root,COG0861@2|Bacteria,1QZU6@1224|Proteobacteria,2VJDD@28216|Betaproteobacteria,1KPIP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	membrane protein, terc	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_205662_1	395965.Msil_1712	1.403e-283	880.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,3NASQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	F	formate-tetrahydrofolate ligase activity	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS1_k127_205662_0	1095769.CAHF01000011_gene2631	0.0	1414.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,472B9@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS1_k127_205662_2	1095769.CAHF01000011_gene2632	7.085e-269	839.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,473CK@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_205662_3	1288494.EBAPG3_26320	2.205e-254	805.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,37225@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
CMS1_k127_2062609_7	1545915.JROG01000001_gene557	8.278e-06	48.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2K15R@204457|Sphingomonadales	204457|Sphingomonadales	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
CMS1_k127_2062609_0	1500897.JQNA01000001_gene5617	8.37e-210	658.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VK3Y@28216|Betaproteobacteria,1K3JP@119060|Burkholderiaceae	28216|Betaproteobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.4.1.24	ko:K16846	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	GD_AH_C
CMS1_k127_2062609_1	795666.MW7_3395	3.635e-163	532.0	COG0028@1|root,COG0028@2|Bacteria,1R6FF@1224|Proteobacteria,2WF6X@28216|Betaproteobacteria,1KHZB@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_2062609_3	713586.KB900536_gene710	3.909e-116	377.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales	1236|Gammaproteobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_3,Fer4_17,Fer4_8
CMS1_k127_2062609_5	426355.Mrad2831_5988	2.335e-27	124.0	COG2142@1|root,COG2142@2|Bacteria,1MZKE@1224|Proteobacteria,2UDDU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	succinate dehydrogenase	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_2062609_4	713586.KB900536_gene708	1.633e-35	144.0	COG2009@1|root,COG2009@2|Bacteria,1N8VA@1224|Proteobacteria	1224|Proteobacteria	C	succinate dehydrogenase	-	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_2062609_2	795666.MW7_3399	4.35e-140	460.0	COG1951@1|root,COG1951@2|Bacteria,1MW8J@1224|Proteobacteria,2VKI4@28216|Betaproteobacteria,1KHN1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Fumarate hydratase (Fumerase)	ttdA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
CMS1_k127_2062609_6	1454004.AW11_03245	7.111e-16	81.0	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,2WGJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
CMS1_k127_2091216_15	305700.B447_12929	8.327e-81	273.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,2KU9A@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS1_k127_2091216_30	556268.OFAG_01715	2.342e-16	91.0	COG3203@1|root,COG3203@2|Bacteria,1N04Q@1224|Proteobacteria,2VPHP@28216|Betaproteobacteria,478HJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
CMS1_k127_2091216_17	85643.Tmz1t_1230	3.808e-70	244.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,2KUDE@206389|Rhodocyclales	206389|Rhodocyclales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
CMS1_k127_2091216_21	1144342.PMI40_02839	7.101e-63	218.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,4736Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	regulator of disulfide bond formation	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS1_k127_2091216_19	395019.Bmul_2704	3.673e-65	228.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,1JZQF@119060|Burkholderiaceae	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS1_k127_2091216_22	1163617.SCD_n02521	2.734e-57	209.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS1_k127_2091216_4	580332.Slit_2455	2.345e-159	511.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,44V0R@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_2091216_23	640081.Dsui_1332	1.466e-53	198.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VVJ7@28216|Betaproteobacteria,2KX2H@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2091216_25	640081.Dsui_1333	2.412e-47	173.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,2KWWR@206389|Rhodocyclales	206389|Rhodocyclales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_2091216_20	522306.CAP2UW1_3027	9.539e-64	219.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1KQ1R@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
CMS1_k127_2091216_8	582744.Msip34_0065	1.241e-116	402.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,2KMHH@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS1_k127_2091216_9	1163617.SCD_n02515	3.112e-114	381.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_2091216_1	1163617.SCD_n02514	5.315e-180	572.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
CMS1_k127_2091216_11	1380394.JADL01000002_gene1281	4.491e-111	371.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,2TRG9@28211|Alphaproteobacteria,2JQV5@204441|Rhodospirillales	204441|Rhodospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2091216_7	443144.GM21_0054	8.722e-124	407.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2091216_27	1089552.KI911559_gene282	1.472e-44	174.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U7C6@28211|Alphaproteobacteria,2JSNY@204441|Rhodospirillales	204441|Rhodospirillales	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	chaC	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
CMS1_k127_2091216_3	497321.C664_10782	4.576e-164	535.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,2KV7J@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase subunit GlcD	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_2091216_26	748247.AZKH_3297	1.916e-46	184.0	COG0683@1|root,COG0683@2|Bacteria,1R6HB@1224|Proteobacteria,2VVCV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2091216_14	1380394.JADL01000010_gene4335	5.448e-90	305.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,2JQKY@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_2091216_13	596154.Alide2_1043	2.904e-92	319.0	COG2271@1|root,COG2271@2|Bacteria,1R8Q1@1224|Proteobacteria,2VKPK@28216|Betaproteobacteria,4ABJB@80864|Comamonadaceae	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2091216_29	1168065.DOK_16638	7.038e-33	145.0	COG2050@1|root,COG2050@2|Bacteria,1RHP8@1224|Proteobacteria,1SPYG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_2091216_24	589865.DaAHT2_2423	3.901e-50	187.0	COG1462@1|root,COG1462@2|Bacteria,1Q4KN@1224|Proteobacteria,42U33@68525|delta/epsilon subdivisions,2WQXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
CMS1_k127_2091216_28	84531.JMTZ01000073_gene2105	4.569e-35	144.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1X6RA@135614|Xanthomonadales	135614|Xanthomonadales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Abhydrolase_8
CMS1_k127_2091216_12	522306.CAP2UW1_1931	7.178e-96	327.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria	28216|Betaproteobacteria	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
CMS1_k127_2091216_18	396588.Tgr7_3252	1.41e-69	250.0	2F2KZ@1|root,33VHM@2|Bacteria,1NV1E@1224|Proteobacteria,1SN95@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2091216_6	1254432.SCE1572_19815	2.607e-132	439.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2YZNI@29|Myxococcales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
CMS1_k127_2091216_5	1254432.SCE1572_19820	2.334e-147	496.0	COG4864@1|root,COG4864@2|Bacteria,1MWP0@1224|Proteobacteria,42N9I@68525|delta/epsilon subdivisions,2WK7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS1_k127_2091216_32	113395.AXAI01000032_gene707	3.661e-12	77.0	COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria,2U63Z@28211|Alphaproteobacteria,3JYEK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_2091216_31	1385935.N836_16265	1.919e-13	81.0	COG0664@1|root,COG0664@2|Bacteria,1G9GW@1117|Cyanobacteria	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_2091216_16	1301098.PKB_3521	7.352e-79	269.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,1S2K3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-Transferase	yliJ	GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS1_k127_2091216_0	47839.CCAU010000017_gene3988	1.207e-228	738.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,2354G@1762|Mycobacteriaceae	201174|Actinobacteria	E	gamma-glutamyltransferase	ggtA	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_2091216_10	1169143.KB911035_gene1794	2.014e-112	389.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VM08@28216|Betaproteobacteria,1K6AP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Zinc-binding dehydrogenase	adh	-	1.1.1.1,1.1.1.258	ko:K12957,ko:K13953,ko:K19961	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00930,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00930,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R05283,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2091216_2	395493.BegalDRAFT_0308	3.894e-170	539.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,4602W@72273|Thiotrichales	72273|Thiotrichales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_2098196_1	292415.Tbd_1622	1.161e-103	358.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KTCY@119069|Hydrogenophilales	119069|Hydrogenophilales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CMS1_k127_2098196_2	1042375.AFPL01000036_gene3002	2.545e-86	290.0	COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,1RYPQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phenylacetic acid degradation protein PaaY	paaY	GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
CMS1_k127_2098196_3	1278073.MYSTI_05766	6.16e-59	210.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria,2Z33C@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_2098196_0	257310.BB4614	1.65e-116	381.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,3T1Q4@506|Alcaligenaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	4.2.1.17	ko:K01692,ko:K01715,ko:K07534	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01220,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212,map01220	M00032,M00087,M00540	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R05600,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02034,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_210414_3	748280.NH8B_0862	5.005e-37	146.0	COG2259@1|root,COG2259@2|Bacteria,1RM2W@1224|Proteobacteria,2VWVB@28216|Betaproteobacteria,2KU3J@206351|Neisseriales	206351|Neisseriales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_210414_2	626418.bglu_2p0960	5.992e-42	167.0	COG3219@1|root,COG3219@2|Bacteria,1N2ED@1224|Proteobacteria,2VV6U@28216|Betaproteobacteria,1KH8V@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
CMS1_k127_210414_1	1218075.BAYA01000004_gene1301	2.647e-103	347.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKD3@28216|Betaproteobacteria,1K0J2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF2063,DUF692
CMS1_k127_210414_4	1349767.GJA_4134	1.852e-12	78.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2VWC8@28216|Betaproteobacteria,478B2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
CMS1_k127_210414_0	358220.C380_09610	8.823e-115	387.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AAGH@80864|Comamonadaceae	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH
CMS1_k127_2145814_13	640081.Dsui_1042	9.473e-52	186.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,2KV21@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_2145814_3	1454004.AW11_00136	1.244e-129	424.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,1KQMM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS1_k127_2145814_12	1158292.JPOE01000002_gene2083	8.086e-57	213.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
CMS1_k127_2145814_11	1158292.JPOE01000005_gene1018	3.887e-60	213.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2VTGX@28216|Betaproteobacteria,1KKWK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_2145814_4	439235.Dalk_3101	4.597e-119	396.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,42UB1@68525|delta/epsilon subdivisions,2WQ1B@28221|Deltaproteobacteria,2MNNK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2145814_7	439235.Dalk_3102	1.328e-85	292.0	COG0559@1|root,COG0559@2|Bacteria,1PFYF@1224|Proteobacteria,43E9Q@68525|delta/epsilon subdivisions,2X03G@28221|Deltaproteobacteria,2MNWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2145814_5	439235.Dalk_3103	9.374e-115	380.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MJX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2145814_8	986075.CathTA2_1528	1.147e-84	287.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_2145814_6	439235.Dalk_3105	7.127e-110	376.0	COG0411@1|root,COG0411@2|Bacteria,1R9G9@1224|Proteobacteria,42QH8@68525|delta/epsilon subdivisions,2WKUJ@28221|Deltaproteobacteria,2MNGW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2145814_2	439235.Dalk_3104	3.145e-228	720.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2145814_1	62928.azo1661	0.0	1163.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,2KUDI@206389|Rhodocyclales	206389|Rhodocyclales	CM	Acyl-CoA synthetase (NDP forming)	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CMS1_k127_2145814_10	580332.Slit_0762	1.972e-65	229.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2VR2H@28216|Betaproteobacteria,44VUV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS1_k127_2145814_9	1097668.BYI23_A024510	5.916e-72	254.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria,1K1QQ@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS1_k127_2145814_0	1095769.CAHF01000004_gene2744	0.0	1172.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,4734N@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_2145814_14	522306.CAP2UW1_3495	7.393e-19	86.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,1KPWG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_2186939_7	497321.C664_06623	3.015e-84	283.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,2KV2B@206389|Rhodocyclales	206389|Rhodocyclales	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS1_k127_2186939_0	640081.Dsui_2909	3.65e-223	696.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VI7S@28216|Betaproteobacteria,2KXUT@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2186939_10	323848.Nmul_A1553	2.973e-31	140.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,373I3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
CMS1_k127_2186939_3	1163617.SCD_n01749	1.232e-135	451.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
CMS1_k127_2186939_9	1218084.BBJK01000054_gene4195	1.255e-49	183.0	COG2076@1|root,COG2076@2|Bacteria,1RHUW@1224|Proteobacteria,2VSEI@28216|Betaproteobacteria,1K7S1@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
CMS1_k127_2186939_2	522306.CAP2UW1_3296	2.161e-159	512.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KQ9V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_2186939_4	1163617.SCD_n01752	2.686e-132	447.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Pfam Glycosyl transferase family 2	arnC	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
CMS1_k127_2186939_6	1286093.C266_00220	2.127e-111	368.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,2VKAI@28216|Betaproteobacteria,1K0VV@119060|Burkholderiaceae	28216|Betaproteobacteria	J	PFAM formyl transferase domain protein	pmrIa	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_2186939_1	1158292.JPOE01000002_gene2806	4.987e-171	558.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJV2@28216|Betaproteobacteria,1KKIW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	NAD(P)H-binding	pmrIb	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_2186939_5	1163617.SCD_n01755	6.159e-128	437.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_2186939_8	404589.Anae109_0481	3.777e-80	287.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,42WB3@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Alpha beta hydrolase	dehH	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_2207276_26	580332.Slit_0072	8.057e-09	58.0	2A8Y5@1|root,30Y1T@2|Bacteria,1PJX0@1224|Proteobacteria,2W3X5@28216|Betaproteobacteria,44WJX@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2207276_16	164757.Mjls_4433	8.939e-64	243.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_2207276_0	1095769.CAHF01000005_gene1469	2.045e-287	897.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria	28216|Betaproteobacteria	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
CMS1_k127_2207276_22	62928.azo2606	1.492e-26	114.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,2VWEG@28216|Betaproteobacteria,2KZ8A@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
CMS1_k127_2207276_9	580332.Slit_1271	4.362e-104	364.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS1_k127_2207276_20	1095769.CAHF01000013_gene3234	1.271e-43	169.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2207276_15	1095769.CAHF01000013_gene3233	1.023e-76	273.0	COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PEGA
CMS1_k127_2207276_25	439235.Dalk_1261	1.499e-15	89.0	2AF4E@1|root,31534@2|Bacteria,1NEPN@1224|Proteobacteria,42WGJ@68525|delta/epsilon subdivisions,2WRTJ@28221|Deltaproteobacteria,2MM2R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS1_k127_2207276_11	95619.PM1_0217190	4.969e-102	356.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	transport system involved in gliding motility, auxiliary component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS1_k127_2207276_14	1123073.KB899242_gene1477	2.799e-81	291.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS1_k127_2207276_8	240016.ABIZ01000001_gene3117	4.81e-111	369.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_2207276_10	358220.C380_16430	3.16e-102	342.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,4AAYT@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
CMS1_k127_2207276_1	639283.Snov_4338	6.616e-219	689.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3EZ6H@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_2207276_7	395495.Lcho_4158	2.848e-111	389.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,1KKB6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_2207276_6	543913.D521_0390	1.575e-121	403.0	COG0589@1|root,COG0861@1|root,COG0589@2|Bacteria,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,1KQ0Z@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_2207276_5	402881.Plav_2105	1.808e-132	433.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TSIV@28211|Alphaproteobacteria,1JMZZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Fructose-bisphosphate aldolase class-I	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
CMS1_k127_2207276_4	1286093.C266_23778	2.583e-137	441.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,1K26Y@119060|Burkholderiaceae	28216|Betaproteobacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS1_k127_2207276_18	305700.B447_04078	8.576e-61	214.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,2KW4U@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS1_k127_2207276_12	1121035.AUCH01000003_gene1368	9.893e-93	322.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,2KUUI@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS1_k127_2207276_21	62928.azo0471	4.346e-30	129.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,2KWND@206389|Rhodocyclales	206389|Rhodocyclales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS1_k127_2207276_3	1123060.JONP01000011_gene3108	1.753e-154	506.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2TS7J@28211|Alphaproteobacteria,2JQWQ@204441|Rhodospirillales	204441|Rhodospirillales	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
CMS1_k127_2207276_13	398525.KB900701_gene4504	3.814e-85	295.0	COG0730@1|root,COG0730@2|Bacteria,1MVYH@1224|Proteobacteria,2TTY0@28211|Alphaproteobacteria,3JS7X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	MA20_27970	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_2207276_2	257310.BB1966	7.132e-175	558.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,3T3DF@506|Alcaligenaceae	28216|Betaproteobacteria	NT	DinB superfamily	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS1_k127_2207276_19	555778.Hneap_1517	2.807e-51	188.0	COG0454@1|root,COG0456@2|Bacteria,1RKJA@1224|Proteobacteria,1T1ZP@1236|Gammaproteobacteria,1X1TJ@135613|Chromatiales	135613|Chromatiales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS1_k127_2207276_17	1297742.A176_03999	1.079e-61	216.0	COG3791@1|root,COG3791@2|Bacteria,1NC41@1224|Proteobacteria,4337H@68525|delta/epsilon subdivisions,2WXGD@28221|Deltaproteobacteria,2Z206@29|Myxococcales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2311957_11	1172185.KB911518_gene2685	4.985e-88	302.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4FVXQ@85025|Nocardiaceae	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_2311957_17	405948.SACE_4576	5.956e-12	71.0	COG0662@1|root,COG0662@2|Bacteria,2IN75@201174|Actinobacteria,4E72Y@85010|Pseudonocardiales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_2311957_3	1231391.AMZF01000037_gene588	3.123e-176	566.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2VND1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_2311957_9	196490.AUEZ01000007_gene5115	6.876e-95	321.0	COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2U12U@28211|Alphaproteobacteria,3JX1N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2311957_15	331869.BAL199_24559	2.166e-48	178.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2U4YP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_2311957_7	443598.AUFA01000039_gene5989	7.893e-107	353.0	COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2TT8T@28211|Alphaproteobacteria,3JRKQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	MA20_14295	-	1.13.11.37	ko:K04098	ko00361,ko00362,ko01100,ko01120,map00361,map00362,map01100,map01120	-	R03891,R04061	RC00388,RC01016	ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
CMS1_k127_2311957_10	1380394.JADL01000002_gene1775	1.876e-90	308.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2TSUU@28211|Alphaproteobacteria,2JPHD@204441|Rhodospirillales	204441|Rhodospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
CMS1_k127_2311957_13	264198.Reut_C6036	5.301e-66	236.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2VN9Q@28216|Betaproteobacteria,1K24N@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2311957_14	1005048.CFU_0108	3.489e-62	223.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,2VIYU@28216|Betaproteobacteria,474EB@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
CMS1_k127_2311957_16	292415.Tbd_1388	2.4e-32	146.0	COG0517@1|root,COG0517@2|Bacteria,1QTXQ@1224|Proteobacteria,2VWDB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_2311957_4	1005048.CFU_4103	1.438e-160	522.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,4737T@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2311957_5	1123257.AUFV01000003_gene1169	3.809e-128	421.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,1SM3A@1236|Gammaproteobacteria,1XDFJ@135614|Xanthomonadales	135614|Xanthomonadales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2311957_8	944435.AXAJ01000002_gene4485	7.928e-96	319.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria,1K2Q4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2311957_12	326297.Sama_2951	2.172e-86	313.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,2Q9DZ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
CMS1_k127_2311957_2	1454004.AW11_01300	6.705e-186	587.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_2311957_1	1157708.KB907453_gene4250	4.571e-316	976.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,4A9VY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
CMS1_k127_2311957_0	1123073.KB899242_gene1461	0.0	1021.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1XA61@135614|Xanthomonadales	135614|Xanthomonadales	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
CMS1_k127_2311957_6	640081.Dsui_1564	6.612e-125	419.0	COG4191@1|root,COG5000@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV2U@206389|Rhodocyclales	206389|Rhodocyclales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_7,PAS_8,PAS_9
CMS1_k127_2318929_3	765913.ThidrDRAFT_4248	5.745e-175	558.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,1X05D@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
CMS1_k127_2318929_2	1400524.KL370779_gene346	2.611e-178	569.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,4BQIN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_2318929_15	1168059.KB899087_gene2278	2.129e-21	98.0	COG2863@1|root,COG2863@2|Bacteria,1PUQA@1224|Proteobacteria,2V69G@28211|Alphaproteobacteria,3F07B@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_2318929_0	395495.Lcho_1988	2.833e-305	960.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KJ3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_2318929_8	760117.JN27_00405	1.912e-68	235.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ9M@28216|Betaproteobacteria,474CY@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	iorA	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_2318929_12	1095769.CAHF01000005_gene1479	9.793e-48	175.0	COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,2VSX8@28216|Betaproteobacteria,474SJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	enzyme involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_2318929_11	1265502.KB905997_gene3341	1.971e-51	187.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,4ADEE@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS1_k127_2318929_6	1205680.CAKO01000040_gene540	2.849e-155	500.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2JPM3@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
CMS1_k127_2318929_4	1123354.AUDR01000015_gene349	1.887e-170	546.0	COG1488@1|root,COG1488@2|Bacteria,1PNWY@1224|Proteobacteria,2W9DN@28216|Betaproteobacteria,1KS4Z@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	-	-	-	-	-	-	-	-	-	-	NAPRTase
CMS1_k127_2318929_1	1244869.H261_06576	1.119e-190	614.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales	204441|Rhodospirillales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS1_k127_2318929_5	426117.M446_5093	1.188e-160	525.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,1JUD1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_2318929_18	1157490.EL26_15995	4.026e-06	59.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4
CMS1_k127_2318929_10	1207063.P24_14334	4.914e-52	189.0	COG2030@1|root,COG2030@2|Bacteria,1RH7U@1224|Proteobacteria,2U50J@28211|Alphaproteobacteria,2JXEP@204441|Rhodospirillales	204441|Rhodospirillales	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2318929_17	1123247.AUIJ01000018_gene2706	2.198e-15	79.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,2UG4S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2318929_9	243365.CV_0394	4.095e-52	194.0	COG0500@1|root,COG2226@2|Bacteria,1RGJA@1224|Proteobacteria,2VTNT@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
CMS1_k127_2318929_7	1123255.JHYS01000004_gene966	4.522e-101	338.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,2VRHY@28216|Betaproteobacteria,4AFE9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
CMS1_k127_2318929_16	292.DM42_6039	1.583e-20	94.0	2EIDG@1|root,33C4V@2|Bacteria,1N0P4@1224|Proteobacteria,2VYCP@28216|Betaproteobacteria,1K9BA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2318929_13	420662.Mpe_A0682	2.087e-42	161.0	arCOG08935@1|root,32Z08@2|Bacteria,1R3HB@1224|Proteobacteria,2VYJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2318929_14	365044.Pnap_2766	5.21e-27	111.0	COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM GYD family protein	-	-	-	-	-	-	-	-	-	-	-	-	GYD
CMS1_k127_2356396_10	296591.Bpro_3554	3.617e-54	195.0	COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,2VT83@28216|Betaproteobacteria,4AEKN@80864|Comamonadaceae	28216|Betaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
CMS1_k127_2356396_14	1168059.KB899087_gene1386	3.972e-09	68.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TS46@28211|Alphaproteobacteria,3F0PV@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_2356396_15	1123023.JIAI01000001_gene6601	5.286e-08	63.0	COG3090@1|root,COG3090@2|Bacteria,2H0G8@201174|Actinobacteria,4E7KB@85010|Pseudonocardiales	201174|Actinobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_2356396_9	62928.azo0921	1.32e-73	263.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,2KY3Z@206389|Rhodocyclales	206389|Rhodocyclales	G	TRAP-type C4-dicarboxylate transport system, large permease	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
CMS1_k127_2356396_1	1163617.SCD_n01100	5.394e-172	563.0	COG2972@1|root,COG5001@1|root,COG2972@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKCJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,HAMP
CMS1_k127_2356396_13	305700.B447_20241	2.226e-24	109.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2VVST@28216|Betaproteobacteria,2KXHQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
CMS1_k127_2356396_0	859657.RPSI07_mp0747	1.717e-183	595.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,2VMKQ@28216|Betaproteobacteria,1K5CU@119060|Burkholderiaceae	28216|Betaproteobacteria	H	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_2356396_4	1038860.AXAP01000014_gene874	1.209e-119	402.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3JWN0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_2356396_7	1187851.A33M_2603	3.726e-106	351.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3FD1Y@34008|Rhodovulum	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2356396_12	999630.TUZN_1203	1.107e-35	157.0	COG0411@1|root,arCOG00925@2157|Archaea	2157|Archaea	E	COG0411 ABC-type branched-chain amino acid transport systems ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_2356396_5	1380394.JADL01000004_gene5933	9.01e-110	363.0	COG4177@1|root,COG4177@2|Bacteria,1PSHZ@1224|Proteobacteria,2TVQQ@28211|Alphaproteobacteria,2JVEV@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_2356396_6	1187851.A33M_2606	8.728e-108	356.0	COG0559@1|root,COG0559@2|Bacteria,1R5JM@1224|Proteobacteria,2TUSY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2356396_3	1380394.JADL01000004_gene5935	4.871e-163	526.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria,2JR5U@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_2356396_11	395495.Lcho_1209	3.104e-40	168.0	COG3945@1|root,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,1KKSC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS1_k127_2356396_8	1121106.JQKB01000010_gene561	5.256e-83	295.0	COG2084@1|root,COG2084@2|Bacteria,1R889@1224|Proteobacteria,2TUEY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_2356396_2	426355.Mrad2831_5856	4.509e-168	535.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,1JTKB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_2403399_14	634956.Geoth_1655	8.338e-06	49.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1WFK4@129337|Geobacillus	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS1_k127_2403399_9	296591.Bpro_2056	9.962e-51	187.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
CMS1_k127_2403399_5	296591.Bpro_1464	2.846e-121	404.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2VJKU@28216|Betaproteobacteria,4AB6Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_2403399_8	1211114.ALIP01000083_gene1541	1.628e-65	231.0	COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_2403399_13	1380346.JNIH01000018_gene5299	1.66e-23	113.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_2403399_0	1095769.CAHF01000018_gene846	5.612e-230	725.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VHEI@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2403399_6	472759.Nhal_3413	2.607e-113	374.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X250@135613|Chromatiales	135613|Chromatiales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_2403399_10	1380355.JNIJ01000004_gene2837	1.959e-43	166.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2TSFV@28211|Alphaproteobacteria,3JRG8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_2403399_3	595537.Varpa_4521	3.202e-164	526.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,4ACEX@80864|Comamonadaceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,SGL
CMS1_k127_2403399_2	1007105.PT7_1206	1.261e-173	554.0	COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2VIIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2403399_12	331869.BAL199_17958	4.082e-39	151.0	2DS7S@1|root,33EWX@2|Bacteria,1NDGE@1224|Proteobacteria,2UH4Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2403399_4	631454.N177_1057	9.784e-144	467.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TQVT@28211|Alphaproteobacteria,1JNU5@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_2403399_11	1380367.JIBC01000008_gene1210	8.352e-40	154.0	COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,2U96V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_2403399_1	631454.N177_1059	4.7e-198	625.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,1JNDR@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_2403399_7	1095769.CAHF01000022_gene96	5.143e-87	297.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472RR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM EAL domain, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
CMS1_k127_2418950_7	1123508.JH636452_gene6925	8.15e-85	299.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2J2DQ@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,dCache_1
CMS1_k127_2418950_0	338969.Rfer_3852	4.236e-243	757.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,4AFB1@80864|Comamonadaceae	28216|Betaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS1_k127_2418950_9	338969.Rfer_3853	1.132e-50	183.0	COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,2VU90@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
CMS1_k127_2418950_5	399739.Pmen_4107	6.388e-99	340.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,1YD8I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	Inner membrane protein CreD	creD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
CMS1_k127_2418950_8	1000565.METUNv1_01904	3.344e-51	189.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,2KW82@206389|Rhodocyclales	28216|Betaproteobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	epsR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_2418950_1	1117647.M5M_15825	1.093e-136	455.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,1J9SB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_2418950_11	1165841.SULAR_02403	2.181e-11	68.0	2DFKD@1|root,2ZS7E@2|Bacteria,1P5EA@1224|Proteobacteria	1224|Proteobacteria	S	Pfam:DUF1049	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
CMS1_k127_2418950_13	1260251.SPISAL_07265	2.014e-07	61.0	COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1RYIB@1236|Gammaproteobacteria,1WW9G@135613|Chromatiales	135613|Chromatiales	J	Zinc-ribbon containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
CMS1_k127_2418950_2	580332.Slit_0314	5.955e-110	372.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
CMS1_k127_2418950_12	864051.BurJ1DRAFT_2911	3.291e-11	71.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_2418950_6	313606.M23134_07639	2.454e-89	308.0	COG0477@1|root,COG2814@2|Bacteria,4NHGU@976|Bacteroidetes	976|Bacteroidetes	EGP	Pfam Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_2418950_3	1126627.BAWE01000002_gene688	1.025e-107	355.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,3JREH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_40175	-	4.2.1.18,4.2.1.57	ko:K13766,ko:K13779	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R02085,R03493	RC00941,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_2418950_4	247490.KSU1_C0449	8.214e-101	346.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
CMS1_k127_2418950_10	1122604.JONR01000014_gene218	2.151e-16	82.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_2481874_2	1223521.BBJX01000005_gene2143	6.548e-70	246.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,4AA5A@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
CMS1_k127_2481874_1	323848.Nmul_A0682	1.781e-240	758.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,372IA@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2481874_4	748247.AZKH_4269	1.396e-63	225.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KV0G@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_2481874_0	522306.CAP2UW1_3464	3.113e-318	996.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
CMS1_k127_2481874_3	748247.AZKH_4267	6.638e-65	225.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VMHS@28216|Betaproteobacteria,2KUQ2@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2484376_16	1304883.KI912532_gene1639	1.042e-29	129.0	COG2165@1|root,COG2165@2|Bacteria,1N7CG@1224|Proteobacteria	1224|Proteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2484376_18	522306.CAP2UW1_0630	1.239e-15	89.0	2DTBA@1|root,33JIB@2|Bacteria,1NKRT@1224|Proteobacteria,2VY45@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2484376_19	1198452.Jab_2c02560	2.501e-14	84.0	2E6RE@1|root,331BH@2|Bacteria,1N8K0@1224|Proteobacteria,2VWUF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2484376_11	640081.Dsui_1391	6.891e-71	259.0	2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria,2KVNU@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2484376_3	1304883.KI912532_gene1643	1.482e-149	484.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KU71@206389|Rhodocyclales	206389|Rhodocyclales	NU	type II secretion system protein	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_2484376_0	1123487.KB892846_gene567	1.922e-240	755.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KUQA@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_2484376_15	640081.Dsui_1394	1.583e-48	191.0	COG3063@1|root,COG3063@2|Bacteria,1R1AG@1224|Proteobacteria,2WI0F@28216|Betaproteobacteria,2KZXT@206389|Rhodocyclales	206389|Rhodocyclales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2484376_2	1163617.SCD_n00573	2.375e-150	496.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II and III secretion system protein	exeD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
CMS1_k127_2484376_7	522306.CAP2UW1_0623	1.026e-107	364.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria	28216|Betaproteobacteria	U	AAA domain	exeA1	-	-	-	-	-	-	-	-	-	-	-	AAA_22,SPOR
CMS1_k127_2484376_1	1454004.AW11_03594	1.137e-154	505.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_2484376_12	1198452.Jab_2c02630	2.948e-69	257.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,477B7@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nosF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2484376_9	1485544.JQKP01000001_gene1099	3.132e-106	368.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,44VBC@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ABC transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_2484376_5	292415.Tbd_1899	1.008e-128	419.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,1KRYU@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS1_k127_2484376_13	1458357.BG58_24015	3.501e-59	221.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1K3MD@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_2484376_10	640081.Dsui_1401	2.634e-81	287.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,2KW45@206389|Rhodocyclales	206389|Rhodocyclales	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CMS1_k127_2484376_14	1121035.AUCH01000003_gene1185	6.628e-56	205.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KW7C@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS1_k127_2484376_20	228410.NE2380	2.56e-13	76.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2WB4V@28216|Betaproteobacteria,373NW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	transporter antisigma-factor antagonist STAS	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
CMS1_k127_2484376_6	757424.Hsero_4073	2.28e-118	398.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,472A9@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	ABC-type multidrug transport system, ATPase component	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2484376_8	1198452.Jab_1c00970	3.766e-107	357.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,472AY@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_2484376_17	1121004.ATVC01000003_gene482	2.475e-29	120.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS1_k127_2484376_4	1163617.SCD_n00584	7.556e-137	443.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_2735601_24	224911.27352622	8.696e-34	134.0	COG3686@1|root,COG3686@2|Bacteria,1RAEH@1224|Proteobacteria,2U5JJ@28211|Alphaproteobacteria,3JY5A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MAPEG family	MA20_30600	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_2735601_15	1234364.AMSF01000033_gene430	3.3e-69	242.0	COG1765@1|root,COG1765@2|Bacteria,1PHC3@1224|Proteobacteria,1TA7C@1236|Gammaproteobacteria,1X8WZ@135614|Xanthomonadales	135614|Xanthomonadales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_2735601_22	266264.Rmet_2691	5.175e-38	160.0	COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2VWNG@28216|Betaproteobacteria,1K6NB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_2735601_28	870187.Thini_2175	1.241e-16	92.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,45ZVX@72273|Thiotrichales	72273|Thiotrichales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CMS1_k127_2735601_2	713586.KB900536_gene1208	4.649e-180	608.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1WZX9@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_2735601_26	118163.Ple7327_1594	6.267e-27	130.0	COG2203@1|root,COG3437@1|root,COG3452@1|root,COG5000@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3452@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIKA@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_2735601_13	1123020.AUIE01000024_gene5075	2.761e-86	298.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RXE9@1236|Gammaproteobacteria,1YJ0W@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2735601_11	497321.C664_19351	2.233e-89	310.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2VPBZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2735601_9	1502852.FG94_00132	2.663e-100	343.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,478F6@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2735601_29	1121889.AUDM01000003_gene2338	3.247e-10	66.0	2EFT5@1|root,339J5@2|Bacteria,4NZGJ@976|Bacteroidetes,1I6IW@117743|Flavobacteriia,2NZDK@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2735601_16	1232410.KI421412_gene33	1.754e-68	236.0	COG0824@1|root,COG0824@2|Bacteria,1N4PH@1224|Proteobacteria,42V90@68525|delta/epsilon subdivisions,2X2K2@28221|Deltaproteobacteria,43VTS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
CMS1_k127_2735601_30	1123368.AUIS01000005_gene353	1.012e-08	63.0	28XT8@1|root,2ZJPP@2|Bacteria,1P53A@1224|Proteobacteria,1SVUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3330
CMS1_k127_2735601_0	323848.Nmul_A1542	9.989e-242	756.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2VKQG@28216|Betaproteobacteria,371QI@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_2735601_8	292415.Tbd_0236	3.254e-106	355.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS1_k127_2735601_25	266264.Rmet_1073	4.593e-33	148.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,1JZN6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS1_k127_2735601_17	640081.Dsui_2873	1.55e-62	219.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria,2KW89@206389|Rhodocyclales	206389|Rhodocyclales	O	Bacterial protein of unknown function (DUF899)	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_2735601_10	1123393.KB891328_gene626	5.733e-100	341.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,1KSMT@119069|Hydrogenophilales	119069|Hydrogenophilales	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
CMS1_k127_2735601_27	580332.Slit_2287	2.395e-26	117.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,44WH3@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2735601_12	1502770.JQMG01000001_gene401	3.761e-89	300.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,2KKWM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_2735601_14	305700.B447_00936	3.478e-84	303.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,2KUM7@206389|Rhodocyclales	206389|Rhodocyclales	M	(Lipo)protein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
CMS1_k127_2735601_3	62928.azo1096	4.174e-136	439.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KUG2@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_2735601_18	1121127.JAFA01000008_gene5891	3.927e-57	205.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,2VR4M@28216|Betaproteobacteria,1K2UH@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
CMS1_k127_2735601_4	85643.Tmz1t_1609	6.727e-133	435.0	COG2223@1|root,COG2223@2|Bacteria,1QU76@1224|Proteobacteria,2WGTH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Major facilitator Superfamily	yhjX_2	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2735601_7	1163617.SCD_n02166	4.602e-118	390.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_2735601_6	1173026.Glo7428_2590	4.577e-120	413.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS1_k127_2735601_19	365046.Rta_27530	1.315e-54	220.0	COG2230@1|root,COG2230@2|Bacteria,1QX5S@1224|Proteobacteria,2WHKW@28216|Betaproteobacteria,4AJZM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_2735601_1	1038859.AXAU01000015_gene937	1.477e-226	711.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVRF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_2735601_5	1038859.AXAU01000015_gene935	8.912e-124	404.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2UR9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_2735601_20	1298593.TOL_0587	4.899e-42	171.0	COG2067@1|root,COG2067@2|Bacteria,1QXG1@1224|Proteobacteria,1T3B4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
CMS1_k127_2735601_23	1265502.KB905929_gene2205	8.527e-36	138.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,4ACGG@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-binding enzyme	bclA_2	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2735951_9	338969.Rfer_2524	2.794e-91	308.0	COG0457@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria,4AE3D@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16,TPR_17
CMS1_k127_2735951_13	1123368.AUIS01000005_gene396	1.076e-23	110.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2735951_11	1487953.JMKF01000008_gene6044	9.828e-63	222.0	COG3803@1|root,COG3803@2|Bacteria,1G55K@1117|Cyanobacteria,1HAXI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
CMS1_k127_2735951_1	1415779.JOMH01000001_gene2583	1.245e-272	848.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1X4TP@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
CMS1_k127_2735951_6	228410.NE0105	6.935e-114	372.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,372K4@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_2735951_7	1123393.KB891316_gene1585	4.976e-97	343.0	COG0412@1|root,COG0412@2|Bacteria,1PDE6@1224|Proteobacteria,2VQWV@28216|Betaproteobacteria,1KSV3@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_2735951_0	1095769.CAHF01000007_gene1651	0.0	1273.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,472I0@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
CMS1_k127_2735951_10	1207063.P24_03825	8.283e-69	241.0	COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2TRBH@28211|Alphaproteobacteria,2JSI6@204441|Rhodospirillales	204441|Rhodospirillales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_2735951_2	1207063.P24_03835	8.471e-191	606.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,2JQ78@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_2735951_5	1007105.PT7_1573	1.868e-147	472.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_2735951_12	1207063.P24_03845	1.168e-37	150.0	COG3090@1|root,COG3090@2|Bacteria,1N0N7@1224|Proteobacteria,2U65H@28211|Alphaproteobacteria,2JX9C@204441|Rhodospirillales	204441|Rhodospirillales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_2735951_3	1007105.PT7_1571	1.18e-185	588.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_2735951_4	1100720.ALKN01000048_gene2365	1.705e-175	557.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJJD@28216|Betaproteobacteria,4ABX4@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_2735951_8	123899.JPQP01000001_gene1737	3.757e-93	323.0	COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,2VJB5@28216|Betaproteobacteria,3T9IX@506|Alcaligenaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_2781851_26	1163617.SCD_n03012	2.138e-44	168.0	COG3087@1|root,COG3087@2|Bacteria,1RIU5@1224|Proteobacteria,2VTKT@28216|Betaproteobacteria	28216|Betaproteobacteria	D	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_2781851_23	1000565.METUNv1_03311	1.34e-53	195.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,2KWSF@206389|Rhodocyclales	206389|Rhodocyclales	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
CMS1_k127_2781851_21	640081.Dsui_0676	6.625e-80	274.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,2KZNP@206389|Rhodocyclales	206389|Rhodocyclales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2781851_1	640081.Dsui_0971	5.656e-265	834.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KV59@206389|Rhodocyclales	206389|Rhodocyclales	I	poly(R)-hydroxyalkanoic acid synthase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
CMS1_k127_2781851_18	883126.HMPREF9710_00925	2.464e-114	379.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2VKJX@28216|Betaproteobacteria,4738J@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2781851_28	1031711.RSPO_c03126	7.911e-39	149.0	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,2VSPA@28216|Betaproteobacteria,1K6Y3@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	zntR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS1_k127_2781851_25	305700.B447_10842	6.694e-49	179.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2VRED@28216|Betaproteobacteria,2KYNZ@206389|Rhodocyclales	206389|Rhodocyclales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_2781851_3	1217720.ALOX01000032_gene194	1.177e-198	633.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,2JPCY@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2781851_27	1123261.AXDW01000005_gene2606	2.591e-39	153.0	COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,1T4J2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_2781851_4	93220.LV28_16380	7.015e-189	606.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1JZW5@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2781851_31	395493.BegalDRAFT_1907	1.938e-26	126.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	MA20_08885	-	-	ko:K17362	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT
CMS1_k127_2781851_9	1095769.CAHF01000005_gene1515	2.132e-160	516.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,473VB@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2781851_22	1121033.AUCF01000008_gene5677	3.921e-69	239.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VGB4@28211|Alphaproteobacteria,2JS51@204441|Rhodospirillales	204441|Rhodospirillales	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_2781851_24	1110502.TMO_1362	3.952e-49	182.0	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9DZ@28211|Alphaproteobacteria,2JSV6@204441|Rhodospirillales	204441|Rhodospirillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_2781851_20	1095769.CAHF01000005_gene1510	4.584e-89	307.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,4736H@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
CMS1_k127_2781851_11	748247.AZKH_0515	2.744e-141	455.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,2KUNG@206389|Rhodocyclales	206389|Rhodocyclales	E	HMGL-like	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS1_k127_2781851_35	1122614.JHZF01000016_gene495	4.223e-10	71.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2UJKX@28211|Alphaproteobacteria,2PEPD@252301|Oceanicola	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
CMS1_k127_2781851_29	1125863.JAFN01000001_gene972	4.904e-36	145.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS1_k127_2781851_8	395495.Lcho_3441	2.106e-160	520.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VHRJ@28216|Betaproteobacteria,1KKCG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	AMP-binding enzyme	paaK_2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_2781851_12	257310.BB0228	9.249e-139	445.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,3T2XB@506|Alcaligenaceae	28216|Betaproteobacteria	E	branched-chain amino acid	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_2781851_2	426114.THI_1095	1.498e-199	631.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2VI33@28216|Betaproteobacteria,1KJMC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2781851_7	1205680.CAKO01000040_gene773	5.7e-162	516.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT26@28211|Alphaproteobacteria,2JPYZ@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_2781851_15	1123367.C666_00590	1.287e-125	419.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2VIID@28216|Betaproteobacteria,2KVZ8@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2781851_14	477184.KYC_05686	1.038e-130	425.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJ0Q@28216|Betaproteobacteria,3T2Y1@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2781851_0	94624.Bpet4743	4.637e-284	887.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,3T1XK@506|Alcaligenaceae	28216|Betaproteobacteria	I	Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS1_k127_2781851_5	331869.BAL199_12941	3.141e-188	607.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2VFEC@28211|Alphaproteobacteria,4BQWR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2781851_19	488538.SAR116_1459	1.036e-105	361.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,4BREC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2781851_13	331869.BAL199_12931	1.771e-133	448.0	COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,2TVFT@28211|Alphaproteobacteria,4BRDF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2781851_17	1469245.JFBG01000052_gene2168	3.624e-118	391.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1X2CD@135613|Chromatiales	135613|Chromatiales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2781851_16	1469245.JFBG01000052_gene2167	3.148e-124	413.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Branched-chain amino acid transport	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_2781851_30	580332.Slit_0425	2.587e-34	142.0	2EEP1@1|root,338GU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2781851_34	196490.AUEZ01000043_gene6927	2.077e-11	66.0	2AF3S@1|root,3152G@2|Bacteria,1PV19@1224|Proteobacteria,2V4HP@28211|Alphaproteobacteria,3K5ND@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2781851_6	1205680.CAKO01000038_gene1597	6.987e-171	543.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2781851_33	485913.Krac_4615	5.674e-15	78.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_2781851_10	1123504.JQKD01000019_gene5540	7.131e-147	479.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2VHXE@28216|Betaproteobacteria,4ABHK@80864|Comamonadaceae	28216|Betaproteobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS1_k127_2809814_0	1454004.AW11_00371	0.0	1194.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_2809814_16	323261.Noc_1992	7.478e-50	203.0	COG0845@1|root,COG0845@2|Bacteria,1RG7M@1224|Proteobacteria,1S7F9@1236|Gammaproteobacteria,1X0V7@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS1_k127_2809814_6	1384054.N790_09605	1.4e-98	347.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria,1XA50@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS1_k127_2809814_11	1384056.N787_13645	3.055e-65	235.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,1RQBF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iECO103_1326.ECO103_2610,iYL1228.KPN_02573	Peptidase_S11
CMS1_k127_2809814_23	580332.Slit_2306	6.644e-20	102.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
CMS1_k127_2809814_7	1390370.O203_23385	1.091e-97	331.0	COG3386@1|root,COG3386@2|Bacteria,1P3IB@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS1_k127_2809814_13	1415778.JQMM01000001_gene2182	1.7e-59	218.0	COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP synthase gamma subunit	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS1_k127_2809814_2	1415778.JQMM01000001_gene2181	1.338e-215	691.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS1_k127_2809814_14	472759.Nhal_2237	7.51e-56	204.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,1R6C0@1224|Proteobacteria,1S4NA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
CMS1_k127_2809814_21	1131553.JIBI01000039_gene1940	2.173e-29	133.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,2VWUS@28216|Betaproteobacteria,373CH@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE-2	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS1_k127_2809814_9	1415778.JQMM01000001_gene2178	1.269e-90	303.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS1_k127_2809814_22	1288826.MSNKSG1_00546	8.647e-28	121.0	2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
CMS1_k127_2809814_18	1415778.JQMM01000001_gene2176	1.27e-32	146.0	COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	epsilon subunit	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CMS1_k127_2809814_1	1415778.JQMM01000001_gene2175	4.681e-235	734.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_2809814_25	1121935.AQXX01000135_gene3681	1.218e-05	54.0	2FDBS@1|root,345DK@2|Bacteria,1P196@1224|Proteobacteria,1SS3J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2809814_5	1048339.KB913029_gene3240	3.042e-119	389.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA5	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_2809814_26	1304883.KI912532_gene1319	0.0009062	51.0	COG0695@1|root,COG0695@2|Bacteria,1NGUN@1224|Proteobacteria,2VU88@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS1_k127_2809814_17	1384054.N790_04000	3.312e-36	152.0	2AQ4A@1|root,31F9J@2|Bacteria,1QCQH@1224|Proteobacteria,1T8GE@1236|Gammaproteobacteria,1XAMR@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2809814_4	331869.BAL199_22262	3.471e-167	531.0	COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2809814_24	313612.L8106_29165	5.836e-08	66.0	COG3210@1|root,COG3386@1|root,COG3210@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K11016	ko03070,map03070	-	-	-	ko00000,ko00001,ko02042,ko02044	-	-	-	CHU_C,DUF4347,Haemagg_act,HemolysinCabind
CMS1_k127_2809814_8	1054213.HMPREF9946_04782	6.255e-94	320.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,2JQIF@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
CMS1_k127_2809814_12	1408164.MOLA814_00378	1.25e-59	213.0	2BZNP@1|root,30717@2|Bacteria,1REWN@1224|Proteobacteria,2VRZH@28216|Betaproteobacteria,1KQZI@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
CMS1_k127_2809814_3	396588.Tgr7_1267	1.038e-198	640.0	COG0247@1|root,COG1145@1|root,COG0247@2|Bacteria,COG1145@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1WWK6@135613|Chromatiales	135613|Chromatiales	C	PFAM Cysteine-rich	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS1_k127_2809814_15	296591.Bpro_1187	2.909e-53	196.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,2VU6P@28216|Betaproteobacteria	28216|Betaproteobacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2809814_20	1209984.BN978_07498	2.34e-30	130.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria,238T5@1762|Mycobacteriaceae	201174|Actinobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_2809814_19	595537.Varpa_2356	2.823e-32	129.0	COG5470@1|root,COG5470@2|Bacteria,1N012@1224|Proteobacteria,2WFG0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_2918129_2	713586.KB900536_gene705	1.678e-89	297.0	COG1838@1|root,COG1838@2|Bacteria,1MVNG@1224|Proteobacteria,1RMT4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	)-tartrate dehydratase	ttdB	GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896	4.2.1.32	ko:K03780	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_2920	Fumerase_C
CMS1_k127_2918129_1	365046.Rta_33920	6.604e-153	489.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VH6G@28216|Betaproteobacteria,4ABRZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_2918129_0	1007105.PT7_2623	2.048e-315	979.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,3T6UJ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
CMS1_k127_2918839_9	113395.AXAI01000042_gene6040	7.925e-16	78.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JYHD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS1_k127_2918839_3	189753.AXAS01000012_gene4337	1.716e-61	226.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS1_k127_2918839_6	318996.AXAZ01000008_gene4295	7.958e-52	204.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS1_k127_2918839_4	864069.MicloDRAFT_00053230	1.282e-60	225.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria,1JRPJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_2918839_8	420324.KI911943_gene5242	5.482e-30	132.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,1JUDJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS1_k127_2918839_1	443598.AUFA01000039_gene5952	2.54e-127	436.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria,3JW2E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
CMS1_k127_2918839_7	395495.Lcho_0046	1.977e-30	128.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VVWD@28216|Betaproteobacteria,1KPCJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_2918839_5	189753.AXAS01000041_gene2534	1.746e-53	207.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS1_k127_2918839_0	395495.Lcho_0045	4.837e-132	431.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
CMS1_k127_2918839_10	318996.AXAZ01000131_gene3060	4.514e-09	64.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_2918839_2	113395.AXAI01000002_gene5247	1.543e-79	287.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Trans_reg_C
CMS1_k127_2934443_2	1168065.DOK_01329	2.647e-73	265.0	COG4872@1|root,COG4872@2|Bacteria,1NAIX@1224|Proteobacteria,1S1XV@1236|Gammaproteobacteria,1J9Q3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS1_k127_2934443_4	1408164.MOLA814_01668	4.573e-62	216.0	2DMP1@1|root,32SS8@2|Bacteria,1MZTD@1224|Proteobacteria,2WG6B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
CMS1_k127_2934443_0	1232410.KI421426_gene1381	4.192e-196	621.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS1_k127_2934443_1	1454004.AW11_03184	4.41e-96	329.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,2VNAW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2934443_6	522306.CAP2UW1_2137	3.247e-12	70.0	COG4309@1|root,COG4309@2|Bacteria,1NHRT@1224|Proteobacteria,2VXM5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
CMS1_k127_2934443_5	62928.azo3087	6.178e-43	163.0	COG3945@1|root,COG3945@2|Bacteria,1N383@1224|Proteobacteria,2VUXI@28216|Betaproteobacteria,2KZW9@206389|Rhodocyclales	206389|Rhodocyclales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS1_k127_2934443_3	225849.swp_0274	1.097e-68	245.0	2910Q@1|root,2ZNNC@2|Bacteria,1PCP3@1224|Proteobacteria,1S0BX@1236|Gammaproteobacteria,2Q953@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2988680_15	580332.Slit_2885	1.688e-65	239.0	COG1216@1|root,COG1216@2|Bacteria,1NG6M@1224|Proteobacteria,2VQVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_transf_21,Glyco_transf_7C,Glycos_transf_2
CMS1_k127_2988680_13	580332.Slit_2886	2.219e-77	270.0	COG0463@1|root,COG0463@2|Bacteria,1N635@1224|Proteobacteria,2VWIY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2988680_12	1485544.JQKP01000001_gene1330	5.633e-86	301.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,44VGA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS1_k127_2988680_14	1499686.BN1079_02328	1.44e-76	276.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS1_k127_2988680_6	1165096.ARWF01000001_gene187	4.019e-147	471.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,2KM7G@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_2988680_4	1163617.SCD_n02913	6.8e-172	545.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_2988680_9	342113.DM82_545	3.566e-117	391.0	COG0859@1|root,COG0859@2|Bacteria,1PMNX@1224|Proteobacteria,2VPUG@28216|Betaproteobacteria,1K3ZM@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CMS1_k127_2988680_8	1163617.SCD_n02864	2.841e-118	416.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2988680_1	1163617.SCD_n02863	6.004e-222	706.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2988680_10	243365.CV_0817	3.236e-97	357.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,2VJET@28216|Betaproteobacteria,2KQU0@206351|Neisseriales	206351|Neisseriales	M	Glycosyltransferase Family 4	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2988680_7	1163617.SCD_n02861	6.871e-132	430.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VRSM@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 9	rfaQ	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_2988680_3	1485544.JQKP01000002_gene1357	2.918e-201	649.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,2WGMC@28216|Betaproteobacteria,44V6B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_2988680_11	1000565.METUNv1_03348	5.577e-88	299.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_2988680_18	545264.KB898757_gene2464	9.653e-13	72.0	2CFFZ@1|root,34BFH@2|Bacteria,1P1YF@1224|Proteobacteria,1SRW1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2988680_19	1454004.AW11_02158	3.932e-10	62.0	2EG8X@1|root,33A0Q@2|Bacteria,1NMVN@1224|Proteobacteria,2VY0V@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2988680_17	582744.Msip34_0158	4.55e-33	132.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria,2KP3R@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS1_k127_2988680_16	596153.Alide_2241	4.659e-61	217.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,4AE5E@80864|Comamonadaceae	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS1_k127_2988680_5	292415.Tbd_2779	3.461e-160	515.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,1KRCZ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2988680_2	1121035.AUCH01000008_gene994	2.143e-216	695.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,2KVAV@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
CMS1_k127_2988680_0	159087.Daro_3866	3.355e-222	702.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,2KUXG@206389|Rhodocyclales	206389|Rhodocyclales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS1_k127_2988680_20	1121035.AUCH01000006_gene629	3.735e-06	52.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,2KWVJ@206389|Rhodocyclales	206389|Rhodocyclales	D	cell division protein	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_3034164_5	1207076.ALAT01000168_gene3756	1.028e-16	79.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1Z22G@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_3034164_4	497321.C664_09060	4.411e-38	147.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,2VUEX@28216|Betaproteobacteria,2KYSM@206389|Rhodocyclales	206389|Rhodocyclales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS1_k127_3034164_1	640081.Dsui_0371	2.438e-94	321.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2VKUA@28216|Betaproteobacteria,2KUIE@206389|Rhodocyclales	206389|Rhodocyclales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_3034164_2	1095769.CAHF01000004_gene2753	8.365e-75	252.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2VPZW@28216|Betaproteobacteria,47449@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS1_k127_3034164_0	323848.Nmul_A0756	3.764e-104	342.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2VHDK@28216|Betaproteobacteria,371RB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_3034164_3	1123354.AUDR01000005_gene1592	3.888e-65	226.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2VQ7A@28216|Betaproteobacteria,1KRMM@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS1_k127_3034164_6	1000565.METUNv1_02255	1.779e-12	67.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,2KWTF@206389|Rhodocyclales	206389|Rhodocyclales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS1_k127_3036240_0	887898.HMPREF0551_0747	6.401e-237	748.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,1K0BK@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_3036240_3	1244869.H261_21029	1.701e-62	219.0	COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2U6JY@28211|Alphaproteobacteria,2JTDY@204441|Rhodospirillales	204441|Rhodospirillales	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_3036240_2	159087.Daro_0595	5.714e-93	308.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,2KUQ0@206389|Rhodocyclales	206389|Rhodocyclales	H	Molybdenum cofactor biosynthesis protein	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS1_k127_3036240_4	713587.THITH_13835	5.231e-40	154.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1WY21@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
CMS1_k127_3036240_1	323848.Nmul_A2415	1.333e-172	552.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,37276@32003|Nitrosomonadales	28216|Betaproteobacteria	L	modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_3036240_5	1411123.JQNH01000001_gene1722	8.376e-18	83.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_3066433_1	1038862.KB893829_gene5036	1.037e-150	484.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TT8C@28211|Alphaproteobacteria,3JXM0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_3066433_2	1038860.AXAP01000089_gene3712	4.472e-118	404.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3JWN0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_3066433_0	1380394.JADL01000004_gene5935	2.519e-164	527.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria,2JR5U@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_3066433_3	1187851.A33M_2606	2.259e-57	204.0	COG0559@1|root,COG0559@2|Bacteria,1R5JM@1224|Proteobacteria,2TUSY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_3067674_3	502025.Hoch_0043	1.412e-71	259.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,42N6J@68525|delta/epsilon subdivisions,2WJ0W@28221|Deltaproteobacteria,2Z08Y@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3067674_4	1458357.BG58_33535	3.065e-54	205.0	COG0596@1|root,COG0596@2|Bacteria,1NCX0@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3067674_1	709797.CSIRO_3898	3.16e-118	392.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,1QTZ6@1224|Proteobacteria,2TWKD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS1_k127_3067674_5	2340.JV46_22860	1.958e-34	137.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1J7BB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
CMS1_k127_3067674_8	1247649.D560_2409	8.201e-08	63.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VHP1@28216|Betaproteobacteria,3T6RQ@506|Alcaligenaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE1	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
CMS1_k127_3067674_6	196162.Noca_2118	3.036e-19	94.0	COG4244@1|root,COG4244@2|Bacteria,2II9W@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
CMS1_k127_3067674_7	1163407.UU7_03617	1.733e-14	78.0	2ECSH@1|root,32CA7@2|Bacteria,1PW3Z@1224|Proteobacteria,1RW51@1236|Gammaproteobacteria,1X831@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3067674_2	1095769.CAHF01000005_gene1543	2.761e-75	274.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VR5K@28216|Betaproteobacteria,4748K@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3067674_0	748247.AZKH_2015	6.341e-189	599.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2VVJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_3097554_9	1163617.SCD_n01293	8.691e-106	350.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS1_k127_3097554_12	153948.NAL212_2508	4.784e-63	235.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,372TT@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_3097554_18	190650.CC_2380	1.857e-05	47.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS1_k127_3097554_13	580332.Slit_2945	4.085e-57	205.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,2VX84@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS1_k127_3097554_14	580332.Slit_2946	6.072e-40	154.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,2VW0N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_3097554_15	1532557.JL37_19045	4.682e-38	161.0	COG0599@1|root,COG0599@2|Bacteria,1R9MY@1224|Proteobacteria,2W2D8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_3097554_2	795666.MW7_2356	5.693e-231	738.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2W150@28216|Betaproteobacteria,1KCF8@119060|Burkholderiaceae	28216|Betaproteobacteria	E	GMC oxidoreductase	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_3097554_0	795666.MW7_2355	1.396e-248	788.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,1K2XV@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_3097554_10	1095769.CAHF01000011_gene2117	2.608e-87	298.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2VIUS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153,4.2.1.56	ko:K09709,ko:K18291	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R02491,R09282	RC00730,RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N
CMS1_k127_3097554_11	1007105.PT7_3043	8.5e-74	255.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2VI58@28216|Betaproteobacteria,3T44B@506|Alcaligenaceae	28216|Betaproteobacteria	K	FCD	mcbR_2	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_3097554_5	1007105.PT7_3033	3.42e-157	510.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2W1IE@28216|Betaproteobacteria,3T1DH@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_3097554_3	1007105.PT7_3034	1.662e-216	689.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,3T1XI@506|Alcaligenaceae	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_3097554_4	93220.LV28_12100	2.345e-158	532.0	COG0439@1|root,COG0439@2|Bacteria,1R7YR@1224|Proteobacteria,2VIIZ@28216|Betaproteobacteria,1KBK5@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS1_k127_3097554_16	471852.Tcur_3702	4.912e-15	77.0	COG0511@1|root,COG0511@2|Bacteria,2I56V@201174|Actinobacteria	201174|Actinobacteria	I	Biotin-lipoyl like	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS1_k127_3097554_1	1007105.PT7_3036	1.452e-231	727.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,3T5HE@506|Alcaligenaceae	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_3097554_6	1007105.PT7_3044	7.233e-130	443.0	COG0715@1|root,COG0715@2|Bacteria,1MWJF@1224|Proteobacteria,2VKCQ@28216|Betaproteobacteria,3T92X@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
CMS1_k127_3097554_7	94624.Bpet0412	4.561e-126	410.0	COG1116@1|root,COG1116@2|Bacteria,1MUYG@1224|Proteobacteria,2VHDU@28216|Betaproteobacteria,3T2MF@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS1_k127_3097554_8	1007105.PT7_3046	2.069e-116	381.0	COG0600@1|root,COG0600@2|Bacteria,1PC26@1224|Proteobacteria,2VJ97@28216|Betaproteobacteria,3T3G2@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_3149211_34	1131553.JIBI01000004_gene396	1.083e-91	308.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,2VZB8@28216|Betaproteobacteria,372HT@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
CMS1_k127_3149211_42	869210.Marky_0498	3.513e-78	278.0	COG1893@1|root,COG1893@2|Bacteria,1WMJG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_3149211_22	869210.Marky_0497	8.706e-120	408.0	COG0413@1|root,COG0413@2|Bacteria,1WIJJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS1_k127_3149211_21	1500890.JQNL01000001_gene1641	8.691e-120	401.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1X416@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
CMS1_k127_3149211_37	1123354.AUDR01000013_gene591	1.538e-82	284.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,1KRK0@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS1_k127_3149211_20	1454004.AW11_00156	3.765e-120	399.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,1KPXM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
CMS1_k127_3149211_46	1000565.METUNv1_03628	6.737e-65	243.0	28TB7@1|root,2ZFJR@2|Bacteria,1PACM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3149211_29	1411123.JQNH01000001_gene964	5.85e-96	318.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	MA20_22025	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS1_k127_3149211_70	1095769.CAHF01000005_gene1437	4.942e-15	77.0	2EITT@1|root,33CJ3@2|Bacteria,1NH36@1224|Proteobacteria,2VXT6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS1_k127_3149211_44	522306.CAP2UW1_3877	4.074e-69	252.0	COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,2VITZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C13
CMS1_k127_3149211_24	1123393.KB891316_gene1686	2.012e-109	371.0	COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease,HD,PolyA_pol,PolyA_pol_RNAbd
CMS1_k127_3149211_41	1123393.KB891316_gene2019	1.52e-78	268.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_4,GST_N_3
CMS1_k127_3149211_31	305700.B447_11017	5.301e-94	319.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,2KUXF@206389|Rhodocyclales	206389|Rhodocyclales	GM	epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_3149211_15	1163617.SCD_n00396	1.691e-153	506.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
CMS1_k127_3149211_36	748247.AZKH_2782	6.185e-90	323.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,2VJPB@28216|Betaproteobacteria,2KZQ9@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD
CMS1_k127_3149211_6	748247.AZKH_2783	5.735e-214	691.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVQ2@206389|Rhodocyclales	206389|Rhodocyclales	T	Response regulator receiver modulated diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
CMS1_k127_3149211_4	1163617.SCD_n00393	1.033e-232	739.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS1_k127_3149211_62	748247.AZKH_4343	2.339e-36	141.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria,2KWWC@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3149211_3	1038860.AXAP01000008_gene5969	2.044e-261	812.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2UQJ2@28211|Alphaproteobacteria,3K2BQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	HpaB,HpaB_N
CMS1_k127_3149211_52	153948.NAL212_1047	3.87e-51	202.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,2VSA7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3149211_35	1163617.SCD_n01147	1.679e-91	328.0	COG2202@1|root,COG3452@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3452@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WGSC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
CMS1_k127_3149211_18	62928.azo1028	2.045e-136	438.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VGZU@28216|Betaproteobacteria,2KVXF@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	hbdA	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS1_k127_3149211_2	85643.Tmz1t_1204	2.681e-302	943.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,2KV7T@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_3149211_1	62928.azo3215	0.0	1250.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KV8K@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_3149211_61	1288494.EBAPG3_5100	2.698e-39	154.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,3738A@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
CMS1_k127_3149211_27	640512.BC1003_2958	1.43e-102	351.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,1K2MD@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
CMS1_k127_3149211_12	228410.NE2158	2.05e-178	567.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,372F1@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_3149211_51	1000565.METUNv1_02990	2.398e-53	204.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,2KW3W@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_3149211_59	272560.BPSL1161	4.534e-42	159.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,1K6ZB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS1_k127_3149211_58	640081.Dsui_0451	6.54e-43	168.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,2KWIS@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CMS1_k127_3149211_49	1163617.SCD_n00061	3.419e-62	222.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_3149211_5	522306.CAP2UW1_0537	6.779e-231	728.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,1KPMZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Translation, ribosomal structure and biogenesis	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS1_k127_3149211_13	479434.Sthe_3255	9.525e-178	589.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_3149211_39	316057.RPD_1510	4.615e-80	271.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2UE39@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	-	-	1.2.1.58,1.2.7.1	ko:K00172,ko:K18357	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS1_k127_3149211_57	316057.RPD_1511	1.309e-43	170.0	COG1144@1|root,COG1144@2|Bacteria,1N5VK@1224|Proteobacteria,2UVED@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S binding domain	-	-	1.2.1.58	ko:K18358	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4
CMS1_k127_3149211_11	748247.AZKH_2899	6.317e-194	621.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,2KVEF@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate:ferredoxin oxidoreductase core domain II	padG	-	1.2.1.58	ko:K18355	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	PFOR_II,POR_N
CMS1_k127_3149211_16	76114.ebA5400	1.559e-139	473.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VN52@28216|Betaproteobacteria,2KV2K@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyridine nucleotide-disulphide oxidoreductase	padH	-	1.2.1.58	ko:K18359	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_3149211_7	76114.ebA5401	2.095e-212	667.0	COG0437@1|root,COG1013@1|root,COG0437@2|Bacteria,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,2KVZU@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	padI	-	1.2.1.58	ko:K18356	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4_11,Fer4_6,TPP_enzyme_C
CMS1_k127_3149211_9	395494.Galf_0664	2.765e-203	660.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VNC@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_3149211_32	648757.Rvan_3586	3.612e-93	311.0	COG4887@1|root,COG4887@2|Bacteria,1RKM1@1224|Proteobacteria,2U481@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1847
CMS1_k127_3149211_71	316055.RPE_3064	8.136e-15	88.0	2E0AX@1|root,32VY8@2|Bacteria,1N21Q@1224|Proteobacteria,2UECC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS1_k127_3149211_56	187272.Mlg_0226	1.382e-44	166.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria,1X0YM@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulator, Rrf2 family	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
CMS1_k127_3149211_63	443143.GM18_3005	1.334e-33	136.0	COG3945@1|root,COG3945@2|Bacteria,1NG3G@1224|Proteobacteria,42WHU@68525|delta/epsilon subdivisions,2WRK5@28221|Deltaproteobacteria,43UTP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS1_k127_3149211_64	1137799.GZ78_21580	3.55e-33	135.0	2E4R1@1|root,32ZJK@2|Bacteria,1N8FZ@1224|Proteobacteria,1SAJ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nitrous oxide-stimulated promoter	ygbA	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
CMS1_k127_3149211_38	1000565.METUNv1_02459	3.543e-80	291.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VX93@28216|Betaproteobacteria,2KXPI@206389|Rhodocyclales	206389|Rhodocyclales	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
CMS1_k127_3149211_17	748247.AZKH_0348	1.995e-138	454.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VNUX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_3149211_50	748247.AZKH_0347	9.107e-54	199.0	COG3303@1|root,COG3303@2|Bacteria,1RG2D@1224|Proteobacteria,2VRXP@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS1_k127_3149211_48	395495.Lcho_4133	1.32e-62	228.0	COG0760@1|root,COG0760@2|Bacteria,1RGNX@1224|Proteobacteria,2VRQU@28216|Betaproteobacteria,1KNFK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N_3
CMS1_k127_3149211_45	395495.Lcho_4132	2.93e-68	260.0	2CBTM@1|root,32RU1@2|Bacteria,1N3GE@1224|Proteobacteria,2VURB@28216|Betaproteobacteria,1KNM9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3149211_55	748247.AZKH_0334	2.455e-45	169.0	COG3245@1|root,COG3245@2|Bacteria,1RG2V@1224|Proteobacteria,2VS0Q@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS1_k127_3149211_47	864051.BurJ1DRAFT_4168	7.616e-64	226.0	COG3245@1|root,COG3245@2|Bacteria,1RCEB@1224|Proteobacteria,2VQIB@28216|Betaproteobacteria,1KNAQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3
CMS1_k127_3149211_53	748247.AZKH_0343	8.947e-49	190.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria,2VTRB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS1_k127_3149211_54	395495.Lcho_4126	8.733e-46	179.0	2DVIY@1|root,33W46@2|Bacteria,1MYRQ@1224|Proteobacteria,2VTQY@28216|Betaproteobacteria,1KNMN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS1_k127_3149211_65	748247.AZKH_0341	1.559e-32	140.0	28YFG@1|root,2ZK9T@2|Bacteria,1P4D4@1224|Proteobacteria,2W5P9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3149211_28	395495.Lcho_4124	7.912e-102	350.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,2WEWP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_3149211_43	880073.Calab_1263	3.524e-73	272.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS1_k127_3149211_73	105425.BBPL01000075_gene3862	1.291e-06	62.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,2NEXR@228398|Streptacidiphilus	201174|Actinobacteria	O	ResB-like family	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS1_k127_3149211_72	1051006.HMPREF1162_1729	2.584e-12	79.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4DN12@85009|Propionibacteriales	201174|Actinobacteria	O	ResB-like family	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS1_k127_3149211_67	316067.Geob_0056	3.172e-29	130.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WIKV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_3149211_60	316067.Geob_3344	8.373e-42	171.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_3149211_66	635013.TherJR_1028	2.145e-30	133.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_3149211_10	443144.GM21_3552	1.981e-196	631.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS1_k127_3149211_68	395495.Lcho_4116	3.249e-27	113.0	COG2010@1|root,COG2010@2|Bacteria,1NATR@1224|Proteobacteria,2VXA9@28216|Betaproteobacteria,1KP7S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_3149211_40	880526.KE386488_gene1053	6.003e-79	276.0	COG2267@1|root,COG2267@2|Bacteria,4NHI2@976|Bacteroidetes,2FNPW@200643|Bacteroidia,22V0W@171550|Rikenellaceae	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_3149211_0	1454004.AW11_00344	0.0	1277.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,1KQ6G@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
CMS1_k127_3149211_14	1265502.KB905932_gene1798	4.937e-161	513.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VH6G@28216|Betaproteobacteria,4ABRZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_3149211_8	1380394.JADL01000014_gene184	3.033e-208	655.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2JQ2W@204441|Rhodospirillales	204441|Rhodospirillales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_3149211_23	1502852.FG94_04591	5.335e-111	379.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,472VU@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	methyl-accepting chemotaxis protein	tar3	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
CMS1_k127_3149211_30	1245469.S58_30020	1.044e-95	316.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,3JSMD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	MA20_26500	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_3149211_25	522306.CAP2UW1_2839	1.329e-107	358.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria,1KQIA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	clcD	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS1_k127_3149211_26	1123366.TH3_13045	3.893e-105	364.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,2JR2J@204441|Rhodospirillales	204441|Rhodospirillales	G	transport system permease	-	-	-	ko:K02026,ko:K05815,ko:K10238	ko02010,map02010	M00198,M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_3149211_19	670292.JH26_14805	7.798e-122	406.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TSH3@28211|Alphaproteobacteria,1JX14@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	thuF	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
CMS1_k127_3149211_33	1190603.AJYD01000015_gene947	1.063e-91	306.0	COG1653@1|root,COG1653@2|Bacteria,1MX9J@1224|Proteobacteria,1RPYT@1236|Gammaproteobacteria,1XUUS@135623|Vibrionales	135623|Vibrionales	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10236	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	SBP_bac_1
CMS1_k127_3170718_2	1288494.EBAPG3_25810	1.436e-90	301.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,371V5@32003|Nitrosomonadales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
CMS1_k127_3170718_3	640081.Dsui_1899	3.316e-90	312.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,2KV2Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_3170718_6	85643.Tmz1t_3669	7.046e-57	201.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,2KWGN@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS1_k127_3170718_9	1163617.SCD_n01791	1.686e-19	93.0	COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
CMS1_k127_3170718_7	748247.AZKH_0653	2.754e-37	142.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,2KWXF@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS1_k127_3170718_5	62928.azo0721	3.063e-58	207.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,2KWBY@206389|Rhodocyclales	206389|Rhodocyclales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS1_k127_3170718_1	1288494.EBAPG3_25740	2.057e-197	628.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,372T4@32003|Nitrosomonadales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS1_k127_3170718_8	472759.Nhal_2660	2.376e-30	138.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CMS1_k127_3170718_0	76114.ebA4946	9.532e-231	723.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,2KUNN@206389|Rhodocyclales	206389|Rhodocyclales	T	ATPase related to phosphate starvation-inducible protein PhoH	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CMS1_k127_3170718_4	76114.ebA4948	5.306e-65	225.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,2KWEZ@206389|Rhodocyclales	206389|Rhodocyclales	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_320662_1	1123228.AUIH01000001_gene1323	2.07e-151	490.0	COG2358@1|root,COG2358@2|Bacteria,1R9PA@1224|Proteobacteria,1SQQW@1236|Gammaproteobacteria,1XPPG@135619|Oceanospirillales	135619|Oceanospirillales	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_320662_0	1123228.AUIH01000001_gene1322	1.308e-275	864.0	COG4666@1|root,COG4666@2|Bacteria,1R58Z@1224|Proteobacteria,1SN2T@1236|Gammaproteobacteria,1XN7E@135619|Oceanospirillales	135619|Oceanospirillales	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_320662_3	1380394.JADL01000008_gene3447	4.649e-120	393.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TUWV@28211|Alphaproteobacteria,2JQWC@204441|Rhodospirillales	204441|Rhodospirillales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_320662_4	269799.Gmet_0914	5.477e-45	168.0	2ED7H@1|root,33743@2|Bacteria,1QB7X@1224|Proteobacteria,42ZXA@68525|delta/epsilon subdivisions,2WVEQ@28221|Deltaproteobacteria,43V94@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_320662_2	1231391.AMZF01000008_gene1571	3.826e-149	479.0	COG3485@1|root,COG3485@2|Bacteria,1QBMH@1224|Proteobacteria,2VJPE@28216|Betaproteobacteria,3T427@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Catechol dioxygenase N terminus	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
CMS1_k127_3223858_66	909663.KI867150_gene69	6.53e-48	181.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3223858_64	1121127.JAFA01000033_gene4544	1.947e-50	188.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,1K9IT@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_3223858_34	296591.Bpro_4318	3.116e-99	332.0	COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,2VHKB@28216|Betaproteobacteria,4ABGT@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K19338	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3223858_14	365044.Pnap_2033	4.156e-193	609.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2VJAW@28216|Betaproteobacteria,4ACNS@80864|Comamonadaceae	28216|Betaproteobacteria	S	PrpF protein	fldA	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
CMS1_k127_3223858_13	62928.azo2542	1.238e-213	665.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,2VIM3@28216|Betaproteobacteria,2KXPR@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS1_k127_3223858_16	497321.C664_11490	1.151e-186	584.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2VIDM@28216|Betaproteobacteria,2KX5F@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	-	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS1_k127_3223858_51	864051.BurJ1DRAFT_2573	9.138e-70	237.0	COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,2VQ2B@28216|Betaproteobacteria,1KKQH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	1.13.11.8	ko:K04100	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA
CMS1_k127_3223858_21	365046.Rta_24760	1.368e-154	491.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VI4U@28216|Betaproteobacteria,4AA2I@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protocatechuate 4,5-dioxygenase	ligB	-	1.13.11.57,1.13.11.8	ko:K04099,ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA,LigB
CMS1_k127_3223858_19	652103.Rpdx1_4878	1.369e-169	537.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2TV6R@28211|Alphaproteobacteria,3JWGS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	ligC	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3223858_35	296591.Bpro_1741	4.137e-99	353.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
CMS1_k127_3223858_76	2340.JV46_16940	0.0004253	53.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.2.7.1	ko:K03737,ko:K05337	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_3223858_39	1187851.A33M_4209	1.223e-95	341.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_3223858_36	1049564.TevJSym_bb00040	2.324e-98	355.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_3223858_12	1049564.TevJSym_bb00050	9.823e-222	715.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS1_k127_3223858_9	1187851.A33M_4208	5.528e-241	756.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
CMS1_k127_3223858_22	1187851.A33M_4207	2.035e-152	486.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	gltA	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2
CMS1_k127_3223858_2	314345.SPV1_00345	1.365e-301	951.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria	1224|Proteobacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS1_k127_3223858_29	706587.Desti_1948	4.276e-122	424.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
CMS1_k127_3223858_63	1278309.KB907101_gene517	1.062e-51	194.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,1SZTB@1236|Gammaproteobacteria,1XRNY@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3223858_60	522306.CAP2UW1_3364	5.504e-56	206.0	COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,2VT03@28216|Betaproteobacteria	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_3223858_44	1357279.N018_05030	1.344e-85	304.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,1Z9CW@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CMS1_k127_3223858_48	522306.CAP2UW1_3395	2.42e-71	263.0	28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,2VSQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS1_k127_3223858_68	522306.CAP2UW1_3394	6.002e-45	180.0	COG3064@1|root,COG3064@2|Bacteria,1PUUY@1224|Proteobacteria,2VXQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
CMS1_k127_3223858_26	1120999.JONM01000010_gene4131	5.971e-130	426.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,2KQTD@206351|Neisseriales	206351|Neisseriales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_3223858_31	1123399.AQVE01000002_gene2297	5.174e-115	389.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_3223858_47	365046.Rta_14950	1.057e-72	260.0	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria	1224|Proteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3223858_25	365046.Rta_14960	2.252e-133	441.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3223858_42	452637.Oter_3786	4.699e-89	319.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_3223858_5	640081.Dsui_2996	1.587e-288	896.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KV9Y@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS1_k127_3223858_17	1266925.JHVX01000022_gene1763	3.1e-173	554.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria,372VG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS1_k127_3223858_67	1379698.RBG1_1C00001G0244	7.073e-46	180.0	COG1764@1|root,COG1764@2|Bacteria,2NQ0N@2323|unclassified Bacteria	2|Bacteria	O	OsmC-like protein	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
CMS1_k127_3223858_55	1123355.JHYO01000011_gene1419	6.958e-66	229.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,36YEB@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Redoxin	MA20_20905	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
CMS1_k127_3223858_32	383372.Rcas_3448	9.141e-107	355.0	COG0123@1|root,COG0123@2|Bacteria,2G89I@200795|Chloroflexi,376ST@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_3223858_62	316274.Haur_0092	3.716e-52	192.0	COG1296@1|root,COG1296@2|Bacteria,2G6SG@200795|Chloroflexi	200795|Chloroflexi	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
CMS1_k127_3223858_74	402881.Plav_1961	6.282e-14	75.0	COG4392@1|root,COG4392@2|Bacteria,1MZUZ@1224|Proteobacteria,2UC31@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
CMS1_k127_3223858_6	378806.STAUR_8390	7.726e-272	863.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YWH3@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_3223858_52	261292.Nit79A3_3088	1.467e-69	240.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,372GF@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_3223858_65	640081.Dsui_2669	4.354e-50	189.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5,DUF4274
CMS1_k127_3223858_0	1454004.AW11_03443	0.0	1480.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,1KR73@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_3223858_59	1005048.CFU_1606	7.667e-57	204.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,4729H@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS1_k127_3223858_18	1163617.SCD_n00952	9.278e-171	552.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS1_k127_3223858_8	497321.C664_02845	2.453e-247	770.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS1_k127_3223858_4	1288494.EBAPG3_21520	1.034e-294	916.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,371N6@32003|Nitrosomonadales	28216|Betaproteobacteria	C	chain 5 L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CMS1_k127_3223858_69	426114.THI_2629	2.054e-43	160.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,1KM2T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS1_k127_3223858_49	292415.Tbd_1151	2.63e-71	246.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KS7Z@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS1_k127_3223858_43	1288494.EBAPG3_21480	3.301e-88	293.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,371MN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS1_k127_3223858_20	381666.H16_A1057	3.319e-167	531.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,1K1ZY@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS1_k127_3223858_3	580332.Slit_1076	6.785e-295	944.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,44UZF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS1_k127_3223858_11	1123354.AUDR01000018_gene1153	1.09e-237	747.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,1KS1J@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_3223858_54	228410.NE1773	4.091e-67	250.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,371SU@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS1_k127_3223858_10	1144319.PMI16_03532	1.292e-239	743.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,4737P@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS1_k127_3223858_41	1218075.BAYA01000026_gene5475	1.249e-90	308.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS1_k127_3223858_40	1123393.KB891327_gene377	7.258e-94	308.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,1KSD5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS1_k127_3223858_61	1288494.EBAPG3_21400	3.605e-55	195.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,3737D@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS1_k127_3223858_72	159087.Daro_0948	1.543e-31	129.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,2KWZZ@206389|Rhodocyclales	206389|Rhodocyclales	U	preprotein translocase	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS1_k127_3223858_38	323848.Nmul_A1089	9.945e-96	319.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,371NW@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS1_k127_3223858_53	1163617.SCD_n02070	9.325e-69	242.0	COG0500@1|root,COG2226@2|Bacteria,1NRR4@1224|Proteobacteria,2W05F@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS1_k127_3223858_73	1238182.C882_4201	1.069e-22	107.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2UI14@28211|Alphaproteobacteria,2JUB3@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase subunit D	-	-	-	-	-	-	-	-	-	-	-	-	Fumarate_red_D
CMS1_k127_3223858_71	1238182.C882_4200	1.197e-33	139.0	COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,2UFZX@28211|Alphaproteobacteria,2JUG8@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase subunit C	-	-	-	-	-	-	-	-	-	-	-	-	Fumarate_red_C
CMS1_k127_3223858_33	1238182.C882_4199	2.111e-99	349.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U3AH@28211|Alphaproteobacteria,2JRIM@204441|Rhodospirillales	204441|Rhodospirillales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_3,Fer4_8
CMS1_k127_3223858_7	1150626.PHAMO_570076	3.795e-256	801.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U0QC@28211|Alphaproteobacteria,2JQ41@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_3223858_45	1454004.AW11_02934	2.728e-84	297.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,1KQB8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16
CMS1_k127_3223858_70	1288494.EBAPG3_12750	4.139e-39	153.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,37311@32003|Nitrosomonadales	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS1_k127_3223858_50	335283.Neut_1637	7.613e-71	269.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,372UU@32003|Nitrosomonadales	28216|Betaproteobacteria	CO	oxidoreductase DsbE	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_3223858_1	1485544.JQKP01000007_gene1989	4.352e-305	957.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,44VEM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS1_k127_3223858_57	1288494.EBAPG3_12780	3.864e-59	213.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CMS1_k127_3223858_75	1000565.METUNv1_01599	2.811e-07	61.0	COG3114@1|root,COG3114@2|Bacteria	2|Bacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
CMS1_k127_3223858_30	305700.B447_01996	4.502e-118	386.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,2KV1K@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS1_k127_3223858_46	365044.Pnap_0588	1.309e-82	280.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,4ADQT@80864|Comamonadaceae	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CMS1_k127_3223858_58	640081.Dsui_1167	1.822e-58	210.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,2KW6J@206389|Rhodocyclales	206389|Rhodocyclales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CMS1_k127_3223858_56	640081.Dsui_1460	2.164e-64	227.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,2KVHP@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_3223858_27	1156919.QWC_04823	5.306e-128	429.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,3T1WB@506|Alcaligenaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS1_k127_3223858_28	1437824.BN940_04486	1.348e-127	415.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,3T1E5@506|Alcaligenaceae	28216|Betaproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS1_k127_3223858_24	257310.BB1467	1.085e-134	436.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,3T2SF@506|Alcaligenaceae	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS1_k127_3223858_23	1163617.SCD_n00932	1.594e-144	467.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_3223858_15	640081.Dsui_3057	1.937e-188	601.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,2KUMC@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_3223858_37	580332.Slit_1062	5.33e-98	327.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,44V46@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS1_k127_3327808_7	395493.BegalDRAFT_0308	2.193e-58	206.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,4602W@72273|Thiotrichales	72273|Thiotrichales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_3327808_6	1123367.C666_14400	1.064e-62	231.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,2KWFV@206389|Rhodocyclales	206389|Rhodocyclales	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS1_k127_3327808_3	1157708.KB907464_gene470	2.147e-97	329.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2VJSB@28216|Betaproteobacteria,4AGR7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
CMS1_k127_3327808_1	794846.AJQU01000039_gene4974	8.87e-231	726.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,4BBS0@82115|Rhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_3327808_10	314260.PB2503_10479	3.135e-38	148.0	COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria,2UFEE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS1_k127_3327808_8	266264.Rmet_5184	4.946e-52	190.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VQS2@28216|Betaproteobacteria,1K73R@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_3327808_4	258594.RPA3210	2.069e-83	294.0	COG0412@1|root,COG0412@2|Bacteria,1R3DI@1224|Proteobacteria,2TVEH@28211|Alphaproteobacteria,3JXJM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_3327808_2	1541065.JRFE01000026_gene2161	6.297e-102	343.0	COG0530@1|root,COG0530@2|Bacteria,1G7C1@1117|Cyanobacteria	1117|Cyanobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_3327808_5	1123393.KB891316_gene1648	2.094e-76	260.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,2VQHR@28216|Betaproteobacteria,1KRVM@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
CMS1_k127_3327808_0	472759.Nhal_1635	8.751e-233	741.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria,1WXPA@135613|Chromatiales	135613|Chromatiales	I	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2,SNARE_assoc
CMS1_k127_3327808_9	323848.Nmul_A1524	6.294e-51	198.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VQ9I@28216|Betaproteobacteria,371PA@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_3463352_18	335543.Sfum_3243	1.412e-41	164.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42SJA@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_4,PAS_9
CMS1_k127_3463352_24	335543.Sfum_1663	1.063e-15	83.0	COG2197@1|root,COG2197@2|Bacteria,1NDB6@1224|Proteobacteria,4326W@68525|delta/epsilon subdivisions,2X61P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3463352_2	1123518.ARWI01000001_gene1641	3.891e-207	652.0	COG2132@1|root,COG2132@2|Bacteria,1R89G@1224|Proteobacteria,1S5X0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
CMS1_k127_3463352_4	1535422.ND16A_1815	1.824e-181	588.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_3463352_0	1535422.ND16A_1814	0.0	2392.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
CMS1_k127_3463352_14	1535422.ND16A_1813	5.013e-50	184.0	2DQ3J@1|root,334KB@2|Bacteria,1NFUT@1224|Proteobacteria,1SH2X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3463352_10	1123518.ARWI01000001_gene1637	7.359e-73	253.0	COG2834@1|root,COG2834@2|Bacteria,1R8JU@1224|Proteobacteria,1SKB0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3463352_19	1123518.ARWI01000001_gene1636	2.314e-40	162.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,1SZFZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_3463352_8	1123518.ARWI01000001_gene1635	3.655e-100	349.0	COG2010@1|root,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,1T01Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
CMS1_k127_3463352_12	909663.KI867150_gene711	2.519e-63	226.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,43A29@68525|delta/epsilon subdivisions,2X21K@28221|Deltaproteobacteria,2MS4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
CMS1_k127_3463352_11	1485544.JQKP01000001_gene954	1.586e-66	231.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR66@28216|Betaproteobacteria,44WGP@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Type II secretion system (T2SS), protein G	gspG2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_3463352_6	580332.Slit_1831	1.187e-154	497.0	COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,2VJ0W@28216|Betaproteobacteria,44WAF@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_3463352_1	1123368.AUIS01000016_gene2551	2.031e-234	765.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2NCBG@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS1_k127_3463352_16	580332.Slit_1829	7.873e-44	173.0	2BGQG@1|root,32APG@2|Bacteria,1PXFZ@1224|Proteobacteria,2WCW7@28216|Betaproteobacteria,44WJ8@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3463352_21	1095769.CAHF01000022_gene425	7.648e-24	109.0	2E3Q5@1|root,32YN4@2|Bacteria,1NA23@1224|Proteobacteria,2VVXW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilN
CMS1_k127_3463352_20	1144319.PMI16_01875	5.172e-29	124.0	COG3167@1|root,COG3167@2|Bacteria,1NKE0@1224|Proteobacteria,2VXXU@28216|Betaproteobacteria,4787S@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	PilO
CMS1_k127_3463352_23	580332.Slit_1826	1.578e-19	100.0	2E5FR@1|root,3307F@2|Bacteria,1N89J@1224|Proteobacteria,2VVS4@28216|Betaproteobacteria,44WJM@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3463352_3	666681.M301_0466	1.873e-191	625.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,2KKT1@206350|Nitrosomonadales	28216|Betaproteobacteria	U	type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N
CMS1_k127_3463352_13	1123368.AUIS01000016_gene2545	4.121e-58	205.0	COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,1T58B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_3463352_17	292415.Tbd_1441	7.473e-43	162.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_3463352_15	1123368.AUIS01000016_gene2543	1.739e-45	178.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,1SBEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3463352_9	580332.Slit_1821	2.905e-92	312.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRBV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_3463352_22	292415.Tbd_1006	5.33e-23	113.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CMS1_k127_3463352_25	1449049.JONW01000009_gene4336	2.213e-12	79.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2TVYD@28211|Alphaproteobacteria,2KJD9@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
CMS1_k127_3463352_5	640081.Dsui_0758	6.72e-174	567.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KUY0@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_3463352_7	1163617.SCD_n01508	1.516e-154	497.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria	1224|Proteobacteria	L	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_3547520_4	1217720.ALOX01000087_gene3010	1.432e-189	598.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2TR02@28211|Alphaproteobacteria,2JQR5@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_3547520_8	1007105.PT7_0660	1.217e-110	373.0	COG1804@1|root,COG1804@2|Bacteria,1MWSJ@1224|Proteobacteria,2VPVP@28216|Betaproteobacteria,3T55N@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_3547520_0	1123392.AQWL01000002_gene1978	0.0	1299.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_3547520_13	1123392.AQWL01000002_gene1979	3.53e-76	273.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,1KTBJ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_3547520_24	1051632.TPY_2814	1.462e-13	78.0	COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes	1239|Firmicutes	P	PFAM Heavy metal transport detoxification protein	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
CMS1_k127_3547520_21	76114.ebA6372	1.233e-23	110.0	2C5P4@1|root,3310H@2|Bacteria,1N6V1@1224|Proteobacteria,2VVVI@28216|Betaproteobacteria,2KXKC@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3547520_16	1163617.SCD_n00378	1.321e-37	151.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	CRP FNR family	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_3547520_19	640081.Dsui_1634	1.045e-33	135.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,2KW8T@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_3547520_9	1123368.AUIS01000019_gene1201	6.169e-104	347.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,2NCG9@225057|Acidithiobacillales	225057|Acidithiobacillales	O	DnaJ C terminal domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS1_k127_3547520_15	1485544.JQKP01000002_gene1546	4.477e-55	203.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,44VB0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CMS1_k127_3547520_3	85643.Tmz1t_1289	2.539e-201	640.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,2KVK4@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_3547520_12	667632.KB890218_gene226	2.278e-85	301.0	COG4585@1|root,COG4585@2|Bacteria,1R43J@1224|Proteobacteria,2VPEB@28216|Betaproteobacteria,1K250@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02486	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HATPase_c_2,HisKA_3,PAS,PAS_4,PAS_9
CMS1_k127_3547520_14	296591.Bpro_1167	2.844e-65	235.0	COG2197@1|root,COG2197@2|Bacteria,1RENN@1224|Proteobacteria,2VR4J@28216|Betaproteobacteria,4AETN@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3547520_23	196367.JNFG01000016_gene3999	7.109e-15	82.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VVNY@28216|Betaproteobacteria,1K970@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3547520_11	1121035.AUCH01000001_gene2081	1.302e-88	308.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,2KUDT@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	fnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_3547520_6	1163617.SCD_n01386	7.065e-173	554.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CMS1_k127_3547520_27	522306.CAP2UW1_2727	1.661e-06	55.0	COG2010@1|root,COG2010@2|Bacteria,1NF1C@1224|Proteobacteria,2VVP1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3547520_20	1123392.AQWL01000004_gene2657	1.111e-28	125.0	2DN59@1|root,32VKR@2|Bacteria,1N627@1224|Proteobacteria,2WAKA@28216|Betaproteobacteria,1KT8N@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3547520_17	159087.Daro_0718	1.936e-37	150.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,2KX1A@206389|Rhodocyclales	206389|Rhodocyclales	S	FixH family	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
CMS1_k127_3547520_5	1286631.X805_32530	1.005e-186	600.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KIYJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS1_k127_3547520_7	375286.mma_1634	9.644e-113	374.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4726F@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS1_k127_3547520_26	1117647.M5M_08005	6.521e-07	59.0	COG4736@1|root,COG4736@2|Bacteria,1QEFV@1224|Proteobacteria,1TB54@1236|Gammaproteobacteria,1J781@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG4736 Cbb3-type cytochrome oxidase, subunit 3	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
CMS1_k127_3547520_10	1454004.AW11_01637	3.163e-100	329.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,1KQIV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CMS1_k127_3547520_1	1235457.C404_08995	3.376e-276	854.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1K44Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CMS1_k127_3547520_25	279714.FuraDRAFT_0747	1.749e-09	71.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2VWG5@28216|Betaproteobacteria,2KS1K@206351|Neisseriales	206351|Neisseriales	P	cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS1_k127_3547520_2	292415.Tbd_2044	6.843e-218	710.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KRHF@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Putative metal-binding domain of cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_3547520_18	1454004.AW11_00331	5.442e-37	148.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_3547520_22	1218084.BBJK01000002_gene149	3.099e-16	80.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,1K75H@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_35853_11	1169143.KB911037_gene4227	2.136e-154	531.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,2VXDK@28216|Betaproteobacteria,1K5E1@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS1_k127_35853_20	1380394.JADL01000009_gene3398	3.648e-83	282.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,2JYIB@204441|Rhodospirillales	204441|Rhodospirillales	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS1_k127_35853_29	1038869.AXAN01000024_gene1718	1.365e-54	198.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VU5R@28216|Betaproteobacteria,1K7A9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CMS1_k127_35853_15	1163617.SCD_n02456	4.631e-111	374.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Tyrosine recombinase xerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_35853_28	267608.RSc2545	6.844e-61	228.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,1K2NU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ebsC	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS1_k127_35853_43	765912.Thimo_0559	5.8e-16	89.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1WYI8@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS1_k127_35853_25	859657.RPSI07_0920	1.775e-72	249.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,1K08V@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_35853_39	323848.Nmul_A0896	6.916e-30	125.0	2E1FD@1|root,32WU2@2|Bacteria,1N5M2@1224|Proteobacteria,2VU9Q@28216|Betaproteobacteria,37371@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_35853_36	472759.Nhal_3775	1.395e-34	137.0	COG4274@1|root,COG4274@2|Bacteria,1N83R@1224|Proteobacteria,1ST4N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
CMS1_k127_35853_14	1121035.AUCH01000005_gene63	1.969e-137	445.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,2KUA8@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_35853_38	522306.CAP2UW1_0459	4.352e-31	122.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,1KQ3W@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS1_k127_35853_31	1123392.AQWL01000005_gene3126	8.394e-50	182.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,1KT2Y@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Yqey-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YqeY
CMS1_k127_35853_7	1163617.SCD_n02448	1.573e-177	574.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS1_k127_35853_1	1163617.SCD_n02447	1.446e-269	849.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_35853_46	1122211.JMLW01000001_gene2372	2.353e-06	55.0	2FF1X@1|root,34709@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_35853_42	1000565.METUNv1_02958	2.101e-17	96.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria,2KVUH@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_35853_47	292415.Tbd_1444	4.313e-05	48.0	28XFS@1|root,2ZJDB@2|Bacteria,1P87W@1224|Proteobacteria,2W690@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
CMS1_k127_35853_35	472759.Nhal_2115	1.667e-40	157.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_35853_34	502025.Hoch_5501	3.591e-44	164.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,42TUY@68525|delta/epsilon subdivisions,2WQCV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
CMS1_k127_35853_3	1500894.JQNN01000001_gene3076	5.76e-256	811.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,2W0JF@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS1_k127_35853_37	1123368.AUIS01000003_gene1841	6.937e-33	130.0	COG4783@1|root,COG4783@2|Bacteria,1N76P@1224|Proteobacteria,1T4CE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS1_k127_35853_30	159087.Daro_0355	1.238e-50	183.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,2KWF2@206389|Rhodocyclales	206389|Rhodocyclales	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_35853_4	640081.Dsui_0311	1.658e-251	809.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,2KUCJ@206389|Rhodocyclales	206389|Rhodocyclales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS1_k127_35853_17	381666.H16_A3107	3.636e-105	351.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,1K3QR@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_35853_2	1121035.AUCH01000022_gene3198	8.377e-258	800.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,2KVEB@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CMS1_k127_35853_33	1288494.EBAPG3_26710	7.307e-45	164.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,373D1@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS1_k127_35853_0	640081.Dsui_0283	1.591e-286	887.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,2KUH8@206389|Rhodocyclales	206389|Rhodocyclales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_35853_27	1234364.AMSF01000003_gene2448	2.159e-67	239.0	COG2890@1|root,COG2890@2|Bacteria,1QYJ3@1224|Proteobacteria,1T5E3@1236|Gammaproteobacteria,1XDC4@135614|Xanthomonadales	135614|Xanthomonadales	J	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
CMS1_k127_35853_8	522306.CAP2UW1_1014	2.737e-170	549.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KQIU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_35853_41	1159870.KB907784_gene582	2.175e-24	112.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,3T4E3@506|Alcaligenaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA1	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_35853_9	1288494.EBAPG3_27080	2.543e-167	539.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,372JY@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS1_k127_35853_10	402626.Rpic_3146	4.61e-163	522.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1K2D1@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_35853_24	1385515.N791_02130	1.062e-72	269.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales	135614|Xanthomonadales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS1_k127_35853_32	76114.ebA1175	4.788e-48	173.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,2KWQF@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CMS1_k127_35853_18	572477.Alvin_3111	2.142e-97	327.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales	135613|Chromatiales	G	PFAM Fructosamine	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CMS1_k127_35853_12	640081.Dsui_0112	1.622e-153	517.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KU89@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
CMS1_k127_35853_5	228410.NE1854	4.35e-203	644.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,371N1@32003|Nitrosomonadales	28216|Betaproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_35853_19	1165096.ARWF01000001_gene1470	7.831e-85	291.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,2KM4E@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
CMS1_k127_35853_22	76114.ebA1169	1.57e-76	271.0	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,2VPZX@28216|Betaproteobacteria,2KVZZ@206389|Rhodocyclales	206389|Rhodocyclales	K	LytTr DNA-binding domain	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
CMS1_k127_35853_40	1304883.KI912532_gene1324	1.502e-25	114.0	COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,2WGR9@28216|Betaproteobacteria,2KYY9@206389|Rhodocyclales	206389|Rhodocyclales	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_35853_16	62928.azo0993	7.26e-107	355.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,2KVQ9@206389|Rhodocyclales	206389|Rhodocyclales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS1_k127_35853_23	323848.Nmul_A2689	2.522e-74	265.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,371TG@32003|Nitrosomonadales	28216|Betaproteobacteria	H	uroporphyrinogen III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS1_k127_35853_21	640081.Dsui_1600	9.829e-79	277.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria,2KW9U@206389|Rhodocyclales	206389|Rhodocyclales	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107	ko:K02496	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	HemX
CMS1_k127_35853_26	1163617.SCD_n02795	9.271e-71	255.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria	28216|Betaproteobacteria	H	HemY domain protein	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_12
CMS1_k127_35853_13	1304883.KI912532_gene1330	8.107e-147	472.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,2KV9H@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS1_k127_35853_6	1031711.RSPO_c01243	3.52e-196	619.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,1K12P@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS1_k127_3588842_14	1121861.KB899919_gene2714	2.134e-61	219.0	COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2TRIZ@28211|Alphaproteobacteria,2JQ9Z@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3,HMGL-like
CMS1_k127_3588842_8	1123504.JQKD01000008_gene5347	3.603e-119	389.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VHK4@28216|Betaproteobacteria,4AJ7S@80864|Comamonadaceae	28216|Betaproteobacteria	E	Pyruvate carboxyltransferase	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS1_k127_3588842_12	1121033.AUCF01000026_gene2992	1.235e-73	275.0	COG2807@1|root,COG2807@2|Bacteria,1QU85@1224|Proteobacteria,2TXRC@28211|Alphaproteobacteria,2JZ2E@204441|Rhodospirillales	204441|Rhodospirillales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3588842_2	94624.Bpet0784	3.047e-265	824.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,3T1SC@506|Alcaligenaceae	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
CMS1_k127_3588842_1	1163617.SCD_n01957	0.0	1012.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_3588842_22	296591.Bpro_4148	3.003e-15	78.0	2DNR5@1|root,32YQH@2|Bacteria,1NBXJ@1224|Proteobacteria,2VW7K@28216|Betaproteobacteria,4AIUC@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3588842_0	296591.Bpro_4149	0.0	1183.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
CMS1_k127_3588842_18	1318628.MARLIPOL_05410	2.525e-36	160.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,46B2G@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3588842_5	296591.Bpro_4151	1.926e-173	570.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,4AD1W@80864|Comamonadaceae	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS1_k127_3588842_9	497321.C664_06653	2.193e-117	403.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,2KVCU@206389|Rhodocyclales	206389|Rhodocyclales	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS1_k127_3588842_15	640081.Dsui_1581	1.487e-55	216.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VM61@28216|Betaproteobacteria,2KW2G@206389|Rhodocyclales	206389|Rhodocyclales	K	LuxR family transcriptional regulator	-	-	-	ko:K13041	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_3588842_13	396588.Tgr7_1020	1.868e-64	228.0	2E55J@1|root,302RV@2|Bacteria,1RFMA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3588842_21	1469245.JFBG01000027_gene1496	6.084e-29	121.0	COG4327@1|root,COG4327@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4212)	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	DUF4212
CMS1_k127_3588842_3	1469245.JFBG01000027_gene1495	1.524e-263	822.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS1_k127_3588842_20	909943.HIMB100_00017300	9.668e-30	119.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2TTA4@28211|Alphaproteobacteria,4BPV6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yjcG	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	DUF4212,SSF
CMS1_k127_3588842_16	713586.KB900536_gene3075	7.056e-53	188.0	2CXUS@1|root,32T2P@2|Bacteria,1MZIZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
CMS1_k127_3588842_4	640081.Dsui_1809	2.318e-177	570.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KUDK@206389|Rhodocyclales	206389|Rhodocyclales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
CMS1_k127_3588842_17	323848.Nmul_A1857	9.769e-47	171.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,373BM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS1_k127_3588842_11	883126.HMPREF9710_05068	1.093e-81	276.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,4724K@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS1_k127_3588842_10	595537.Varpa_2509	2.892e-116	395.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,4A9W3@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
CMS1_k127_3588842_6	388051.AUFE01000009_gene1746	4.985e-130	432.0	COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2VHGX@28216|Betaproteobacteria,1KGMZ@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS1_k127_3588842_7	1071679.BG57_15300	1.238e-124	404.0	COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,2VI9N@28216|Betaproteobacteria,1K17T@119060|Burkholderiaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_3588842_24	1247024.JRLH01000001_gene1010	1.262e-08	56.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3588842_19	1122244.AUGF01000070_gene953	8.202e-31	121.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,1SDC6@1236|Gammaproteobacteria,3NRXM@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3596079_3	765913.ThidrDRAFT_4248	1.094e-17	83.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,1X05D@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
CMS1_k127_3596079_0	1205680.CAKO01000007_gene4414	1.142e-170	543.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JZCB@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS1_k127_3596079_1	1198452.Jab_2c04420	7.428e-168	546.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VJD4@28216|Betaproteobacteria,475EY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS1_k127_3596079_2	1538295.JY96_08125	5.092e-110	368.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VITU@28216|Betaproteobacteria,1KKRP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_3649558_21	1123393.KB891316_gene2087	2.801e-11	65.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,1KS7I@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_3649558_16	264198.Reut_A0750	4.061e-42	157.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria,1K7NH@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM Rhodanese domain protein	pspE2	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_3649558_13	335283.Neut_0197	4.091e-79	270.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,3720E@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Ribosomal RNA adenine dimethylase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_3649558_1	1266925.JHVX01000012_gene1724	0.0	1083.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,371QW@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS1_k127_3649558_14	1123239.KB898624_gene1960	1.538e-56	207.0	COG1073@1|root,COG1073@2|Bacteria,1V7R5@1239|Firmicutes	1239|Firmicutes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_3649558_8	580332.Slit_2416	2.704e-129	428.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
CMS1_k127_3649558_11	1163617.SCD_n02921	2.349e-109	361.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS1_k127_3649558_15	1288494.EBAPG3_1470	1.122e-51	187.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,374M5@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_3649558_4	1266925.JHVX01000012_gene1727	1.752e-250	781.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,372EA@32003|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS1_k127_3649558_19	62928.azo0737	2.426e-29	125.0	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,2KWKW@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
CMS1_k127_3649558_9	640081.Dsui_1050	1.414e-123	414.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_3649558_6	159087.Daro_3758	3.122e-217	682.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KV3K@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3649558_5	1038869.AXAN01000010_gene5129	1.756e-233	735.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2VJK0@28216|Betaproteobacteria,1K4T4@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
CMS1_k127_3649558_18	519989.ECTPHS_10636	1.399e-30	135.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1WYJV@135613|Chromatiales	135613|Chromatiales	M	pfam nlp p60	-	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	NLPC_P60
CMS1_k127_3649558_22	420662.Mpe_A0549	7.797e-11	67.0	2ETEI@1|root,33KYE@2|Bacteria,1NJKD@1224|Proteobacteria,2W43N@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3649558_17	1411123.JQNH01000001_gene964	1.069e-39	156.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	MA20_22025	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS1_k127_3649558_10	1123392.AQWL01000005_gene3180	1.61e-119	394.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,1KRN6@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_3649558_20	1198452.Jab_2c25430	1.868e-26	117.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,4748P@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
CMS1_k127_3649558_2	1485544.JQKP01000012_gene2151	2.675e-310	964.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,44VER@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS1_k127_3649558_12	1123504.JQKD01000031_gene4531	4.744e-109	367.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,4AAPJ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS1_k127_3649558_0	94624.Bpet3019	0.0	1356.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,3T2IP@506|Alcaligenaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS1_k127_3649558_7	1095769.CAHF01000013_gene3196	2.801e-195	645.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,4733P@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	1.8.1.4,2.3.1.12	ko:K00382,ko:K00627	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R02569,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_3649558_3	1097668.BYI23_A009060	6.744e-265	827.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,1K1V8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS1_k127_3669694_0	1121861.KB899935_gene468	5.358e-160	510.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,2JQ3B@204441|Rhodospirillales	204441|Rhodospirillales	ET	general L-amino acid-binding periplasmic protein AapJ	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
CMS1_k127_3669694_2	1125863.JAFN01000001_gene1981	4.637e-142	460.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,42NSB@68525|delta/epsilon subdivisions,2WIKP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
CMS1_k127_3669694_1	1336208.JADY01000007_gene1677	2.442e-143	481.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,2JPI5@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0765 ABC-type amino acid transport system, permease component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
CMS1_k127_3669694_4	1121861.KB899912_gene975	3.098e-110	379.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,2JPJB@204441|Rhodospirillales	204441|Rhodospirillales	E	acid transport	-	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
CMS1_k127_3669694_7	1293047.CBMA010000030_gene2135	1.768e-48	190.0	COG0477@1|root,arCOG00147@2157|Archaea,2XVYA@28890|Euryarchaeota,23V29@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3669694_3	323848.Nmul_A0171	2.682e-121	402.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2WGST@28216|Betaproteobacteria,372BA@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	rubB	-	1.18.1.1	ko:K05297,ko:K12265	ko00071,ko05132,map00071,map05132	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_3669694_5	640081.Dsui_0822	2.343e-72	247.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,2KW76@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS1_k127_3669694_8	312153.Pnuc_1377	4.219e-27	115.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,1KACH@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Rubredoxin	rubA1	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
CMS1_k127_3669694_6	1120977.JHUX01000003_gene1728	8.885e-72	248.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria,3NRMI@468|Moraxellaceae	1236|Gammaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_3669694_9	543913.D521_1159	2.13e-20	92.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,1KQCZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3679416_5	765912.Thimo_0241	5.18e-192	605.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales	135613|Chromatiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_3679416_22	1454004.AW11_01420	8.214e-59	209.0	2BZNP@1|root,30717@2|Bacteria,1REWN@1224|Proteobacteria,2VRZH@28216|Betaproteobacteria,1KQZI@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
CMS1_k127_3679416_2	644966.Tmar_1638	5.886e-213	673.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS1_k127_3679416_15	472759.Nhal_2059	4.514e-102	364.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales	135613|Chromatiales	HJ	TIGRFAM alpha-L-glutamate ligase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
CMS1_k127_3679416_12	1415779.JOMH01000001_gene2496	2.454e-118	401.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X4W3@135614|Xanthomonadales	135614|Xanthomonadales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
CMS1_k127_3679416_31	1255043.TVNIR_0562	2.074e-29	133.0	COG4067@1|root,COG4067@2|Bacteria	2|Bacteria	O	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS1_k127_3679416_19	1123060.JONP01000006_gene4698	7.974e-84	298.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria,2JS0R@204441|Rhodospirillales	204441|Rhodospirillales	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS1_k127_3679416_17	1121861.KB899950_gene2352	7.623e-99	342.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria,2JU2U@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS1_k127_3679416_3	887898.HMPREF0551_1671	4.439e-205	650.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,1JZYM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_3679416_1	1163617.SCD_n01950	2.671e-288	932.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
CMS1_k127_3679416_0	522306.CAP2UW1_4068	1.321e-295	932.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,1KQ6A@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS1_k127_3679416_8	1123487.KB892835_gene3518	2.27e-154	492.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,2KUZJ@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_3679416_33	640081.Dsui_3340	9.207e-22	98.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,2KX79@206389|Rhodocyclales	206389|Rhodocyclales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
CMS1_k127_3679416_16	522306.CAP2UW1_2940	1.065e-99	336.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,1KQET@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_3679416_27	640081.Dsui_3342	1.179e-35	153.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2VU96@28216|Betaproteobacteria,2KWYZ@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
CMS1_k127_3679416_13	1304883.KI912532_gene3248	3.79e-115	379.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,2KVC0@206389|Rhodocyclales	206389|Rhodocyclales	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
CMS1_k127_3679416_4	1304883.KI912532_gene3249	1.003e-202	662.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,2KUJY@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphoglucomutase	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_3679416_18	76114.p2A113	3.395e-85	305.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,2KVP4@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CMS1_k127_3679416_35	159087.Daro_3304	1.333e-19	93.0	2EIBB@1|root,33C2R@2|Bacteria,1NETH@1224|Proteobacteria,2VXET@28216|Betaproteobacteria,2KXHM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3679416_20	1198452.Jab_1c16820	9.144e-71	254.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2VKF6@28216|Betaproteobacteria,47371@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_3679416_23	1123519.PSJM300_18110	2.589e-47	180.0	COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,1S5W6@1236|Gammaproteobacteria,1Z02X@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	COG0466 ATP-dependent Lon protease, bacterial type	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
CMS1_k127_3679416_9	1366050.N234_13495	1.262e-138	460.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,1K28G@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	ugpC	-	3.6.3.20	ko:K05816,ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
CMS1_k127_3679416_11	1003200.AXXA_24235	2.809e-126	410.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2VICF@28216|Betaproteobacteria,3T1RD@506|Alcaligenaceae	28216|Betaproteobacteria	G	probably responsible for the translocation of the substrate across the membrane	ugpE	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_3679416_10	859657.RPSI07_2100	2.005e-129	419.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2VH0I@28216|Betaproteobacteria,1K1RU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_3679416_6	331869.BAL199_10135	1.403e-170	545.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2TQKV@28211|Alphaproteobacteria,4BPN6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
CMS1_k127_3679416_14	1144342.PMI40_04278	1.828e-108	366.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2VH0F@28216|Betaproteobacteria,4765N@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	transport system, periplasmic component	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
CMS1_k127_3679416_7	331869.BAL199_25059	3.369e-159	517.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria,4BRRD@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	MA20_32350	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS1_k127_3679416_26	1122603.ATVI01000010_gene938	5.982e-36	152.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1X4H7@135614|Xanthomonadales	135614|Xanthomonadales	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS1_k127_3679416_21	76114.ebA4111	1.402e-63	228.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,2KW3H@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS1_k127_3679416_28	1198452.Jab_1c11290	7.011e-34	149.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria,474Z2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_3679416_34	251229.Chro_1883	1.072e-20	96.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PG_binding_1,Response_reg,dCache_1
CMS1_k127_3679416_38	411467.BACCAP_00246	1.992e-05	49.0	2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3679416_29	1123367.C666_05425	1.825e-30	135.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Tfp pilus assembly protein	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
CMS1_k127_3679416_25	1454004.AW11_01626	3.531e-38	158.0	COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VWAB@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
CMS1_k127_3679416_32	1163617.SCD_n02124	2.368e-24	107.0	COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
CMS1_k127_3679416_24	375286.mma_3357	7.117e-41	173.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	ppdB	-	-	ko:K02459,ko:K02672,ko:K02680	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_3679416_37	583345.Mmol_2270	6.591e-06	58.0	COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria,2KNA2@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3686086_1	519989.ECTPHS_06582	2.413e-89	307.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WXM6@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_3686086_6	243365.CV_2041	9.593e-12	68.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2VWG5@28216|Betaproteobacteria,2KS1K@206351|Neisseriales	206351|Neisseriales	P	cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS1_k127_3686086_2	926560.KE387025_gene3982	3.161e-81	279.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3686086_7	1249627.D779_0293	1.255e-09	70.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,1RQE8@1236|Gammaproteobacteria,1X20C@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_3686086_5	926560.KE387025_gene3980	5.422e-28	128.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_3686086_0	1049564.TevJSym_al00220	2.309e-118	392.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1J7IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3686086_3	1177154.Y5S_00276	3.454e-77	267.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XHXM@135619|Oceanospirillales	135619|Oceanospirillales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS1_k127_3686086_4	266117.Rxyl_0056	1.15e-28	118.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
CMS1_k127_3722686_14	1124983.PFLCHA0_c15070	1.873e-43	171.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1YTKF@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	U	Extended Signal Peptide of Type V secretion system	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
CMS1_k127_3722686_8	1430440.MGMSRv2_1977	5.116e-84	303.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,2U04Z@28211|Alphaproteobacteria,2JT2T@204441|Rhodospirillales	204441|Rhodospirillales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
CMS1_k127_3722686_6	234621.RER_56000	2.395e-123	401.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4FVWI@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA4	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_3722686_9	1385517.N800_06100	3.071e-75	258.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,1S4K8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	5.99.1.4	ko:K14584	ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220	M00534	R05137	RC03084	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DSBA
CMS1_k127_3722686_12	876269.ARWA01000001_gene1218	3.879e-54	204.0	COG0412@1|root,COG0412@2|Bacteria,1R5J6@1224|Proteobacteria,2UE6V@28211|Alphaproteobacteria,3NBMH@45404|Beijerinckiaceae	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
CMS1_k127_3722686_5	522772.Dacet_0784	1.278e-156	524.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS1_k127_3722686_0	1265502.KB905934_gene3292	0.0	1626.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,4AC69@80864|Comamonadaceae	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS1_k127_3722686_15	497321.C664_10727	2.015e-32	132.0	COG1846@1|root,COG1846@2|Bacteria,1PW9W@1224|Proteobacteria,2VUDE@28216|Betaproteobacteria,2KW70@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_3722686_10	292415.Tbd_2162	8.031e-55	202.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
CMS1_k127_3722686_7	153948.NAL212_0218	3.754e-121	404.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,372KF@32003|Nitrosomonadales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_3722686_3	1304883.KI912532_gene2831	7.057e-172	553.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KVT7@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
CMS1_k127_3722686_1	1132855.KB913035_gene1495	0.0	1606.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KMG8@206350|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS1_k127_3722686_11	1000565.METUNv1_02334	3.368e-54	199.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria,2KWQ6@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	5-FTHF_cyc-lig
CMS1_k127_3722686_13	748247.AZKH_3911	8.326e-45	174.0	COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria,2VUPT@28216|Betaproteobacteria,2KZBS@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_3722686_4	1207063.P24_01956	4.868e-164	528.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,2JQXD@204441|Rhodospirillales	204441|Rhodospirillales	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_3722686_2	1163617.SCD_n02239	1.922e-290	908.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
CMS1_k127_3762611_1	1123393.KB891329_gene1010	6.584e-81	279.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2VKZJ@28216|Betaproteobacteria,1KT64@119069|Hydrogenophilales	119069|Hydrogenophilales	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS1_k127_3762611_2	1280954.HPO_06473	2.774e-08	63.0	COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria,2UTTI@28211|Alphaproteobacteria,43XIG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS1_k127_3762611_0	396588.Tgr7_1594	1.166e-87	291.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_3773181_16	380394.Lferr_1738	1.886e-07	55.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,1T1IP@1236|Gammaproteobacteria,2NCIU@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
CMS1_k127_3773181_4	228410.NE2030	9.081e-181	575.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,372V3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_3773181_5	1288494.EBAPG3_21160	5.242e-157	511.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,37202@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS1_k127_3773181_0	323848.Nmul_A0715	0.0	1097.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria,372UR@32003|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS1_k127_3773181_14	1121920.AUAU01000017_gene1225	7.527e-28	118.0	COG0748@1|root,COG0748@2|Bacteria,3Y2Q3@57723|Acidobacteria	57723|Acidobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Pyrid_oxidase_2
CMS1_k127_3773181_12	1071679.BG57_15920	3.776e-45	178.0	2BXI0@1|root,2Z9A2@2|Bacteria,1MZF7@1224|Proteobacteria,2VSVG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
CMS1_k127_3773181_11	1298867.AUES01000029_gene2410	1.889e-79	278.0	COG0583@1|root,COG0583@2|Bacteria,1R7ER@1224|Proteobacteria,2U0PW@28211|Alphaproteobacteria,3JW8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3773181_10	1231190.NA8A_14554	1.086e-99	342.0	COG2358@1|root,COG2358@2|Bacteria,1N5B1@1224|Proteobacteria,2UENJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
CMS1_k127_3773181_3	1231190.NA8A_14559	2.096e-184	596.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,43H4B@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3773181_2	1298867.AUES01000029_gene2409	1.411e-188	596.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3JTSN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_3773181_6	159450.NH14_16320	6.929e-147	479.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJJQ@28216|Betaproteobacteria,1K237@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS1_k127_3773181_13	1454004.AW11_01675	2.072e-30	124.0	COG1977@1|root,COG1977@2|Bacteria,1N9QE@1224|Proteobacteria,2VVR6@28216|Betaproteobacteria	28216|Betaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_3773181_1	1380394.JADL01000014_gene240	7.99e-200	628.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,2JRNW@204441|Rhodospirillales	204441|Rhodospirillales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3773181_7	1205680.CAKO01000010_gene3927	7.511e-121	405.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria,2JR9Q@204441|Rhodospirillales	204441|Rhodospirillales	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS1_k127_3773181_8	1205680.CAKO01000010_gene3929	6.394e-110	363.0	COG3618@1|root,COG3618@2|Bacteria,1QWWJ@1224|Proteobacteria,2TV8V@28211|Alphaproteobacteria,2JVWZ@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3773181_9	1123242.JH636434_gene3342	6.531e-103	342.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS1_k127_3778230_5	1382306.JNIM01000001_gene1023	1.253e-236	760.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_3778230_16	1382306.JNIM01000001_gene1022	3.101e-58	211.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_3778230_9	314278.NB231_13521	8.589e-151	489.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_3778230_13	296591.Bpro_3022	9.087e-110	364.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria,4A9VB@80864|Comamonadaceae	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3778230_0	338963.Pcar_2557	2.198e-283	889.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,43UHA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bifunctional transglycosylase second domain	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
CMS1_k127_3778230_19	1232410.KI421426_gene1441	1.255e-32	131.0	COG3063@1|root,COG3063@2|Bacteria,1QZ5S@1224|Proteobacteria,42XK8@68525|delta/epsilon subdivisions,2WSKB@28221|Deltaproteobacteria,43V3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3778230_7	1454004.AW11_03577	1.005e-174	565.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2VJXC@28216|Betaproteobacteria,1KQNM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3778230_22	713586.KB900536_gene1526	0.0003006	46.0	2C8F7@1|root,33A2N@2|Bacteria,1NH9E@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Hypoxia induced protein conserved region	MA20_20545	-	-	-	-	-	-	-	-	-	-	-	HIG_1_N
CMS1_k127_3778230_11	1144310.PMI07_005444	1.807e-141	456.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,4BCRD@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS1_k127_3778230_20	1121935.AQXX01000005_gene681	4.859e-31	126.0	2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3778230_4	62928.azo3052	3.384e-242	758.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,2KY7V@206389|Rhodocyclales	206389|Rhodocyclales	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3778230_17	1380394.JADL01000003_gene5180	1.277e-47	176.0	COG0369@1|root,COG0369@2|Bacteria,1QUX0@1224|Proteobacteria,2U85Q@28211|Alphaproteobacteria,2JXR2@204441|Rhodospirillales	204441|Rhodospirillales	P	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
CMS1_k127_3778230_15	748247.AZKH_2136	7.274e-83	285.0	COG0703@1|root,COG1476@1|root,COG0703@2|Bacteria,COG1476@2|Bacteria,1MX66@1224|Proteobacteria,2VK91@28216|Betaproteobacteria,2KYFD@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	bzdR	-	-	ko:K15546	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,SKI
CMS1_k127_3778230_1	388051.AUFE01000023_gene4556	3.751e-262	818.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,2VKSK@28216|Betaproteobacteria	28216|Betaproteobacteria	I	enoyl-CoA hydratase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS1_k127_3778230_2	62928.azo3057	4.577e-259	829.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,2KVI4@206389|Rhodocyclales	206389|Rhodocyclales	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_3778230_8	748247.AZKH_4520	1.375e-161	526.0	COG0369@1|root,COG1149@1|root,COG0369@2|Bacteria,COG1149@2|Bacteria,1NCKQ@1224|Proteobacteria,2VIZE@28216|Betaproteobacteria,2KY3Q@206389|Rhodocyclales	206389|Rhodocyclales	C	Oxidoreductase NAD-binding domain	boxA	-	1.14.13.208	ko:K15511	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer4,NAD_binding_1
CMS1_k127_3778230_3	1380394.JADL01000003_gene5164	4.168e-246	766.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_3778230_14	671143.DAMO_1717	5.257e-87	306.0	COG0840@1|root,COG0840@2|Bacteria,2NQS9@2323|unclassified Bacteria	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH,dCache_1
CMS1_k127_3778230_18	296591.Bpro_1647	4.713e-41	162.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,2WG0X@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_3778230_12	1449357.JQLK01000005_gene2419	1.681e-111	387.0	COG1062@1|root,COG1062@2|Bacteria,1WKA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3778230_6	1244869.H261_04842	1.33e-231	730.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,2JPYI@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme	-	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
CMS1_k127_3778230_10	94624.Bpet1218	1.988e-149	484.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria	28216|Betaproteobacteria	G	C4-dicarboxylate transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3778230_21	1461694.ATO9_03870	6.793e-26	114.0	COG3090@1|root,COG3090@2|Bacteria,1RGJ1@1224|Proteobacteria,2U7NZ@28211|Alphaproteobacteria,2PETB@252301|Oceanicola	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_3799257_14	287.DR97_1887	3.455e-132	436.0	COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,1RNGH@1236|Gammaproteobacteria,1YFSM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_3799257_26	1205680.CAKO01000014_gene99	4.619e-75	259.0	COG1028@1|root,COG1028@2|Bacteria,1NCD3@1224|Proteobacteria,2TTFD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3799257_4	1123355.JHYO01000019_gene1694	5.101e-247	774.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2UPRJ@28211|Alphaproteobacteria,36Z8A@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AFOR_C,AFOR_N
CMS1_k127_3799257_1	1266925.JHVX01000003_gene404	0.0	1099.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VHNB@28216|Betaproteobacteria,371VU@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS1_k127_3799257_40	666684.AfiDRAFT_0740	2.138e-35	158.0	COG1225@1|root,COG1225@2|Bacteria,1RA5K@1224|Proteobacteria,2U6EF@28211|Alphaproteobacteria,3K007@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_3799257_3	1288494.EBAPG3_21050	1.957e-265	844.0	COG1330@1|root,COG2887@1|root,COG1330@2|Bacteria,COG2887@2|Bacteria,1QU90@1224|Proteobacteria,2VHNR@28216|Betaproteobacteria,37212@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	PDDEXK_1
CMS1_k127_3799257_39	882378.RBRH_01527	3.331e-36	145.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,1K2YN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS1_k127_3799257_21	522306.CAP2UW1_2480	5.604e-89	310.0	2B3X8@1|root,31WM6@2|Bacteria,1RFRT@1224|Proteobacteria,2VRRY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
CMS1_k127_3799257_29	1232410.KI421418_gene2350	2.42e-67	242.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,42UMQ@68525|delta/epsilon subdivisions,2WQY1@28221|Deltaproteobacteria,43TT0@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
CMS1_k127_3799257_27	1121918.ARWE01000001_gene98	9.351e-72	254.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,42PPJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_3799257_23	1469607.KK073769_gene4981	2.681e-82	281.0	COG0625@1|root,COG0625@2|Bacteria	2|Bacteria	O	glutathione transferase activity	ligE	-	2.5.1.18	ko:K00799,ko:K03675	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000,ko03110	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CMS1_k127_3799257_18	257310.BB2888	1.154e-116	378.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,3T2BC@506|Alcaligenaceae	28216|Betaproteobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
CMS1_k127_3799257_33	637389.Acaty_c0899	1.043e-53	194.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,2NCZF@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS1_k127_3799257_34	1288494.EBAPG3_23470	3.692e-53	191.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,3735G@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_3799257_5	62928.azo1029	1.478e-241	752.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,2KVBW@206389|Rhodocyclales	206389|Rhodocyclales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_3799257_42	582744.Msip34_2322	1.968e-27	113.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,2VU3I@28216|Betaproteobacteria,2KN4F@206350|Nitrosomonadales	206350|Nitrosomonadales	J	PFAM ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS1_k127_3799257_20	640081.Dsui_3220	3.149e-95	334.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,2KUEG@206389|Rhodocyclales	206389|Rhodocyclales	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3799257_13	1304275.C41B8_08825	3.149e-138	459.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS1_k127_3799257_46	1366050.N234_24345	4.348e-17	85.0	2E7PS@1|root,3325B@2|Bacteria,1PVAH@1224|Proteobacteria,2VVUK@28216|Betaproteobacteria,1KAP4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3799257_7	1121033.AUCF01000021_gene2889	4.534e-194	615.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,2JQ2N@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_3799257_31	309801.trd_A0663	1.739e-61	217.0	COG0251@1|root,COG0251@2|Bacteria,2G7G4@200795|Chloroflexi,27Y7P@189775|Thermomicrobia	189775|Thermomicrobia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS1_k127_3799257_25	153948.NAL212_3014	5.051e-80	271.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,372IZ@32003|Nitrosomonadales	28216|Betaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CMS1_k127_3799257_9	261292.Nit79A3_0353	3.262e-153	494.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,372MW@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase M48	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_3799257_35	335283.Neut_2288	6.16e-41	160.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,2WFUX@28216|Betaproteobacteria	28216|Betaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS1_k127_3799257_24	1485544.JQKP01000018_gene575	2.671e-80	280.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,44UZ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS1_k127_3799257_44	1218076.BAYB01000015_gene3245	1.968e-21	102.0	2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,2VX2T@28216|Betaproteobacteria,1K8JC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS1_k127_3799257_22	640081.Dsui_3240	2.229e-85	296.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,2KUFS@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CMS1_k127_3799257_30	748247.AZKH_3223	1.463e-62	222.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,2KWCT@206389|Rhodocyclales	206389|Rhodocyclales	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_3799257_45	748247.AZKH_4235	1.568e-18	98.0	2END2@1|root,33G0J@2|Bacteria,1NIFI@1224|Proteobacteria,2VVU7@28216|Betaproteobacteria,2KZCF@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3799257_12	1210884.HG799463_gene9456	9.337e-146	467.0	COG0604@1|root,COG0604@2|Bacteria,2J3EE@203682|Planctomycetes	203682|Planctomycetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3799257_43	85643.Tmz1t_3357	1.356e-23	106.0	2EDY7@1|root,337T3@2|Bacteria,1RKSZ@1224|Proteobacteria,2VTSJ@28216|Betaproteobacteria,2KWV4@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3799257_15	1000565.METUNv1_00266	3.819e-129	429.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,2KUYE@206389|Rhodocyclales	206389|Rhodocyclales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_3799257_2	640081.Dsui_0130	0.0	1058.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_3799257_17	748247.AZKH_0631	4.353e-128	421.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,2KU9I@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_3799257_38	748247.AZKH_0630	1.658e-36	147.0	COG0741@1|root,COG0741@2|Bacteria,1RAP3@1224|Proteobacteria,2VQXG@28216|Betaproteobacteria,2KWVV@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_3799257_49	257310.BB4378	4.291e-07	56.0	2ANGV@1|root,31DFK@2|Bacteria,1RJ5C@1224|Proteobacteria,2VSDR@28216|Betaproteobacteria,3T41B@506|Alcaligenaceae	28216|Betaproteobacteria	S	Histone H1-like nucleoprotein HC2	hctB	-	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	HC2
CMS1_k127_3799257_48	357808.RoseRS_1993	1.615e-10	65.0	2DQJV@1|root,337C3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
CMS1_k127_3799257_6	1288494.EBAPG3_27830	7.246e-209	655.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,371XR@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS1_k127_3799257_0	323848.Nmul_A2468	0.0	1459.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,372QB@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_3799257_32	1266925.JHVX01000009_gene44	4.653e-61	228.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,3731N@32003|Nitrosomonadales	28216|Betaproteobacteria	V	N-acetylmuramoyl-L-alanine amidase (Family 2)	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
CMS1_k127_3799257_10	1123392.AQWL01000001_gene1606	2.02e-152	505.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KSDB@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3799257_19	522306.CAP2UW1_0767	9.072e-111	380.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,2WGR4@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
CMS1_k127_3799257_47	1288494.EBAPG3_16220	3.79e-12	72.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,373QW@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_3799257_16	640081.Dsui_0162	1.774e-128	420.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,2KV65@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_3799257_36	522306.CAP2UW1_0764	9.867e-40	149.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,1KQ1U@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS1_k127_3799257_41	626418.bglu_1g04840	2.939e-34	132.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,1K8IM@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS1_k127_3799257_11	1163617.SCD_n02108	6.835e-152	488.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS1_k127_3799257_8	323848.Nmul_A1843	1.058e-164	526.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,3722B@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS1_k127_3799257_28	1288494.EBAPG3_16120	1.743e-71	248.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,2VQUX@28216|Betaproteobacteria,372TE@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
CMS1_k127_3799257_37	1158292.JPOE01000005_gene357	9.183e-38	141.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,1KKQS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_3813235_37	305700.B447_11492	7.408e-46	168.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,2KW8P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_3813235_7	1454004.AW11_02734	7.737e-174	561.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,1KQH6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	MoeA N-terminal region (domain I and II)	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_3813235_44	1223521.BBJX01000005_gene1937	9.225e-23	105.0	COG2050@1|root,COG2050@2|Bacteria,1RHP8@1224|Proteobacteria,2VY16@28216|Betaproteobacteria,4AFY8@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_3813235_36	580332.Slit_2524	3.273e-55	219.0	COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2VRQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
CMS1_k127_3813235_2	580332.Slit_2523	8.267e-309	966.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2VIAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
CMS1_k127_3813235_17	1266925.JHVX01000001_gene2483	2.202e-122	403.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2WAY9@28216|Betaproteobacteria,371NX@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS1_k127_3813235_41	748247.AZKH_0481	2.605e-29	126.0	COG3154@1|root,COG3154@2|Bacteria,1RB7T@1224|Proteobacteria,2VTWW@28216|Betaproteobacteria,2KXAD@206389|Rhodocyclales	206389|Rhodocyclales	I	lipid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_3813235_20	1163617.SCD_n00430	4.632e-112	387.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
CMS1_k127_3813235_9	748247.AZKH_0483	3.41e-160	517.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KU9W@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CMS1_k127_3813235_47	1333856.L686_20210	1.944e-12	77.0	2C19D@1|root,2Z7PA@2|Bacteria,1MY1F@1224|Proteobacteria,1RQ3A@1236|Gammaproteobacteria,1Z2E2@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Maltose operon periplasmic protein precursor (MalM)	malM	-	-	ko:K05775	-	-	-	-	ko00000	-	-	-	MalM
CMS1_k127_3813235_21	1071679.BG57_24315	5.549e-111	366.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,1K4AM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS1_k127_3813235_32	1485544.JQKP01000001_gene1304	2.714e-76	264.0	COG2230@1|root,COG2230@2|Bacteria,1QXKQ@1224|Proteobacteria,2WHPJ@28216|Betaproteobacteria,44VP5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_3813235_12	572477.Alvin_2598	9.309e-156	508.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales	135613|Chromatiales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS1_k127_3813235_14	582744.Msip34_1733	1.959e-137	448.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,2KM0V@206350|Nitrosomonadales	206350|Nitrosomonadales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS1_k127_3813235_38	1454004.AW11_00600	9.739e-46	169.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,1KQWH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS1_k127_3813235_4	1454004.AW11_00972	3.741e-245	792.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,1KQ8R@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_3813235_26	305700.B447_12669	7.2e-89	299.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,2KUMK@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3813235_35	381666.H16_A1500	9.35e-64	231.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2VRIQ@28216|Betaproteobacteria,1K41R@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS1_k127_3813235_11	640081.Dsui_2309	7.875e-156	501.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,2KUV8@206389|Rhodocyclales	206389|Rhodocyclales	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS1_k127_3813235_18	375286.mma_1536	1.942e-118	393.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,472FU@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
CMS1_k127_3813235_10	292415.Tbd_1006	7.268e-156	520.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CMS1_k127_3813235_15	580332.Slit_1540	9.13e-129	418.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,44W72@713636|Nitrosomonadales	28216|Betaproteobacteria	BQ	PFAM histone deacetylase superfamily	hda	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_3813235_16	580332.Slit_2221	2.19e-126	411.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities AAA_3	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_3813235_31	1034347.CAHJ01000011_gene2311	1.236e-77	274.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,4HBXC@91061|Bacilli,1ZC2D@1386|Bacillus	91061|Bacilli	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	porG	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,POR
CMS1_k127_3813235_0	292459.STH3262	1.123e-315	984.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
CMS1_k127_3813235_29	401526.TcarDRAFT_2301	9.905e-82	281.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,4H2FP@909932|Negativicutes	909932|Negativicutes	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CMS1_k127_3813235_8	340099.Teth39_0216	3.939e-169	551.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS1_k127_3813235_13	1049564.TevJSym_af00670	9.351e-153	496.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1J50C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Na+ dependent nucleoside transporter N-terminus	nupX	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CMS1_k127_3813235_30	631362.Thi970DRAFT_04180	1.396e-78	286.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1WW0C@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS1_k127_3813235_28	1163617.SCD_n00827	6.339e-82	287.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS1_k127_3813235_27	292415.Tbd_1979	2.699e-85	288.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VJMC@28216|Betaproteobacteria,1KSQW@119069|Hydrogenophilales	119069|Hydrogenophilales	S	NADPH-dependent FMN reductase	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS1_k127_3813235_40	1123392.AQWL01000001_gene1482	2.614e-30	137.0	COG3308@1|root,COG3308@2|Bacteria,1N1EF@1224|Proteobacteria,2VU3C@28216|Betaproteobacteria,1KRW6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
CMS1_k127_3813235_45	279714.FuraDRAFT_0533	8.449e-21	103.0	COG3637@1|root,COG3637@2|Bacteria,1N7U7@1224|Proteobacteria,2VRRF@28216|Betaproteobacteria,2KTSV@206351|Neisseriales	206351|Neisseriales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OmpA_membrane
CMS1_k127_3813235_3	1265502.KB905935_gene3128	2.444e-245	767.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,4AAW6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_3813235_39	1384054.N790_03730	6.252e-38	162.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,1X64J@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS1_k127_3813235_24	1366050.N234_32775	1.461e-90	322.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,1K5JW@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM NnrS family protein	nnrS	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
CMS1_k127_3813235_22	1071679.BG57_00525	3.564e-109	358.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1JZXY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_3813235_25	1163617.SCD_n00821	2.39e-90	301.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS1_k127_3813235_5	1265502.KB905935_gene3131	2.811e-180	568.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,4AB67@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_3813235_34	640081.Dsui_3528	4.871e-71	257.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,2KV5Y@206389|Rhodocyclales	206389|Rhodocyclales	E	Acetolactate synthase small	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
CMS1_k127_3813235_1	1266925.JHVX01000003_gene647	7.702e-310	958.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,372AD@32003|Nitrosomonadales	28216|Betaproteobacteria	H	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_3813235_33	640081.Dsui_3530	1.509e-75	258.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,2KW6F@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3813235_46	1163617.SCD_n00816	4.189e-17	87.0	2E95F@1|root,333E6@2|Bacteria,1N8N7@1224|Proteobacteria,2VWBC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3619)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3619
CMS1_k127_3813235_43	1288494.EBAPG3_13520	3.225e-25	117.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,373GC@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
CMS1_k127_3813235_42	864073.HFRIS_018531	5.74e-28	126.0	COG1714@1|root,COG1714@2|Bacteria,1REEC@1224|Proteobacteria,2VRE0@28216|Betaproteobacteria,474MF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_3813235_19	1163617.SCD_n00813	2.838e-117	388.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_3813235_23	76114.ebA7173	3.558e-103	367.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,2KVN9@206389|Rhodocyclales	206389|Rhodocyclales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_3813235_6	1288494.EBAPG3_20840	1.434e-174	559.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,372AV@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS1_k127_3827247_32	1121033.AUCF01000001_gene1954	5.784e-79	270.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2TRRW@28211|Alphaproteobacteria,2JPPZ@204441|Rhodospirillales	204441|Rhodospirillales	S	metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
CMS1_k127_3827247_42	1122929.KB908216_gene1906	1.683e-50	199.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	carbon monoxide dehydrogenase	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS1_k127_3827247_20	402881.Plav_2958	4.832e-133	441.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,1MUHH@1224|Proteobacteria,2TSXR@28211|Alphaproteobacteria,1JNG5@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	VWA domain containing CoxE-like protein	MA20_09405	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_3827247_18	1207063.P24_09931	7.091e-136	439.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria,2JQDG@204441|Rhodospirillales	204441|Rhodospirillales	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS1_k127_3827247_28	331869.BAL199_24784	8.901e-98	328.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TRA8@28211|Alphaproteobacteria,4BPA8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	coxM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_3827247_1	1095769.CAHF01000021_gene882	0.0	1244.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,4747B@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_3827247_37	1121861.KB899917_gene3624	3.454e-69	239.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,2JVN9@204441|Rhodospirillales	204441|Rhodospirillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_3827247_34	1163617.SCD_n02306	1.018e-76	264.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VQRM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3827247_27	1163617.SCD_n02307	4.929e-101	351.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
CMS1_k127_3827247_22	159450.NH14_05590	2.274e-130	426.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,1K1XI@119060|Burkholderiaceae	28216|Betaproteobacteria	O	XdhC and CoxI family	coxI	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS1_k127_3827247_44	279714.FuraDRAFT_1513	1.312e-44	178.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VSIN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Molybdopterin-guanine dinucleotide biosynthesis protein MobA	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_3827247_9	580332.Slit_0650	1.307e-199	628.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,44V8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS1_k127_3827247_39	1123367.C666_18480	5.698e-60	211.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,2KWBU@206389|Rhodocyclales	206389|Rhodocyclales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS1_k127_3827247_16	159087.Daro_0605	1.45e-146	480.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,2KUY4@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS1_k127_3827247_35	977880.RALTA_A2337	2.49e-75	271.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,1K06S@119060|Burkholderiaceae	28216|Betaproteobacteria	H	riboflavin synthase alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS1_k127_3827247_56	935863.AWZR01000001_gene1788	1.785e-11	71.0	2ECBH@1|root,33NQZ@2|Bacteria,1NN62@1224|Proteobacteria,1SHSN@1236|Gammaproteobacteria,1XC58@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3827247_0	522306.CAP2UW1_0646	0.0	1415.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,1KQK8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
CMS1_k127_3827247_47	1163617.SCD_n02473	6.29e-43	171.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
CMS1_k127_3827247_33	1095769.CAHF01000012_gene3418	2.771e-78	281.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2VHTD@28216|Betaproteobacteria,472Z6@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Probable molybdopterin binding domain	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS1_k127_3827247_43	640081.Dsui_1377	3.267e-48	178.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
CMS1_k127_3827247_48	861299.J421_6114	1.837e-39	151.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	fcbC	-	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
CMS1_k127_3827247_40	1121468.AUBR01000032_gene1164	1.393e-53	203.0	COG1085@1|root,COG1085@2|Bacteria,1V675@1239|Firmicutes,24JTF@186801|Clostridia	186801|Clostridia	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3827247_36	640081.Dsui_2861	2.724e-71	252.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VIII@28216|Betaproteobacteria,2KWBA@206389|Rhodocyclales	206389|Rhodocyclales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_3827247_54	76114.ebA2032	3.284e-19	91.0	2EGIY@1|root,33AB5@2|Bacteria,1NPCU@1224|Proteobacteria,2W5VN@28216|Betaproteobacteria,2KZH6@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3827247_3	76114.ebA2099	0.0	1093.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VZ75@28216|Betaproteobacteria,2KXX2@206389|Rhodocyclales	206389|Rhodocyclales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS1_k127_3827247_25	748247.AZKH_0685	1.75e-103	344.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KV7X@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_3827247_41	1123368.AUIS01000009_gene2457	7.15e-52	186.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S8VM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA3	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_3827247_24	1095769.CAHF01000006_gene1723	5.768e-110	366.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,4734U@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS1_k127_3827247_30	267608.RSc2454	1.637e-81	276.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,1K1MB@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS1_k127_3827247_52	1236959.BAMT01000006_gene387	4.509e-25	114.0	COG3170@1|root,COG3170@2|Bacteria,1N3SZ@1224|Proteobacteria,2VU3V@28216|Betaproteobacteria,2KMWK@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS1_k127_3827247_21	1163617.SCD_n02360	2.842e-131	432.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
CMS1_k127_3827247_26	159087.Daro_0238	9.905e-103	345.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,2KUK4@206389|Rhodocyclales	206389|Rhodocyclales	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_3827247_13	1157708.KB907462_gene897	1.211e-176	560.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,4AB2U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
CMS1_k127_3827247_49	399739.Pmen_0276	2.75e-35	141.0	2DF7Q@1|root,32U4W@2|Bacteria,1N0SY@1224|Proteobacteria,1SAUR@1236|Gammaproteobacteria,1YGHI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3827247_53	640081.Dsui_1534	1.771e-21	94.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,2KXDQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS1_k127_3827247_51	742823.HMPREF9465_01493	3.214e-29	119.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,4PRAN@995019|Sutterellaceae	28216|Betaproteobacteria	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS1_k127_3827247_29	1266925.JHVX01000006_gene2161	7.159e-91	305.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,371UQ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_3827247_17	1304883.KI912532_gene3134	5.513e-146	479.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,2KURK@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_3827247_38	1123487.KB892867_gene995	4.388e-62	229.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,2KWAF@206389|Rhodocyclales	206389|Rhodocyclales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS1_k127_3827247_15	1100721.ALKO01000017_gene1688	1.963e-155	501.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,4AA1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	soxF	-	1.8.2.1,1.8.5.4	ko:K05301,ko:K17218	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528,R10152	RC00168,RC03155	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
CMS1_k127_3827247_55	1100721.ALKO01000017_gene1689	1.118e-16	93.0	COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria,2VVR2@28216|Betaproteobacteria,4AFHD@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	soxE	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_3827247_2	265072.Mfla_0508	0.0	1175.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KKYH@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_3827247_45	85643.Tmz1t_1250	2.413e-43	160.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,2KWPQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS1_k127_3827247_50	640081.Dsui_0007	5.596e-35	135.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,2KWX9@206389|Rhodocyclales	206389|Rhodocyclales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_3827247_7	388051.AUFE01000008_gene1583	3.014e-232	722.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria,1K0EF@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Isocitrate dehydrogenase	icd	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_3827247_46	1532557.JL37_03870	4.727e-43	167.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,3T4GB@506|Alcaligenaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS1_k127_3827247_31	312153.Pnuc_1384	1.3e-79	269.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
CMS1_k127_3827247_14	1232683.ADIMK_0084	5.282e-166	541.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS1_k127_3827247_11	1123368.AUIS01000031_gene1420	7.904e-188	612.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales	225057|Acidithiobacillales	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_3827247_8	1100720.ALKN01000028_gene2565	6.327e-230	720.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,4A9RB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_3827247_19	883126.HMPREF9710_03183	2.366e-134	436.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,4725H@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
CMS1_k127_3827247_12	748247.AZKH_1114	1.341e-179	570.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,2KUHR@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
CMS1_k127_3827247_4	1198452.Jab_2c33740	2.672e-279	875.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,473Z4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_3827247_23	314345.SPV1_12290	6.632e-111	368.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria	1224|Proteobacteria	BQ	Including yeast histone deacetylase and acetoin utilization protein	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
CMS1_k127_3827247_10	1207063.P24_09591	2.386e-198	636.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2JQAX@204441|Rhodospirillales	204441|Rhodospirillales	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3827247_5	1095769.CAHF01000001_gene3463	7.369e-268	831.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,4735T@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
CMS1_k127_3827247_6	1095769.CAHF01000001_gene3462	6.127e-244	759.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,47348@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_3847829_21	1485544.JQKP01000002_gene1412	1.331e-45	168.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,44VSN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
CMS1_k127_3847829_1	265072.Mfla_0358	0.0	1183.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KM0Q@206350|Nitrosomonadales	206350|Nitrosomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_3847829_7	1123354.AUDR01000001_gene2015	2.414e-107	354.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,1KRBF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_3847829_18	288000.BBta_4490	1.395e-51	201.0	COG1011@1|root,COG1011@2|Bacteria,1PGNF@1224|Proteobacteria,2TWR1@28211|Alphaproteobacteria,3JRHW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Haloacid dehalogenase-like hydrolase	MA20_37750	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_3847829_24	1485544.JQKP01000002_gene1447	6.414e-18	87.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,44VZF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
CMS1_k127_3847829_6	323848.Nmul_A0565	1.088e-122	402.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,37292@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS1_k127_3847829_19	522306.CAP2UW1_1113	5.975e-49	184.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,1KQZ5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3847829_0	1123392.AQWL01000002_gene1972	0.0	1767.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,1KRD1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
CMS1_k127_3847829_22	1454004.AW11_00032	4.711e-44	164.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,1KQWG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	FG	HIT domain	hit	-	-	-	-	-	-	-	-	-	-	-	HIT
CMS1_k127_3847829_10	1163617.SCD_n00281	1.04e-97	342.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3847829_5	1485544.JQKP01000012_gene2133	1.976e-123	409.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,44VNZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	TIGRFAM phosphate regulon sensor kinase PhoR	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
CMS1_k127_3847829_9	640081.Dsui_0863	3.494e-106	348.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KUNU@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3847829_8	1123354.AUDR01000012_gene1867	3.577e-107	354.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,1KSN0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS1_k127_3847829_17	1454004.AW11_00028	1.628e-55	206.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,1KQPU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
CMS1_k127_3847829_23	795666.MW7_2276	8.191e-28	119.0	COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,1K2KU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Sterol-binding domain protein	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
CMS1_k127_3847829_2	864073.HFRIS_021536	1.796e-193	615.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,473XB@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_3847829_16	557598.LHK_01007	5.069e-56	201.0	COG2518@1|root,COG2518@2|Bacteria,1QWH0@1224|Proteobacteria,2WHXX@28216|Betaproteobacteria,2KU5B@206351|Neisseriales	206351|Neisseriales	O	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
CMS1_k127_3847829_3	1100720.ALKN01000030_gene1143	3.465e-179	573.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,4AAXN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
CMS1_k127_3847829_13	1304883.KI912532_gene873	3.928e-70	252.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,2KW9S@206389|Rhodocyclales	206389|Rhodocyclales	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS1_k127_3847829_20	1123256.KB907928_gene1969	6.766e-48	173.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,1X7ZG@135614|Xanthomonadales	135614|Xanthomonadales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
CMS1_k127_3847829_14	1286093.C266_04824	1.039e-64	228.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,1K1NE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
CMS1_k127_3847829_4	1485544.JQKP01000002_gene1427	1.79e-132	437.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
CMS1_k127_3847829_11	640081.Dsui_0720	8.77e-82	295.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,2KVIE@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
CMS1_k127_3847829_15	1266925.JHVX01000003_gene430	1.715e-62	230.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,3737C@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS1_k127_3847829_12	62928.azo3477	3.308e-80	276.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,2KV05@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CMS1_k127_3869686_1	316067.Geob_3322	3.535e-223	707.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.109.1,3.A.1.109.2,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CMS1_k127_3869686_4	1158292.JPOE01000005_gene217	1.822e-161	520.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VSBW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_3869686_5	1157708.KB907462_gene884	1.047e-155	522.0	COG0277@1|root,COG0277@2|Bacteria,1N4UQ@1224|Proteobacteria,2W1U4@28216|Betaproteobacteria,4AHE1@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
CMS1_k127_3869686_21	1163617.SCD_n00057	1.307e-25	109.0	2E1DK@1|root,32WSU@2|Bacteria,1N3VJ@1224|Proteobacteria,2VV0D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3869686_2	1288494.EBAPG3_3990	6.377e-215	694.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,372QC@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_3869686_8	62928.azo0937	5.562e-133	436.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,2KUII@206389|Rhodocyclales	206389|Rhodocyclales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CMS1_k127_3869686_23	1000565.METUNv1_00764	1.054e-18	86.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,2KX7Z@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
CMS1_k127_3869686_12	640081.Dsui_3134	1.402e-119	391.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,2KUAU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_3869686_6	1000565.METUNv1_00762	8.441e-155	498.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,2KUKU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS1_k127_3869686_9	883126.HMPREF9710_02123	7.678e-131	432.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,473MT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_3869686_19	1198452.Jab_2c19520	1.15e-35	137.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,474UU@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
CMS1_k127_3869686_3	62928.azo1036	5.864e-176	558.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,2KUQ4@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS1_k127_3869686_22	1238182.C882_1029	7.656e-22	100.0	2EB0P@1|root,3351I@2|Bacteria,1NAEB@1224|Proteobacteria,2UG0E@28211|Alphaproteobacteria,2JUS0@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3869686_7	322710.Avin_44030	6.577e-152	490.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CMS1_k127_3869686_10	887062.HGR_04393	4.747e-127	441.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,4AIFH@80864|Comamonadaceae	28216|Betaproteobacteria	P	Divalent cation transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_3869686_20	1122604.JONR01000006_gene2513	5.018e-34	137.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS1_k127_3869686_14	1123487.KB892863_gene1873	9.401e-90	304.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria,2KW3S@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3869686_18	420324.KI911961_gene1916	2.744e-42	160.0	COG2259@1|root,COG2259@2|Bacteria,1N06A@1224|Proteobacteria,2UB6H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_3869686_16	1123487.KB892863_gene1874	4.588e-77	278.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VIC3@28216|Betaproteobacteria,2KVN7@206389|Rhodocyclales	206389|Rhodocyclales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
CMS1_k127_3869686_17	1205680.CAKO01000040_gene808	2.952e-65	230.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3869686_0	292415.Tbd_0091	5.089e-240	754.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,1KRGZ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_3869686_15	1384054.N790_12970	2.794e-88	313.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
CMS1_k127_3869686_11	1163617.SCD_n00989	1.306e-119	389.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	abc transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_3869686_13	187272.Mlg_2775	4.503e-100	338.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales	135613|Chromatiales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS1_k127_3869686_24	1198452.Jab_1c20440	2.856e-09	58.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,4730X@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_3872093_0	1485544.JQKP01000003_gene117	0.0	1191.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,44W7T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_3872093_1	1265502.KB905931_gene1675	6.386e-32	125.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,4AAVY@80864|Comamonadaceae	28216|Betaproteobacteria	H	Molybdenum cofactor synthesis domain	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS1_k127_3957034_1	870187.Thini_2050	3.428e-56	221.0	2DMSB@1|root,32TC4@2|Bacteria,1R9F1@1224|Proteobacteria,1ST3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3957034_2	365044.Pnap_3592	1.174e-47	189.0	COG3121@1|root,COG3121@2|Bacteria,1R5EM@1224|Proteobacteria,2W1K7@28216|Betaproteobacteria,4AGKA@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3957034_5	84531.JMTZ01000064_gene1862	1.255e-08	63.0	2BWJI@1|root,3434Y@2|Bacteria,1NZ1E@1224|Proteobacteria,1T8B8@1236|Gammaproteobacteria,1XAD3@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3957034_4	1384056.N787_05450	1.504e-09	67.0	2C39A@1|root,3250C@2|Bacteria,1PX8W@1224|Proteobacteria,1T8YG@1236|Gammaproteobacteria,1XBE7@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3957034_6	1384056.N787_05450	2.232e-07	60.0	2C39A@1|root,3250C@2|Bacteria,1PX8W@1224|Proteobacteria,1T8YG@1236|Gammaproteobacteria,1XBE7@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3957034_0	865861.AZSU01000005_gene826	2.802e-65	234.0	COG1712@1|root,COG1712@2|Bacteria,1UZUW@1239|Firmicutes,24JQ3@186801|Clostridia	186801|Clostridia	S	Domain of unknown function DUF108	-	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
CMS1_k127_3957034_3	522306.CAP2UW1_3495	3.554e-19	87.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,1KPWG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_3979811_3	1485544.JQKP01000005_gene320	1.403e-198	626.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,44V9S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
CMS1_k127_3979811_23	292415.Tbd_2476	6.005e-36	144.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3979811_10	580332.Slit_1676	1.725e-102	347.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44W6H@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
CMS1_k127_3979811_5	292415.Tbd_2474	3.061e-157	507.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,2VK76@28216|Betaproteobacteria,1KSUI@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS1_k127_3979811_4	292415.Tbd_2473	9.02e-173	573.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,1KRQV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	CobB/CobQ-like glutamine amidotransferase domain	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,GATase_3
CMS1_k127_3979811_6	1163617.SCD_n02704	6.014e-150	490.0	COG1249@1|root,COG1249@2|Bacteria,1RB5F@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpdA_2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_3979811_14	765912.Thimo_3548	7.955e-89	312.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria,1WZX3@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3979811_16	292415.Tbd_2464	2.787e-75	258.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1KSM0@119069|Hydrogenophilales	119069|Hydrogenophilales	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_3979811_11	1163617.SCD_n00343	2.545e-102	347.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
CMS1_k127_3979811_22	1500894.JQNN01000001_gene1939	2.006e-38	166.0	COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,2WGNF@28216|Betaproteobacteria,473IV@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
CMS1_k127_3979811_30	316067.Geob_1015	1.559e-18	97.0	2EE9W@1|root,3384B@2|Bacteria,1NCE1@1224|Proteobacteria,42VUH@68525|delta/epsilon subdivisions,2WSA1@28221|Deltaproteobacteria,43V30@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
CMS1_k127_3979811_25	28229.ND2E_2955	1.557e-30	134.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Cytochrome c	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_3979811_15	589924.Ferp_1438	1.038e-84	289.0	COG0437@1|root,arCOG01500@2157|Archaea,2XXPU@28890|Euryarchaeota,24691@183980|Archaeoglobi	183980|Archaeoglobi	C	4Fe-4S dicluster domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4,Fer4_11
CMS1_k127_3979811_13	1379698.RBG1_1C00001G0297	3.651e-94	323.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
CMS1_k127_3979811_29	553385.JEMF01000021_gene3070	1.57e-19	102.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales	135619|Oceanospirillales	C	COG2863 Cytochrome c553	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_3979811_27	391615.ABSJ01000033_gene698	8.208e-24	115.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,1SBJR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_3979811_21	1283300.ATXB01000001_gene227	6.776e-48	181.0	293CN@1|root,2Z9VJ@2|Bacteria,1MXNG@1224|Proteobacteria,1RZCQ@1236|Gammaproteobacteria,1XDMH@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3979811_20	159087.Daro_3859	2.18e-48	189.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,2KWMI@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_3979811_26	702113.PP1Y_AT23279	2.151e-24	117.0	2E92Z@1|root,333BY@2|Bacteria,1N8J4@1224|Proteobacteria,2UI81@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3979811_28	589865.DaAHT2_0247	3.762e-23	102.0	28XS9@1|root,2ZJNQ@2|Bacteria	2|Bacteria	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS1_k127_3979811_1	1163617.SCD_n02745	1.699e-228	726.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3979811_24	1535422.ND16A_2692	3.252e-33	144.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Cytochrome c	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_3979811_9	880073.Calab_3717	3.607e-114	385.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
CMS1_k127_3979811_2	398767.Glov_2292	5.785e-202	659.0	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,42VEM@68525|delta/epsilon subdivisions,2WRGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3979811_7	1121920.AUAU01000008_gene1597	3.525e-144	486.0	2DBW6@1|root,2ZBEP@2|Bacteria,3Y9F1@57723|Acidobacteria	2|Bacteria	C	TIGRFAM decaheme c-type cytochrome, OmcA MtrC family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
CMS1_k127_3979811_12	1283300.ATXB01000002_gene2887	3.77e-98	329.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
CMS1_k127_3979811_8	1283300.ATXB01000002_gene2886	5.94e-139	466.0	COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
CMS1_k127_3979811_19	1279038.KB907348_gene3100	4.48e-54	203.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_3979811_17	1380394.JADL01000003_gene5118	4.424e-64	223.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2JSBG@204441|Rhodospirillales	204441|Rhodospirillales	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
CMS1_k127_3979811_0	1538295.JY96_15065	2.097e-242	773.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KJ3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein	iorB2	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS1_k127_3979811_18	85643.Tmz1t_2738	1.237e-56	206.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,2WFVG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
CMS1_k127_3990705_13	394.NGR_c19210	4.791e-46	176.0	COG1357@1|root,COG1357@2|Bacteria,1MZMI@1224|Proteobacteria,2UDCV@28211|Alphaproteobacteria,4B8YC@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
CMS1_k127_3990705_2	269482.Bcep1808_1836	4.067e-190	599.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,1K03I@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_3990705_0	1235457.C404_10485	2.403e-288	901.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,1JZX3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-coa dehydrogenase	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_3990705_7	1265502.KB905969_gene1232	2.154e-130	429.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2VHK0@28216|Betaproteobacteria,4A9P3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Malonyl-CoA decarboxylase	matA	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
CMS1_k127_3990705_9	1265502.KB905940_gene3000	3.337e-105	348.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VINK@28216|Betaproteobacteria,4A9WA@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_3990705_8	402626.Rpic_1451	8.904e-111	374.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VIKW@28216|Betaproteobacteria,1JZVH@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_3990705_3	388051.AUFE01000030_gene5076	6.583e-159	511.0	COG4177@1|root,COG4177@2|Bacteria,1MY3V@1224|Proteobacteria,2VJIE@28216|Betaproteobacteria,1K0XJ@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
CMS1_k127_3990705_6	688245.CtCNB1_2958	1.607e-130	423.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VJAM@28216|Betaproteobacteria,4AANH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_3990705_5	977880.RALTA_A1461	3.268e-132	435.0	COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2VI1S@28216|Betaproteobacteria,1K1YI@119060|Burkholderiaceae	28216|Betaproteobacteria	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_3990705_15	637389.Acaty_c2456	8.086e-14	74.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,2NCJH@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
CMS1_k127_3990705_1	987059.RBXJA2T_04138	2.626e-253	791.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,1KIY7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3990705_11	1286093.C266_06629	4.388e-79	274.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2VJC1@28216|Betaproteobacteria,1JZXT@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_3990705_12	1158292.JPOE01000002_gene2084	2.088e-76	276.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2VJ9I@28216|Betaproteobacteria,1KKZS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3990705_14	1173027.Mic7113_5685	2.321e-42	162.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria,1HI3B@1150|Oscillatoriales	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3990705_10	1123368.AUIS01000004_gene120	1.893e-86	315.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria,2NDJ6@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
CMS1_k127_3990705_4	1336235.JAEG01000020_gene3457	9.691e-149	483.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria,4B7C3@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_4001046_37	338969.Rfer_2484	6.798e-79	271.0	28NPW@1|root,2ZBPM@2|Bacteria,1RAMG@1224|Proteobacteria,2VQIF@28216|Betaproteobacteria,4AE6G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4001046_0	338969.Rfer_2485	2.5e-323	1018.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,4AD7T@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
CMS1_k127_4001046_49	1163617.SCD_n00996	2.566e-40	151.0	COG2920@1|root,COG2920@2|Bacteria,1N3YM@1224|Proteobacteria,2W3KZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS1_k127_4001046_14	426114.THI_3126	8.949e-135	449.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2VHX5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_4001046_20	1163617.SCD_n01435	4.609e-108	355.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria	28216|Betaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4001046_45	1232410.KI421422_gene1959	3.546e-51	186.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,42U27@68525|delta/epsilon subdivisions,2WR2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_4001046_50	1333998.M2A_3303	3.649e-40	160.0	COG1051@1|root,COG1051@2|Bacteria,1QU5T@1224|Proteobacteria,2TW0R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_4001046_2	1000565.METUNv1_01897	1.439e-278	875.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,2KUTU@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS1_k127_4001046_36	472759.Nhal_0303	3.288e-79	267.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,1S1HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_4001046_30	279714.FuraDRAFT_1484	3.846e-90	302.0	COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2WEV9@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N_3
CMS1_k127_4001046_55	1163409.UUA_18319	1.247e-24	108.0	COG1733@1|root,COG1733@2|Bacteria,1N0WJ@1224|Proteobacteria,1SYZ9@1236|Gammaproteobacteria,1X8VM@135614|Xanthomonadales	135614|Xanthomonadales	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS1_k127_4001046_10	864069.MicloDRAFT_00067060	6.904e-160	511.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,1JT5Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
CMS1_k127_4001046_39	1123073.KB899242_gene1191	2.418e-75	275.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1RPWM@1236|Gammaproteobacteria,1X7FR@135614|Xanthomonadales	135614|Xanthomonadales	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
CMS1_k127_4001046_28	1313172.YM304_29050	3.479e-95	317.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CNTU@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_4001046_23	1144275.COCOR_01290	3.784e-103	342.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YY4M@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_4001046_6	1336243.JAEA01000010_gene3537	1.341e-187	606.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TS3K@28211|Alphaproteobacteria,1JRKY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_4001046_1	1458357.BG58_16140	1.121e-278	871.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,2VK0V@28216|Betaproteobacteria,1K123@119060|Burkholderiaceae	28216|Betaproteobacteria	E	3-isopropylmalate dehydratase	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_4001046_8	556268.OFAG_02107	1.999e-184	619.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria,478EE@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_4001046_27	497321.C664_16190	2.474e-99	334.0	COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria,2WFIE@28216|Betaproteobacteria,2KVF6@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
CMS1_k127_4001046_16	443143.GM18_1310	4.057e-126	423.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria	2|Bacteria	QT	Acyl-homoserine-lactone synthase	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AIRS,Acetyltransf_10,Acetyltransf_5,Aminotran_5
CMS1_k127_4001046_17	1163617.SCD_n00422	1.956e-123	407.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_4001046_34	675635.Psed_4311	2.847e-80	278.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4E3ZP@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_4001046_3	378806.STAUR_6282	3.193e-256	797.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2YU8Q@29|Myxococcales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS1_k127_4001046_7	395494.Galf_2643	3.189e-185	589.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,44VJJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_4001046_32	1123367.C666_04045	1.374e-84	289.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,2KUY8@206389|Rhodocyclales	206389|Rhodocyclales	M	acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS1_k127_4001046_25	305700.B447_19829	4.116e-100	347.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,2KVIC@206389|Rhodocyclales	206389|Rhodocyclales	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS1_k127_4001046_46	292415.Tbd_2525	1.005e-45	171.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	coa-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS1_k127_4001046_19	1485544.JQKP01000012_gene2121	1.141e-115	385.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,44V70@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS1_k127_4001046_41	62928.azo0595	1.933e-60	227.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,2KV4A@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
CMS1_k127_4001046_29	395494.Galf_2688	9.341e-94	316.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_4001046_12	1163617.SCD_n02069	1.172e-141	459.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_4001046_21	395019.Bmul_3500	1.266e-107	357.0	COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,2VKIK@28216|Betaproteobacteria,1K0KC@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	garR	-	1.1.1.31,1.1.1.411	ko:K00020,ko:K08319	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_4001046_9	1175306.GWL_36240	2.082e-168	539.0	COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,2VI5S@28216|Betaproteobacteria,4764D@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative nucleotide-binding of sugar-metabolising enzyme	hop	-	2.7.1.217	ko:K21948	-	-	R11706,R11707	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
CMS1_k127_4001046_33	1380394.JADL01000008_gene3523	5.419e-82	297.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2TSX7@28211|Alphaproteobacteria,2JRUR@204441|Rhodospirillales	204441|Rhodospirillales	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.1.104	ko:K22130	-	-	-	-	ko00000,ko01000	-	-	-	Aldolase_II
CMS1_k127_4001046_15	395019.Bmul_3496	2.66e-127	415.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,1K048@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the hyi family	hyi2	-	5.3.1.22,5.3.1.35	ko:K01816,ko:K22131	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_4001046_26	261292.Nit79A3_3271	1.491e-99	332.0	28JXP@1|root,2Z9N4@2|Bacteria,1MXG4@1224|Proteobacteria,2WBED@28216|Betaproteobacteria,372YW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CMS1_k127_4001046_38	1163617.SCD_n01782	5.61e-77	280.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS1_k127_4001046_48	1038859.AXAU01000004_gene4435	2.862e-43	161.0	COG1917@1|root,COG1917@2|Bacteria,1RB4Y@1224|Proteobacteria,2U5J9@28211|Alphaproteobacteria,3JYFC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin domain	MA20_40115	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_4001046_11	887898.HMPREF0551_2342	2.686e-143	461.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria,1K1R3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	yjiA_1	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
CMS1_k127_4001046_31	62928.azo0423	8.506e-85	287.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,2KUW6@206389|Rhodocyclales	206389|Rhodocyclales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS1_k127_4001046_4	1123487.KB892834_gene3057	2.661e-210	672.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,2KVM8@206389|Rhodocyclales	206389|Rhodocyclales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS1_k127_4001046_57	76114.ebD82	8.822e-10	64.0	2DRVR@1|root,33DAW@2|Bacteria,1NJ5A@1224|Proteobacteria,2WDK2@28216|Betaproteobacteria,2KZK5@206389|Rhodocyclales	206389|Rhodocyclales	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
CMS1_k127_4001046_56	267608.RSc0035	2.747e-12	70.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2WDYY@28216|Betaproteobacteria,1KBA2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_4001046_43	1454004.AW11_00672	5.308e-55	198.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4001046_52	292415.Tbd_2312	2.416e-38	153.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_4001046_13	1000565.METUNv1_02906	2.312e-140	450.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,2KVGB@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS1_k127_4001046_40	1304883.KI912532_gene1430	3.021e-65	248.0	COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,2KW3U@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyrimidine 5''-nucleotidase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_4001046_42	987059.RBXJA2T_06885	1.493e-58	220.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,1KK77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
CMS1_k127_4001046_22	1000565.METUNv1_02932	3.43e-103	342.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,2KUF5@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_4001046_5	640081.Dsui_1270	7.954e-191	605.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,2KUHV@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS1_k127_4001046_35	1121035.AUCH01000005_gene164	2.96e-80	283.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,2KV1S@206389|Rhodocyclales	206389|Rhodocyclales	D	peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_4001046_18	535289.Dtpsy_2828	6.173e-122	395.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,4AAD1@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS1_k127_4001046_47	292415.Tbd_2395	2.482e-45	168.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,1KT6W@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_4001046_51	1121035.AUCH01000005_gene166	1.801e-38	147.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KWVI@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_4001046_54	760117.JN27_21595	5.793e-28	117.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,474TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
CMS1_k127_4001046_44	1236959.BAMT01000002_gene2222	1.589e-51	187.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,2KMSR@206350|Nitrosomonadales	206350|Nitrosomonadales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
CMS1_k127_4001046_53	62928.azo2813	1.469e-34	144.0	COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria,2KWXG@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
CMS1_k127_4001046_24	323848.Nmul_A1126	6.15e-101	342.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,371NF@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS1_k127_4026403_3	1038862.KB893862_gene2254	7.04e-43	160.0	COG0627@1|root,COG0627@2|Bacteria,1MX6W@1224|Proteobacteria,2TSCC@28211|Alphaproteobacteria,3K6P2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.1.102	ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	Tannase
CMS1_k127_4026403_0	870187.Thini_2540	3.862e-137	449.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,460KI@72273|Thiotrichales	72273|Thiotrichales	P	Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085)	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS1_k127_4026403_4	1211115.ALIQ01000183_gene2912	6.116e-28	115.0	COG5470@1|root,COG5470@2|Bacteria,1N012@1224|Proteobacteria,2VG1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_4026403_2	1282876.BAOK01000001_gene3492	1.441e-59	216.0	28P9J@1|root,2ZC30@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4026403_1	330214.NIDE0014	9.478e-134	441.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_4026403_5	1510531.JQJJ01000009_gene510	6.234e-20	90.0	COG0412@1|root,COG0412@2|Bacteria,1R9JT@1224|Proteobacteria,2U4J1@28211|Alphaproteobacteria,3JWZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_4097343_1	62928.azo2158	3.603e-111	368.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KVJB@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CMS1_k127_4097343_2	159087.Daro_2001	5.486e-11	77.0	COG2982@1|root,COG2982@2|Bacteria,1RD61@1224|Proteobacteria,2VS09@28216|Betaproteobacteria,2KWG8@206389|Rhodocyclales	206389|Rhodocyclales	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
CMS1_k127_4097343_0	94624.Bpet2239	2.252e-257	800.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,3T1HA@506|Alcaligenaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS1_k127_4183977_1	204669.Acid345_3213	2.486e-83	283.0	COG0563@1|root,COG0563@2|Bacteria,3Y421@57723|Acidobacteria,2JI14@204432|Acidobacteriia	57723|Acidobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_4183977_0	316067.Geob_3189	3.201e-128	427.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,42TBM@68525|delta/epsilon subdivisions,2WP92@28221|Deltaproteobacteria,43V6A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
CMS1_k127_4183977_2	159087.Daro_1096	2.543e-52	195.0	COG0477@1|root,COG2814@2|Bacteria,1PE5A@1224|Proteobacteria,2VHTJ@28216|Betaproteobacteria,2KXRW@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4226135_3	887898.HMPREF0551_2295	6.484e-59	208.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2WGIZ@28216|Betaproteobacteria,1KIKX@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Major Facilitator	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
CMS1_k127_4226135_1	1037409.BJ6T_56240	3.627e-128	439.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc,Hydrolase_4,Trans_reg_C
CMS1_k127_4226135_2	1163617.SCD_n00087	1.434e-73	258.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2VMPA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
CMS1_k127_4226135_0	62928.azo3971	2.014e-183	581.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,2KVER@206389|Rhodocyclales	206389|Rhodocyclales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_4226135_4	331869.BAL199_20860	3.581e-41	163.0	COG4122@1|root,COG4122@2|Bacteria,1NG6W@1224|Proteobacteria,2UM77@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
CMS1_k127_4300926_1	983917.RGE_30570	7.602e-126	417.0	COG2010@1|root,COG2010@2|Bacteria,1R1VN@1224|Proteobacteria,2WI66@28216|Betaproteobacteria,1KN79@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS1_k127_4300926_0	983917.RGE_30580	2.666e-145	472.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2WEME@28216|Betaproteobacteria,1KN2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_4300926_2	85643.Tmz1t_0618	3.623e-48	178.0	COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria,2WGTA@28216|Betaproteobacteria,2KZWK@206389|Rhodocyclales	206389|Rhodocyclales	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4382305_73	62928.azo0531	5.406e-17	82.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria,2KXU7@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
CMS1_k127_4382305_6	1163617.SCD_n00031	1.052e-255	805.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
CMS1_k127_4382305_69	748280.NH8B_4001	1.801e-34	135.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KRVU@206351|Neisseriales	206351|Neisseriales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_4382305_29	522306.CAP2UW1_3612	4.353e-127	420.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,1KQBE@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_4382305_34	1454004.AW11_00402	1.709e-119	392.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KQHA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_4382305_23	522306.CAP2UW1_3610	1.807e-150	499.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,1KQDQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_4382305_36	1216976.AX27061_3879	1.814e-107	371.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,3T22A@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_4382305_44	75379.Tint_2409	8.061e-79	283.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,1KJ0T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_4382305_22	1095769.CAHF01000013_gene3192	1.257e-154	494.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,47360@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS1_k127_4382305_41	305700.B447_11522	5.28e-87	295.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,2KUSE@206389|Rhodocyclales	206389|Rhodocyclales	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_4382305_67	1454004.AW11_02138	5.881e-38	148.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,1KR5M@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CMS1_k127_4382305_14	640081.Dsui_0718	1.644e-186	606.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,2KV4F@206389|Rhodocyclales	206389|Rhodocyclales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS1_k127_4382305_21	75379.Tint_0292	2.775e-158	506.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,1KJ96@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS1_k127_4382305_51	1123367.C666_02020	1.905e-56	205.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,2KVVZ@206389|Rhodocyclales	206389|Rhodocyclales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS1_k127_4382305_46	640081.Dsui_1304	3.842e-70	243.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,2KUPA@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_4382305_31	1123368.AUIS01000035_gene72	3.346e-124	414.0	COG1249@1|root,COG1249@2|Bacteria,1RB5F@1224|Proteobacteria,1S51N@1236|Gammaproteobacteria,2NCNT@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_4382305_59	1123261.AXDW01000003_gene1811	2.277e-49	186.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S6CS@1236|Gammaproteobacteria,1X7K7@135614|Xanthomonadales	135614|Xanthomonadales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_4382305_72	452638.Pnec_1340	2.827e-25	113.0	COG3909@1|root,COG3909@2|Bacteria,1N1E5@1224|Proteobacteria,2VSGD@28216|Betaproteobacteria,1KE9B@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome C'	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
CMS1_k127_4382305_57	640511.BC1002_3785	1.008e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria,1K1I0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE8	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4382305_45	1163617.SCD_n00185	3.438e-70	246.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	prtR	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_4382305_27	1472716.KBK24_0113335	3.071e-134	435.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,1K19W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CMS1_k127_4382305_47	1123392.AQWL01000002_gene1981	3.952e-70	244.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,1KSU5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
CMS1_k127_4382305_43	580332.Slit_2572	2.03e-84	288.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4382305_28	1007105.PT7_0956	4.088e-133	435.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2W0AM@28216|Betaproteobacteria,3T617@506|Alcaligenaceae	28216|Betaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_4382305_32	1163617.SCD_n00016	1.694e-121	401.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS1_k127_4382305_17	977880.RALTA_B0384	2.242e-182	584.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VH34@28216|Betaproteobacteria,1KFIP@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
CMS1_k127_4382305_2	1123073.KB899243_gene459	0.0	1267.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3JU@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS1_k127_4382305_39	880072.Desac_1403	1.159e-93	320.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,2MR7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_4382305_20	305700.B447_16784	1.143e-162	527.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,2KVC9@206389|Rhodocyclales	206389|Rhodocyclales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_4382305_68	1454004.AW11_02621	5.693e-37	145.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,1KQ5H@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Inorganic ion transport and metabolism	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
CMS1_k127_4382305_3	640081.Dsui_1186	7.69e-305	953.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS1_k127_4382305_24	1454004.AW11_03349	7.98e-147	473.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS1_k127_4382305_52	1163617.SCD_n02942	2.218e-56	205.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
CMS1_k127_4382305_48	522306.CAP2UW1_4187	1.11e-67	236.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
CMS1_k127_4382305_63	640081.Dsui_1190	6.443e-45	170.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria,2KWK4@206389|Rhodocyclales	206389|Rhodocyclales	NU	pilus assembly protein PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
CMS1_k127_4382305_7	420662.Mpe_A3109	1.135e-241	766.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,1KJSP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS1_k127_4382305_50	266264.Rmet_3267	4.317e-60	212.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,1K1DP@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS1_k127_4382305_26	76114.ebA2256	2.448e-135	449.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,2KURZ@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS1_k127_4382305_0	1095769.CAHF01000003_gene1017	0.0	2353.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,4723Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_4382305_8	93220.LV28_12665	7.735e-241	752.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,1K273@119060|Burkholderiaceae	28216|Betaproteobacteria	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS1_k127_4382305_19	1437824.BN940_02076	1.742e-169	544.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,3T1X3@506|Alcaligenaceae	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
CMS1_k127_4382305_4	522306.CAP2UW1_4175	8.61e-271	844.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,1KPQ7@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS1_k127_4382305_33	1316936.K678_12187	1.739e-120	416.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JRBS@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
CMS1_k127_4382305_58	1244869.H261_12176	2.782e-50	183.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria,2JSX2@204441|Rhodospirillales	204441|Rhodospirillales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_4382305_70	187272.Mlg_0695	4.777e-31	138.0	COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,1S85V@1236|Gammaproteobacteria,1WZFW@135613|Chromatiales	135613|Chromatiales	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_4382305_30	85643.Tmz1t_2956	6.748e-126	427.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,2KY5Y@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_4382305_10	85643.Tmz1t_2955	1.262e-220	700.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,2KY1I@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
CMS1_k127_4382305_16	648757.Rvan_0035	3.855e-184	581.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_4382305_40	85643.Tmz1t_2952	4.08e-92	325.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	dch	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_4382305_18	1232410.KI421421_gene3270	6.355e-171	559.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS1_k127_4382305_11	85643.Tmz1t_2950	1.124e-212	667.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2W3EH@28216|Betaproteobacteria,2KZ1E@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS1_k127_4382305_15	1187851.A33M_3198	2.879e-186	595.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
CMS1_k127_4382305_35	648757.Rvan_0040	1.069e-110	378.0	COG1924@1|root,COG1924@2|Bacteria,1MY0N@1224|Proteobacteria,2U4V9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
CMS1_k127_4382305_65	316056.RPC_1024	1.39e-38	145.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2UG0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS1_k127_4382305_42	1117314.PCIT_03558	6.201e-85	293.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,2Q1CS@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Outer membrane phospholipase A	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
CMS1_k127_4382305_49	1244869.H261_21688	1.289e-62	235.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4382305_12	1380394.JADL01000002_gene1594	1.483e-197	625.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,2JQ5N@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_4382305_55	62928.azo1948	6.896e-54	208.0	COG3302@1|root,COG3302@2|Bacteria,1N8SU@1224|Proteobacteria,2WGE7@28216|Betaproteobacteria,2M04N@206389|Rhodocyclales	206389|Rhodocyclales	S	DMSO reductase anchor subunit (DmsC)	-	-	-	ko:K18363	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	DmsC
CMS1_k127_4382305_37	62928.azo1947	1.661e-106	374.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,2KXUS@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	ko:K18362	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	-
CMS1_k127_4382305_1	85643.Tmz1t_2959	0.0	1302.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.5.1,3.1.2.25	ko:K18361	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
CMS1_k127_4382305_62	1380394.JADL01000002_gene1592	1.891e-45	169.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria,2JUEU@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4382305_61	1000565.METUNv1_02075	1.309e-46	177.0	COG3707@1|root,COG3707@2|Bacteria,1QZ0F@1224|Proteobacteria,2WHZP@28216|Betaproteobacteria	28216|Betaproteobacteria	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
CMS1_k127_4382305_9	1223521.BBJX01000007_gene1437	3.699e-238	772.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,Response_reg
CMS1_k127_4382305_66	1219077.VAZ01S_044_00260	3.849e-38	149.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,1XXAG@135623|Vibrionales	135623|Vibrionales	C	Ferredoxin	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS1_k127_4382305_25	1123255.JHYS01000005_gene652	6.06e-140	453.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,4AA11@80864|Comamonadaceae	28216|Betaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB2	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS1_k127_4382305_54	75379.Tint_1226	5.462e-55	198.0	COG1871@1|root,COG1871@2|Bacteria,1RI55@1224|Proteobacteria,2VUAC@28216|Betaproteobacteria,1KM2R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
CMS1_k127_4382305_38	1282356.H045_08265	4.978e-102	342.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1YSX9@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR2	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS1_k127_4382305_53	395494.Galf_1971	3.212e-55	199.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2VRAI@28216|Betaproteobacteria,44WEW@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	SMART CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS1_k127_4382305_13	864051.BurJ1DRAFT_0850	1.358e-186	610.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KJZW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,PAS_9
CMS1_k127_4382305_5	62928.azo0408	3.105e-259	818.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVQE@206389|Rhodocyclales	206389|Rhodocyclales	T	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS1_k127_4382305_71	395494.Galf_1974	2.838e-26	111.0	COG3113@1|root,COG3113@2|Bacteria,1NI22@1224|Proteobacteria	1224|Proteobacteria	S	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
CMS1_k127_4382305_60	1038922.PflQ2_2034	1.343e-47	174.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1YTK0@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	KT	Protein involved in kinase activity, two-component response regulator activity, chemotaxis, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent	IV02_18015	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS1_k127_4382305_56	1448139.AI20_14105	1.694e-52	203.0	COG0840@1|root,COG0840@2|Bacteria,1NCMF@1224|Proteobacteria,1RRP8@1236|Gammaproteobacteria,1Y5UK@135624|Aeromonadales	135624|Aeromonadales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
CMS1_k127_4382305_64	497964.CfE428DRAFT_3582	1.569e-43	161.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
CMS1_k127_4400759_2	93220.LV28_12450	3.497e-125	422.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1K08M@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS1_k127_4400759_10	1348657.M622_03410	5.76e-78	268.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,2KVZE@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
CMS1_k127_4400759_1	1304883.KI912532_gene1676	3.693e-150	484.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,2KV5H@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_4400759_6	76114.ebA1285	1.622e-103	343.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,2KUWA@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS1_k127_4400759_15	748247.AZKH_0765	8.209e-30	124.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_4400759_16	522306.CAP2UW1_4042	3.774e-24	103.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,1KR3F@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_4400759_12	522306.CAP2UW1_4041	4.987e-44	169.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,1KQ3Q@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	FG	Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
CMS1_k127_4400759_13	666681.M301_0310	2.24e-33	141.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,2KMX7@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
CMS1_k127_4400759_11	1112217.PPL19_16285	2.428e-54	203.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_5014	PRA-CH,PRA-PH
CMS1_k127_4400759_3	522306.CAP2UW1_4038	8.873e-125	416.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,1KPRR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_4400759_5	76114.ebA1293	1.303e-114	375.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,2KUM6@206389|Rhodocyclales	206389|Rhodocyclales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_4400759_9	1304883.KI912532_gene1666	2.13e-93	310.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,2KUCS@206389|Rhodocyclales	206389|Rhodocyclales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_4400759_8	1005048.CFU_0517	1.699e-98	340.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,473JG@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS1_k127_4400759_4	93220.LV28_12540	3.206e-121	404.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,1K1VS@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_4400759_0	557598.LHK_00184	4.586e-184	596.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,2KPF7@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS1_k127_4400759_7	1120999.JONM01000010_gene4139	1.143e-101	336.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,2KQ9A@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
CMS1_k127_4400759_14	1144319.PMI16_03438	1.915e-30	126.0	2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria,2VUGJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2846
CMS1_k127_441099_1	582744.Msip34_0969	7.035e-23	98.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2VH6D@28216|Betaproteobacteria,2KM8N@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS1_k127_441099_0	1095769.CAHF01000014_gene2999	0.0	1594.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,472T4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
CMS1_k127_4466576_2	1190603.AJYD01000015_gene947	1.302e-85	291.0	COG1653@1|root,COG1653@2|Bacteria,1MX9J@1224|Proteobacteria,1RPYT@1236|Gammaproteobacteria,1XUUS@135623|Vibrionales	135623|Vibrionales	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10236	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	SBP_bac_1
CMS1_k127_4466576_0	1411123.JQNH01000001_gene502	5.319e-163	529.0	COG2358@1|root,COG2358@2|Bacteria,1R3ZR@1224|Proteobacteria,2TSND@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system periplasmic component	MA20_27285	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
CMS1_k127_4466576_1	1381123.AYOD01000014_gene2248	2.377e-135	443.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,43I4Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_4511489_0	1485544.JQKP01000004_gene505	3.748e-201	651.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
CMS1_k127_4511489_4	365046.Rta_19360	2.321e-71	250.0	COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,2VVI5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	plastoquinol--plastocyanin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4511489_3	1163617.SCD_n01859	2.618e-83	294.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS1_k127_4511489_1	497321.C664_06698	7.355e-104	343.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CMS1_k127_4511489_2	76114.ebA4888	4.608e-102	338.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,2KVCI@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_4517322_9	1215092.PA6_004_00670	5.653e-90	306.0	COG0604@1|root,COG0604@2|Bacteria,1MXCV@1224|Proteobacteria,1S13Q@1236|Gammaproteobacteria,1YCZ2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4517322_2	1123504.JQKD01000027_gene4088	4.247e-173	553.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2VIUC@28216|Betaproteobacteria,4AC4C@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS1_k127_4517322_14	1121937.AUHJ01000002_gene3569	2.319e-39	148.0	COG5470@1|root,COG5470@2|Bacteria,1NC8B@1224|Proteobacteria,1SCBU@1236|Gammaproteobacteria,46BHN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_4517322_3	1082933.MEA186_18517	8.395e-157	506.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2TT55@28211|Alphaproteobacteria,43JJ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	soxF	-	1.8.2.3,1.8.5.4	ko:K17218,ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499,R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
CMS1_k127_4517322_4	614083.AWQR01000014_gene2485	1.297e-112	368.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2VMG6@28216|Betaproteobacteria,4ABN6@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_4517322_16	1089439.KB902239_gene506	6.417e-08	56.0	2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4517322_15	1380391.JIAS01000018_gene1006	9.95e-15	78.0	COG1359@1|root,COG1359@2|Bacteria,1N98F@1224|Proteobacteria,2UFXS@28211|Alphaproteobacteria,2JZTZ@204441|Rhodospirillales	204441|Rhodospirillales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_4517322_11	1297865.APJD01000005_gene3597	2.173e-48	184.0	COG1853@1|root,COG1853@2|Bacteria,1MXPE@1224|Proteobacteria,2TS7H@28211|Alphaproteobacteria,3JSXQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Flavin reductase like domain	MA20_16400	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_4517322_12	331869.BAL199_14217	3.033e-45	186.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	barA	-	2.7.13.3	ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7
CMS1_k127_4517322_17	864051.BurJ1DRAFT_3375	6.64e-08	66.0	COG3437@1|root,COG3437@2|Bacteria,1PDX2@1224|Proteobacteria,2VMIS@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
CMS1_k127_4517322_10	887062.HGR_04818	3.798e-51	187.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,2VX5P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
CMS1_k127_4517322_1	887062.HGR_04823	3.211e-181	591.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CMS1_k127_4517322_7	887062.HGR_04828	1.379e-92	320.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,2WERU@28216|Betaproteobacteria,4AF1F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS1_k127_4517322_13	1205680.CAKO01000042_gene5424	4.573e-40	154.0	COG1853@1|root,COG1853@2|Bacteria,1NESS@1224|Proteobacteria,2U94D@28211|Alphaproteobacteria,2JX21@204441|Rhodospirillales	204441|Rhodospirillales	S	Flavin reductase like domain	-	-	-	ko:K09024	ko00240,ko01100,map00240,map01100	-	R09936	RC02732	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
CMS1_k127_4517322_8	1235457.C404_21215	3.988e-91	308.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2VNEM@28216|Betaproteobacteria,1K5AJ@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4517322_0	580332.Slit_1506	2.639e-197	624.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,44VDU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_4517322_6	314271.RB2654_18041	1.137e-104	356.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TRAP transporter solute receptor TAXI family protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_4517322_5	314271.RB2654_18046	9.928e-108	354.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_4542701_12	580332.Slit_1396	1.066e-27	116.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,44UYC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS1_k127_4542701_10	398767.Glov_3532	3.245e-52	190.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	DsbA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_4542701_13	596154.Alide2_3778	2.806e-15	90.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,4AA8Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS1_k127_4542701_4	522306.CAP2UW1_1058	1.569e-109	378.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2VH81@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha beta hydrolase	phaY2	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_4542701_15	911239.CF149_02574	2.634e-07	63.0	COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,1S2QD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LprI,MliC
CMS1_k127_4542701_6	1217718.ALOU01000019_gene2865	2.066e-94	316.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2VIMK@28216|Betaproteobacteria,1JZX0@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Nicotinamidase	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
CMS1_k127_4542701_5	472759.Nhal_3098	4.367e-109	368.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS1_k127_4542701_3	338969.Rfer_0482	4.156e-140	456.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,4ABHM@80864|Comamonadaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS1_k127_4542701_8	1380391.JIAS01000015_gene179	6.877e-67	250.0	COG3467@1|root,COG3467@2|Bacteria,1MWQE@1224|Proteobacteria,2TR7J@28211|Alphaproteobacteria,2JS97@204441|Rhodospirillales	204441|Rhodospirillales	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS1_k127_4542701_1	1205680.CAKO01000037_gene1234	3.712e-157	507.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2JPY3@204441|Rhodospirillales	204441|Rhodospirillales	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_4542701_7	1230343.CANP01000001_gene4	6.313e-70	252.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_4542701_2	1122603.ATVI01000005_gene3040	2.027e-153	496.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_4542701_11	1122603.ATVI01000005_gene3041	4.576e-47	180.0	COG2239@1|root,COG2239@2|Bacteria,1NNAQ@1224|Proteobacteria,1SHM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
CMS1_k127_4542701_9	1122603.ATVI01000005_gene3042	1.212e-64	232.0	COG0668@1|root,COG0668@2|Bacteria,1N4UN@1224|Proteobacteria,1T9TX@1236|Gammaproteobacteria,1XBUR@135614|Xanthomonadales	135614|Xanthomonadales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
CMS1_k127_4542701_0	713586.KB900536_gene2623	0.0	1323.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1WWTX@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
CMS1_k127_4547603_2	1123392.AQWL01000004_gene2557	5.437e-42	156.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
CMS1_k127_4547603_3	1380394.JADL01000012_gene864	6.487e-40	156.0	COG2345@1|root,COG2345@2|Bacteria,1RIDX@1224|Proteobacteria,2U9M4@28211|Alphaproteobacteria,2JSVS@204441|Rhodospirillales	204441|Rhodospirillales	K	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
CMS1_k127_4547603_1	1218084.BBJK01000017_gene1948	9.543e-64	233.0	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,2VP4G@28216|Betaproteobacteria,1K71U@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_4547603_0	1454004.AW11_02472	2.315e-176	561.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,1KQBH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	AMP-binding enzyme	bclA_2	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4591555_1	365044.Pnap_4014	6.209e-96	335.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,4A9P1@80864|Comamonadaceae	28216|Betaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
CMS1_k127_4591555_0	365044.Pnap_4013	1.686e-131	437.0	COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,2VHDS@28216|Betaproteobacteria,4A9SS@80864|Comamonadaceae	28216|Betaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA,POTRA_2,ShlB
CMS1_k127_4591555_2	87626.PTD2_03236	2.014e-06	57.0	COG4254@1|root,COG4254@2|Bacteria,1RJR0@1224|Proteobacteria,1S8WR@1236|Gammaproteobacteria,2Q1P5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_4594305_3	748247.AZKH_3413	7.209e-82	278.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS1_k127_4594305_1	76114.c2A172	2.628e-179	569.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,2KYKX@206389|Rhodocyclales	206389|Rhodocyclales	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_4594305_0	706587.Desti_4219	4.532e-183	580.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MQ5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
CMS1_k127_4594305_2	1232410.KI421419_gene2503	2.027e-112	368.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,43SFJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
CMS1_k127_4630904_0	1095769.CAHF01000009_gene1397	2.687e-158	504.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,4730X@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_4630904_1	56780.SYN_02005	2.73e-96	343.0	COG2199@1|root,COG3706@2|Bacteria,1RCC4@1224|Proteobacteria,43AED@68525|delta/epsilon subdivisions,2WQS7@28221|Deltaproteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_4630904_4	926550.CLDAP_28250	5.627e-33	133.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_4630904_3	76114.ebA1038	3.039e-66	238.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,2KWHE@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the phosphoglycerate mutase family	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS1_k127_4630904_2	580332.Slit_2212	4.027e-69	254.0	COG0457@1|root,COG0457@2|Bacteria,1P464@1224|Proteobacteria,2VMYZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF560)	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
CMS1_k127_4630904_5	653733.Selin_0214	1.158e-26	126.0	COG0810@1|root,COG4254@1|root,COG0810@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	FecR,TonB_2,TonB_C
CMS1_k127_4698954_0	1205680.CAKO01000037_gene1244	5.614e-287	890.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JQP4@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase B/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_B
CMS1_k127_4698954_2	1238182.C882_3680	9.511e-72	252.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria,2JRRQ@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_4698954_1	404589.Anae109_1731	2.579e-105	353.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7V@28221|Deltaproteobacteria,2Z1U0@29|Myxococcales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS1_k127_4703851_18	1205680.CAKO01000006_gene3416	7.268e-38	146.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,2JT6U@204441|Rhodospirillales	204441|Rhodospirillales	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
CMS1_k127_4703851_17	631454.N177_4032	1.391e-45	169.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_4703851_14	243233.MCA0498	1.012e-49	184.0	COG4094@1|root,COG4094@2|Bacteria,1RDV6@1224|Proteobacteria,1SAUX@1236|Gammaproteobacteria,1XGC9@135618|Methylococcales	135618|Methylococcales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
CMS1_k127_4703851_3	522306.CAP2UW1_3641	0.0	1098.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,1KPN6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
CMS1_k127_4703851_8	472759.Nhal_1481	1.184e-171	550.0	COG2403@1|root,COG2403@2|Bacteria,1MV4C@1224|Proteobacteria	1224|Proteobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4703851_7	522306.CAP2UW1_1014	8.794e-173	557.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KQIU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_4703851_15	1163617.SCD_n00578	5.509e-48	195.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	toluene tolerance family protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS1_k127_4703851_0	243231.GSU2758	0.0	2496.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,43TF0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_4703851_9	1288494.EBAPG3_13350	2.226e-154	501.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria,372K1@32003|Nitrosomonadales	28216|Betaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
CMS1_k127_4703851_11	267608.RSc0802	3.963e-112	381.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,1K11F@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_4703851_20	388051.AUFE01000023_gene4593	1.498e-29	128.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1KGT7@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_4703851_23	477184.KYC_21761	1.612e-06	50.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,3T5X4@506|Alcaligenaceae	28216|Betaproteobacteria	P	Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_4703851_21	1123368.AUIS01000031_gene1420	1.052e-27	115.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales	225057|Acidithiobacillales	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_4703851_16	861299.J421_4388	1.946e-46	172.0	COG3019@1|root,COG3019@2|Bacteria,1ZTWW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
CMS1_k127_4703851_12	1117647.M5M_15745	3.01e-70	244.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1J611@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_4703851_10	1049564.TevJSym_ag00830	1.094e-135	454.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1J7D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	narX	GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	2.7.13.3	ko:K07673,ko:K07674	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
CMS1_k127_4703851_13	616991.JPOO01000003_gene1698	1.431e-60	223.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	narI	GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204	1.7.5.1	ko:K00370,ko:K00374,ko:K02575	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00615,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.8,5.A.3.1	-	iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897	Nitrate_red_gam
CMS1_k127_4703851_22	616991.JPOO01000003_gene1699	2.72e-27	120.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
CMS1_k127_4703851_5	616991.JPOO01000003_gene1700	1.57e-239	758.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
CMS1_k127_4703851_1	1121920.AUAU01000008_gene1619	0.0	1608.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
CMS1_k127_4703851_19	398767.Glov_0202	6.134e-31	134.0	COG2010@1|root,COG2863@1|root,COG2010@2|Bacteria,COG2863@2|Bacteria,1MYNE@1224|Proteobacteria,437HK@68525|delta/epsilon subdivisions,2WVN9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0328	Cytochrom_C
CMS1_k127_4703851_4	1049564.TevJSym_ag00810	4.229e-294	909.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,1J96M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	nitrate nitrite transporter	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
CMS1_k127_4703851_6	653733.Selin_2438	3.143e-219	689.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
CMS1_k127_4703851_2	1000565.METUNv1_02356	0.0	1312.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2VJ2F@28216|Betaproteobacteria,2KUWZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Respiratory nitrate reductase alpha N-terminal	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
CMS1_k127_4715702_13	1472716.KBK24_0120545	3.655e-140	494.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,1K3NJ@119060|Burkholderiaceae	28216|Betaproteobacteria	U	family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
CMS1_k127_4715702_29	1458275.AZ34_13110	1.476e-74	261.0	COG0599@1|root,COG2146@1|root,COG0599@2|Bacteria,COG2146@2|Bacteria,1RCCG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Rieske
CMS1_k127_4715702_37	1123393.KB891333_gene2506	9.062e-24	110.0	2ESIQ@1|root,33K3E@2|Bacteria,1NJ20@1224|Proteobacteria,2WCCZ@28216|Betaproteobacteria,1KTFU@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4715702_36	1163617.SCD_n01889	7.17e-32	133.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,2W4P4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4715702_8	765911.Thivi_2455	4.829e-186	605.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1WXVP@135613|Chromatiales	135613|Chromatiales	P	PFAM von Willebrand factor type A	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
CMS1_k127_4715702_17	1123393.KB891317_gene2368	2.565e-117	387.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,1KRY2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,CbbQ_C
CMS1_k127_4715702_22	1469245.JFBG01000001_gene487	4.98e-95	319.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,1RQT5@1236|Gammaproteobacteria,1X0G7@135613|Chromatiales	135613|Chromatiales	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS1_k127_4715702_38	1128421.JAGA01000002_gene673	9.002e-20	95.0	COG0517@1|root,COG0517@2|Bacteria,2NRG1@2323|unclassified Bacteria	2|Bacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS1_k127_4715702_2	1469245.JFBG01000001_gene489	0.0	1081.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
CMS1_k127_4715702_27	765911.Thivi_3300	4.298e-78	263.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,1S3TG@1236|Gammaproteobacteria,1X27P@135613|Chromatiales	135613|Chromatiales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
CMS1_k127_4715702_7	396588.Tgr7_0353	8.395e-211	662.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
CMS1_k127_4715702_30	1116472.MGMO_56c00050	1.909e-65	235.0	COG4275@1|root,COG4275@2|Bacteria,1PKNM@1224|Proteobacteria,1TA92@1236|Gammaproteobacteria,1XGCM@135618|Methylococcales	135618|Methylococcales	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4715702_15	62928.azo2920	1.359e-125	418.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KUIC@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
CMS1_k127_4715702_32	375286.mma_2854	7.779e-49	190.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,47442@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS1_k127_4715702_34	1163617.SCD_n02411	8.319e-43	163.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
CMS1_k127_4715702_35	1304883.KI912532_gene3099	1.3e-33	132.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,2KX4B@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
CMS1_k127_4715702_25	290397.Adeh_2281	1.686e-81	280.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,42MIC@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	soxA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS1_k127_4715702_31	1348657.M622_12275	2.017e-56	203.0	COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,2VP4W@28216|Betaproteobacteria,2KYRD@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
CMS1_k127_4715702_5	93220.LV28_13530	1.217e-265	829.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,1K2Y9@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C
CMS1_k127_4715702_18	614083.AWQR01000055_gene1969	1.911e-114	399.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,4A9MA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
CMS1_k127_4715702_21	795666.MW7_0759	1.817e-95	319.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria,1K47S@119060|Burkholderiaceae	28216|Betaproteobacteria	V	abc transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
CMS1_k127_4715702_11	795666.MW7_0760	1.82e-148	487.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4715702_16	443144.GM21_3824	3.825e-121	413.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,43TUT@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
CMS1_k127_4715702_14	1123393.KB891333_gene2602	4.28e-130	444.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria	28216|Betaproteobacteria	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,SEC-C,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_4715702_28	204773.HEAR2618	1.794e-76	278.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VQUC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
CMS1_k127_4715702_33	930169.B5T_03471	3.396e-46	171.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XKQF@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein, major pilin PilA	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CMS1_k127_4715702_6	580332.Slit_0537	6.865e-235	739.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,44W5N@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
CMS1_k127_4715702_0	580332.Slit_0536	0.0	1129.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VNC@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GAF,T2SSE,T2SSE_N
CMS1_k127_4715702_24	580332.Slit_0535	5.005e-90	310.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,2VQGZ@28216|Betaproteobacteria	28216|Betaproteobacteria	PT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
CMS1_k127_4715702_19	580332.Slit_0534	1.085e-107	354.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,44W4T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART beta-lactamase domain protein	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS1_k127_4715702_4	640081.Dsui_1452	3.41e-283	889.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales	206389|Rhodocyclales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS1_k127_4715702_23	1000565.METUNv1_02453	7.682e-91	304.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS1_k127_4715702_20	640081.Dsui_1450	5.456e-102	340.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,2KUQG@206389|Rhodocyclales	206389|Rhodocyclales	T	Serine/threonine phosphatases, family 2C, catalytic domain	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS1_k127_4715702_1	1000565.METUNv1_02451	0.0	1090.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
CMS1_k127_4715702_12	1096546.WYO_3029	1.979e-143	460.0	COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria,2U0GD@28211|Alphaproteobacteria,1JSQ7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	PFAM formyl transferase domain protein	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_4715702_9	375286.mma_2347	3.803e-177	586.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,476TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	CoA-transferase family III	-	-	2.8.3.16,2.8.3.22	ko:K07749,ko:K14471,ko:K14472	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R00406,R03154	RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS1_k127_4715702_3	296591.Bpro_2800	1.76e-318	986.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	4.1.1.8	ko:K01577	ko00630,ko01100,map00630,map01100	-	R01908	RC00620	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_4715702_26	375286.mma_0398	1.956e-80	273.0	COG0664@1|root,COG0664@2|Bacteria,1R64V@1224|Proteobacteria,2VJXN@28216|Betaproteobacteria,472QZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_4715702_10	1121033.AUCF01000024_gene255	7.804e-167	529.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2JPTU@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
CMS1_k127_4757775_7	1348657.M622_15705	3.089e-64	224.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,2KUR3@206389|Rhodocyclales	206389|Rhodocyclales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
CMS1_k127_4757775_6	85643.Tmz1t_3656	7.166e-69	241.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS1_k127_4757775_3	305700.B447_16552	8.721e-122	397.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,2KVU7@206389|Rhodocyclales	206389|Rhodocyclales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS1_k127_4757775_0	640081.Dsui_1319	1.594e-193	612.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,2KUZY@206389|Rhodocyclales	206389|Rhodocyclales	U	type II secretion system protein	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_4757775_2	323848.Nmul_A2132	1.255e-138	452.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria,372CM@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Domain of unknown function DUF21	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_4757775_5	62928.azo3233	4.418e-69	254.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,2KW12@206389|Rhodocyclales	206389|Rhodocyclales	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_4757775_1	666681.M301_2345	3.559e-188	598.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,2KKP4@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS1_k127_4757775_4	460265.Mnod_2194	2.931e-115	379.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,1JTF7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	MA20_20705	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_4763695_0	62928.azo0815	1.217e-175	559.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_4763695_5	1121004.ATVC01000003_gene482	2.1e-31	124.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS1_k127_4763695_2	1217718.ALOU01000072_gene5026	5.653e-115	379.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,1JZYY@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_4763695_1	267608.RSc2956	4.853e-127	417.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,1JZUI@119060|Burkholderiaceae	28216|Betaproteobacteria	V	ABC transporter	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4763695_6	243160.BMA2721	1.389e-12	75.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2VXUB@28216|Betaproteobacteria,1K9F1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
CMS1_k127_4763695_4	1121035.AUCH01000003_gene1185	4.351e-57	210.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KW7C@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS1_k127_4763695_3	640081.Dsui_1401	5.334e-65	230.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,2KW45@206389|Rhodocyclales	206389|Rhodocyclales	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CMS1_k127_4834733_12	177439.DP1202	3.334e-59	211.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MHX9@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4834733_5	2340.JV46_13030	8.332e-142	459.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,1S7ID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_4834733_1	2340.JV46_13040	4.124e-170	560.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J85H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
CMS1_k127_4834733_6	2340.JV46_13050	8.227e-105	375.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1N12F@1224|Proteobacteria,1S7UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS1_k127_4834733_3	472759.Nhal_0357	5.979e-157	503.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXUS@135613|Chromatiales	1236|Gammaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_4834733_15	1500894.JQNN01000001_gene1691	2.725e-47	179.0	29DRS@1|root,300PM@2|Bacteria,1RF8B@1224|Proteobacteria,2VR3X@28216|Betaproteobacteria,4775S@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4834733_9	614083.AWQR01000040_gene755	7.538e-76	272.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria,2VK63@28216|Betaproteobacteria,4AA5X@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_4834733_13	1123392.AQWL01000011_gene2240	6.653e-53	196.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,2VKK9@28216|Betaproteobacteria,1KSYH@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
CMS1_k127_4834733_19	1123401.JHYQ01000007_gene571	1.733e-23	110.0	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,1SH3A@1236|Gammaproteobacteria,463C1@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4834733_11	76114.ebB144	6.654e-65	228.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,2KW34@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_4834733_14	1163617.SCD_n02503	3.676e-52	200.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM transport-associated	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS1_k127_4834733_7	748247.AZKH_3740	5.778e-77	263.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,2KVWJ@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS1_k127_4834733_18	522306.CAP2UW1_0585	1.977e-27	123.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,1KR1V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS1_k127_4834733_8	883126.HMPREF9710_00889	1.729e-76	265.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,472SF@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS1_k127_4834733_4	582744.Msip34_2309	6.25e-157	501.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,2KKH8@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_4834733_16	640081.Dsui_0248	1.775e-45	187.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,2KW9E@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
CMS1_k127_4834733_20	1123253.AUBD01000002_gene1232	2.959e-06	59.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X5UX@135614|Xanthomonadales	135614|Xanthomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,Response_reg
CMS1_k127_4834733_2	1038866.KB902835_gene475	8.398e-158	509.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_4834733_0	1121939.L861_22295	3.394e-195	618.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHAV@135619|Oceanospirillales	135619|Oceanospirillales	Q	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_4834733_10	1126627.BAWE01000004_gene4068	4.536e-73	252.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U4QB@28211|Alphaproteobacteria,3JRDA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_4834733_17	1380355.JNIJ01000010_gene1443	4.661e-39	149.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria,3JWB9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
CMS1_k127_4942155_3	1163617.SCD_n01884	1.292e-38	145.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored
CMS1_k127_4942155_2	1122604.JONR01000003_gene1554	6.009e-41	160.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	sagE	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_4942155_0	314278.NB231_03085	3.125e-82	280.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1WYF0@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_4942155_1	396595.TK90_0060	8.122e-67	236.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,1S2YE@1236|Gammaproteobacteria,1WY1W@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS1_k127_4942155_4	396588.Tgr7_2219	5.438e-26	111.0	2CARZ@1|root,2ZDWQ@2|Bacteria,1P7T2@1224|Proteobacteria,1STXE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4950217_22	1469245.JFBG01000032_gene1399	1.607e-41	167.0	COG0426@1|root,COG0426@2|Bacteria,1N4CQ@1224|Proteobacteria,1SC4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CMS1_k127_4950217_13	62928.azo1685	1.36e-77	267.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,2KVI8@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
CMS1_k127_4950217_4	640081.Dsui_2816	2.661e-254	803.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,2KV96@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_4950217_17	1288494.EBAPG3_3540	1.761e-56	207.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_4950217_23	1348657.M622_12655	7.382e-40	159.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS1_k127_4950217_1	640081.Dsui_2814	1.7e-322	1002.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,2KUJF@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_4950217_7	1121035.AUCH01000001_gene2039	5.396e-164	542.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,2KUQ9@206389|Rhodocyclales	206389|Rhodocyclales	FP	Exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS1_k127_4950217_0	204773.HEAR1801	0.0	1026.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,472DF@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS1_k127_4950217_14	859657.RPSI07_1666	4.952e-77	262.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,1K20G@119060|Burkholderiaceae	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS1_k127_4950217_25	62928.azo1081	3.645e-20	91.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,2KX60@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS1_k127_4950217_18	640081.Dsui_1961	3.226e-53	191.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,2KWC3@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS1_k127_4950217_6	1502852.FG94_00616	1.617e-167	532.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,472F5@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS1_k127_4950217_2	1286093.C266_11530	1.381e-299	938.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,1K1SA@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS1_k127_4950217_21	85643.Tmz1t_3019	1.844e-46	169.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,2KWPS@206389|Rhodocyclales	206389|Rhodocyclales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_4950217_20	265072.Mfla_1996	3.471e-50	181.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,2KMY6@206350|Nitrosomonadales	206350|Nitrosomonadales	K	PFAM regulatory protein MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_4950217_8	1123367.C666_15160	4.335e-111	364.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,2KU8F@206389|Rhodocyclales	206389|Rhodocyclales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS1_k127_4950217_12	1454004.AW11_03935	3.132e-78	274.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,1KQQS@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_4950217_15	640081.Dsui_1970	5.42e-65	245.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,2KU7R@206389|Rhodocyclales	206389|Rhodocyclales	DM	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
CMS1_k127_4950217_9	1112217.PPL19_06440	3.414e-87	304.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Lytic murein transglycosylase	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
CMS1_k127_4950217_5	748247.AZKH_3524	6.922e-169	555.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,2KV42@206389|Rhodocyclales	206389|Rhodocyclales	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
CMS1_k127_4950217_10	522306.CAP2UW1_1369	3.551e-80	279.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_4950217_16	522306.CAP2UW1_3009	2.524e-64	237.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_4950217_3	522306.CAP2UW1_3010	1.376e-261	818.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,1KPQK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS1_k127_4950217_11	1123392.AQWL01000001_gene1369	5.541e-80	273.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,1KSNY@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
CMS1_k127_4950217_19	1163617.SCD_n02112	1.752e-50	186.0	COG3448@1|root,COG3448@2|Bacteria,1QUQ5@1224|Proteobacteria,2WGXX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_4950217_26	1218084.BBJK01000002_gene149	3.099e-16	80.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,1K75H@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_4967935_9	946483.Cenrod_0699	8.495e-58	207.0	COG4564@1|root,COG4564@2|Bacteria,1RJP6@1224|Proteobacteria,2WEEN@28216|Betaproteobacteria,4AHTM@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	sCache_2
CMS1_k127_4967935_6	221288.JH992901_gene2456	3.92e-79	275.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria,1JIE9@1189|Stigonemataceae	1117|Cyanobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
CMS1_k127_4967935_7	883.DvMF_1949	1.291e-65	235.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,42VPN@68525|delta/epsilon subdivisions,2WRK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4967935_1	996637.SGM_6574	1.083e-253	801.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS1_k127_4967935_8	595537.Varpa_5203	1.297e-63	228.0	COG2823@1|root,COG2823@2|Bacteria,1N42J@1224|Proteobacteria,2VK5B@28216|Betaproteobacteria,4AHC6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
CMS1_k127_4967935_5	1187851.A33M_3618	2.27e-79	276.0	COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,2TUUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LPPG Fo 2-phospho-L-lactate transferase	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
CMS1_k127_4967935_0	426355.Mrad2831_5613	0.0	1116.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,1JRSQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS1_k127_4967935_12	404589.Anae109_4117	1.035e-29	118.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_4967935_10	580332.Slit_2240	3.768e-41	163.0	2DE4Z@1|root,2ZKI5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gal_Lectin
CMS1_k127_4967935_11	757424.Hsero_4045	3.047e-39	159.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,474BT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
CMS1_k127_4967935_3	543728.Vapar_1203	3.374e-101	334.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,4AAHE@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS1_k127_4967935_4	1031711.RSPO_c00574	6.683e-84	287.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,1K1CF@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Cytochrome C1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
CMS1_k127_4967935_2	582744.Msip34_0283	1.103e-103	340.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,2KKSW@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS1_k127_4990506_3	589865.DaAHT2_2409	1.075e-78	271.0	COG1216@1|root,COG1216@2|Bacteria,1R13V@1224|Proteobacteria,43D64@68525|delta/epsilon subdivisions,2X8CV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_4990506_5	589865.DaAHT2_1612	3.172e-35	148.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,42P9A@68525|delta/epsilon subdivisions,2WIW1@28221|Deltaproteobacteria,2MKQR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_4990506_4	398527.Bphyt_3918	9.332e-73	256.0	COG0583@1|root,COG0583@2|Bacteria,1MV0E@1224|Proteobacteria,2VM44@28216|Betaproteobacteria,1K2UV@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transcriptional Regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4990506_1	1411123.JQNH01000001_gene1859	8.811e-116	380.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TSPM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	MA20_43195	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_4990506_0	1218084.BBJK01000044_gene3870	2.143e-129	440.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_14,TPR_16,TPR_2,TPR_4,TPR_8
CMS1_k127_4990506_7	441620.Mpop_2362	6.911e-28	132.0	COG0572@1|root,COG0572@2|Bacteria,1N9DY@1224|Proteobacteria,2UMU9@28211|Alphaproteobacteria,1JS9F@119045|Methylobacteriaceae	28211|Alphaproteobacteria	F	AAA domain	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_4990506_2	96561.Dole_0615	5.563e-98	327.0	28MMY@1|root,2ZAXJ@2|Bacteria,1R773@1224|Proteobacteria,42ZX9@68525|delta/epsilon subdivisions,2WVE6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4990506_6	96561.Dole_0613	1.144e-33	141.0	2EN50@1|root,33FT1@2|Bacteria,1NIJS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4990992_0	420662.Mpe_A1708	0.0	1737.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2VJ2F@28216|Betaproteobacteria,1KJ07@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	-	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
CMS1_k127_4990992_1	1000565.METUNv1_02355	8.25e-296	911.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VJ1V@28216|Betaproteobacteria,2KVF3@206389|Rhodocyclales	206389|Rhodocyclales	C	Respiratory nitrate reductase beta C-terminal	narH	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
CMS1_k127_4990992_13	1122962.AULH01000012_gene683	8.727e-49	199.0	COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,2U19T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Nitrate reductase, delta subunit	narJ	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
CMS1_k127_4990992_7	1000565.METUNv1_02353	7.179e-88	295.0	COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,2VK31@28216|Betaproteobacteria,2KVY7@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrate reductase gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
CMS1_k127_4990992_15	580332.Slit_1694	8.986e-33	143.0	COG1416@1|root,COG1416@2|Bacteria,1RE8C@1224|Proteobacteria,2VV8B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
CMS1_k127_4990992_11	1163617.SCD_n01931	2.464e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,1RKQH@1224|Proteobacteria,2VSYG@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4990992_14	1123393.KB891316_gene1119	1.924e-35	146.0	COG1416@1|root,COG5662@1|root,COG1416@2|Bacteria,COG5662@2|Bacteria,1MYMK@1224|Proteobacteria,2VTJT@28216|Betaproteobacteria,1KSAM@119069|Hydrogenophilales	119069|Hydrogenophilales	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4990992_5	1095769.CAHF01000026_gene1646	1.006e-125	423.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,472VU@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
CMS1_k127_4990992_9	1395571.TMS3_0114975	2.78e-70	245.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
CMS1_k127_4990992_4	365046.Rta_26240	1.212e-138	456.0	COG2270@1|root,COG2270@2|Bacteria,1QWEU@1224|Proteobacteria	1224|Proteobacteria	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4990992_3	518766.Rmar_2208	8.433e-205	651.0	COG1960@1|root,COG1960@2|Bacteria,4NEM4@976|Bacteroidetes,1FJQH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
CMS1_k127_4990992_10	29581.BW37_04914	1.524e-57	212.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,4745S@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	cheW8	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS1_k127_4990992_6	261292.Nit79A3_2712	6.246e-104	359.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,371T6@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	ko:K03406,ko:K03776,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH
CMS1_k127_4990992_12	316067.Geob_0726	1.433e-50	190.0	COG2067@1|root,COG2067@2|Bacteria,1N1F4@1224|Proteobacteria,42ZP2@68525|delta/epsilon subdivisions,2WUUM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS1_k127_4990992_2	472759.Nhal_1456	2.835e-281	872.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_4990992_8	2340.JV46_14190	4.128e-74	267.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_5100946_4	596154.Alide2_2167	2.079e-137	445.0	COG0697@1|root,COG4531@1|root,COG0697@2|Bacteria,COG4531@2|Bacteria,1N3FA@1224|Proteobacteria,2VHAD@28216|Betaproteobacteria,4ABD4@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Drug metabolite transporter	cnrT	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_5100946_1	1207063.P24_01465	2.05e-290	917.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2TSXZ@28211|Alphaproteobacteria,2JPCU@204441|Rhodospirillales	204441|Rhodospirillales	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
CMS1_k127_5100946_16	748247.AZKH_1814	3.296e-32	127.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,2KX94@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_5100946_2	323848.Nmul_A0510	5.071e-152	494.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VZIT@28216|Betaproteobacteria,371QJ@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_5100946_0	640081.Dsui_0500	1.164e-293	917.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,2KVJT@206389|Rhodocyclales	206389|Rhodocyclales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_5100946_17	1454004.AW11_01454	9.174e-25	104.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,1KQ5S@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS1_k127_5100946_14	1123367.C666_08865	9.35e-68	236.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,2KVFX@206389|Rhodocyclales	206389|Rhodocyclales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS1_k127_5100946_11	85643.Tmz1t_4021	1.04e-85	293.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,2KUSK@206389|Rhodocyclales	206389|Rhodocyclales	S	Stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS1_k127_5100946_6	159087.Daro_3849	1.192e-127	415.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,2KUA5@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_5100946_12	62928.azo3962	6.248e-75	261.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,2KUHY@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS1_k127_5100946_8	1211114.ALIP01000098_gene1855	1.067e-102	353.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1X3QU@135614|Xanthomonadales	135614|Xanthomonadales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS1_k127_5100946_13	267608.RSc2160	2.288e-74	256.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,1K2WW@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS1_k127_5100946_3	748247.AZKH_4451	2.095e-146	477.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,2KUR1@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_5100946_9	1123354.AUDR01000011_gene1482	1.68e-91	319.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1KRJ6@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Putative methyltransferase	-	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS1_k127_5100946_5	1123487.KB892834_gene2676	3.031e-133	432.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,2KURE@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS1_k127_5100946_18	292415.Tbd_2127	7.998e-21	93.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,1KTG0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_5100946_10	1000565.METUNv1_01912	3.01e-88	307.0	COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,2VTTP@28216|Betaproteobacteria,2KYW8@206389|Rhodocyclales	206389|Rhodocyclales	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS1_k127_5100946_7	1265502.KB905933_gene1994	2.821e-126	414.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,2VJKN@28216|Betaproteobacteria,4AAV8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 5-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
CMS1_k127_5100946_15	1485544.JQKP01000003_gene284	1.02e-51	205.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CMS1_k127_5130608_1	1500894.JQNN01000001_gene399	7.258e-192	628.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,475DR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE2,PAS_4,PAS_9
CMS1_k127_5130608_9	243365.CV_2354	1.451e-67	239.0	COG0596@1|root,COG0596@2|Bacteria,1QUVT@1224|Proteobacteria,2WGRR@28216|Betaproteobacteria,2KR10@206351|Neisseriales	206351|Neisseriales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_5130608_12	522306.CAP2UW1_1845	4.387e-26	114.0	COG5010@1|root,COG5010@2|Bacteria,1R0QI@1224|Proteobacteria,2VX62@28216|Betaproteobacteria,1KR08@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5130608_13	472759.Nhal_2805	1.815e-22	100.0	2D7FD@1|root,32TNY@2|Bacteria,1NAHU@1224|Proteobacteria,1S9DD@1236|Gammaproteobacteria,1WYZ8@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
CMS1_k127_5130608_3	744985.HIMB59_00011800	4.62e-117	403.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TSME@28211|Alphaproteobacteria,4BTAG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	MA20_16750	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_5130608_2	398578.Daci_2550	4.381e-173	548.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2VI04@28216|Betaproteobacteria,4AASZ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
CMS1_k127_5130608_14	1136138.JH604624_gene4227	1.337e-15	81.0	2EGJ5@1|root,33ABC@2|Bacteria,1NI51@1224|Proteobacteria,1SH35@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1161)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1161
CMS1_k127_5130608_7	671143.DAMO_0872	3.115e-83	289.0	COG2267@1|root,COG2267@2|Bacteria,2NRR1@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_5130608_5	292415.Tbd_1468	2.387e-95	334.0	COG1524@1|root,COG1524@2|Bacteria,1R2II@1224|Proteobacteria,2VMR9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_5130608_15	272560.BPSL0387	3.979e-09	69.0	2E6W9@1|root,331FT@2|Bacteria,1N6E1@1224|Proteobacteria,2VVIR@28216|Betaproteobacteria,1K8KB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3567)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3567
CMS1_k127_5130608_10	1163617.SCD_n02073	2.529e-45	170.0	2CCFR@1|root,2Z7VF@2|Bacteria,1MXHU@1224|Proteobacteria,2VHMR@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5130608_0	640081.Dsui_3018	7.254e-219	685.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,2KVQ4@206389|Rhodocyclales	206389|Rhodocyclales	H	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_5130608_8	288000.BBta_3175	9.688e-73	271.0	COG2267@1|root,COG2267@2|Bacteria,1Q6AF@1224|Proteobacteria,2U163@28211|Alphaproteobacteria,3JSQF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	MA20_21410	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
CMS1_k127_5130608_4	595537.Varpa_4268	4.981e-110	372.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2VIUQ@28216|Betaproteobacteria,4A9JA@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM multi antimicrobial extrusion protein MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_5130608_11	351348.Maqu_3065	5.321e-35	136.0	COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,1SDBW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	effector of murein hydrolase LrgA	-	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
CMS1_k127_5130608_6	264198.Reut_A2795	2.243e-85	294.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2VH4N@28216|Betaproteobacteria,1K2SA@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM LrgB family protein	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
CMS1_k127_5202323_4	1218076.BAYB01000012_gene2643	5.102e-35	138.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1K73W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
CMS1_k127_5202323_1	123899.JPQP01000019_gene2501	2.868e-89	312.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2VKKP@28216|Betaproteobacteria,3T2PC@506|Alcaligenaceae	28216|Betaproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
CMS1_k127_5202323_2	1449063.JMLS01000041_gene4908	7.046e-71	261.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,26SC6@186822|Paenibacillaceae	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
CMS1_k127_5202323_3	1123073.KB899243_gene490	1.123e-54	200.0	COG1984@1|root,COG2049@1|root,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,1X6MH@135614|Xanthomonadales	135614|Xanthomonadales	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
CMS1_k127_5202323_5	981223.AIED01000028_gene365	0.0002564	48.0	2AZUS@1|root,31S44@2|Bacteria,1QPM2@1224|Proteobacteria,1TNBK@1236|Gammaproteobacteria,3NQAU@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5202323_0	472759.Nhal_0463	5.916e-90	305.0	COG3408@1|root,COG3408@2|Bacteria,1PGVT@1224|Proteobacteria,1SHCY@1236|Gammaproteobacteria,1WZTG@135613|Chromatiales	135613|Chromatiales	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100
CMS1_k127_5285589_0	65393.PCC7424_3782	0.0	1322.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria,3KGJ5@43988|Cyanothece	1117|Cyanobacteria	H	PFAM D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
CMS1_k127_5285589_2	306281.AJLK01000118_gene4092	0.0	1149.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
CMS1_k127_5285589_51	472759.Nhal_2002	9.633e-21	98.0	COG1403@1|root,COG1403@2|Bacteria,1QTCI@1224|Proteobacteria,1SV2C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5285589_50	266264.Rmet_5384	9.582e-22	95.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,2VW5A@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS1_k127_5285589_46	937777.Deipe_2227	2.087e-32	132.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	1.1.1.42,1.3.1.85	ko:K00031,ko:K14446	ko00020,ko00480,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00373,M00740	R00267,R00268,R01899,R09291	RC00001,RC00084,RC00114,RC00626,RC02481,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,GGDEF,PAS_9
CMS1_k127_5285589_41	1121035.AUCH01000002_gene1607	1.174e-50	202.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,2VKDF@28216|Betaproteobacteria,2KW64@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
CMS1_k127_5285589_7	1304883.KI912532_gene399	2.015e-229	726.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,2KVHZ@206389|Rhodocyclales	206389|Rhodocyclales	C	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4_10,POR_N,TPP_enzyme_C
CMS1_k127_5285589_39	243365.CV_0968	2.377e-57	204.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2WFK8@28216|Betaproteobacteria,2KQZY@206351|Neisseriales	206351|Neisseriales	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_5285589_22	595537.Varpa_1641	2.581e-136	450.0	COG0240@1|root,COG0240@2|Bacteria,1MXI9@1224|Proteobacteria,2VW0B@28216|Betaproteobacteria,4AJYR@80864|Comamonadaceae	28216|Betaproteobacteria	C	NAD NADP octopine nopaline dehydrogenase	-	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	ApbA,NAD_Gly3P_dh_N,Octopine_DH
CMS1_k127_5285589_26	391937.NA2_14487	3.535e-110	383.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,43MMU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS1_k127_5285589_12	1231391.AMZF01000022_gene1261	1.287e-187	591.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,3T2I2@506|Alcaligenaceae	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5285589_34	1380394.JADL01000003_gene4940	5.861e-85	288.0	COG4221@1|root,COG4221@2|Bacteria,1QW75@1224|Proteobacteria,2TWQR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	KR domain	MA20_16520	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5285589_52	479434.Sthe_2009	2.066e-15	85.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi,27YM9@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS1_k127_5285589_9	1125863.JAFN01000001_gene1222	1.64e-216	718.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_5285589_8	1125863.JAFN01000001_gene1223	4.556e-218	719.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_5285589_23	1231391.AMZF01000022_gene1262	9.796e-131	429.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2W9BE@28216|Betaproteobacteria,3T5JA@506|Alcaligenaceae	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_5285589_25	94624.Bpet1715	4.384e-118	391.0	COG0559@1|root,COG0559@2|Bacteria,1MXMC@1224|Proteobacteria,2VJ1Y@28216|Betaproteobacteria,3T1VK@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_5285589_10	159087.Daro_4098	9.108e-216	703.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,2KUY7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
CMS1_k127_5285589_33	402626.Rpic_4524	1.503e-87	319.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNG@28216|Betaproteobacteria,1K20Y@119060|Burkholderiaceae	28216|Betaproteobacteria	E	abc transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_5285589_35	1411123.JQNH01000001_gene3240	1.332e-83	301.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TTP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	bcpA	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
CMS1_k127_5285589_17	762376.AXYL_02583	4.226e-166	544.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2W8GX@28216|Betaproteobacteria,3T709@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5285589_49	1320556.AVBP01000016_gene2752	8.866e-25	120.0	COG1719@1|root,COG1719@2|Bacteria,1PZY6@1224|Proteobacteria,2UV2G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	V4R	-	-	-	-	-	-	-	-	-	-	-	-	V4R
CMS1_k127_5285589_31	76114.ebA2079	9.855e-95	323.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,2KU72@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in response to NO	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
CMS1_k127_5285589_14	76114.ebA2066	1.673e-178	572.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_5285589_1	76114.ebA2064	0.0	1268.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,2KYPD@206389|Rhodocyclales	206389|Rhodocyclales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5285589_42	1449126.JQKL01000016_gene2868	1.786e-46	172.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,26967@186813|unclassified Clostridiales	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_5285589_30	76114.ebA2062	1.7e-100	334.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2WGS8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_5285589_5	76114.ebA2060	4.659e-273	849.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,2KV3E@206389|Rhodocyclales	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase	icmF	-	5.4.99.2,5.4.99.63,5.4.99.64	ko:K01847,ko:K01848,ko:K14447,ko:K20906	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS1_k127_5285589_40	76114.ebD52	4.438e-56	215.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,2VW7W@28216|Betaproteobacteria	28216|Betaproteobacteria	I	B12 binding domain	-	-	5.4.99.2,5.4.99.64	ko:K01849,ko:K20907	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CMS1_k127_5285589_13	76114.ebA2055	8.083e-187	599.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,2KVJQ@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5285589_36	1232437.KL662057_gene3891	8.721e-64	237.0	COG0346@1|root,COG0346@2|Bacteria,1RGGX@1224|Proteobacteria,42RWH@68525|delta/epsilon subdivisions,2WNU6@28221|Deltaproteobacteria,2MNHP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS1_k127_5285589_18	1244869.H261_12236	7.935e-152	512.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JPCT@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5285589_11	316055.RPE_3219	2.578e-196	632.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,2TUBT@28211|Alphaproteobacteria,3K2FJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_5285589_37	316055.RPE_3220	6.689e-60	235.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2TUKM@28211|Alphaproteobacteria,3JUR2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	GntR family	MA20_10290	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_5285589_3	76114.ebA2038	2.835e-287	896.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VGZU@28216|Betaproteobacteria,2KY7I@206389|Rhodocyclales	1224|Proteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_5285589_4	706587.Desti_1834	1.031e-283	893.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2MQZU@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_5285589_6	706587.Desti_1835	1.72e-231	729.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MS4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_5285589_32	1122604.JONR01000009_gene2440	1.48e-88	303.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RZ74@1236|Gammaproteobacteria,1X6N8@135614|Xanthomonadales	135614|Xanthomonadales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5285589_20	1318628.MARLIPOL_09831	1.656e-146	485.0	COG0491@1|root,COG0494@1|root,COG0491@2|Bacteria,COG0494@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria,46AP6@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	blaB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,NUDIX
CMS1_k127_5285589_16	570952.ATVH01000011_gene325	4.634e-167	542.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2JPC2@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_5285589_19	1123368.AUIS01000004_gene125	2.346e-151	488.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,2NCIC@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_5285589_43	1532557.JL37_10335	1.81e-33	138.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria,3T7T0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_5285589_29	1095769.CAHF01000001_gene3532	5.332e-103	338.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,473B4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	bbsI	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS1_k127_5285589_38	1288494.EBAPG3_7620	6.862e-60	231.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,372CE@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS1_k127_5285589_28	1040989.AWZU01000003_gene6816	1.296e-105	355.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TWR2@28211|Alphaproteobacteria,3JVDD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5285589_24	296591.Bpro_4819	5.33e-125	432.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2VIUU@28216|Betaproteobacteria,4ACPR@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM alanine racemase domain protein	-	-	4.1.2.42	ko:K19967	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS1_k127_5285589_27	1123367.C666_14215	7.645e-109	366.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2VKPZ@28216|Betaproteobacteria,2KW84@206389|Rhodocyclales	206389|Rhodocyclales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_5285589_21	1485544.JQKP01000001_gene1283	2.044e-136	445.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,44WA4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_5285589_48	1163617.SCD_n00026	5.592e-26	122.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS1_k127_5285589_44	637390.AFOH01000013_gene707	6.594e-33	131.0	COG2210@1|root,COG2210@2|Bacteria,1NXM5@1224|Proteobacteria,1SREE@1236|Gammaproteobacteria,2NCZR@225057|Acidithiobacillales	225057|Acidithiobacillales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS1_k127_5285589_47	547144.HydHO_0590	9.582e-27	111.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
CMS1_k127_5285589_15	637390.AFOH01000013_gene705	6.544e-178	563.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria,2NCAJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_5285589_45	637389.Acaty_c2264	9.313e-33	134.0	290SD@1|root,2ZNEH@2|Bacteria,1P6XW@1224|Proteobacteria,1STK8@1236|Gammaproteobacteria,2NC0Z@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5360761_3	985054.JQEZ01000004_gene966	9.835e-36	140.0	COG1917@1|root,COG1917@2|Bacteria,1MZD8@1224|Proteobacteria,2UBX5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_5360761_2	1532557.JL37_18315	1.022e-59	210.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2VUC4@28216|Betaproteobacteria,3T7DE@506|Alcaligenaceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme family protein 4	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_5360761_4	99598.Cal7507_0558	7.753e-34	138.0	COG0625@1|root,COG0625@2|Bacteria	2|Bacteria	O	glutathione transferase activity	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
CMS1_k127_5360761_0	1002672.SAR11G3_01300	8.893e-168	534.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2UBG9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5360761_1	1173020.Cha6605_0969	1.624e-61	219.0	COG0702@1|root,COG0702@2|Bacteria,1G3PB@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_5429663_26	1192124.LIG30_4774	3.381e-39	150.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VM20@28216|Betaproteobacteria,1K1DQ@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM ABC transporter related	hndI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_5429663_14	740709.A10D4_13143	2.088e-139	463.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,2QFKS@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	POTRA domain TamA domain 1	tamA	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
CMS1_k127_5429663_5	1049564.TevJSym_an00700	9.103e-214	709.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1J546@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ytfN	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS1_k127_5429663_7	640081.Dsui_0605	3.719e-200	629.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KU9J@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_5429663_9	1304883.KI912532_gene1127	9.899e-196	613.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_5429663_19	272560.BPSL2846	2.608e-85	288.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1JZTS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS1_k127_5429663_20	1123487.KB892856_gene2548	1.294e-83	291.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,2KUUS@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS1_k127_5429663_23	748247.AZKH_3846	6.038e-47	175.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,2KWT0@206389|Rhodocyclales	206389|Rhodocyclales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CMS1_k127_5429663_32	580332.Slit_2755	4.832e-15	86.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,44VYI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS1_k127_5429663_4	1500894.JQNN01000001_gene3519	5.557e-218	695.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,4739B@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
CMS1_k127_5429663_1	388051.AUFE01000040_gene3285	4.468e-226	708.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,1K38Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
CMS1_k127_5429663_13	640081.Dsui_0892	1.983e-145	473.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,2KURV@206389|Rhodocyclales	206389|Rhodocyclales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS1_k127_5429663_0	1304883.KI912532_gene700	2.005e-256	805.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,2KUYH@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_5429663_25	305700.B447_06005	3.771e-43	167.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,2KW9X@206389|Rhodocyclales	206389|Rhodocyclales	M	shape-determining protein	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
CMS1_k127_5429663_21	640081.Dsui_0889	4.011e-81	280.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,2KUC9@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_5429663_8	640081.Dsui_0888	8.44e-198	619.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,2KUHG@206389|Rhodocyclales	206389|Rhodocyclales	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_5429663_30	62928.azo0173	1.1e-27	115.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,2KWWQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CMS1_k127_5429663_3	1163617.SCD_n00095	2.634e-221	702.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_5429663_6	1123392.AQWL01000002_gene2019	4.794e-203	666.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,1KRG5@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_5429663_31	640081.Dsui_0874	2.568e-19	95.0	2B8F5@1|root,321Q6@2|Bacteria,1RKTZ@1224|Proteobacteria,2WHV8@28216|Betaproteobacteria,2KXCY@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5429663_17	1286093.C266_15819	9.398e-94	342.0	COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2VSR8@28216|Betaproteobacteria,1K1C7@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS1_k127_5429663_16	1218076.BAYB01000021_gene3753	4.539e-111	377.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,1K01S@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Exodeoxyribonuclease III	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_5429663_12	388051.AUFE01000019_gene4397	2.093e-147	486.0	COG2223@1|root,COG2223@2|Bacteria,1QU4X@1224|Proteobacteria,2WH87@28216|Betaproteobacteria,1KIIC@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Acetyl-coenzyme A transporter 1	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
CMS1_k127_5429663_28	1255043.TVNIR_2995	1.616e-33	143.0	2DBUS@1|root,2ZB7H@2|Bacteria,1R4EC@1224|Proteobacteria,1T19I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5429663_22	580332.Slit_0035	1.494e-78	271.0	COG2890@1|root,COG2890@2|Bacteria,1R0WI@1224|Proteobacteria	1224|Proteobacteria	J	TIGRFAM methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
CMS1_k127_5429663_10	62928.azo3971	9.861e-184	581.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,2KVER@206389|Rhodocyclales	206389|Rhodocyclales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_5429663_11	257310.BB4886	2.287e-161	517.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2VKB0@28216|Betaproteobacteria,3T2RR@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_5429663_2	1288494.EBAPG3_5570	2.617e-221	700.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,371S3@32003|Nitrosomonadales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS1_k127_5429663_29	62928.azo3781	2.619e-33	130.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,2KWVF@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphotransferase System	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS1_k127_5429663_24	1236959.BAMT01000006_gene336	8.486e-45	166.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,2KMX4@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
CMS1_k127_5429663_15	243160.BMA3214	1.512e-122	403.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,1K2PI@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CMS1_k127_5429663_27	1288494.EBAPG3_5400	2.097e-37	147.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,3739S@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_5429663_33	1150469.RSPPHO_02781	9.548e-05	53.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5429663_18	1121861.KB899953_gene2388	3.201e-86	293.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,2JRIJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_5438022_17	76114.c2A173	4.368e-114	376.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria,2KXZX@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS1_k127_5438022_28	1000565.METUNv1_00458	6.132e-43	161.0	COG0589@1|root,COG0589@2|Bacteria,1NDDA@1224|Proteobacteria,2VUKE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_5438022_3	1207063.P24_13268	1.963e-217	699.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JUZH@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5438022_23	870187.Thini_3918	1.358e-67	241.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,461BK@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5438022_26	298655.KI912266_gene2271	2.896e-47	186.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CMS1_k127_5438022_21	1144342.PMI40_01944	1.612e-70	246.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,473BT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	haloacid dehalogenase-like hydrolase	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_5438022_19	1454004.AW11_01410	1.518e-107	355.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,1KPWN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
CMS1_k127_5438022_25	1265502.KB905934_gene3179	2.762e-53	195.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4ACAI@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	ompA	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
CMS1_k127_5438022_5	1000565.METUNv1_02721	2.489e-176	563.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KV5W@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS1_k127_5438022_29	748247.AZKH_3561	7.401e-27	117.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,2KYX2@206389|Rhodocyclales	206389|Rhodocyclales	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
CMS1_k127_5438022_0	1123487.KB892838_gene3825	0.0	1292.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,2KV41@206389|Rhodocyclales	206389|Rhodocyclales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_5438022_9	1123368.AUIS01000020_gene1092	7.237e-165	526.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,2NCS3@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_5438022_10	395495.Lcho_3015	1.985e-164	526.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,1KMB7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_5438022_15	305700.B447_01101	2.528e-131	427.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,2KUSW@206389|Rhodocyclales	206389|Rhodocyclales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS1_k127_5438022_14	1163617.SCD_n01029	5.126e-142	460.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5438022_20	1500894.JQNN01000001_gene268	1.077e-95	322.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,472S1@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_5438022_6	859657.RPSI07_2477	2.236e-174	571.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,1K0P7@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
CMS1_k127_5438022_24	1123393.KB891317_gene2455	2.589e-67	237.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2VQ2F@28216|Betaproteobacteria,1KRY6@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Cytidylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin
CMS1_k127_5438022_1	323848.Nmul_A2069	2.051e-294	912.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,372RZ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS1_k127_5438022_27	1123367.C666_02715	4.001e-46	168.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,2KWNF@206389|Rhodocyclales	206389|Rhodocyclales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_5438022_30	640081.Dsui_1945	8.188e-15	78.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,2KXEI@206389|Rhodocyclales	206389|Rhodocyclales	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
CMS1_k127_5438022_8	640081.Dsui_1946	1.576e-167	534.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,2KU7Z@206389|Rhodocyclales	206389|Rhodocyclales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
CMS1_k127_5438022_4	1454004.AW11_03748	5.86e-196	636.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,1KQF4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_5438022_16	640081.Dsui_1952	1.355e-115	400.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,2KV89@206389|Rhodocyclales	206389|Rhodocyclales	M	pfkB family carbohydrate kinase	-	-	2.7.1.167	ko:K21344	ko00540,map00540	M00064	R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS1_k127_5438022_13	1123393.KB891317_gene2463	1.33e-147	475.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,1KRKH@119069|Hydrogenophilales	119069|Hydrogenophilales	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
CMS1_k127_5438022_12	159087.Daro_1287	1.484e-151	500.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,2KV1N@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_5438022_18	580332.Slit_2299	4.859e-108	361.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,44V01@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CMS1_k127_5438022_11	1304883.KI912532_gene1767	3.493e-163	540.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,2KVES@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS1_k127_5438022_22	580332.Slit_2295	2.94e-69	243.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,44VNR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
CMS1_k127_5438022_31	1168059.KB899087_gene1061	1.34e-06	55.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_5438022_7	314271.RB2654_18051	3.868e-169	537.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	4.1.1.103,4.1.1.46	ko:K07045,ko:K14333,ko:K20941	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821,R11353	RC00390,RC00569	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS1_k127_5438022_2	314271.RB2654_18046	5.92e-234	737.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_5451138_9	420662.Mpe_A0904	2.241e-32	128.0	COG0614@1|root,COG0614@2|Bacteria,1PKNF@1224|Proteobacteria,2VMK5@28216|Betaproteobacteria,1KJ2A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_5451138_7	580332.Slit_1776	2.893e-67	246.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	Bac_surface_Ag
CMS1_k127_5451138_2	266264.Rmet_5019	1.343e-158	509.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJJQ@28216|Betaproteobacteria,1K237@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS1_k127_5451138_6	640081.Dsui_3024	8.014e-70	270.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,2VKF1@28216|Betaproteobacteria,2KW8U@206389|Rhodocyclales	206389|Rhodocyclales	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CMS1_k127_5451138_1	640081.Dsui_3023	5.075e-164	521.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,2KVRY@206389|Rhodocyclales	206389|Rhodocyclales	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS1_k127_5451138_8	543913.D521_0543	1.419e-33	139.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,1KR0V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
CMS1_k127_5451138_0	388051.AUFE01000005_gene1068	2.985e-220	696.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIA6@28216|Betaproteobacteria,1K2QB@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Activates fatty acids by binding to coenzyme A	fadD2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5451138_3	319003.Bra1253DRAFT_04105	1.65e-140	455.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,3JW29@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	MA20_06335	-	4.2.1.156,4.2.1.42,5.1.2.2	ko:K01781,ko:K20023	ko00053,ko00627,ko01120,map00053,map00627,map01120	-	R03791,R04161,R05608	RC00543,RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5451138_4	331869.BAL199_27166	8.519e-120	391.0	COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_5451138_5	1429916.X566_18070	5.231e-88	297.0	COG4221@1|root,COG4221@2|Bacteria,1QW75@1224|Proteobacteria,2TWQR@28211|Alphaproteobacteria,3JTEM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	KR domain	MA20_16520	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5451138_10	267608.RSc1203	1.147e-27	114.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,1K27J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5475849_42	1095769.CAHF01000010_gene1222	1.249e-76	262.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,47249@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_5475849_35	62928.azo2114	1.192e-87	294.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,2KUMD@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the SUA5 family	yrdC	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
CMS1_k127_5475849_43	1163617.SCD_n01477	2.989e-76	260.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS1_k127_5475849_12	1163617.SCD_n01478	9.487e-209	665.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS1_k127_5475849_33	757424.Hsero_3092	2.502e-96	327.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,473K8@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS1_k127_5475849_40	267608.RSc1285	5.703e-78	265.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,1K1RS@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS1_k127_5475849_41	1216976.AX27061_1681	1.746e-77	271.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,3T1QT@506|Alcaligenaceae	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_5475849_64	1266925.JHVX01000009_gene74	1.045e-43	164.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,37338@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS1_k127_5475849_11	1266925.JHVX01000009_gene73	1.999e-224	705.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,372CV@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS1_k127_5475849_1	395019.Bmul_1755	0.0	1045.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,1K43X@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
CMS1_k127_5475849_66	1163617.SCD_n01714	2.832e-36	140.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS1_k127_5475849_37	1123368.AUIS01000006_gene688	8.461e-84	290.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,2NCPG@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
CMS1_k127_5475849_68	887898.HMPREF0551_1176	4.528e-33	134.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,1K8J9@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS1_k127_5475849_2	640081.Dsui_2718	0.0	1039.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,2KUVE@206389|Rhodocyclales	206389|Rhodocyclales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS1_k127_5475849_49	1163617.SCD_n01709	7.823e-65	233.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VRPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS1_k127_5475849_75	1415778.JQMM01000001_gene2084	1.561e-11	69.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5475849_36	335283.Neut_0593	5.955e-85	292.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,371MJ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
CMS1_k127_5475849_14	1007105.PT7_0724	1.51e-166	531.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,3T1MH@506|Alcaligenaceae	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_5475849_17	159087.Daro_1725	1.312e-140	458.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,2KVCM@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_5475849_20	1000565.METUNv1_01317	8.72e-132	424.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,2KUZC@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CMS1_k127_5475849_13	640081.Dsui_2708	8.928e-173	554.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,2KVDP@206389|Rhodocyclales	206389|Rhodocyclales	E	PFAM Aminotransferase class I and II	dapC	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5475849_52	1288494.EBAPG3_960	1.774e-61	215.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2WAWH@28216|Betaproteobacteria,3734U@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS1_k127_5475849_3	640081.Dsui_2703	7.898e-317	1016.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,2KV3S@206389|Rhodocyclales	206389|Rhodocyclales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS1_k127_5475849_69	1454004.AW11_03722	4.699e-33	142.0	COG3115@1|root,COG3115@2|Bacteria,1N66I@1224|Proteobacteria,2VUCK@28216|Betaproteobacteria,1KQ57@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	-	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
CMS1_k127_5475849_7	1218074.BAXZ01000003_gene701	8.406e-270	845.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1K0GW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS1_k127_5475849_24	159087.Daro_1735	7.187e-120	397.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,2KUS0@206389|Rhodocyclales	206389|Rhodocyclales	M	UTP-glucose-1-phosphate uridylyltransferase	epsT	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_5475849_53	1255043.TVNIR_1605	3.238e-61	221.0	COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,1SE6E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,DrsE_2
CMS1_k127_5475849_56	748280.NH8B_0478	2.182e-59	210.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,2KQWS@206351|Neisseriales	206351|Neisseriales	F	Psort location Cytoplasmic, score 9.97	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS1_k127_5475849_29	1000565.METUNv1_01305	2.818e-107	355.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,2KV4J@206389|Rhodocyclales	206389|Rhodocyclales	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_5475849_44	522306.CAP2UW1_3626	2.253e-75	263.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,1KQKV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_5475849_4	1000565.METUNv1_01302	2.703e-316	1005.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,2KV4M@206389|Rhodocyclales	206389|Rhodocyclales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
CMS1_k127_5475849_19	1304883.KI912532_gene2610	3.204e-137	443.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,2KUH5@206389|Rhodocyclales	206389|Rhodocyclales	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_5475849_23	323848.Nmul_A0657	1.812e-121	393.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,371SG@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS1_k127_5475849_32	1288494.EBAPG3_810	8.411e-105	352.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,3722G@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS1_k127_5475849_25	640081.Dsui_2692	5.064e-118	388.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,2KVY1@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_5475849_39	1000565.METUNv1_01297	3.917e-79	270.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,2KV5P@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS1_k127_5475849_27	640081.Dsui_2690	7.832e-112	366.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,2KV64@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_5475849_62	292415.Tbd_0790	6.004e-49	190.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,1KRPS@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS1_k127_5475849_15	62928.azo1903	2.381e-144	470.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,2KVYE@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS1_k127_5475849_16	522306.CAP2UW1_2869	5.638e-143	482.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1KQ8B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS1_k127_5475849_5	1163617.SCD_n01627	4.13e-297	929.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS1_k127_5475849_59	85643.Tmz1t_2169	3.363e-51	194.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,2KWH8@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the skp family	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS1_k127_5475849_26	395494.Galf_1783	7.188e-114	377.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,44V3V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS1_k127_5475849_57	1165096.ARWF01000001_gene357	2.057e-56	203.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,2KMMW@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_5475849_30	305700.B447_05288	4.479e-107	360.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KV6X@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS1_k127_5475849_18	640081.Dsui_2681	2.737e-137	460.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,2KUHP@206389|Rhodocyclales	206389|Rhodocyclales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS1_k127_5475849_47	1485544.JQKP01000007_gene1945	1.402e-68	240.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,44VRD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_5475849_51	1121035.AUCH01000017_gene2315	1.004e-61	221.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,2KW4N@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_5475849_31	1121035.AUCH01000017_gene2317	1.304e-105	352.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,2KVFV@206389|Rhodocyclales	206389|Rhodocyclales	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
CMS1_k127_5475849_0	1123354.AUDR01000014_gene1000	0.0	1125.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHQ3@28216|Betaproteobacteria,1KS7M@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_5475849_48	292415.Tbd_1756	1.252e-67	232.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,1KRM7@119069|Hydrogenophilales	119069|Hydrogenophilales	O	SmpB protein	-	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS1_k127_5475849_65	1215092.PA6_010_01680	3.902e-37	145.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1YFXA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	ratA	GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS1_k127_5475849_71	1434929.X946_2518	6.177e-18	90.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,1K8F3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
CMS1_k127_5475849_9	62928.azo1580	1.253e-238	745.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KVFJ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS1_k127_5475849_6	1123487.KB892843_gene805	3.933e-282	873.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KVB1@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS1_k127_5475849_67	1318628.MARLIPOL_02715	1.159e-33	138.0	2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5475849_73	1380390.JIAT01000009_gene842	5.427e-13	75.0	COG2044@1|root,COG2044@2|Bacteria,2HRHX@201174|Actinobacteria,4CTI1@84995|Rubrobacteria	84995|Rubrobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS1_k127_5475849_22	296591.Bpro_2645	1.168e-123	402.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria,4AFGR@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CMS1_k127_5475849_60	570952.ATVH01000016_gene2337	5.549e-50	192.0	COG1595@1|root,COG1595@2|Bacteria,1NRNT@1224|Proteobacteria,2TT5K@28211|Alphaproteobacteria,2JZNH@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5475849_74	713586.KB900536_gene1957	1.636e-12	70.0	COG5662@1|root,COG5662@2|Bacteria,1NG37@1224|Proteobacteria,1ST5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_5475849_38	1211115.ALIQ01000156_gene4412	5.568e-83	293.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria,3NCSX@45404|Beijerinckiaceae	28211|Alphaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
CMS1_k127_5475849_63	502025.Hoch_1823	1.622e-46	181.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria,2YV2M@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_5475849_34	502025.Hoch_3258	8.101e-91	310.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,4385Z@68525|delta/epsilon subdivisions,2X3FT@28221|Deltaproteobacteria,2YVWY@29|Myxococcales	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_5475849_58	582744.Msip34_0972	3.955e-56	207.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,2KMTZ@206350|Nitrosomonadales	206350|Nitrosomonadales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
CMS1_k127_5475849_46	1000565.METUNv1_00896	5.043e-72	254.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,2KWDI@206389|Rhodocyclales	206389|Rhodocyclales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_5475849_10	62928.azo1153	2.232e-230	724.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2VJEQ@28216|Betaproteobacteria,2KUQ3@206389|Rhodocyclales	206389|Rhodocyclales	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
CMS1_k127_5475849_21	903818.KI912268_gene1722	1.84e-128	429.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS1_k127_5475849_8	111781.Lepto7376_0265	3.889e-264	836.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1G0Q0@1117|Cyanobacteria,1H8S9@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
CMS1_k127_5475849_61	1175306.GWL_20780	5.26e-49	181.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,474GP@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
CMS1_k127_5475849_45	522306.CAP2UW1_2474	4.186e-73	254.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,2VQK6@28216|Betaproteobacteria,1KQTN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CMS1_k127_5475849_72	1000565.METUNv1_00900	4.273e-13	81.0	2EPNT@1|root,33H9E@2|Bacteria,1NI6Z@1224|Proteobacteria,2VXVE@28216|Betaproteobacteria,2KZ8W@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4936)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4936
CMS1_k127_5475849_55	1071679.BG57_06835	4.169e-60	219.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,1K0KG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
CMS1_k127_5475849_28	1454004.AW11_01221	2.333e-107	358.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,1KPZ8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS1_k127_5475849_54	257310.BB2637	3.347e-60	214.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,3T3YF@506|Alcaligenaceae	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS1_k127_5475849_50	216591.BCAL1963	6.079e-64	229.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,1K0JG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS1_k127_5478378_9	196367.JNFG01000020_gene4498	1.032e-35	145.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,2WH24@28216|Betaproteobacteria,1K5AI@119060|Burkholderiaceae	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_5478378_5	1304878.AUGD01000033_gene3242	9.04e-73	255.0	COG2030@1|root,COG2030@2|Bacteria,1RFHT@1224|Proteobacteria,2UKBG@28211|Alphaproteobacteria,3K446@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_5478378_8	234267.Acid_4411	3.451e-39	151.0	COG0640@1|root,COG0640@2|Bacteria,3Y5ZP@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS1_k127_5478378_3	338969.Rfer_0414	4.513e-85	294.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,2VQH7@28216|Betaproteobacteria,4AGU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS1_k127_5478378_7	338969.Rfer_0415	1.108e-43	171.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,4AICZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Disulfide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
CMS1_k127_5478378_6	1169154.KB897780_gene2447	4.184e-60	213.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
CMS1_k127_5478378_0	1454004.AW11_00495	1.776e-165	542.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
CMS1_k127_5478378_2	1123504.JQKD01000005_gene4750	3.363e-104	345.0	COG1082@1|root,COG1082@2|Bacteria,1R87Z@1224|Proteobacteria,2VQ98@28216|Betaproteobacteria,4AITZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5478378_4	1463820.JOGW01000008_gene1297	8.098e-75	274.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	-	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5478378_1	376733.IT41_12955	4.938e-116	391.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2PWVV@265|Paracoccus	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_5478378_10	645512.GCWU000246_00202	0.0006314	45.0	2EF1S@1|root,338UU@2|Bacteria,3TBI5@508458|Synergistetes	508458|Synergistetes	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
CMS1_k127_5485118_12	395494.Galf_0202	1.711e-89	306.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2VMXN@28216|Betaproteobacteria,44VCC@713636|Nitrosomonadales	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_5485118_20	580332.Slit_0319	6.857e-25	120.0	2ETRW@1|root,33M9C@2|Bacteria,1NEBE@1224|Proteobacteria,2VXIY@28216|Betaproteobacteria,44W11@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5485118_5	264198.Reut_A2773	1.385e-154	499.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_5485118_9	1163617.SCD_n02355	1.053e-115	385.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2VHDW@28216|Betaproteobacteria	28216|Betaproteobacteria	K	permease	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_5485118_17	1266925.JHVX01000015_gene228	3.559e-48	193.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,372SQ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the DnaA family	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
CMS1_k127_5485118_11	1123392.AQWL01000001_gene1461	1.756e-91	305.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,1KRKJ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS1_k127_5485118_4	1454004.AW11_04013	3.712e-158	511.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,1KPSR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
CMS1_k127_5485118_16	1123392.AQWL01000001_gene1419	5.346e-50	184.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,1KSSJ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	-	-	-	-	-	-	-	-	-	-	HPPK
CMS1_k127_5485118_13	1095769.CAHF01000013_gene3343	3.705e-85	289.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,473B3@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
CMS1_k127_5485118_10	640081.Dsui_1470	2.102e-103	355.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,2KV4C@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_5485118_8	1123368.AUIS01000012_gene746	3.056e-120	397.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,2NCPY@225057|Acidithiobacillales	225057|Acidithiobacillales	T	HD domain	-	-	-	ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,Response_reg
CMS1_k127_5485118_7	1123393.KB891316_gene1376	9.342e-126	411.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,1KSE6@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Queuosine biosynthesis protein	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS1_k127_5485118_2	1236959.BAMT01000005_gene199	1.057e-175	556.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,2KKC8@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_5485118_18	1000565.METUNv1_00172	1.202e-38	148.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,2KWNW@206389|Rhodocyclales	206389|Rhodocyclales	U	preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS1_k127_5485118_0	522306.CAP2UW1_2517	6.878e-285	887.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,1KQEU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
CMS1_k127_5485118_6	640081.Dsui_3326	5.723e-126	409.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,2KVVV@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_5485118_1	1454004.AW11_01649	1.8e-199	632.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,1KPT1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
CMS1_k127_5485118_14	279714.FuraDRAFT_1230	3.608e-72	249.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,2KQV8@206351|Neisseriales	206351|Neisseriales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
CMS1_k127_5485118_3	1235457.C404_18330	2.481e-171	547.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,1K159@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS1_k127_5485118_15	497321.C664_10203	2.361e-54	194.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KWI7@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_5485118_19	935948.KE386494_gene944	1.974e-33	134.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_5513722_1	1144319.PMI16_01602	1.915e-151	487.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2VIP8@28216|Betaproteobacteria,472X3@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	PHB de-polymerase C-terminus	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
CMS1_k127_5513722_3	1288826.MSNKSG1_02033	1.773e-65	237.0	COG0697@1|root,COG0697@2|Bacteria,1R6CU@1224|Proteobacteria,1SZQJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_5513722_0	1005048.CFU_3992	2.733e-242	771.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,473Q4@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5513722_2	312153.Pnuc_0450	4.573e-94	323.0	COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,2WHGI@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_551506_0	76114.ebA4448	0.0	1151.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,2KV9I@206389|Rhodocyclales	206389|Rhodocyclales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS1_k127_551506_17	1266925.JHVX01000017_gene19	7.792e-102	340.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,371XT@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS1_k127_551506_22	1121033.AUCF01000001_gene1928	3.223e-69	243.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2TT9A@28211|Alphaproteobacteria,2JSED@204441|Rhodospirillales	204441|Rhodospirillales	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_551506_2	1121033.AUCF01000001_gene1927	1.444e-222	711.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,2JQE2@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_551506_13	1230476.C207_02006	3.514e-141	459.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,3JW51@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_551506_21	264198.Reut_A2767	9.205e-70	247.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,2VMIR@28216|Betaproteobacteria,1K17Z@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
CMS1_k127_551506_6	85643.Tmz1t_2679	3.641e-210	665.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,2KVHB@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_551506_28	1196083.SALWKB12_0496	3.199e-19	90.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,2KRJG@206351|Neisseriales	206351|Neisseriales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS1_k127_551506_1	323848.Nmul_A1040	8.134e-285	890.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,372U6@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Orn/Lys/Arg decarboxylase, C-terminal domain	-	-	4.1.1.19	ko:K01583	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
CMS1_k127_551506_10	76114.ebA5095	5.251e-166	561.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KUN2@206389|Rhodocyclales	206389|Rhodocyclales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_551506_9	1163617.SCD_n02185	2.688e-168	553.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_551506_5	1538295.JY96_16975	1.348e-211	674.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KJ2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS1_k127_551506_8	1437824.BN940_11136	1.971e-170	542.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,3T2CZ@506|Alcaligenaceae	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_551506_3	748247.AZKH_2203	8.466e-221	694.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,2KVEX@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS1_k127_551506_27	324057.Pjdr2_0886	4.046e-32	140.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
CMS1_k127_551506_25	1410620.SHLA_15c000190	1.152e-63	228.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria,4B982@82115|Rhizobiaceae	28211|Alphaproteobacteria	EG	permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_551506_26	1207063.P24_07584	1.819e-59	217.0	COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2TU7N@28211|Alphaproteobacteria,2JS0F@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_551506_12	479434.Sthe_2815	7.199e-154	493.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,27XXF@189775|Thermomicrobia	189775|Thermomicrobia	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS1_k127_551506_16	1333998.M2A_0321	2.044e-111	385.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,4BPR7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_551506_7	1116472.MGMO_122c00140	6.771e-199	628.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XDY1@135618|Methylococcales	135618|Methylococcales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_551506_20	1158756.AQXQ01000009_gene1132	2.06e-76	277.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1WX8R@135613|Chromatiales	135613|Chromatiales	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_551506_24	1095769.CAHF01000015_gene2793	1.461e-65	226.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VRD4@28216|Betaproteobacteria,477DK@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	gloA3	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_551506_14	258594.RPA1654	6.276e-138	445.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TR3G@28211|Alphaproteobacteria,3JQX6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	MA20_21005	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_551506_19	1437824.BN940_01921	4.369e-91	326.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,3T68U@506|Alcaligenaceae	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_551506_11	93220.LV28_03855	4.979e-165	543.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1JZQU@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	bktB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_551506_4	323848.Nmul_A1979	1.44e-214	687.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,372H1@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_551506_23	748247.AZKH_3137	2.11e-67	247.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2VJ2N@28216|Betaproteobacteria,2KVGG@206389|Rhodocyclales	206389|Rhodocyclales	S	synthesis repressor, PhaR	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
CMS1_k127_551506_15	196367.JNFG01000011_gene6118	9.502e-120	388.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,1JZPB@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Acetoacetyl-CoA reductase	phbB	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
CMS1_k127_551506_18	1031711.RSPO_c01713	2.015e-101	332.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1K39S@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	phbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_5517460_50	1123073.KB899242_gene1539	3.297e-41	153.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,1S13N@1236|Gammaproteobacteria,1X4XE@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the GST superfamily	gst5	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
CMS1_k127_5517460_48	452637.Oter_4033	9.037e-43	168.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	yahN	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K03329	-	-	-	-	ko00000,ko02000	2.A.76.1.3	-	-	LysE
CMS1_k127_5517460_10	1123368.AUIS01000019_gene1225	4.482e-150	489.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1T3CM@1236|Gammaproteobacteria,2NDP9@225057|Acidithiobacillales	225057|Acidithiobacillales	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS1_k127_5517460_38	323848.Nmul_A2416	1.309e-62	228.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria,3729Q@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
CMS1_k127_5517460_5	1454004.AW11_00272	2.91e-201	655.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,1KPPG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Single-stranded-DNA-specific exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_5517460_44	414684.RC1_1514	1.17e-52	197.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_5517460_52	1122604.JONR01000032_gene66	3.309e-36	141.0	COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,1SU9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
CMS1_k127_5517460_59	179408.Osc7112_5076	1.588e-08	63.0	COG4249@1|root,COG4249@2|Bacteria,1GQXT@1117|Cyanobacteria,1HBPN@1150|Oscillatoriales	1117|Cyanobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
CMS1_k127_5517460_34	1288494.EBAPG3_13420	9.917e-66	231.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,3731D@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
CMS1_k127_5517460_26	1163617.SCD_n02190	8.139e-93	310.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria	28216|Betaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS1_k127_5517460_43	375286.mma_0839	7.735e-53	194.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,4741T@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS1_k127_5517460_21	323261.Noc_2028	8.553e-105	355.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales	135613|Chromatiales	S	Methyltransferase	-	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
CMS1_k127_5517460_33	1125863.JAFN01000001_gene248	6.33e-71	248.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_5517460_15	1304883.KI912532_gene3069	4.174e-130	419.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,2KV79@206389|Rhodocyclales	206389|Rhodocyclales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
CMS1_k127_5517460_3	261292.Nit79A3_3211	2.404e-286	907.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,372IT@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS1_k127_5517460_20	292415.Tbd_0880	7.301e-118	389.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,1KRGJ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_5517460_55	977880.RALTA_A2237	3.782e-18	87.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,1K9WF@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS1_k127_5517460_11	1000565.METUNv1_02498	6.534e-150	490.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,2KUAN@206389|Rhodocyclales	206389|Rhodocyclales	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_5517460_27	76114.ebA4460	7.115e-92	324.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,2KVPB@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	tst	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_5517460_53	1163617.SCD_n02199	8.281e-31	125.0	2E0X2@1|root,32WE0@2|Bacteria,1R38G@1224|Proteobacteria,2VV4E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
CMS1_k127_5517460_9	1095769.CAHF01000001_gene3436	8.87e-152	490.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,473I6@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS1_k127_5517460_47	1163617.SCD_n01905	5.811e-44	164.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	atpase or kinase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS1_k127_5517460_14	62928.azo1243	2.73e-144	471.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,2KV54@206389|Rhodocyclales	206389|Rhodocyclales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
CMS1_k127_5517460_31	1163617.SCD_n02206	5.234e-80	272.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
CMS1_k127_5517460_6	1266925.JHVX01000013_gene1619	7.81e-197	631.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,37242@32003|Nitrosomonadales	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_5517460_23	999541.bgla_1g06860	6.523e-101	347.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,1K1TT@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_5517460_58	1040987.AZUY01000050_gene3997	1.049e-11	68.0	COG5606@1|root,COG5606@2|Bacteria,1NA3S@1224|Proteobacteria,2UF4K@28211|Alphaproteobacteria,43KY9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
CMS1_k127_5517460_7	1121033.AUCF01000002_gene570	1.149e-183	597.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2JR2R@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_5517460_19	1223521.BBJX01000007_gene1437	5.336e-118	404.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,Response_reg
CMS1_k127_5517460_36	1095769.CAHF01000006_gene1699	1.975e-64	229.0	2CHMN@1|root,340GB@2|Bacteria,1NZBK@1224|Proteobacteria,2W3BS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517460_40	1095769.CAHF01000006_gene1698	1.713e-61	220.0	2AHXP@1|root,318AP@2|Bacteria,1Q03A@1224|Proteobacteria,2W4RE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517460_60	1294142.CINTURNW_0302	4.213e-08	66.0	COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,24MKW@186801|Clostridia,36KAC@31979|Clostridiaceae	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_5517460_2	1121035.AUCH01000015_gene2616	2.051e-318	987.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales	206389|Rhodocyclales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS1_k127_5517460_25	76114.ebA5087	6.563e-93	309.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,2KUU9@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_5517460_24	748247.AZKH_3244	8.864e-95	317.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,2KU7X@206389|Rhodocyclales	206389|Rhodocyclales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS1_k127_5517460_56	1286631.X805_03990	2.869e-14	74.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,1KMR9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0434 family	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
CMS1_k127_5517460_22	1121035.AUCH01000015_gene2611	8.805e-104	349.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,2KU8U@206389|Rhodocyclales	206389|Rhodocyclales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS1_k127_5517460_51	159087.Daro_3209	5.547e-41	155.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,2KWV6@206389|Rhodocyclales	206389|Rhodocyclales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_5517460_30	522306.CAP2UW1_0390	7.209e-82	278.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,1KQS6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	MotA/TolQ/ExbB proton channel family	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_5517460_17	1163617.SCD_n01896	9.64e-125	415.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS1_k127_5517460_35	667632.KB890167_gene1605	1.143e-65	243.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,1K1TA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS1_k127_5517460_42	1057002.KB905371_gene17	2.074e-57	207.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_5517460_41	398767.Glov_1302	2.707e-59	219.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,42SMX@68525|delta/epsilon subdivisions,2WPRJ@28221|Deltaproteobacteria,43SJ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_5517460_49	765912.Thimo_0863	2.827e-41	175.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,1S971@1236|Gammaproteobacteria,1WYN8@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS1_k127_5517460_32	1454004.AW11_02741	6.812e-80	272.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2VQQD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5517460_29	395495.Lcho_1708	7.973e-86	319.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2VP38@28216|Betaproteobacteria,1KN8D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
CMS1_k127_5517460_1	522306.CAP2UW1_2826	0.0	1042.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KQAC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	SNARE associated Golgi protein	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
CMS1_k127_5517460_28	1100720.ALKN01000028_gene2604	6.912e-88	303.0	COG0639@1|root,COG0639@2|Bacteria,1PXN4@1224|Proteobacteria	1224|Proteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_5517460_12	472759.Nhal_1112	2.071e-149	479.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RN94@1236|Gammaproteobacteria,1WXKU@135613|Chromatiales	135613|Chromatiales	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
CMS1_k127_5517460_57	395494.Galf_2052	3.508e-12	74.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2W9TM@28216|Betaproteobacteria,44WMM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_5517460_45	1504672.669784583	4.085e-49	187.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria,4AF81@80864|Comamonadaceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_5517460_8	1265502.KB905947_gene1076	3.76e-164	526.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,4ABHM@80864|Comamonadaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS1_k127_5517460_18	667632.KB890189_gene3268	1.088e-122	402.0	COG0466@1|root,COG0466@2|Bacteria,1MWQ9@1224|Proteobacteria,2VJKY@28216|Betaproteobacteria,1K3YV@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM AAA ATPase central domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
CMS1_k127_5517460_0	1095769.CAHF01000006_gene1959	0.0	1211.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,47292@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_5517460_37	1454004.AW11_03520	1.165e-62	224.0	COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,2VSG3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_5517460_16	309801.trd_0405	1.923e-127	435.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi,27XJU@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_5517460_4	909663.KI867150_gene334	7.557e-207	666.0	COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,42Q1P@68525|delta/epsilon subdivisions,2WM2R@28221|Deltaproteobacteria,2MRSH@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Peptidase M50	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_5517460_13	1298867.AUES01000051_gene4507	1.212e-146	486.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U22Z@28211|Alphaproteobacteria,3K3DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
CMS1_k127_5517460_39	107635.AZUO01000002_gene3758	6.643e-62	243.0	COG2706@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3291@1|root,COG2706@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF5122,HemolysinCabind,Lactonase,Laminin_G_3,Peptidase_M10_C,W_rich_C
CMS1_k127_5517460_46	391613.RTM1035_19806	3.481e-48	199.0	COG0354@1|root,COG2931@1|root,COG3204@1|root,COG4932@1|root,COG0354@2|Bacteria,COG2931@2|Bacteria,COG3204@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46P2B@74030|Roseovarius	28211|Alphaproteobacteria	MQ	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HemolysinCabind,Laminin_G_3,PA14
CMS1_k127_5544860_5	1415780.JPOG01000001_gene174	2.369e-74	257.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,1RWBC@1236|Gammaproteobacteria,1X339@135614|Xanthomonadales	135614|Xanthomonadales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS1_k127_5544860_3	1100720.ALKN01000028_gene2481	3.634e-134	436.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2VJQ2@28216|Betaproteobacteria,4A9SP@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_5544860_1	414684.RC1_0226	2.767e-209	662.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,2JZIB@204441|Rhodospirillales	204441|Rhodospirillales	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS1_k127_5544860_7	1121405.dsmv_2310	5.126e-47	195.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42U0W@68525|delta/epsilon subdivisions,2WQRX@28221|Deltaproteobacteria,2MPQV@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5544860_0	596153.Alide_4194	8.28e-224	713.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VNBU@28216|Betaproteobacteria,4AGM2@80864|Comamonadaceae	28216|Betaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS1_k127_5544860_4	1268622.AVS7_01973	8.496e-123	397.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,4ABCD@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS1_k127_5544860_2	1038869.AXAN01000035_gene2157	1.518e-135	441.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,1K1EZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS1_k127_5544860_6	522306.CAP2UW1_2342	2.262e-55	197.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,1KQCN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS1_k127_5549541_27	266264.Rmet_0061	8.358e-155	495.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1K389@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS1_k127_5549541_60	76114.ebA3048	7.932e-66	235.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KW5V@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_5549541_39	1163617.SCD_n00104	1.443e-108	371.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Aminotransferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_5549541_29	62928.azo0180	1.179e-140	458.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,2KVFQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
CMS1_k127_5549541_58	85643.Tmz1t_0241	5.908e-69	239.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,2KUPW@206389|Rhodocyclales	206389|Rhodocyclales	DM	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CMS1_k127_5549541_24	1163617.SCD_n00209	1.1e-169	545.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria	28216|Betaproteobacteria	F	dihydroorotase	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_5549541_25	1005048.CFU_0802	1.698e-159	510.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,472W3@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_5549541_66	1000565.METUNv1_03050	1.977e-56	201.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,2KWGS@206389|Rhodocyclales	206389|Rhodocyclales	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS1_k127_5549541_86	1304883.KI912532_gene1118	2.869e-26	115.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,2KWP7@206389|Rhodocyclales	206389|Rhodocyclales	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS1_k127_5549541_54	580332.Slit_2935	2.887e-78	269.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,44VSQ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS1_k127_5549541_2	1120999.JONM01000010_gene4085	0.0	1139.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KQCT@206351|Neisseriales	206351|Neisseriales	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
CMS1_k127_5549541_10	640081.Dsui_0657	1.467e-216	692.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
CMS1_k127_5549541_79	62928.azo3455	1.892e-39	155.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,2KX20@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
CMS1_k127_5549541_72	640081.Dsui_0659	7.048e-49	177.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,2KWTI@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
CMS1_k127_5549541_61	1120999.JONM01000010_gene4089	5.267e-63	220.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KTJ0@206351|Neisseriales	206351|Neisseriales	KT	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_5549541_82	1144342.PMI40_02830	1.798e-32	126.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,474ZG@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Rubredoxin	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
CMS1_k127_5549541_44	640081.Dsui_0662	1.299e-104	347.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,2KVE8@206389|Rhodocyclales	206389|Rhodocyclales	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS1_k127_5549541_67	279714.FuraDRAFT_3377	9.559e-55	213.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,2KR43@206351|Neisseriales	206351|Neisseriales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_5549541_16	582744.Msip34_2802	3.363e-195	616.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,2KKPE@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_5549541_13	1121035.AUCH01000006_gene759	5.747e-200	634.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,2KUHE@206389|Rhodocyclales	206389|Rhodocyclales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_5549541_55	305700.B447_11307	9.485e-76	271.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,2KUYM@206389|Rhodocyclales	206389|Rhodocyclales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS1_k127_5549541_47	748247.AZKH_3828	4.139e-93	314.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,2KUFF@206389|Rhodocyclales	206389|Rhodocyclales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS1_k127_5549541_48	640081.Dsui_0445	3.085e-86	295.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,2KUYN@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0810 Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_5549541_11	640081.Dsui_0446	1.745e-204	653.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,2KVMW@206389|Rhodocyclales	206389|Rhodocyclales	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
CMS1_k127_5549541_73	1163617.SCD_n00215	1.975e-47	191.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	esterase	yqiA	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
CMS1_k127_5549541_17	292415.Tbd_2572	1.141e-189	603.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,1KSMD@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Mur ligase family, catalytic domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5549541_74	305700.B447_02998	5.513e-47	179.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,2KUIR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549541_80	1123392.AQWL01000002_gene1938	3.266e-38	149.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,1KT10@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_5549541_63	266264.Rmet_3063	9.674e-61	214.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1K5S0@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS1_k127_5549541_68	265072.Mfla_0025	1.221e-52	196.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,2KMQS@206350|Nitrosomonadales	206350|Nitrosomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS1_k127_5549541_8	1198452.Jab_2c28910	1.503e-253	786.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,472TI@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS1_k127_5549541_52	667632.KB890167_gene1487	2.376e-81	287.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,1K3BV@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS1_k127_5549541_77	522306.CAP2UW1_4140	2.549e-40	160.0	COG1273@1|root,COG1273@2|Bacteria,1QVC4@1224|Proteobacteria,2WGPK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
CMS1_k127_5549541_33	522306.CAP2UW1_4139	1.067e-134	435.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,1KPSB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_5549541_76	1121004.ATVC01000014_gene2032	1.021e-41	167.0	COG0537@1|root,COG0537@2|Bacteria,1N422@1224|Proteobacteria,2VT5W@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS1_k127_5549541_41	1000565.METUNv1_03539	2.994e-106	351.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,2KUKD@206389|Rhodocyclales	206389|Rhodocyclales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_5549541_15	292415.Tbd_0237	1.458e-195	621.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,1KSHB@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS1_k127_5549541_90	62928.azo3737	2.6e-17	86.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,2VVR4@28216|Betaproteobacteria,2KX84@206389|Rhodocyclales	206389|Rhodocyclales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
CMS1_k127_5549541_56	1123487.KB892834_gene2602	3.536e-75	261.0	2C5U9@1|root,318BZ@2|Bacteria,1RK4D@1224|Proteobacteria,2VTKM@28216|Betaproteobacteria,2KZTH@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS1_k127_5549541_65	62928.azo3739	1.105e-56	201.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KWCQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
CMS1_k127_5549541_22	1236959.BAMT01000005_gene112	4.975e-173	553.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,2KKII@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_5549541_81	748247.AZKH_2910	8.188e-34	138.0	COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2VV8Y@28216|Betaproteobacteria,2KWY8@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS1_k127_5549541_43	76114.ebA727	4.525e-105	360.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,2KY7V@206389|Rhodocyclales	28216|Betaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.25,6.2.1.27,6.2.1.37	ko:K04110,ko:K20458	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01300,R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding
CMS1_k127_5549541_49	1179778.PMM47T1_16895	3.564e-84	284.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
CMS1_k127_5549541_50	414684.RC1_2508	1.162e-83	282.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,2JRTT@204441|Rhodospirillales	204441|Rhodospirillales	O	maleylacetoacetate isomerase	maiA	-	5.2.1.4	ko:K01801	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	GST_C_2,GST_C_3,GST_N,GST_N_3
CMS1_k127_5549541_51	76114.ebA715	4.737e-82	286.0	COG1309@1|root,COG1309@2|Bacteria,1R4VA@1224|Proteobacteria,2VT2X@28216|Betaproteobacteria,2KYUM@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_5549541_28	76114.ebA722	7.687e-153	485.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,2KYCR@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_5549541_42	76114.ebA723	2.516e-105	347.0	COG1028@1|root,COG1028@2|Bacteria,1RCD5@1224|Proteobacteria,2W04R@28216|Betaproteobacteria,2KXRA@206389|Rhodocyclales	206389|Rhodocyclales	IQ	KR domain	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS1_k127_5549541_87	159087.Daro_3954	1.43e-23	114.0	COG2199@1|root,COG2703@1|root,COG5000@1|root,COG2199@2|Bacteria,COG2703@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria,2VQEF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,dCache_1
CMS1_k127_5549541_89	1144319.PMI16_04564	5.336e-21	106.0	COG0824@1|root,COG0824@2|Bacteria,1RG6B@1224|Proteobacteria,2VTAU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	-Thioesterase	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
CMS1_k127_5549541_30	1232410.KI421426_gene1390	2.87e-138	455.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42RJK@68525|delta/epsilon subdivisions,2WNEM@28221|Deltaproteobacteria,43UWP@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5549541_62	497321.C664_11865	3.8e-61	214.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria,2KWUC@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_5549541_0	292415.Tbd_0234	0.0	1678.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,1KRGX@119069|Hydrogenophilales	119069|Hydrogenophilales	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS1_k127_5549541_83	323848.Nmul_A1031	2.305e-32	147.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,2VU8X@28216|Betaproteobacteria,373CU@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF423)	ygdD	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS1_k127_5549541_93	1452718.JBOY01000189_gene2858	1.836e-06	60.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cobalamin synthesis protein, P47K	yeiR	GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
CMS1_k127_5549541_21	261292.Nit79A3_0469	5.071e-180	576.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,3728D@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_5549541_14	1131553.JIBI01000071_gene2157	2.658e-196	622.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,3728D@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_5549541_12	580332.Slit_2942	7.142e-202	638.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,44W83@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_5549541_36	305700.B447_02276	1.439e-123	409.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,2KV57@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
CMS1_k127_5549541_9	640081.Dsui_0810	6.749e-218	697.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KV2P@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_5549541_71	395019.Bmul_3119	4.116e-50	186.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,1K464@119060|Burkholderiaceae	28216|Betaproteobacteria	S	signal peptide protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
CMS1_k127_5549541_35	640081.Dsui_0812	2.462e-127	420.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,2KV06@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
CMS1_k127_5549541_40	305700.B447_05670	5.748e-107	355.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,2KVNV@206389|Rhodocyclales	206389|Rhodocyclales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_5549541_59	1485544.JQKP01000002_gene1574	2.603e-66	229.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,44VPM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_5549541_45	1163617.SCD_n00008	3.601e-104	352.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_5549541_37	1000565.METUNv1_03060	3.067e-115	382.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,2KUP7@206389|Rhodocyclales	206389|Rhodocyclales	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_5549541_3	887898.HMPREF0551_2142	0.0	1091.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1K0Y7@119060|Burkholderiaceae	28216|Betaproteobacteria	L	dna topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
CMS1_k127_5549541_1	1288494.EBAPG3_7950	0.0	1217.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,3725J@32003|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_5549541_31	159087.Daro_0002	1.84e-137	446.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,2KV12@206389|Rhodocyclales	206389|Rhodocyclales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS1_k127_5549541_20	1266925.JHVX01000008_gene367	4.457e-182	579.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,372M3@32003|Nitrosomonadales	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_5549541_91	232721.Ajs_4143	5.418e-12	66.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria,4AFCB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_5549541_92	498211.CJA_3825	1.171e-09	64.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1FHHA@10|Cellvibrio	1236|Gammaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS1_k127_5549541_85	211114.JOEF01000003_gene2837	3.39e-29	119.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS1_k127_5549541_18	1288494.EBAPG3_8000	9.913e-189	604.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,371S5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS1_k127_5549541_26	305700.B447_02311	1.199e-157	509.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,2KVKC@206389|Rhodocyclales	206389|Rhodocyclales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS1_k127_5549541_53	279714.FuraDRAFT_0380	7.239e-79	275.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2VM18@28216|Betaproteobacteria,2KSVR@206351|Neisseriales	206351|Neisseriales	S	Pfam:AmoA	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
CMS1_k127_5549541_5	1123354.AUDR01000001_gene2029	1.244e-290	917.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CMS1_k127_5549541_4	640081.Dsui_0846	1.099e-303	942.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,2KUAA@206389|Rhodocyclales	206389|Rhodocyclales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_5549541_64	1163617.SCD_n03030	4.501e-58	213.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS1_k127_5549541_38	1266925.JHVX01000008_gene372	4.558e-114	374.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,371Z8@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_5549541_46	305700.B447_05875	1.205e-96	330.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,2KU8M@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the ParB family	spoOJ	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_5549541_88	323848.Nmul_A0303	8.887e-23	104.0	COG3312@1|root,COG3312@2|Bacteria,1NQF1@1224|Proteobacteria,2W4BE@28216|Betaproteobacteria,373BY@32003|Nitrosomonadales	28216|Betaproteobacteria	C	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
CMS1_k127_5549541_34	265072.Mfla_2750	2.223e-130	420.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,2KKB3@206350|Nitrosomonadales	206350|Nitrosomonadales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS1_k127_5549541_78	323848.Nmul_A0305	2.877e-40	151.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,373AG@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS1_k127_5549541_69	1266925.JHVX01000005_gene1935	2.297e-51	188.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,372ZX@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS1_k127_5549541_75	1123367.C666_13770	3.183e-42	160.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,2KWKN@206389|Rhodocyclales	206389|Rhodocyclales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS1_k127_5549541_6	395019.Bmul_0104	8.581e-279	863.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,1K1JD@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS1_k127_5549541_32	323848.Nmul_A0309	2.254e-137	441.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,371MG@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS1_k127_5549541_7	887898.HMPREF0551_2052	1.033e-266	825.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1K2Y1@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_5549541_70	75379.Tint_2753	9.426e-51	183.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KKT3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS1_k127_5549541_57	1469245.JFBG01000037_gene1851	1.031e-69	242.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,1S43F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	dehydratase	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
CMS1_k127_5549541_19	94624.Bpet0851	8.662e-184	580.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKWF@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5549541_23	1392838.AWNM01000035_gene284	2.18e-170	546.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VMYW@28216|Betaproteobacteria,3T3PZ@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_5551909_22	522306.CAP2UW1_2397	2.459e-08	60.0	28H91@1|root,2Z7KU@2|Bacteria,1R4NB@1224|Proteobacteria,2VS45@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5551909_12	556269.ACDQ01000017_gene906	2.932e-46	187.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,474CZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	NUDIX domain	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
CMS1_k127_5551909_21	1121382.JQKG01000052_gene2190	6.502e-22	102.0	COG2732@1|root,COG2732@2|Bacteria	2|Bacteria	K	(Barnase) inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
CMS1_k127_5551909_17	1907.SGLAU_05890	1.24e-32	130.0	COG4290@1|root,COG4290@2|Bacteria,2IHPV@201174|Actinobacteria	201174|Actinobacteria	F	Ribonuclease	-	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
CMS1_k127_5551909_1	1095769.CAHF01000014_gene2933	3.32e-281	874.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,473I1@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_5551909_5	1144342.PMI40_04765	2.764e-92	306.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,4761R@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS1_k127_5551909_19	305700.B447_16557	1.732e-28	124.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,2KX0R@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_5551909_10	686340.Metal_2228	6.764e-50	190.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1XGBY@135618|Methylococcales	135618|Methylococcales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_5551909_7	1005048.CFU_0475	2.266e-56	199.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,4744R@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS1_k127_5551909_4	1123392.AQWL01000018_gene70	8.592e-126	417.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,1KRDC@119069|Hydrogenophilales	119069|Hydrogenophilales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_5551909_0	557598.LHK_01605	0.0	1442.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KPRX@206351|Neisseriales	206351|Neisseriales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_5551909_8	1254432.SCE1572_29970	4.971e-53	194.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,42T50@68525|delta/epsilon subdivisions,2WPVV@28221|Deltaproteobacteria,2YUY1@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
CMS1_k127_5551909_6	1144275.COCOR_03628	9.258e-61	222.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,431FI@68525|delta/epsilon subdivisions,2WX1E@28221|Deltaproteobacteria,2YV8K@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_5551909_9	1297742.A176_01943	2.134e-50	196.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,42UJU@68525|delta/epsilon subdivisions,2WQI6@28221|Deltaproteobacteria,2YYTJ@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_5551909_23	1096546.WYO_1714	1.312e-05	55.0	COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,2TS9Q@28211|Alphaproteobacteria,1JQWF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
CMS1_k127_5551909_20	1121438.JNJA01000005_gene1024	4.407e-25	113.0	COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,43D2A@68525|delta/epsilon subdivisions,2WJNX@28221|Deltaproteobacteria,2MA4Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
CMS1_k127_5551909_15	1532557.JL37_26935	3.486e-39	157.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VQID@28216|Betaproteobacteria,3T48U@506|Alcaligenaceae	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS1_k127_5551909_2	640081.Dsui_2297	1.507e-264	831.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,2KVQH@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_5551909_11	1089552.KI911559_gene939	1.319e-49	190.0	COG0385@1|root,COG0385@2|Bacteria,1MVXH@1224|Proteobacteria,2TTE0@28211|Alphaproteobacteria,2JSCP@204441|Rhodospirillales	204441|Rhodospirillales	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
CMS1_k127_5551909_13	1380391.JIAS01000001_gene2808	9.72e-46	178.0	COG4700@1|root,COG4700@2|Bacteria,1R577@1224|Proteobacteria,2TU7Z@28211|Alphaproteobacteria,2JXF0@204441|Rhodospirillales	28211|Alphaproteobacteria	S	protein conserved in bacteria containing a divergent form of TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,TPR_16,TPR_19,TPR_4
CMS1_k127_5551909_16	748247.AZKH_4465	1.287e-36	145.0	COG3576@1|root,COG3576@2|Bacteria,1N8Z5@1224|Proteobacteria,2VVVW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5551909_3	748247.AZKH_4464	1.894e-162	524.0	COG2203@1|root,COG3576@1|root,COG2203@2|Bacteria,COG3576@2|Bacteria,1PP8V@1224|Proteobacteria,2VKHH@28216|Betaproteobacteria,2KXR2@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
CMS1_k127_5551909_14	748247.AZKH_4461	6.833e-45	174.0	COG2010@1|root,COG2010@2|Bacteria,1N0EF@1224|Proteobacteria,2VT6G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_5551909_18	323848.Nmul_A1524	4.643e-31	124.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VQ9I@28216|Betaproteobacteria,371PA@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_563771_2	1265502.KB905931_gene1710	1.032e-58	212.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,4AEJE@80864|Comamonadaceae	28216|Betaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_563771_0	640081.Dsui_2434	0.0	1074.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,2KVUA@206389|Rhodocyclales	206389|Rhodocyclales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS1_k127_563771_1	375286.mma_1247	1.596e-188	599.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,472KW@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Aminotransferase class I and II	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5662713_13	1005048.CFU_2433	3.455e-08	59.0	2EP1T@1|root,315BD@2|Bacteria,1PVCW@1224|Proteobacteria,2WB83@28216|Betaproteobacteria,4757Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5662713_10	525897.Dbac_0908	7.805e-50	188.0	COG1403@1|root,COG1432@1|root,COG1403@2|Bacteria,COG1432@2|Bacteria,1REF0@1224|Proteobacteria,42RN2@68525|delta/epsilon subdivisions,2WNV8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5662713_2	580332.Slit_0525	4.837e-169	542.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PPH1@1224|Proteobacteria,2W9GU@28216|Betaproteobacteria,44WKA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
CMS1_k127_5662713_8	580332.Slit_1446	4.084e-67	240.0	COG0492@1|root,COG0492@2|Bacteria,1R12A@1224|Proteobacteria,2WHYF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5662713_1	580332.Slit_1447	3.066e-232	735.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2WHYC@28216|Betaproteobacteria,44WNC@713636|Nitrosomonadales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
CMS1_k127_5662713_7	1049564.TevJSym_ar00350	1.065e-72	269.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,1RQ6X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5662713_14	580332.Slit_0867	8.158e-08	60.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5662713_5	1123487.KB892863_gene1982	4.133e-94	339.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5662713_4	1349785.BAUG01000039_gene2104	3.73e-116	383.0	COG4122@1|root,COG4122@2|Bacteria,4NJV1@976|Bacteroidetes,1HYRV@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS1_k127_5662713_6	1121033.AUCF01000001_gene2167	1.226e-73	261.0	COG0477@1|root,COG2814@2|Bacteria,1R7QS@1224|Proteobacteria,2TUXM@28211|Alphaproteobacteria,2JS4J@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5662713_12	765911.Thivi_2721	2.972e-41	156.0	COG0607@1|root,COG0607@2|Bacteria,1RJQ6@1224|Proteobacteria,1S7FR@1236|Gammaproteobacteria,1X2JR@135613|Chromatiales	135613|Chromatiales	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_5662713_0	1095769.CAHF01000022_gene195	3.139e-249	782.0	COG0501@1|root,COG0501@2|Bacteria,1NA37@1224|Proteobacteria,2VIMA@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_5662713_9	1366050.N234_02650	4.576e-64	235.0	COG2188@1|root,COG2188@2|Bacteria,1R790@1224|Proteobacteria,2VKB7@28216|Betaproteobacteria,1K5ED@119060|Burkholderiaceae	28216|Betaproteobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
CMS1_k127_5662713_11	543913.D521_1332	9.552e-42	156.0	COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,2VU0R@28216|Betaproteobacteria	28216|Betaproteobacteria	G	SAF	-	-	4.4.1.24	ko:K16845	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	SAF
CMS1_k127_5662713_3	1472716.KBK24_0136215	2.136e-168	534.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VK3Y@28216|Betaproteobacteria,1K3JP@119060|Burkholderiaceae	28216|Betaproteobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.4.1.24	ko:K16846	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	GD_AH_C
CMS1_k127_5745761_4	522306.CAP2UW1_0634	4.652e-136	452.0	COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_5745761_15	1121035.AUCH01000003_gene1203	3.867e-52	192.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,2VR8U@28216|Betaproteobacteria,2KWCN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_5745761_0	640081.Dsui_1383	4.523e-221	704.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,2KUCM@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS1_k127_5745761_3	640081.Dsui_1382	2.516e-139	454.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,2KV61@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS1_k127_5745761_14	7460.GB43322-PA	3.509e-54	196.0	COG0794@1|root,2RDRP@2759|Eukaryota,3A4CC@33154|Opisthokonta,3BU6P@33208|Metazoa,3DRBD@33213|Bilateria,42239@6656|Arthropoda,3SQJQ@50557|Insecta	33208|Metazoa	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS1_k127_5745761_18	1163617.SCD_n00560	1.685e-28	128.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
CMS1_k127_5745761_17	1454004.AW11_03611	1.712e-33	137.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,1KQYU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
CMS1_k127_5745761_6	1454004.AW11_03665	2.049e-113	370.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,1KQ9S@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Lipopolysaccharide export system ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_5745761_1	1348657.M622_00620	2.958e-165	535.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,2KV3Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN1	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS1_k127_5745761_16	1000565.METUNv1_03641	5.835e-37	142.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,2KWTT@206389|Rhodocyclales	206389|Rhodocyclales	J	sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS1_k127_5745761_12	640081.Dsui_0702	2.327e-60	214.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,2KW4R@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS1_k127_5745761_9	640081.Dsui_0701	4.758e-97	326.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,2KVU0@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CMS1_k127_5745761_8	497321.C664_03872	4.537e-99	331.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,2KUWU@206389|Rhodocyclales	206389|Rhodocyclales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS1_k127_5745761_13	640081.Dsui_0994	2.923e-56	205.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,2VSA4@28216|Betaproteobacteria,2KWC8@206389|Rhodocyclales	206389|Rhodocyclales	S	peptidase S16	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
CMS1_k127_5745761_5	85643.Tmz1t_0443	1.131e-119	394.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,2KUFV@206389|Rhodocyclales	206389|Rhodocyclales	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS1_k127_5745761_2	1156919.QWC_21879	2.062e-146	476.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VM4Z@28216|Betaproteobacteria,3T8WW@506|Alcaligenaceae	28216|Betaproteobacteria	S	Metal-dependent amidase aminoacylase carboxypeptidase	yxeP_2	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_5745761_10	105559.Nwat_2753	1.996e-82	292.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1WX4U@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
CMS1_k127_5745761_7	1000565.METUNv1_03446	2.577e-104	356.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,2KWW5@206389|Rhodocyclales	206389|Rhodocyclales	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
CMS1_k127_57717_0	189753.AXAS01000032_gene4142	1.425e-157	517.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JS0R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	repeat protein	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_57717_5	1304883.KI912532_gene1360	5.104e-71	246.0	COG3108@1|root,COG3108@2|Bacteria	2|Bacteria	S	Peptidase M15	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Peptidase_M15_3
CMS1_k127_57717_3	331869.BAL199_27751	1.914e-82	281.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,4BS4B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_57717_6	1354722.JQLS01000004_gene4234	5.232e-57	209.0	COG1024@1|root,COG1024@2|Bacteria,1MXEN@1224|Proteobacteria,2TTIH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_57717_7	580332.Slit_1469	4.02e-46	187.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2VHDJ@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	TIGRFAM outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,TIG
CMS1_k127_57717_2	580332.Slit_1471	3.334e-83	286.0	2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,2VT7Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_57717_4	365044.Pnap_3813	7.191e-76	266.0	COG3181@1|root,COG3181@2|Bacteria,1NSWQ@1224|Proteobacteria,2VHX6@28216|Betaproteobacteria,4AC2C@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_57717_1	1163617.SCD_n02203	1.469e-92	309.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,2VQJE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
CMS1_k127_57717_8	522306.CAP2UW1_2076	5.775e-40	159.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS1_k127_5795966_49	1348657.M622_15705	8.88e-10	60.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,2KUR3@206389|Rhodocyclales	206389|Rhodocyclales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
CMS1_k127_5795966_45	1123393.KB891316_gene1691	5.577e-17	83.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,1KRWJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DNA gyrase inhibitor YacG	-	-	-	-	-	-	-	-	-	-	-	-	YacG
CMS1_k127_5795966_31	1163617.SCD_n02471	1.402e-100	351.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
CMS1_k127_5795966_25	85643.Tmz1t_3660	5.417e-115	379.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,2KUQI@206389|Rhodocyclales	206389|Rhodocyclales	S	ATPase (AAA	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
CMS1_k127_5795966_11	864051.BurJ1DRAFT_1243	7.618e-154	501.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria,1KJ4N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS1_k127_5795966_0	1000565.METUNv1_00127	0.0	1259.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KVJC@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_5795966_34	1288494.EBAPG3_28070	4.937e-97	327.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,371UP@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS1_k127_5795966_48	388051.AUFE01000028_gene5029	4.03e-12	73.0	COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,2VWI9@28216|Betaproteobacteria,1K86K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS1_k127_5795966_20	159087.Daro_3492	1.478e-139	451.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,2KU6A@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
CMS1_k127_5795966_15	1304883.KI912532_gene1577	6.509e-149	486.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,2KV6H@206389|Rhodocyclales	206389|Rhodocyclales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_5795966_6	1286093.C266_15866	4.763e-198	624.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,1K1ZW@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_5795966_39	582744.Msip34_0464	1.595e-58	212.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,2KKS9@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS1_k127_5795966_26	1485544.JQKP01000002_gene1623	8.692e-115	392.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS1_k127_5795966_27	1163617.SCD_n02483	8.35e-110	364.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS1_k127_5795966_3	93220.LV28_11445	1.543e-220	697.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,1K0U8@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5795966_19	748247.AZKH_3726	3.454e-140	474.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,2KVGS@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS1_k127_5795966_13	582744.Msip34_0459	4.877e-150	494.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KM9S@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS1_k127_5795966_16	1485544.JQKP01000002_gene1628	8.877e-147	495.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,44V6N@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_5795966_9	497321.C664_17000	3.342e-180	581.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,2KVME@206389|Rhodocyclales	206389|Rhodocyclales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS1_k127_5795966_22	1123367.C666_14680	9.886e-132	447.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,2KVHS@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5795966_18	1485544.JQKP01000002_gene1631	1.64e-141	468.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,44VE4@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5795966_5	1163617.SCD_n02491	5.355e-213	684.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_5795966_44	1266925.JHVX01000005_gene1878	2.999e-19	95.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria,373NV@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
CMS1_k127_5795966_24	1000565.METUNv1_00147	1.678e-116	383.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,2KUQH@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS1_k127_5795966_42	1163617.SCD_n02494	1.218e-41	159.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS1_k127_5795966_8	1121861.KB899915_gene1911	3.066e-181	583.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2TU6Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5795966_21	543728.Vapar_0782	2.501e-136	446.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2VKG2@28216|Betaproteobacteria,4AJBI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	ybiC	-	-	ko:K13574	-	-	-	-	ko00000,ko01000	-	-	-	Ldh_2
CMS1_k127_5795966_2	1207063.P24_05877	4.803e-281	873.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JQ5K@204441|Rhodospirillales	204441|Rhodospirillales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82,4.2.1.9	ko:K01687,ko:K22186	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_5795966_35	1100721.ALKO01000016_gene1439	4.733e-96	321.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VK64@28216|Betaproteobacteria,4ACSY@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_5795966_33	1380394.JADL01000005_gene5415	8.295e-100	336.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TTJV@28211|Alphaproteobacteria,2JPXD@204441|Rhodospirillales	204441|Rhodospirillales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.215	ko:K22229	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01739	RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_5795966_32	1411123.JQNH01000001_gene2712	7.543e-100	350.0	COG2358@1|root,COG2358@2|Bacteria,1NSZ5@1224|Proteobacteria,2U3NZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system periplasmic component	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_5795966_4	1411123.JQNH01000001_gene2713	5.505e-217	691.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
CMS1_k127_5795966_51	497321.C664_13719	9.893e-06	50.0	2C8AW@1|root,33ACI@2|Bacteria,1NGTZ@1224|Proteobacteria,2VXMK@28216|Betaproteobacteria,2KXIX@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5795966_23	580332.Slit_1573	6.421e-120	394.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,44W51@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART band 7 protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
CMS1_k127_5795966_46	859657.RPSI07_1939	1.837e-14	80.0	COG1585@1|root,COG1585@2|Bacteria,1N474@1224|Proteobacteria,2VWDX@28216|Betaproteobacteria,1K7AI@119060|Burkholderiaceae	28216|Betaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS1_k127_5795966_38	420662.Mpe_A0408	1.635e-67	239.0	COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2VRTF@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	2-Keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS1_k127_5795966_12	94624.Bpet0819	3.7e-152	491.0	COG1804@1|root,COG1804@2|Bacteria,1MU4A@1224|Proteobacteria,2VKDA@28216|Betaproteobacteria,3T29V@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.22	ko:K18289	ko00660,map00660	-	R02407,R03154	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_transf_3
CMS1_k127_5795966_52	1304275.C41B8_06502	6.526e-05	55.0	2C99D@1|root,2Z7Y8@2|Bacteria,1R5JY@1224|Proteobacteria,1SI3Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
CMS1_k127_5795966_50	1225785.CM001983_gene2059	2.288e-06	59.0	COG2223@1|root,COG2223@2|Bacteria,1QUDK@1224|Proteobacteria	1224|Proteobacteria	P	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5795966_17	1125863.JAFN01000001_gene850	1.296e-141	463.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714,ko:K07715	ko02020,ko02024,map02020,map02024	M00500,M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5795966_36	265072.Mfla_0913	1.774e-92	322.0	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,2KKG4@206350|Nitrosomonadales	206350|Nitrosomonadales	T	His Kinase A (phospho-acceptor) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS1_k127_5795966_41	75379.Tint_1386	5.905e-51	186.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,1KM46@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
CMS1_k127_5795966_7	323848.Nmul_A1964	4.918e-182	576.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,372I8@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_5795966_28	1366050.N234_16795	1.809e-109	357.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,1K38F@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS1_k127_5795966_10	267608.RSc2379	3.789e-172	546.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1K0I7@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS1_k127_5795966_1	1123487.KB892844_gene854	3.252e-303	967.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,2KUGX@206389|Rhodocyclales	206389|Rhodocyclales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS1_k127_5795966_37	580332.Slit_1269	4.135e-73	262.0	COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria,44VWF@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PEGA
CMS1_k127_5795966_43	580332.Slit_1270	4.082e-25	111.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5795966_30	395494.Galf_1181	3.675e-101	343.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS1_k127_5795966_14	272134.KB731324_gene2983	2.4e-149	484.0	COG1960@1|root,COG1960@2|Bacteria,1G4X4@1117|Cyanobacteria	1117|Cyanobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5795966_29	381666.H16_B0937	1.991e-106	356.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria,1K2I8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
CMS1_k127_5795966_40	195250.CM001776_gene2926	4.75e-57	214.0	COG1732@1|root,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1H09I@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter (QAT) family	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
CMS1_k127_5795966_47	1385935.N836_36145	3.637e-13	79.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_5810478_0	1123355.JHYO01000016_gene1850	1.22e-231	727.0	COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,2TVMQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS1_k127_5810478_1	1095769.CAHF01000006_gene1762	1.737e-209	660.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHQD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Aldehyde dehydrogenase	betB	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_5810478_2	1095769.CAHF01000006_gene1763	2.533e-160	513.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2VIJB@28216|Betaproteobacteria,4724J@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5810478_4	395495.Lcho_0045	8.968e-102	360.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
CMS1_k127_5810478_3	331869.BAL199_12961	6.626e-112	370.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VEXI@28211|Alphaproteobacteria,4BS72@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_5810478_5	189753.AXAS01000041_gene2534	1.104e-60	222.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS1_k127_5810478_7	1216007.AOPM01000053_gene2307	3.485e-07	62.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,2Q1WT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_5810478_6	472759.Nhal_3549	7.425e-56	203.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1WYN6@135613|Chromatiales	135613|Chromatiales	K	SMART cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5823798_2	1366050.N234_06075	8.926e-188	605.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2W0W2@28216|Betaproteobacteria,1K15H@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5823798_11	935848.JAEN01000001_gene3531	9.736e-77	265.0	COG1028@1|root,COG1028@2|Bacteria,1PUM1@1224|Proteobacteria,2TVKY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5823798_8	1197906.CAJQ02000024_gene1322	3.938e-99	329.0	COG1024@1|root,COG1024@2|Bacteria,1MVJJ@1224|Proteobacteria,2U0AD@28211|Alphaproteobacteria,3K2FA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_5823798_1	94624.Bpet1239	1.17e-231	730.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2W94J@28216|Betaproteobacteria,3T62S@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K12507	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5823798_5	1304878.AUGD01000017_gene1037	1.368e-139	452.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2U0ZZ@28211|Alphaproteobacteria,3JWVZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661,ko:K07536	ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220	M00116,M00540	R05592,R07263	RC01429,RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_5823798_3	1038859.AXAU01000013_gene6493	3.464e-162	527.0	COG0683@1|root,COG0683@2|Bacteria,1MVZR@1224|Proteobacteria,2TRRP@28211|Alphaproteobacteria,3JW77@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_5823798_7	1038859.AXAU01000013_gene6492	7.047e-108	357.0	COG0559@1|root,COG0559@2|Bacteria,1MYEW@1224|Proteobacteria,2TQQZ@28211|Alphaproteobacteria,3JUB8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_5823798_9	1279038.KB907355_gene2098	2.39e-95	334.0	COG4177@1|root,COG4177@2|Bacteria,1QF6I@1224|Proteobacteria,2TRTF@28211|Alphaproteobacteria,2JRVM@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_5823798_10	331869.BAL199_26212	1.434e-89	303.0	COG0411@1|root,COG0411@2|Bacteria,1R5MA@1224|Proteobacteria,2TV7Q@28211|Alphaproteobacteria,4BRYV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_5823798_12	1038859.AXAU01000013_gene6489	3.939e-75	258.0	COG0410@1|root,COG0410@2|Bacteria,1R5HF@1224|Proteobacteria,2TV1S@28211|Alphaproteobacteria,3JWZ6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_5823798_6	1411123.JQNH01000001_gene2684	4.85e-109	369.0	COG4336@1|root,COG4336@2|Bacteria,1MW52@1224|Proteobacteria,2TST8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the D-glutamate cyclase family	MA20_16485	-	-	-	-	-	-	-	-	-	-	-	DUF1445
CMS1_k127_5823798_4	713586.KB900536_gene1872	3.151e-149	483.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,1WXVR@135613|Chromatiales	135613|Chromatiales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
CMS1_k127_5823798_14	340177.Cag_2005	9.206e-13	73.0	COG2863@1|root,COG2863@2|Bacteria,1FE7R@1090|Chlorobi	1090|Chlorobi	C	PFAM cytochrome c, class I	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	-
CMS1_k127_5823798_13	517418.Ctha_2273	9.294e-34	139.0	COG0664@1|root,COG0664@2|Bacteria,1FF3S@1090|Chlorobi	1090|Chlorobi	T	Popeye protein conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Popeye
CMS1_k127_5823798_0	443143.GM18_0105	2.417e-235	748.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QGH@68525|delta/epsilon subdivisions,2WKTM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM multicopper oxidase type 2	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
CMS1_k127_5847521_0	568706.BN118_1192	2.572e-167	534.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,3T24Z@506|Alcaligenaceae	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
CMS1_k127_5847521_3	1163617.SCD_n01786	1.622e-130	429.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS1_k127_5847521_14	765910.MARPU_12270	3.448e-05	57.0	2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5847521_7	519989.ECTPHS_00080	3.5e-76	262.0	COG0518@1|root,COG0518@2|Bacteria,1MYXC@1224|Proteobacteria,1SJVW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	GMP synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5847521_4	1121035.AUCH01000001_gene1900	1.897e-128	417.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria,2KU9Y@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5847521_11	519989.ECTPHS_00070	1.056e-32	132.0	2FCC0@1|root,344FM@2|Bacteria,1NZRH@1224|Proteobacteria,1SRBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5847521_1	323848.Nmul_A2116	1.036e-159	515.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,37237@32003|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM Major facilitator superfamily	lplT	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5847521_5	1123368.AUIS01000007_gene2763	8.798e-124	413.0	COG0667@1|root,COG0667@2|Bacteria,1RK6Z@1224|Proteobacteria,1SKN5@1236|Gammaproteobacteria,2NC9A@225057|Acidithiobacillales	225057|Acidithiobacillales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5847521_13	396588.Tgr7_2165	1.529e-22	102.0	2CJFI@1|root,32XF5@2|Bacteria,1N623@1224|Proteobacteria,1SRCG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5847521_12	1279019.ARQK01000051_gene1385	2.204e-25	115.0	2FIAJ@1|root,34A2Z@2|Bacteria,1P28Q@1224|Proteobacteria,1SSYY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5847521_6	395019.Bmul_1234	4.978e-84	293.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,1K1QM@119060|Burkholderiaceae	28216|Betaproteobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_5847521_9	292415.Tbd_1724	4.534e-42	159.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,1KRRR@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS1_k127_5847521_8	1123392.AQWL01000008_gene1213	2.301e-62	222.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,1KRSM@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_5847521_2	257313.BP2291	6.823e-154	498.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VJ9X@28216|Betaproteobacteria,3T1KF@506|Alcaligenaceae	28216|Betaproteobacteria	CE	Tartrate dehydrogenase	ttuC	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
CMS1_k127_5847521_10	929556.Solca_4105	1.502e-33	130.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IPCH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
CMS1_k127_5848069_3	717774.Marme_0378	4.947e-23	106.0	2DP4G@1|root,330H8@2|Bacteria,1NN5J@1224|Proteobacteria,1SECA@1236|Gammaproteobacteria,1XMQ7@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5848069_0	365046.Rta_17950	1.694e-136	466.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2VISJ@28216|Betaproteobacteria,4ABYT@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD binding domain	-	-	1.14.13.1,1.14.13.24	ko:K00480,ko:K22270	ko00362,ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00362,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R02589,R05632,R06915,R06936,R06939	RC00046,RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
CMS1_k127_5848069_1	795666.MW7_2535	3.124e-125	412.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VHZV@28216|Betaproteobacteria,1KGJP@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dehydrogenase	-	-	1.1.99.31	ko:K15054	ko00627,ko01120,map00627,map01120	-	R04160,R07664	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
CMS1_k127_5848069_2	1121920.AUAU01000005_gene1045	3.261e-125	408.0	COG0329@1|root,COG0329@2|Bacteria,3Y8R8@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_5855000_13	395493.BegalDRAFT_0647	6.811e-112	364.0	COG0464@1|root,COG0464@2|Bacteria,1MUCN@1224|Proteobacteria,1RQPB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM AAA ATPase central domain protein	-	-	-	ko:K06413	-	-	-	-	ko00000	-	-	-	AAA
CMS1_k127_5855000_22	1122604.JONR01000027_gene3082	2.354e-69	237.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S23R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
CMS1_k127_5855000_1	991905.SL003B_0988	4.541e-275	850.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2TSJV@28211|Alphaproteobacteria,4BSN9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Ribulose bisphosphate carboxylase large chain, catalytic domain	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
CMS1_k127_5855000_16	381666.H16_B1705	9.852e-98	329.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,1JZPR@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5855000_20	748247.AZKH_2167	4.756e-81	293.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2VQIR@28216|Betaproteobacteria,2KW28@206389|Rhodocyclales	206389|Rhodocyclales	L	NADH pyrophosphatase-like rudimentary NUDIX domain	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
CMS1_k127_5855000_12	76114.ebA2152	3.557e-128	422.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,1MVV5@1224|Proteobacteria,2WGFP@28216|Betaproteobacteria,2KUTH@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS1_k127_5855000_4	1265502.KB905930_gene1543	5.519e-197	647.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,4AAEX@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_5855000_6	596154.Alide2_4702	1.626e-166	533.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2VHQ8@28216|Betaproteobacteria,4AAK9@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM amidase, hydantoinase carbamoylase family	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_5855000_19	159087.Daro_0675	3.167e-85	304.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV5K@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
CMS1_k127_5855000_11	365046.Rta_09050	1.545e-129	418.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,4AA1T@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS1_k127_5855000_17	331869.BAL199_19908	2.969e-92	327.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,2TQJ6@28211|Alphaproteobacteria,4BPVS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_27190	-	1.1.1.30	ko:K00019,ko:K18335	ko00051,ko00072,ko00650,ko01100,ko01120,map00051,map00072,map00650,map01100,map01120	M00088	R01361,R10690	RC00089,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS1_k127_5855000_24	864073.HFRIS_008006	6.57e-61	218.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2VP3Y@28216|Betaproteobacteria,478NQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_5855000_10	1411123.JQNH01000001_gene143	9.422e-145	466.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	MA20_27205	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
CMS1_k127_5855000_3	1095769.CAHF01000007_gene1661	1.346e-202	657.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2VJYY@28216|Betaproteobacteria	28216|Betaproteobacteria	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5855000_7	1095769.CAHF01000007_gene1660	1.737e-161	512.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2VHA0@28216|Betaproteobacteria,477H5@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type sugar	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
CMS1_k127_5855000_8	1144342.PMI40_00589	4.325e-156	497.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2VNEK@28216|Betaproteobacteria,477GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5855000_15	1040989.AWZU01000030_gene817	8.359e-99	342.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,3JT3N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_27185	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
CMS1_k127_5855000_0	1211115.ALIQ01000206_gene4728	1.099e-310	970.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,3NC3N@45404|Beijerinckiaceae	28211|Alphaproteobacteria	EG	Dehydratase family	ilvD2	-	4.2.1.25	ko:K13875	ko00053,ko01100,map00053,map01100	-	R02522	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
CMS1_k127_5855000_14	1207063.P24_02906	1.252e-110	385.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,2TTQ8@28211|Alphaproteobacteria,2JRAH@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_5855000_25	864051.BurJ1DRAFT_3903	3.374e-58	208.0	COG3090@1|root,COG3090@2|Bacteria,1R7TV@1224|Proteobacteria,2VPJP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_5855000_5	365046.Rta_08990	4.976e-191	612.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,4AA1X@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_5855000_9	1121106.JQKB01000001_gene3136	1.305e-149	480.0	COG1995@1|root,COG3395@1|root,COG1995@2|Bacteria,COG3395@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2JRWE@204441|Rhodospirillales	204441|Rhodospirillales	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
CMS1_k127_5855000_2	1123504.JQKD01000002_gene3737	2.002e-220	696.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria,4AB17@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	uxaA	-	4.2.1.7,4.4.1.24	ko:K01685,ko:K16846	ko00040,ko00270,ko01100,map00040,map00270,map01100	M00631	R01540,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
CMS1_k127_5855000_21	1408254.T458_26085	6.582e-78	280.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,4HGQE@91061|Bacilli,275PT@186822|Paenibacillaceae	91061|Bacilli	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_5855000_18	76114.ebA1095	2.159e-90	300.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,2KW4T@206389|Rhodocyclales	206389|Rhodocyclales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_5855000_23	292415.Tbd_0155	1.378e-63	226.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,1KSFC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA methyltransferase	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_5864857_20	589865.DaAHT2_2409	1.162e-20	96.0	COG1216@1|root,COG1216@2|Bacteria,1R13V@1224|Proteobacteria,43D64@68525|delta/epsilon subdivisions,2X8CV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5864857_8	589865.DaAHT2_2410	2.013e-101	349.0	COG0535@1|root,COG0535@2|Bacteria,1RADC@1224|Proteobacteria,42RDA@68525|delta/epsilon subdivisions,2WN4I@28221|Deltaproteobacteria,2MM5N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
CMS1_k127_5864857_3	589865.DaAHT2_2411	8.2e-175	592.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MI4U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_5864857_9	1487953.JMKF01000005_gene598	2.231e-88	309.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS1_k127_5864857_29	690850.Desaf_1963	8.125e-05	51.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2MBG2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Universal stress protein	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
CMS1_k127_5864857_16	713586.KB900536_gene2194	2.863e-28	115.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	yedF	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0033554,GO:0042592,GO:0048878,GO:0050896,GO:0051716,GO:0055082,GO:0065007,GO:0065008	-	-	-	-	-	-	-	-	-	-	TusA
CMS1_k127_5864857_4	396588.Tgr7_0063	9.023e-151	490.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1SH3M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_5864857_25	644282.Deba_2368	3.134e-08	60.0	2DP9Z@1|root,3316S@2|Bacteria,1R1CI@1224|Proteobacteria,42V8N@68525|delta/epsilon subdivisions,2X8FK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5864857_21	330214.NIDE3836	2.659e-19	97.0	COG2197@1|root,COG3290@1|root,COG2197@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	prhJ	-	-	ko:K06375	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	GerE,HATPase_c,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_5864857_13	570967.JMLV01000007_gene913	1.066e-42	161.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2UC0B@28211|Alphaproteobacteria,2JT9C@204441|Rhodospirillales	204441|Rhodospirillales	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
CMS1_k127_5864857_24	435591.BDI_3746	1.47e-08	63.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,2FSBR@200643|Bacteroidia,22YJ9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS1_k127_5864857_14	593750.Metfor_2443	4.817e-38	159.0	COG0785@1|root,arCOG02400@2157|Archaea,2Y0J2@28890|Euryarchaeota,2NBK2@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
CMS1_k127_5864857_23	768706.Desor_0537	1.424e-11	68.0	COG3462@1|root,COG3462@2|Bacteria,1VKBD@1239|Firmicutes,24UGB@186801|Clostridia,263B0@186807|Peptococcaceae	186801|Clostridia	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS1_k127_5864857_28	1049564.TevJSym_ap00160	1.609e-05	56.0	2DTMP@1|root,33KXW@2|Bacteria,1QTDR@1224|Proteobacteria,1SVC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
CMS1_k127_5864857_17	1163617.SCD_n00747	4.37e-27	117.0	2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,2VVCA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5864857_12	76114.ebA177	1.262e-44	175.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria,2KWFR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5864857_19	1294143.H681_04940	5.354e-22	104.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CMS1_k127_5864857_1	1209989.TepiRe1_1537	2.454e-299	947.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,42EJU@68295|Thermoanaerobacterales	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
CMS1_k127_5864857_6	224324.aq_1226	1.334e-132	435.0	COG1812@1|root,COG1812@2|Bacteria,2G3UM@200783|Aquificae	200783|Aquificae	E	PFAM S-adenosylmethionine synthetase (MAT)	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
CMS1_k127_5864857_2	404589.Anae109_4120	1.119e-181	577.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2Z0MS@29|Myxococcales	28221|Deltaproteobacteria	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_5864857_22	690850.Desaf_1137	1.626e-17	92.0	2E9MH@1|root,333U5@2|Bacteria,1NDRZ@1224|Proteobacteria,42VYW@68525|delta/epsilon subdivisions,2WR91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5864857_18	1255043.TVNIR_1504	4.356e-25	119.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,1SAW8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	dksA traR	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_5864857_11	1123392.AQWL01000003_gene118	3.039e-75	261.0	COG2823@1|root,COG2823@2|Bacteria,1RFX5@1224|Proteobacteria,2VRR5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BON domain	osmY	-	-	-	-	-	-	-	-	-	-	-	BON
CMS1_k127_5864857_7	697282.Mettu_0390	2e-101	339.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,1S0QR@1236|Gammaproteobacteria,1XFU4@135618|Methylococcales	135618|Methylococcales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS1_k127_5864857_0	279714.FuraDRAFT_2622	4.946e-307	951.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KPV9@206351|Neisseriales	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_5864857_5	748247.AZKH_1502	8.981e-137	443.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_5864857_26	743721.Psesu_2576	4.095e-08	58.0	2ADXY@1|root,313Q5@2|Bacteria,1QD3E@1224|Proteobacteria,1T8YQ@1236|Gammaproteobacteria,1XBEN@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5864857_27	261292.Nit79A3_2268	7.423e-07	60.0	COG4782@1|root,COG4782@2|Bacteria,1N9HN@1224|Proteobacteria	1224|Proteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
CMS1_k127_5864857_15	102129.Lepto7375DRAFT_0197	4.225e-35	139.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5867480_4	640081.Dsui_0154	2.818e-45	174.0	COG4944@1|root,COG4944@2|Bacteria,1MXEV@1224|Proteobacteria,2VRI6@28216|Betaproteobacteria,2KX91@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
CMS1_k127_5867480_2	159087.Daro_2590	4.359e-78	265.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2VRBF@28216|Betaproteobacteria,2KYA9@206389|Rhodocyclales	206389|Rhodocyclales	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5867480_3	29581.BW37_04311	2.731e-67	239.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2W04J@28216|Betaproteobacteria,477AS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
CMS1_k127_5867480_1	477184.KYC_11723	4.91e-90	300.0	COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2VJ2X@28216|Betaproteobacteria,3T5JG@506|Alcaligenaceae	28216|Betaproteobacteria	C	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_5867480_0	159087.Daro_2592	3.743e-149	473.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VJSK@28216|Betaproteobacteria,2KVXW@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS1_k127_5867480_6	296591.Bpro_0540	4.34e-16	81.0	2DQ9K@1|root,335GG@2|Bacteria,1NAA4@1224|Proteobacteria,2VW5N@28216|Betaproteobacteria,4AFQ9@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM pentapeptide MXKDX repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5867480_5	266265.Bxe_B1517	1.088e-44	164.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,1K5EP@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
CMS1_k127_5868184_1	1304883.KI912532_gene984	4.002e-147	475.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,2KVG7@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_5868184_4	1000565.METUNv1_03399	1.61e-89	314.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,2KVAA@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS1_k127_5868184_5	640081.Dsui_0477	4.452e-56	205.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,2KW31@206389|Rhodocyclales	206389|Rhodocyclales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TolA_bind_tri
CMS1_k127_5868184_7	1000565.METUNv1_03397	7.48e-43	174.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,2KWKV@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS1_k127_5868184_0	76114.ebA2650	3.917e-174	563.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KUUQ@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_5868184_6	159087.Daro_4054	7.037e-47	182.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,2VKUS@28216|Betaproteobacteria,2KVZ9@206389|Rhodocyclales	206389|Rhodocyclales	M	TonB C terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
CMS1_k127_5868184_8	1266925.JHVX01000011_gene1493	1.739e-33	134.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,3737B@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
CMS1_k127_5868184_2	1454004.AW11_02784	2.096e-101	336.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,1KQ2W@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Mota tolq exbb proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
CMS1_k127_5868184_9	1097668.BYI23_A021730	2.184e-31	127.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,1K7NF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
CMS1_k127_5868184_3	582744.Msip34_2404	3.551e-96	318.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,2KKIG@206350|Nitrosomonadales	206350|Nitrosomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_5873332_6	631454.N177_1057	6.283e-140	469.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TQVT@28211|Alphaproteobacteria,1JNU5@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_5873332_8	485918.Cpin_2522	8.647e-117	383.0	COG0500@1|root,COG2226@2|Bacteria,4NFRD@976|Bacteroidetes,1IVKT@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_5873332_12	631454.N177_0649	1.338e-43	182.0	COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,2U6GE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_5873332_0	631454.N177_0648	1.156e-308	984.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5873332_3	991905.SL003B_2525	1.221e-199	646.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2TSRQ@28211|Alphaproteobacteria,4BRHP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
CMS1_k127_5873332_2	1207063.P24_13673	3.185e-248	775.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JQSB@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
CMS1_k127_5873332_9	1298867.AUES01000017_gene3997	3.309e-98	330.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,3JTIU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_5873332_10	113395.AXAI01000014_gene261	1.665e-97	323.0	COG1028@1|root,COG1028@2|Bacteria,1RBGC@1224|Proteobacteria,2U6FD@28211|Alphaproteobacteria,3JXHW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5873332_11	1380394.JADL01000001_gene3032	7.382e-61	217.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,2JSRE@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
CMS1_k127_5873332_7	991905.SL003B_2528	2.855e-138	451.0	COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,2TRA1@28211|Alphaproteobacteria,4BQH8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K13794,ko:K19338	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5873332_4	1298867.AUES01000017_gene3998	2.265e-198	627.0	COG0683@1|root,COG0683@2|Bacteria,1N11P@1224|Proteobacteria,2TRQ4@28211|Alphaproteobacteria,3JVI6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_5873332_5	991905.SL003B_2530	1.278e-145	465.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2U0TW@28211|Alphaproteobacteria,4BQG1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_5873332_1	991905.SL003B_2531	4.112e-272	863.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
CMS1_k127_588627_9	698761.RTCIAT899_CH13040	2.548e-39	148.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,4B7KK@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_588627_10	1485544.JQKP01000002_gene1417	9.437e-13	82.0	COG4190@1|root,COG4190@2|Bacteria,1N98Y@1224|Proteobacteria,2VXMQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_588627_11	1532558.JL39_28290	2.522e-08	59.0	2E33J@1|root,32Y3P@2|Bacteria,1N9JJ@1224|Proteobacteria,2V6FG@28211|Alphaproteobacteria,4BGRF@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_588627_0	472759.Nhal_0770	9.288e-288	897.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1WWS1@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_588627_5	1449353.JQMQ01000004_gene5932	3.191e-107	364.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,2NHIR@228398|Streptacidiphilus	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_588627_2	1380394.JADL01000002_gene1394	2.512e-211	666.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,2JT4J@204441|Rhodospirillales	204441|Rhodospirillales	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CMS1_k127_588627_1	450851.PHZ_p0070	7.798e-287	902.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,2KFS4@204458|Caulobacterales	28211|Alphaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_588627_8	94624.Bpet3853	2.474e-39	151.0	COG0071@1|root,COG0071@2|Bacteria,1N0RH@1224|Proteobacteria,2VVUG@28216|Betaproteobacteria,3T88F@506|Alcaligenaceae	28216|Betaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS1_k127_588627_7	292415.Tbd_2635	3.482e-49	179.0	COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria,2W3WC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_588627_4	1163617.SCD_n02290	4.79e-121	417.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
CMS1_k127_588627_3	243233.MCA2512	2.158e-196	637.0	COG3511@1|root,COG3511@2|Bacteria,1MVNS@1224|Proteobacteria,1RZUB@1236|Gammaproteobacteria,1XDZS@135618|Methylococcales	135618|Methylococcales	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
CMS1_k127_588627_6	497321.C664_10662	1.762e-70	247.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,2KXUE@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
CMS1_k127_5897101_0	1380355.JNIJ01000033_gene4280	1.142e-148	477.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,3JSUM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	MA20_15910	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_5897101_1	1394178.AWOO02000009_gene4357	3.649e-136	456.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_5898330_5	296591.Bpro_4514	2.003e-38	144.0	COG0119@1|root,COG1804@1|root,COG0119@2|Bacteria,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2VJB6@28216|Betaproteobacteria,4AAJC@80864|Comamonadaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3,HMGL-like
CMS1_k127_5898330_1	1121861.KB899919_gene2714	6.943e-160	516.0	COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2TRIZ@28211|Alphaproteobacteria,2JQ9Z@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3,HMGL-like
CMS1_k127_5898330_3	335283.Neut_1063	5.748e-51	184.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria,373HM@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5898330_4	1192868.CAIU01000008_gene1179	1.242e-40	152.0	COG1917@1|root,COG1917@2|Bacteria,1N7QJ@1224|Proteobacteria,2UFRZ@28211|Alphaproteobacteria,43KC6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	MA20_03790	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	Cupin_2
CMS1_k127_5898330_6	397945.Aave_3315	8.951e-37	146.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2VRBU@28216|Betaproteobacteria,4AE3V@80864|Comamonadaceae	28216|Betaproteobacteria	S	Haem-degrading	glcG	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
CMS1_k127_5898330_0	76114.ebA7220	4.466e-302	936.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VI3T@28216|Betaproteobacteria,2KV9F@206389|Rhodocyclales	206389|Rhodocyclales	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_5898330_2	159087.Daro_1202	1.365e-107	353.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,2KU9K@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_598932_6	1110502.TMO_1956	4.834e-112	376.0	COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria,2TUBJ@28211|Alphaproteobacteria,2JPTM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_598932_7	488538.SAR116_1471	2.785e-83	289.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
CMS1_k127_598932_0	1238182.C882_3364	1.708e-268	840.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,2JQKH@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
CMS1_k127_598932_4	631454.N177_4103	6.393e-130	423.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2UEZT@28211|Alphaproteobacteria,1JPP3@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
CMS1_k127_598932_5	1000565.METUNv1_04051	1.001e-120	393.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,2KV23@206389|Rhodocyclales	206389|Rhodocyclales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS1_k127_598932_2	62928.azo1607	1.812e-156	501.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CMS1_k127_598932_8	420662.Mpe_A1164	1.841e-35	141.0	2DBXD@1|root,2ZBP6@2|Bacteria,1RB44@1224|Proteobacteria,2VQT3@28216|Betaproteobacteria,1KKYG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
CMS1_k127_598932_10	402626.Rpic_2590	1.994e-16	91.0	2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,1K8AT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3306
CMS1_k127_598932_1	1000565.METUNv1_04055	1.72e-237	753.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,2KVUW@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
CMS1_k127_598932_9	543728.Vapar_4064	6.558e-30	134.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,4ACXM@80864|Comamonadaceae	28216|Betaproteobacteria	S	cytoplasmic chaperone TorD family protein	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
CMS1_k127_598932_11	497321.C664_18539	0.0002575	49.0	2ENJT@1|root,33G76@2|Bacteria,1NMX3@1224|Proteobacteria,2VXMJ@28216|Betaproteobacteria,2KXNQ@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_598932_3	314231.FP2506_17949	2.923e-148	478.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_5990278_30	62928.azo3483	2.735e-05	50.0	2ENJT@1|root,33G76@2|Bacteria,1NMX3@1224|Proteobacteria,2VXMJ@28216|Betaproteobacteria,2KXNQ@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5990278_0	204773.HEAR1412	0.0	1487.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,472J6@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_5990278_7	375286.mma_1969	4.675e-123	395.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,4739G@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	fdhB	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_7
CMS1_k127_5990278_29	1000565.METUNv1_04060	3.597e-09	65.0	2E8DM@1|root,332S3@2|Bacteria,1ND1I@1224|Proteobacteria,2VX0K@28216|Betaproteobacteria,2KX9Z@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5990278_10	388051.AUFE01000008_gene1699	1.09e-107	363.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,1K1V2@119060|Burkholderiaceae	28216|Betaproteobacteria	C	formate dehydrogenase	fdhC	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
CMS1_k127_5990278_5	543728.Vapar_5759	6.876e-179	576.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,4AABT@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CMS1_k127_5990278_13	1380355.JNIJ01000040_gene5195	2.75e-88	302.0	COG0607@1|root,COG4275@1|root,COG0607@2|Bacteria,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TRC3@28211|Alphaproteobacteria,3JRCM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist,Rhodanese
CMS1_k127_5990278_14	272630.MexAM1_META1p4216	7.288e-87	303.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2TV55@28211|Alphaproteobacteria,1JSIV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	HP	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS1_k127_5990278_9	272630.MexAM1_META1p4215	3.318e-118	400.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,1JSUQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_5990278_8	1207063.P24_17082	4.417e-119	400.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,2JQNZ@204441|Rhodospirillales	204441|Rhodospirillales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
CMS1_k127_5990278_15	1298858.AUEL01000016_gene2512	6.757e-85	286.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria,43IV3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Molybdate ABC transporter	modB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS1_k127_5990278_18	414684.RC1_2219	2.822e-71	256.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,2JRR1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS1_k127_5990278_20	1122603.ATVI01000005_gene2998	1.414e-64	234.0	COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,1RS4Y@1236|Gammaproteobacteria,1X5R1@135614|Xanthomonadales	135614|Xanthomonadales	P	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,PBP_like
CMS1_k127_5990278_12	1000565.METUNv1_01234	6.348e-91	305.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2VNEC@28216|Betaproteobacteria,2KVSG@206389|Rhodocyclales	206389|Rhodocyclales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
CMS1_k127_5990278_17	1244869.H261_13154	1.737e-77	277.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,2JRVW@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_5990278_11	1411123.JQNH01000001_gene584	4.51e-106	357.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2TU33@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG2998 ABC-type tungstate transport system, permease component	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
CMS1_k127_5990278_21	1000565.METUNv1_02803	5.522e-64	224.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,2KWDE@206389|Rhodocyclales	206389|Rhodocyclales	H	molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
CMS1_k127_5990278_6	1095769.CAHF01000010_gene1265	7.273e-154	519.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,472MS@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Probable molybdopterin binding domain	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_5990278_25	85643.Tmz1t_2524	5.479e-25	109.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,2KX9K@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_5990278_19	1454004.AW11_00359	6.998e-66	228.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1KQQA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
CMS1_k127_5990278_22	1485544.JQKP01000019_gene24	2.924e-42	162.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,44VTA@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS1_k127_5990278_24	1192124.LIG30_3577	1.006e-27	115.0	COG1993@1|root,COG1993@2|Bacteria,1N2YV@1224|Proteobacteria,2VWYD@28216|Betaproteobacteria,1K8G5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
CMS1_k127_5990278_3	935840.JAEQ01000010_gene1491	1.501e-259	814.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,43GXZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_5990278_1	1288494.EBAPG3_24770	0.0	1341.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,371VX@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_5990278_28	469371.Tbis_0924	2.981e-16	88.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4DZ3Q@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS1_k127_5990278_26	1121920.AUAU01000004_gene767	1.795e-20	102.0	COG1678@1|root,COG1678@2|Bacteria,3Y8TX@57723|Acidobacteria	57723|Acidobacteria	K	Uncharacterized ACR, COG1678	-	-	-	-	-	-	-	-	-	-	-	-	DUF179
CMS1_k127_5990278_23	580332.Slit_1116	3.201e-35	144.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	CRP FNR family	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5990278_27	1121405.dsmv_2550	5.727e-20	93.0	COG4770@1|root,COG4770@2|Bacteria,1NCKN@1224|Proteobacteria,42W8Y@68525|delta/epsilon subdivisions,2WRW7@28221|Deltaproteobacteria,2MM43@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
CMS1_k127_5990278_4	1125863.JAFN01000001_gene3100	4.813e-179	567.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5990278_2	1187851.A33M_2769	8.415e-290	900.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria	1224|Proteobacteria	I	PFAM carboxyl transferase	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
CMS1_k127_5990278_16	1123368.AUIS01000031_gene1427	1.022e-81	279.0	COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,1RRV8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	CLP1_P,Lactamase_B,Lactamase_B_2
CMS1_k127_6012840_9	266265.Bxe_A4084	2.654e-08	56.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VMYW@28216|Betaproteobacteria,1K1RG@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_6012840_5	1458275.AZ34_12785	1.44e-90	308.0	2A8H0@1|root,30XJ2@2|Bacteria,1REE0@1224|Proteobacteria,2W21U@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6012840_7	203122.Sde_0123	6.36e-24	113.0	COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,1S9RI@1236|Gammaproteobacteria,467ZM@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3764 Sortase (surface protein transpeptidase)	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS1_k127_6012840_4	1120970.AUBZ01000007_gene3003	1.935e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,465DT@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	chvI	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K02483,ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_6012840_2	722419.PH505_bv00110	4.673e-113	384.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,2Q0GF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS1_k127_6012840_1	1217720.ALOX01000001_gene3399	1.32e-172	556.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,2JQAF@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS1_k127_6012840_3	1121406.JAEX01000002_gene769	1.252e-93	320.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,42P98@68525|delta/epsilon subdivisions,2WJWW@28221|Deltaproteobacteria,2MA81@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS1_k127_6012840_6	1266925.JHVX01000003_gene519	6.495e-83	295.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,372PK@32003|Nitrosomonadales	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
CMS1_k127_6012840_0	1095769.CAHF01000013_gene3211	1.141e-202	649.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIJX@28216|Betaproteobacteria,475ME@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	matB	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_6012840_8	641524.ADICYQ_5472	4.321e-12	70.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_6034346_24	76114.ebA2896	2.966e-24	115.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV1U@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,Protoglobin
CMS1_k127_6034346_11	1316936.K678_04231	3.827e-85	301.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,2JQ6B@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_6034346_9	1150626.PHAMO_270063	1.45e-97	326.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,2JR23@204441|Rhodospirillales	204441|Rhodospirillales	E	branched-chain amino acid transport	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
CMS1_k127_6034346_6	1121033.AUCF01000014_gene1265	8.268e-124	404.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,2JPIB@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_6034346_7	1244869.H261_15507	2.176e-115	381.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,2JPSA@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_6034346_3	1120983.KB894570_gene1258	1.874e-161	516.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2TU0F@28211|Alphaproteobacteria,1JPS1@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_6034346_18	1150469.RSPPHO_01830	7.329e-43	169.0	COG1959@1|root,COG1959@2|Bacteria,1PZ79@1224|Proteobacteria,2UCUA@28211|Alphaproteobacteria,2JTF5@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_6034346_2	1411123.JQNH01000001_gene2516	4.093e-207	661.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytoene dehydrogenase	MA20_01895	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS1_k127_6034346_30	1504981.KO116_4759	2.33e-15	77.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SZ7I@1236|Gammaproteobacteria,1XRME@135619|Oceanospirillales	135619|Oceanospirillales	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_6034346_15	1207063.P24_00920	7.365e-73	257.0	COG1024@1|root,COG1024@2|Bacteria,1PU1Q@1224|Proteobacteria,2TSW6@28211|Alphaproteobacteria,2JS2P@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_6034346_5	1095769.CAHF01000022_gene145	5.036e-135	447.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,2VIIW@28216|Betaproteobacteria,473BE@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	copB	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_6034346_1	402626.Rpic_3912	1.971e-234	737.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VM67@28216|Betaproteobacteria,1K0ID@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	multicopper oxidase type 3	copA_2	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_6034346_20	1007105.PT7_1805	1.69e-39	164.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSS8@28216|Betaproteobacteria,3T491@506|Alcaligenaceae	28216|Betaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
CMS1_k127_6034346_25	365044.Pnap_4550	4.1e-23	105.0	COG5569@1|root,COG5569@2|Bacteria,1N8CJ@1224|Proteobacteria,2VVSU@28216|Betaproteobacteria,4AFJQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Copper binding periplasmic protein CusF	cusF	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
CMS1_k127_6034346_23	580332.Slit_2175	2.816e-25	115.0	COG3678@1|root,COG3678@2|Bacteria,1N2D7@1224|Proteobacteria,2VU8P@28216|Betaproteobacteria	28216|Betaproteobacteria	NPTU	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
CMS1_k127_6034346_28	472759.Nhal_1702	1.88e-17	84.0	COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,1TKC3@1236|Gammaproteobacteria,1X1RM@135613|Chromatiales	135613|Chromatiales	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS1_k127_6034346_17	395494.Galf_2722	1.513e-48	178.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6034346_26	365044.Pnap_1257	2.554e-22	108.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6034346_31	1499967.BAYZ01000060_gene5988	1.138e-12	70.0	2EQK7@1|root,33I68@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6034346_13	571166.KI421509_gene3765	3.428e-76	272.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS1_k127_6034346_14	1297569.MESS2_730262	4.969e-75	265.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,43H32@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CO	periplasmic protein thiol disulfide	cycY	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_6034346_16	1005048.CFU_2963	2.485e-52	191.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VSD1@28216|Betaproteobacteria,474HS@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	cueR	-	-	ko:K19591,ko:K19592	-	M00768,M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS1_k127_6034346_0	381666.H16_A3668	9.448e-301	943.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1K311@119060|Burkholderiaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_6034346_29	420662.Mpe_A3536	1.155e-15	79.0	COG2608@1|root,COG2608@2|Bacteria,1PUDM@1224|Proteobacteria,2VX77@28216|Betaproteobacteria,1KMS1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
CMS1_k127_6034346_27	535289.Dtpsy_2194	7.597e-18	86.0	2DVDD@1|root,32UZ7@2|Bacteria,1NGRW@1224|Proteobacteria,2VY85@28216|Betaproteobacteria,4AI78@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
CMS1_k127_6034346_32	472759.Nhal_3157	3.739e-08	59.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1WXRD@135613|Chromatiales	135613|Chromatiales	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
CMS1_k127_6034346_21	365044.Pnap_1257	2.639e-33	133.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6034346_10	1121918.ARWE01000001_gene3299	3.037e-91	306.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
CMS1_k127_6034346_12	1384056.N787_01670	5.926e-78	288.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,1X7D8@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
CMS1_k127_6034346_8	1384056.N787_01665	3.559e-107	364.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1X64I@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
CMS1_k127_6034346_4	338966.Ppro_2905	1.513e-140	474.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,43BJ5@68525|delta/epsilon subdivisions,2X713@28221|Deltaproteobacteria,43T59@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_tran
CMS1_k127_6034346_19	330214.NIDE0031	1.212e-41	170.0	COG1566@1|root,COG1566@2|Bacteria,3J0TB@40117|Nitrospirae	40117|Nitrospirae	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS1_k127_6122766_1	667632.KB890217_gene4927	6.142e-160	509.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1K2NF@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS1_k127_6122766_0	391735.Veis_4539	2.568e-217	683.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHZI@28216|Betaproteobacteria,4AC4M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
CMS1_k127_6122766_4	543728.Vapar_2222	1.248e-44	168.0	2E6D9@1|root,3310W@2|Bacteria,1N9Y9@1224|Proteobacteria,2VWRF@28216|Betaproteobacteria,4AHXJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
CMS1_k127_6122766_2	543728.Vapar_2221	1.522e-135	440.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VN5P@28216|Betaproteobacteria,4AGSI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_6122766_3	1123020.AUIE01000006_gene4198	3.313e-49	181.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1YE6K@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase,Aminotran_1_2,NAD_binding_4,PP-binding,Thioesterase
CMS1_k127_6147294_0	1454004.AW11_03482	3.422e-233	740.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_6147294_4	1532557.JL37_16165	1.833e-23	105.0	COG2050@1|root,COG2050@2|Bacteria,1RGQ6@1224|Proteobacteria,2VS7Y@28216|Betaproteobacteria,3T4KT@506|Alcaligenaceae	28216|Betaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_6147294_3	709986.Deima_1217	7.93e-99	329.0	COG1028@1|root,COG1028@2|Bacteria,1WIPQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
CMS1_k127_6147294_2	1040989.AWZU01000028_gene3006	9.617e-213	683.0	COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria,2TVKJ@28211|Alphaproteobacteria,3JSJV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	FAD binding domain	MA20_22130	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
CMS1_k127_6147294_1	338969.Rfer_3509	1.191e-225	714.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,4AAYC@80864|Comamonadaceae	28216|Betaproteobacteria	H	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_6147294_5	1415779.JOMH01000001_gene1762	2.526e-11	64.0	COG0388@1|root,COG3153@1|root,COG0388@2|Bacteria,COG3153@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1X55P@135614|Xanthomonadales	135614|Xanthomonadales	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS1_k127_6152486_3	640511.BC1002_2597	6.596e-131	423.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,1K092@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_6152486_12	1000565.METUNv1_02101	9.115e-14	76.0	2AF5U@1|root,3154P@2|Bacteria,1PV4V@1224|Proteobacteria,2WB3A@28216|Betaproteobacteria,2KXID@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6152486_2	595537.Varpa_5193	3.587e-135	439.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,4ACG6@80864|Comamonadaceae	28216|Betaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_6152486_6	1131553.JIBI01000002_gene1798	3.95e-106	370.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,372D2@32003|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiF	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
CMS1_k127_6152486_10	1458357.BG58_38220	1.597e-55	204.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,1K1N6@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
CMS1_k127_6152486_4	1163617.SCD_n02537	5.754e-126	417.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
CMS1_k127_6152486_8	159087.Daro_3485	3.782e-66	232.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VRUU@28216|Betaproteobacteria,2KWI9@206389|Rhodocyclales	206389|Rhodocyclales	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS1_k127_6152486_11	323848.Nmul_A2372	3.626e-52	189.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,37388@32003|Nitrosomonadales	28216|Betaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS1_k127_6152486_5	1144342.PMI40_04498	2.455e-108	354.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,472Z4@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_6152486_9	1532557.JL37_03710	1.819e-64	231.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,3T3KD@506|Alcaligenaceae	28216|Betaproteobacteria	G	Phosphoglycolate phosphatase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_6152486_0	1266925.JHVX01000010_gene1338	3e-185	591.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,372HF@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_6152486_7	335283.Neut_0135	5.084e-81	286.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,371WE@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Glutamine amidotransferase class-I	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_6152486_1	420662.Mpe_A3461	2.701e-135	446.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KJ9I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS1_k127_6185227_11	323848.Nmul_A2692	2.127e-93	310.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,371SR@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_6185227_5	305700.B447_08089	2.366e-144	464.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,2KUF6@206389|Rhodocyclales	206389|Rhodocyclales	T	phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS1_k127_6185227_19	76114.ebA1336	1.158e-41	160.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,2KWFT@206389|Rhodocyclales	206389|Rhodocyclales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS1_k127_6185227_10	85643.Tmz1t_0868	8.758e-121	393.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,2KV4Z@206389|Rhodocyclales	206389|Rhodocyclales	P	Mg2 and Co2 transporter CorC	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
CMS1_k127_6185227_6	1163617.SCD_n02571	9.414e-142	466.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS1_k127_6185227_4	887898.HMPREF0551_0153	6.317e-156	507.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,1K1XK@119060|Burkholderiaceae	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
CMS1_k127_6185227_1	76114.ebA1330	1.966e-212	693.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,2KUWE@206389|Rhodocyclales	206389|Rhodocyclales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS1_k127_6185227_14	395494.Galf_2099	7.317e-74	252.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,44VFT@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Polynucleotide kinase 3 phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_like,PNK3P
CMS1_k127_6185227_13	582744.Msip34_2129	1.002e-84	295.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,2KKR3@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_6185227_18	748247.AZKH_3566	4.816e-46	184.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,2KWES@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CMS1_k127_6185227_17	305700.B447_16507	3.471e-62	216.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,2KWC1@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS1_k127_6185227_12	748280.NH8B_4014	4.492e-85	289.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,2KPK9@206351|Neisseriales	206351|Neisseriales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_6185227_7	1163617.SCD_n02560	5.304e-140	458.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
CMS1_k127_6185227_3	640081.Dsui_1587	6.874e-169	557.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,2KVBE@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
CMS1_k127_6185227_8	93220.LV28_10955	1.044e-138	447.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,1K0G3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
CMS1_k127_6185227_16	76114.ebA1143	3.964e-67	242.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,2KV5Z@206389|Rhodocyclales	206389|Rhodocyclales	JM	Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CMS1_k127_6185227_21	396588.Tgr7_0561	2.822e-18	94.0	2CH9Q@1|root,344Q6@2|Bacteria,1P007@1224|Proteobacteria,1SS1R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6185227_2	1266925.JHVX01000008_gene274	3.687e-182	584.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,372V1@32003|Nitrosomonadales	28216|Betaproteobacteria	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS1_k127_6185227_15	1454004.AW11_02058	5.655e-71	254.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,1KPZH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	CH	FAD binding domain	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS1_k127_6185227_9	557598.LHK_03206	1.93e-127	417.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,2KPEA@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_6185227_20	62928.azo2893	6.148e-24	103.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,2KX0P@206389|Rhodocyclales	206389|Rhodocyclales	KL	Belongs to the transcriptional regulatory Fis family	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
CMS1_k127_6185227_0	269482.Bcep1808_0656	4.099e-230	725.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,1K3VV@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_628924_0	1380394.JADL01000011_gene3905	7.076e-212	668.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_628924_23	56780.SYN_01324	3.921e-86	298.0	COG2199@1|root,COG3706@2|Bacteria,1RCC4@1224|Proteobacteria,43AED@68525|delta/epsilon subdivisions,2WQS7@28221|Deltaproteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_628924_9	1532557.JL37_29785	6.903e-127	412.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,3T1UG@506|Alcaligenaceae	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS1_k127_628924_31	398578.Daci_5624	3.518e-56	207.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,4AAQF@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_628924_21	338969.Rfer_0960	2.326e-88	312.0	COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_628924_41	1184267.A11Q_1612	3.929e-31	140.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,430NN@68525|delta/epsilon subdivisions,2MT6T@213481|Bdellovibrionales,2WVYS@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
CMS1_k127_628924_15	748247.AZKH_3944	2.714e-107	368.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria,2KVMB@206389|Rhodocyclales	206389|Rhodocyclales	S	Beta-lactamase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_628924_24	216591.BCAL2782	2.432e-81	276.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,1JZMU@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Hemerythrin,PNP_phzG_C,Putative_PNPOx
CMS1_k127_628924_14	1122132.AQYH01000004_gene1605	1.634e-109	374.0	COG4857@1|root,COG4857@2|Bacteria,1MXBW@1224|Proteobacteria,2TR0Z@28211|Alphaproteobacteria,4BD98@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_628924_5	1122132.AQYH01000004_gene1606	2.96e-152	504.0	COG0148@1|root,COG0148@2|Bacteria,1PIEJ@1224|Proteobacteria,2TT8V@28211|Alphaproteobacteria,4BD27@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_628924_28	1266925.JHVX01000004_gene1239	1e-68	240.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,2VIQD@28216|Betaproteobacteria,371Q9@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_628924_18	76114.ebA5309	1.855e-96	332.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2VHGT@28216|Betaproteobacteria,2KZYM@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_628924_20	365046.Rta_22380	5.37e-89	302.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2VKUM@28216|Betaproteobacteria,4ABGV@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_628924_19	85643.Tmz1t_3087	1.394e-91	323.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VK9Y@28216|Betaproteobacteria,2KV1M@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_628924_12	76114.ebA5304	3.845e-118	387.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,2KXZ1@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_628924_3	1244869.H261_06776	9.689e-162	520.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria,2JWU0@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_628924_10	1207063.P24_10011	3.281e-122	396.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria,2JRNC@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_628924_32	1254432.SCE1572_30125	1.128e-53	205.0	COG3437@1|root,COG3829@1|root,COG3852@1|root,COG4251@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CDW@68525|delta/epsilon subdivisions,2X7X2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS1_k127_628924_16	402626.Rpic_4715	1.836e-100	346.0	COG0491@1|root,COG0491@2|Bacteria,1MW35@1224|Proteobacteria,2VPNG@28216|Betaproteobacteria,1K5T5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_628924_22	987059.RBXJA2T_13009	1.036e-86	291.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,2VHDT@28216|Betaproteobacteria,1KN0J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	haloacid dehalogenase-like hydrolase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
CMS1_k127_628924_11	189753.AXAS01000047_gene108	1.476e-120	401.0	COG0654@1|root,COG0654@2|Bacteria,1QW6Y@1224|Proteobacteria,2TWQJ@28211|Alphaproteobacteria,3JS5Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,NAD_binding_8
CMS1_k127_628924_40	1123261.AXDW01000011_gene576	5.473e-36	145.0	28NH4@1|root,2ZBJ2@2|Bacteria,1N1V3@1224|Proteobacteria,1T0IS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_628924_26	29581.BW37_01988	1.403e-77	280.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,476NK@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	tsr	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH
CMS1_k127_628924_2	1268622.AVS7_00270	1.104e-172	578.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VNJN@28216|Betaproteobacteria,4ACBA@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
CMS1_k127_628924_1	1123023.JIAI01000024_gene4225	4.391e-191	610.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4E1U7@85010|Pseudonocardiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6,2.5.1.66	ko:K01652,ko:K12673	ko00290,ko00331,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00331,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570,M00674	R00006,R00014,R00226,R03050,R04672,R04673,R05465,R08648	RC00027,RC00106,RC00215,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_628924_43	264198.Reut_A0399	6.788e-17	89.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,2VW3E@28216|Betaproteobacteria,1K95B@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
CMS1_k127_628924_45	264198.Reut_A0400	1.988e-12	74.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQW@28216|Betaproteobacteria,1K9MD@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type 4 fimbrial pilin related transmembrane protein	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
CMS1_k127_628924_36	580332.Slit_2165	2.65e-44	168.0	COG4967@1|root,COG4967@2|Bacteria,1RK2M@1224|Proteobacteria,2VT1W@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
CMS1_k127_628924_30	1217718.ALOU01000031_gene1576	2.29e-57	213.0	COG4966@1|root,COG4966@2|Bacteria,1RC4Q@1224|Proteobacteria,2VS7N@28216|Betaproteobacteria,1K54M@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type 4 fimbrial biogenesis	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
CMS1_k127_628924_46	1123020.AUIE01000026_gene4844	3.607e-06	60.0	COG4726@1|root,COG4726@2|Bacteria,1N7I4@1224|Proteobacteria,1TC2X@1236|Gammaproteobacteria,1YJR4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_628924_8	1217718.ALOU01000031_gene1578	9.776e-130	467.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VJEX@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
CMS1_k127_628924_7	1380394.JADL01000004_gene5741	1.245e-142	456.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,2JQE0@204441|Rhodospirillales	204441|Rhodospirillales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CMS1_k127_628924_35	1415779.JOMH01000001_gene134	7.944e-45	167.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria,1X82P@135614|Xanthomonadales	135614|Xanthomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS1_k127_628924_13	1038859.AXAU01000001_gene3187	1.449e-111	375.0	COG0625@1|root,COG0625@2|Bacteria,1NE6Z@1224|Proteobacteria,2TVN6@28211|Alphaproteobacteria,3JVXF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_N
CMS1_k127_628924_37	402626.Rpic_4569	1.797e-43	169.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VTFT@28216|Betaproteobacteria,1KHAQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	3-Demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
CMS1_k127_628924_33	338969.Rfer_4025	1.503e-47	177.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VSH3@28216|Betaproteobacteria,4AEBC@80864|Comamonadaceae	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS1_k127_628924_17	1403819.BATR01000132_gene4687	1.916e-99	336.0	COG0262@1|root,COG0262@2|Bacteria,46SEV@74201|Verrucomicrobia	74201|Verrucomicrobia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS1_k127_628924_29	1116369.KB890024_gene2135	4.131e-60	212.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,43KH4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
CMS1_k127_628924_4	1535287.JP74_21635	1.376e-156	503.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2TSNH@28211|Alphaproteobacteria,3N6CQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_628924_25	1163398.AJJP01000043_gene2324	3.24e-81	278.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,1S31J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
CMS1_k127_628924_34	1278073.MYSTI_07011	2.543e-47	181.0	COG3832@1|root,COG3832@2|Bacteria,1RHJJ@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_628924_39	886293.Sinac_7081	1.099e-37	145.0	COG0640@1|root,COG0640@2|Bacteria,2J3R2@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS1_k127_628924_27	1123072.AUDH01000005_gene1540	1.113e-69	247.0	COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,2TVBS@28211|Alphaproteobacteria,2JTAE@204441|Rhodospirillales	204441|Rhodospirillales	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
CMS1_k127_628924_38	398525.KB900701_gene4747	7.174e-42	158.0	COG1846@1|root,COG1846@2|Bacteria,1RJ2M@1224|Proteobacteria,2U136@28211|Alphaproteobacteria,3JWAW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_628924_44	204669.Acid345_2641	7.282e-16	83.0	COG5485@1|root,COG5485@2|Bacteria,3Y5VH@57723|Acidobacteria,2JNTY@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_628924_42	994479.GL877878_gene80	1.043e-26	120.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4EE3P@85010|Pseudonocardiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_628924_6	991905.SL003B_1053	2.869e-145	470.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,4BR6A@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_64088_1	93220.LV28_08040	2.082e-201	631.0	COG0673@1|root,COG0673@2|Bacteria,1PYTN@1224|Proteobacteria,2VKKE@28216|Betaproteobacteria,1KGRJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_64088_9	1123504.JQKD01000005_gene4754	2.875e-74	256.0	COG1309@1|root,COG1309@2|Bacteria,1R5AI@1224|Proteobacteria,2VH3Y@28216|Betaproteobacteria,4ABHB@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_9,TetR_N
CMS1_k127_64088_6	224911.27352466	3.043e-109	374.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,3JR64@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	MA20_28765	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS1_k127_64088_8	335659.S23_40560	2.346e-94	318.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2U18X@28211|Alphaproteobacteria,3JTGT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	MA20_28785	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_64088_5	1231190.NA8A_19218	4.809e-116	383.0	COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2TSHF@28211|Alphaproteobacteria,43H6C@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	MA20_28795	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_64088_10	1121861.KB899924_gene3561	5.288e-63	228.0	COG0454@1|root,COG0456@2|Bacteria,1R28Z@1224|Proteobacteria,2TZDU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_64088_4	497964.CfE428DRAFT_3855	2.556e-129	425.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Cobalamin-independent synthase, Catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
CMS1_k127_64088_2	765911.Thivi_0061	2.508e-192	619.0	COG0589@1|root,COG0730@1|root,COG0589@2|Bacteria,COG0730@2|Bacteria,1NBKV@1224|Proteobacteria,1SHMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
CMS1_k127_64088_13	713586.KB900536_gene2861	7.273e-16	83.0	2EGXE@1|root,329EB@2|Bacteria,1NIPX@1224|Proteobacteria,1SHV3@1236|Gammaproteobacteria,1X1VS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_64088_7	1411123.JQNH01000001_gene3165	1.853e-104	346.0	COG1082@1|root,COG1082@2|Bacteria,1R87Z@1224|Proteobacteria,2U45F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_64088_0	640081.Dsui_0052	1.622e-216	681.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,2KV4V@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS1_k127_64088_11	596153.Alide_4209	2.172e-58	218.0	28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,2VRKU@28216|Betaproteobacteria,4AF7E@80864|Comamonadaceae	28216|Betaproteobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
CMS1_k127_64088_12	596153.Alide_4208	3.878e-36	140.0	COG5642@1|root,COG5642@2|Bacteria,1N2DF@1224|Proteobacteria,2VUY5@28216|Betaproteobacteria,4AFQT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
CMS1_k127_64088_3	1000565.METUNv1_02367	5.085e-180	570.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,2KUQV@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS1_k127_69046_9	570967.JMLV01000008_gene1424	1.142e-07	59.0	COG5662@1|root,COG5662@2|Bacteria,1NG37@1224|Proteobacteria	1224|Proteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_69046_7	570952.ATVH01000016_gene2337	1.403e-47	179.0	COG1595@1|root,COG1595@2|Bacteria,1NRNT@1224|Proteobacteria,2TT5K@28211|Alphaproteobacteria,2JZNH@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_69046_8	1286632.P278_03710	7.434e-36	152.0	COG2044@1|root,COG2044@2|Bacteria,4P2I4@976|Bacteroidetes,1I8SH@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS1_k127_69046_5	1121939.L861_01745	1.402e-84	284.0	COG1765@1|root,COG1765@2|Bacteria,1QUE7@1224|Proteobacteria,1S84Z@1236|Gammaproteobacteria,1XKED@135619|Oceanospirillales	135619|Oceanospirillales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_69046_1	189753.AXAS01000055_gene5700	5.106e-172	565.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria,3JT1R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
CMS1_k127_69046_2	1131553.JIBI01000055_gene188	9.361e-113	377.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_69046_3	331869.BAL199_14437	1.173e-95	321.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,2U3UR@28211|Alphaproteobacteria,4BR6M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS1_k127_69046_0	394221.Mmar10_0677	3.545e-255	814.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2TWVC@28211|Alphaproteobacteria,440R8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_69046_6	329726.AM1_6099	8.892e-69	238.0	COG1309@1|root,COG1309@2|Bacteria,1G58W@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_69046_4	497321.C664_12015	1.464e-86	293.0	COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria,2WGTA@28216|Betaproteobacteria,2KZWK@206389|Rhodocyclales	206389|Rhodocyclales	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_721924_5	1218084.BBJK01000075_gene5239	1.098e-06	57.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,2VXDK@28216|Betaproteobacteria,1K5E1@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS1_k127_721924_4	269797.Mbar_A2931	1.097e-09	70.0	COG3291@1|root,arCOG06836@1|root,arCOG02546@2157|Archaea,arCOG06836@2157|Archaea	2157|Archaea	P	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	BNR_2,CARDB,Kelch_4,PKD,VWA
CMS1_k127_721924_1	1380394.JADL01000001_gene2567	1.045e-66	241.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TXAJ@28211|Alphaproteobacteria,2JWX2@204441|Rhodospirillales	204441|Rhodospirillales	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CMS1_k127_721924_2	1121378.KB899729_gene4105	8.565e-57	211.0	COG4032@1|root,COG4032@2|Bacteria	2|Bacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	MA20_16825	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_N
CMS1_k127_721924_0	1121127.JAFA01000006_gene5482	4.034e-282	876.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VI6D@28216|Betaproteobacteria,1K5TM@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_726727_13	29581.BW37_00218	1.656e-08	56.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,473DE@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_726727_11	2340.JV46_17870	2.137e-39	152.0	COG1765@1|root,COG1765@2|Bacteria,1N1RR@1224|Proteobacteria,1S3KI@1236|Gammaproteobacteria,1J71R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_726727_6	338969.Rfer_4150	1.781e-78	269.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,2W3U8@28216|Betaproteobacteria,4AI76@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_726727_5	290315.Clim_1279	2.77e-85	291.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	hrtA	-	-	ko:K02003,ko:K09814	ko02010,map02010	M00257,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_726727_4	290315.Clim_1280	4.691e-152	508.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	MacB_PCD
CMS1_k127_726727_8	290315.Clim_1281	4.731e-66	241.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_726727_3	292415.Tbd_1734	6.847e-190	625.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,1KSPK@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_726727_15	1123368.AUIS01000005_gene396	0.0003164	52.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_726727_1	626418.bglu_1g09220	4.732e-219	688.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,1K0QI@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS1_k127_726727_7	1157708.KB907450_gene5268	1.747e-73	257.0	COG1414@1|root,COG1414@2|Bacteria,1MXRJ@1224|Proteobacteria,2VNTJ@28216|Betaproteobacteria,4ADV0@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_726727_0	543728.Vapar_3215	1.614e-237	742.0	COG1053@1|root,COG1053@2|Bacteria,1QWW9@1224|Proteobacteria,2VPPG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_726727_2	930166.CD58_18830	5.167e-207	651.0	COG1679@1|root,COG1679@2|Bacteria,1NFH4@1224|Proteobacteria,1S4TW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
CMS1_k127_726727_9	1286093.C266_24393	8.242e-62	234.0	COG1786@1|root,COG1786@2|Bacteria,1RFUH@1224|Proteobacteria,2VSAS@28216|Betaproteobacteria,1KBB8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
CMS1_k127_726727_14	399739.Pmen_1836	1.34e-07	56.0	2BNRX@1|root,32HFE@2|Bacteria,1QF49@1224|Proteobacteria,1TC6U@1236|Gammaproteobacteria,1YJZ0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_744225_21	580332.Slit_1282	1.886e-16	82.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,44VQ8@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS1_k127_744225_22	1304883.KI912532_gene2481	3.467e-15	81.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
CMS1_k127_744225_7	522306.CAP2UW1_1548	1.602e-114	388.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,1KQ9J@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS1_k127_744225_0	323848.Nmul_A1751	1.998e-308	958.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,372EW@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS1_k127_744225_20	1169143.KB911041_gene455	2.384e-19	93.0	COG0695@1|root,COG0695@2|Bacteria,1N82H@1224|Proteobacteria,2VWG7@28216|Betaproteobacteria,1K9F5@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM glutaredoxin 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
CMS1_k127_744225_3	1454004.AW11_03066	1.977e-185	592.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1KQED@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_744225_12	1000565.METUNv1_00626	4.798e-74	259.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,2KUKH@206389|Rhodocyclales	206389|Rhodocyclales	T	Sigma E regulatory protein, MucB RseB	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
CMS1_k127_744225_19	1485544.JQKP01000010_gene786	1.643e-19	97.0	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,44VXX@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Anti sigma-E protein RseA family protein	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
CMS1_k127_744225_11	640081.Dsui_2453	5.108e-96	318.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,2KUG9@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_744225_2	1163617.SCD_n01531	7.038e-206	647.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria	28216|Betaproteobacteria	I	catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_744225_15	1454004.AW11_03060	1.803e-34	133.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,1KQ47@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS1_k127_744225_9	1532557.JL37_08515	1.504e-104	346.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,3T383@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_744225_8	269482.Bcep1808_1041	1.923e-114	392.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1K35C@119060|Burkholderiaceae	28216|Betaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS1_k127_744225_5	1454004.AW11_03057	2.456e-135	438.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,1KPNJ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_744225_4	1288494.EBAPG3_13710	4.543e-147	474.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,372Q2@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS1_k127_744225_18	305700.B447_12464	9.839e-28	112.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,2KX6E@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS1_k127_744225_17	640081.Dsui_2443	4.451e-28	120.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,2KX2U@206389|Rhodocyclales	206389|Rhodocyclales	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS1_k127_744225_14	713586.KB900536_gene795	4.728e-62	222.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1WX51@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_744225_6	1000565.METUNv1_00612	8.061e-122	401.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,2KVMS@206389|Rhodocyclales	206389|Rhodocyclales	OU	signal peptide peptidase	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_744225_16	267608.RSc1043	6.47e-34	136.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2VTX8@28216|Betaproteobacteria,1K7S5@119060|Burkholderiaceae	28216|Betaproteobacteria	P	rieske 2fe-2s	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS1_k127_744225_13	640081.Dsui_2438	6.903e-71	246.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,2KVFF@206389|Rhodocyclales	206389|Rhodocyclales	S	HAD-superfamily hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_744225_10	1123367.C666_08595	4.604e-103	344.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,2KUN8@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_744225_1	159087.Daro_2005	2.023e-266	847.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,2KV38@206389|Rhodocyclales	206389|Rhodocyclales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS1_k127_778079_13	1380394.JADL01000008_gene3465	1.687e-12	67.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JQP4@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase B/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_B
CMS1_k127_778079_11	1121406.JAEX01000009_gene2638	1.959e-53	203.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43AGN@68525|delta/epsilon subdivisions,2X5WH@28221|Deltaproteobacteria,2MGWQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_778079_2	1205680.CAKO01000040_gene1074	7.623e-301	935.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQSU@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_778079_7	1205680.CAKO01000040_gene1073	1.968e-102	338.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,2JQ14@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_778079_8	1131814.JAFO01000001_gene2620	8.452e-93	336.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TR6T@28211|Alphaproteobacteria,3EYQ5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	MA20_26560	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_778079_3	595537.Varpa_0212	1.421e-264	828.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1MY1E@1224|Proteobacteria,2VMZ5@28216|Betaproteobacteria,4AB9X@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_778079_5	1205680.CAKO01000040_gene1070	6.25e-172	552.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria,2JQHT@204441|Rhodospirillales	204441|Rhodospirillales	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_778079_10	1205680.CAKO01000040_gene1067	1.026e-79	278.0	COG2122@1|root,COG2122@2|Bacteria,1MV9Z@1224|Proteobacteria,2TTG1@28211|Alphaproteobacteria,2JRRD@204441|Rhodospirillales	204441|Rhodospirillales	S	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_778079_4	331869.BAL199_15863	1.188e-236	752.0	COG2816@1|root,COG2816@2|Bacteria,1MV1F@1224|Proteobacteria,2TTRT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1180 Pyruvate-formate lyase-activating enzyme	MA20_26535	-	1.3.7.1	ko:K20449	ko00760,ko01120,map00760,map01120	-	R03164	RC02422	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_778079_1	1205680.CAKO01000040_gene1065	0.0	1200.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS1_k127_778079_9	1207063.P24_11547	6.592e-87	303.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TSYF@28211|Alphaproteobacteria,2JS8E@204441|Rhodospirillales	204441|Rhodospirillales	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_778079_0	323848.Nmul_A1150	0.0	1586.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PV5D@1224|Proteobacteria,2WB3J@28216|Betaproteobacteria,37281@32003|Nitrosomonadales	28216|Betaproteobacteria	CEH	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
CMS1_k127_778079_6	497321.C664_04487	1.349e-108	358.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2VHU8@28216|Betaproteobacteria,2KVHF@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_778079_12	1396858.Q666_12405	2.249e-28	116.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria,466YX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS1_k127_78702_26	1380394.JADL01000013_gene680	4.15e-06	51.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2JVT5@204441|Rhodospirillales	204441|Rhodospirillales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PGI,TAL_FSA
CMS1_k127_78702_6	247490.KSU1_C1030	9.096e-176	560.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	treT	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
CMS1_k127_78702_5	1175306.GWL_22240	4.453e-210	658.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VKD1@28216|Betaproteobacteria,475B2@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	acd12	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_78702_28	316275.VSAL_II1055	0.0005501	53.0	COG1266@1|root,COG1266@2|Bacteria,1P0IE@1224|Proteobacteria,1RS9M@1236|Gammaproteobacteria,1XV8N@135623|Vibrionales	135623|Vibrionales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_78702_21	95619.PM1_0216130	7.095e-71	260.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_78702_18	1454004.AW11_00293	1.324e-85	290.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,1KQB6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadB3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_78702_2	522306.CAP2UW1_1069	2.41e-278	863.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,1KQE4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_78702_19	1218074.BAXZ01000010_gene2457	1.176e-84	288.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,1K069@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS1_k127_78702_22	748280.NH8B_1079	2.084e-68	235.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,2KR3R@206351|Neisseriales	206351|Neisseriales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS1_k127_78702_20	640081.Dsui_2483	4.285e-79	272.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,2KVQS@206389|Rhodocyclales	206389|Rhodocyclales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_78702_15	1163617.SCD_n01165	1.747e-104	344.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CMS1_k127_78702_11	640081.Dsui_2797	5.542e-124	417.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,2KUQ6@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS1_k127_78702_3	1163617.SCD_n01163	6.578e-250	807.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_78702_8	323848.Nmul_A2332	4.339e-155	524.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,372BM@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_78702_7	522306.CAP2UW1_3046	6.761e-161	511.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,1KQYZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_78702_1	1163617.SCD_n01160	3.409e-286	897.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Extracellular solute-binding protein	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
CMS1_k127_78702_13	257310.BB4282	5.835e-113	374.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria,3T1RP@506|Alcaligenaceae	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_78702_10	522306.CAP2UW1_2273	9.793e-149	494.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1KQ5X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS1_k127_78702_24	202952.BBLI01000004_gene491	3.059e-10	65.0	2DR59@1|root,33A7S@2|Bacteria,1NMH2@1224|Proteobacteria,1SIVW@1236|Gammaproteobacteria,3NS87@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_78702_23	640081.Dsui_2199	2.257e-32	129.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,2KX2Q@206389|Rhodocyclales	206389|Rhodocyclales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_78702_0	85643.Tmz1t_2563	0.0	1247.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,2KUM5@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_78702_4	1000565.METUNv1_00037	7.725e-221	690.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,2KVAQ@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS1_k127_78702_17	1123392.AQWL01000008_gene1182	3.61e-100	352.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,1KRDV@119069|Hydrogenophilales	119069|Hydrogenophilales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_78702_9	305700.B447_00795	2.436e-150	488.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,2KU9B@206389|Rhodocyclales	206389|Rhodocyclales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS1_k127_78702_16	76114.ebA6809	1.143e-103	343.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,2KUC0@206389|Rhodocyclales	206389|Rhodocyclales	I	phytoene	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_78702_12	1500894.JQNN01000001_gene1126	4.032e-120	394.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,473N2@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_78702_14	1163617.SCD_n01778	3.293e-112	388.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
CMS1_k127_78702_25	279714.FuraDRAFT_1963	3.929e-08	59.0	COG3501@1|root,COG3501@2|Bacteria,1R540@1224|Proteobacteria,2VS00@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Baseplate assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_795120_2	1159870.KB907784_gene2440	7.712e-196	623.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,3T2Q4@506|Alcaligenaceae	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_795120_0	1123060.JONP01000001_gene1375	1.043e-219	705.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JQY7@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_795120_5	1123072.AUDH01000005_gene1662	2.16e-110	368.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,2TUR5@28211|Alphaproteobacteria,2JVHC@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_795120_9	1198452.Jab_2c09360	5.719e-48	183.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
CMS1_k127_795120_1	290397.Adeh_2245	7.722e-214	684.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YTUB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_795120_4	62928.azo1482	3.042e-178	580.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,2KUU4@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
CMS1_k127_795120_8	187272.Mlg_1498	8.813e-56	221.0	COG2267@1|root,COG2267@2|Bacteria,1N2KV@1224|Proteobacteria	1224|Proteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_795120_10	323848.Nmul_A2249	3.955e-22	98.0	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria,373H6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_795120_3	1031711.RSPO_c01689	1.507e-190	608.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,2VJ3Y@28216|Betaproteobacteria,1K165@119060|Burkholderiaceae	28216|Betaproteobacteria	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
CMS1_k127_795120_6	76114.ebA4050	1.602e-104	344.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VNV2@28216|Betaproteobacteria,2KUPV@206389|Rhodocyclales	206389|Rhodocyclales	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
CMS1_k127_795120_7	1348657.M622_11920	4.721e-97	337.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VHB6@28216|Betaproteobacteria,2KUMZ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_796308_0	640081.Dsui_2385	0.0	1086.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,2KVGD@206389|Rhodocyclales	206389|Rhodocyclales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_796308_4	1485544.JQKP01000002_gene1662	4.787e-78	271.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,44VGQ@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CMS1_k127_796308_7	580332.Slit_2230	3.859e-62	231.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,44VPY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CMS1_k127_796308_8	1122604.JONR01000014_gene215	1.371e-47	192.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S7MT@1236|Gammaproteobacteria,1X6HS@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
CMS1_k127_796308_9	497321.C664_00865	2.642e-35	141.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,2KWXS@206389|Rhodocyclales	206389|Rhodocyclales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS1_k127_796308_10	1123368.AUIS01000003_gene1766	7.17e-28	124.0	COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria	1224|Proteobacteria	U	General secretion pathway protein C	xcsC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CMS1_k127_796308_2	1123368.AUIS01000003_gene1765	2.554e-174	583.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	General Secretion Pathway protein	xcsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS1_k127_796308_1	1123368.AUIS01000003_gene1764	2.731e-211	672.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2NCBG@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
CMS1_k127_796308_3	713586.KB900536_gene2364	1.945e-115	405.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_796308_6	1218075.BAYA01000004_gene1463	3.186e-62	217.0	COG2165@1|root,COG2165@2|Bacteria,1RBWD@1224|Proteobacteria,2VQMF@28216|Betaproteobacteria,1K70E@119060|Burkholderiaceae	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_796308_14	29581.BW37_02975	1.873e-11	75.0	COG2165@1|root,COG2165@2|Bacteria,1N8AD@1224|Proteobacteria,2VWBA@28216|Betaproteobacteria,474NB@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Type II transport protein GspH	gspH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CMS1_k127_796308_11	76114.ebA4908	5.813e-21	100.0	COG2165@1|root,COG2165@2|Bacteria,1N0C2@1224|Proteobacteria,2VVJ8@28216|Betaproteobacteria,2KZP4@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretion system (T2SS), protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
CMS1_k127_796308_12	396588.Tgr7_0234	6.534e-19	98.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1WZPE@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein J	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CMS1_k127_796308_5	1163617.SCD_n01322	3.555e-68	243.0	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,2VS9P@28216|Betaproteobacteria	28216|Betaproteobacteria	U	general secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS1_k127_796308_13	1192124.LIG30_1238	7.165e-13	81.0	COG3297@1|root,COG3297@2|Bacteria,1N6IJ@1224|Proteobacteria,2VTP1@28216|Betaproteobacteria,1JZS7@119060|Burkholderiaceae	28216|Betaproteobacteria	U	General secretion pathway protein L	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
CMS1_k127_839299_2	935948.KE386494_gene944	1.311e-92	312.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_839299_0	1411123.JQNH01000001_gene3811	1.153e-170	542.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_839299_1	404589.Anae109_1864	2.584e-135	439.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
CMS1_k127_839299_3	215803.DB30_6542	2.295e-64	241.0	COG0500@1|root,COG2226@2|Bacteria,1RC36@1224|Proteobacteria,42UDA@68525|delta/epsilon subdivisions,2WQHW@28221|Deltaproteobacteria,2YV8X@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_839299_4	420662.Mpe_A1898	2.258e-39	149.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,1KITC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_917712_1	1174528.JH992898_gene1074	2.441e-38	149.0	COG3791@1|root,COG3791@2|Bacteria,1G9JF@1117|Cyanobacteria,1JM2B@1189|Stigonemataceae	1117|Cyanobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_917712_2	1502770.JQMG01000001_gene488	8.667e-18	93.0	COG0810@1|root,COG0810@2|Bacteria,1PE9F@1224|Proteobacteria,2VXP2@28216|Betaproteobacteria,2KNAJ@206350|Nitrosomonadales	206350|Nitrosomonadales	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_917712_0	1205680.CAKO01000030_gene4881	3.274e-162	523.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TRRY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	MA20_04660	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_927227_7	114615.BRADO3026	1.365e-63	222.0	COG0061@1|root,COG0061@2|Bacteria,1NBI3@1224|Proteobacteria,2TUCV@28211|Alphaproteobacteria,3JTFG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
CMS1_k127_927227_13	795359.TOPB45_0890	1.361e-20	96.0	COG0526@1|root,COG0526@2|Bacteria,2GI1G@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
CMS1_k127_927227_3	795359.TOPB45_0889	8.238e-137	443.0	COG0701@1|root,COG0701@2|Bacteria,2GHF9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS1_k127_927227_9	1492922.GY26_17040	5.05e-29	116.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1J6VM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_927227_4	330214.NIDE1759	1.895e-96	324.0	COG0778@1|root,COG0778@2|Bacteria,3J0XZ@40117|Nitrospirae	40117|Nitrospirae	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_927227_5	330214.NIDE1759	4.396e-89	305.0	COG0778@1|root,COG0778@2|Bacteria,3J0XZ@40117|Nitrospirae	40117|Nitrospirae	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_927227_0	243233.MCA0127	8.427e-241	755.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XEME@135618|Methylococcales	135618|Methylococcales	S	pfam abc	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_927227_10	1235457.C404_00285	1.81e-28	119.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1K9CX@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_927227_6	1122197.ATWI01000009_gene1646	5.62e-69	248.0	COG3203@1|root,COG3203@2|Bacteria,1RIIY@1224|Proteobacteria	1224|Proteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
CMS1_k127_927227_2	640511.BC1002_1607	1.543e-141	469.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,1K51A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
CMS1_k127_927227_1	522306.CAP2UW1_4250	1.789e-160	520.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2WGNM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
CMS1_k127_927227_11	1157708.KB907450_gene6136	1.361e-22	107.0	COG2197@1|root,COG2197@2|Bacteria,1R2TM@1224|Proteobacteria,2VJ7V@28216|Betaproteobacteria,4AF37@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_927227_8	1266925.JHVX01000009_gene36	3.675e-56	207.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,2VR84@28216|Betaproteobacteria,372P3@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
CMS1_k127_927227_12	931627.MycrhDRAFT_5562	3.233e-21	108.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_931373_45	404380.Gbem_2532	5.222e-32	133.0	2DFV1@1|root,2ZT9B@2|Bacteria	2|Bacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
CMS1_k127_931373_34	1123393.KB891330_gene862	1.208e-46	172.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,2VU7D@28216|Betaproteobacteria,1KT5V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
CMS1_k127_931373_37	1458275.AZ34_09990	2.048e-41	168.0	COG3678@1|root,COG3678@2|Bacteria,1MZKK@1224|Proteobacteria,2W3Z1@28216|Betaproteobacteria,4AIAU@80864|Comamonadaceae	28216|Betaproteobacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
CMS1_k127_931373_27	1095769.CAHF01000022_gene158	1.011e-59	220.0	COG0664@1|root,COG0664@2|Bacteria,1NCGM@1224|Proteobacteria,2VWGW@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_931373_25	1158292.JPOE01000005_gene411	3.331e-75	263.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,2VJP1@28216|Betaproteobacteria,1KKGS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Glutamine amido-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
CMS1_k127_931373_47	331869.BAL199_29090	1.753e-28	121.0	COG3791@1|root,COG3791@2|Bacteria	2|Bacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_931373_19	96561.Dole_2995	3.679e-89	304.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,2MKJX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS1_k127_931373_6	1304275.C41B8_10043	2.434e-167	536.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_931373_20	1380394.JADL01000011_gene3974	5.145e-88	297.0	COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2TSQ1@28211|Alphaproteobacteria,2JRQ3@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_931373_48	33876.JNXY01000034_gene841	1.369e-25	116.0	COG1246@1|root,COG1246@2|Bacteria,2HWIA@201174|Actinobacteria,4DIUD@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_931373_32	1177928.TH2_18751	1.055e-49	182.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2UBYB@28211|Alphaproteobacteria,2JTBY@204441|Rhodospirillales	204441|Rhodospirillales	T	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
CMS1_k127_931373_12	1458275.AZ34_07565	2.328e-117	385.0	COG0789@1|root,COG0789@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,4ACBQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
CMS1_k127_931373_5	887062.HGR_05419	2.953e-169	537.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,4ACT9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_931373_33	765912.Thimo_2419	7.205e-49	181.0	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,1SCY7@1236|Gammaproteobacteria,1WYDM@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
CMS1_k127_931373_15	887062.HGR_05429	4.278e-111	365.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2VQHY@28216|Betaproteobacteria,4ADH5@80864|Comamonadaceae	28216|Betaproteobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
CMS1_k127_931373_26	1458275.AZ34_07545	8.953e-70	254.0	COG4338@1|root,COG4338@2|Bacteria,1N3G5@1224|Proteobacteria,2VUMZ@28216|Betaproteobacteria,4AF09@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_931373_22	887062.HGR_05439	1.241e-79	269.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,2VTSY@28216|Betaproteobacteria,4AJFE@80864|Comamonadaceae	28216|Betaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
CMS1_k127_931373_7	1458275.AZ34_07535	1.129e-153	499.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VMFC@28216|Betaproteobacteria,4AFKG@80864|Comamonadaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS1_k127_931373_1	887062.HGR_05449	7.15e-217	697.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
CMS1_k127_931373_18	1429851.X548_09280	6.574e-90	303.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1X449@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
CMS1_k127_931373_3	887062.HGR_05459	5.506e-214	683.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,4AC6Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_931373_38	204773.HEAR3287	4.292e-41	163.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,474NZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_931373_40	375286.mma_1583	8.225e-38	148.0	COG1787@1|root,COG1787@2|Bacteria,1RGGQ@1224|Proteobacteria,2VTJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	V	restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
CMS1_k127_931373_23	757424.Hsero_1853	2.581e-79	282.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,473QK@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Serine hydrolase (FSH1)	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS1_k127_931373_21	1205680.CAKO01000038_gene1573	4.731e-81	285.0	COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2U0AF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_931373_44	221288.JH992901_gene1687	3.255e-33	134.0	COG1695@1|root,COG1695@2|Bacteria,1GDRG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_931373_4	76114.ebA1004	1.749e-183	585.0	COG0657@1|root,COG0657@2|Bacteria,1MV89@1224|Proteobacteria,2VJJC@28216|Betaproteobacteria,2M03F@206389|Rhodocyclales	206389|Rhodocyclales	I	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
CMS1_k127_931373_13	522306.CAP2UW1_2430	1.536e-113	372.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL
CMS1_k127_931373_30	522306.CAP2UW1_1158	3.212e-55	199.0	COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,2VUGF@28216|Betaproteobacteria,1KR15@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS1_k127_931373_39	196367.JNFG01000011_gene6025	1.245e-39	170.0	COG2267@1|root,COG2267@2|Bacteria,1PECQ@1224|Proteobacteria,2W6QB@28216|Betaproteobacteria,1KCAG@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_931373_49	591158.SSMG_07550	2.581e-12	72.0	COG0543@1|root,COG1017@1|root,COG0543@2|Bacteria,COG1017@2|Bacteria,2GKXT@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the globin family	fhbA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Globin,NAD_binding_1
CMS1_k127_931373_31	1279019.ARQK01000042_gene2026	5.28e-55	197.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_931373_43	1123368.AUIS01000006_gene647	7.82e-36	142.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,2ND8Z@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_931373_10	1485544.JQKP01000002_gene1413	1.342e-121	406.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS1_k127_931373_17	1454004.AW11_00066	4.147e-90	306.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_931373_8	395494.Galf_2066	1.71e-145	471.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_931373_9	395494.Galf_2067	4.892e-142	480.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,44UZP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_931373_2	1469245.JFBG01000062_gene2271	4.621e-215	686.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_931373_11	713586.KB900536_gene844	1.279e-120	396.0	COG2358@1|root,COG2358@2|Bacteria,1NRSC@1224|Proteobacteria	1224|Proteobacteria	S	TRAP transporter, solute receptor (TAXI family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
CMS1_k127_931373_36	1095769.CAHF01000025_gene608	6.303e-42	158.0	COG0278@1|root,COG0278@2|Bacteria,1RKVH@1224|Proteobacteria,2VTC6@28216|Betaproteobacteria,4790V@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS1_k127_931373_16	936455.KI421499_gene1003	3.009e-99	354.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2TTF6@28211|Alphaproteobacteria,3JV1J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	MA20_38220	-	1.14.14.12	ko:K16047	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
CMS1_k127_931373_46	1040989.AWZU01000031_gene3918	1.309e-29	124.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2U65K@28211|Alphaproteobacteria,3JY8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_931373_41	748247.AZKH_1551	1.202e-37	162.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,2KWRE@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_931373_14	1122185.N792_05765	7.279e-112	390.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,1RQUG@1236|Gammaproteobacteria,1X59Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
CMS1_k127_931373_35	1384054.N790_09035	1.451e-42	172.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1X6M0@135614|Xanthomonadales	135614|Xanthomonadales	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
CMS1_k127_931373_50	330214.NIDE4295	1.439e-11	78.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
CMS1_k127_931373_28	1452718.JBOY01000051_gene1192	1.753e-56	206.0	COG0483@1|root,COG1397@1|root,COG0483@2|Bacteria,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria	1224|Proteobacteria	O	PFAM ADP-ribosylation Crystallin J1	draG	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,Inositol_P
CMS1_k127_931373_24	316067.Geob_0941	2.136e-75	269.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,43TKF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_931373_42	395494.Galf_1701	7.645e-36	139.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,44WKZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CMS1_k127_931373_0	748247.AZKH_3506	2.293e-237	756.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,2KUX1@206389|Rhodocyclales	206389|Rhodocyclales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_931373_29	243365.CV_1113	6.13e-56	199.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,2KPMW@206351|Neisseriales	206351|Neisseriales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_936301_3	85643.Tmz1t_0247	5.6e-40	151.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria,2KXF3@206389|Rhodocyclales	206389|Rhodocyclales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_936301_1	472759.Nhal_0265	4.936e-161	529.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1WW2F@135613|Chromatiales	135613|Chromatiales	P	Chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
CMS1_k127_936301_2	1458275.AZ34_05040	3.03e-72	253.0	COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2VNYN@28216|Betaproteobacteria,4AEY6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_936301_0	1218084.BBJK01000135_gene7223	5.197e-255	792.0	COG0492@1|root,COG0492@2|Bacteria,1MVX2@1224|Proteobacteria,2VM3V@28216|Betaproteobacteria,1K4AE@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
CMS1_k127_945766_3	1144275.COCOR_02790	2.351e-177	574.0	COG0436@1|root,COG0436@2|Bacteria,1QE0D@1224|Proteobacteria	1224|Proteobacteria	E	aminotransferase	-	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
CMS1_k127_945766_1	335659.S23_18640	3.19e-228	719.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,3JT6H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malic enzyme, NAD binding domain	MA20_02490	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
CMS1_k127_945766_7	1380355.JNIJ01000001_gene3989	4.842e-100	345.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3JU16@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_945766_6	1038859.AXAU01000003_gene6201	6.223e-108	373.0	COG0411@1|root,COG0411@2|Bacteria,1NP6N@1224|Proteobacteria,2U27F@28211|Alphaproteobacteria,3K5XU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_945766_5	1380355.JNIJ01000001_gene3987	2.497e-132	449.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,3JW7Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_945766_4	1317124.DW2_03184	2.976e-137	458.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,2XNSE@285107|Thioclava	28211|Alphaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_945766_2	1038859.AXAU01000003_gene6198	7.467e-180	571.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2TT0T@28211|Alphaproteobacteria,3JXYC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_945766_0	1163617.SCD_n02724	0.0	1615.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VJK5@28216|Betaproteobacteria	28216|Betaproteobacteria	G	pyruvate phosphate dikinase	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_945766_8	640081.Dsui_0298	4.556e-99	336.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,2VI48@28216|Betaproteobacteria,2KXHY@206389|Rhodocyclales	206389|Rhodocyclales	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS1_k127_945766_10	748247.AZKH_1172	1.557e-30	124.0	2DNV8@1|root,32ZAX@2|Bacteria,1R3MW@1224|Proteobacteria,2VWAR@28216|Betaproteobacteria,2KWYT@206389|Rhodocyclales	206389|Rhodocyclales	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_945766_9	987059.RBXJA2T_19271	6.127e-31	127.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2VJS5@28216|Betaproteobacteria,1KJ5V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
## 3305 queries scanned
## Total time (seconds): 46.6720609664917
## Rate: 70.81 q/s