## Fri Nov  8 06:21:53 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS1_bin.86.fa -m mmseqs --itype genome -o CMS1_bin.86 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS1_bin.86 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS1_k127_103999_0	1396141.BATP01000022_gene395	2.315e-55	199.0	COG1621@1|root,COG2382@1|root,COG1621@2|Bacteria,COG2382@2|Bacteria,46U0H@74201|Verrucomicrobia,2IVDH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS1_k127_103999_3	1195236.CTER_0189	3.184e-07	62.0	COG3595@1|root,COG3595@2|Bacteria,1UJUF@1239|Firmicutes,25FA3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_103999_2	694427.Palpr_2142	3.009e-08	63.0	2AFFZ@1|root,315G5@2|Bacteria,4PHMR@976|Bacteroidetes,2G1HZ@200643|Bacteroidia,22YWC@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_103999_1	880526.KE386488_gene1323	2.39e-25	115.0	COG1595@1|root,COG1595@2|Bacteria,4NQE0@976|Bacteroidetes,2FP26@200643|Bacteroidia,22VCN@171550|Rikenellaceae	976|Bacteroidetes	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1040742_1	452637.Oter_3833	1.287e-177	561.0	COG2804@1|root,COG2804@2|Bacteria,46TEW@74201|Verrucomicrobia,3K94U@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_1040742_5	1499967.BAYZ01000018_gene6342	7.29e-55	200.0	COG3506@1|root,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	yjl217W	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
CMS1_k127_1040742_4	583355.Caka_0388	3.73e-99	331.0	COG0151@1|root,COG0151@2|Bacteria,46SGJ@74201|Verrucomicrobia,3K7MF@414999|Opitutae	414999|Opitutae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS1_k127_1040742_7	583355.Caka_0388	5.371e-42	157.0	COG0151@1|root,COG0151@2|Bacteria,46SGJ@74201|Verrucomicrobia,3K7MF@414999|Opitutae	414999|Opitutae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS1_k127_1040742_2	278957.ABEA03000014_gene2533	1.387e-166	536.0	COG0277@1|root,COG0277@2|Bacteria,46UHB@74201|Verrucomicrobia,3K7CZ@414999|Opitutae	414999|Opitutae	C	PFAM FAD linked oxidase domain protein	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_1040742_6	1158294.JOMI01000009_gene1273	3.642e-54	199.0	COG0454@1|root,COG0456@2|Bacteria,4NRS3@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS1_k127_1040742_8	278957.ABEA03000006_gene4189	8.103e-27	120.0	COG4272@1|root,COG4272@2|Bacteria,46YG6@74201|Verrucomicrobia,3K9I0@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
CMS1_k127_1040742_3	794903.OPIT5_15890	3.109e-110	362.0	COG0730@1|root,COG0730@2|Bacteria,46V52@74201|Verrucomicrobia,3K9AP@414999|Opitutae	414999|Opitutae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_1040742_0	1033732.CAHI01000015_gene490	2.662e-320	996.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,22V18@171550|Rikenellaceae	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS1_k127_1046790_0	382464.ABSI01000005_gene969	1.232e-107	356.0	COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,2ITKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
CMS1_k127_1046790_2	644282.Deba_0583	3.021e-51	195.0	COG0840@1|root,COG0840@2|Bacteria,1RE5G@1224|Proteobacteria,42SBI@68525|delta/epsilon subdivisions,2WPRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
CMS1_k127_1046790_1	452637.Oter_3498	6.342e-95	314.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_1061207_0	452637.Oter_1454	2.898e-136	442.0	COG0841@1|root,COG0841@2|Bacteria,46SER@74201|Verrucomicrobia	74201|Verrucomicrobia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_1061207_2	243231.GSU0392	7.756e-33	140.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,43UXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_1061207_3	452637.Oter_1458	9.766e-18	86.0	COG0607@1|root,315D1@2|Bacteria,46TC5@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_1061207_1	484770.UFO1_4423	3.076e-48	181.0	COG1028@1|root,COG1028@2|Bacteria,1TS27@1239|Firmicutes,4H6ZW@909932|Negativicutes	909932|Negativicutes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_107875_5	309807.SRU_0342	1.99e-36	146.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	pqiB	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_107875_0	452637.Oter_2315	5.056e-174	559.0	COG2211@1|root,COG2211@2|Bacteria,46UFW@74201|Verrucomicrobia	74201|Verrucomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS1_k127_107875_8	583355.Caka_0774	4.454e-26	119.0	COG0226@1|root,COG0226@2|Bacteria,46XUS@74201|Verrucomicrobia,3K8AS@414999|Opitutae	414999|Opitutae	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_107875_3	204669.Acid345_3027	7.835e-89	301.0	COG0008@1|root,COG0008@2|Bacteria,3Y4TS@57723|Acidobacteria,2JKAU@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_107875_6	930169.B5T_01174	4.27e-32	135.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,1XNUR@135619|Oceanospirillales	135619|Oceanospirillales	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS1_k127_107875_7	234267.Acid_0972	4.45e-26	117.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria	57723|Acidobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_107875_1	926561.KB900617_gene2327	1.605e-152	511.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WAH1@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
CMS1_k127_107875_2	382464.ABSI01000023_gene556	1.421e-150	484.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,2ITTX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS1_k127_107875_4	765911.Thivi_3566	9.363e-84	285.0	28JYD@1|root,2Z9NN@2|Bacteria,1MV9T@1224|Proteobacteria,1S18H@1236|Gammaproteobacteria,1WWSD@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_107875_9	278957.ABEA03000017_gene2957	8.055e-12	71.0	COG0457@1|root,COG0457@2|Bacteria,46XYV@74201|Verrucomicrobia,3K8N3@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1086693_5	583355.Caka_1595	1.304e-64	226.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,3K88J@414999|Opitutae	414999|Opitutae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CMS1_k127_1086693_4	382464.ABSI01000010_gene3324	4.425e-83	287.0	COG1893@1|root,COG1893@2|Bacteria,46SK2@74201|Verrucomicrobia,2IU3H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_1086693_2	794903.OPIT5_04120	1.497e-107	353.0	COG0528@1|root,COG0528@2|Bacteria,46S4W@74201|Verrucomicrobia,3K7UI@414999|Opitutae	414999|Opitutae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_1086693_1	926549.KI421517_gene23	3.923e-143	469.0	COG2755@1|root,COG2755@2|Bacteria,4NK31@976|Bacteroidetes,47YGY@768503|Cytophagia	976|Bacteroidetes	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_88,SASA
CMS1_k127_1086693_6	497964.CfE428DRAFT_0735	6.225e-54	197.0	COG0637@1|root,COG0637@2|Bacteria,46SWS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	HAD-hyrolase-like	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_1086693_0	278957.ABEA03000027_gene1656	1.559e-160	519.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia,3K7EP@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1086693_3	382464.ABSI01000005_gene1271	2.155e-96	336.0	COG1639@1|root,COG3437@1|root,COG1639@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS1_k127_1086693_7	56780.SYN_00535	2.318e-45	171.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2MS0Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS1_k127_1089828_1	99598.Cal7507_3527	4.487e-77	263.0	2DC2H@1|root,2ZCMU@2|Bacteria,1G35D@1117|Cyanobacteria,1HJFS@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1089828_2	1173022.Cri9333_4527	4.869e-12	70.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	pspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03969	-	-	-	-	ko00000	-	-	-	DUF4139,DUF4140,LRAT,PspA_IM30
CMS1_k127_1089828_0	761193.Runsl_1123	5.102e-140	453.0	COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,47KKU@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_1131418_1	1397528.Q671_08010	1.28e-23	115.0	COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales	135619|Oceanospirillales	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1131418_0	301.JNHE01000016_gene4517	1.715e-24	109.0	COG3499@1|root,COG3499@2|Bacteria,1MZJ7@1224|Proteobacteria,1S3NI@1236|Gammaproteobacteria,1YG6D@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Phage P2 GpU	-	-	-	ko:K06906	-	-	-	-	ko00000	-	-	-	Phage_P2_GpU
CMS1_k127_1131418_2	1216966.BAUC01000019_gene872	8.955e-09	68.0	COG5004@1|root,COG5004@2|Bacteria,1N81H@1224|Proteobacteria,1SCK4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	tail protein x	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_X
CMS1_k127_1166087_1	264732.Moth_0810	2.136e-83	286.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,42FS6@68295|Thermoanaerobacterales	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS1_k127_1166087_0	264732.Moth_1194	3.006e-195	628.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
CMS1_k127_1187452_5	1122604.JONR01000016_gene4378	3.47e-38	149.0	COG1595@1|root,COG1595@2|Bacteria,1RD9G@1224|Proteobacteria,1S82R@1236|Gammaproteobacteria,1X7PT@135614|Xanthomonadales	135614|Xanthomonadales	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1187452_2	382464.ABSI01000010_gene3370	1.338e-61	217.0	COG1949@1|root,COG1949@2|Bacteria	2|Bacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CMS1_k127_1187452_6	247490.KSU1_D0305	9.101e-23	102.0	COG3784@1|root,COG3784@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1318)	ydbL	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
CMS1_k127_1187452_8	278957.ABEA03000191_gene1027	8.191e-05	48.0	2BTRV@1|root,32NZ2@2|Bacteria,46XWH@74201|Verrucomicrobia,3K8GR@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1187452_1	583355.Caka_1733	1.289e-86	300.0	COG1929@1|root,COG1929@2|Bacteria,46TGW@74201|Verrucomicrobia,3K730@414999|Opitutae	414999|Opitutae	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
CMS1_k127_1187452_0	240016.ABIZ01000001_gene2591	9.166e-122	402.0	COG0399@1|root,COG0399@2|Bacteria,46SEI@74201|Verrucomicrobia,2ITTP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_1187452_4	794903.OPIT5_16140	1.625e-47	189.0	COG3307@1|root,COG3307@2|Bacteria,46XGV@74201|Verrucomicrobia,3K792@414999|Opitutae	414999|Opitutae	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_1187452_7	382464.ABSI01000005_gene1347	3.176e-20	94.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,2IUZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
CMS1_k127_1187452_3	926550.CLDAP_30280	8.962e-51	193.0	COG2971@1|root,COG2971@2|Bacteria,2G6Y6@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS1_k127_1191253_0	713586.KB900536_gene1524	1.336e-185	589.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RMP7@1236|Gammaproteobacteria,1X1AI@135613|Chromatiales	135613|Chromatiales	S	HipA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
CMS1_k127_1191253_2	1396141.BATP01000032_gene4348	1.081e-05	55.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF637,He_PIG,Laminin_G_3,PATR,SdrD_B
CMS1_k127_1191253_1	710243.XP_007596941.1	1.253e-21	103.0	2C3KP@1|root,2SHWK@2759|Eukaryota,39T1S@33154|Opisthokonta,3NY2E@4751|Fungi,3QPUI@4890|Ascomycota,2184J@147550|Sordariomycetes,1EUBB@1028384|Glomerellales	4751|Fungi	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_1,CBM_6,Glyco_hydro_43
CMS1_k127_1191286_4	710243.XP_007596941.1	7.041e-24	104.0	2C3KP@1|root,2SHWK@2759|Eukaryota,39T1S@33154|Opisthokonta,3NY2E@4751|Fungi,3QPUI@4890|Ascomycota,2184J@147550|Sordariomycetes,1EUBB@1028384|Glomerellales	4751|Fungi	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_1,CBM_6,Glyco_hydro_43
CMS1_k127_1191286_1	794903.OPIT5_22970	8.604e-57	213.0	COG0352@1|root,COG0352@2|Bacteria,46YYS@74201|Verrucomicrobia,3K9I5@414999|Opitutae	414999|Opitutae	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_1191286_0	794903.OPIT5_22965	5.474e-98	328.0	COG2145@1|root,COG2145@2|Bacteria,46V6B@74201|Verrucomicrobia,3K9BY@414999|Opitutae	414999|Opitutae	H	Hydroxyethylthiazole kinase family	-	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
CMS1_k127_1191286_2	765913.ThidrDRAFT_2564	8.087e-50	188.0	COG2875@1|root,COG2875@2|Bacteria,1RACR@1224|Proteobacteria,1SPSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	-	-	-	-	-	-	-	-	-	-	TP_methylase
CMS1_k127_1191286_3	1121007.AUML01000019_gene737	1.447e-42	169.0	COG2905@1|root,COG2905@2|Bacteria,4NDZ8@976|Bacteroidetes,1HWQU@117743|Flavobacteriia	976|Bacteroidetes	T	signal-transduction protein containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS1_k127_1240041_4	765912.Thimo_1109	6.704e-98	331.0	COG5438@1|root,COG5438@2|Bacteria,1MYCQ@1224|Proteobacteria,1S1SI@1236|Gammaproteobacteria,1WXCA@135613|Chromatiales	135613|Chromatiales	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
CMS1_k127_1240041_3	592027.CLG_A0035	1.015e-99	336.0	COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,247JI@186801|Clostridia,36QS9@31979|Clostridiaceae	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_1240041_1	414684.RC1_0291	1.487e-180	593.0	COG4773@1|root,COG4773@2|Bacteria,1Q323@1224|Proteobacteria,2TW33@28211|Alphaproteobacteria,2JX9W@204441|Rhodospirillales	28211|Alphaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_1240041_2	1123020.AUIE01000026_gene4930	3.578e-105	353.0	COG3568@1|root,COG3568@2|Bacteria,1RJX3@1224|Proteobacteria,1S7J9@1236|Gammaproteobacteria,1YFJU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_1240041_0	794903.OPIT5_12835	1.473e-202	636.0	COG0027@1|root,COG0027@2|Bacteria,46ZBN@74201|Verrucomicrobia,3K78S@414999|Opitutae	414999|Opitutae	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
CMS1_k127_1240041_5	95619.PM1_0222805	8.96e-65	228.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	RND efflux system, outer membrane lipoprotein	oprM	-	-	ko:K18139,ko:K18147,ko:K18323	ko01501,ko02020,ko02024,map01501,map02020,map02024	M00642,M00643,M00645,M00647,M00649,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2,2.A.6.2.40,2.A.6.2.41	-	-	OEP
CMS1_k127_1258238_0	583355.Caka_0005	8.414e-74	254.0	COG0500@1|root,COG2226@2|Bacteria,46STX@74201|Verrucomicrobia,3K7U4@414999|Opitutae	414999|Opitutae	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS1_k127_1258238_3	583355.Caka_0411	1.749e-47	176.0	2CKAQ@1|root,34BNJ@2|Bacteria,46WDC@74201|Verrucomicrobia,3K83J@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1258238_1	395493.BegalDRAFT_0321	1.89e-63	229.0	28HGQ@1|root,2Z7SH@2|Bacteria,1R6PH@1224|Proteobacteria,1RYGY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1258238_2	583355.Caka_1041	2.69e-60	216.0	COG2159@1|root,COG2159@2|Bacteria,46VK5@74201|Verrucomicrobia,3K854@414999|Opitutae	414999|Opitutae	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_1277006_5	929712.KI912613_gene3514	0.0008692	46.0	COG0438@1|root,COG0438@2|Bacteria,2HEVG@201174|Actinobacteria,4CSMZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1277006_2	468059.AUHA01000002_gene505	4.497e-43	171.0	COG0438@1|root,COG0438@2|Bacteria,4NN7D@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1277006_0	1234595.C725_2934	6.458e-100	338.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2TQJM@28211|Alphaproteobacteria,4BS0G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1277006_3	1150600.ADIARSV_2693	1.159e-29	125.0	COG1045@1|root,COG1045@2|Bacteria,4NJ0X@976|Bacteroidetes,1J14X@117747|Sphingobacteriia	976|Bacteroidetes	E	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
CMS1_k127_1277006_1	1121447.JONL01000004_gene2848	3.526e-85	297.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,42MJF@68525|delta/epsilon subdivisions,2WJYR@28221|Deltaproteobacteria,2M9NA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1277006_4	278957.ABEA03000019_gene1874	2.2e-21	99.0	COG0840@1|root,COG0840@2|Bacteria,46YKB@74201|Verrucomicrobia,3K9S0@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal
CMS1_k127_1283893_1	452637.Oter_0482	5.234e-54	194.0	COG1905@1|root,COG1905@2|Bacteria,46VG7@74201|Verrucomicrobia,3K7Z6@414999|Opitutae	414999|Opitutae	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS1_k127_1283893_2	404589.Anae109_1713	3.782e-46	186.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	cytochrome c	ccsBA	GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS1_k127_1283893_0	452637.Oter_2836	5.28e-183	585.0	COG0541@1|root,COG0541@2|Bacteria,46SIU@74201|Verrucomicrobia,3K7HT@414999|Opitutae	414999|Opitutae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS1_k127_1289508_0	382464.ABSI01000010_gene3407	8.153e-217	685.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_1289508_1	583355.Caka_2914	1.221e-181	577.0	COG0001@1|root,COG0001@2|Bacteria,46TKU@74201|Verrucomicrobia,3K7DQ@414999|Opitutae	414999|Opitutae	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_1289508_3	1101189.AQUO01000001_gene1347	1.477e-13	76.0	COG3293@1|root,COG3293@2|Bacteria,1RKZ9@1224|Proteobacteria,2UAD3@28211|Alphaproteobacteria,2PX7B@265|Paracoccus	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
CMS1_k127_1289508_2	452637.Oter_0815	3.01e-19	96.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia,3K9B6@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
CMS1_k127_1302425_3	688270.Celal_4194	2.124e-42	169.0	COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,1I02I@117743|Flavobacteriia,1F9WZ@104264|Cellulophaga	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1302425_0	583355.Caka_1317	1.123e-168	539.0	COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,3KA2N@414999|Opitutae	414999|Opitutae	I	Beta-ketoacyl synthase, N-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_1302425_5	452637.Oter_3788	2.502e-21	98.0	COG0236@1|root,COG0236@2|Bacteria,46VWP@74201|Verrucomicrobia,3K882@414999|Opitutae	414999|Opitutae	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS1_k127_1302425_2	382464.ABSI01000020_gene198	3.704e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2ITSE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_1302425_7	1236959.BAMT01000003_gene618	3.115e-15	83.0	2E78G@1|root,331S4@2|Bacteria,1N78C@1224|Proteobacteria,2VW2X@28216|Betaproteobacteria,2KNWW@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF3016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3016
CMS1_k127_1302425_6	794903.OPIT5_05160	1.623e-16	92.0	COG3137@1|root,COG3137@2|Bacteria,46YP4@74201|Verrucomicrobia,3K9X6@414999|Opitutae	414999|Opitutae	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS1_k127_1302425_1	452637.Oter_2487	2.263e-126	412.0	COG0113@1|root,COG0113@2|Bacteria,46S91@74201|Verrucomicrobia,3K7HG@414999|Opitutae	414999|Opitutae	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS1_k127_1302425_4	583355.Caka_2612	1.487e-35	139.0	COG0144@1|root,COG0144@2|Bacteria,46V5S@74201|Verrucomicrobia,3K7YH@414999|Opitutae	414999|Opitutae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
CMS1_k127_1332669_0	583355.Caka_0857	1.383e-129	430.0	COG0591@1|root,COG0591@2|Bacteria,46ZB9@74201|Verrucomicrobia,3K8WD@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_1332669_3	452637.Oter_0711	2.02e-59	211.0	COG0041@1|root,COG0041@2|Bacteria,46SRV@74201|Verrucomicrobia,3K82K@414999|Opitutae	414999|Opitutae	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS1_k127_1332669_9	794903.OPIT5_27545	7.823e-20	91.0	2EPKD@1|root,33H70@2|Bacteria,46WC0@74201|Verrucomicrobia,3K89T@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1332669_7	879212.DespoDRAFT_00165	2.969e-27	114.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MKJV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_1332669_4	382464.ABSI01000010_gene3678	7.397e-57	207.0	COG0596@1|root,COG0596@2|Bacteria,46V2G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha/beta hydrolase fold	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_1332669_6	382464.ABSI01000005_gene1127	6.543e-32	134.0	COG0810@1|root,COG0810@2|Bacteria,46W4X@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS1_k127_1332669_1	452637.Oter_3364	3.778e-112	374.0	COG0404@1|root,COG0404@2|Bacteria,46UNP@74201|Verrucomicrobia,3K7HR@414999|Opitutae	414999|Opitutae	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_1332669_2	583355.Caka_1913	1.265e-82	278.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_1332669_5	344747.PM8797T_00262	2.109e-52	197.0	COG4974@1|root,COG4974@2|Bacteria,2IX6A@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_1332669_8	56110.Oscil6304_4430	3.671e-26	113.0	COG0616@1|root,COG0616@2|Bacteria,1G1AY@1117|Cyanobacteria,1H7U5@1150|Oscillatoriales	1117|Cyanobacteria	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_1336093_0	388401.RB2150_03289	2.934e-113	369.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,3ZGY7@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_1336093_2	1354722.JQLS01000008_gene2104	1.269e-75	257.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2U9MT@28211|Alphaproteobacteria,46NEE@74030|Roseovarius	28211|Alphaproteobacteria	Q	Related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_1336093_1	571166.KI421509_gene1736	2.083e-103	341.0	COG1802@1|root,COG1802@2|Bacteria,1MXNF@1224|Proteobacteria,2U1PK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Regulatory protein GntR HTH	MA20_15070	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_1336093_3	331869.BAL199_21019	9.133e-69	235.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,4BP68@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6,2.3.3.15	ko:K01652,ko:K03852	ko00290,ko00430,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00430,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R05651,R08648	RC00027,RC00106,RC01192,RC02744,RC02893,RC02903,RC02909	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_1349182_6	521674.Plim_3458	3.59e-15	81.0	COG0824@1|root,COG0824@2|Bacteria,2J02N@203682|Planctomycetes	203682|Planctomycetes	S	Thioesterase superfamily	-	-	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT
CMS1_k127_1349182_3	861299.J421_4511	2.137e-118	413.0	COG3693@1|root,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	xynA	-	3.2.1.37,3.2.1.55,3.2.1.8	ko:K01181,ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_10
CMS1_k127_1349182_1	1121957.ATVL01000008_gene4460	5.722e-193	632.0	COG3507@1|root,COG3507@2|Bacteria,4NEIZ@976|Bacteroidetes,47NFQ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS1_k127_1349182_0	1185876.BN8_00704	5.435e-256	797.0	COG3507@1|root,COG3507@2|Bacteria,4NEVJ@976|Bacteroidetes,47JBZ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM_6,Glyco_hydro_43
CMS1_k127_1349182_2	452637.Oter_1389	3.103e-141	474.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_1349182_5	452637.Oter_1388	3.443e-41	158.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
CMS1_k127_1349182_4	694427.Palpr_2118	6.848e-46	167.0	COG3664@1|root,COG3664@2|Bacteria,4NHQ0@976|Bacteroidetes,2FQ9R@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
CMS1_k127_1354237_6	382464.ABSI01000005_gene1150	1.763e-83	286.0	COG2211@1|root,COG2211@2|Bacteria,46UNF@74201|Verrucomicrobia,2IV5Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS1_k127_1354237_7	319795.Dgeo_2684	5.726e-67	258.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM_2,Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
CMS1_k127_1354237_3	452637.Oter_4322	3.552e-169	566.0	COG3507@1|root,COG3507@2|Bacteria,46U5E@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
CMS1_k127_1354237_8	794903.OPIT5_16915	6.532e-59	210.0	COG0463@1|root,COG0463@2|Bacteria,46VGP@74201|Verrucomicrobia,3K9GU@414999|Opitutae	414999|Opitutae	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254
CMS1_k127_1354237_9	760011.Spico_1397	5.544e-51	198.0	COG5184@1|root,COG5184@2|Bacteria,2J8DW@203691|Spirochaetes	203691|Spirochaetes	DZ	COGs COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Mfa_like_1,RCC1,RCC1_2
CMS1_k127_1354237_5	583355.Caka_1215	8.247e-107	361.0	COG0719@1|root,COG0719@2|Bacteria,46S8S@74201|Verrucomicrobia,3K7PW@414999|Opitutae	414999|Opitutae	O	FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_1354237_10	713587.THITH_05240	6.025e-45	173.0	28JZ9@1|root,2Z9PC@2|Bacteria,1R7GE@1224|Proteobacteria,1S7TF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1354237_1	1123070.KB899261_gene2126	6.481e-236	737.0	COG0719@1|root,COG0719@2|Bacteria,46SGN@74201|Verrucomicrobia,2IU30@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_1354237_4	382464.ABSI01000005_gene1099	1.294e-118	385.0	COG0396@1|root,COG0396@2|Bacteria,46SGE@74201|Verrucomicrobia,2ITY7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS1_k127_1354237_11	382464.ABSI01000005_gene1100	1.597e-33	134.0	COG0735@1|root,COG0735@2|Bacteria,46W8N@74201|Verrucomicrobia,2IUJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_1354237_2	243233.MCA0770	2.752e-217	687.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XE4Y@135618|Methylococcales	1236|Gammaproteobacteria	C	Glutamate synthase, NADH NADPH, small subunit	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4,Fer4_20,NAD_binding_1,Pyr_redox_2
CMS1_k127_1354237_0	880073.Calab_1547	0.0	1258.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ,iLF82_1304.LF82_2789,iNRG857_1313.NRG857_06920	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_1355291_13	264462.Bd1705	1.034e-18	89.0	COG2070@1|root,COG2070@2|Bacteria	2|Bacteria	S	nitronate monooxygenase activity	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS1_k127_1355291_7	583355.Caka_1191	1.827e-40	158.0	COG0558@1|root,COG0558@2|Bacteria,46VDE@74201|Verrucomicrobia,3K862@414999|Opitutae	414999|Opitutae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_1355291_9	583355.Caka_1190	3.439e-33	135.0	COG1267@1|root,COG1267@2|Bacteria,46VNU@74201|Verrucomicrobia,3K86I@414999|Opitutae	414999|Opitutae	I	Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CMS1_k127_1355291_1	382464.ABSI01000012_gene1959	8.708e-142	472.0	COG1086@1|root,COG1086@2|Bacteria,46UPP@74201|Verrucomicrobia,2IVCB@203494|Verrucomicrobiae	2|Bacteria	GM	Polysaccharide biosynthesis protein	capD	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	4.2.1.115,4.2.1.135,4.2.1.46	ko:K01710,ko:K15894,ko:K15912,ko:K19421	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
CMS1_k127_1355291_5	583355.Caka_1480	2.449e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,3K9TR@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1355291_14	583355.Caka_2439	2.256e-16	81.0	COG0238@1|root,COG0238@2|Bacteria,46ZDM@74201|Verrucomicrobia,3K8HR@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS18 family	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS1_k127_1355291_3	452637.Oter_1598	2.4e-99	335.0	COG0009@1|root,COG0009@2|Bacteria,46UW5@74201|Verrucomicrobia,3K7I8@414999|Opitutae	414999|Opitutae	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS1_k127_1355291_12	1396141.BATP01000051_gene3315	4.172e-20	106.0	2F4ED@1|root,33X4P@2|Bacteria,46VJA@74201|Verrucomicrobia,2IUYK@203494|Verrucomicrobiae	1396141.BATP01000051_gene3315|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1355291_2	583355.Caka_1470	1.112e-118	388.0	COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,3K7A4@414999|Opitutae	414999|Opitutae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
CMS1_k127_1355291_0	452637.Oter_4044	7.923e-158	518.0	COG0323@1|root,COG3170@1|root,COG0323@2|Bacteria,COG3170@2|Bacteria,46SG5@74201|Verrucomicrobia,3K76S@414999|Opitutae	414999|Opitutae	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_1355291_11	583355.Caka_2809	3.556e-25	107.0	COG0776@1|root,COG0776@2|Bacteria,46ZE7@74201|Verrucomicrobia,3K9SJ@414999|Opitutae	414999|Opitutae	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_1355291_4	583355.Caka_0701	2.964e-96	329.0	COG0153@1|root,COG0153@2|Bacteria,46V7W@74201|Verrucomicrobia,3K7TW@414999|Opitutae	414999|Opitutae	G	Belongs to the GHMP kinase family. GalK subfamily	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS1_k127_1355291_8	452637.Oter_2145	6.924e-37	148.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,3K80X@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
CMS1_k127_1355291_10	610130.Closa_1205	7.778e-26	111.0	2E5YB@1|root,330N1@2|Bacteria,1VEVQ@1239|Firmicutes,24RVC@186801|Clostridia,22313@1506553|Lachnoclostridium	186801|Clostridia	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
CMS1_k127_1355291_6	509191.AEDB02000094_gene4155	4.093e-43	164.0	COG1309@1|root,COG1309@2|Bacteria,1V44X@1239|Firmicutes,24HI1@186801|Clostridia,3WP5I@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1355291_15	1396418.BATQ01000098_gene5985	1.022e-09	61.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS1_k127_135822_3	455632.SGR_634	5.773e-64	225.0	COG5285@1|root,COG5285@2|Bacteria,2GM19@201174|Actinobacteria	201174|Actinobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_135822_4	794903.OPIT5_14750	5.761e-60	219.0	COG1063@1|root,COG1063@2|Bacteria,46Y69@74201|Verrucomicrobia,3K90B@414999|Opitutae	414999|Opitutae	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_135822_2	65093.PCC7418_1233	1.12e-67	249.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1GQEJ@1117|Cyanobacteria	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_135822_6	1246995.AFR_17360	1.596e-24	115.0	COG0673@1|root,COG0673@2|Bacteria,2IFZE@201174|Actinobacteria,4DHQ3@85008|Micromonosporales	201174|Actinobacteria	S	Putative oxidoreductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,ox_reductase_C
CMS1_k127_135822_0	366602.Caul_4930	2.906e-117	387.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,2KG7A@204458|Caulobacterales	204458|Caulobacterales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_135822_1	234267.Acid_3405	2.034e-101	346.0	COG2303@1|root,COG2303@2|Bacteria,3Y6FS@57723|Acidobacteria	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_1359523_1	583355.Caka_0417	2.243e-76	264.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46TZV@74201|Verrucomicrobia,3K897@414999|Opitutae	414999|Opitutae	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
CMS1_k127_1359523_3	1224136.AMFN01000005_gene1204	4.343e-32	138.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	general secretion pathway protein	gspF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_1359523_2	452637.Oter_2690	3.78e-70	248.0	COG1561@1|root,COG1561@2|Bacteria,46V58@74201|Verrucomicrobia,3K7K3@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS1_k127_1359523_0	382464.ABSI01000021_gene413	3.213e-87	292.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_1410991_2	583355.Caka_2442	2.845e-55	202.0	COG1729@1|root,COG1729@2|Bacteria,46TWU@74201|Verrucomicrobia,3K7AZ@414999|Opitutae	414999|Opitutae	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS1_k127_1410991_1	452637.Oter_0242	3.304e-61	218.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_1410991_3	452637.Oter_0241	1.261e-05	54.0	COG0848@1|root,COG0848@2|Bacteria,46XVE@74201|Verrucomicrobia,3K8DN@414999|Opitutae	414999|Opitutae	U	biopolymer transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1410991_0	583355.Caka_1758	7.043e-216	680.0	COG1233@1|root,COG1233@2|Bacteria,46YTW@74201|Verrucomicrobia,3K7V6@414999|Opitutae	414999|Opitutae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS1_k127_1468749_3	1396141.BATP01000030_gene3700	1.211e-29	122.0	COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,2ITQT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase family M3	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS1_k127_1468749_2	243233.MCA2713	8.573e-77	270.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1XDTX@135618|Methylococcales	135618|Methylococcales	M	family 9	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_1468749_1	983917.RGE_13810	2.571e-105	357.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,1KMCE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1468749_4	1396418.BATQ01000053_gene36	9.257e-16	90.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia,2IUNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_9,Lip_A_acyltrans
CMS1_k127_1468749_0	420324.KI912031_gene2928	5.751e-131	424.0	COG1633@1|root,COG1633@2|Bacteria,1MUET@1224|Proteobacteria,2TQMZ@28211|Alphaproteobacteria,1JU9D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Rubrerythrin	MA20_19235	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_1484542_1	452637.Oter_3831	1.109e-16	93.0	COG1639@1|root,COG3437@1|root,COG1639@2|Bacteria,COG3437@2|Bacteria,46U1Q@74201|Verrucomicrobia,3K7GB@414999|Opitutae	414999|Opitutae	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS1_k127_1484542_0	1403819.BATR01000052_gene1576	4.644e-25	114.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia,2IUP1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS1_k127_1484542_2	1121100.JCM6294_2476	3.955e-08	58.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia,4AM5X@815|Bacteroidaceae	976|Bacteroidetes	S	Von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS1_k127_1496688_1	572479.Hprae_1070	7.627e-59	209.0	COG1787@1|root,COG1787@2|Bacteria	2|Bacteria	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	ATP-cone,Mrr_cat
CMS1_k127_1496688_2	159450.NH14_14870	1.941e-26	117.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VQAN@28216|Betaproteobacteria,1K2GS@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_1496688_0	338966.Ppro_2598	7.594e-85	305.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,43U7B@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase A domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
CMS1_k127_1520759_1	994573.T472_0209620	3.16e-26	117.0	COG2159@1|root,COG2159@2|Bacteria,1W49D@1239|Firmicutes,254HV@186801|Clostridia	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_1520759_0	583355.Caka_1844	5.969e-103	346.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,46S4N@74201|Verrucomicrobia,3K7B9@414999|Opitutae	414999|Opitutae	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS1_k127_1542146_2	794903.OPIT5_18610	9.556e-116	386.0	COG0507@1|root,COG0507@2|Bacteria,46U9H@74201|Verrucomicrobia,3K7J4@414999|Opitutae	414999|Opitutae	L	AAA ATPase	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS1_k127_1542146_6	931626.Awo_c06280	6.612e-12	71.0	arCOG03368@1|root,331XD@2|Bacteria,1VHY0@1239|Firmicutes,24SSZ@186801|Clostridia,25ZA7@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1542146_0	448385.sce6460	0.0	1169.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
CMS1_k127_1542146_1	1144275.COCOR_01696	3.588e-137	448.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2Z30B@29|Myxococcales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
CMS1_k127_1542146_4	583355.Caka_2771	3.058e-34	141.0	COG2165@1|root,COG2165@2|Bacteria,46WCD@74201|Verrucomicrobia,3K8AN@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_1542146_3	583355.Caka_2653	6.616e-112	374.0	COG0604@1|root,COG0604@2|Bacteria,46VF4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
CMS1_k127_1542146_5	452637.Oter_2446	2.413e-29	124.0	COG0262@1|root,COG0262@2|Bacteria,46X6E@74201|Verrucomicrobia,3K9WI@414999|Opitutae	414999|Opitutae	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
CMS1_k127_1550596_1	583355.Caka_0911	1.073e-29	130.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia,3K75N@414999|Opitutae	414999|Opitutae	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_1550596_0	926561.KB900617_gene1249	1.537e-188	611.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WAES@53433|Halanaerobiales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS1_k127_157018_2	583355.Caka_0267	4.289e-27	111.0	COG0353@1|root,COG0353@2|Bacteria,46SU3@74201|Verrucomicrobia,3K72H@414999|Opitutae	414999|Opitutae	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim,Toprim_4
CMS1_k127_157018_0	382464.ABSI01000012_gene2128	1.379e-38	152.0	COG0494@1|root,COG0494@2|Bacteria,46ZKB@74201|Verrucomicrobia,2IUIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_157018_1	583355.Caka_1892	7.511e-30	120.0	COG0361@1|root,COG0361@2|Bacteria,46ZFZ@74201|Verrucomicrobia,3K8AU@414999|Opitutae	414999|Opitutae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_157018_3	452637.Oter_3747	3.775e-07	54.0	COG4284@1|root,COG4284@2|Bacteria,46U9U@74201|Verrucomicrobia,3K7T1@414999|Opitutae	414999|Opitutae	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.23,2.7.7.64,2.7.7.83	ko:K00972,ko:K12447	ko00040,ko00052,ko00053,ko00520,ko01100,ko01130,map00040,map00052,map00053,map00520,map01100,map01130	M00014,M00361,M00362	R00289,R00416,R00502,R01381,R03077,R08845	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS1_k127_1570950_1	596151.DesfrDRAFT_1984	6.11e-82	286.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg,dCache_1
CMS1_k127_1570950_0	382464.ABSI01000011_gene2838	3.575e-105	364.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
CMS1_k127_1570950_2	583355.Caka_1567	4.478e-48	174.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,3K7DX@414999|Opitutae	414999|Opitutae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_1575550_0	382464.ABSI01000014_gene1422	0.0	1281.0	COG0209@1|root,COG0209@2|Bacteria,46SFJ@74201|Verrucomicrobia,2ITXA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Ribonucleotide reductase, all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_1575550_2	583355.Caka_1437	1.332e-55	201.0	COG0632@1|root,COG0632@2|Bacteria,46VFW@74201|Verrucomicrobia,3K80K@414999|Opitutae	414999|Opitutae	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS1_k127_1575550_1	655815.ZPR_3478	1.287e-123	410.0	COG3934@1|root,COG3934@2|Bacteria,4NJJS@976|Bacteroidetes	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,DUF5060
CMS1_k127_1596198_11	408672.NBCG_03483	0.0001548	46.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DP9T@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS1_k127_1596198_6	1201290.M902_3288	2.878e-26	121.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2MT0Z@213481|Bdellovibrionales,2WMRQ@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS1_k127_1596198_0	583355.Caka_1071	4.28e-239	752.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,3K7KC@414999|Opitutae	414999|Opitutae	H	acetolactate synthase large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_1596198_12	1245469.S58_21800	0.0006635	52.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2TU29@28211|Alphaproteobacteria,3JQN5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	HEAT repeat	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS1_k127_1596198_2	388467.A19Y_2622	3.988e-78	276.0	COG0476@1|root,COG0476@2|Bacteria,1GA75@1117|Cyanobacteria	1117|Cyanobacteria	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
CMS1_k127_1596198_7	388467.A19Y_2623	1.036e-22	102.0	2E4CS@1|root,32Z87@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1596198_4	1117647.M5M_00830	9.145e-51	192.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1JA3N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_1596198_3	1042377.AFPJ01000051_gene33	2.205e-51	193.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_1596198_9	382464.ABSI01000002_gene4270	5.351e-09	64.0	COG0810@1|root,COG0810@2|Bacteria,46WU9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS1_k127_1596198_8	452637.Oter_3842	1.588e-12	73.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_C
CMS1_k127_1596198_5	278957.ABEA03000180_gene1996	1.084e-45	189.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia,3K9B6@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
CMS1_k127_1596198_1	1396141.BATP01000022_gene422	5.087e-146	470.0	COG0034@1|root,COG0034@2|Bacteria,46UKZ@74201|Verrucomicrobia,2ITSB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	-
CMS1_k127_1622522_3	794903.OPIT5_30215	4.753e-13	72.0	COG0848@1|root,COG0848@2|Bacteria,46W74@74201|Verrucomicrobia,3K9FM@414999|Opitutae	414999|Opitutae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_1622522_2	452637.Oter_2346	2.722e-30	124.0	COG0848@1|root,COG0848@2|Bacteria,46W74@74201|Verrucomicrobia,3K87N@414999|Opitutae	414999|Opitutae	U	Biopolymer transportern ExbD	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_1622522_1	794903.OPIT5_30210	1.286e-57	207.0	COG0811@1|root,COG0811@2|Bacteria,46VCM@74201|Verrucomicrobia,3K7V1@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_1622522_0	1184609.KILIM_060_00090	1.89e-151	489.0	COG1883@1|root,COG1883@2|Bacteria,2IF5V@201174|Actinobacteria,4F72A@85018|Dermatophilaceae	201174|Actinobacteria	C	Na+-transporting oxaloacetate decarboxylase beta subunit	mmdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
CMS1_k127_1634994_3	56780.SYN_01373	4.766e-16	84.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R6F@68525|delta/epsilon subdivisions,2WN2B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
CMS1_k127_1634994_1	278957.ABEA03000075_gene2314	1.492e-87	300.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia,3K744@414999|Opitutae	414999|Opitutae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS1_k127_1634994_0	76114.ebA5654	5.244e-89	303.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,2KVAJ@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1634994_2	1502724.FF80_04029	1.282e-50	185.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
CMS1_k127_1634995_1	357808.RoseRS_2225	6.075e-57	203.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	catD	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,SnoaL_2
CMS1_k127_1634995_0	1463885.KL578451_gene8091	4.125e-64	228.0	COG3473@1|root,COG3473@2|Bacteria	2|Bacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
CMS1_k127_1634995_2	1123237.Salmuc_01361	2.831e-45	166.0	COG1541@1|root,COG1541@2|Bacteria,1P22K@1224|Proteobacteria	1224|Proteobacteria	H	coenzyme F390 synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CMS1_k127_1641187_1	240015.ACP_1265	6.343e-99	333.0	COG2272@1|root,COG2272@2|Bacteria,3Y2GS@57723|Acidobacteria,2JKJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS1_k127_1641187_0	382464.ABSI01000021_gene419	9.491e-212	668.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_1644419_5	240015.ACP_1265	1.382e-48	179.0	COG2272@1|root,COG2272@2|Bacteria,3Y2GS@57723|Acidobacteria,2JKJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS1_k127_1644419_6	706587.Desti_0455	1.582e-41	160.0	COG0789@1|root,COG0789@2|Bacteria,1MWN0@1224|Proteobacteria,42U2V@68525|delta/epsilon subdivisions,2WQJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
CMS1_k127_1644419_7	994573.T472_0215665	2.39e-25	111.0	2E69N@1|root,32VUZ@2|Bacteria,1VP5P@1239|Firmicutes,24UF1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1644419_11	1156937.MFUM_140023	8.44e-14	74.0	COG2331@1|root,COG2331@2|Bacteria,46T5Z@74201|Verrucomicrobia,37H04@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1644419_4	583355.Caka_2819	2.048e-68	238.0	COG0663@1|root,COG0663@2|Bacteria,46V13@74201|Verrucomicrobia,3K82W@414999|Opitutae	414999|Opitutae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_1644419_3	573061.Clocel_0442	3.805e-84	287.0	COG0693@1|root,COG0693@2|Bacteria,1UDUN@1239|Firmicutes,24Y5U@186801|Clostridia,36U4E@31979|Clostridiaceae	2|Bacteria	S	PFAM ThiJ PfpI domain-containing protein	-	-	3.5.1.124	ko:K03152,ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI,ThiJ_like
CMS1_k127_1644419_10	1443665.JACA01000051_gene1998	1.66e-15	83.0	COG2839@1|root,COG2839@2|Bacteria,4NP3I@976|Bacteroidetes,1IMGE@117743|Flavobacteriia,2YGHE@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
CMS1_k127_1644419_1	278957.ABEA03000143_gene1053	2.781e-108	361.0	COG0337@1|root,COG0337@2|Bacteria,46SRE@74201|Verrucomicrobia,3K7IX@414999|Opitutae	414999|Opitutae	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS1_k127_1644419_0	794903.OPIT5_21475	8.517e-177	559.0	COG0473@1|root,COG0473@2|Bacteria,46TRZ@74201|Verrucomicrobia,3K7FD@414999|Opitutae	414999|Opitutae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_1644419_12	1244531.CIG1485E_0927	0.0005002	48.0	2AIWU@1|root,319EF@2|Bacteria,1Q2HR@1224|Proteobacteria,42VR2@68525|delta/epsilon subdivisions,2YQN9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
CMS1_k127_1644419_2	1122962.AULH01000013_gene531	2.024e-97	332.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,36ZY1@31993|Methylocystaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
CMS1_k127_1644419_8	402777.KB235904_gene4269	4.902e-25	118.0	COG0438@1|root,COG1196@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1196@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1FZUY@1117|Cyanobacteria,1H86A@1150|Oscillatoriales	1117|Cyanobacteria	DM	Glycosyl transferase, group	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_31,Sulfotransfer_3
CMS1_k127_1650258_1	1209072.ALBT01000007_gene2793	1.467e-239	811.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1FHSS@10|Cellvibrio	1236|Gammaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS1_k127_1650258_0	215803.DB30_8592	0.0	1263.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,43BZC@68525|delta/epsilon subdivisions,2X7A3@28221|Deltaproteobacteria,2YWPR@29|Myxococcales	28221|Deltaproteobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt
CMS1_k127_1650258_2	1249627.D779_0239	2.813e-95	323.0	COG0330@1|root,COG0330@2|Bacteria,1RDFI@1224|Proteobacteria,1S655@1236|Gammaproteobacteria,1X0UN@135613|Chromatiales	135613|Chromatiales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_1650258_3	497965.Cyan7822_2422	2.134e-35	150.0	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria,3KJ4J@43988|Cyanothece	1117|Cyanobacteria	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CMS1_k127_1650258_4	349521.HCH_02804	3.207e-21	100.0	COG4615@1|root,COG4615@2|Bacteria,1MVIC@1224|Proteobacteria,1RMYK@1236|Gammaproteobacteria,1XI58@135619|Oceanospirillales	135619|Oceanospirillales	V	Cyclic peptide transporter	yojI	-	-	ko:K06159,ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2,3.A.1.113.3	-	-	ABC_membrane,ABC_tran
CMS1_k127_1651409_1	278957.ABEA03000094_gene4753	2.063e-63	240.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46TWU@74201|Verrucomicrobia,3K7AZ@414999|Opitutae	414999|Opitutae	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS1_k127_1651409_0	452637.Oter_0658	0.0	1031.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia,3K74R@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_1651409_2	583355.Caka_0695	2.465e-26	108.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_165615_0	583355.Caka_2613	8.227e-139	454.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia,3K7NE@414999|Opitutae	414999|Opitutae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_165615_1	794903.OPIT5_17240	2.924e-51	193.0	COG0144@1|root,COG0144@2|Bacteria,46V5S@74201|Verrucomicrobia,3K7YH@414999|Opitutae	414999|Opitutae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
CMS1_k127_1697257_6	155864.EDL933_3230	2.371e-34	145.0	COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	Belongs to the peptidase S14 family	clpP_2	-	-	-	-	-	-	-	-	-	-	-	CLP_protease,Mu-like_gpT
CMS1_k127_1697257_5	1031288.AXAA01000048_gene768	6.571e-37	152.0	2BZ9Z@1|root,2Z97E@2|Bacteria,1U6NR@1239|Firmicutes,24FZN@186801|Clostridia,36GJA@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1697257_1	382464.ABSI01000005_gene1187	4.808e-83	284.0	COG2003@1|root,COG2003@2|Bacteria,46STQ@74201|Verrucomicrobia,2IU7T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_1697257_7	643867.Ftrac_1694	2.674e-34	138.0	COG1309@1|root,COG1309@2|Bacteria,4NMW1@976|Bacteroidetes,47Q10@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1697257_3	1122180.Lokhon_00224	6.243e-64	230.0	COG4221@1|root,COG4221@2|Bacteria,1PF3F@1224|Proteobacteria,2V7QR@28211|Alphaproteobacteria,2PA01@245186|Loktanella	28211|Alphaproteobacteria	C	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1697257_9	1278073.MYSTI_07910	4.079e-12	75.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	ymjC	-	1.1.1.219,1.1.1.271,1.3.1.75,1.6.5.2,2.7.9.2	ko:K00091,ko:K01007,ko:K02377,ko:K07118,ko:K19073,ko:K19267	ko00051,ko00130,ko00520,ko00620,ko00680,ko00720,ko00860,ko01100,ko01110,ko01120,ko01200,map00051,map00130,map00520,map00620,map00680,map00720,map00860,map01100,map01110,map01120,map01200	M00173,M00374	R00199,R02964,R03643,R03816,R05692,R06272,R06896	RC00002,RC00015,RC00819,RC01014,RC01376	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_1697257_2	1304874.JAFY01000001_gene2638	3.064e-66	233.0	COG0655@1|root,COG0655@2|Bacteria,3TBAN@508458|Synergistetes	508458|Synergistetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CMS1_k127_1697257_4	32057.KB217478_gene4578	2.566e-37	145.0	COG4994@1|root,COG4994@2|Bacteria,1G6FZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS1_k127_1697257_0	583355.Caka_1148	7.691e-191	619.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,3K7BP@414999|Opitutae	414999|Opitutae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
CMS1_k127_1697257_10	794903.OPIT5_24985	2.552e-11	71.0	2FIUS@1|root,34AK6@2|Bacteria,46WE9@74201|Verrucomicrobia,3K8CJ@414999|Opitutae	414999|Opitutae	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
CMS1_k127_1697257_8	382464.ABSI01000016_gene727	4.397e-18	97.0	COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,46UTQ@74201|Verrucomicrobia	74201|Verrucomicrobia	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS1_k127_1739545_1	1125863.JAFN01000001_gene2883	1.509e-33	136.0	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_1739545_2	398767.Glov_3310	0.0002588	50.0	COG1406@1|root,COG1406@2|Bacteria,1N38Q@1224|Proteobacteria,42UIA@68525|delta/epsilon subdivisions,2WQV5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	cheX64H	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
CMS1_k127_1739545_0	583355.Caka_1844	9.421e-185	594.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,46S4N@74201|Verrucomicrobia,3K7B9@414999|Opitutae	414999|Opitutae	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS1_k127_1739669_4	452637.Oter_2048	1.712e-168	552.0	COG4774@1|root,COG4774@2|Bacteria	452637.Oter_2048|-	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1739669_3	452637.Oter_2049	1.515e-199	632.0	COG2211@1|root,COG2211@2|Bacteria,46YMU@74201|Verrucomicrobia,3K7KX@414999|Opitutae	414999|Opitutae	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS1_k127_1739669_5	382464.ABSI01000018_gene109	3.742e-146	470.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_1739669_0	452637.Oter_2051	5.296e-261	824.0	COG3250@1|root,COG3250@2|Bacteria,46UWF@74201|Verrucomicrobia,3K7BB@414999|Opitutae	2|Bacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_1739669_7	1396141.BATP01000032_gene4337	1.143e-39	154.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
CMS1_k127_1739669_1	794903.OPIT5_05875	1.673e-254	791.0	COG0753@1|root,COG0753@2|Bacteria,46TCG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalase	-	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
CMS1_k127_1739669_6	697282.Mettu_3441	1.968e-40	158.0	COG0454@1|root,COG0456@2|Bacteria,1PGN9@1224|Proteobacteria,1TC1D@1236|Gammaproteobacteria,1XFA9@135618|Methylococcales	135618|Methylococcales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1739669_2	382464.ABSI01000021_gene411	1.147e-203	647.0	COG3604@1|root,COG3604@2|Bacteria,46YU4@74201|Verrucomicrobia,2IVAR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_1740206_1	583355.Caka_1236	1.878e-69	241.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia,3K8BT@414999|Opitutae	414999|Opitutae	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_1740206_0	583355.Caka_2711	0.0	1534.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,3K7EI@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_178090_1	452637.Oter_0143	2.743e-173	581.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS1_k127_178090_2	1122194.AUHU01000010_gene3138	4.506e-158	520.0	COG1409@1|root,COG1409@2|Bacteria,1NI34@1224|Proteobacteria,1S397@1236|Gammaproteobacteria,46AR6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_178090_5	1123020.AUIE01000026_gene4930	2.435e-05	51.0	COG3568@1|root,COG3568@2|Bacteria,1RJX3@1224|Proteobacteria,1S7J9@1236|Gammaproteobacteria,1YFJU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_178090_0	452637.Oter_2927	4.352e-260	820.0	COG4585@1|root,COG4585@2|Bacteria,46SBM@74201|Verrucomicrobia,3K8FJ@414999|Opitutae	414999|Opitutae	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS1_k127_178090_3	382464.ABSI01000017_gene71	1.966e-101	334.0	COG2197@1|root,COG2197@2|Bacteria,46V6C@74201|Verrucomicrobia,2IUHI@203494|Verrucomicrobiae	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_178090_4	583355.Caka_1097	1.811e-19	97.0	COG0760@1|root,COG0760@2|Bacteria,46T1I@74201|Verrucomicrobia,3K7JC@414999|Opitutae	414999|Opitutae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
CMS1_k127_1785572_2	382464.ABSI01000012_gene2239	4.599e-42	174.0	COG0784@1|root,COG2208@1|root,COG0784@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF4388,PAS,PAS_9,Response_reg,SpoIIE
CMS1_k127_1785572_0	794903.OPIT5_20765	1.275e-168	542.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia,3K7JM@414999|Opitutae	414999|Opitutae	M	Mur ligase	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_1785572_1	1304885.AUEY01000005_gene891	2.053e-103	344.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7Z@28221|Deltaproteobacteria,2MPT3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
CMS1_k127_1785572_3	794903.OPIT5_16435	3.092e-10	62.0	2AX8K@1|root,31P7E@2|Bacteria,46XUD@74201|Verrucomicrobia,3K874@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1794800_3	743720.Psefu_1780	0.0002551	49.0	2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria	1224|Proteobacteria	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
CMS1_k127_1794800_0	583355.Caka_2326	2.033e-204	650.0	COG0166@1|root,COG0166@2|Bacteria,46SUH@74201|Verrucomicrobia,3K7K9@414999|Opitutae	414999|Opitutae	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS1_k127_1794800_1	794903.OPIT5_15595	1.102e-76	265.0	COG0313@1|root,COG0313@2|Bacteria,46SVC@74201|Verrucomicrobia,3K7C1@414999|Opitutae	414999|Opitutae	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS1_k127_1794800_2	583355.Caka_1789	2.59e-58	214.0	COG0248@1|root,COG0248@2|Bacteria,46T7T@74201|Verrucomicrobia,3K7WZ@414999|Opitutae	414999|Opitutae	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS1_k127_1804410_6	1295642.H839_04584	1.565e-56	204.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1WFSN@129337|Geobacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_1804410_2	452637.Oter_0394	7.658e-129	421.0	COG1706@1|root,COG1706@2|Bacteria,46TDB@74201|Verrucomicrobia,3K78D@414999|Opitutae	414999|Opitutae	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
CMS1_k127_1804410_8	452637.Oter_0395	1.912e-34	139.0	COG2063@1|root,COG2063@2|Bacteria,46VP3@74201|Verrucomicrobia,3K818@414999|Opitutae	414999|Opitutae	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
CMS1_k127_1804410_11	1301098.PKB_2547	2.854e-08	64.0	COG1261@1|root,COG1261@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	flgA	-	-	ko:K02279,ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	ChapFlgA,SAF
CMS1_k127_1804410_4	452637.Oter_0397	3.619e-90	306.0	COG4786@1|root,COG4786@2|Bacteria,46UIV@74201|Verrucomicrobia,3K75R@414999|Opitutae	414999|Opitutae	N	Flagella basal body rod protein	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS1_k127_1804410_7	452637.Oter_0398	1.184e-41	163.0	COG4786@1|root,COG4786@2|Bacteria,46VRG@74201|Verrucomicrobia,3K81G@414999|Opitutae	414999|Opitutae	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Flg_bbr_C
CMS1_k127_1804410_0	382464.ABSI01000010_gene3243	3.096e-310	974.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia,2ITV9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of unknown function (DUF3516)	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
CMS1_k127_1804410_3	452637.Oter_1554	1.229e-97	334.0	COG1538@1|root,COG1538@2|Bacteria,46WHQ@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_1804410_1	452637.Oter_4431	4.067e-148	482.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,3K8NI@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
CMS1_k127_1804410_5	452637.Oter_4432	3.26e-80	273.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia,3K7EV@414999|Opitutae	414999|Opitutae	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS1_k127_1805387_1	234267.Acid_3588	1.67e-63	226.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria	57723|Acidobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_1805387_0	452637.Oter_4012	3.582e-97	332.0	COG0438@1|root,COG0438@2|Bacteria,46V09@74201|Verrucomicrobia,3K7MD@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_1805387_2	452637.Oter_4013	6.478e-35	139.0	COG0707@1|root,COG0707@2|Bacteria,46UKT@74201|Verrucomicrobia,3K85S@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C
CMS1_k127_1828291_0	583355.Caka_1787	8.792e-164	532.0	COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,3K7PG@414999|Opitutae	414999|Opitutae	IQ	AMP-dependent synthetase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
CMS1_k127_1835475_1	877455.Metbo_1105	0.000478	52.0	arCOG06693@1|root,arCOG06693@2157|Archaea,2Y20U@28890|Euryarchaeota	28890|Euryarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1835475_0	1191523.MROS_0925	8.891e-70	245.0	COG0038@1|root,COG0517@1|root,COG3273@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	ko:K03281,ko:K03455,ko:K07085,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.37,2.A.49,2.A.81	-	-	CBS,Ion_trans_2,Na_H_Exchanger,TrkA_C,TrkA_N,Voltage_CLC
CMS1_k127_1839051_3	583355.Caka_2600	3.063e-55	201.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,3K83M@414999|Opitutae	414999|Opitutae	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_1839051_0	583355.Caka_2599	1.541e-191	612.0	COG0111@1|root,COG0111@2|Bacteria,46Z6K@74201|Verrucomicrobia	74201|Verrucomicrobia	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS1_k127_1839051_1	382464.ABSI01000017_gene47	1.984e-158	520.0	COG3693@1|root,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
CMS1_k127_1839051_2	411462.DORLON_01173	2.046e-96	321.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,27UZY@189330|Dorea	186801|Clostridia	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_1839051_4	452637.Oter_4516	2.369e-31	130.0	COG2819@1|root,COG2819@2|Bacteria,46W78@74201|Verrucomicrobia,3K9WA@414999|Opitutae	414999|Opitutae	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
CMS1_k127_1858261_0	583355.Caka_1071	1.418e-249	782.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,3K7KC@414999|Opitutae	414999|Opitutae	H	acetolactate synthase large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_1858261_2	452637.Oter_2680	1.191e-233	733.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia,3K7KT@414999|Opitutae	414999|Opitutae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS1_k127_1858261_5	452637.Oter_2385	1.204e-38	147.0	COG1694@1|root,COG1694@2|Bacteria,46W6C@74201|Verrucomicrobia,3K875@414999|Opitutae	414999|Opitutae	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CMS1_k127_1858261_3	583355.Caka_1537	2.695e-101	342.0	COG1253@1|root,COG1253@2|Bacteria,46UX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
CMS1_k127_1858261_4	404380.Gbem_3742	1.057e-68	257.0	COG3914@1|root,COG3914@2|Bacteria,1QU3U@1224|Proteobacteria,43CQC@68525|delta/epsilon subdivisions,2X7XP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
CMS1_k127_1858261_1	794903.OPIT5_26110	2.244e-249	788.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,3K75C@414999|Opitutae	414999|Opitutae	L	Helicase associated domain (HA2)  Add an annotation	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
CMS1_k127_1890647_0	998674.ATTE01000001_gene77	4.004e-61	241.0	COG4457@1|root,COG4457@2|Bacteria,1MVRQ@1224|Proteobacteria,1RPSQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Virulence	srfB	-	-	-	-	-	-	-	-	-	-	-	SrfB
CMS1_k127_1924661_6	583355.Caka_1305	1.092e-29	121.0	COG1544@1|root,COG1544@2|Bacteria,46WAP@74201|Verrucomicrobia,3K89Z@414999|Opitutae	414999|Opitutae	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS1_k127_1924661_3	583355.Caka_1304	3.422e-68	242.0	COG0300@1|root,COG0300@2|Bacteria,46V22@74201|Verrucomicrobia,3K81R@414999|Opitutae	414999|Opitutae	S	short-chain dehydrogenase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS1_k127_1924661_1	583355.Caka_1303	3.046e-80	276.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,3K828@414999|Opitutae	414999|Opitutae	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS1_k127_1924661_4	667015.Bacsa_3020	3.875e-60	214.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,2FMA4@200643|Bacteroidia,4ANMW@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS1_k127_1924661_0	1410613.JNKF01000011_gene1141	3.44e-183	591.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,2FQHN@200643|Bacteroidia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	malL	-	3.2.1.1,3.2.1.10,3.2.1.20,5.4.99.16	ko:K01182,ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R01718,R01791,R02108,R02112,R06087,R06088,R06199,R11262	RC00028,RC00049,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
CMS1_k127_1924661_2	452637.Oter_4017	3.428e-76	272.0	COG0438@1|root,COG0438@2|Bacteria,46TX1@74201|Verrucomicrobia,3K93H@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1924661_5	794903.OPIT5_15215	4.611e-31	130.0	COG0300@1|root,COG0300@2|Bacteria,46VV4@74201|Verrucomicrobia,3K7WJ@414999|Opitutae	414999|Opitutae	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_193159_2	43989.cce_0523	1.047e-29	137.0	2EWXB@1|root,33Q8Q@2|Bacteria,1GBP2@1117|Cyanobacteria,3KJC6@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_193159_0	583355.Caka_2974	7.194e-150	493.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia,3K7KZ@414999|Opitutae	414999|Opitutae	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CMS1_k127_193159_1	1089545.KB913037_gene5092	3.388e-35	142.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.102,3.1.3.104	ko:K07025,ko:K20860	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
CMS1_k127_193159_3	715451.ambt_10780	9.003e-13	78.0	COG4773@1|root,COG4773@2|Bacteria,1NXPR@1224|Proteobacteria,1RSBC@1236|Gammaproteobacteria,466AC@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_1959860_10	641112.ACOK01000119_gene1470	3.004e-24	108.0	COG0454@1|root,COG0456@2|Bacteria,1V4QC@1239|Firmicutes,24J5M@186801|Clostridia,3WK6Y@541000|Ruminococcaceae	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS1_k127_1959860_6	382464.ABSI01000010_gene3574	1.61e-77	267.0	COG1212@1|root,COG1212@2|Bacteria,46SS4@74201|Verrucomicrobia,2IU4F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS1_k127_1959860_2	1396141.BATP01000039_gene1283	3.64e-138	452.0	COG2265@1|root,COG2265@2|Bacteria,46SYJ@74201|Verrucomicrobia,2ITST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS1_k127_1959860_5	335543.Sfum_1657	2.371e-86	295.0	COG0598@1|root,COG0598@2|Bacteria,1RGGI@1224|Proteobacteria,42UX4@68525|delta/epsilon subdivisions,2WQYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Mg2 transporter protein CorA family protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS1_k127_1959860_4	1396141.BATP01000017_gene2765	1.439e-86	297.0	COG0688@1|root,COG0688@2|Bacteria,46TND@74201|Verrucomicrobia,2ITXF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS1_k127_1959860_9	1403819.BATR01000171_gene5846	4.987e-37	151.0	COG0637@1|root,COG0637@2|Bacteria,46VM3@74201|Verrucomicrobia,2IUCI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_1959860_7	28564.XP_002339929.1	5.417e-49	193.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NW9Q@4751|Fungi,3QJDH@4890|Ascomycota,20AHF@147545|Eurotiomycetes,3S8DS@5042|Eurotiales	4751|Fungi	M	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,NACHT,PNP_UDP_1
CMS1_k127_1959860_0	382464.ABSI01000010_gene3399	1.189e-268	852.0	COG0550@1|root,COG0550@2|Bacteria,46S97@74201|Verrucomicrobia,2ITTZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
CMS1_k127_1959860_1	452637.Oter_3000	1.091e-140	456.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,3K7QY@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_1959860_8	583355.Caka_2406	6.369e-42	158.0	COG0853@1|root,COG0853@2|Bacteria,46XCB@74201|Verrucomicrobia,3K8EI@414999|Opitutae	414999|Opitutae	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS1_k127_1959860_3	794903.OPIT5_07775	7.172e-134	441.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,3K7KP@414999|Opitutae	414999|Opitutae	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS1_k127_1975810_0	1123242.JH636434_gene3703	2.825e-221	694.0	arCOG10801@1|root,2Z9IC@2|Bacteria,2J23R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1978846_1	583355.Caka_2817	2.363e-170	554.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_1978846_5	583355.Caka_1903	1.744e-35	140.0	COG0764@1|root,COG0764@2|Bacteria,46VX8@74201|Verrucomicrobia,3K8BA@414999|Opitutae	414999|Opitutae	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_1978846_2	382464.ABSI01000005_gene1339	9.064e-142	454.0	COG0175@1|root,COG0175@2|Bacteria,46TUQ@74201|Verrucomicrobia,2ITQ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS1_k127_1978846_0	153721.MYP_1245	4.973e-177	563.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
CMS1_k127_1978846_6	1304872.JAGC01000009_gene1212	9.716e-28	121.0	COG0500@1|root,COG2226@2|Bacteria,1PZ7S@1224|Proteobacteria,43EB8@68525|delta/epsilon subdivisions,2X07T@28221|Deltaproteobacteria,2MB47@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1978846_3	926550.CLDAP_36750	1.17e-58	217.0	COG3214@1|root,COG3214@2|Bacteria,2G766@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
CMS1_k127_1978846_4	794903.OPIT5_18295	5.855e-57	203.0	COG1249@1|root,COG1249@2|Bacteria,46SJE@74201|Verrucomicrobia,3K7MT@414999|Opitutae	414999|Opitutae	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_2033326_12	1211114.ALIP01000044_gene1997	1.394e-22	99.0	COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,1RQ0J@1236|Gammaproteobacteria,1X5D7@135614|Xanthomonadales	135614|Xanthomonadales	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CMS1_k127_2033326_10	97139.C824_02682	6.287e-41	160.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,36JHH@31979|Clostridiaceae	186801|Clostridia	G	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
CMS1_k127_2033326_13	382464.ABSI01000010_gene3288	5.744e-22	96.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS1_k127_2033326_7	583355.Caka_0905	2.489e-68	241.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_2033326_6	278957.ABEA03000106_gene1850	3.119e-88	307.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia,3K7UN@414999|Opitutae	414999|Opitutae	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S26
CMS1_k127_2033326_0	583355.Caka_0762	1.488e-286	890.0	COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia,3K7NB@414999|Opitutae	414999|Opitutae	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS1_k127_2033326_8	316273.XCV0629	1.904e-59	212.0	COG4977@1|root,COG4977@2|Bacteria,1QU10@1224|Proteobacteria,1T1KF@1236|Gammaproteobacteria,1XAXV@135614|Xanthomonadales	135614|Xanthomonadales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS1_k127_2033326_4	278957.ABEA03000041_gene2247	3.948e-96	323.0	COG0331@1|root,COG0331@2|Bacteria,46TH5@74201|Verrucomicrobia,3K7U9@414999|Opitutae	414999|Opitutae	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS1_k127_2033326_11	583355.Caka_2449	4.075e-27	116.0	COG0254@1|root,COG0254@2|Bacteria,46XUU@74201|Verrucomicrobia,3K8B9@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL31 family	-	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS1_k127_2033326_14	583355.Caka_2448	8.809e-18	83.0	COG0257@1|root,COG0257@2|Bacteria,46TAZ@74201|Verrucomicrobia,3K8GV@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS1_k127_2033326_5	452637.Oter_2545	1.858e-95	321.0	COG0226@1|root,COG0226@2|Bacteria,46SP0@74201|Verrucomicrobia,3K734@414999|Opitutae	414999|Opitutae	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_2033326_1	382464.ABSI01000010_gene3834	1.059e-153	502.0	COG0573@1|root,COG0573@2|Bacteria,46T46@74201|Verrucomicrobia,2ITIR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_2033326_2	452637.Oter_2547	3.516e-132	430.0	COG0581@1|root,COG0581@2|Bacteria,46SBK@74201|Verrucomicrobia,3K77I@414999|Opitutae	414999|Opitutae	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS1_k127_2033326_3	1191523.MROS_2636	7.219e-114	373.0	COG1117@1|root,COG1117@2|Bacteria	2|Bacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS1_k127_2033326_9	278957.ABEA03000195_gene537	3.797e-47	175.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS1_k127_2050042_4	452637.Oter_0484	4.049e-59	212.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,3K7SH@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS1_k127_2050042_5	1177154.Y5S_03314	2.183e-14	82.0	2A9GM@1|root,30YNG@2|Bacteria,1RFB1@1224|Proteobacteria,1SFHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2050042_1	583355.Caka_2570	1.83e-194	615.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K7QV@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS1_k127_2050042_3	335543.Sfum_2320	1.739e-75	258.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,42R0Z@68525|delta/epsilon subdivisions,2WMNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NAD(P)H dehydrogenase (quinone)	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
CMS1_k127_2050042_0	452637.Oter_3486	2.257e-199	642.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia,3K7G8@414999|Opitutae	414999|Opitutae	KL	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
CMS1_k127_2050042_2	794903.OPIT5_30480	6.724e-140	456.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_207766_3	935863.AWZR01000001_gene2032	1.583e-08	59.0	COG1426@1|root,COG1426@2|Bacteria,1QW1U@1224|Proteobacteria,1T5E6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_207766_0	382464.ABSI01000013_gene1916	8.86e-229	744.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	yxiA	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	GH43_C,Glyco_hydro_43,Laminin_G_3
CMS1_k127_207766_1	382464.ABSI01000012_gene2006	5.401e-145	465.0	COG3507@1|root,COG3507@2|Bacteria,46U42@74201|Verrucomicrobia,2IW5D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS1_k127_207766_2	1123236.KB899383_gene2651	2.574e-48	178.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,469AY@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_2083877_1	709991.Odosp_0909	2.727e-13	83.0	COG2319@1|root,COG2319@2|Bacteria,4PNVX@976|Bacteroidetes,2FY8F@200643|Bacteroidia	2|Bacteria	S	PFAM MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,WD40
CMS1_k127_2083877_2	765910.MARPU_08525	3.796e-09	66.0	COG0457@1|root,COG0457@2|Bacteria,1R4NF@1224|Proteobacteria,1S7C1@1236|Gammaproteobacteria,1WZF2@135613|Chromatiales	135613|Chromatiales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10
CMS1_k127_2083877_0	1229780.BN381_210055	1.578e-19	100.0	COG1226@1|root,COG1226@2|Bacteria,2I8YK@201174|Actinobacteria	201174|Actinobacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	-	-	-	-	-	-	-	-	-	RyR,TrkA_N
CMS1_k127_2088028_1	1121920.AUAU01000016_gene1282	1.077e-24	114.0	COG1538@1|root,COG1538@2|Bacteria,3Y4FN@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_2088028_0	452637.Oter_3755	4.064e-54	198.0	COG0424@1|root,COG0424@2|Bacteria,46VD8@74201|Verrucomicrobia,3K804@414999|Opitutae	414999|Opitutae	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_2102633_4	382464.ABSI01000005_gene1151	1.02e-162	522.0	COG0058@1|root,COG0058@2|Bacteria,46S5T@74201|Verrucomicrobia,2IV91@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase
CMS1_k127_2102633_6	794903.OPIT5_01650	2.973e-138	450.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia,3K761@414999|Opitutae	414999|Opitutae	C	AAA domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
CMS1_k127_2102633_8	278957.ABEA03000006_gene4180	1.183e-116	385.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia,3K793@414999|Opitutae	414999|Opitutae	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
CMS1_k127_2102633_5	382464.ABSI01000012_gene2218	1.39e-141	459.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia,2ITIH@203494|Verrucomicrobiae	74201|Verrucomicrobia	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
CMS1_k127_2102633_2	583355.Caka_1340	4.781e-211	679.0	COG0557@1|root,COG0557@2|Bacteria,46U8T@74201|Verrucomicrobia,3K7Q5@414999|Opitutae	414999|Opitutae	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
CMS1_k127_2102633_1	585543.HMPREF0969_02263	3.48e-217	699.0	COG3391@1|root,COG3391@2|Bacteria,4PMVP@976|Bacteroidetes,2G0IC@200643|Bacteroidia,4AR81@815|Bacteroidaceae	976|Bacteroidetes	S	candidate xyloglucanase, glycoside hydrolase family 74 protein K01238	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2102633_7	452637.Oter_1756	1.638e-125	411.0	COG1609@1|root,COG1609@2|Bacteria,46UIZ@74201|Verrucomicrobia,3K8BK@414999|Opitutae	414999|Opitutae	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_2102633_0	1191523.MROS_1644	2.216e-295	934.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	xylS	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14
CMS1_k127_2102633_3	1286632.P278_24260	4.127e-179	589.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,1HXGZ@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS1_k127_2102633_9	452637.Oter_0400	6.567e-67	236.0	COG1360@1|root,COG1360@2|Bacteria,46VC4@74201|Verrucomicrobia,3K7YD@414999|Opitutae	414999|Opitutae	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS1_k127_2119848_1	583355.Caka_1901	2.459e-114	377.0	COG0332@1|root,COG0332@2|Bacteria,46UBS@74201|Verrucomicrobia,3K7QN@414999|Opitutae	414999|Opitutae	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_2119848_3	583355.Caka_1900	1.185e-101	343.0	COG0596@1|root,COG0596@2|Bacteria,46Z8Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha/beta hydrolase fold	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
CMS1_k127_2119848_2	497964.CfE428DRAFT_1577	9.792e-107	359.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
CMS1_k127_2119848_5	298655.KI912267_gene7381	6.362e-12	68.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
CMS1_k127_2119848_0	583355.Caka_2365	5.666e-126	416.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia,3K7S4@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
CMS1_k127_2119848_4	1173026.Glo7428_1003	3.319e-19	89.0	COG1350@1|root,COG1350@2|Bacteria,1G369@1117|Cyanobacteria	1117|Cyanobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS1_k127_2129196_5	1227739.Hsw_2260	8.507e-07	51.0	2DRW6@1|root,33DD7@2|Bacteria,4P53S@976|Bacteroidetes	976|Bacteroidetes	S	NTF2 fold immunity protein	-	-	-	-	-	-	-	-	-	-	-	-	Imm-NTF2-2
CMS1_k127_2129196_1	497964.CfE428DRAFT_3828	3.837e-25	109.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_C39,RHS_repeat
CMS1_k127_2129196_2	1396141.BATP01000056_gene3277	6.13e-18	93.0	COG3209@1|root,COG3209@2|Bacteria,46TP7@74201|Verrucomicrobia,2IVDA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CMS1_k127_2129196_0	1411685.U062_00611	8.623e-70	253.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	AAA_25,DUF3987,DnaB_C,Toprim_2,Toprim_4
CMS1_k127_2129196_4	1121022.ABENE_06880	3.877e-14	74.0	COG1476@1|root,COG1476@2|Bacteria,1QUSF@1224|Proteobacteria,2TZAM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
CMS1_k127_2129196_3	903818.KI912268_gene3246	8.637e-16	82.0	COG3550@1|root,COG3550@2|Bacteria,3Y4V9@57723|Acidobacteria	57723|Acidobacteria	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
CMS1_k127_213432_1	382464.ABSI01000011_gene2993	1.043e-96	322.0	COG1028@1|root,COG1028@2|Bacteria,46X2H@74201|Verrucomicrobia,2IVMC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_213432_5	332101.JIBU02000048_gene3608	8.418e-10	67.0	28P4A@1|root,2ZBZJ@2|Bacteria,1V39Y@1239|Firmicutes,24UPB@186801|Clostridia,36Q0P@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_213432_3	278957.ABEA03000188_gene1492	3.346e-68	243.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,3K7CE@414999|Opitutae	414999|Opitutae	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS1_k127_213432_0	452637.Oter_3749	1.308e-104	346.0	COG3267@1|root,COG3267@2|Bacteria,46SXM@74201|Verrucomicrobia,3K91Q@414999|Opitutae	414999|Opitutae	U	Pfam:Arch_ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
CMS1_k127_213432_4	583355.Caka_1910	2.453e-11	68.0	COG2919@1|root,COG2919@2|Bacteria,46XW4@74201|Verrucomicrobia,3K8FZ@414999|Opitutae	414999|Opitutae	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CMS1_k127_213432_2	443144.GM21_0054	1.075e-72	252.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2140610_3	580332.Slit_1471	0.0009656	49.0	2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,2VT7Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_2140610_1	887062.HGR_09269	1.757e-65	229.0	2BN8J@1|root,32GW0@2|Bacteria,1RH74@1224|Proteobacteria	1224|Proteobacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
CMS1_k127_2140610_0	1304888.ATWF01000001_gene627	2.453e-76	274.0	COG3087@1|root,COG3087@2|Bacteria,2GF99@200930|Deferribacteres	200930|Deferribacteres	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2140610_2	580332.Slit_2104	8.764e-38	145.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,44VWH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS1_k127_2148208_0	1410613.JNKF01000011_gene1141	8.084e-140	456.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,2FQHN@200643|Bacteroidia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	malL	-	3.2.1.1,3.2.1.10,3.2.1.20,5.4.99.16	ko:K01182,ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R01718,R01791,R02108,R02112,R06087,R06088,R06199,R11262	RC00028,RC00049,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
CMS1_k127_2148208_1	583355.Caka_2817	6.314e-52	187.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_2159239_3	1470593.BW43_05542	1.709e-85	290.0	2EJTI@1|root,33DI5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_2159239_2	452637.Oter_2556	1.136e-95	320.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,3K7US@414999|Opitutae	414999|Opitutae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS1_k127_2159239_4	1304885.AUEY01000014_gene3344	4.693e-70	244.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2WNBT@28221|Deltaproteobacteria,2MJ2U@213118|Desulfobacterales	28221|Deltaproteobacteria	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
CMS1_k127_2159239_1	1123288.SOV_5c03000	6.054e-101	337.0	COG0289@1|root,COG0289@2|Bacteria,1UYP1@1239|Firmicutes,4H1V4@909932|Negativicutes	909932|Negativicutes	E	Dihydrodipicolinate reductase, C-terminus	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS1_k127_2159239_6	1397527.Q670_04220	2.539e-33	134.0	2D6VZ@1|root,32TMY@2|Bacteria,1N3V2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2159239_0	583355.Caka_1541	5.699e-148	482.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia,3K7N2@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
CMS1_k127_2159239_5	382464.ABSI01000005_gene1031	1.248e-46	173.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia	74201|Verrucomicrobia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_2168861_4	251221.35212532	1.816e-22	115.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
CMS1_k127_2168861_5	1499967.BAYZ01000054_gene4793	2.608e-18	96.0	2B1Z8@1|root,31UFT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
CMS1_k127_2168861_1	278963.ATWD01000001_gene2042	7.948e-49	190.0	COG1835@1|root,COG1835@2|Bacteria,3Y3FZ@57723|Acidobacteria,2JIU7@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_2168861_6	1122981.AUME01000046_gene1630	5.71e-15	85.0	COG3315@1|root,COG3315@2|Bacteria,4NI9Z@976|Bacteroidetes	976|Bacteroidetes	Q	Psort location Cytoplasmic, score	tcmP	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS1_k127_2168861_0	584708.Apau_1985	1.115e-65	237.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183,ko:K15256	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS1_k127_2173978_2	867845.KI911784_gene3722	1.14e-08	57.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2173978_1	278957.ABEA03000189_gene988	8.292e-12	73.0	COG1317@1|root,COG1317@2|Bacteria,46WNQ@74201|Verrucomicrobia,3K8A1@414999|Opitutae	414999|Opitutae	NU	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
CMS1_k127_2173978_0	794903.OPIT5_24845	1.3e-166	535.0	COG1157@1|root,COG1157@2|Bacteria,46UKN@74201|Verrucomicrobia,3K7FP@414999|Opitutae	414999|Opitutae	N	ATP synthase alpha/beta family, beta-barrel domain	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_2220288_1	452637.Oter_0424	7.259e-126	421.0	COG1766@1|root,COG1766@2|Bacteria,46UUW@74201|Verrucomicrobia,3K76G@414999|Opitutae	414999|Opitutae	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
CMS1_k127_2220288_9	573061.Clocel_1713	3.182e-11	70.0	COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,259BR@186801|Clostridia,36MTT@31979|Clostridiaceae	186801|Clostridia	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
CMS1_k127_2220288_4	278957.ABEA03000189_gene992	4.209e-39	150.0	COG1558@1|root,COG1558@2|Bacteria,46VMA@74201|Verrucomicrobia,3K86M@414999|Opitutae	414999|Opitutae	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS1_k127_2220288_7	794903.OPIT5_24815	9.648e-20	94.0	COG1815@1|root,COG1815@2|Bacteria,46WGM@74201|Verrucomicrobia,3K89P@414999|Opitutae	414999|Opitutae	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
CMS1_k127_2220288_2	382464.ABSI01000023_gene525	2.601e-56	205.0	COG2928@1|root,COG2928@2|Bacteria,46VCC@74201|Verrucomicrobia,2IUXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS1_k127_2220288_6	382464.ABSI01000023_gene524	1.675e-20	99.0	COG1381@1|root,COG1381@2|Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0008150,GO:0009314,GO:0009628,GO:0050896	2.6.99.2	ko:K03474,ko:K03584	ko00750,ko01100,ko03440,map00750,map01100,map03440	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	RecO_C,RecO_N
CMS1_k127_2220288_0	794903.OPIT5_01070	4.425e-148	474.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS1_k127_2220288_8	452637.Oter_2790	7.768e-19	91.0	COG0457@1|root,COG0457@2|Bacteria,46Z69@74201|Verrucomicrobia,3K8AP@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2220288_3	583355.Caka_1272	9.594e-46	171.0	COG0735@1|root,COG0735@2|Bacteria,46V9Y@74201|Verrucomicrobia,3K81W@414999|Opitutae	414999|Opitutae	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_2220288_5	452637.Oter_2792	6.404e-35	139.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia,3K7V0@414999|Opitutae	414999|Opitutae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
CMS1_k127_2226821_2	452637.Oter_0475	1.161e-74	258.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,3K73G@414999|Opitutae	414999|Opitutae	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS1_k127_2226821_4	583355.Caka_2578	3.566e-28	119.0	COG0713@1|root,COG0713@2|Bacteria,46YZN@74201|Verrucomicrobia,3K88N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS1_k127_2226821_3	583355.Caka_2577	7.886e-31	128.0	COG0839@1|root,COG0839@2|Bacteria,46YZM@74201|Verrucomicrobia,3K89U@414999|Opitutae	414999|Opitutae	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS1_k127_2226821_0	794903.OPIT5_14145	3.676e-81	273.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,3K7UR@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS1_k127_2226821_1	583355.Caka_2575	7.239e-75	257.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K7UD@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS1_k127_2228815_2	344747.PM8797T_04660	2.345e-12	70.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2228815_0	583355.Caka_0908	1.078e-204	645.0	COG0696@1|root,COG0696@2|Bacteria,46U4C@74201|Verrucomicrobia,3K7DS@414999|Opitutae	414999|Opitutae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS1_k127_228058_1	314230.DSM3645_10497	4.035e-94	329.0	COG1807@1|root,COG1807@2|Bacteria,2IZVF@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_228058_0	666681.M301_1823	1.799e-118	388.0	COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,2VJTM@28216|Betaproteobacteria,2KNKJ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
CMS1_k127_228058_2	382464.ABSI01000011_gene2915	3.648e-33	130.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia,2ITRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_2307353_7	596151.DesfrDRAFT_2151	5.089e-97	320.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NQ9@68525|delta/epsilon subdivisions,2WM2K@28221|Deltaproteobacteria,2M815@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the group II decarboxylase family	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
CMS1_k127_2307353_9	1123070.KB899265_gene1868	1.128e-51	192.0	2EU5N@1|root,32KSV@2|Bacteria,46X68@74201|Verrucomicrobia,2IUN0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2307353_1	497964.CfE428DRAFT_4635	3.73e-215	674.0	COG0683@1|root,COG0683@2|Bacteria,46TNV@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Periplasmic binding protein	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
CMS1_k127_2307353_4	452637.Oter_4228	3.406e-138	460.0	COG0559@1|root,COG0559@2|Bacteria,46U7D@74201|Verrucomicrobia,3K73C@414999|Opitutae	414999|Opitutae	P	Urea ABC transporter permease	-	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
CMS1_k127_2307353_3	1123070.KB899265_gene1856	3.073e-144	466.0	COG4177@1|root,COG4177@2|Bacteria,46S8E@74201|Verrucomicrobia,2ITTE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_2307353_5	583355.Caka_2152	1.341e-111	366.0	COG4674@1|root,COG4674@2|Bacteria,46SHS@74201|Verrucomicrobia,3K7CS@414999|Opitutae	414999|Opitutae	S	urea ABC transporter, ATP-binding protein	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2307353_8	583355.Caka_2153	1.519e-84	292.0	COG0410@1|root,COG0410@2|Bacteria,46TST@74201|Verrucomicrobia,3K7VH@414999|Opitutae	414999|Opitutae	E	urea ABC transporter, ATP-binding protein	-	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
CMS1_k127_2307353_0	1123393.KB891330_gene884	0.0	1463.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,2WGI2@28216|Betaproteobacteria	28216|Betaproteobacteria	EI	urea carboxylase	uca	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
CMS1_k127_2307353_2	768671.ThimaDRAFT_2230	1.011e-188	606.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1WXE4@135613|Chromatiales	135613|Chromatiales	J	Allophanate hydrolase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS1_k127_2307353_10	158190.SpiGrapes_0206	7.316e-47	177.0	COG1802@1|root,COG1802@2|Bacteria,2JA9X@203691|Spirochaetes	203691|Spirochaetes	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_2307353_6	338963.Pcar_0046	7.401e-101	368.0	COG4625@1|root,COG4870@1|root,COG4625@2|Bacteria,COG4870@2|Bacteria,1MU92@1224|Proteobacteria,42Q0T@68525|delta/epsilon subdivisions,2WM1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
CMS1_k127_2307353_13	1144275.COCOR_07358	0.0008427	51.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
CMS1_k127_2307353_11	497964.CfE428DRAFT_4386	3.592e-15	78.0	COG3039@1|root,COG3039@2|Bacteria,46WXW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS1_k127_2322651_0	583355.Caka_1545	7.882e-209	656.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia,3K7CW@414999|Opitutae	414999|Opitutae	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
CMS1_k127_2322651_6	1499689.CCNN01000009_gene2789	1.849e-78	265.0	COG0454@1|root,COG0456@2|Bacteria,1V2FB@1239|Firmicutes,24CAZ@186801|Clostridia,36GYD@31979|Clostridiaceae	186801|Clostridia	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_2322651_8	382464.ABSI01000011_gene3017	1.201e-61	220.0	COG0363@1|root,COG0363@2|Bacteria,46T8I@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	nagB	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CMS1_k127_2322651_7	404380.Gbem_2786	8.628e-72	247.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,42QR5@68525|delta/epsilon subdivisions,2WMSR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Lipocalin family protein	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
CMS1_k127_2322651_4	886379.AEWI01000001_gene1696	9.545e-106	352.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,2FMG5@200643|Bacteroidia,3XJ04@558415|Marinilabiliaceae	976|Bacteroidetes	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS1_k127_2322651_1	583355.Caka_2691	1.854e-133	434.0	COG1194@1|root,COG1194@2|Bacteria,46SR4@74201|Verrucomicrobia,3K760@414999|Opitutae	414999|Opitutae	L	iron-sulfur cluster	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS1_k127_2322651_5	661478.OP10G_2561	6.718e-80	276.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
CMS1_k127_2322651_2	398767.Glov_0712	1.13e-115	379.0	COG0371@1|root,COG0371@2|Bacteria,1MWAE@1224|Proteobacteria,42PJS@68525|delta/epsilon subdivisions,2WJ69@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS1_k127_2322651_9	313624.NSP_33470	6.898e-12	74.0	COG0371@1|root,COG0371@2|Bacteria,1G19U@1117|Cyanobacteria,1HKCY@1161|Nostocales	1117|Cyanobacteria	C	PFAM Iron-containing alcohol dehydrogenase	gldA	-	1.1.1.1,1.1.1.6	ko:K00001,ko:K00005	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01034,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10715,R10717	RC00029,RC00050,RC00087,RC00088,RC00099,RC00116,RC00117,RC00649,RC00670,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	iJN678.gldA	Fe-ADH
CMS1_k127_2322651_3	794903.OPIT5_27125	3.171e-110	364.0	COG0787@1|root,COG0787@2|Bacteria,46UBN@74201|Verrucomicrobia,3K796@414999|Opitutae	414999|Opitutae	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS1_k127_2386926_2	880072.Desac_0820	7.962e-15	79.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WKM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
CMS1_k127_2386926_1	706587.Desti_5587	7.218e-52	187.0	COG1908@1|root,COG1908@2|Bacteria,1RGF7@1224|Proteobacteria,42S3H@68525|delta/epsilon subdivisions,2WNTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS1_k127_2386926_0	696369.KI912183_gene1133	1.619e-214	685.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,Pyr_redox_2
CMS1_k127_238707_0	1282360.ABAC460_00245	0.0	1281.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31,PA14
CMS1_k127_238707_1	452637.Oter_3214	0.0	1194.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
CMS1_k127_238707_2	661478.OP10G_2650	3.339e-199	642.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
CMS1_k127_2395848_1	596151.DesfrDRAFT_0110	9.513e-26	113.0	2CVVV@1|root,32SYG@2|Bacteria,1N1QK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2395848_0	382464.ABSI01000011_gene2604	1.923e-108	361.0	COG2204@1|root,COG2204@2|Bacteria,46TZX@74201|Verrucomicrobia,2IV20@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_2400834_3	583355.Caka_0238	9.995e-70	250.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,HMA
CMS1_k127_2400834_4	1163408.UU9_05574	6.742e-34	136.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1S8ZG@1236|Gammaproteobacteria,1XBZV@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind
CMS1_k127_2400834_6	1142394.PSMK_22350	0.0005274	50.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_1,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
CMS1_k127_2400834_0	583355.Caka_2234	4.521e-216	685.0	COG0029@1|root,COG0029@2|Bacteria,46SHQ@74201|Verrucomicrobia,3K72T@414999|Opitutae	414999|Opitutae	H	L-aspartate oxidase	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_2400834_2	742726.HMPREF9448_02646	4.48e-71	247.0	COG4912@1|root,COG4912@2|Bacteria,4NKBS@976|Bacteroidetes,2FM3U@200643|Bacteroidia,22XNZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS1_k127_2400834_1	649639.Bcell_0437	1.784e-89	307.0	COG2730@1|root,COG2730@2|Bacteria,1TSJQ@1239|Firmicutes,4HFEH@91061|Bacilli,1ZEYQ@1386|Bacillus	91061|Bacilli	G	PFAM glycoside hydrolase family 5	bglC5	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
CMS1_k127_2400834_5	398512.JQKC01000103_gene2699	2.955e-18	85.0	COG0524@1|root,COG0524@2|Bacteria,1UYHM@1239|Firmicutes,24DYS@186801|Clostridia,3WIP7@541000|Ruminococcaceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_241546_6	1163398.AJJP01000063_gene3132	5.189e-18	87.0	COG1432@1|root,COG1432@2|Bacteria,1MYP8@1224|Proteobacteria	1224|Proteobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_241546_1	177439.DP1580	3.445e-81	297.0	COG4928@1|root,COG4928@2|Bacteria,1MWRP@1224|Proteobacteria,42TK1@68525|delta/epsilon subdivisions,2WT2J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
CMS1_k127_241546_0	596153.Alide_0478	9.956e-94	327.0	COG2131@1|root,COG2131@2|Bacteria,1PNTH@1224|Proteobacteria,2VPVS@28216|Betaproteobacteria	28216|Betaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CMS1_k127_241546_4	497964.CfE428DRAFT_1407	1.084e-28	130.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_241546_7	697281.Mahau_2532	2.455e-07	57.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,42EVU@68295|Thermoanaerobacterales	186801|Clostridia	S	beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
CMS1_k127_241546_3	1121940.AUDZ01000005_gene1912	1.206e-40	154.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1XK2F@135619|Oceanospirillales	135619|Oceanospirillales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS1_k127_241546_5	521674.Plim_0909	4.19e-23	104.0	COG4747@1|root,COG4747@2|Bacteria,2IZK3@203682|Planctomycetes	203682|Planctomycetes	S	COG4747 ACT domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_241546_2	794903.OPIT5_27540	3.082e-62	224.0	COG1354@1|root,COG1354@2|Bacteria,46UZS@74201|Verrucomicrobia,3K76V@414999|Opitutae	414999|Opitutae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS1_k127_2422810_0	1453503.AU05_24275	2.718e-265	835.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1YFKT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS1_k127_2422810_1	86106.I862_02825	4.797e-72	260.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2TSW4@28211|Alphaproteobacteria,47GQP@766|Rickettsiales	766|Rickettsiales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS1_k127_2422810_2	1129374.AJE_11219	1.391e-20	94.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,1RPXN@1236|Gammaproteobacteria,467XW@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Transcriptional regulator	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
CMS1_k127_2434895_1	382464.ABSI01000010_gene3289	5.501e-123	420.0	COG0642@1|root,COG2205@2|Bacteria,46TGZ@74201|Verrucomicrobia,2IV3X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_2434895_3	452637.Oter_1686	1.495e-61	219.0	COG1272@1|root,COG1272@2|Bacteria,46T25@74201|Verrucomicrobia,3K7KU@414999|Opitutae	74201|Verrucomicrobia	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS1_k127_2434895_6	794903.OPIT5_16305	4.273e-06	57.0	295DN@1|root,2ZSRI@2|Bacteria,46WWE@74201|Verrucomicrobia,3K80Z@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2434895_5	382464.ABSI01000012_gene2114	4.033e-27	121.0	COG0726@1|root,COG0726@2|Bacteria,46UKH@74201|Verrucomicrobia,2IU6W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
CMS1_k127_2434895_4	794903.OPIT5_16315	3.197e-48	179.0	COG1327@1|root,COG1327@2|Bacteria,46VCN@74201|Verrucomicrobia,3K7XU@414999|Opitutae	414999|Opitutae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS1_k127_2434895_2	382464.ABSI01000016_gene669	2.172e-90	301.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia,2IU46@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_2434895_0	382464.ABSI01000016_gene670	1.094e-149	483.0	COG0343@1|root,COG0343@2|Bacteria,46TZR@74201|Verrucomicrobia,2ITG4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_2438103_2	452637.Oter_0384	4.771e-07	55.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,46UGA@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
CMS1_k127_2438103_0	452637.Oter_3180	3.066e-133	439.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,3K7R4@414999|Opitutae	414999|Opitutae	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CMS1_k127_2438103_1	926554.KI912633_gene3969	7.63e-130	422.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_248741_5	1296416.JACB01000031_gene2532	3.104e-56	203.0	2CIH2@1|root,2ZBC0@2|Bacteria,4NKD5@976|Bacteroidetes,1HZKH@117743|Flavobacteriia,2YITT@290174|Aquimarina	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
CMS1_k127_248741_0	349741.Amuc_1710	5.105e-207	666.0	COG0514@1|root,COG0514@2|Bacteria,46U82@74201|Verrucomicrobia,2ITT4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS1_k127_248741_3	452637.Oter_0180	2.523e-105	355.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,3K7BD@414999|Opitutae	414999|Opitutae	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_248741_2	452637.Oter_0181	2.71e-111	378.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,46S7Z@74201|Verrucomicrobia,3K7FH@414999|Opitutae	414999|Opitutae	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS1_k127_248741_1	1441930.Z042_25125	2.317e-136	445.0	COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,3ZZYT@613|Serratia	1236|Gammaproteobacteria	I	Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
CMS1_k127_248741_6	1191523.MROS_0616	3.399e-36	147.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K03406,ko:K07216	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Hemerythrin,MCPsignal,PilJ
CMS1_k127_248741_4	720554.Clocl_3836	6.745e-100	335.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24FI8@186801|Clostridia,3WGQ5@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2501287_2	1121918.ARWE01000001_gene1725	1.177e-36	144.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria	1224|Proteobacteria	M	Epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_2501287_0	794903.OPIT5_28445	2.932e-199	627.0	COG0677@1|root,COG0677@2|Bacteria	2|Bacteria	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	wbpA	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_2501287_1	382464.ABSI01000011_gene2729	4.444e-98	326.0	COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia,2ITYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_2541156_7	646529.Desaci_2388	5.811e-10	60.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,260FM@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
CMS1_k127_2541156_3	452637.Oter_4153	7.206e-111	371.0	COG0263@1|root,COG0263@2|Bacteria,46SWM@74201|Verrucomicrobia,3K78E@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS1_k127_2541156_2	452637.Oter_0051	2.992e-116	379.0	COG2877@1|root,COG2877@2|Bacteria,46SMZ@74201|Verrucomicrobia,3K7E4@414999|Opitutae	414999|Opitutae	M	2-dehydro-3-deoxyphosphooctonate aldolase	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS1_k127_2541156_1	349520.PPE_01074	1.694e-124	428.0	COG0671@1|root,COG4625@1|root,COG0671@2|Bacteria,COG4625@2|Bacteria,1UYVP@1239|Firmicutes,4HF6D@91061|Bacilli,26V0P@186822|Paenibacillaceae	91061|Bacilli	I	Membrane-associated phospholipid phosphatase	epsA	-	-	-	-	-	-	-	-	-	-	-	PAP2,PATR,SLH
CMS1_k127_2541156_0	382464.ABSI01000011_gene3052	4.316e-195	629.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,2IU3F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS1_k127_2541156_4	1316936.K678_00505	7.148e-99	340.0	COG0471@1|root,COG0471@2|Bacteria,1N58G@1224|Proteobacteria,2TU92@28211|Alphaproteobacteria,2JR21@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp
CMS1_k127_2541156_6	1300345.LF41_1273	7.837e-62	220.0	COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_2541156_8	349161.Dred_2970	2.684e-07	59.0	COG0642@1|root,COG0642@2|Bacteria,1UZTI@1239|Firmicutes,24FQ6@186801|Clostridia,264AX@186807|Peptococcaceae	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_2541156_5	876269.ARWA01000001_gene430	6.31e-80	271.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,2U2F7@28211|Alphaproteobacteria,3NC95@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_2545660_0	583355.Caka_2069	0.0	1486.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,46U8Z@74201|Verrucomicrobia,3K95E@414999|Opitutae	414999|Opitutae	EI	Pfam:AHS1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
CMS1_k127_2545660_4	583355.Caka_2070	6.731e-97	321.0	COG3665@1|root,COG3665@2|Bacteria,46YTE@74201|Verrucomicrobia,3K9BA@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
CMS1_k127_2545660_3	583355.Caka_2071	1.592e-103	341.0	COG3665@1|root,COG3665@2|Bacteria,46UDI@74201|Verrucomicrobia,3K9G8@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
CMS1_k127_2545660_5	1313301.AUGC01000004_gene2343	9.877e-67	247.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes	976|Bacteroidetes	M	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2545660_2	382464.ABSI01000011_gene2917	1.273e-139	480.0	COG1629@1|root,COG4771@2|Bacteria,46TY6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_2545660_7	1121920.AUAU01000014_gene2821	1.183e-08	61.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_2545660_1	794903.OPIT5_13510	3.558e-177	563.0	COG0208@1|root,COG0208@2|Bacteria,46SMW@74201|Verrucomicrobia,3K7VI@414999|Opitutae	414999|Opitutae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS1_k127_2545660_6	452637.Oter_4599	5.866e-28	119.0	COG1943@1|root,COG1943@2|Bacteria,46XXH@74201|Verrucomicrobia,3K8JN@414999|Opitutae	414999|Opitutae	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS1_k127_2550589_1	583355.Caka_1512	4.737e-142	464.0	COG1624@1|root,COG1762@1|root,COG1624@2|Bacteria,COG1762@2|Bacteria,46TVS@74201|Verrucomicrobia,3K7HC@414999|Opitutae	414999|Opitutae	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N,PTS_EIIA_2
CMS1_k127_2550589_2	794903.OPIT5_18775	2.072e-30	124.0	COG0838@1|root,COG0838@2|Bacteria,46VUH@74201|Verrucomicrobia,3K878@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS1_k127_2550589_0	583355.Caka_0735	1.658e-142	461.0	COG0045@1|root,COG0045@2|Bacteria,46TDG@74201|Verrucomicrobia,3K7AB@414999|Opitutae	414999|Opitutae	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_2552857_1	1122915.AUGY01000028_gene5880	7.111e-16	81.0	COG0464@1|root,COG0464@2|Bacteria,1TSG1@1239|Firmicutes,4IQTF@91061|Bacilli,276IM@186822|Paenibacillaceae	91061|Bacilli	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS1_k127_2552857_0	714943.Mucpa_5696	4.455e-150	504.0	COG0507@1|root,COG0507@2|Bacteria,4NHCF@976|Bacteroidetes,1IQ7G@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC,Viral_helicase1
CMS1_k127_2559935_0	382464.ABSI01000007_gene4188	1.232e-167	569.0	COG0642@1|root,COG2205@2|Bacteria,46TGZ@74201|Verrucomicrobia,2IV71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HATPase_c,HisKA,Response_reg
CMS1_k127_2559935_1	398767.Glov_3370	4.412e-43	171.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
CMS1_k127_2559935_2	452637.Oter_3614	5.258e-28	118.0	COG3250@1|root,COG3250@2|Bacteria,46U2Y@74201|Verrucomicrobia,3K7KS@414999|Opitutae	414999|Opitutae	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_2610934_0	278957.ABEA03000041_gene2092	7.411e-168	547.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,3K747@414999|Opitutae	414999|Opitutae	L	exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_2610934_5	1173264.KI913949_gene2585	7.442e-35	141.0	COG1738@1|root,COG1738@2|Bacteria	2|Bacteria	S	queuosine salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS1_k127_2610934_1	382464.ABSI01000013_gene1505	8.51e-91	305.0	COG0217@1|root,COG0217@2|Bacteria,46SP3@74201|Verrucomicrobia,2IU5Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS1_k127_2610934_2	278957.ABEA03000161_gene60	1.765e-70	243.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia,3K74U@414999|Opitutae	414999|Opitutae	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS1_k127_2610934_3	794903.OPIT5_12165	2.292e-69	245.0	COG2264@1|root,COG2264@2|Bacteria,46SYY@74201|Verrucomicrobia,3K733@414999|Opitutae	414999|Opitutae	J	L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS1_k127_2610934_6	1206744.BAGL01000122_gene3005	0.0001658	50.0	COG5513@1|root,COG5513@2|Bacteria,2GXM1@201174|Actinobacteria,4G4J0@85025|Nocardiaceae	201174|Actinobacteria	S	Chagasin family peptidase inhibitor I42	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Inhibitor_I42
CMS1_k127_2610934_4	382464.ABSI01000021_gene359	2.566e-62	226.0	COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_2648211_3	583355.Caka_2702	1.099e-41	158.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,3K7VV@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_2648211_1	794903.OPIT5_25205	1.407e-94	317.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia,3K74Q@414999|Opitutae	414999|Opitutae	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS1_k127_2648211_0	398767.Glov_3113	2.012e-111	394.0	COG0642@1|root,COG2984@1|root,COG2205@2|Bacteria,COG2984@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HAMP,HATPase_c,HisKA,Pkinase,Response_reg
CMS1_k127_2648211_2	1396418.BATQ01000166_gene1900	3.11e-81	278.0	COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,2ITZR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
CMS1_k127_2661829_1	382464.ABSI01000016_gene666	3.219e-15	75.0	COG0537@1|root,COG0537@2|Bacteria,46SZ4@74201|Verrucomicrobia,2IUKK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FG	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS1_k127_2661829_0	583355.Caka_1790	1.372e-92	317.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia,3K7Y8@414999|Opitutae	414999|Opitutae	G	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS1_k127_2661829_2	1116472.MGMO_141c00110	5.589e-08	60.0	2DRCC@1|root,33B76@2|Bacteria,1NGYQ@1224|Proteobacteria,1SQM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2670217_7	1189612.A33Q_0689	9.605e-06	52.0	COG1396@1|root,COG1396@2|Bacteria,4NPYD@976|Bacteroidetes,47PQQ@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_2670217_6	382464.ABSI01000016_gene709	1.774e-19	90.0	COG1987@1|root,COG1987@2|Bacteria,46WWK@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Bacterial export proteins, family 3	-	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
CMS1_k127_2670217_5	382464.ABSI01000016_gene710	8.466e-33	137.0	COG1684@1|root,COG1684@2|Bacteria,46WEA@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Bacterial export proteins, family 1	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
CMS1_k127_2670217_2	452637.Oter_0406	1.501e-91	313.0	COG1377@1|root,COG1377@2|Bacteria,46U7X@74201|Verrucomicrobia,3K76M@414999|Opitutae	414999|Opitutae	NU	FlhB HrpN YscU SpaS Family	-	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
CMS1_k127_2670217_0	382464.ABSI01000016_gene712	6.78e-249	787.0	COG1298@1|root,COG1298@2|Bacteria,46TTN@74201|Verrucomicrobia	74201|Verrucomicrobia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
CMS1_k127_2670217_4	452637.Oter_0404	2.685e-58	217.0	COG1419@1|root,COG1419@2|Bacteria,46VBY@74201|Verrucomicrobia,3K9JP@414999|Opitutae	414999|Opitutae	N	protein localization to endoplasmic reticulum	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	-
CMS1_k127_2670217_3	452637.Oter_0402	4.568e-73	255.0	COG1191@1|root,COG1191@2|Bacteria,46TPW@74201|Verrucomicrobia,3K7F7@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_2670217_1	452637.Oter_0401	1.312e-97	326.0	COG1291@1|root,COG1291@2|Bacteria,46UCQ@74201|Verrucomicrobia,3K773@414999|Opitutae	414999|Opitutae	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CMS1_k127_2670852_1	1004785.AMBLS11_15145	4.195e-48	183.0	COG1629@1|root,COG4771@2|Bacteria,1MUF1@1224|Proteobacteria,1RQF8@1236|Gammaproteobacteria,469J0@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
CMS1_k127_2670852_0	452637.Oter_1363	1.82e-168	542.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2
CMS1_k127_2685703_0	278957.ABEA03000010_gene3912	8.01e-67	232.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_2685703_3	269798.CHU_0606	1.751e-22	109.0	COG1442@1|root,COG1442@2|Bacteria,4NNA2@976|Bacteroidetes,47R6V@768503|Cytophagia	976|Bacteroidetes	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2685703_2	269798.CHU_0606	1.27e-23	113.0	COG1442@1|root,COG1442@2|Bacteria,4NNA2@976|Bacteroidetes,47R6V@768503|Cytophagia	976|Bacteroidetes	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2685703_1	794903.OPIT5_27990	2.824e-36	140.0	COG0788@1|root,COG0788@2|Bacteria,46SMH@74201|Verrucomicrobia,3K78Z@414999|Opitutae	414999|Opitutae	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
CMS1_k127_2735756_0	583355.Caka_1909	2.765e-230	731.0	COG1109@1|root,COG1109@2|Bacteria,46SB1@74201|Verrucomicrobia,3K7CC@414999|Opitutae	414999|Opitutae	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
CMS1_k127_2735756_2	1410631.JHWZ01000011_gene1973	4.465e-127	417.0	COG3392@1|root,COG3392@2|Bacteria,1TRWE@1239|Firmicutes,248Q7@186801|Clostridia,27Q26@186928|unclassified Lachnospiraceae	186801|Clostridia	L	D12 class N6 adenine-specific DNA methyltransferase	fokIM	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
CMS1_k127_2735756_3	1156937.MFUM_920018	1.109e-93	324.0	COG0260@1|root,COG0260@2|Bacteria,46UWM@74201|Verrucomicrobia,37GDP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepB	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS1_k127_2735756_1	794903.OPIT5_16215	9.558e-160	510.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,3K759@414999|Opitutae	414999|Opitutae	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_2735756_4	589865.DaAHT2_1661	3.653e-79	285.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N0F@68525|delta/epsilon subdivisions,2WJAE@28221|Deltaproteobacteria,2MIUP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal
CMS1_k127_2735756_5	794903.OPIT5_19990	1.367e-23	100.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,3K7JR@414999|Opitutae	414999|Opitutae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_2781212_5	714943.Mucpa_3792	1.394e-09	62.0	COG1493@1|root,COG1493@2|Bacteria,4NSUZ@976|Bacteroidetes,1IVWU@117747|Sphingobacteriia	976|Bacteroidetes	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2781212_2	980584.AFPB01000142_gene1236	6.215e-132	452.0	COG3250@1|root,COG3250@2|Bacteria,4NEDF@976|Bacteroidetes,1IIHI@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Malectin
CMS1_k127_2781212_3	404380.Gbem_0780	9.57e-99	332.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,42PBT@68525|delta/epsilon subdivisions,2WMAY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
CMS1_k127_2781212_1	517418.Ctha_0789	5.521e-184	581.0	COG1979@1|root,COG1979@2|Bacteria,1FFQH@1090|Chlorobi	1090|Chlorobi	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K08325	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R02528,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC00739,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS1_k127_2781212_0	1235835.C814_02784	3.801e-228	710.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
CMS1_k127_2781212_4	1232443.BAIA02000075_gene461	8.145e-30	118.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,26A0Y@186813|unclassified Clostridiales	186801|Clostridia	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
CMS1_k127_2785932_5	382464.ABSI01000010_gene3353	1.078e-49	180.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000010_gene3353|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2785932_1	1227739.Hsw_3933	1.708e-232	739.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47TCZ@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_2785932_3	446471.Xcel_2665	1.354e-172	557.0	COG1874@1|root,COG1874@2|Bacteria,2IE1F@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4978,Glyco_hydro_35,Glyco_hydro_42,RicinB_lectin_2
CMS1_k127_2785932_2	452637.Oter_3209	3.395e-198	634.0	COG3693@1|root,COG3693@2|Bacteria,46UVW@74201|Verrucomicrobia,3K7XQ@414999|Opitutae	414999|Opitutae	G	Beta-xylanase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
CMS1_k127_2785932_0	452637.Oter_4344	0.0	1024.0	2DB7A@1|root,2Z7KK@2|Bacteria,46UIN@74201|Verrucomicrobia,3KA3H@414999|Opitutae	2|Bacteria	S	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115,Glyco_hydro_67N
CMS1_k127_2785932_4	1004149.AFOE01000043_gene1698	8.49e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,1HX7K@117743|Flavobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2785932_6	583355.Caka_0457	1.7e-37	145.0	COG1312@1|root,COG1312@2|Bacteria,46UDP@74201|Verrucomicrobia,3K8B6@414999|Opitutae	414999|Opitutae	G	Catalyzes the dehydration of D-mannonate	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_2807034_2	203122.Sde_2868	2.504e-39	153.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria,1SAFU@1236|Gammaproteobacteria,46DJS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
CMS1_k127_2807034_1	344747.PM8797T_24041	6.984e-70	243.0	COG0500@1|root,COG2226@2|Bacteria,2IZHY@203682|Planctomycetes	203682|Planctomycetes	H	ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2807034_0	1304872.JAGC01000003_gene2874	4.079e-127	415.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42ZMZ@68525|delta/epsilon subdivisions,2X27A@28221|Deltaproteobacteria,2M8TC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2811202_0	1120985.AUMI01000005_gene2471	4.683e-76	269.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,4H2VG@909932|Negativicutes	909932|Negativicutes	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
CMS1_k127_2811202_1	1328313.DS2_05455	8.347e-13	74.0	2ARR8@1|root,31H2B@2|Bacteria,1RJXW@1224|Proteobacteria,1S8JP@1236|Gammaproteobacteria,46790@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2811480_2	926564.KI911619_gene4007	1.739e-05	51.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_2811480_1	1415780.JPOG01000001_gene3057	7.058e-79	282.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1XCNQ@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_2811480_0	1297863.APJF01000025_gene2983	5.457e-127	413.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3JV04@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS1_k127_2813429_1	583355.Caka_2996	1.628e-86	297.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia,3K7P8@414999|Opitutae	414999|Opitutae	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS1_k127_2813429_0	240016.ABIZ01000001_gene4206	2.449e-242	781.0	COG0612@1|root,COG0612@2|Bacteria,46UTT@74201|Verrucomicrobia,2ITM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_2813429_3	1122963.AUHB01000005_gene2668	8.352e-38	145.0	COG4319@1|root,COG4319@2|Bacteria,1N8K3@1224|Proteobacteria,2UXUT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS1_k127_2813429_2	382464.ABSI01000010_gene3578	1.192e-55	199.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia,2ITIW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_2826200_1	382464.ABSI01000010_gene3635	1.292e-22	98.0	2E99J@1|root,329Q3@2|Bacteria,46Z0T@74201|Verrucomicrobia,2IWAH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2826200_2	67352.JODS01000028_gene2372	4.364e-14	83.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_2826200_0	1283284.AZUK01000001_gene1521	2.589e-150	482.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1Y4Z7@135624|Aeromonadales	135624|Aeromonadales	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS1_k127_2859164_1	583355.Caka_2992	5.408e-148	476.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,3K76C@414999|Opitutae	414999|Opitutae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS1_k127_2859164_4	1366050.N234_05440	9.78e-57	206.0	COG0500@1|root,COG0500@2|Bacteria,1NJRR@1224|Proteobacteria,2VZI1@28216|Betaproteobacteria,1KBKA@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2859164_0	583355.Caka_2991	1.736e-170	540.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_2859164_3	382464.ABSI01000013_gene1732	2.14e-64	240.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_2859164_6	1121403.AUCV01000033_gene3672	6.322e-27	113.0	COG3952@1|root,COG3952@2|Bacteria,1NFUX@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
CMS1_k127_2859164_2	583355.Caka_1724	5.799e-74	255.0	COG0463@1|root,COG0463@2|Bacteria,46VFD@74201|Verrucomicrobia,3K9NN@414999|Opitutae	414999|Opitutae	M	PFAM glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS1_k127_2859164_5	398767.Glov_0769	2.788e-43	164.0	COG3907@1|root,COG3907@2|Bacteria,1QV68@1224|Proteobacteria,42V5Q@68525|delta/epsilon subdivisions,2WRMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS1_k127_2882124_14	583355.Caka_1734	3.24e-39	155.0	COG3216@1|root,COG3216@2|Bacteria,46WES@74201|Verrucomicrobia,3K9VH@414999|Opitutae	414999|Opitutae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
CMS1_k127_2882124_12	583355.Caka_2213	2.074e-46	173.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_2882124_11	794903.OPIT5_17170	5.131e-47	176.0	COG0817@1|root,COG0817@2|Bacteria,46VH2@74201|Verrucomicrobia,3K7RW@414999|Opitutae	414999|Opitutae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS1_k127_2882124_9	278957.ABEA03000060_gene3152	1.926e-77	273.0	COG1195@1|root,COG1195@2|Bacteria,46UKV@74201|Verrucomicrobia,3K7K7@414999|Opitutae	414999|Opitutae	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CMS1_k127_2882124_2	382464.ABSI01000014_gene1435	6.382e-180	576.0	COG1282@1|root,COG1282@2|Bacteria,46SBC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_2882124_15	382464.ABSI01000014_gene1434	3.079e-30	122.0	COG3288@1|root,COG3288@2|Bacteria,46T7S@74201|Verrucomicrobia	74201|Verrucomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
CMS1_k127_2882124_5	382464.ABSI01000014_gene1433	2.019e-141	458.0	COG3288@1|root,COG3288@2|Bacteria,46SFW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_2882124_13	1304885.AUEY01000005_gene864	8.028e-40	168.0	COG3527@1|root,COG3527@2|Bacteria,1MWDZ@1224|Proteobacteria,42R9C@68525|delta/epsilon subdivisions,2WN1P@28221|Deltaproteobacteria,2MJJP@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM alpha-acetolactate decarboxylase	-	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
CMS1_k127_2882124_1	794903.OPIT5_20520	4.714e-191	608.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_2882124_4	1123070.KB899252_gene821	2.987e-151	491.0	COG0738@1|root,COG0738@2|Bacteria,46VVQ@74201|Verrucomicrobia,2IU7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2882124_10	591023.AM202_0372	7.101e-63	218.0	COG4154@1|root,COG4154@2|Bacteria,1RJ03@1224|Proteobacteria,1S27Q@1236|Gammaproteobacteria,1Y8P4@135625|Pasteurellales	135625|Pasteurellales	G	Involved in the anomeric conversion of L-fucose	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
CMS1_k127_2882124_0	794903.OPIT5_17310	1.832e-192	604.0	COG1063@1|root,COG1063@2|Bacteria,46Z6B@74201|Verrucomicrobia,3K9BT@414999|Opitutae	414999|Opitutae	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2882124_3	382464.ABSI01000017_gene57	7.979e-175	552.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	-	-	1.1.1.2,1.1.1.307	ko:K00002,ko:K17743	ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220	M00014	R00746,R01041,R01431,R01481,R05231,R09477	RC00087,RC00088,RC00099,RC00108,RC00133	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Aldo_ket_red
CMS1_k127_2882124_7	382464.ABSI01000017_gene58	7.556e-111	365.0	COG2207@1|root,COG2207@2|Bacteria,46VFS@74201|Verrucomicrobia,2IVVR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS1_k127_2882124_8	583355.Caka_2309	4.583e-95	325.0	COG1466@1|root,COG1466@2|Bacteria,46U09@74201|Verrucomicrobia,3K7M7@414999|Opitutae	414999|Opitutae	L	DNA polymerase III	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS1_k127_2882124_6	382464.ABSI01000011_gene2906	2.641e-111	369.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_2883788_5	1198232.CYCME_2374	1.198e-30	127.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,461AT@72273|Thiotrichales	72273|Thiotrichales	NU	Belongs to the N-Me-Phe pilin family	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CMS1_k127_2883788_1	1198232.CYCME_2375	1.89e-114	394.0	COG0457@1|root,COG0457@2|Bacteria,1R50I@1224|Proteobacteria,1RSP6@1236|Gammaproteobacteria,462D9@72273|Thiotrichales	72273|Thiotrichales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2883788_2	105559.Nwat_2538	7.511e-89	318.0	COG0457@1|root,COG0457@2|Bacteria,1R50I@1224|Proteobacteria,1RSP6@1236|Gammaproteobacteria,1WY6N@135613|Chromatiales	135613|Chromatiales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2883788_0	768671.ThimaDRAFT_3471	2.451e-120	392.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1WXRS@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2883788_3	1005048.CFU_0822	1.308e-77	269.0	COG2227@1|root,COG2227@2|Bacteria,1R0XD@1224|Proteobacteria,2WHXW@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2883788_6	1342301.JASD01000008_gene679	2.235e-24	113.0	COG2227@1|root,COG2227@2|Bacteria,1NB77@1224|Proteobacteria,2UARG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_2883788_4	1342301.JASD01000008_gene678	1.052e-34	148.0	COG0438@1|root,COG0438@2|Bacteria,1RCNE@1224|Proteobacteria,2U7UM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS1_k127_290118_1	278957.ABEA03000201_gene4322	4.101e-57	203.0	COG4174@1|root,COG4174@2|Bacteria	2|Bacteria	P	ABC transporter (Permease)	oppB_2	-	-	ko:K02033,ko:K13894	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
CMS1_k127_290118_0	945550.VISI1226_11077	2.191e-124	407.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1XT25@135623|Vibrionales	135623|Vibrionales	P	transport system permease component	yejE	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
CMS1_k127_290118_2	583355.Caka_2145	1.395e-51	192.0	COG0357@1|root,COG0357@2|Bacteria,46VAP@74201|Verrucomicrobia,3K82P@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS1_k127_290118_3	583355.Caka_2534	3.64e-44	173.0	COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,3K7CG@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS1_k127_2919912_2	1328313.DS2_14714	7.814e-05	47.0	COG3311@1|root,COG3311@2|Bacteria,1N779@1224|Proteobacteria,1SCHD@1236|Gammaproteobacteria,468MR@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS1_k127_2919912_0	714943.Mucpa_5696	3.168e-184	610.0	COG0507@1|root,COG0507@2|Bacteria,4NHCF@976|Bacteroidetes,1IQ7G@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC,Viral_helicase1
CMS1_k127_2919912_1	762903.Pedsa_1276	3.558e-68	237.0	COG1196@1|root,COG1196@2|Bacteria,4NQFT@976|Bacteroidetes	976|Bacteroidetes	D	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
CMS1_k127_2920756_0	1232410.KI421425_gene1521	9.628e-246	767.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,43SDT@69541|Desulfuromonadales	28221|Deltaproteobacteria	A	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS1_k127_2920756_1	1232410.KI421425_gene1520	3.206e-46	168.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
CMS1_k127_293525_6	880072.Desac_1783	1.359e-22	98.0	COG0154@1|root,COG0154@2|Bacteria,1MZSF@1224|Proteobacteria,4305X@68525|delta/epsilon subdivisions,2WV81@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	protein, GvpL GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
CMS1_k127_293525_9	880072.Desac_1782	7.432e-15	77.0	2EJC3@1|root,33D37@2|Bacteria,1N89T@1224|Proteobacteria,433DP@68525|delta/epsilon subdivisions,2WXH8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	GvpG
CMS1_k127_293525_2	880072.Desac_1781	1.658e-191	618.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42MT4@68525|delta/epsilon subdivisions,2WKZD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CMS1_k127_293525_11	706587.Desti_4951	3.321e-08	63.0	2AJE0@1|root,319ZR@2|Bacteria,1NM76@1224|Proteobacteria,4337X@68525|delta/epsilon subdivisions,2WX8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
CMS1_k127_293525_8	706587.Desti_4952	8.739e-22	104.0	arCOG06390@1|root,330IR@2|Bacteria,1N8XJ@1224|Proteobacteria,432R5@68525|delta/epsilon subdivisions,2WYHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	GvpK
CMS1_k127_293525_5	880072.Desac_1778	1.331e-30	125.0	2E5BC@1|root,3303G@2|Bacteria,1N7VI@1224|Proteobacteria,431DG@68525|delta/epsilon subdivisions,2WWV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
CMS1_k127_293525_7	794903.OPIT5_04235	2.164e-22	97.0	COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,3K7W3@414999|Opitutae	414999|Opitutae	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS1_k127_293525_1	1408473.JHXO01000012_gene388	3.263e-256	810.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,2FPXV@200643|Bacteroidia	976|Bacteroidetes	S	Fusaric acid resistance protein-like	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
CMS1_k127_293525_0	452662.SJA_C2-02340	4.717e-276	871.0	COG0657@1|root,COG0657@2|Bacteria,1QDQP@1224|Proteobacteria,2U41U@28211|Alphaproteobacteria,2K2PZ@204457|Sphingomonadales	204457|Sphingomonadales	I	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS1_k127_293525_4	504487.JCM19302_993	3.457e-67	239.0	COG1216@1|root,COG1216@2|Bacteria,4NP1S@976|Bacteroidetes,1I3I3@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_293525_10	1392498.JQLH01000001_gene571	2.293e-11	71.0	COG1216@1|root,COG1216@2|Bacteria,4NK0K@976|Bacteroidetes,1I0UB@117743|Flavobacteriia,2PHZ2@252356|Maribacter	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_293525_3	582402.Hbal_1785	1.36e-119	392.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_2938491_2	1500259.JQLD01000010_gene4824	3.997e-08	59.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_2938491_1	1173027.Mic7113_2967	4.886e-52	200.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	2|Bacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_2938491_3	388399.SSE37_02345	5.348e-08	64.0	COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,2TXW7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_2939154_2	926569.ANT_12840	1.424e-34	146.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_2939154_0	926569.ANT_05010	2.261e-134	437.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS1_k127_2939154_1	204669.Acid345_1623	4.345e-119	385.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria,2JKQ8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_294028_1	382464.ABSI01000008_gene4028	4.914e-82	286.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
CMS1_k127_294028_0	1415780.JPOG01000001_gene1965	1.904e-87	302.0	COG4247@1|root,COG4247@2|Bacteria,1NQYG@1224|Proteobacteria,1RS19@1236|Gammaproteobacteria,1X4FY@135614|Xanthomonadales	135614|Xanthomonadales	I	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
CMS1_k127_294028_2	278963.ATWD01000001_gene4496	2.296e-09	62.0	COG0577@1|root,COG0577@2|Bacteria,3Y6C8@57723|Acidobacteria,2JMHC@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_2952506_0	583355.Caka_1517	6.079e-142	452.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,3K740@414999|Opitutae	414999|Opitutae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_2952506_1	278957.ABEA03000044_gene4152	4.261e-87	300.0	COG4974@1|root,COG4974@2|Bacteria,46SSD@74201|Verrucomicrobia,3K7RA@414999|Opitutae	414999|Opitutae	D	tyrosine recombinase	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_2952506_2	671143.DAMO_1776	0.0001089	49.0	COG1516@1|root,COG1516@2|Bacteria,2NS2S@2323|unclassified Bacteria	2|Bacteria	N	flagellar protein fliS	fliS	GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
CMS1_k127_296077_0	1479235.KK366039_gene658	2.228e-164	531.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XHB4@135619|Oceanospirillales	135619|Oceanospirillales	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS1_k127_296077_2	452637.Oter_3002	1.629e-155	501.0	COG2309@1|root,COG2309@2|Bacteria,46SAI@74201|Verrucomicrobia,3K7FF@414999|Opitutae	414999|Opitutae	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS1_k127_296077_4	583355.Caka_0212	3.233e-94	319.0	COG1816@1|root,COG1816@2|Bacteria,46TKQ@74201|Verrucomicrobia,3K75M@414999|Opitutae	414999|Opitutae	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
CMS1_k127_296077_3	382464.ABSI01000005_gene1197	2.016e-114	380.0	COG0476@1|root,COG0476@2|Bacteria,46SGF@74201|Verrucomicrobia,2IU1E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
CMS1_k127_296077_1	452637.Oter_0433	3.498e-159	516.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,46TXM@74201|Verrucomicrobia,3K83U@414999|Opitutae	414999|Opitutae	NT	ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS1_k127_2965411_0	694427.Palpr_0902	4.502e-118	386.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,2FQ6R@200643|Bacteroidia,2304Q@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS1_k127_2965411_1	794903.OPIT5_17265	1.159e-110	371.0	COG1039@1|root,COG1039@2|Bacteria,46UEQ@74201|Verrucomicrobia,3K72V@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_2965411_3	452637.Oter_2098	2.892e-14	75.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,3K7VV@414999|Opitutae	414999|Opitutae	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_2971492_2	583355.Caka_2318	3.131e-90	323.0	2DN50@1|root,32VJ4@2|Bacteria,46TKZ@74201|Verrucomicrobia,3K748@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS1_k127_2971492_0	583355.Caka_2319	4.008e-100	344.0	COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,3K735@414999|Opitutae	414999|Opitutae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS1_k127_2971492_3	794903.OPIT5_12800	5.951e-54	199.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,3K7JF@414999|Opitutae	414999|Opitutae	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS1_k127_2971492_1	452637.Oter_0087	6.515e-93	314.0	COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,3K7S3@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2988103_7	278957.ABEA03000095_gene4601	3.342e-15	76.0	2AX8K@1|root,31P7E@2|Bacteria,46XUD@74201|Verrucomicrobia,3K874@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2988103_2	1232437.KL662061_gene4223	1.303e-74	274.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria,2MINP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
CMS1_k127_2988103_5	382464.ABSI01000013_gene1697	2.033e-39	157.0	COG1639@1|root,COG1639@2|Bacteria,46VUE@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_2988103_6	575540.Isop_2604	1.561e-21	99.0	COG0735@1|root,COG0735@2|Bacteria,2J4JK@203682|Planctomycetes	203682|Planctomycetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_2988103_3	452637.Oter_4099	1.85e-73	267.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia,3K9B6@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
CMS1_k127_2988103_1	880073.Calab_3717	9.146e-86	301.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
CMS1_k127_2988103_0	583355.Caka_2417	2.483e-110	366.0	COG0276@1|root,COG0276@2|Bacteria,46V02@74201|Verrucomicrobia,3K7E1@414999|Opitutae	414999|Opitutae	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS1_k127_2988103_4	324057.Pjdr2_6007	1.101e-46	194.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	3.2.1.8	ko:K01181,ko:K06889	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS1_k127_2992684_3	794903.OPIT5_14940	3.358e-29	117.0	COG4175@1|root,COG4175@2|Bacteria	2|Bacteria	E	quaternary-ammonium-compound-transporting ATPase activity	proV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
CMS1_k127_2992684_2	765912.Thimo_3664	6.145e-123	408.0	COG3746@1|root,COG3746@2|Bacteria,1Q3GY@1224|Proteobacteria,1RNGT@1236|Gammaproteobacteria,1WWCU@135613|Chromatiales	135613|Chromatiales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2992684_0	452637.Oter_2929	0.0	1058.0	COG3250@1|root,COG3250@2|Bacteria,46UWF@74201|Verrucomicrobia,3K7BB@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_2992684_1	382464.ABSI01000017_gene67	4.94e-272	849.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CMS1_k127_300759_0	452637.Oter_2541	7.332e-181	582.0	COG0553@1|root,COG0553@2|Bacteria,46UW7@74201|Verrucomicrobia,3K7NY@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
CMS1_k127_300759_2	583355.Caka_1515	3.685e-26	124.0	COG0457@1|root,COG3107@1|root,COG0457@2|Bacteria,COG3107@2|Bacteria,46WDB@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
CMS1_k127_300759_1	452637.Oter_4593	2.087e-74	268.0	COG2006@1|root,COG2006@2|Bacteria,46T4A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS1_k127_302572_1	29581.BW37_01773	4.537e-14	72.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,473PQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldo/keto reductase family	yakC	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_302572_0	1307761.L21SP2_2727	5.807e-196	638.0	COG1501@1|root,COG1501@2|Bacteria,2J73G@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
CMS1_k127_3032113_10	452637.Oter_3389	0.0001216	51.0	COG4396@1|root,COG4396@2|Bacteria	2|Bacteria	S	Bacteriophage Mu Gam like protein	gam	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_Gam
CMS1_k127_3032113_1	583355.Caka_2957	6.099e-65	226.0	COG0295@1|root,COG0295@2|Bacteria	2|Bacteria	F	cytidine deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP2
CMS1_k127_3032113_6	278957.ABEA03000094_gene4701	8.873e-25	118.0	COG2842@1|root,COG2842@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,Guanylate_cyc,NB-ARC,TIR_2,TPR_10,TPR_12
CMS1_k127_3032113_4	794903.OPIT5_08240	4.468e-37	162.0	2EK76@1|root,30NMS@2|Bacteria,46XQY@74201|Verrucomicrobia,3K9Y8@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3032113_7	583355.Caka_2962	3.849e-23	111.0	COG1475@1|root,COG1475@2|Bacteria,46UYR@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
CMS1_k127_3032113_5	452637.Oter_3395	1.761e-35	151.0	2EK76@1|root,30NMS@2|Bacteria,46XQY@74201|Verrucomicrobia,3K9Y8@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3032113_8	278957.ABEA03000110_gene1335	3.737e-22	109.0	2DY86@1|root,348KN@2|Bacteria,46W4J@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3032113_9	221988.MS0122	8.192e-06	54.0	COG4396@1|root,COG4396@2|Bacteria,1REDK@1224|Proteobacteria,1S3XY@1236|Gammaproteobacteria,1Y8IV@135625|Pasteurellales	135625|Pasteurellales	S	Mu-like prophage host-nuclease inhibitor protein Gam	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_Gam
CMS1_k127_3032113_0	1403819.BATR01000077_gene2240	1.133e-89	321.0	COG0457@1|root,COG0846@1|root,COG0457@2|Bacteria,COG0846@2|Bacteria	2|Bacteria	K	NAD+ binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3032113_3	240016.ABIZ01000001_gene3798	7.763e-44	175.0	COG0582@1|root,COG0582@2|Bacteria,46T2Q@74201|Verrucomicrobia,2IV0J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_3032113_2	983548.Krodi_0094	1.643e-63	243.0	COG5635@1|root,COG5635@2|Bacteria,4NIRY@976|Bacteroidetes,1HZWA@117743|Flavobacteriia	976|Bacteroidetes	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
CMS1_k127_3054865_4	696369.KI912183_gene798	2.544e-18	92.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3054865_2	402881.Plav_2624	3.394e-88	299.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,1JN9C@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Serine acetyltransferase, N-terminal	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS1_k127_3054865_3	1382359.JIAL01000001_gene2836	1.322e-49	184.0	COG1225@1|root,COG1225@2|Bacteria,3Y61N@57723|Acidobacteria,2JMBJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_3054865_6	289376.THEYE_A1814	6.132e-11	72.0	COG0671@1|root,COG0671@2|Bacteria,3J1CX@40117|Nitrospirae	40117|Nitrospirae	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS1_k127_3054865_1	240016.ABIZ01000001_gene1467	1.892e-114	389.0	COG1807@1|root,COG1807@2|Bacteria,46SJQ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3054865_5	314345.SPV1_04978	1.577e-15	90.0	COG3409@1|root,COG3409@2|Bacteria,1NA0X@1224|Proteobacteria	1224|Proteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
CMS1_k127_3054865_0	278957.ABEA03000060_gene3150	1.543e-199	629.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,3K78I@414999|Opitutae	414999|Opitutae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_3055789_5	1200557.JHWV01000019_gene1213	1.395e-39	158.0	COG0845@1|root,COG0845@2|Bacteria,1U1UF@1239|Firmicutes,4H27Y@909932|Negativicutes	909932|Negativicutes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18302	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_3055789_6	1122603.ATVI01000005_gene3153	5.646e-29	126.0	COG1309@1|root,COG1309@2|Bacteria,1PZUN@1224|Proteobacteria,1RY6D@1236|Gammaproteobacteria,1X6AD@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_3055789_7	652103.Rpdx1_4632	5.965e-24	110.0	COG1309@1|root,COG1309@2|Bacteria,1PZUN@1224|Proteobacteria,2TQY3@28211|Alphaproteobacteria,3JRG4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	MA20_44865	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_3055789_8	339670.Bamb_1976	1.833e-13	76.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_3055789_1	1278073.MYSTI_07045	2.95e-152	497.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria	1224|Proteobacteria	KT	Transcriptional regulator	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K12146,ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
CMS1_k127_3055789_2	1144672.F966_03301	1.768e-85	293.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,1T0VK@1236|Gammaproteobacteria,3NPWN@468|Moraxellaceae	1236|Gammaproteobacteria	S	Amidohydrolase	-	-	4.1.1.46,4.1.1.52	ko:K07045,ko:K14333,ko:K22213	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821	RC00390	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS1_k127_3055789_0	86416.Clopa_1376	1.311e-153	490.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,36IF3@31979|Clostridiaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
CMS1_k127_3055789_4	1230476.C207_03938	3.363e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,1N4HB@1224|Proteobacteria,2U1IP@28211|Alphaproteobacteria,3JXG6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_3055789_3	596151.DesfrDRAFT_1013	1.687e-49	200.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MH92@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS1_k127_3056613_0	167539.Pro_1283	1.29e-09	70.0	COG5285@1|root,COG5285@2|Bacteria,1G9QQ@1117|Cyanobacteria	1117|Cyanobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3068953_1	794903.OPIT5_06520	1.201e-135	444.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,3K7HI@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_3068953_6	583355.Caka_2760	2.029e-73	260.0	COG0470@1|root,COG0470@2|Bacteria,46T6T@74201|Verrucomicrobia,3K7VJ@414999|Opitutae	414999|Opitutae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
CMS1_k127_3068953_5	794903.OPIT5_02260	1.638e-76	262.0	COG0125@1|root,COG0125@2|Bacteria,46ST1@74201|Verrucomicrobia,3K7VY@414999|Opitutae	414999|Opitutae	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS1_k127_3068953_2	382464.ABSI01000005_gene1253	9.3e-131	432.0	COG0524@1|root,COG0524@2|Bacteria,46TT7@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_3068953_10	452637.Oter_1666	9.984e-29	126.0	COG1426@1|root,COG1426@2|Bacteria,46VXH@74201|Verrucomicrobia,3K84R@414999|Opitutae	414999|Opitutae	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
CMS1_k127_3068953_8	1121918.ARWE01000001_gene1698	2.426e-45	170.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,43UMR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_3068953_3	933262.AXAM01000014_gene258	7.521e-83	289.0	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,42Q98@68525|delta/epsilon subdivisions,2WM5S@28221|Deltaproteobacteria,2MNQ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
CMS1_k127_3068953_7	452637.Oter_0952	8.632e-62	224.0	2EXV9@1|root,33R4E@2|Bacteria,46UMS@74201|Verrucomicrobia,3K7QR@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3068953_0	583355.Caka_2082	2.045e-147	476.0	COG0592@1|root,COG0592@2|Bacteria,46UBP@74201|Verrucomicrobia,3K7UX@414999|Opitutae	414999|Opitutae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
CMS1_k127_3068953_4	452637.Oter_0954	2.673e-78	272.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,3K7J5@414999|Opitutae	414999|Opitutae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_3068953_9	583355.Caka_2084	1.187e-37	145.0	COG2026@1|root,COG2026@2|Bacteria,46VPJ@74201|Verrucomicrobia,3K85V@414999|Opitutae	414999|Opitutae	DJ	Addiction module toxin, RelE StbE family	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	-
CMS1_k127_3068953_11	330214.NIDE4328	1.396e-21	102.0	COG0350@1|root,COG0350@2|Bacteria,3J1A8@40117|Nitrospirae	40117|Nitrospirae	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CMS1_k127_3068953_13	857087.Metme_2785	9.493e-14	80.0	2C60Y@1|root,32YTG@2|Bacteria,1NCUM@1224|Proteobacteria,1SDA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3070669_0	583355.Caka_1934	5.458e-154	503.0	COG0661@1|root,COG0661@2|Bacteria,46UJV@74201|Verrucomicrobia,3K7NS@414999|Opitutae	414999|Opitutae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_3070669_1	382464.ABSI01000011_gene2987	1.028e-13	74.0	COG3937@1|root,COG3937@2|Bacteria,46WXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3101789_8	760011.Spico_1852	3.61e-12	76.0	COG5184@1|root,COG5184@2|Bacteria,2J8DW@203691|Spirochaetes	203691|Spirochaetes	DZ	COGs COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Mfa_like_1,RCC1,RCC1_2
CMS1_k127_3101789_9	796606.BMMGA3_09390	0.0004386	50.0	COG0491@1|root,COG0491@2|Bacteria,1V2VR@1239|Firmicutes,4IQB8@91061|Bacilli,1ZRIK@1386|Bacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_3101789_3	382464.ABSI01000010_gene3412	4.508e-125	413.0	COG2262@1|root,COG2262@2|Bacteria,46SP4@74201|Verrucomicrobia,2IU26@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_3101789_5	382245.ASA_2404	1.567e-27	127.0	2BH5I@1|root,32B6M@2|Bacteria,1RKHK@1224|Proteobacteria,1S7RV@1236|Gammaproteobacteria,1Y58G@135624|Aeromonadales	135624|Aeromonadales	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
CMS1_k127_3101789_2	547045.NEISICOT_01684	9.535e-126	407.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,2KPIK@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS1_k127_3101789_0	1346330.M472_08175	1.812e-210	673.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
CMS1_k127_3101789_7	278957.ABEA03000150_gene4017	9.752e-14	75.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,46T7C@74201|Verrucomicrobia,3K8J0@414999|Opitutae	414999|Opitutae	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_3101789_6	331678.Cphamn1_1444	2.379e-16	84.0	COG1950@1|root,COG1950@2|Bacteria,1FE4Y@1090|Chlorobi	1090|Chlorobi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CMS1_k127_3101789_4	452637.Oter_3786	3.48e-85	305.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_3101789_1	583355.Caka_3035	2.197e-176	566.0	COG0165@1|root,COG0165@2|Bacteria,46SCX@74201|Verrucomicrobia,3KA2P@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_3110192_2	1304872.JAGC01000003_gene3856	2.88e-66	233.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MATW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
CMS1_k127_3110192_3	583355.Caka_1751	5.047e-59	224.0	COG0037@1|root,COG0037@2|Bacteria,46YXN@74201|Verrucomicrobia,3K8AF@414999|Opitutae	414999|Opitutae	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
CMS1_k127_3110192_0	452637.Oter_2733	5.583e-268	840.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,3K7DV@414999|Opitutae	414999|Opitutae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
CMS1_k127_3110192_1	234267.Acid_3381	1.975e-252	793.0	COG3533@1|root,COG3533@2|Bacteria,3Y7GP@57723|Acidobacteria	57723|Acidobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS1_k127_3156660_6	107636.JQNK01000009_gene2747	1.044e-14	83.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016,ko:K21701	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_3156660_1	582744.Msip34_0415	2.067e-161	535.0	COG4774@1|root,COG4774@2|Bacteria,1MVZD@1224|Proteobacteria,2WHKZ@28216|Betaproteobacteria,2KNQI@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Secretin and TonB N terminus short domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN,TonB_dep_Rec
CMS1_k127_3156660_4	697282.Mettu_1770	1.042e-68	246.0	COG0438@1|root,COG0438@2|Bacteria,1Q04U@1224|Proteobacteria,1TGVU@1236|Gammaproteobacteria,1XGTP@135618|Methylococcales	135618|Methylococcales	H	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_3156660_2	497964.CfE428DRAFT_3007	1.984e-140	456.0	COG1088@1|root,COG1088@2|Bacteria,46S98@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_3156660_3	1267535.KB906767_gene632	1.236e-93	312.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3156660_5	278963.ATWD01000001_gene3285	1.24e-37	145.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_3156660_0	452637.Oter_1897	2.061e-195	636.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_3162350_11	1121413.JMKT01000009_gene1947	6.77e-33	129.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2M8EP@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3162350_6	583355.Caka_2037	2.283e-95	323.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia,3K74B@414999|Opitutae	414999|Opitutae	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_3162350_12	452637.Oter_2374	8.812e-28	119.0	COG1430@1|root,COG1430@2|Bacteria,46WD4@74201|Verrucomicrobia,3K83W@414999|Opitutae	414999|Opitutae	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS1_k127_3162350_16	215803.DB30_0282	8.934e-14	78.0	COG1765@1|root,COG1765@2|Bacteria,1N9KI@1224|Proteobacteria,43BEN@68525|delta/epsilon subdivisions,2X6T6@28221|Deltaproteobacteria,2Z07I@29|Myxococcales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_3162350_7	316067.Geob_2091	1.423e-69	243.0	COG2320@1|root,COG2320@2|Bacteria,1RH46@1224|Proteobacteria,42TFI@68525|delta/epsilon subdivisions,2WP4H@28221|Deltaproteobacteria,43VWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
CMS1_k127_3162350_0	762982.HMPREF9442_01302	0.0	1092.0	2DB7A@1|root,2Z7KK@2|Bacteria,4NGC2@976|Bacteroidetes,2FMN6@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG06097 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115,Glyco_hydro_67N,S_layer_C
CMS1_k127_3162350_4	715226.ABI_10510	1.414e-185	590.0	COG3507@1|root,COG3507@2|Bacteria,1QBSN@1224|Proteobacteria,2U0XU@28211|Alphaproteobacteria,2KHRR@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_43
CMS1_k127_3162350_1	583355.Caka_2558	2.207e-226	711.0	COG0442@1|root,COG0442@2|Bacteria,46SE3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
CMS1_k127_3162350_15	1268237.G114_04133	3.75e-14	79.0	2EB53@1|root,3355S@2|Bacteria,1N5I5@1224|Proteobacteria,1SDYU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1842
CMS1_k127_3162350_10	382464.ABSI01000002_gene4348	2.029e-37	149.0	COG1011@1|root,COG1011@2|Bacteria,46T57@74201|Verrucomicrobia,2IUUA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_3162350_13	382464.ABSI01000011_gene3063	1.963e-21	98.0	COG5512@1|root,COG5512@2|Bacteria,46WT9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS1_k127_3162350_9	1242864.D187_004214	5.531e-39	166.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RF9@68525|delta/epsilon subdivisions,2WNQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_3162350_8	111781.Lepto7376_3027	7.148e-41	172.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H9P9@1150|Oscillatoriales	1117|Cyanobacteria	M	Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
CMS1_k127_3162350_3	1116472.MGMO_53c00510	1.358e-199	629.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1SX3B@1236|Gammaproteobacteria,1XDZ9@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_3162350_2	478741.JAFS01000001_gene1775	8.491e-214	672.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,37FVD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS1_k127_3162350_14	794903.OPIT5_21165	6.134e-21	104.0	COG2197@1|root,COG2197@2|Bacteria,46XU7@74201|Verrucomicrobia,3K85E@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3162350_5	583355.Caka_0006	1.637e-184	589.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,3K7VN@414999|Opitutae	414999|Opitutae	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
CMS1_k127_3163248_1	234267.Acid_6269	3.524e-24	113.0	COG0577@1|root,COG0577@2|Bacteria,3Y6MX@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_3163248_0	452637.Oter_1890	1.086e-68	260.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_3174404_7	304371.MCP_0961	5.083e-33	132.0	COG1322@1|root,arCOG01425@2157|Archaea,2Y1A0@28890|Euryarchaeota	28890|Euryarchaeota	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS1_k127_3174404_1	411468.CLOSCI_01291	1.598e-109	364.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,21YUW@1506553|Lachnoclostridium	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS1_k127_3174404_6	278957.ABEA03000106_gene1846	3.239e-54	199.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia,3K7K4@414999|Opitutae	414999|Opitutae	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_3174404_0	452637.Oter_2312	0.0	1045.0	COG3459@1|root,COG3459@2|Bacteria	2|Bacteria	G	carbohydrate binding	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
CMS1_k127_3174404_3	290317.Cpha266_1072	2.036e-65	233.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_3174404_4	794903.OPIT5_27960	3.335e-63	229.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,3K7YX@414999|Opitutae	414999|Opitutae	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CMS1_k127_3174404_5	583355.Caka_0843	5.877e-56	202.0	COG0290@1|root,COG0290@2|Bacteria,46V47@74201|Verrucomicrobia,3K841@414999|Opitutae	414999|Opitutae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS1_k127_3174404_2	382464.ABSI01000012_gene2189	1.28e-79	294.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_3192937_0	1380355.JNIJ01000067_gene1404	5.854e-129	430.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_8
CMS1_k127_3192937_1	1041146.ATZB01000058_gene4176	1.683e-107	372.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_3192937_2	414684.RC1_3162	1.339e-58	213.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,2JPX3@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS1_k127_3244001_8	468059.AUHA01000002_gene348	9.562e-30	121.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1IQNE@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_3244001_2	406817.XNC1_1003	5.387e-63	231.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
CMS1_k127_3244001_7	329726.AM1_2597	3.413e-38	153.0	COG2720@1|root,COG2720@2|Bacteria,1G62H@1117|Cyanobacteria	1117|Cyanobacteria	V	vancomycin resistance protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	VanW
CMS1_k127_3244001_0	509191.AEDB02000065_gene617	1.587e-89	306.0	COG1181@1|root,COG1181@2|Bacteria,1VEZR@1239|Firmicutes,24ITG@186801|Clostridia,3WKVS@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS1_k127_3244001_3	404380.Gbem_1696	5.69e-63	222.0	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3244001_5	316067.Geob_1842	2.894e-53	198.0	COG3920@1|root,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_3244001_9	1121918.ARWE01000001_gene1751	1.979e-06	49.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_3244001_6	269799.Gmet_2534	1.628e-50	180.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,42STB@68525|delta/epsilon subdivisions,2WP7C@28221|Deltaproteobacteria,43VS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_3244001_4	269799.Gmet_2533	2.115e-53	190.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,42V2I@68525|delta/epsilon subdivisions,2WRI9@28221|Deltaproteobacteria,43VGH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM Addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
CMS1_k127_325858_0	452637.Oter_1754	6.016e-192	636.0	COG1629@1|root,COG1629@2|Bacteria	452637.Oter_1754|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_325858_2	452637.Oter_2993	4.156e-160	519.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2,MFS_3
CMS1_k127_325858_3	452637.Oter_4545	3.471e-78	266.0	COG0740@1|root,COG0740@2|Bacteria,46TSB@74201|Verrucomicrobia,3K79J@414999|Opitutae	414999|Opitutae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_325858_4	452637.Oter_2774	1.994e-50	185.0	COG0693@1|root,COG0693@2|Bacteria,46SYG@74201|Verrucomicrobia,3K830@414999|Opitutae	414999|Opitutae	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS1_k127_325858_1	583355.Caka_1954	6.616e-175	557.0	COG0766@1|root,COG0766@2|Bacteria,46U7P@74201|Verrucomicrobia,3K78X@414999|Opitutae	414999|Opitutae	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_325858_5	177439.DP0247	1.214e-40	170.0	COG4625@1|root,COG4625@2|Bacteria,1N1XG@1224|Proteobacteria,43AFU@68525|delta/epsilon subdivisions,2X5VQ@28221|Deltaproteobacteria,2MNVA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS1_k127_3262448_4	1120983.KB894570_gene1822	2.547e-06	58.0	2C1AI@1|root,346MG@2|Bacteria,1MXI4@1224|Proteobacteria,2U06V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3262448_2	278957.ABEA03000019_gene1894	4.563e-18	88.0	2BFH8@1|root,329AZ@2|Bacteria,46YH7@74201|Verrucomicrobia,3K9K9@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3262448_3	794903.OPIT5_29355	2.52e-09	61.0	2BNS2@1|root,32HFI@2|Bacteria,46YR0@74201|Verrucomicrobia,3KA11@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3262448_1	278957.ABEA03000019_gene1892	4.677e-22	104.0	2A32P@1|root,30RHK@2|Bacteria,46Y90@74201|Verrucomicrobia,3K953@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3262448_0	760011.Spico_1770	2.936e-24	108.0	COG5184@1|root,COG5492@1|root,COG5184@2|Bacteria,COG5492@2|Bacteria,2J8DW@203691|Spirochaetes	203691|Spirochaetes	DZ	COGs COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Mfa_like_1,RCC1,RCC1_2
CMS1_k127_3269011_1	583355.Caka_3136	4.268e-114	379.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia,3K7RB@414999|Opitutae	414999|Opitutae	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CMS1_k127_3269011_2	382464.ABSI01000006_gene905	3.321e-67	261.0	COG1305@1|root,COG1305@2|Bacteria,46WM8@74201|Verrucomicrobia,2IV4E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,TPR_16,Transglut_core
CMS1_k127_3269011_0	452637.Oter_1950	0.0	1233.0	COG0542@1|root,COG0542@2|Bacteria,46S4S@74201|Verrucomicrobia,3K798@414999|Opitutae	414999|Opitutae	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_3273188_0	583355.Caka_2407	2.083e-190	603.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,3K79I@414999|Opitutae	414999|Opitutae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS1_k127_3273188_3	452637.Oter_4026	2.929e-44	167.0	COG0394@1|root,COG0394@2|Bacteria,46W2V@74201|Verrucomicrobia,3K7ZS@414999|Opitutae	414999|Opitutae	T	low molecular weight	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_3273188_5	240016.ABIZ01000001_gene2350	2.218e-25	110.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS1_k127_3273188_1	382464.ABSI01000010_gene3428	1.597e-122	400.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia,2ITSD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS1_k127_3273188_4	452637.Oter_3834	9.083e-33	132.0	2F7QK@1|root,3404U@2|Bacteria,46VV1@74201|Verrucomicrobia,3K9T0@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3273188_2	583355.Caka_1314	7.129e-57	214.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3295464_1	1105031.HMPREF1141_2407	3.761e-83	286.0	COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,24C2M@186801|Clostridia,36FTX@31979|Clostridiaceae	186801|Clostridia	E	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02002,ko:K03406	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00208	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.12	-	-	MCPsignal,OpuAC
CMS1_k127_3295464_0	1358423.N180_00410	1.193e-87	297.0	COG4176@1|root,COG4176@2|Bacteria,4NH0P@976|Bacteroidetes,1IVJG@117747|Sphingobacteriia	976|Bacteroidetes	E	Binding-protein-dependent transport system inner membrane component	opuAB	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
CMS1_k127_3295464_2	1121289.JHVL01000035_gene2622	2.101e-48	179.0	COG4175@1|root,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,25EJ1@186801|Clostridia,36UUX@31979|Clostridiaceae	186801|Clostridia	E	Domain in cystathionine beta-synthase and other proteins.	opuAA	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
CMS1_k127_3308480_2	452637.Oter_2512	4.511e-63	229.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia,3K7IH@414999|Opitutae	414999|Opitutae	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_3308480_1	583355.Caka_1745	8.43e-127	419.0	COG1301@1|root,COG1301@2|Bacteria,46U9C@74201|Verrucomicrobia,3K7YK@414999|Opitutae	414999|Opitutae	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS1_k127_3308480_0	448385.sce7663	8.414e-154	497.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS1_k127_3311406_0	794903.OPIT5_03090	2.19e-123	404.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,3K73J@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
CMS1_k127_3311406_5	1122970.AUHC01000002_gene1402	3.421e-51	205.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWBJ@28211|Alphaproteobacteria,2KEEC@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,MASE1,PAS_3,PAS_4,Response_reg
CMS1_k127_3311406_1	1353537.TP2_08630	8.148e-111	362.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria,2XN2B@285107|Thioclava	28211|Alphaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_3311406_3	794903.OPIT5_16150	3.713e-71	247.0	COG0639@1|root,COG0639@2|Bacteria,46VJ1@74201|Verrucomicrobia,3K7WT@414999|Opitutae	414999|Opitutae	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_3311406_6	941824.TCEL_02357	7.548e-45	170.0	COG1280@1|root,COG1280@2|Bacteria,1V4SU@1239|Firmicutes,24KYP@186801|Clostridia	186801|Clostridia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_3311406_7	497964.CfE428DRAFT_2873	5.267e-32	137.0	2FED1@1|root,346CU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3311406_2	497964.CfE428DRAFT_2871	9.36e-83	294.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	astD	GO:0003674,GO:0003824,GO:0004029,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c20030,iEcHS_1320.EcHS_A1829,ic_1306.c2146	Aldedh
CMS1_k127_3311406_4	1123487.KB892837_gene4087	2.434e-66	237.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,2KUT4@206389|Rhodocyclales	206389|Rhodocyclales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CMS1_k127_3313418_9	1123070.KB899249_gene381	1.493e-22	107.0	COG0389@1|root,COG0389@2|Bacteria,46TUE@74201|Verrucomicrobia,2IVFZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	impB/mucB/samB family	-	-	-	-	-	-	-	-	-	-	-	-	IMS,IMS_C,IMS_HHH
CMS1_k127_3313418_7	583355.Caka_1208	6.119e-51	187.0	COG2094@1|root,COG2094@2|Bacteria,46T70@74201|Verrucomicrobia,3K84U@414999|Opitutae	414999|Opitutae	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
CMS1_k127_3313418_8	1150600.ADIARSV_1791	3.957e-47	173.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS1_k127_3313418_2	452637.Oter_4007	3.968e-86	299.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_24
CMS1_k127_3313418_3	240016.ABIZ01000001_gene558	3.931e-71	258.0	COG0438@1|root,COG0438@2|Bacteria,46VSM@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_3313418_0	373994.Riv7116_5911	4.003e-124	406.0	COG0438@1|root,COG0438@2|Bacteria,1GI78@1117|Cyanobacteria,1HRRB@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_3313418_6	1121438.JNJA01000033_gene1928	1.058e-52	201.0	COG1216@1|root,COG1216@2|Bacteria,1R60D@1224|Proteobacteria,42UZ2@68525|delta/epsilon subdivisions,2WR0Z@28221|Deltaproteobacteria,2MF7I@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1,Glycos_transf_2
CMS1_k127_3313418_4	383372.Rcas_3648	3.217e-65	249.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,2G9DX@200795|Chloroflexi,377P0@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_3313418_5	65393.PCC7424_4246	6.108e-63	240.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1GITX@1117|Cyanobacteria,3KJBU@43988|Cyanothece	1117|Cyanobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
CMS1_k127_3313418_1	292563.Cyast_1449	3.012e-105	359.0	COG0517@1|root,COG0642@1|root,COG2203@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_9,Response_reg
CMS1_k127_3324378_5	1027371.GOALK_116_00190	6.374e-11	66.0	COG0614@1|root,COG0614@2|Bacteria,2HUKC@201174|Actinobacteria,4GFIH@85026|Gordoniaceae	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
CMS1_k127_3324378_3	595536.ADVE02000003_gene4084	4.633e-53	202.0	COG0535@1|root,COG0535@2|Bacteria,1R9RB@1224|Proteobacteria,2U1ZU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3324378_1	1134912.AJTV01000011_gene2482	8.6e-83	281.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,36Z7I@31993|Methylocystaceae	28211|Alphaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_3324378_4	1131814.JAFO01000001_gene3771	1.236e-47	172.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,3EYHM@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_3324378_0	876269.ARWA01000001_gene2796	7.609e-100	332.0	COG1120@1|root,COG1120@2|Bacteria,1R98F@1224|Proteobacteria,2VF14@28211|Alphaproteobacteria,3ND0K@45404|Beijerinckiaceae	28211|Alphaproteobacteria	HP	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS1_k127_3324378_2	382464.ABSI01000013_gene1860	4.992e-78	265.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia,2IWNG@203494|Verrucomicrobiae	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3325155_7	452637.Oter_2844	1.971e-16	82.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,3K7TQ@414999|Opitutae	414999|Opitutae	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_3325155_5	583355.Caka_2466	2.811e-31	130.0	COG1388@1|root,COG1388@2|Bacteria,46WB7@74201|Verrucomicrobia,3K845@414999|Opitutae	414999|Opitutae	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_3325155_6	278957.ABEA03000060_gene3088	3.696e-19	92.0	COG5074@1|root,COG5074@2|Bacteria,46W5A@74201|Verrucomicrobia,3K8CX@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3325155_0	716541.ECL_02274	1.67e-282	876.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,3X1P6@547|Enterobacter	1236|Gammaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_1778	Fumerase,Fumerase_C
CMS1_k127_3325155_1	583355.Caka_1577	3.151e-130	422.0	COG0552@1|root,COG0552@2|Bacteria,46SKC@74201|Verrucomicrobia,3K7EX@414999|Opitutae	414999|Opitutae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS1_k127_3325155_2	485915.Dret_1009	1.37e-114	387.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M96Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_2,sCache_2
CMS1_k127_3325155_3	583355.Caka_2233	3.625e-99	331.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,3K7TI@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_3325155_4	1121405.dsmv_2066	1.104e-70	244.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2MHTU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_3337609_3	748449.Halha_0250	1.504e-34	135.0	COG0119@1|root,COG0119@2|Bacteria,1TRIK@1239|Firmicutes,249Q4@186801|Clostridia,3WACK@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_3337609_2	1123256.KB907938_gene570	1.594e-49	179.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1X7B3@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative member of DMT superfamily (DUF486)	-	-	-	-	-	-	-	-	-	-	-	-	DMT_6
CMS1_k127_3337609_1	382464.ABSI01000021_gene421	1.963e-53	189.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia,2IUGB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Nitrogen regulatory protein P-II	-	-	-	-	-	-	-	-	-	-	-	-	P-II
CMS1_k127_3337609_0	382464.ABSI01000021_gene420	4.331e-152	496.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,2ITWC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
CMS1_k127_3351642_1	1158165.KB898880_gene1537	5.384e-30	120.0	COG2026@1|root,COG2026@2|Bacteria,1N80B@1224|Proteobacteria,1SDK6@1236|Gammaproteobacteria,1WZ7U@135613|Chromatiales	135613|Chromatiales	DJ	PFAM plasmid	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CMS1_k127_3351642_3	1517416.IDAT_10430	3.958e-21	95.0	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria,1SCC9@1236|Gammaproteobacteria,2QH16@267893|Idiomarinaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
CMS1_k127_3351642_0	1415779.JOMH01000001_gene55	6.531e-69	240.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X3FD@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CMS1_k127_3358934_1	243090.RB5195	1.209e-44	169.0	COG3119@1|root,COG3119@2|Bacteria,2J1QG@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_3358934_2	1123242.JH636434_gene3841	3.327e-37	142.0	COG1484@1|root,COG1484@2|Bacteria,2J3U3@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
CMS1_k127_3358934_3	338966.Ppro_1017	3.779e-14	76.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
CMS1_k127_3358934_0	1122919.KB905607_gene4632	8.908e-79	293.0	COG3525@1|root,COG3525@2|Bacteria,1U0Q5@1239|Firmicutes,4IA5E@91061|Bacilli,272DT@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3369499_3	869213.JCM21142_93544	6.179e-05	45.0	COG3411@1|root,COG3411@2|Bacteria,4NT9G@976|Bacteroidetes	976|Bacteroidetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
CMS1_k127_3369499_2	443143.GM18_1504	3.311e-17	83.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,42RG9@68525|delta/epsilon subdivisions,2WP09@28221|Deltaproteobacteria,43TWE@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulatory protein LysR	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
CMS1_k127_3369499_0	583355.Caka_2831	1.217e-98	334.0	COG0119@1|root,COG0119@2|Bacteria,46TSC@74201|Verrucomicrobia,3K7VG@414999|Opitutae	414999|Opitutae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
CMS1_k127_3369499_4	382464.ABSI01000021_gene399	0.0002231	46.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
CMS1_k127_3371000_0	497964.CfE428DRAFT_3828	4.161e-306	1001.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_C39,RHS_repeat
CMS1_k127_3371000_1	452637.Oter_3065	4.083e-51	194.0	COG0823@1|root,COG3210@1|root,COG5276@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3739,Germane,Gmad1,Haemagg_act,LVIVD
CMS1_k127_3374138_3	1177179.A11A3_04555	4.55e-67	235.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XII4@135619|Oceanospirillales	135619|Oceanospirillales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS1_k127_3374138_2	589865.DaAHT2_0683	1.702e-82	283.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MIQY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS1_k127_3374138_5	644282.Deba_0603	2.218e-63	226.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
CMS1_k127_3374138_6	1121403.AUCV01000040_gene4299	3.229e-28	125.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WJYG@28221|Deltaproteobacteria,2MJBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS1_k127_3374138_0	1121459.AQXE01000005_gene1544	5.588e-92	331.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,2MHHP@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
CMS1_k127_3374138_1	596152.DesU5LDRAFT_0991	5.42e-83	289.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1R6YN@1224|Proteobacteria,42Q4G@68525|delta/epsilon subdivisions,2WJM9@28221|Deltaproteobacteria,2M947@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS1_k127_3374138_4	1167006.UWK_01301	2.306e-65	229.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R6F@68525|delta/epsilon subdivisions,2WN2B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
CMS1_k127_3380545_0	583355.Caka_2075	9.588e-179	568.0	COG0600@1|root,COG0600@2|Bacteria,46UMU@74201|Verrucomicrobia,3K937@414999|Opitutae	414999|Opitutae	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_3380545_1	583355.Caka_2077	2.614e-146	470.0	COG0715@1|root,COG0715@2|Bacteria,46U9E@74201|Verrucomicrobia,3K8I0@414999|Opitutae	414999|Opitutae	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_3380545_3	583355.Caka_2078	4.757e-49	179.0	COG0864@1|root,COG0864@2|Bacteria,46VKS@74201|Verrucomicrobia,3K9VQ@414999|Opitutae	414999|Opitutae	K	NikR C terminal nickel binding domain	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
CMS1_k127_3380545_2	1121033.AUCF01000004_gene4823	1.318e-49	183.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TR00@28211|Alphaproteobacteria,2JQVT@204441|Rhodospirillales	204441|Rhodospirillales	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS1_k127_338835_0	382464.ABSI01000013_gene1701	4.686e-08	63.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,DUF3365,GGDEF,HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1
CMS1_k127_3408252_1	452637.Oter_1890	5.863e-51	200.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_3408252_0	1396141.BATP01000022_gene403	6.085e-163	524.0	COG1219@1|root,COG1219@2|Bacteria,46SIK@74201|Verrucomicrobia,2ITIB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS1_k127_3408252_2	515635.Dtur_1088	5.419e-09	57.0	COG0740@1|root,COG0740@2|Bacteria	2|Bacteria	OU	serine-type endopeptidase activity	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_3410673_0	452637.Oter_2438	5.358e-140	464.0	COG4166@1|root,COG4166@2|Bacteria,46ZJQ@74201|Verrucomicrobia,3K79R@414999|Opitutae	414999|Opitutae	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS1_k127_3410673_2	583355.Caka_1576	1.028e-48	179.0	COG0781@1|root,COG0781@2|Bacteria,46VCF@74201|Verrucomicrobia,3K81J@414999|Opitutae	414999|Opitutae	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS1_k127_3410673_1	583355.Caka_0248	9.072e-61	221.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_3410699_6	330214.NIDE0804	1.623e-09	70.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K03407,ko:K07678,ko:K14978	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506,M00663	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
CMS1_k127_3410699_5	1121918.ARWE01000001_gene2874	5.735e-15	87.0	COG0784@1|root,COG3275@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_3410699_4	583355.Caka_1800	5.881e-34	137.0	COG2042@1|root,COG2042@2|Bacteria	2|Bacteria	S	rRNA processing	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	DTW,Ribo_biogen_C
CMS1_k127_3410699_0	382464.ABSI01000005_gene1366	4.684e-119	389.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3410699_7	373903.Hore_11320	8.902e-06	55.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,25PSP@186801|Clostridia,3WBN8@53433|Halanaerobiales	186801|Clostridia	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_3410699_1	765952.PUV_07580	4.088e-98	332.0	COG0687@1|root,COG0687@2|Bacteria,2JGD6@204428|Chlamydiae	204428|Chlamydiae	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CMS1_k127_3410699_2	1444711.CCJF01000005_gene1485	5.171e-78	269.0	COG1177@1|root,COG1177@2|Bacteria,2JFN9@204428|Chlamydiae	204428|Chlamydiae	P	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_3410699_3	765952.PUV_07600	1.017e-44	166.0	COG1176@1|root,COG1176@2|Bacteria,2JG99@204428|Chlamydiae	204428|Chlamydiae	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_3413774_17	583355.Caka_0242	3.169e-11	69.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07676,ko:K07687,ko:K10715,ko:K20976	ko02020,ko02024,ko02025,ko02026,map02020,map02024,map02025,map02026	M00474,M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg
CMS1_k127_3413774_8	1122214.AQWH01000052_gene425	3.487e-59	212.0	COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,2U84N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	pecS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_3413774_3	1177928.TH2_01005	4.421e-129	419.0	COG0697@1|root,COG0697@2|Bacteria,1MY0D@1224|Proteobacteria,2TRTK@28211|Alphaproteobacteria,2JPGG@204441|Rhodospirillales	204441|Rhodospirillales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15269	-	-	-	-	ko00000,ko02000	2.A.7.3.3	-	-	EamA
CMS1_k127_3413774_10	572480.Arnit_1592	1.624e-49	183.0	COG3545@1|root,COG3545@2|Bacteria,1RKTI@1224|Proteobacteria,42TNI@68525|delta/epsilon subdivisions,2YQ2R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
CMS1_k127_3413774_7	1121440.AUMA01000005_gene2633	2.407e-67	240.0	COG1148@1|root,COG1578@1|root,COG1148@2|Bacteria,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2WMCD@28221|Deltaproteobacteria,2MBST@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
CMS1_k127_3413774_12	469381.Dpep_1714	2.164e-43	162.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_3413774_4	370438.PTH_0585	1.176e-94	320.0	COG1149@1|root,COG1149@2|Bacteria,1TQI9@1239|Firmicutes,2484J@186801|Clostridia,261J0@186807|Peptococcaceae	186801|Clostridia	C	Cobyrinic acid ac-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
CMS1_k127_3413774_6	338963.Pcar_0748	6.901e-86	295.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
CMS1_k127_3413774_16	1121459.AQXE01000008_gene804	6.397e-21	98.0	COG1433@1|root,COG1433@2|Bacteria,1MZ77@1224|Proteobacteria,42U3G@68525|delta/epsilon subdivisions,2WQ5N@28221|Deltaproteobacteria,2MB0I@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
CMS1_k127_3413774_13	690850.Desaf_1822	3.174e-31	126.0	COG1433@1|root,COG1433@2|Bacteria,1QI4Y@1224|Proteobacteria,437CM@68525|delta/epsilon subdivisions,2X2I7@28221|Deltaproteobacteria,2MD04@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
CMS1_k127_3413774_11	404380.Gbem_3661	1.659e-46	183.0	COG3659@1|root,COG3659@2|Bacteria,1Q0I4@1224|Proteobacteria,42WBJ@68525|delta/epsilon subdivisions,2WS5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	-	-	-	-	-	-	-	-	-	OprB
CMS1_k127_3413774_0	909663.KI867150_gene300	0.0	1029.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MR4V@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_3413774_19	1123274.KB899407_gene334	6.051e-09	59.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03711,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	-	-	-	FUR,FeoA
CMS1_k127_3413774_5	909663.KI867150_gene298	8.151e-91	305.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2WPIC@28221|Deltaproteobacteria,2MQGE@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Iron (Metal) dependent repressor, DtxR family	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_3413774_18	292459.STH410	5.318e-10	65.0	COG0640@1|root,COG0640@2|Bacteria,1VPBF@1239|Firmicutes,24VJN@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_3413774_1	1150626.PHAMO_270247	3.947e-201	639.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,2JUG5@204441|Rhodospirillales	204441|Rhodospirillales	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_3413774_15	583355.Caka_2863	5.509e-23	100.0	2C06Z@1|root,3335S@2|Bacteria	2|Bacteria	S	PFAM Nitrogen fixation protein of	-	-	-	-	-	-	-	-	-	-	-	-	Nif11
CMS1_k127_3413774_14	760192.Halhy_4000	6.094e-24	110.0	COG4929@1|root,COG4929@2|Bacteria,4NQB4@976|Bacteroidetes	976|Bacteroidetes	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
CMS1_k127_3413774_9	1134912.AJTV01000061_gene3984	1.06e-51	200.0	COG4872@1|root,COG4872@2|Bacteria,1N3FM@1224|Proteobacteria	1224|Proteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS1_k127_3413774_2	583355.Caka_0008	2.48e-142	467.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,3K76H@414999|Opitutae	414999|Opitutae	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_3431570_2	1485544.JQKP01000002_gene1366	7.75e-14	76.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,44W1W@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF493)	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
CMS1_k127_3431570_0	562970.Btus_1291	1.395e-83	285.0	COG1028@1|root,COG1028@2|Bacteria,1UVX7@1239|Firmicutes,4I3D9@91061|Bacilli,279U1@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3431570_1	3075.A0A087SPC4	2.96e-34	134.0	KOG2532@1|root,KOG2532@2759|Eukaryota,37K63@33090|Viridiplantae,34GX8@3041|Chlorophyta	3041|Chlorophyta	G	Major Facilitator Superfamily	-	-	-	ko:K08193	-	-	-	-	ko00000,ko02000	2.A.1.14	-	-	MFS_1
CMS1_k127_3432825_3	342113.DM82_3970	7.326e-13	72.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,1K198@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3432825_0	861299.J421_1872	2.913e-171	548.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
CMS1_k127_3432825_2	861299.J421_1872	4.352e-36	138.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
CMS1_k127_3432825_1	211165.AJLN01000061_gene3947	3.458e-121	397.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1JK2A@1189|Stigonemataceae	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_3466006_1	452637.Oter_0866	4.528e-250	800.0	COG1629@1|root,COG1629@2|Bacteria,46UE0@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
CMS1_k127_3466006_0	1237149.C900_03894	1.183e-271	853.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,47JIF@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase 97	-	-	3.2.1.20,3.2.1.3	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01790,R01791,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31,GH97	-	GH97_C,GH97_N,Glyco_hydro_97
CMS1_k127_3466006_2	1168034.FH5T_08540	2.495e-140	455.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,2FMHS@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	amyA2	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
CMS1_k127_3479320_3	1453501.JELR01000001_gene2852	7.631e-36	139.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465WB@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Fibronectin type III-like domain	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_3479320_0	278957.ABEA03000073_gene2997	7.138e-147	483.0	COG2985@1|root,COG2985@2|Bacteria,46UXA@74201|Verrucomicrobia,3K80M@414999|Opitutae	414999|Opitutae	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
CMS1_k127_3479320_1	1392540.P256_01689	4.81e-139	449.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,3NR12@468|Moraxellaceae	1236|Gammaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapC	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iJR904.b1416,iJR904.b1417	Gp_dh_C,Gp_dh_N
CMS1_k127_3479320_2	1196095.GAPWK_1223	2.892e-51	187.0	COG1309@1|root,COG1309@2|Bacteria,1PE6A@1224|Proteobacteria,1SF8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
CMS1_k127_3479320_4	877455.Metbo_1039	8.517e-17	87.0	COG3920@1|root,arCOG05183@1|root,arCOG02335@2157|Archaea,arCOG05183@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,HisKA_7TM,PAS,PAS_9,PocR
CMS1_k127_3499990_15	452637.Oter_0009	3.07e-14	76.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,3K75C@414999|Opitutae	414999|Opitutae	L	Helicase associated domain (HA2)  Add an annotation	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
CMS1_k127_3499990_8	240016.ABIZ01000001_gene3270	1.067e-48	182.0	COG1878@1|root,COG1878@2|Bacteria,46TBA@74201|Verrucomicrobia,2IWAE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS1_k127_3499990_1	583355.Caka_0932	1.907e-320	995.0	COG0296@1|root,COG0296@2|Bacteria,46SH5@74201|Verrucomicrobia,3K74A@414999|Opitutae	414999|Opitutae	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS1_k127_3499990_5	583355.Caka_0933	5.172e-89	319.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,3K7FX@414999|Opitutae	414999|Opitutae	M	Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
CMS1_k127_3499990_9	382464.ABSI01000011_gene3010	1.08e-48	195.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS1_k127_3499990_14	583355.Caka_2951	1.34e-17	84.0	COG0333@1|root,COG0333@2|Bacteria,46WWH@74201|Verrucomicrobia,3K8FQ@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS1_k127_3499990_4	452637.Oter_3600	7.329e-114	377.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,3K797@414999|Opitutae	414999|Opitutae	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS1_k127_3499990_0	382464.ABSI01000011_gene2518	0.0	1053.0	COG0841@1|root,COG0841@2|Bacteria,46UEW@74201|Verrucomicrobia,2IV6M@203494|Verrucomicrobiae	2|Bacteria	V	AcrB/AcrD/AcrF family	acrD	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
CMS1_k127_3499990_7	1282876.BAOK01000001_gene2458	6.636e-64	233.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,2TRSC@28211|Alphaproteobacteria,4BQQP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_3499990_3	583355.Caka_0772	4.743e-127	421.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,46SH2@74201|Verrucomicrobia,3K7MN@414999|Opitutae	414999|Opitutae	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
CMS1_k127_3499990_11	583355.Caka_1753	1.919e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia,3K9NK@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3499990_16	583355.Caka_1754	1.837e-12	77.0	COG5662@1|root,COG5662@2|Bacteria,46VJ8@74201|Verrucomicrobia,3K9W5@414999|Opitutae	414999|Opitutae	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3499990_6	794903.OPIT5_28840	5.253e-75	265.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,3K7CJ@414999|Opitutae	414999|Opitutae	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
CMS1_k127_3499990_12	382464.ABSI01000010_gene3586	9.62e-31	132.0	COG4137@1|root,COG4137@2|Bacteria,46T0T@74201|Verrucomicrobia,2IUQ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_3499990_10	641491.DND132_3111	1.826e-47	179.0	COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,42QHH@68525|delta/epsilon subdivisions,2WMEX@28221|Deltaproteobacteria,2M9VT@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
CMS1_k127_3499990_2	452637.Oter_2360	1.823e-194	617.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,3K7TV@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_3499990_13	794903.OPIT5_02640	4.584e-26	111.0	COG0721@1|root,COG0721@2|Bacteria,46TA2@74201|Verrucomicrobia,3K8CA@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CMS1_k127_3515515_1	794903.OPIT5_07565	1.045e-105	360.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C,Glycos_transf_2
CMS1_k127_3515515_0	452637.Oter_3092	3.098e-263	831.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia,3K74J@414999|Opitutae	414999|Opitutae	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_3515515_2	452637.Oter_3226	1.942e-28	115.0	COG2272@1|root,COG2272@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS1_k127_3527951_1	583355.Caka_1147	2.814e-109	362.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia,3K7AD@414999|Opitutae	414999|Opitutae	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS1_k127_3527951_0	452637.Oter_2454	1.364e-206	658.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_3527951_2	762984.HMPREF9445_02064	3.962e-28	117.0	COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,2FPRJ@200643|Bacteroidia,4AKX3@815|Bacteroidaceae	976|Bacteroidetes	G	Kinase, PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_3540854_1	864051.BurJ1DRAFT_1285	6.165e-57	209.0	COG0500@1|root,COG2226@2|Bacteria,1N0NC@1224|Proteobacteria,2W3Y7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_3540854_0	313628.LNTAR_05166	1.316e-303	953.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS1_k127_3540854_2	583355.Caka_1063	7.998e-42	158.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,3K7PV@414999|Opitutae	414999|Opitutae	H	Protein-arginine kinase	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
CMS1_k127_354374_4	794903.OPIT5_03120	2.071e-47	176.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,3K7Y1@414999|Opitutae	414999|Opitutae	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_354374_0	485915.Dret_2373	7.149e-137	462.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PCY@68525|delta/epsilon subdivisions,2WJCR@28221|Deltaproteobacteria,2M8HZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	SMART chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K13487	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal
CMS1_k127_354374_2	583355.Caka_2568	1.003e-82	278.0	COG0377@1|root,COG0377@2|Bacteria,46U0Z@74201|Verrucomicrobia,3K7X8@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS1_k127_354374_1	583355.Caka_0726	8.304e-86	302.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,3K7I6@414999|Opitutae	414999|Opitutae	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
CMS1_k127_354374_3	583355.Caka_0725	9.915e-81	272.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,3K7Q1@414999|Opitutae	414999|Opitutae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_3589837_2	471854.Dfer_2397	1.74e-37	142.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,47J96@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
CMS1_k127_3589837_1	382464.ABSI01000005_gene1075	5.684e-93	310.0	COG0235@1|root,COG0235@2|Bacteria,46U10@74201|Verrucomicrobia,2IUBM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS1_k127_3589837_0	452637.Oter_1387	1.414e-242	760.0	COG4146@1|root,COG4146@2|Bacteria	2|Bacteria	S	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_3601820_1	314278.NB231_10158	4.913e-41	161.0	COG3637@1|root,COG3637@2|Bacteria,1R64D@1224|Proteobacteria,1S325@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS1_k127_3601820_0	1297742.A176_01721	3.785e-44	171.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42R1X@68525|delta/epsilon subdivisions,2WN2P@28221|Deltaproteobacteria,2Z322@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS1_k127_3609776_2	278957.ABEA03000195_gene480	4.016e-50	190.0	COG3934@1|root,COG3934@2|Bacteria,46Y9F@74201|Verrucomicrobia,3K960@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3609776_3	794903.OPIT5_26745	5.558e-29	126.0	2EMFU@1|root,33F4J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
CMS1_k127_3609776_0	278957.ABEA03000157_gene656	1.371e-154	498.0	COG0156@1|root,COG0156@2|Bacteria,46TFY@74201|Verrucomicrobia,3K7SB@414999|Opitutae	414999|Opitutae	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_3609776_1	794903.OPIT5_27185	6.62e-57	205.0	COG0847@1|root,COG0847@2|Bacteria,46VEF@74201|Verrucomicrobia,3K7YC@414999|Opitutae	414999|Opitutae	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	-
CMS1_k127_3609776_4	794903.OPIT5_19895	2.388e-27	112.0	COG0327@1|root,COG0327@2|Bacteria,46U5H@74201|Verrucomicrobia,3K7NT@414999|Opitutae	414999|Opitutae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS1_k127_361041_3	1347342.BN863_30860	1.787e-29	123.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11,Cellulase
CMS1_k127_361041_2	926550.CLDAP_18850	2.216e-151	488.0	COG1448@1|root,COG1448@2|Bacteria	2|Bacteria	E	Aminotransferase	aspC	GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iPC815.YPO1410,iSFxv_1172.SFxv_1000	Aminotran_1_2
CMS1_k127_361041_1	382464.ABSI01000010_gene3639	3.482e-278	868.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia,2ITUF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS1_k127_361041_0	667014.Thein_0257	0.0	1178.0	COG0458@1|root,COG0458@2|Bacteria,2GH37@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	EF	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_3629356_3	391613.RTM1035_01385	5.284e-109	355.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2TS3I@28211|Alphaproteobacteria,46RED@74030|Roseovarius	28211|Alphaproteobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_5
CMS1_k127_3629356_1	391613.RTM1035_01380	3.258e-145	469.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,46NCT@74030|Roseovarius	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_3629356_0	391616.OA238_c47390	7.817e-232	717.0	COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,2TTKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide	amiE	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_3629356_2	1305735.JAFT01000004_gene233	7.526e-120	388.0	COG0410@1|root,COG0410@2|Bacteria,1N01B@1224|Proteobacteria,2U1WJ@28211|Alphaproteobacteria,2PFFB@252301|Oceanicola	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
CMS1_k127_3629356_4	1305735.JAFT01000004_gene232	2.367e-13	70.0	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2TSDN@28211|Alphaproteobacteria,2PFWG@252301|Oceanicola	28211|Alphaproteobacteria	S	ABC transporter	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_3632061_2	332101.JIBU02000025_gene3210	7.209e-18	92.0	COG2836@1|root,COG2836@2|Bacteria,1VXKF@1239|Firmicutes,24ERT@186801|Clostridia,36HRG@31979|Clostridiaceae	186801|Clostridia	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS1_k127_3632061_1	504472.Slin_5746	5.412e-32	137.0	COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,47KQ2@768503|Cytophagia	976|Bacteroidetes	KT	PFAM LytTr DNA-binding region	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
CMS1_k127_3632061_0	583355.Caka_2867	2.321e-63	236.0	COG1295@1|root,COG1295@2|Bacteria,46USV@74201|Verrucomicrobia,3K77Z@414999|Opitutae	414999|Opitutae	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS1_k127_3644282_3	1121377.KB906400_gene1263	1.884e-30	123.0	2ED10@1|root,336XY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3644282_0	439235.Dalk_5049	1.704e-104	349.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria,2MK22@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_3644282_2	1121918.ARWE01000001_gene9	5.464e-36	141.0	arCOG08935@1|root,32Z08@2|Bacteria,1NC5T@1224|Proteobacteria,42XQ1@68525|delta/epsilon subdivisions,2X6PR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3644282_1	251229.Chro_3389	5.596e-47	176.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
CMS1_k127_3654004_1	439235.Dalk_0222	3.489e-87	293.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,42MH3@68525|delta/epsilon subdivisions,2WJAA@28221|Deltaproteobacteria,2MIWU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	LAO AO transport system	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS1_k127_3654004_0	583355.Caka_2437	3.367e-112	379.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46V4D@74201|Verrucomicrobia,3K7PF@414999|Opitutae	414999|Opitutae	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
CMS1_k127_3658705_5	290317.Cpha266_1157	5.003e-56	201.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
CMS1_k127_3658705_0	880073.Calab_3212	4.599e-249	787.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS1_k127_3658705_6	583355.Caka_2644	3.72e-45	174.0	2BXAM@1|root,2ZPRA@2|Bacteria,46VTF@74201|Verrucomicrobia,3K81N@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3658705_2	1242864.D187_009270	1.175e-104	349.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42UAF@68525|delta/epsilon subdivisions,2WQGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_3658705_9	861299.J421_1811	0.0009028	47.0	2A7X1@1|root,33FAX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3658705_4	382464.ABSI01000012_gene2078	2.117e-58	210.0	COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,2IU9Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Guanylate kinase homologues.	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS1_k127_3658705_3	452637.Oter_3682	4.844e-102	342.0	COG0483@1|root,COG0483@2|Bacteria,46UKW@74201|Verrucomicrobia,3K7E2@414999|Opitutae	414999|Opitutae	G	inositol monophosphate 1-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3658705_1	583355.Caka_1376	3.962e-119	392.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46UY4@74201|Verrucomicrobia,3K7AN@414999|Opitutae	414999|Opitutae	K	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
CMS1_k127_3658705_7	583355.Caka_2329	3.386e-24	107.0	COG1386@1|root,COG1386@2|Bacteria,46V9G@74201|Verrucomicrobia,3K7RR@414999|Opitutae	414999|Opitutae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS1_k127_365998_2	1191523.MROS_2327	9.54e-71	246.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	uxaC	GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528	UxaC
CMS1_k127_365998_1	1124780.ANNU01000071_gene1021	1.786e-155	503.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
CMS1_k127_365998_0	1168289.AJKI01000004_gene2995	5.95e-255	818.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FNT8@200643|Bacteroidia,3XM0W@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_365998_3	349741.Amuc_1623	6.111e-38	145.0	COG0621@1|root,COG0621@2|Bacteria,46S5U@74201|Verrucomicrobia,2ITS9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Uncharacterized protein family UPF0004	-	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_3669681_1	583355.Caka_1520	1.083e-65	233.0	COG0483@1|root,COG0483@2|Bacteria,46VJG@74201|Verrucomicrobia,3K83G@414999|Opitutae	414999|Opitutae	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_3669681_0	583355.Caka_0749	1.11e-179	574.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia,3K7P3@414999|Opitutae	414999|Opitutae	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_3669681_2	583355.Caka_0748	2.654e-63	220.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia,3K7IH@414999|Opitutae	414999|Opitutae	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_3687218_0	1408473.JHXO01000002_gene3925	4.613e-223	719.0	COG3250@1|root,COG3250@2|Bacteria,4NEP8@976|Bacteroidetes,2FMRW@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_3687218_2	583355.Caka_2979	5.323e-34	134.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,3K87I@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS1_k127_3687218_4	583355.Caka_2978	1.405e-09	61.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,3K8DB@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS1_k127_3687218_3	882.DVU_2572	7.4e-11	65.0	COG1918@1|root,COG1918@2|Bacteria,1P8DM@1224|Proteobacteria,42V0G@68525|delta/epsilon subdivisions,2WR9N@28221|Deltaproteobacteria,2MD3Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS1_k127_3687218_1	1298593.TOL_3291	8.485e-43	176.0	COG4774@1|root,COG4774@2|Bacteria,1QVD5@1224|Proteobacteria,1T2BR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_3687757_7	794903.OPIT5_19935	5.944e-109	361.0	COG0285@1|root,COG0285@2|Bacteria,46UIC@74201|Verrucomicrobia,3K7F0@414999|Opitutae	414999|Opitutae	H	Belongs to the folylpolyglutamate synthase family	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CMS1_k127_3687757_13	583355.Caka_1972	1.791e-50	188.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,3K7XA@414999|Opitutae	414999|Opitutae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3687757_9	1121445.ATUZ01000016_gene2596	2.564e-88	308.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2M94B@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_3687757_11	526222.Desal_1925	2.251e-79	274.0	COG2227@1|root,COG2227@2|Bacteria,1QYHT@1224|Proteobacteria,43A31@68525|delta/epsilon subdivisions,2X37X@28221|Deltaproteobacteria,2MCT6@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_3687757_17	583355.Caka_1274	2.062e-27	113.0	COG0211@1|root,COG0211@2|Bacteria,46X4Y@74201|Verrucomicrobia,3K8A7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS1_k127_3687757_14	794903.OPIT5_03435	2.664e-37	142.0	COG0261@1|root,COG0261@2|Bacteria,46VNZ@74201|Verrucomicrobia,3K87S@414999|Opitutae	414999|Opitutae	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS1_k127_3687757_1	452637.Oter_2743	0.0	1077.0	COG0726@1|root,COG0726@2|Bacteria,46UEB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolase family 9	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
CMS1_k127_3687757_6	452637.Oter_2742	1.221e-131	435.0	COG2942@1|root,COG2942@2|Bacteria,46U8G@74201|Verrucomicrobia,3K86A@414999|Opitutae	414999|Opitutae	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CMS1_k127_3687757_12	583355.Caka_1946	1.333e-51	193.0	COG1652@1|root,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_3687757_8	278957.ABEA03000135_gene1744	6.667e-108	359.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia,3K7IY@414999|Opitutae	414999|Opitutae	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS1_k127_3687757_16	366394.Smed_1020	1.428e-28	118.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,4BESE@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS1_k127_3687757_5	583355.Caka_1407	2.492e-179	574.0	COG0064@1|root,COG0064@2|Bacteria,46S5X@74201|Verrucomicrobia,3K7TB@414999|Opitutae	414999|Opitutae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_3687757_10	583355.Caka_1151	2.175e-79	275.0	COG0167@1|root,COG0167@2|Bacteria,46UMV@74201|Verrucomicrobia,3K92M@414999|Opitutae	414999|Opitutae	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_3687757_3	349741.Amuc_2034	2.713e-214	675.0	COG5016@1|root,COG5016@2|Bacteria,46UNW@74201|Verrucomicrobia,2IWQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	HMGL-like	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
CMS1_k127_3687757_2	583355.Caka_2572	1.148e-219	688.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia,3K7HM@414999|Opitutae	414999|Opitutae	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_3687757_4	478741.JAFS01000001_gene1219	1.097e-180	580.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,37FY5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_3687757_15	583355.Caka_0807	2.567e-29	131.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
CMS1_k127_3687757_0	583355.Caka_2519	0.0	1221.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,3K7A5@414999|Opitutae	414999|Opitutae	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_3741810_5	1121324.CLIT_23c00850	2.835e-05	50.0	COG2165@1|root,COG2165@2|Bacteria,1VK8F@1239|Firmicutes,24UDT@186801|Clostridia	186801|Clostridia	NU	prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl
CMS1_k127_3741810_3	316067.Geob_2527	4.865e-103	340.0	COG2000@1|root,COG2000@2|Bacteria,1NU4F@1224|Proteobacteria	1224|Proteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
CMS1_k127_3741810_1	269796.Rru_A1067	7.547e-119	386.0	COG0378@1|root,COG0378@2|Bacteria	2|Bacteria	KO	nickel cation binding	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
CMS1_k127_3741810_2	316067.Geob_2524	3.703e-114	373.0	COG1136@1|root,COG1136@2|Bacteria,1PXKV@1224|Proteobacteria,42PI6@68525|delta/epsilon subdivisions,2WJT8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_3741810_0	1268237.G114_02434	6.734e-279	874.0	COG2942@1|root,COG2942@2|Bacteria,1R8S3@1224|Proteobacteria,1SJIY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3741810_4	1268237.G114_02429	1.32e-90	303.0	COG0693@1|root,COG0693@2|Bacteria,1QTGZ@1224|Proteobacteria,1SVZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS1_k127_3748585_1	1232410.KI421413_gene566	1.795e-47	178.0	COG2184@1|root,COG2184@2|Bacteria,1QREW@1224|Proteobacteria,43B8J@68525|delta/epsilon subdivisions	1224|Proteobacteria	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
CMS1_k127_3748585_5	156889.Mmc1_2575	0.0006968	44.0	COG3077@1|root,COG3077@2|Bacteria	2|Bacteria	L	bacterial-type proximal promoter sequence-specific DNA binding	relB1	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
CMS1_k127_3748585_2	525146.Ddes_0227	1.485e-16	86.0	2E3TC@1|root,32YQV@2|Bacteria,1N7A9@1224|Proteobacteria,42VBE@68525|delta/epsilon subdivisions,2WSGC@28221|Deltaproteobacteria,2MCMR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	copG family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3748585_3	1122962.AULH01000005_gene2642	9.713e-15	76.0	COG2929@1|root,COG2929@2|Bacteria,1MZKJ@1224|Proteobacteria,2UDS0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_3748585_4	573370.DMR_39320	0.0004809	47.0	2CFD1@1|root,2ZMI9@2|Bacteria,1P8BR@1224|Proteobacteria,4324N@68525|delta/epsilon subdivisions,2WYA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
CMS1_k127_3748585_0	1183438.GKIL_2871	3.478e-186	598.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria	1117|Cyanobacteria	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
CMS1_k127_3750954_1	886293.Sinac_1993	1.347e-32	127.0	COG5609@1|root,COG5609@2|Bacteria,2J0WE@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
CMS1_k127_3750954_0	1396418.BATQ01000056_gene185	1.462e-121	409.0	COG0612@1|root,COG0612@2|Bacteria,46UTT@74201|Verrucomicrobia,2ITM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_3755144_0	264462.Bd1081	1.153e-82	298.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MZX@68525|delta/epsilon subdivisions,2MTNJ@213481|Bdellovibrionales,2WMCT@28221|Deltaproteobacteria	213481|Bdellovibrionales	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
CMS1_k127_3760061_0	754035.Mesau_06004	9.332e-102	339.0	COG1475@1|root,COG1475@2|Bacteria,1MUE5@1224|Proteobacteria,2TTN0@28211|Alphaproteobacteria,43MKV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	RepB plasmid partitioning protein	-	-	-	-	-	-	-	-	-	-	-	-	ParBc,RepB
CMS1_k127_3760061_1	498211.CJA_1211	1.159e-63	220.0	COG2184@1|root,COG2184@2|Bacteria,1RAVF@1224|Proteobacteria,1S5YI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Mobile mystery protein B	-	-	-	-	-	-	-	-	-	-	-	-	Fic
CMS1_k127_3762923_1	313612.L8106_17742	6.464e-122	418.0	COG5360@1|root,COG5360@2|Bacteria,1G4V0@1117|Cyanobacteria	1117|Cyanobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
CMS1_k127_3762923_2	278957.ABEA03000085_gene2575	2.704e-72	253.0	COG1792@1|root,COG1792@2|Bacteria,46T2J@74201|Verrucomicrobia,3K7Q6@414999|Opitutae	414999|Opitutae	M	shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_3762923_0	583355.Caka_1486	2.231e-172	549.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,3K7RX@414999|Opitutae	414999|Opitutae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_3771005_0	382464.ABSI01000013_gene1703	8.374e-309	962.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,46TG1@74201|Verrucomicrobia,2ITWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS1_k127_3771005_3	1403819.BATR01000130_gene4578	1.559e-19	94.0	COG0735@1|root,COG0735@2|Bacteria,46YG1@74201|Verrucomicrobia,2IUDH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferric uptake regulator family	-	-	-	-	-	-	-	-	-	-	-	-	FUR
CMS1_k127_3771005_4	1408813.AYMG01000001_gene3486	2.233e-16	85.0	COG2259@1|root,COG2259@2|Bacteria,4NTM8@976|Bacteroidetes,1ITB2@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_3771005_2	382464.ABSI01000005_gene1332	1.285e-61	215.0	COG0219@1|root,COG0219@2|Bacteria,46SYZ@74201|Verrucomicrobia,2IUCK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_3771005_1	583355.Caka_0886	3.225e-86	313.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_3771818_0	264462.Bd1081	2.733e-83	301.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MZX@68525|delta/epsilon subdivisions,2MTNJ@213481|Bdellovibrionales,2WMCT@28221|Deltaproteobacteria	213481|Bdellovibrionales	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
CMS1_k127_3771818_1	452637.Oter_2853	2.551e-55	199.0	COG0258@1|root,COG0258@2|Bacteria,46SWB@74201|Verrucomicrobia,3K7JE@414999|Opitutae	414999|Opitutae	L	5'-3' exonuclease	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
CMS1_k127_3776522_5	452637.Oter_2353	5.383e-27	114.0	COG0285@1|root,COG0285@2|Bacteria,46UIC@74201|Verrucomicrobia,3K7F0@414999|Opitutae	414999|Opitutae	H	Belongs to the folylpolyglutamate synthase family	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CMS1_k127_3776522_3	583355.Caka_1575	1.176e-34	139.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,3K88H@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS1_k127_3776522_1	1403819.BATR01000092_gene2749	1.536e-144	466.0	COG0722@1|root,COG0722@2|Bacteria,46UK5@74201|Verrucomicrobia,2ITP2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	DAHP synthetase I family	-	-	-	-	-	-	-	-	-	-	-	-	DAHP_synth_1
CMS1_k127_3776522_0	382464.ABSI01000010_gene3393	9.166e-148	482.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_3776522_2	56780.SYN_00036	3.446e-96	329.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,42PT6@68525|delta/epsilon subdivisions,2WK6I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_3776522_4	582402.Hbal_2834	1.257e-28	127.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,43WVB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	K -dependent Na Ca	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_3789325_3	583355.Caka_2532	3.081e-68	234.0	COG0178@1|root,COG0178@2|Bacteria,46SEB@74201|Verrucomicrobia,3K7R9@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_3789325_2	237368.SCABRO_01129	2.05e-132	432.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS1_k127_3789325_5	420247.Msm_0137	1.165e-16	94.0	COG1413@1|root,arCOG02966@2157|Archaea	2157|Archaea	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_3789325_0	583355.Caka_2413	2.458e-204	642.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,3K7AT@414999|Opitutae	414999|Opitutae	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS1_k127_3789325_4	583355.Caka_2833	9.215e-38	148.0	COG1528@1|root,COG1528@2|Bacteria,46VSW@74201|Verrucomicrobia,3K89S@414999|Opitutae	414999|Opitutae	P	Ferritin-like domain	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CMS1_k127_3789325_1	452637.Oter_4602	1.889e-141	464.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,3K7FW@414999|Opitutae	414999|Opitutae	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_3798569_2	452637.Oter_0207	9.846e-148	476.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_3798569_5	382464.ABSI01000013_gene1597	1.713e-93	314.0	COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia,2ITSS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_3798569_12	382464.ABSI01000011_gene2650	9.229e-43	159.0	COG0099@1|root,COG0099@2|Bacteria,46VYP@74201|Verrucomicrobia,2IUGG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS1_k127_3798569_9	583355.Caka_1667	1.199e-66	232.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia,3K82X@414999|Opitutae	414999|Opitutae	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS1_k127_3798569_7	583355.Caka_1666	6.816e-85	285.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,3K7K0@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS1_k127_3798569_1	583355.Caka_1665	6.59e-163	518.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,3K7N7@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_3798569_13	382464.ABSI01000011_gene2646	7.319e-40	153.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,2IUE5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS1_k127_3798569_16	278957.ABEA03000152_gene4081	2.799e-10	64.0	29TM9@1|root,30EUT@2|Bacteria,46XC0@74201|Verrucomicrobia,3K8GF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3798569_0	452637.Oter_0192	3.372e-235	738.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS1_k127_3798569_6	1169143.KB911037_gene3776	2.66e-85	298.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2VNDX@28216|Betaproteobacteria,1K0TY@119060|Burkholderiaceae	28216|Betaproteobacteria	V	beta-lactamase	ampC	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
CMS1_k127_3798569_3	583355.Caka_2357	9.02e-131	430.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,3K7N3@414999|Opitutae	414999|Opitutae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS1_k127_3798569_11	1160707.AJIK01000006_gene986	1.525e-50	184.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,4HJ2V@91061|Bacilli,26F7S@186818|Planococcaceae	91061|Bacilli	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS1_k127_3798569_10	583355.Caka_0209	1.373e-66	235.0	COG0563@1|root,COG0563@2|Bacteria,46UF6@74201|Verrucomicrobia,3K7G4@414999|Opitutae	414999|Opitutae	F	adenylate kinase	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
CMS1_k127_3798569_4	583355.Caka_2020	6.853e-120	405.0	COG0815@1|root,COG0815@2|Bacteria,46SPW@74201|Verrucomicrobia,3K74H@414999|Opitutae	414999|Opitutae	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS1_k127_3798569_8	452637.Oter_1911	1.865e-82	284.0	COG0084@1|root,COG0084@2|Bacteria,46U6H@74201|Verrucomicrobia,3K7YI@414999|Opitutae	414999|Opitutae	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS1_k127_3798569_14	794903.OPIT5_25080	3.896e-27	117.0	COG1406@1|root,COG1406@2|Bacteria,46VWI@74201|Verrucomicrobia,3K86V@414999|Opitutae	414999|Opitutae	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
CMS1_k127_3798569_15	935557.ATYB01000008_gene5360	1.028e-13	74.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2TW1J@28211|Alphaproteobacteria,4B7HQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,Response_reg
CMS1_k127_3801854_0	880072.Desac_1787	1.043e-132	431.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,42MX4@68525|delta/epsilon subdivisions,2WKUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ATPase associated with various cellular activities	-	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C
CMS1_k127_3801854_3	706587.Desti_4947	3.4e-09	62.0	296XC@1|root,2ZU61@2|Bacteria,1P6ZE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3801854_2	706587.Desti_4948	2.427e-13	71.0	297PT@1|root,2ZUWQ@2|Bacteria,1PBQK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3801854_1	706587.Desti_4949	1.399e-39	152.0	COG0154@1|root,COG0154@2|Bacteria,1MZSF@1224|Proteobacteria,4305X@68525|delta/epsilon subdivisions,2WV81@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	protein, GvpL GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
CMS1_k127_3802303_3	267608.RSc1499	0.0001291	46.0	COG3751@1|root,COG3751@2|Bacteria,1N2TX@1224|Proteobacteria	1224|Proteobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
CMS1_k127_3802303_1	330214.NIDE3334	1.36e-63	222.0	COG3751@1|root,COG3751@2|Bacteria	2|Bacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
CMS1_k127_3802303_2	330214.NIDE3327	1.055e-44	168.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS1_k127_3802303_0	330214.NIDE3335	3.828e-119	386.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01421,ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
CMS1_k127_3805386_2	1128912.GMES_1058	7.674e-08	53.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,1RZDR@1236|Gammaproteobacteria,4668V@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	SH3 domain (SH3b1 type)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,SH3_6,SH3_7
CMS1_k127_3805386_0	766499.C357_14374	1.383e-66	234.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2TV0F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	ftrB	-	-	ko:K13642	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_3805386_1	1144275.COCOR_07231	1.931e-18	93.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX4C@1224|Proteobacteria,43BWW@68525|delta/epsilon subdivisions,2X77N@28221|Deltaproteobacteria,2YXG1@29|Myxococcales	28221|Deltaproteobacteria	DEZ	TIGRFAM cysteine-rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS1_k127_3813258_1	1192868.CAIU01000008_gene937	5.486e-15	76.0	COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria,43KMC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CMS1_k127_3813258_0	640513.Entas_2628	4.236e-30	131.0	COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,1NEAE@1224|Proteobacteria	1224|Proteobacteria	V	N-acetylmuramoyl-L-alanine amidase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS1_k127_3813258_2	439375.Oant_1523	5.548e-06	51.0	2DEFV@1|root,2ZMV1@2|Bacteria,1P428@1224|Proteobacteria,2UY04@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3824160_0	489825.LYNGBM3L_63420	8.326e-319	1026.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase
CMS1_k127_3824160_1	1280666.ATVS01000001_gene3174	6.691e-21	92.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,4BW8D@830|Butyrivibrio	186801|Clostridia	G	PEP-utilising enzyme, TIM barrel domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_3826775_7	1128427.KB904821_gene1968	6.717e-63	225.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_3826775_5	583355.Caka_1791	1.336e-90	307.0	COG0196@1|root,COG0196@2|Bacteria,46UCC@74201|Verrucomicrobia,3K7G1@414999|Opitutae	414999|Opitutae	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS1_k127_3826775_2	583355.Caka_0684	5.99e-212	679.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia,3K7QQ@414999|Opitutae	414999|Opitutae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_3826775_9	583355.Caka_2855	3.412e-47	176.0	COG0233@1|root,COG0233@2|Bacteria,46SVT@74201|Verrucomicrobia,3K7EG@414999|Opitutae	414999|Opitutae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS1_k127_3826775_0	522772.Dacet_2595	0.0	1011.0	COG1166@1|root,COG1166@2|Bacteria,2GF9G@200930|Deferribacteres	200930|Deferribacteres	H	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CMS1_k127_3826775_1	522772.Dacet_2596	2.727e-227	707.0	COG1748@1|root,COG1748@2|Bacteria,2GEMV@200930|Deferribacteres	200930|Deferribacteres	C	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS1_k127_3826775_8	1279017.AQYJ01000028_gene2525	6.655e-49	186.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_3826775_3	519989.ECTPHS_04523	4.068e-136	443.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,1RP8C@1236|Gammaproteobacteria,1WY12@135613|Chromatiales	135613|Chromatiales	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	-	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
CMS1_k127_3826775_4	522772.Dacet_2598	2.654e-104	347.0	COG0010@1|root,COG0010@2|Bacteria,2GFS4@200930|Deferribacteres	200930|Deferribacteres	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS1_k127_3826775_10	1121346.KB899826_gene420	1.845e-11	77.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,4HARD@91061|Bacilli,26RWZ@186822|Paenibacillaceae	91061|Bacilli	K	GntR family transcriptional regulator	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
CMS1_k127_3826775_6	398512.JQKC01000103_gene2699	1.63e-73	255.0	COG0524@1|root,COG0524@2|Bacteria,1UYHM@1239|Firmicutes,24DYS@186801|Clostridia,3WIP7@541000|Ruminococcaceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_3829376_0	381666.H16_A2216	2.918e-78	270.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2VTNF@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
CMS1_k127_3835248_6	985255.APHJ01000029_gene2502	0.0002582	46.0	COG1787@1|root,COG1787@2|Bacteria,4PP6M@976|Bacteroidetes	976|Bacteroidetes	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3835248_3	391587.KAOT1_21941	2.217e-29	130.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_3835248_1	452637.Oter_1021	1.086e-87	307.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_4,Chlorophyllase2,PAF-AH_p_II
CMS1_k127_3835248_4	485918.Cpin_4892	1.257e-16	82.0	2DBYN@1|root,2ZBWH@2|Bacteria,4NIPQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3835248_2	485918.Cpin_4892	2.594e-33	133.0	2DBYN@1|root,2ZBWH@2|Bacteria,4NIPQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3835248_5	760192.Halhy_5492	4.551e-13	72.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,Beta-lactamase
CMS1_k127_3835248_0	204669.Acid345_4152	1.644e-234	752.0	COG1472@1|root,COG1472@2|Bacteria,3Y2YR@57723|Acidobacteria,2JHNP@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM glycoside hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_3842138_0	697281.Mahau_1132	2.295e-81	287.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_3842138_1	794903.OPIT5_27200	4.329e-14	74.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_3852905_8	278957.ABEA03000019_gene1935	1.803e-90	306.0	COG1639@1|root,COG1639@2|Bacteria,46WBU@74201|Verrucomicrobia,3K7UG@414999|Opitutae	414999|Opitutae	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_3852905_4	382464.ABSI01000005_gene968	6.135e-128	438.0	COG0475@1|root,COG0475@2|Bacteria,46U4K@74201|Verrucomicrobia,2IV1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
CMS1_k127_3852905_3	382464.ABSI01000014_gene1454	1.541e-134	441.0	COG0477@1|root,COG2814@2|Bacteria,46UQQ@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	MFS_1 like family	-	-	-	ko:K03291	-	-	-	-	ko00000,ko02000	2.A.1.20	-	-	MFS_1
CMS1_k127_3852905_15	1088868.CIN_16260	2.027e-28	124.0	COG1442@1|root,COG1442@2|Bacteria,1MXIY@1224|Proteobacteria,2U52Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422,Glyco_transf_8
CMS1_k127_3852905_13	382464.ABSI01000005_gene1208	1.754e-34	142.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia,2IUHD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS1_k127_3852905_0	1396418.BATQ01000163_gene2005	4.59e-173	564.0	COG4166@1|root,COG4166@2|Bacteria,46UFF@74201|Verrucomicrobia,2ITVT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS1_k127_3852905_6	1403819.BATR01000191_gene6507	2.614e-119	393.0	COG0444@1|root,COG0444@2|Bacteria,46YTM@74201|Verrucomicrobia,2IU2Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_3852905_1	278957.ABEA03000180_gene2029	7.032e-151	508.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,3K7JV@414999|Opitutae	414999|Opitutae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
CMS1_k127_3852905_11	583355.Caka_1451	6.25e-41	158.0	COG0237@1|root,COG0237@2|Bacteria,46T2P@74201|Verrucomicrobia,3K83B@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS1_k127_3852905_2	931276.Cspa_c18620	1.383e-137	459.0	COG2730@1|root,COG2730@2|Bacteria,1TQHH@1239|Firmicutes,24BQU@186801|Clostridia,36HAF@31979|Clostridiaceae	186801|Clostridia	G	Glycoside hydrolase family 44	celA2	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Dockerin_1,Glyco_hydro_44,PKD
CMS1_k127_3852905_12	583355.Caka_2946	1.424e-40	155.0	COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,3K7YM@414999|Opitutae	414999|Opitutae	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
CMS1_k127_3852905_10	1121935.AQXX01000117_gene5104	8.313e-42	160.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,1SQYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3852905_7	794903.OPIT5_04180	5.599e-106	351.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,3K7F5@414999|Opitutae	414999|Opitutae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS1_k127_3852905_16	583355.Caka_0742	3.84e-07	58.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	pilV-1	-	-	ko:K02671,ko:K02681	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
CMS1_k127_3852905_14	583355.Caka_0743	2.616e-30	130.0	28VAJ@1|root,2ZHDC@2|Bacteria,46WPS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3852905_5	583355.Caka_0744	1.139e-127	436.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3852905_9	1403819.BATR01000191_gene6506	8.447e-46	169.0	COG4608@1|root,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,2ITPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_3888_0	1089552.KI911559_gene2519	3.791e-83	287.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria,2JRCB@204441|Rhodospirillales	204441|Rhodospirillales	S	Elongator protein 3, MiaB family, Radical SAM	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS1_k127_3890175_0	1288494.EBAPG3_23150	1.634e-11	76.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,3744R@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_3890175_1	1122207.MUS1_09570	2.875e-07	54.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria,1XMSA@135619|Oceanospirillales	135619|Oceanospirillales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS1_k127_3915811_7	1304874.JAFY01000001_gene2556	9.722e-108	380.0	COG2984@1|root,COG2984@2|Bacteria,3TBSS@508458|Synergistetes	508458|Synergistetes	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
CMS1_k127_3915811_2	631362.Thi970DRAFT_01699	7.386e-154	514.0	COG2172@1|root,COG2208@1|root,COG2972@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG2972@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1WXGP@135613|Chromatiales	135613|Chromatiales	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K01079,ko:K07315	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	GAF,HAMP,SpoIIE,dCache_1
CMS1_k127_3915811_10	1120985.AUMI01000017_gene2581	3.96e-82	285.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes	1239|Firmicutes	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_3915811_22	243161.TC_0707	1.387e-07	57.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS1_k127_3915811_24	452637.Oter_2738	0.000888	49.0	COG1214@1|root,COG1214@2|Bacteria,46WS7@74201|Verrucomicrobia,3K8JH@414999|Opitutae	414999|Opitutae	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_3915811_21	382464.ABSI01000005_gene1327	3.32e-12	70.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3915811_14	794903.OPIT5_05380	6.184e-36	143.0	COG2885@1|root,COG2885@2|Bacteria,46T4D@74201|Verrucomicrobia,3K879@414999|Opitutae	414999|Opitutae	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS1_k127_3915811_5	583355.Caka_0686	9.442e-115	385.0	COG1169@1|root,COG1169@2|Bacteria,46TTI@74201|Verrucomicrobia,3K7NU@414999|Opitutae	414999|Opitutae	HQ	Isochorismate synthase	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
CMS1_k127_3915811_20	387092.NIS_0197	8.677e-22	104.0	COG0551@1|root,COG0551@2|Bacteria,1RJ5B@1224|Proteobacteria,42XHH@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Protein of unknown function (DUF2726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726,zf-C4_Topoisom
CMS1_k127_3915811_1	794903.OPIT5_19015	2.345e-217	685.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,3K783@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
CMS1_k127_3915811_19	153721.MYP_3343	2.146e-23	104.0	COG1246@1|root,COG1246@2|Bacteria,4NVX0@976|Bacteroidetes,47SE9@768503|Cytophagia	976|Bacteroidetes	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_3915811_12	1123508.JH636448_gene7514	8.669e-65	234.0	COG0689@1|root,COG2931@1|root,COG3291@1|root,COG4932@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,2J503@203682|Planctomycetes	203682|Planctomycetes	J	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4465,Dockerin_1
CMS1_k127_3915811_11	1131812.JQMS01000001_gene2738	3.826e-67	245.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,1HZVC@117743|Flavobacteriia,2NUXF@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF1624,DUF418
CMS1_k127_3915811_9	1396141.BATP01000021_gene170	3.736e-95	336.0	COG4206@1|root,COG4206@2|Bacteria,46Z6S@74201|Verrucomicrobia,2IWPX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_3915811_16	1304888.ATWF01000001_gene1910	2.872e-30	136.0	2DMBB@1|root,32GIQ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4465,PKD_3,VPEP
CMS1_k127_3915811_18	56107.Cylst_5225	1.842e-28	128.0	29WGE@1|root,30I2I@2|Bacteria,1GFWI@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3915811_15	926692.AZYG01000036_gene2555	1.823e-35	148.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,3WAIV@53433|Halanaerobiales	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_3915811_4	452637.Oter_2420	8.792e-115	377.0	COG0601@1|root,COG0601@2|Bacteria,46SJN@74201|Verrucomicrobia,3K7V9@414999|Opitutae	414999|Opitutae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS1_k127_3915811_23	1238182.C882_3733	0.0008114	52.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2JQ9G@204441|Rhodospirillales	204441|Rhodospirillales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_3915811_13	509191.AEDB02000108_gene1676	2.431e-37	162.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_3915811_17	1396141.BATP01000062_gene4444	1.489e-28	134.0	COG1262@1|root,COG3794@1|root,COG1262@2|Bacteria,COG3794@2|Bacteria,46WEI@74201|Verrucomicrobia,2IVF7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_3915811_6	583355.Caka_2827	3.596e-109	360.0	COG2908@1|root,COG2908@2|Bacteria,46U19@74201|Verrucomicrobia,3K7GU@414999|Opitutae	414999|Opitutae	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_3915811_0	583355.Caka_2737	2.894e-256	823.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,46TSJ@74201|Verrucomicrobia,3K74S@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
CMS1_k127_3915811_8	583355.Caka_1947	8.996e-103	344.0	COG0604@1|root,COG0604@2|Bacteria,46VV3@74201|Verrucomicrobia,3K9E2@414999|Opitutae	414999|Opitutae	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3915811_3	234267.Acid_3825	2.501e-151	490.0	COG0531@1|root,COG0531@2|Bacteria,3Y6J9@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	-
CMS1_k127_3944589_3	583355.Caka_2291	1.289e-21	100.0	COG2165@1|root,COG2165@2|Bacteria,46XVX@74201|Verrucomicrobia,3K8F0@414999|Opitutae	414999|Opitutae	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_3944589_0	583355.Caka_2114	4.911e-55	203.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia,3K817@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS1_k127_3944589_2	1123320.KB889684_gene2304	5.871e-25	106.0	COG2350@1|root,COG2350@2|Bacteria,2GRVC@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS1_k127_3944589_1	517418.Ctha_0605	2.383e-33	133.0	COG0784@1|root,COG2198@1|root,COG3292@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,1FDBJ@1090|Chlorobi	1090|Chlorobi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg,dCache_3
CMS1_k127_3981735_0	583355.Caka_0927	9.714e-168	534.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,3K7MI@414999|Opitutae	414999|Opitutae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS1_k127_3981735_2	1121287.AUMU01000009_gene2173	2.876e-25	111.0	COG0545@1|root,COG0545@2|Bacteria,4NJKK@976|Bacteroidetes,1I0YI@117743|Flavobacteriia,3ZNYK@59732|Chryseobacterium	976|Bacteroidetes	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	fkpB	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS1_k127_3981735_1	382464.ABSI01000023_gene550	5.907e-136	439.0	COG0031@1|root,COG0031@2|Bacteria,46UMC@74201|Verrucomicrobia,2ITKD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_3987183_0	452637.Oter_3830	1.041e-141	458.0	COG0482@1|root,COG0482@2|Bacteria,46UNS@74201|Verrucomicrobia,3K74M@414999|Opitutae	414999|Opitutae	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS1_k127_3987183_1	593117.TGAM_0982	2.296e-20	107.0	COG5306@1|root,arCOG03264@1|root,arCOG06661@1|root,arCOG03264@2157|Archaea,arCOG03512@2157|Archaea,arCOG06661@2157|Archaea	2157|Archaea	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,DUF5122,Laminin_G_3,PEGA
CMS1_k127_3987183_2	1396418.BATQ01000012_gene4437	4.652e-20	97.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia,2ITIH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
CMS1_k127_3987413_3	1385935.N836_21945	6.744e-49	189.0	COG1322@1|root,COG1322@2|Bacteria,1GDJN@1117|Cyanobacteria	1117|Cyanobacteria	S	RmuC family	-	-	-	-	-	-	-	-	-	-	-	-	RmuC
CMS1_k127_3987413_5	459495.SPLC1_S200460	6.722e-33	141.0	COG0642@1|root,COG2205@2|Bacteria,1G3AM@1117|Cyanobacteria,1HA0Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
CMS1_k127_3987413_6	1123053.AUDG01000017_gene3341	1.431e-07	60.0	2CI6B@1|root,303H9@2|Bacteria,1N3RZ@1224|Proteobacteria,1S41V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3987413_1	382464.ABSI01000005_gene1143	5.73e-111	372.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,2IU74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_3987413_0	517418.Ctha_0585	1.76e-125	414.0	COG0577@1|root,COG0577@2|Bacteria,1FDSK@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_3987413_2	382464.ABSI01000005_gene1145	6.069e-97	323.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,2IUA4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3987413_4	382464.ABSI01000005_gene1146	5.868e-40	155.0	COG0845@1|root,COG0845@2|Bacteria,46U5P@74201|Verrucomicrobia,2IU9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS1_k127_4031235_0	1396141.BATP01000058_gene2050	2.517e-181	579.0	COG5297@1|root,COG5297@2|Bacteria,46XAP@74201|Verrucomicrobia,2IV7K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
CMS1_k127_4031235_1	243090.RB3417	3.166e-09	59.0	COG2755@1|root,COG2755@2|Bacteria,2IZBK@203682|Planctomycetes	203682|Planctomycetes	E	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase
CMS1_k127_4038350_6	1033806.HTIA_1483	1.108e-06	61.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,23XQF@183963|Halobacteria	183963|Halobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_4038350_1	608538.HTH_1738	5.458e-60	216.0	COG1180@1|root,COG1180@2|Bacteria,2G49Z@200783|Aquificae	200783|Aquificae	O	Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS1_k127_4038350_0	1500890.JQNL01000001_gene1168	4.852e-118	388.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,1RMIG@1236|Gammaproteobacteria,1X47C@135614|Xanthomonadales	135614|Xanthomonadales	C	potassium channel beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4038350_2	1121459.AQXE01000007_gene563	2.54e-56	203.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,42S18@68525|delta/epsilon subdivisions,2WN9J@28221|Deltaproteobacteria,2MAMV@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
CMS1_k127_4038350_5	794903.OPIT5_22035	3.556e-25	107.0	COG1758@1|root,COG1758@2|Bacteria,46T94@74201|Verrucomicrobia,3K8FM@414999|Opitutae	414999|Opitutae	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS1_k127_4038350_3	794903.OPIT5_22040	2.475e-42	160.0	COG0691@1|root,COG0691@2|Bacteria,46VG2@74201|Verrucomicrobia,3K83A@414999|Opitutae	414999|Opitutae	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS1_k127_4038350_4	583355.Caka_2338	3.577e-36	147.0	COG0553@1|root,COG0553@2|Bacteria,46UW7@74201|Verrucomicrobia,3K7NY@414999|Opitutae	414999|Opitutae	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
CMS1_k127_4042725_3	583355.Caka_1738	5.431e-111	363.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CMS1_k127_4042725_0	1121920.AUAU01000004_gene644	4e-323	998.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria	57723|Acidobacteria	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_4042725_4	583355.Caka_1740	3.195e-50	188.0	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
CMS1_k127_4042725_6	4513.MLOC_33843.1	0.0007555	45.0	COG0318@1|root,KOG1176@2759|Eukaryota,37NZS@33090|Viridiplantae,3G7PF@35493|Streptophyta,3M27U@4447|Liliopsida,3IFU8@38820|Poales	35493|Streptophyta	I	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4042725_5	583355.Caka_2679	7.248e-21	100.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	4.3.1.14	ko:K07107,ko:K18014	ko00310,map00310	-	R03030	RC00833	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
CMS1_k127_4042725_2	1203611.KB894545_gene361	3.472e-162	516.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia	976|Bacteroidetes	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CMS1_k127_4042725_1	945713.IALB_0026	4.509e-168	535.0	COG1830@1|root,COG1830@2|Bacteria	2|Bacteria	G	lyase activity	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
CMS1_k127_4066314_5	452637.Oter_2371	5.524e-85	289.0	COG1189@1|root,COG1189@2|Bacteria,46SM8@74201|Verrucomicrobia,3K7BI@414999|Opitutae	414999|Opitutae	J	S4 RNA-binding domain	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS1_k127_4066314_6	382464.ABSI01000002_gene4350	1.042e-26	114.0	COG2001@1|root,COG2001@2|Bacteria,46T5G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS1_k127_4066314_3	452637.Oter_2626	7.96e-90	309.0	COG0275@1|root,COG0275@2|Bacteria,46UYN@74201|Verrucomicrobia,3K74T@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS1_k127_4066314_8	452637.Oter_2627	0.0002033	49.0	2BX13@1|root,2ZS8Q@2|Bacteria,46WFM@74201|Verrucomicrobia,3K8DH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4066314_0	583355.Caka_3065	1.728e-170	554.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,3K799@414999|Opitutae	414999|Opitutae	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_4066314_1	278957.ABEA03000051_gene207	2.823e-163	530.0	COG0769@1|root,COG0769@2|Bacteria,46SGG@74201|Verrucomicrobia,3K7EA@414999|Opitutae	414999|Opitutae	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_4066314_4	452637.Oter_2630	1.719e-89	314.0	COG0770@1|root,COG0770@2|Bacteria,46UDV@74201|Verrucomicrobia,3K7ND@414999|Opitutae	414999|Opitutae	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_4066314_2	583355.Caka_3068	1.149e-138	450.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS1_k127_4066314_7	452637.Oter_2633	1.055e-23	105.0	COG0771@1|root,COG0771@2|Bacteria,46UT1@74201|Verrucomicrobia,3K78H@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_4071130_0	1537994.JQFW01000050_gene2382	7.786e-186	610.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,4662T@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_4071130_1	314287.GB2207_05839	2.66e-25	117.0	COG3765@1|root,COG3765@2|Bacteria,1MXGW@1224|Proteobacteria,1RPE4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	lipopolysaccharide biosynthesis protein	wzz	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
CMS1_k127_4079995_1	338966.Ppro_2148	9.46e-108	372.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria,43T50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
CMS1_k127_4079995_4	794903.OPIT5_19625	4.752e-71	248.0	COG4559@1|root,COG4559@2|Bacteria,46W2C@74201|Verrucomicrobia,3K8XY@414999|Opitutae	414999|Opitutae	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS1_k127_4079995_3	1197906.CAJQ02000021_gene4624	1.358e-83	289.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,3JRWV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_4079995_0	583355.Caka_1472	4.136e-119	394.0	COG0167@1|root,COG0167@2|Bacteria,46S5W@74201|Verrucomicrobia,3K7GG@414999|Opitutae	414999|Opitutae	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_4079995_2	583355.Caka_1390	2.177e-94	319.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia,3K77G@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
CMS1_k127_4079995_5	452637.Oter_2286	1.485e-50	186.0	COG0193@1|root,COG0193@2|Bacteria,46T09@74201|Verrucomicrobia,3K7ZI@414999|Opitutae	414999|Opitutae	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS1_k127_4079995_7	278957.ABEA03000041_gene2215	1.636e-15	79.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,3K8BM@414999|Opitutae	414999|Opitutae	J	Ribosomal protein S6	-	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS1_k127_4079995_6	583355.Caka_1586	2.457e-37	141.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS1_k127_4082999_1	1123277.KB893195_gene5699	9.183e-182	576.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,47J96@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
CMS1_k127_4082999_0	382464.ABSI01000005_gene1073	5.82e-246	773.0	COG1069@1|root,COG1069@2|Bacteria,46UI3@74201|Verrucomicrobia,2ITGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
CMS1_k127_4082999_2	794903.OPIT5_28235	1.702e-34	136.0	COG1609@1|root,COG1609@2|Bacteria,46UWC@74201|Verrucomicrobia,3K8PW@414999|Opitutae	414999|Opitutae	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI
CMS1_k127_4087586_1	794903.OPIT5_11750	1.079e-71	249.0	COG0325@1|root,COG0325@2|Bacteria,46SV2@74201|Verrucomicrobia,3K7XG@414999|Opitutae	414999|Opitutae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS1_k127_4087586_0	583355.Caka_0413	3.578e-129	419.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4087586_2	1125863.JAFN01000001_gene714	6.086e-10	64.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WQQK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_4090306_0	583355.Caka_1092	3.921e-111	368.0	COG0508@1|root,COG0508@2|Bacteria,46SD3@74201|Verrucomicrobia,3K7CM@414999|Opitutae	414999|Opitutae	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_4090306_1	583355.Caka_1093	5.787e-104	347.0	COG1249@1|root,COG1249@2|Bacteria,46SJE@74201|Verrucomicrobia,3K7MT@414999|Opitutae	414999|Opitutae	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_4096428_0	452637.Oter_2989	1.097e-165	550.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia,3K7Q7@414999|Opitutae	414999|Opitutae	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_4096428_5	583355.Caka_1130	1.026e-54	197.0	COG0537@1|root,COG0537@2|Bacteria,46T23@74201|Verrucomicrobia,3K81F@414999|Opitutae	414999|Opitutae	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
CMS1_k127_4096428_2	382464.ABSI01000021_gene370	9.06e-112	371.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia,2ITJX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	PhoH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhoH
CMS1_k127_4096428_1	583355.Caka_1132	1.59e-161	538.0	COG1480@1|root,COG1480@2|Bacteria,46TM6@74201|Verrucomicrobia,3K7BW@414999|Opitutae	414999|Opitutae	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
CMS1_k127_4096428_7	382464.ABSI01000021_gene368	7.652e-38	150.0	COG0319@1|root,COG0319@2|Bacteria,46WBN@74201|Verrucomicrobia,2IUS4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS1_k127_4096428_9	861299.J421_3777	1.173e-34	141.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS1_k127_4096428_3	583355.Caka_3010	1.027e-97	326.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,3K7EN@414999|Opitutae	414999|Opitutae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS1_k127_4096428_6	227086.JGI_V11_88467	3.746e-52	194.0	COG0790@1|root,KOG1550@2759|Eukaryota	227086.JGI_V11_88467|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4096428_4	243231.GSU2601	7.535e-96	342.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,43TUT@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
CMS1_k127_4096428_8	83406.HDN1F_27740	1.24e-37	159.0	COG0463@1|root,COG0463@2|Bacteria,1RBHD@1224|Proteobacteria,1S3K4@1236|Gammaproteobacteria,1J96N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_4096428_11	316067.Geob_0646	2.217e-31	127.0	COG5442@1|root,COG5442@2|Bacteria,1REZ8@1224|Proteobacteria,42W1U@68525|delta/epsilon subdivisions,2WRE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar protein FlaF	-	-	-	ko:K06602	-	-	-	-	ko00000,ko02035	-	-	-	FlaF
CMS1_k127_4096428_10	316067.Geob_0645	1.493e-34	136.0	COG5443@1|root,COG5443@2|Bacteria,1RD3V@1224|Proteobacteria,42UAH@68525|delta/epsilon subdivisions,2WQUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellar FlbT family protein	flbT	-	-	ko:K06601	-	-	-	-	ko00000,ko02035	-	-	-	FlbT
CMS1_k127_4096428_12	398767.Glov_3370	2.439e-27	127.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
CMS1_k127_4127088_0	1286170.RORB6_23420	8.274e-161	551.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS1_k127_4127088_1	194439.CT1068	9.535e-52	199.0	COG1330@1|root,COG1330@2|Bacteria,1FEMY@1090|Chlorobi	1090|Chlorobi	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
CMS1_k127_4131866_0	867845.KI911784_gene2774	0.0007383	52.0	COG1413@1|root,COG1674@1|root,COG5635@1|root,COG1413@2|Bacteria,COG1674@2|Bacteria,COG5635@2|Bacteria,2G8R0@200795|Chloroflexi,3766B@32061|Chloroflexia	32061|Chloroflexia	CDT	Armadillo/beta-catenin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS1_k127_4146743_3	330214.NIDE3335	4.126e-28	114.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01421,ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
CMS1_k127_4146743_1	330214.NIDE3338	6.34e-114	377.0	COG1131@1|root,COG1131@2|Bacteria,3J116@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4146743_0	330214.NIDE3339	1.068e-124	402.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569,ko:K03532,ko:K15876	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko02000	5.A.3.4	-	-	Cytochrom_NNT,Cytochrome_C7
CMS1_k127_4146743_2	330214.NIDE3340	2.914e-80	270.0	COG1763@1|root,COG1763@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.10.1.1,2.7.7.77	ko:K03750,ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R09735,R11581	RC03462	ko00000,ko00001,ko01000	-	-	iB21_1397.B21_03691,iBWG_1329.BWG_3527,iECBD_1354.ECBD_4174,iECDH1ME8569_1439.ECDH1ME8569_3728,iEcDH1_1363.EcDH1_4130,iJO1366.b3856,iSbBS512_1146.SbBS512_E4328,iY75_1357.Y75_RS17805	MoCF_biosynth,MobB,MoeA_C,MoeA_N
CMS1_k127_4152945_0	228410.NE1277	6.625e-181	594.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,2VK1A@28216|Betaproteobacteria,371Y7@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4152945_1	583355.Caka_1313	5.942e-30	130.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_4193944_2	158822.LH89_05475	3.596e-45	181.0	2EA0S@1|root,33465@2|Bacteria,1N7SI@1224|Proteobacteria,1SC7Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4193944_3	1340493.JNIF01000003_gene1364	3.27e-06	59.0	COG3137@1|root,COG3137@2|Bacteria,3Y380@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS1_k127_4193944_0	1123070.KB899259_gene2014	6.495e-156	497.0	COG0451@1|root,COG0451@2|Bacteria,46TPV@74201|Verrucomicrobia,2IWKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_4193944_1	472759.Nhal_3583	6.536e-55	199.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1WY3R@135613|Chromatiales	135613|Chromatiales	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS1_k127_4196274_2	398767.Glov_3597	9.429e-105	372.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS1_k127_4196274_1	583355.Caka_1752	1.559e-112	373.0	COG0809@1|root,COG0809@2|Bacteria,46SDA@74201|Verrucomicrobia,3K7T6@414999|Opitutae	414999|Opitutae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS1_k127_4196274_0	1122236.KB905143_gene52	7.569e-121	398.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2VHDA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	cation diffusion facilitator family transporter	czcD2	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
CMS1_k127_4196274_3	1144275.COCOR_04513	9.695e-73	256.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S4J@68525|delta/epsilon subdivisions,2WNH4@28221|Deltaproteobacteria,2YTUZ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_4196274_4	382464.ABSI01000013_gene1628	2e-22	100.0	COG0571@1|root,COG0571@2|Bacteria,46WCW@74201|Verrucomicrobia,2IUR4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ribonuclease III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196274_5	382464.ABSI01000010_gene3290	1.3e-13	77.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,2ITPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS1_k127_4200174_3	583355.Caka_0907	1.389e-05	54.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,zf-IS66
CMS1_k127_4200174_0	583355.Caka_0906	1.522e-68	254.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4200174_1	583355.Caka_2162	8.364e-49	181.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia,3K843@414999|Opitutae	414999|Opitutae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_4200174_2	794903.OPIT5_05610	2.129e-11	67.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia,3K8DC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4203663_1	702113.PP1Y_AT22100	6.323e-71	268.0	COG2865@1|root,COG2865@2|Bacteria,1R4MD@1224|Proteobacteria,2UNC2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
CMS1_k127_4203663_0	1198114.AciX9_3108	3.037e-84	299.0	COG1431@1|root,COG1431@2|Bacteria,3Y550@57723|Acidobacteria,2JJPC@204432|Acidobacteriia	204432|Acidobacteriia	J	PFAM Stem cell self-renewal protein Piwi	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4227278_4	382464.ABSI01000002_gene4281	2.898e-105	346.0	COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,2ITKK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_4227278_6	452637.Oter_2745	2.584e-85	288.0	COG0106@1|root,COG0106@2|Bacteria,46SVR@74201|Verrucomicrobia,3K79Z@414999|Opitutae	414999|Opitutae	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_4227278_3	1403819.BATR01000128_gene4550	1.502e-114	385.0	COG1538@1|root,COG1538@2|Bacteria,46SFR@74201|Verrucomicrobia,2IUDN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_4227278_1	1122604.JONR01000015_gene111	6.166e-135	439.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,1X52V@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_4227278_2	1502851.FG93_00554	2.117e-119	398.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2TU59@28211|Alphaproteobacteria,3JTPV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	ABC-2 family transporter protein	MA20_09460	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_4227278_0	1449065.JMLL01000010_gene164	3.588e-222	703.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2TW58@28211|Alphaproteobacteria,43IE8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	GV	Multidrug ABC transporter ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_tran
CMS1_k127_4227278_5	595537.Varpa_1912	9.962e-92	312.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2VH7G@28216|Betaproteobacteria,4AFAF@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993,ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_4227278_7	706587.Desti_3800	1.981e-31	130.0	COG1309@1|root,COG1309@2|Bacteria,1NAQF@1224|Proteobacteria,42S96@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_4231459_1	382464.ABSI01000021_gene399	1.882e-32	129.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
CMS1_k127_4231459_0	583355.Caka_2841	0.0	1393.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,46SAT@74201|Verrucomicrobia,3K7FK@414999|Opitutae	414999|Opitutae	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_4243748_0	1047013.AQSP01000100_gene593	1.201e-77	273.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4243748_3	867845.KI911784_gene2277	0.0004736	42.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS1_k127_4243748_2	446462.Amir_6221	9.26e-07	60.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E2B1@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_4243748_1	761193.Runsl_1946	1.81e-16	81.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4307839_1	1232410.KI421417_gene2727	6.196e-106	359.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2X2B8@28221|Deltaproteobacteria,43U8G@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
CMS1_k127_4307839_7	865861.AZSU01000004_gene965	0.0001071	44.0	2BBRW@1|root,325A1@2|Bacteria,1URDA@1239|Firmicutes,24WPQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4307839_4	382464.ABSI01000021_gene423	2.744e-58	206.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,2IU7V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
CMS1_k127_4307839_0	583355.Caka_1137	1.683e-153	492.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	414999|Opitutae	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_4307839_3	278957.ABEA03000203_gene2721	3.98e-72	254.0	COG0181@1|root,COG0181@2|Bacteria,46SWD@74201|Verrucomicrobia,3K7RT@414999|Opitutae	414999|Opitutae	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	-	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS1_k127_4307839_2	382464.ABSI01000021_gene425	4.313e-76	263.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia,2ITRR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CMS1_k127_4307839_5	382464.ABSI01000021_gene427	1.658e-47	179.0	COG0135@1|root,COG0135@2|Bacteria,46VS4@74201|Verrucomicrobia,2IUJV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS1_k127_4307839_6	452637.Oter_3091	3.386e-12	74.0	2960M@1|root,2ZTB9@2|Bacteria,46WKQ@74201|Verrucomicrobia,3K8I3@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4307839_8	1279038.KB907344_gene3579	0.0001761	52.0	COG4380@1|root,COG4380@2|Bacteria,1R3WM@1224|Proteobacteria,2U71Q@28211|Alphaproteobacteria,2JXJ5@204441|Rhodospirillales	204441|Rhodospirillales	S	Putative bacterial lipoprotein (DUF799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF799
CMS1_k127_4352268_0	583355.Caka_2452	9.281e-174	557.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia,3K7HY@414999|Opitutae	414999|Opitutae	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C
CMS1_k127_4352268_1	278957.ABEA03000174_gene3411	3.515e-24	107.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_4357170_0	1379281.AVAG01000009_gene610	2.01e-199	629.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2M8EP@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4357170_2	278957.ABEA03000095_gene4577	7.687e-16	85.0	COG1030@1|root,COG1030@2|Bacteria,46TB9@74201|Verrucomicrobia,3K87X@414999|Opitutae	414999|Opitutae	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS1_k127_4357170_1	794903.OPIT5_17140	3.099e-38	147.0	COG2890@1|root,COG2890@2|Bacteria,46SZE@74201|Verrucomicrobia,3K75Z@414999|Opitutae	414999|Opitutae	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	Methyltransf_31
CMS1_k127_4377239_1	1144313.PMI10_01710	7.668e-197	626.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia,2NSMA@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
CMS1_k127_4377239_2	264732.Moth_2025	2.825e-178	571.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,42EP0@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_4377239_0	1123070.KB899257_gene2302	5.166e-199	628.0	COG2115@1|root,COG2115@2|Bacteria,46TT2@74201|Verrucomicrobia,2ITJ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4377239_3	583355.Caka_2985	4.857e-94	322.0	COG0823@1|root,COG0823@2|Bacteria,46SSK@74201|Verrucomicrobia,3K7CU@414999|Opitutae	414999|Opitutae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_4377239_4	583355.Caka_1216	3.898e-53	192.0	COG2151@1|root,COG2151@2|Bacteria,46VI1@74201|Verrucomicrobia,3K7B6@414999|Opitutae	414999|Opitutae	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS1_k127_4377239_6	794903.OPIT5_09815	2.631e-29	121.0	COG3536@1|root,COG3536@2|Bacteria,46VNP@74201|Verrucomicrobia,3K8AJ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS1_k127_4377239_7	935866.JAER01000053_gene2967	1.661e-12	74.0	COG0454@1|root,COG0456@2|Bacteria,2I1AK@201174|Actinobacteria,4DSWJ@85009|Propionibacteriales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4377239_5	1297742.A176_06371	4.267e-32	136.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_4381963_2	382464.ABSI01000005_gene1108	1.861e-18	89.0	COG0508@1|root,COG0508@2|Bacteria,46SD3@74201|Verrucomicrobia,2ITTQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl
CMS1_k127_4381963_0	583355.Caka_2169	1.016e-166	541.0	COG2203@1|root,COG3605@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,3K7H5@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS1_k127_4381963_1	583355.Caka_2170	1.395e-96	326.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia,3K7SE@414999|Opitutae	414999|Opitutae	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
CMS1_k127_4424412_2	309807.SRU_0415	1.483e-53	203.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,1FJZ3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS1_k127_4424412_1	452637.Oter_1527	5.143e-74	256.0	COG3279@1|root,COG3279@2|Bacteria,46X3T@74201|Verrucomicrobia,3K9Q8@414999|Opitutae	414999|Opitutae	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS1_k127_4424412_0	583355.Caka_1857	3.902e-96	319.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,3K77W@414999|Opitutae	414999|Opitutae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_443467_0	935567.JAES01000053_gene1747	2.501e-318	991.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X5F3@135614|Xanthomonadales	135614|Xanthomonadales	P	Outer membrane receptor proteins mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_443467_5	452637.Oter_1388	1.566e-61	218.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
CMS1_k127_443467_1	452637.Oter_1389	2.109e-233	745.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_443467_2	935567.JAES01000016_gene1483	2.246e-203	642.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1X4DT@135614|Xanthomonadales	135614|Xanthomonadales	G	Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS1_k127_443467_3	452637.Oter_1392	1.004e-148	476.0	COG3940@1|root,COG3940@2|Bacteria,46U5F@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS1_k127_443467_4	1121957.ATVL01000007_gene2078	5.928e-117	391.0	COG3507@1|root,COG3507@2|Bacteria,4NFU3@976|Bacteroidetes,47NII@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43,RicinB_lectin_2
CMS1_k127_4461567_0	452637.Oter_2052	4.559e-225	708.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,3K7JR@414999|Opitutae	414999|Opitutae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_4461567_6	1396141.BATP01000028_gene2376	1.054e-112	377.0	COG1118@1|root,COG1118@2|Bacteria,46S68@74201|Verrucomicrobia,2IV37@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_4461567_5	452637.Oter_2064	9.964e-113	371.0	COG4208@1|root,COG4208@2|Bacteria,46SIX@74201|Verrucomicrobia,3K7HZ@414999|Opitutae	414999|Opitutae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
CMS1_k127_4461567_4	748247.AZKH_3257	8.915e-113	372.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KV4D@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
CMS1_k127_4461567_3	1122929.KB908235_gene2283	1.804e-134	437.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2TT52@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
CMS1_k127_4461567_7	743721.Psesu_2270	7.39e-62	231.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS1_k127_4461567_8	497964.CfE428DRAFT_0276	5.762e-56	200.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_4461567_2	340099.Teth39_1665	4.036e-161	520.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,42FEB@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM Ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
CMS1_k127_4461567_9	382464.ABSI01000021_gene421	2.448e-53	189.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia,2IUGB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Nitrogen regulatory protein P-II	-	-	-	-	-	-	-	-	-	-	-	-	P-II
CMS1_k127_4461567_1	583355.Caka_0746	3.37e-164	523.0	COG0082@1|root,COG0082@2|Bacteria,46SEA@74201|Verrucomicrobia,3K7DA@414999|Opitutae	414999|Opitutae	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS1_k127_4461567_14	1408422.JHYF01000043_gene3830	4.406e-10	60.0	2BEY2@1|root,328PR@2|Bacteria,1UUMT@1239|Firmicutes,2576E@186801|Clostridia,36TJM@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4461567_13	1541065.JRFE01000052_gene4176	1.937e-12	69.0	2EK6X@1|root,33DXA@2|Bacteria,1GFHH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4461567_10	566461.SSFG_05974	3.27e-19	88.0	2DMHR@1|root,32RMI@2|Bacteria,2HC0U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4461567_11	402777.KB235903_gene430	1.785e-17	85.0	2AFZF@1|root,3163A@2|Bacteria,1GG27@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4461567_17	568703.LGG_00821	0.0006911	42.0	292C0@1|root,2ZPWE@2|Bacteria,1W1IU@1239|Firmicutes,4I189@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4468479_1	439235.Dalk_3930	1.144e-76	279.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2MIG6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_4468479_0	794903.OPIT5_01475	1.253e-172	550.0	COG4284@1|root,COG4284@2|Bacteria,46U9U@74201|Verrucomicrobia,3K7T1@414999|Opitutae	414999|Opitutae	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.23,2.7.7.64,2.7.7.83	ko:K00972,ko:K12447	ko00040,ko00052,ko00053,ko00520,ko01100,ko01130,map00040,map00052,map00053,map00520,map01100,map01130	M00014,M00361,M00362	R00289,R00416,R00502,R01381,R03077,R08845	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS1_k127_4520222_5	1249627.D779_0241	9.009e-52	186.0	COG4615@1|root,COG4615@2|Bacteria,1MVIC@1224|Proteobacteria,1RMYK@1236|Gammaproteobacteria,1WWNW@135613|Chromatiales	135613|Chromatiales	PQ	pfam abc	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_4520222_6	1249627.D779_3685	2.286e-41	158.0	COG3597@1|root,COG3597@2|Bacteria,1MZA4@1224|Proteobacteria,1S95Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	DUF697
CMS1_k127_4520222_12	1249627.D779_3686	4.149e-09	59.0	2DU5T@1|root,33P1T@2|Bacteria,1NGSS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4520222_9	452637.Oter_1761	1.339e-30	130.0	COG0799@1|root,COG0799@2|Bacteria,46WCF@74201|Verrucomicrobia,3K89X@414999|Opitutae	414999|Opitutae	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS1_k127_4520222_7	382464.ABSI01000011_gene2745	4.545e-34	139.0	COG1057@1|root,COG1057@2|Bacteria,46YSF@74201|Verrucomicrobia,2IUSZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_4520222_1	1121440.AUMA01000020_gene1959	2.094e-96	326.0	COG1092@1|root,COG1092@2|Bacteria,1Q08C@1224|Proteobacteria,42RRW@68525|delta/epsilon subdivisions,2WNY5@28221|Deltaproteobacteria,2MAYH@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_4520222_8	794903.OPIT5_29490	1.098e-32	134.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4520222_10	1479237.JMLY01000001_gene759	1.202e-29	121.0	COG2929@1|root,COG2929@2|Bacteria,1MZZZ@1224|Proteobacteria,1S69H@1236|Gammaproteobacteria,46BB2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_4520222_11	1041146.ATZB01000036_gene688	5.979e-17	84.0	COG5304@1|root,COG5304@2|Bacteria,1N269@1224|Proteobacteria,2UD6T@28211|Alphaproteobacteria,4BG44@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
CMS1_k127_4520222_0	382464.ABSI01000005_gene1278	8.758e-133	440.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_4520222_3	583355.Caka_2102	3.179e-87	306.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS1_k127_4520222_2	583355.Caka_2101	9.26e-91	303.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,3K7XM@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4520222_4	583355.Caka_2100	3.265e-62	219.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,3K7JB@414999|Opitutae	414999|Opitutae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_4540030_0	382464.ABSI01000017_gene67	7.973e-134	435.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CMS1_k127_4540030_2	1121904.ARBP01000006_gene3857	7.056e-31	130.0	COG0847@1|root,COG0847@2|Bacteria,4NMUI@976|Bacteroidetes,47PI2@768503|Cytophagia	976|Bacteroidetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS1_k127_4540030_1	290512.Paes_1034	1.134e-31	130.0	COG2905@1|root,COG2905@2|Bacteria,1FDR9@1090|Chlorobi	1090|Chlorobi	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS1_k127_4541847_10	278957.ABEA03000203_gene2702	3.774e-13	72.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia,3K7P8@414999|Opitutae	414999|Opitutae	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS1_k127_4541847_4	794903.OPIT5_06540	1.513e-84	286.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,3K7DM@414999|Opitutae	414999|Opitutae	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS1_k127_4541847_0	583355.Caka_0913	5.722e-132	431.0	COG0820@1|root,COG0820@2|Bacteria,46UPK@74201|Verrucomicrobia,3K7AA@414999|Opitutae	414999|Opitutae	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_4541847_5	583355.Caka_1884	4.416e-79	275.0	COG0324@1|root,COG0324@2|Bacteria,46T1C@74201|Verrucomicrobia,3K7IR@414999|Opitutae	414999|Opitutae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_4541847_2	396588.Tgr7_2734	5.837e-113	377.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,1WW8E@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_4541847_9	583355.Caka_1637	3.984e-17	89.0	2FF2I@1|root,3470U@2|Bacteria,46W1E@74201|Verrucomicrobia,3K8ET@414999|Opitutae	414999|Opitutae	S	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_4541847_8	583355.Caka_1638	1.373e-20	103.0	COG4795@1|root,COG4795@2|Bacteria,46WEK@74201|Verrucomicrobia,3K851@414999|Opitutae	414999|Opitutae	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_4541847_6	794903.OPIT5_25390	2.468e-28	128.0	COG3156@1|root,COG3156@2|Bacteria,46WC4@74201|Verrucomicrobia,3K829@414999|Opitutae	414999|Opitutae	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS1_k127_4541847_7	583355.Caka_1640	1.178e-21	108.0	COG4972@1|root,COG4972@2|Bacteria,46WVK@74201|Verrucomicrobia,3K8A8@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4541847_11	794903.OPIT5_25400	3.973e-11	73.0	2BMCF@1|root,32FWN@2|Bacteria,46XUN@74201|Verrucomicrobia,3K8A6@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM_b
CMS1_k127_4541847_3	583355.Caka_1642	2.833e-107	376.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS1_k127_4541847_1	243090.RB3482	1.253e-126	424.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_4541847_14	565045.NOR51B_2657	0.0006429	45.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1J8NV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG1459 Type II secretory pathway, component PulF	xpsF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_4547432_3	1396141.BATP01000060_gene4729	1.182e-27	126.0	29ZR2@1|root,30MRV@2|Bacteria,46XMI@74201|Verrucomicrobia,2IW71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4547432_0	583355.Caka_2607	5.634e-177	565.0	COG0498@1|root,COG0498@2|Bacteria,46TPG@74201|Verrucomicrobia,3K7E5@414999|Opitutae	414999|Opitutae	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CMS1_k127_4547432_1	583355.Caka_2605	5.988e-172	548.0	COG0527@1|root,COG0527@2|Bacteria,46TWW@74201|Verrucomicrobia,3K7MP@414999|Opitutae	414999|Opitutae	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_4547432_2	574087.Acear_1069	6.982e-126	416.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WA7N@53433|Halanaerobiales	186801|Clostridia	E	PFAM Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS1_k127_4547432_4	435591.BDI_3667	8.456e-23	101.0	COG0778@1|root,COG0778@2|Bacteria,4NP0K@976|Bacteroidetes,2FPFS@200643|Bacteroidia,22XYX@171551|Porphyromonadaceae	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_4585941_7	1189612.A33Q_3873	8.636e-07	54.0	COG3884@1|root,COG3884@2|Bacteria,4NMMY@976|Bacteroidetes,47PHB@768503|Cytophagia	976|Bacteroidetes	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
CMS1_k127_4585941_1	644282.Deba_3048	7.61e-67	233.0	2AQX7@1|root,31G5S@2|Bacteria,1RGXB@1224|Proteobacteria,430QC@68525|delta/epsilon subdivisions,2WW2G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4585941_0	382464.ABSI01000010_gene3657	3.011e-99	331.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CMS1_k127_4585941_5	756499.Desde_2677	1.179e-31	130.0	COG0346@1|root,COG0346@2|Bacteria,1V6CB@1239|Firmicutes,25BFW@186801|Clostridia,265DN@186807|Peptococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
CMS1_k127_4585941_2	452637.Oter_0402	1.248e-55	203.0	COG1191@1|root,COG1191@2|Bacteria,46TPW@74201|Verrucomicrobia,3K7F7@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_4585941_4	382464.ABSI01000005_gene1130	5.305e-45	171.0	COG1595@1|root,COG1595@2|Bacteria,46VAA@74201|Verrucomicrobia,2IUMN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4585941_3	1123257.AUFV01000005_gene1304	9.009e-46	170.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,1S2G0@1236|Gammaproteobacteria,1X6YM@135614|Xanthomonadales	135614|Xanthomonadales	S	acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
CMS1_k127_4585941_6	118005.AWNK01000002_gene1741	2.845e-23	102.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CMS1_k127_4587895_0	765911.Thivi_0558	2.084e-160	510.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_4587895_1	583355.Caka_1959	4.311e-58	205.0	COG1225@1|root,COG1225@2|Bacteria,46V63@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_4587895_2	382464.ABSI01000011_gene2595	8.793e-47	186.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
CMS1_k127_458923_0	349521.HCH_05001	2.051e-137	458.0	COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XI12@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M
CMS1_k127_458923_2	243365.CV_2062	2.559e-18	87.0	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,2KU4B@206351|Neisseriales	206351|Neisseriales	CO	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
CMS1_k127_458923_1	1168067.JAGP01000001_gene465	1.945e-18	94.0	COG1434@1|root,COG1434@2|Bacteria,1N8RS@1224|Proteobacteria,1SDWN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS1_k127_458923_3	314292.VAS14_15299	0.0007563	48.0	2E65Y@1|root,330UM@2|Bacteria,1N8U3@1224|Proteobacteria,1SCHF@1236|Gammaproteobacteria,1Y278@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4593149_1	452637.Oter_2208	4.992e-46	177.0	COG4625@1|root,COG4625@2|Bacteria,46UI9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Rhamnogalacturonan lyase B, N-terminal	-	-	4.2.2.23	ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
CMS1_k127_4593149_3	926550.CLDAP_02060	6.751e-11	76.0	COG1807@1|root,COG1807@2|Bacteria,2G8SF@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4593149_2	1469613.JT55_13225	5.865e-29	125.0	COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,2TWRY@28211|Alphaproteobacteria,3FEGK@34008|Rhodovulum	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	ykcC	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS1_k127_4593149_0	240016.ABIZ01000001_gene3062	2.257e-144	468.0	COG0058@1|root,COG0058@2|Bacteria,46S5T@74201|Verrucomicrobia,2IV91@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase
CMS1_k127_4626043_1	1379698.RBG1_1C00001G0055	1.157e-29	131.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
CMS1_k127_4626043_0	880073.Calab_3744	1.472e-61	228.0	COG4219@1|root,COG4219@2|Bacteria,2NR11@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
CMS1_k127_4626060_1	118168.MC7420_487	1.764e-07	57.0	2DGIJ@1|root,2ZW4N@2|Bacteria,1GH3J@1117|Cyanobacteria,1HH1C@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4626060_0	1499967.BAYZ01000016_gene6498	1.19e-09	60.0	2E3CI@1|root,32YBU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CMS1_k127_4628566_4	452637.Oter_4317	5.9e-35	138.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS1_k127_4628566_1	583355.Caka_1070	1.556e-95	320.0	COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia,3K7NP@414999|Opitutae	414999|Opitutae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
CMS1_k127_4628566_2	452637.Oter_2577	1.69e-91	307.0	COG1043@1|root,COG1043@2|Bacteria,46SD4@74201|Verrucomicrobia,3K7A9@414999|Opitutae	414999|Opitutae	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS1_k127_4628566_0	452637.Oter_2576	1.957e-172	552.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,3K7GH@414999|Opitutae	414999|Opitutae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CMS1_k127_4628566_3	1122604.JONR01000029_gene3382	1.287e-45	172.0	COG1309@1|root,COG1309@2|Bacteria,1PZUN@1224|Proteobacteria,1RY6D@1236|Gammaproteobacteria,1X6AD@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_4628566_5	243233.MCA2814	1.143e-22	104.0	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,1XEPS@135618|Methylococcales	135618|Methylococcales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_4652099_7	292414.TM1040_1196	3.943e-07	54.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,2TT6H@28211|Alphaproteobacteria,4NAVX@97050|Ruegeria	28211|Alphaproteobacteria	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
CMS1_k127_4652099_2	439497.RR11_3064	1.146e-59	214.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2TUCA@28211|Alphaproteobacteria,4NBVE@97050|Ruegeria	28211|Alphaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase family protein	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_4652099_1	1288298.rosmuc_01092	6.628e-75	254.0	COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria,46QPA@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
CMS1_k127_4652099_4	83219.PM02_13055	6.233e-47	184.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,2U2YW@28211|Alphaproteobacteria,3ZWWU@60136|Sulfitobacter	28211|Alphaproteobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS1_k127_4652099_8	862751.SACTE_3149	0.0004132	43.0	COG0702@1|root,COG0702@2|Bacteria,2GKXI@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_4652099_5	1280944.HY17_03075	2.002e-42	160.0	COG1846@1|root,COG1846@2|Bacteria,1QASF@1224|Proteobacteria,2TTQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	MarR family	MA20_19890	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_4652099_6	1280944.HY17_03070	5.219e-19	91.0	COG2259@1|root,COG2259@2|Bacteria,1N06A@1224|Proteobacteria,2U6MK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM DoxX family protein	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_4652099_0	1461694.ATO9_20500	1.422e-82	281.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2TS1B@28211|Alphaproteobacteria,2PFH3@252301|Oceanicola	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gstch1	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CMS1_k127_4652099_3	1002340.AFCF01000062_gene690	6.147e-48	173.0	COG2329@1|root,COG2329@2|Bacteria,1N1IT@1224|Proteobacteria,2UCHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_4663087_2	583355.Caka_0908	1.558e-28	118.0	COG0696@1|root,COG0696@2|Bacteria,46U4C@74201|Verrucomicrobia,3K7DS@414999|Opitutae	414999|Opitutae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS1_k127_4663087_0	382464.ABSI01000007_gene4073	9.191e-71	254.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	GO:0000272,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010391,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0017144,GO:0042737,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0045491,GO:0045493,GO:0046555,GO:0052689,GO:0071554,GO:0071704,GO:1901575,GO:2000884	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_4663087_1	382464.ABSI01000007_gene4073	2.014e-68	246.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	GO:0000272,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010391,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0017144,GO:0042737,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0045491,GO:0045493,GO:0046555,GO:0052689,GO:0071554,GO:0071704,GO:1901575,GO:2000884	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_4665822_0	382464.ABSI01000011_gene2821	6.566e-51	184.0	COG4608@1|root,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,2ITPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_4665822_1	583355.Caka_2288	1.326e-28	132.0	COG1262@1|root,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	414999|Opitutae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_4676134_5	530564.Psta_1401	0.0004308	46.0	COG2017@1|root,COG2017@2|Bacteria,2IWRW@203682|Planctomycetes	203682|Planctomycetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS1_k127_4676134_2	880073.Calab_0031	4.023e-105	349.0	COG2017@1|root,COG2017@2|Bacteria,2NQA5@2323|unclassified Bacteria	2|Bacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS1_k127_4676134_0	452637.Oter_2443	5.327e-182	587.0	COG1080@1|root,COG1080@2|Bacteria,46TX4@74201|Verrucomicrobia,3K7JG@414999|Opitutae	414999|Opitutae	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS1_k127_4676134_3	794903.OPIT5_14920	1.487e-48	185.0	COG1947@1|root,COG1947@2|Bacteria,46SV6@74201|Verrucomicrobia,3K807@414999|Opitutae	414999|Opitutae	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_4676134_1	583355.Caka_1202	5.493e-119	394.0	COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,3K7MM@414999|Opitutae	414999|Opitutae	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_4676134_4	452637.Oter_0095	2.232e-22	109.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia,3K7T2@414999|Opitutae	414999|Opitutae	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4680747_5	452637.Oter_2336	6.428e-84	291.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia,3K7IB@414999|Opitutae	414999|Opitutae	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
CMS1_k127_4680747_2	382464.ABSI01000023_gene542	4.392e-130	423.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,2ITT3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_4680747_4	583355.Caka_1316	2e-118	398.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	414999|Opitutae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_4680747_6	1120973.AQXL01000133_gene1837	1.516e-44	168.0	COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,4ISFT@91061|Bacilli	91061|Bacilli	J	rRNA methylase	ytqB	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
CMS1_k127_4680747_0	497964.CfE428DRAFT_1607	0.0	1169.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_4680747_7	278957.ABEA03000061_gene3160	5.721e-38	148.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,3K84E@414999|Opitutae	414999|Opitutae	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4680747_3	452637.Oter_2687	5.362e-126	419.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,46SWK@74201|Verrucomicrobia,3K87J@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,PAS_3,SpoIIE
CMS1_k127_4680747_1	382464.ABSI01000005_gene1170	4.783e-165	533.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia,2ITJ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	4-alpha-glucanotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_77
CMS1_k127_4701015_2	794903.OPIT5_20620	1.736e-19	94.0	2CGCF@1|root,33ZA6@2|Bacteria,46YV0@74201|Verrucomicrobia,3K85C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4701015_1	452637.Oter_3753	9.379e-49	183.0	COG0564@1|root,COG0564@2|Bacteria,46VI2@74201|Verrucomicrobia,3K84H@414999|Opitutae	414999|Opitutae	J	Pseudouridine synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
CMS1_k127_4701015_0	382464.ABSI01000013_gene1834	8.596e-118	391.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,46TR8@74201|Verrucomicrobia,2IU7X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Peripla_BP_3
CMS1_k127_4719537_1	452637.Oter_2989	2.016e-116	382.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia,3K7Q7@414999|Opitutae	414999|Opitutae	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_4719537_2	583355.Caka_0848	3.142e-77	270.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,3K7AR@414999|Opitutae	414999|Opitutae	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
CMS1_k127_4719537_3	794903.OPIT5_28795	2.574e-32	128.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,3K8AZ@414999|Opitutae	414999|Opitutae	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS1_k127_4719537_0	716541.ECL_03729	2.392e-145	467.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,1RMIG@1236|Gammaproteobacteria,3X0QI@547|Enterobacter	1236|Gammaproteobacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_4719537_4	1237149.C900_05552	4.147e-08	65.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,47TYM@768503|Cytophagia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
CMS1_k127_4733271_3	452637.Oter_0475	3.073e-98	332.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,3K73G@414999|Opitutae	414999|Opitutae	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS1_k127_4733271_0	794903.OPIT5_14125	7.001e-161	522.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,3K7GC@414999|Opitutae	414999|Opitutae	C	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS1_k127_4733271_2	583355.Caka_2581	1.1e-135	448.0	COG1007@1|root,COG1007@2|Bacteria,46UXV@74201|Verrucomicrobia,3K7C5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS1_k127_4733271_5	794903.OPIT5_25080	2.17e-34	139.0	COG1406@1|root,COG1406@2|Bacteria,46VWI@74201|Verrucomicrobia,3K86V@414999|Opitutae	414999|Opitutae	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
CMS1_k127_4733271_1	452637.Oter_0435	7.127e-155	497.0	COG0745@1|root,COG0745@2|Bacteria,46V0J@74201|Verrucomicrobia,3K7HQ@414999|Opitutae	414999|Opitutae	T	PFAM response regulator receiver	-	-	2.7.7.65	ko:K02488,ko:K02658,ko:K03413	ko02020,ko02025,ko02030,ko04112,map02020,map02025,map02030,map04112	M00506,M00507,M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02044	-	-	-	Response_reg
CMS1_k127_4733271_4	382464.ABSI01000016_gene715	9.686e-45	171.0	COG1191@1|root,COG1191@2|Bacteria,46TPW@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_4749602_0	1121335.Clst_1220	1.068e-14	83.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3WI9J@541000|Ruminococcaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_4749602_1	493475.GARC_1621	8.94e-07	63.0	COG1664@1|root,COG1664@2|Bacteria,1QUZJ@1224|Proteobacteria,1T318@1236|Gammaproteobacteria,46D2K@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Concanavalin A-like lectin/glucanases superfamily	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,H_lectin,Laminin_G_3,PA14
CMS1_k127_4753803_3	452637.Oter_0413	2.418e-23	104.0	COG1580@1|root,COG1580@2|Bacteria,46W5Y@74201|Verrucomicrobia,3K86H@414999|Opitutae	414999|Opitutae	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
CMS1_k127_4753803_0	382464.ABSI01000016_gene705	9.156e-122	400.0	COG1868@1|root,COG1868@2|Bacteria	2|Bacteria	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	-	-	ko:K02416,ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliM,FliMN_C
CMS1_k127_4753803_2	452637.Oter_0411	3.092e-34	134.0	COG1886@1|root,COG1886@2|Bacteria,46W1T@74201|Verrucomicrobia,3K8A2@414999|Opitutae	414999|Opitutae	N	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
CMS1_k127_4753803_4	1036674.A28LD_0474	6.991e-08	61.0	COG3190@1|root,COG3190@2|Bacteria,1PQ34@1224|Proteobacteria,1SX48@1236|Gammaproteobacteria,2QGK2@267893|Idiomarinaceae	1236|Gammaproteobacteria	N	Flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
CMS1_k127_4753803_1	382464.ABSI01000016_gene708	3.549e-77	267.0	COG1338@1|root,COG1338@2|Bacteria,46USW@74201|Verrucomicrobia	74201|Verrucomicrobia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
CMS1_k127_477326_0	574376.BAMA_21695	7.611e-06	55.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_4783717_26	583355.Caka_1635	1.125e-18	86.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilW-2	-	-	ko:K02456,ko:K02650,ko:K02672	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,T2SSG
CMS1_k127_4783717_28	1282361.ABAC402_02940	7.018e-06	51.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2KH8R@204458|Caulobacterales	204458|Caulobacterales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS1_k127_4783717_1	452637.Oter_2780	4.729e-248	780.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,3K7CY@414999|Opitutae	414999|Opitutae	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS1_k127_4783717_25	278957.ABEA03000152_gene4082	1.713e-19	92.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,3K871@414999|Opitutae	414999|Opitutae	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CMS1_k127_4783717_20	583355.Caka_2122	1.2e-35	139.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,3K8AH@414999|Opitutae	414999|Opitutae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
CMS1_k127_4783717_12	452637.Oter_3495	6.719e-51	192.0	COG0705@1|root,COG0705@2|Bacteria,46T9P@74201|Verrucomicrobia,3K802@414999|Opitutae	414999|Opitutae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_4783717_7	278957.ABEA03000071_gene3035	9.946e-64	222.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,3K7YQ@414999|Opitutae	414999|Opitutae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS1_k127_4783717_5	583355.Caka_1708	7.374e-69	236.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,3K7QA@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS1_k127_4783717_0	452637.Oter_0228	0.0	1029.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	414999|Opitutae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_4783717_13	452637.Oter_0227	9.888e-51	183.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia,3K86C@414999|Opitutae	414999|Opitutae	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS1_k127_4783717_4	583355.Caka_1690	3.135e-71	247.0	COG0087@1|root,COG0087@2|Bacteria,46U5V@74201|Verrucomicrobia,3K7BQ@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS1_k127_4783717_8	583355.Caka_1689	9.976e-59	211.0	COG0088@1|root,COG0088@2|Bacteria,46SWJ@74201|Verrucomicrobia,3K7CA@414999|Opitutae	414999|Opitutae	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS1_k127_4783717_29	262723.MS53_0641	0.0008302	46.0	COG0089@1|root,COG0089@2|Bacteria,3WTSC@544448|Tenericutes	544448|Tenericutes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS1_k127_4783717_2	583355.Caka_1687	1.207e-102	341.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,3K7DN@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS1_k127_4783717_22	382464.ABSI01000011_gene2666	5.643e-32	126.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,2IUPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS1_k127_4783717_21	583355.Caka_1684	6.669e-33	130.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia,3K89B@414999|Opitutae	414999|Opitutae	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS1_k127_4783717_3	278957.ABEA03000071_gene3046	6.773e-91	303.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS1_k127_4783717_11	452637.Oter_0219	1.718e-55	197.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia,3K7Z4@414999|Opitutae	414999|Opitutae	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS1_k127_4783717_27	398578.Daci_0399	1.229e-06	52.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,4AFHC@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS1_k127_4783717_23	583355.Caka_1680	7.615e-31	124.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,3K88E@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS1_k127_4783717_16	382464.ABSI01000011_gene2660	1.113e-45	168.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,2IUB7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS1_k127_4783717_24	382464.ABSI01000011_gene2659	7.515e-20	91.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS1_k127_4783717_10	583355.Caka_1677	2.778e-57	205.0	COG0094@1|root,COG0094@2|Bacteria,46SP7@74201|Verrucomicrobia,3K7AF@414999|Opitutae	414999|Opitutae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS1_k127_4783717_18	583355.Caka_1676	4.445e-43	160.0	COG0199@1|root,COG0199@2|Bacteria,46X64@74201|Verrucomicrobia,3K84A@414999|Opitutae	414999|Opitutae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS1_k127_4783717_15	583355.Caka_1675	7.428e-46	169.0	COG0096@1|root,COG0096@2|Bacteria,46T2K@74201|Verrucomicrobia,3K839@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS1_k127_4783717_9	583355.Caka_1674	7.629e-58	206.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,3K7WU@414999|Opitutae	414999|Opitutae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS1_k127_4783717_17	382464.ABSI01000011_gene2654	1.214e-43	162.0	COG0256@1|root,COG0256@2|Bacteria,46T7Z@74201|Verrucomicrobia,2IUJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS1_k127_4783717_6	382464.ABSI01000011_gene2653	6.884e-66	233.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia,2IUC7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS1_k127_4783717_19	794903.OPIT5_02335	1.178e-40	156.0	COG0200@1|root,COG0200@2|Bacteria,46VGD@74201|Verrucomicrobia,3K832@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS1_k127_4783717_14	382464.ABSI01000011_gene2651	1.494e-47	172.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,2ITRX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_4814156_2	760192.Halhy_1062	1.195e-86	294.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1IPGB@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_4814156_4	203122.Sde_2868	6.555e-48	190.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria,1SAFU@1236|Gammaproteobacteria,46DJS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
CMS1_k127_4814156_0	583355.Caka_1121	2.912e-188	593.0	COG0524@1|root,COG0524@2|Bacteria,46TGU@74201|Verrucomicrobia,3K7M0@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS1_k127_4814156_3	583355.Caka_1122	4.034e-64	227.0	COG0800@1|root,COG0800@2|Bacteria,46V8F@74201|Verrucomicrobia,3K9JW@414999|Opitutae	414999|Opitutae	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
CMS1_k127_4814156_1	1340493.JNIF01000003_gene4524	6.757e-91	304.0	COG1904@1|root,COG1904@2|Bacteria,3Y2S9@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
CMS1_k127_4834182_13	983548.Krodi_1332	0.0008731	44.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1HWY3@117743|Flavobacteriia,37EG9@326319|Dokdonia	976|Bacteroidetes	S	Protein of unknown function (DUF1194)	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CMS1_k127_4834182_11	1035839.AFNK01000085_gene486	0.0002964	44.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4834182_9	944480.ATUV01000002_gene384	1.3e-25	118.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WKQH@28221|Deltaproteobacteria,2M6KM@213113|Desulfurellales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_4834182_4	452637.Oter_0686	1.779e-76	265.0	COG1127@1|root,COG1127@2|Bacteria,46SRC@74201|Verrucomicrobia,3K7XJ@414999|Opitutae	414999|Opitutae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_4834182_5	452637.Oter_0685	7.919e-75	259.0	COG0767@1|root,COG0767@2|Bacteria,46ZIM@74201|Verrucomicrobia,3K7D7@414999|Opitutae	414999|Opitutae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS1_k127_4834182_3	452637.Oter_0684	2.324e-90	315.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
CMS1_k127_4834182_7	382464.ABSI01000012_gene2135	9.208e-41	157.0	COG0742@1|root,COG0742@2|Bacteria,46T62@74201|Verrucomicrobia,2IUEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
CMS1_k127_4834182_1	382464.ABSI01000005_gene1007	9.862e-180	574.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia,2ITMX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS1_k127_4834182_0	278957.ABEA03000044_gene4153	0.0	1040.0	COG1328@1|root,COG1328@2|Bacteria,46TE5@74201|Verrucomicrobia,3K8FY@414999|Opitutae	414999|Opitutae	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
CMS1_k127_4834182_12	1121019.AUMN01000024_gene3561	0.0008692	46.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_4834182_8	583355.Caka_3005	1.144e-26	111.0	COG0228@1|root,COG0228@2|Bacteria,46WC2@74201|Verrucomicrobia,3K8CM@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS1_k127_4834182_2	382464.ABSI01000002_gene4279	1.731e-90	303.0	COG0336@1|root,COG0336@2|Bacteria,46SS0@74201|Verrucomicrobia,2ITZV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA (Guanine-1)-methyltransferase	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS1_k127_4834182_6	583355.Caka_3007	2.871e-47	172.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia,3K87M@414999|Opitutae	414999|Opitutae	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS1_k127_4869869_0	583355.Caka_2692	4.645e-286	887.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,3K77R@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS1_k127_4869869_5	756272.Plabr_0073	2.334e-82	286.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS1_k127_4869869_3	497964.CfE428DRAFT_6003	6.788e-98	333.0	COG1408@1|root,COG1408@2|Bacteria,46T0Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS1_k127_4869869_6	452637.Oter_0874	1.056e-28	119.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,3K83V@414999|Opitutae	414999|Opitutae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CMS1_k127_4869869_1	1173021.ALWA01000012_gene1268	3.196e-207	653.0	COG0055@1|root,COG0055@2|Bacteria,1G1BK@1117|Cyanobacteria	1117|Cyanobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_4869869_4	583355.Caka_2110	2.807e-83	286.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia,3K742@414999|Opitutae	414999|Opitutae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS1_k127_4869869_2	382464.ABSI01000012_gene2278	3.155e-151	484.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia,2ITR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS1_k127_4874653_4	1410620.SHLA_52c000200	8.55e-13	72.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TT3X@28211|Alphaproteobacteria,4BAZC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_4874653_2	583355.Caka_2360	3.65e-84	287.0	COG0131@1|root,COG0131@2|Bacteria,46UDT@74201|Verrucomicrobia,3K7V8@414999|Opitutae	414999|Opitutae	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS1_k127_4874653_3	583355.Caka_1597	4.981e-74	265.0	COG0668@1|root,COG0668@2|Bacteria,46UFI@74201|Verrucomicrobia,3K8BZ@414999|Opitutae	414999|Opitutae	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS1_k127_4874653_1	583355.Caka_2361	1.605e-84	284.0	COG0118@1|root,COG0118@2|Bacteria,46V4G@74201|Verrucomicrobia,3K758@414999|Opitutae	414999|Opitutae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_4874653_0	583355.Caka_2362	2.445e-189	601.0	COG0372@1|root,COG0372@2|Bacteria,46SBV@74201|Verrucomicrobia,3K7TE@414999|Opitutae	414999|Opitutae	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_4882400_8	644282.Deba_2479	3.125e-57	228.0	COG2984@1|root,COG4120@1|root,COG2984@2|Bacteria,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,42P9P@68525|delta/epsilon subdivisions,2WJPI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01989,ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind,BPD_transp_2
CMS1_k127_4882400_9	794903.OPIT5_07140	7.428e-47	194.0	COG2984@1|root,COG2984@2|Bacteria,46YPH@74201|Verrucomicrobia,3K9XT@414999|Opitutae	414999|Opitutae	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS1_k127_4882400_5	794903.OPIT5_07145	8.277e-63	231.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
CMS1_k127_4882400_3	794903.OPIT5_07150	1.14e-99	334.0	COG4120@1|root,COG4120@2|Bacteria,46YK2@74201|Verrucomicrobia,3K9RK@414999|Opitutae	414999|Opitutae	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
CMS1_k127_4882400_2	794903.OPIT5_07155	1.061e-101	339.0	COG1101@1|root,COG1101@2|Bacteria,46YSY@74201|Verrucomicrobia,3K9UK@414999|Opitutae	414999|Opitutae	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
CMS1_k127_4882400_0	497964.CfE428DRAFT_6595	3.987e-240	762.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_4882400_6	1121935.AQXX01000089_gene4699	2.349e-61	222.0	COG3209@1|root,COG3209@2|Bacteria,1RJSQ@1224|Proteobacteria,1S7V3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4882400_1	382464.ABSI01000011_gene3071	1.639e-170	548.0	COG0008@1|root,COG0008@2|Bacteria,46SJ3@74201|Verrucomicrobia,2ITYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_4882400_4	1121451.DESAM_22184	4.539e-97	335.0	COG2172@1|root,COG2172@2|Bacteria,1RAZR@1224|Proteobacteria,42QXY@68525|delta/epsilon subdivisions,2WN4X@28221|Deltaproteobacteria,2MCFT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,HATPase_c_2
CMS1_k127_4882400_7	7159.AAEL017480-PA	1.319e-59	218.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria,41TJ6@6656|Arthropoda,3SIDI@50557|Insecta,458BN@7147|Diptera	33208|Metazoa	M	Ankyrin repeat	-	-	-	ko:K05643	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.211	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
CMS1_k127_4891048_3	1000565.METUNv1_01001	5.642e-23	101.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2VKKB@28216|Betaproteobacteria,2KX5M@206389|Rhodocyclales	206389|Rhodocyclales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N_3
CMS1_k127_4891048_0	215803.DB30_1760	7.292e-93	313.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,42SXE@68525|delta/epsilon subdivisions,2WUXE@28221|Deltaproteobacteria,2YUTE@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
CMS1_k127_4891048_1	266265.Bxe_A1399	9.834e-51	184.0	COG0346@1|root,COG0346@2|Bacteria,1RI06@1224|Proteobacteria,2VTBG@28216|Betaproteobacteria,1K7SQ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS1_k127_4891048_2	388051.AUFE01000086_gene2249	1.89e-38	149.0	COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,2VICI@28216|Betaproteobacteria,1K0YQ@119060|Burkholderiaceae	28216|Betaproteobacteria	KQ	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
CMS1_k127_4903755_0	1123237.Salmuc_01626	3.016e-60	211.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2U3FU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_4910708_2	450851.PHZ_c1730	2.074e-41	156.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2KF8K@204458|Caulobacterales	204458|Caulobacterales	T	nitrogen regulation protein NR(I)	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_4910708_0	1282876.BAOK01000001_gene2154	1.863e-211	681.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,4BPAV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	ntrY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_4910708_1	414684.RC1_0131	2.691e-121	395.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,2JQX5@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_4926681_1	935567.JAES01000006_gene407	1.862e-92	313.0	COG1988@1|root,COG1988@2|Bacteria,1QK5N@1224|Proteobacteria,1S0MU@1236|Gammaproteobacteria,1X507@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
CMS1_k127_4926681_0	1121448.DGI_2998	4.869e-104	348.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
CMS1_k127_4926681_3	382464.ABSI01000010_gene3845	1.551e-49	196.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
CMS1_k127_4926681_2	583355.Caka_1553	5.567e-91	305.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,3K7FJ@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS1_k127_493985_3	382464.ABSI01000013_gene1860	1.563e-91	312.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia,2IWNG@203494|Verrucomicrobiae	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_493985_2	382464.ABSI01000013_gene1861	1.148e-99	339.0	COG0845@1|root,COG0845@2|Bacteria,46UK7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_493985_4	1267535.KB906767_gene628	1.235e-78	279.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria,2JHXU@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_493985_0	926566.Terro_2393	1.051e-130	432.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_493985_1	452637.Oter_3898	5.727e-127	422.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia,3K9Y4@414999|Opitutae	414999|Opitutae	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS1_k127_494381_3	1565129.JSFF01000003_gene2066	3.315e-09	61.0	28JGK@1|root,2Z9AA@2|Bacteria,1MWFY@1224|Proteobacteria,1RPK6@1236|Gammaproteobacteria,2QA4W@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3034)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3034
CMS1_k127_494381_0	1229172.JQFA01000005_gene141	3.467e-136	454.0	COG1165@1|root,COG1165@2|Bacteria,1G1FW@1117|Cyanobacteria,1H8TT@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
CMS1_k127_494381_2	756272.Plabr_4031	5.307e-41	169.0	COG1680@1|root,COG1680@2|Bacteria,2IZDA@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_494381_1	583355.Caka_1109	4.046e-51	187.0	COG0524@1|root,COG0524@2|Bacteria,46W0T@74201|Verrucomicrobia,3K79H@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_4946942_3	479431.Namu_3763	3.075e-18	87.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4ETG1@85013|Frankiales	201174|Actinobacteria	GK	PFAM ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_4946942_1	1192034.CAP_1548	6.316e-49	184.0	COG0491@1|root,COG0491@2|Bacteria,1RJ82@1224|Proteobacteria,430SI@68525|delta/epsilon subdivisions,2WW32@28221|Deltaproteobacteria,2YV7P@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_4946942_0	1121904.ARBP01000009_gene4184	2.349e-54	200.0	2CH0A@1|root,2ZANK@2|Bacteria,4P0FB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4946942_2	113395.AXAI01000003_gene5869	3.255e-40	156.0	COG3644@1|root,COG3644@2|Bacteria,1RK12@1224|Proteobacteria,2U9IH@28211|Alphaproteobacteria,3JU7P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2239)	-	-	-	ko:K09965	-	-	-	-	ko00000	-	-	-	DUF2239
CMS1_k127_4949138_4	452637.Oter_3553	1.234e-57	207.0	COG1694@1|root,COG3956@2|Bacteria,46V21@74201|Verrucomicrobia,3K767@414999|Opitutae	414999|Opitutae	S	Nucleotide pyrophosphohydrolase	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
CMS1_k127_4949138_2	583355.Caka_1743	6.384e-91	314.0	COG0134@1|root,COG0134@2|Bacteria,46TR6@74201|Verrucomicrobia,3K7YE@414999|Opitutae	414999|Opitutae	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS1_k127_4949138_5	589865.DaAHT2_1320	6.686e-28	118.0	COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,42X8X@68525|delta/epsilon subdivisions,2WR9M@28221|Deltaproteobacteria,2MQ04@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
CMS1_k127_4949138_1	452637.Oter_3555	8.607e-93	312.0	COG0030@1|root,COG0030@2|Bacteria,46UMH@74201|Verrucomicrobia,3K7MA@414999|Opitutae	414999|Opitutae	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_4949138_0	479434.Sthe_1093	1.849e-226	720.0	COG0366@1|root,COG0366@2|Bacteria,2G89J@200795|Chloroflexi,27XYW@189775|Thermomicrobia	189775|Thermomicrobia	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
CMS1_k127_4949138_3	1121448.DGI_0528	4.223e-83	284.0	COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,42NK2@68525|delta/epsilon subdivisions,2WM0C@28221|Deltaproteobacteria,2MA6J@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
CMS1_k127_4950948_9	794903.OPIT5_16235	2.311e-25	110.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,3K7FW@414999|Opitutae	414999|Opitutae	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_4950948_0	247490.KSU1_C0661	1.64e-188	606.0	COG0488@1|root,COG0488@2|Bacteria,2IX59@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_4950948_8	278957.ABEA03000149_gene4062	3.918e-31	130.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,3K8IG@414999|Opitutae	414999|Opitutae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CMS1_k127_4950948_7	404380.Gbem_1762	8.279e-33	139.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
CMS1_k127_4950948_2	240015.ACP_0421	2.428e-98	335.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria,2JI77@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_4950948_1	657309.BXY_31750	4.523e-146	485.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,2G05U@200643|Bacteroidia,4AWF6@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
CMS1_k127_4950948_3	1403819.BATR01000112_gene3710	1.476e-88	303.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,2IV3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
CMS1_k127_4950948_5	511.JT27_01295	3.753e-69	243.0	COG1708@1|root,COG1708@2|Bacteria,1R03C@1224|Proteobacteria,2WB33@28216|Betaproteobacteria,3T40C@506|Alcaligenaceae	28216|Betaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4950948_4	794903.OPIT5_10930	1.448e-70	250.0	COG0715@1|root,COG0715@2|Bacteria,46X2C@74201|Verrucomicrobia,3K9J8@414999|Opitutae	414999|Opitutae	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_4950948_6	317619.ANKN01000109_gene1374	2.906e-63	223.0	COG0778@1|root,COG0778@2|Bacteria,1G4SQ@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_4950948_10	316274.Haur_4550	0.0004335	46.0	COG4552@1|root,COG4552@2|Bacteria,2GAIZ@200795|Chloroflexi,376FX@32061|Chloroflexia	32061|Chloroflexia	S	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS1_k127_49836_0	90814.KL370892_gene2309	5.522e-43	169.0	COG1864@1|root,COG1864@2|Bacteria,1RADP@1224|Proteobacteria,1S30S@1236|Gammaproteobacteria,46156@72273|Thiotrichales	72273|Thiotrichales	F	DNA RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
CMS1_k127_49836_1	1163617.SCD_n02777	1.654e-24	105.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS1_k127_5000931_0	452637.Oter_2710	3.278e-57	214.0	COG0438@1|root,COG0438@2|Bacteria,46U8D@74201|Verrucomicrobia,3K8XI@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5000931_2	794903.OPIT5_16175	6.586e-05	55.0	COG1538@1|root,COG1538@2|Bacteria,46WAX@74201|Verrucomicrobia,3K8JE@414999|Opitutae	414999|Opitutae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_5000931_1	452637.Oter_3939	1.954e-44	175.0	COG0845@1|root,COG0845@2|Bacteria,46TGD@74201|Verrucomicrobia,3K82M@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_5002066_5	1282360.ABAC460_00245	6.929e-28	116.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31,PA14
CMS1_k127_5002066_1	452637.Oter_3286	1.727e-152	495.0	COG1233@1|root,COG1233@2|Bacteria,46TRV@74201|Verrucomicrobia,3K78Y@414999|Opitutae	414999|Opitutae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS1_k127_5002066_4	452637.Oter_3287	6.402e-36	142.0	COG0236@1|root,COG0236@2|Bacteria,46W39@74201|Verrucomicrobia,3K88G@414999|Opitutae	414999|Opitutae	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS1_k127_5002066_0	583355.Caka_1850	1.383e-200	631.0	COG0304@1|root,COG0304@2|Bacteria,46V0S@74201|Verrucomicrobia,3K7MU@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_5002066_3	1380391.JIAS01000003_gene1899	2.844e-65	235.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,2TWSB@28211|Alphaproteobacteria,2JUB1@204441|Rhodospirillales	204441|Rhodospirillales	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS1_k127_5002066_2	1406840.Q763_11550	2.36e-147	476.0	COG3664@1|root,COG3664@2|Bacteria,4NHQ0@976|Bacteroidetes,1I5WJ@117743|Flavobacteriia,2NTYP@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
CMS1_k127_5037527_1	452637.Oter_2334	3.331e-144	475.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,3K73M@414999|Opitutae	414999|Opitutae	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS1_k127_5037527_2	583355.Caka_1584	8.203e-133	439.0	COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,3K7R2@414999|Opitutae	414999|Opitutae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS1_k127_5037527_5	452637.Oter_2332	3.886e-49	180.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,3K82A@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS1_k127_5037527_0	382464.ABSI01000011_gene3075	5.712e-174	562.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5037527_6	1048983.EL17_06200	3.321e-31	134.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,47RCS@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_5037527_4	583355.Caka_2753	1.156e-62	224.0	COG4821@1|root,COG4821@2|Bacteria,46UCV@74201|Verrucomicrobia,3K7J3@414999|Opitutae	414999|Opitutae	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
CMS1_k127_5037527_3	583355.Caka_2446	9.58e-72	248.0	COG2131@1|root,COG2131@2|Bacteria,46WJA@74201|Verrucomicrobia,3K7XK@414999|Opitutae	414999|Opitutae	F	dCMP deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
CMS1_k127_5046488_3	1043493.BBLU01000005_gene2053	4.207e-11	72.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	-	-	-	-	-	-	-	-	-	RyR,TrkA_N
CMS1_k127_5046488_0	1469607.KK073768_gene4469	3.098e-70	270.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G15Q@1117|Cyanobacteria,1HMTX@1161|Nostocales	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10
CMS1_k127_5046488_2	240016.ABIZ01000001_gene1991	2.302e-22	114.0	COG0457@1|root,COG0457@2|Bacteria,46SWY@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12
CMS1_k127_5046488_1	522306.CAP2UW1_2075	3.303e-53	215.0	COG0457@1|root,COG3012@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3012@2|Bacteria,COG3903@2|Bacteria,1MWRF@1224|Proteobacteria,2VVW1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7
CMS1_k127_5046488_4	278957.ABEA03000120_gene1217	2.425e-06	55.0	2C6KN@1|root,33CID@2|Bacteria	2|Bacteria	S	VRR-NUC domain	-	-	-	-	-	-	-	-	-	-	-	-	VRR_NUC
CMS1_k127_5049203_1	382464.ABSI01000010_gene3353	1.241e-111	393.0	COG1629@1|root,COG1629@2|Bacteria	382464.ABSI01000010_gene3353|-	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5049203_0	452637.Oter_3219	1.63e-252	807.0	COG1472@1|root,COG1472@2|Bacteria,46YSG@74201|Verrucomicrobia,3K7RC@414999|Opitutae	414999|Opitutae	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_5052837_0	391616.OA238_c47390	2.127e-159	502.0	COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,2TTKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide	amiE	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_5052837_1	391613.RTM1035_01380	3.453e-146	471.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,46NCT@74030|Roseovarius	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_5063765_3	927704.SELR_02330	8.812e-28	119.0	COG0845@1|root,COG0845@2|Bacteria,1U1UF@1239|Firmicutes,4H27Y@909932|Negativicutes	909932|Negativicutes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18302	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_5063765_0	1122604.JONR01000029_gene3380	9.408e-305	965.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X41A@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18303	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.17	-	-	ACR_tran
CMS1_k127_5063765_2	1392838.AWNM01000070_gene1240	2.032e-52	205.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VKED@28216|Betaproteobacteria,3T6UW@506|Alcaligenaceae	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_5063765_1	583355.Caka_1393	1.405e-98	330.0	COG0685@1|root,COG0685@2|Bacteria,46U74@74201|Verrucomicrobia,3K7A3@414999|Opitutae	414999|Opitutae	C	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_5095525_3	794903.OPIT5_03800	7.417e-103	349.0	COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,46YQB@74201|Verrucomicrobia,3K9ZV@414999|Opitutae	414999|Opitutae	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5095525_6	794903.OPIT5_03805	3.78e-40	156.0	COG4385@1|root,COG4385@2|Bacteria	2|Bacteria	T	Tail protein	I	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
CMS1_k127_5095525_4	1492922.GY26_12315	1.148e-75	263.0	COG3948@1|root,COG3948@2|Bacteria,1MUFF@1224|Proteobacteria,1RNBJ@1236|Gammaproteobacteria,1J98T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Baseplate J-like protein	J	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CMS1_k127_5095525_8	225937.HP15_664	3.927e-27	115.0	COG3628@1|root,COG3628@2|Bacteria,1N7WS@1224|Proteobacteria,1SCD1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Baseplate assembly protein	gpW	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
CMS1_k127_5095525_7	1121451.DESAM_10239	5.349e-34	139.0	COG4540@1|root,COG4540@2|Bacteria,1N2WK@1224|Proteobacteria,42WW6@68525|delta/epsilon subdivisions,2WTD5@28221|Deltaproteobacteria,2MDP5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	phage baseplate assembly protein V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_base_V
CMS1_k127_5095525_9	1399147.P618_200460	3.512e-23	106.0	2DNH4@1|root,32XGS@2|Bacteria,1N1FJ@1224|Proteobacteria,2VFWD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5095525_12	794903.OPIT5_29350	3.051e-05	52.0	2BFH8@1|root,329AZ@2|Bacteria,46YH7@74201|Verrucomicrobia,3K9K9@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5095525_11	1121448.DGI_0220	1.224e-06	55.0	COG5566@1|root,COG5566@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mor
CMS1_k127_5095525_2	452637.Oter_0526	9.675e-165	539.0	COG0457@1|root,COG2755@1|root,COG0457@2|Bacteria,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N,Lipase_GDSL_2,SLH,TPR_16,TPR_19,fn3
CMS1_k127_5095525_0	452637.Oter_0524	4.349e-244	767.0	COG2192@1|root,COG2192@2|Bacteria,46UIP@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Carbamoyltransferase N-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS1_k127_5095525_1	452637.Oter_0522	1.471e-181	597.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_5095525_5	382464.ABSI01000010_gene3227	1.913e-58	214.0	COG1609@1|root,COG1609@2|Bacteria,46TVE@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PFAM regulatory protein LacI	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI
CMS1_k127_5105207_0	298654.FraEuI1c_5462	5.064e-79	271.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5105207_1	1280954.HPO_13922	1.955e-71	250.0	COG1028@1|root,COG1028@2|Bacteria,1NU26@1224|Proteobacteria,2UPB1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5105207_2	383381.EH30_10795	1.092e-33	133.0	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,2UC83@28211|Alphaproteobacteria,2K5XY@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_5105679_0	382464.ABSI01000011_gene2642	1.772e-97	328.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	2|Bacteria	E	Aminotransferase class I and II	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.hisC	Aminotran_1_2
CMS1_k127_5105679_9	1089550.ATTH01000001_gene2286	4.07e-41	159.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1FJBZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
CMS1_k127_5105679_6	452637.Oter_0682	2.64e-52	194.0	COG1385@1|root,COG1385@2|Bacteria,46V87@74201|Verrucomicrobia,3K833@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_5105679_5	794903.OPIT5_25160	1.926e-57	210.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia,3K7WK@414999|Opitutae	414999|Opitutae	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS1_k127_5105679_2	583355.Caka_3002	6.138e-78	268.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,3K77K@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_5105679_3	909663.KI867150_gene2768	4.259e-72	267.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43BN0@68525|delta/epsilon subdivisions,2X702@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
CMS1_k127_5105679_4	765912.Thimo_1260	3.456e-60	220.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria,1WWNT@135613|Chromatiales	135613|Chromatiales	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
CMS1_k127_5105679_8	1121405.dsmv_0359	7.3e-45	174.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WNBB@28221|Deltaproteobacteria,2MK5J@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS1_k127_5105679_1	452637.Oter_4515	2.043e-96	329.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Cellulase,NHL,RicinB_lectin_2
CMS1_k127_5105679_7	382464.ABSI01000013_gene1699	5.431e-50	182.0	COG0835@1|root,COG0835@2|Bacteria,46VRE@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS1_k127_5118532_2	497964.CfE428DRAFT_0077	6.202e-54	208.0	COG1538@1|root,COG1538@2|Bacteria,46T1E@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_5118532_0	583355.Caka_1787	1.622e-154	505.0	COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,3K7PG@414999|Opitutae	414999|Opitutae	IQ	AMP-dependent synthetase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
CMS1_k127_5118532_4	583355.Caka_1951	4.036e-31	130.0	COG1266@1|root,COG1266@2|Bacteria,46XTZ@74201|Verrucomicrobia,3K831@414999|Opitutae	414999|Opitutae	S	Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_5118532_1	452637.Oter_2373	4.227e-94	321.0	COG0006@1|root,COG0006@2|Bacteria,46SKG@74201|Verrucomicrobia,3K72M@414999|Opitutae	414999|Opitutae	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_5118532_3	266117.Rxyl_1172	1.009e-41	157.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria	201174|Actinobacteria	GK	polyphosphate glucokinase	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_5124060_0	794903.OPIT5_05350	1.131e-56	199.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,3K79T@414999|Opitutae	414999|Opitutae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_5125911_4	82654.Pse7367_3237	7.525e-06	49.0	COG0500@1|root,COG2226@2|Bacteria,1G3RV@1117|Cyanobacteria,1H8Z1@1150|Oscillatoriales	1117|Cyanobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5125911_1	1235797.C816_01668	7.357e-70	249.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,24BZ3@186801|Clostridia	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_5125911_2	349521.HCH_00727	5.847e-44	175.0	292MS@1|root,2ZQ5N@2|Bacteria,1N3H9@1224|Proteobacteria,1SGA5@1236|Gammaproteobacteria,1XQTS@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5125911_0	452637.Oter_3226	7.579e-224	701.0	COG2272@1|root,COG2272@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS1_k127_5125913_2	227086.JGI_V11_87924	1.261e-11	65.0	COG0423@1|root,KOG2298@2759|Eukaryota	2759|Eukaryota	J	glycyl-tRNA aminoacylation	-	-	-	-	-	-	-	-	-	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS1_k127_5125913_1	1291050.JAGE01000002_gene3761	8.019e-124	416.0	COG4193@1|root,COG5297@1|root,COG4193@2|Bacteria,COG5297@2|Bacteria,1TQYK@1239|Firmicutes,25F9V@186801|Clostridia,3WHN1@541000|Ruminococcaceae	186801|Clostridia	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Dockerin_1,Glyco_hydro_9
CMS1_k127_5125913_3	583355.Caka_2276	2.815e-05	56.0	2F1FE@1|root,33UG5@2|Bacteria,46V5X@74201|Verrucomicrobia,3K8V2@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5125913_0	583355.Caka_1596	3.011e-219	693.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia,3K7IC@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_5134752_15	1408473.JHXO01000012_gene442	3.991e-10	60.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,2FQ6R@200643|Bacteroidia	976|Bacteroidetes	S	esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS1_k127_5134752_4	452637.Oter_3628	6.971e-151	488.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CMS1_k127_5134752_10	794903.OPIT5_21140	5.93e-62	218.0	COG1853@1|root,COG1853@2|Bacteria,46YS6@74201|Verrucomicrobia,3K927@414999|Opitutae	414999|Opitutae	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_5134752_16	794903.OPIT5_18230	7.407e-09	57.0	COG0230@1|root,COG0230@2|Bacteria,46XWC@74201|Verrucomicrobia,3K8GI@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_5134752_14	583355.Caka_2473	7.421e-14	76.0	COG0594@1|root,COG0594@2|Bacteria,46WMC@74201|Verrucomicrobia,3K8HX@414999|Opitutae	414999|Opitutae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS1_k127_5134752_13	349741.Amuc_1255	5.558e-25	106.0	COG0759@1|root,COG0759@2|Bacteria,46W3D@74201|Verrucomicrobia,2IW7G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Haemolytic	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS1_k127_5134752_6	583355.Caka_2475	9.713e-133	444.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,3K72P@414999|Opitutae	414999|Opitutae	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS1_k127_5134752_8	583355.Caka_0864	8.218e-73	254.0	COG1043@1|root,COG1043@2|Bacteria,46V8M@74201|Verrucomicrobia,3K837@414999|Opitutae	414999|Opitutae	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS1_k127_5134752_7	794903.OPIT5_27975	1.05e-110	366.0	COG1995@1|root,COG1995@2|Bacteria,46SNQ@74201|Verrucomicrobia,3K7JT@414999|Opitutae	414999|Opitutae	C	Belongs to the PdxA family	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS1_k127_5134752_5	278957.ABEA03000094_gene4806	1.88e-140	453.0	COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,3K7TX@414999|Opitutae	414999|Opitutae	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS1_k127_5134752_17	794903.OPIT5_08100	0.0003696	50.0	2A1H5@1|root,30PQU@2|Bacteria,46XXG@74201|Verrucomicrobia,3K8JI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5134752_0	517418.Ctha_2166	0.0	1990.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1FDQP@1090|Chlorobi	1090|Chlorobi	C	glutamate synthase, alpha subunit domain protein	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_5134752_2	870187.Thini_4188	3.364e-213	673.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,45ZPY@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS1_k127_5134752_3	583355.Caka_1603	2.237e-152	490.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,3K7BN@414999|Opitutae	414999|Opitutae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS1_k127_5134752_9	583355.Caka_2222	3.768e-71	248.0	COG2738@1|root,COG2738@2|Bacteria,46THF@74201|Verrucomicrobia,3K7WD@414999|Opitutae	414999|Opitutae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS1_k127_5134752_12	583355.Caka_2842	2.239e-27	120.0	COG0369@1|root,COG0369@2|Bacteria,46VHX@74201|Verrucomicrobia,3K93B@414999|Opitutae	414999|Opitutae	P	Flavodoxin	-	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_1
CMS1_k127_5134752_11	338966.Ppro_3332	1.504e-50	193.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
CMS1_k127_5134752_1	452637.Oter_3868	1.248e-308	958.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia,3K736@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_5137337_0	583355.Caka_1741	5.597e-256	799.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia,3K79W@414999|Opitutae	414999|Opitutae	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS1_k127_5137337_1	1003200.AXXA_23460	6.896e-121	413.0	COG0457@1|root,COG0457@2|Bacteria,1RBMC@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5137337_2	449447.MAE_45070	2.279e-20	104.0	COG5542@1|root,COG5542@2|Bacteria,1G3SR@1117|Cyanobacteria	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
CMS1_k127_5148074_3	391619.PGA1_c18240	0.0008902	49.0	COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1RKKJ@1224|Proteobacteria	1224|Proteobacteria	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
CMS1_k127_5148074_2	1122201.AUAZ01000004_gene3406	1.856e-09	61.0	2EFU7@1|root,339KB@2|Bacteria,1NH5H@1224|Proteobacteria,1SGNP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage tail assembly chaperone proteins, E, or 41 or 14	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_7
CMS1_k127_5148074_1	1500897.JQNA01000001_gene5799	5.149e-39	151.0	COG3498@1|root,COG3498@2|Bacteria,1Q8HB@1224|Proteobacteria,2WFNQ@28216|Betaproteobacteria,1K7JZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phage tail tube protein FII	-	-	-	ko:K06908	-	-	-	-	ko00000	-	-	-	Phage_tube
CMS1_k127_5148074_0	225937.HP15_654	1.439e-127	427.0	COG3497@1|root,COG3497@2|Bacteria,1MW1V@1224|Proteobacteria,1RNUT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
CMS1_k127_5194095_0	1396141.BATP01000007_gene5689	1.648e-204	654.0	COG4146@1|root,COG4146@2|Bacteria,46UV3@74201|Verrucomicrobia,2ITNB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_5194095_2	583355.Caka_1185	8.098e-61	223.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,3K7JD@414999|Opitutae	414999|Opitutae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
CMS1_k127_5194095_1	278957.ABEA03000157_gene652	1.506e-176	580.0	COG1199@1|root,COG1199@2|Bacteria,46TTB@74201|Verrucomicrobia,3K7UT@414999|Opitutae	414999|Opitutae	KL	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	DEAD_2,Helicase_C_2
CMS1_k127_5196848_1	911045.PSE_p0173	4.077e-90	305.0	COG0662@1|root,COG4977@1|root,COG0662@2|Bacteria,COG4977@2|Bacteria,1R8XV@1224|Proteobacteria,2U2RN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
CMS1_k127_5196848_0	911045.PSE_p0174	4.912e-125	402.0	COG1335@1|root,COG1335@2|Bacteria,1N48X@1224|Proteobacteria,2U17G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG1335 Amidases related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_5202808_4	313624.NSP_50100	1.325e-17	93.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
CMS1_k127_5202808_2	330214.NIDE2391	3.155e-46	178.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5202808_5	1122986.KB908319_gene96	2.961e-13	82.0	COG2244@1|root,COG2244@2|Bacteria,4NT7E@976|Bacteroidetes,2FXBN@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_5202808_1	583355.Caka_1979	8.241e-76	284.0	COG3525@1|root,COG3525@2|Bacteria,46WQ6@74201|Verrucomicrobia,3KA1V@414999|Opitutae	414999|Opitutae	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
CMS1_k127_5202808_0	1158338.JNLJ01000001_gene1201	2.766e-113	368.0	COG0451@1|root,COG0451@2|Bacteria,2G3NS@200783|Aquificae	200783|Aquificae	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
CMS1_k127_5226249_1	278957.ABEA03000121_gene3933	4.981e-155	497.0	COG1034@1|root,COG1034@2|Bacteria,46S6S@74201|Verrucomicrobia,3K7F9@414999|Opitutae	414999|Opitutae	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3
CMS1_k127_5226249_0	485918.Cpin_1810	9.732e-239	769.0	COG3250@1|root,COG3250@2|Bacteria,4PHX1@976|Bacteroidetes,1IRK0@117747|Sphingobacteriia	976|Bacteroidetes	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_5226249_2	935567.JAES01000033_gene865	1.172e-82	290.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1X3QZ@135614|Xanthomonadales	135614|Xanthomonadales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,AAA_30,UvrD_C_2,Viral_helicase1
CMS1_k127_523647_0	382464.ABSI01000002_gene4257	5.067e-152	491.0	COG0326@1|root,COG0326@2|Bacteria,46U76@74201|Verrucomicrobia,2IU3I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
CMS1_k127_523647_1	583355.Caka_1567	3.276e-150	481.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,3K7DX@414999|Opitutae	414999|Opitutae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_5292424_10	202956.BBNL01000002_gene1212	2.192e-05	53.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,3NSXG@468|Moraxellaceae	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
CMS1_k127_5292424_1	316067.Geob_3224	3.382e-52	204.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,42V8Q@68525|delta/epsilon subdivisions,2WRSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_5292424_8	876044.IMCC3088_892	6.126e-15	85.0	COG1462@1|root,COG1462@2|Bacteria,1RH5B@1224|Proteobacteria,1SAKG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
CMS1_k127_5292424_4	452637.Oter_3905	1.012e-26	117.0	COG0848@1|root,COG0848@2|Bacteria,46WER@74201|Verrucomicrobia,3K80N@414999|Opitutae	414999|Opitutae	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_5292424_3	583355.Caka_1361	3.038e-46	177.0	COG0811@1|root,COG0811@2|Bacteria,46VC6@74201|Verrucomicrobia,3K7Z8@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_5292424_0	583355.Caka_2811	2.474e-74	254.0	COG0066@1|root,COG0066@2|Bacteria,46U20@74201|Verrucomicrobia,3K7RN@414999|Opitutae	414999|Opitutae	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_5292424_7	452637.Oter_0926	6.643e-21	98.0	COG0071@1|root,COG0071@2|Bacteria,46T3G@74201|Verrucomicrobia,3K860@414999|Opitutae	414999|Opitutae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_5292424_6	1403819.BATR01000094_gene2977	1.319e-21	98.0	COG0071@1|root,COG0071@2|Bacteria,46WVG@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS1_k127_5292424_9	1443113.LC20_00103	1.517e-06	61.0	2AKJ2@1|root,31BB2@2|Bacteria,1QGAG@1224|Proteobacteria,1TDPR@1236|Gammaproteobacteria,41H3E@629|Yersinia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5292424_2	1123072.AUDH01000015_gene2151	2.475e-48	196.0	2DM0M@1|root,3175D@2|Bacteria,1MYGG@1224|Proteobacteria,2UA4C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5292424_5	316058.RPB_3231	1.163e-23	115.0	2DM0M@1|root,3175D@2|Bacteria,1MYGG@1224|Proteobacteria,2UA4C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5295650_1	1123355.JHYO01000013_gene1109	7.824e-20	95.0	2DGYK@1|root,32U89@2|Bacteria,1N2VG@1224|Proteobacteria,2UDEE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5313759_0	768670.Calni_2017	1.05e-133	432.0	COG1350@1|root,COG1350@2|Bacteria,2GEX9@200930|Deferribacteres	200930|Deferribacteres	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_5313759_1	760568.Desku_0812	1.112e-66	236.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,262AM@186807|Peptococcaceae	186801|Clostridia	I	PFAM Enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS1_k127_5313759_2	439235.Dalk_0731	2.704e-34	134.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,42NEJ@68525|delta/epsilon subdivisions,2WM86@28221|Deltaproteobacteria,2MJ18@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS1_k127_5314703_0	382464.ABSI01000005_gene1401	6.942e-108	372.0	COG0189@1|root,COG0586@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,46UXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	HJ	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_5314703_1	329726.AM1_0053	1.07e-11	72.0	2CHH4@1|root,32SC0@2|Bacteria,1G6WJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
CMS1_k127_5350358_3	794903.OPIT5_21575	2.006e-70	247.0	COG0345@1|root,COG0345@2|Bacteria,46T4K@74201|Verrucomicrobia,3K7QH@414999|Opitutae	414999|Opitutae	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS1_k127_5350358_5	1121438.JNJA01000001_gene2411	5.426e-61	215.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria,2MBI2@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM isochorismatase hydrolase	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_5350358_1	583355.Caka_1324	4.136e-115	381.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,46UE8@74201|Verrucomicrobia,3K7D3@414999|Opitutae	414999|Opitutae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
CMS1_k127_5350358_0	452637.Oter_3793	9.584e-122	396.0	COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia,3K7QM@414999|Opitutae	414999|Opitutae	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS1_k127_5350358_2	452637.Oter_3791	5.977e-73	253.0	COG1187@1|root,COG1187@2|Bacteria,46SWQ@74201|Verrucomicrobia,3K72J@414999|Opitutae	414999|Opitutae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_5350358_4	1033734.CAET01000056_gene1384	7.574e-63	229.0	COG0369@1|root,COG0369@2|Bacteria,1TP5J@1239|Firmicutes,4HCQI@91061|Bacilli,1ZANY@1386|Bacillus	91061|Bacilli	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
CMS1_k127_5350358_7	666686.B1NLA3E_08545	0.0004604	43.0	COG0369@1|root,COG0369@2|Bacteria,1TP5J@1239|Firmicutes,4HCQI@91061|Bacilli,1ZANY@1386|Bacillus	91061|Bacilli	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU33440	FAD_binding_1,Flavodoxin_1,NAD_binding_1
CMS1_k127_5350358_6	349521.HCH_04845	5.506e-23	112.0	COG3675@1|root,COG3675@2|Bacteria,1NICA@1224|Proteobacteria,1SHG9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Lipase (class 3)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
CMS1_k127_5376990_6	794903.OPIT5_03565	2.029e-36	152.0	COG1388@1|root,COG1388@2|Bacteria,46T90@74201|Verrucomicrobia,3K8BU@414999|Opitutae	414999|Opitutae	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_5376990_3	583355.Caka_3071	1.21e-111	372.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia,3K7ID@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS1_k127_5376990_2	583355.Caka_3072	1.566e-112	374.0	COG0707@1|root,COG0707@2|Bacteria,46UBI@74201|Verrucomicrobia,3KA2U@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS1_k127_5376990_0	452637.Oter_2637	4.698e-215	691.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,3K7P0@414999|Opitutae	414999|Opitutae	M	Cell wall formation	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5376990_5	382464.ABSI01000002_gene4363	9.302e-79	274.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,2IU29@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS1_k127_5376990_7	452637.Oter_2639	3.147e-31	134.0	COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,3K847@414999|Opitutae	414999|Opitutae	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
CMS1_k127_5376990_4	583355.Caka_3076	1.135e-107	364.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia,3K782@414999|Opitutae	414999|Opitutae	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_5376990_1	452637.Oter_2641	7.809e-114	383.0	COG0206@1|root,COG0206@2|Bacteria,46UAJ@74201|Verrucomicrobia,3K7KG@414999|Opitutae	414999|Opitutae	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_537733_2	452637.Oter_1125	1.279e-62	223.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria	452637.Oter_1125|-	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_537733_0	398720.MED217_17145	4.73e-257	811.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1I8HP@117743|Flavobacteriia,2XJZI@283735|Leeuwenhoekiella	976|Bacteroidetes	G	Domain of unknown function (DUF5110)	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
CMS1_k127_537733_3	349520.PPE_00859	2.145e-42	169.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,26QU0@186822|Paenibacillaceae	91061|Bacilli	K	catabolite control protein A	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_537733_1	452637.Oter_1374	8.897e-184	582.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CMS1_k127_5377806_0	382464.ABSI01000011_gene2439	1.815e-165	537.0	COG4585@1|root,COG4585@2|Bacteria,46SBM@74201|Verrucomicrobia,2IV76@203494|Verrucomicrobiae	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS1_k127_5401250_0	880073.Calab_3446	2.766e-76	282.0	COG0642@1|root,COG2205@2|Bacteria	880073.Calab_3446|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5401386_3	382464.ABSI01000011_gene3083	8.647e-07	57.0	2EI2N@1|root,33BU2@2|Bacteria,46WEF@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5401386_2	1437824.BN940_17691	1.092e-47	180.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,3T3RD@506|Alcaligenaceae	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS1_k127_5401386_0	452637.Oter_1916	3.624e-168	537.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,3K7P6@414999|Opitutae	414999|Opitutae	C	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C,Radical_SAM
CMS1_k127_5401386_1	583355.Caka_1978	1.015e-152	494.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,3K72S@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS1_k127_5438095_0	452637.Oter_4432	7.377e-280	870.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia,3K7EV@414999|Opitutae	414999|Opitutae	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS1_k127_5438095_4	452637.Oter_4402	2.886e-13	75.0	COG3678@1|root,COG3678@2|Bacteria,46WX9@74201|Verrucomicrobia	74201|Verrucomicrobia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5438095_3	1292034.OR37_01079	6.602e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,2U89X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5438095_2	517417.Cpar_0446	4.206e-93	315.0	COG0157@1|root,COG0157@2|Bacteria,1FDZQ@1090|Chlorobi	1090|Chlorobi	H	Belongs to the NadC ModD family	-	-	-	ko:K03813	-	-	-	-	ko00000,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS1_k127_5438095_1	382464.ABSI01000008_gene4028	6.037e-98	341.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
CMS1_k127_5467386_5	1089439.KB902239_gene623	4.151e-14	75.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S30E@1236|Gammaproteobacteria,461HN@72273|Thiotrichales	72273|Thiotrichales	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
CMS1_k127_5467386_1	1121094.KB894659_gene2671	1.58e-117	390.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,2FM9N@200643|Bacteroidia,4AKDF@815|Bacteroidaceae	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	bfce	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CMS1_k127_5467386_0	1232410.KI421424_gene1701	4.45e-171	551.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,43SC2@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS1_k127_5467386_3	469617.FUAG_00246	6.646e-24	119.0	COG0300@1|root,COG0300@2|Bacteria,379IH@32066|Fusobacteria	32066|Fusobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_5467386_4	794903.OPIT5_17045	5.165e-20	96.0	COG1302@1|root,COG1302@2|Bacteria,46WB6@74201|Verrucomicrobia,3K8GC@414999|Opitutae	414999|Opitutae	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
CMS1_k127_5467386_2	1396418.BATQ01000166_gene1899	6.131e-42	162.0	COG0352@1|root,COG0352@2|Bacteria,46T6K@74201|Verrucomicrobia,2IUF9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_5467386_6	583355.Caka_2868	8.71e-14	75.0	COG4701@1|root,COG4701@2|Bacteria,46W37@74201|Verrucomicrobia,3K86W@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5475722_4	382464.ABSI01000005_gene1365	2.907e-36	145.0	COG1136@1|root,COG1136@2|Bacteria,46X0J@74201|Verrucomicrobia,2IVS0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_5475722_1	794903.OPIT5_14635	3.815e-113	378.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,3K74K@414999|Opitutae	414999|Opitutae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS1_k127_5475722_0	382464.ABSI01000011_gene3025	1.181e-137	446.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_5475722_3	1144319.PMI16_01052	5.731e-63	233.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,476K9@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PAS fold	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9,Response_reg
CMS1_k127_5475722_2	1121937.AUHJ01000001_gene770	2.407e-84	284.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS1_k127_5487107_2	634956.Geoth_2694	7.962e-12	67.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,4HNQK@91061|Bacilli,1WGCZ@129337|Geobacillus	91061|Bacilli	N	Flagellar hook capping protein - N-terminal region	flgD	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD
CMS1_k127_5487107_1	278957.ABEA03000180_gene2017	1.192e-36	141.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,3K8AV@414999|Opitutae	414999|Opitutae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS1_k127_5487107_0	452637.Oter_2054	4.48e-277	859.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_5487107_3	228399.appser1_11130	0.0002903	52.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1Y7EV@135625|Pasteurellales	135625|Pasteurellales	O	isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
CMS1_k127_5489374_0	794903.OPIT5_24315	4.614e-245	766.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,3K7HP@414999|Opitutae	414999|Opitutae	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_5489374_1	583355.Caka_0712	1.94e-141	463.0	COG0617@1|root,COG0617@2|Bacteria,46UER@74201|Verrucomicrobia,3K732@414999|Opitutae	414999|Opitutae	J	Polynucleotide adenylyltransferase	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS1_k127_5489374_3	794903.OPIT5_28865	7.719e-69	243.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia,3K7X5@414999|Opitutae	414999|Opitutae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_5489374_4	1396141.BATP01000002_gene4806	1.247e-48	181.0	COG0800@1|root,COG0800@2|Bacteria,46V7J@74201|Verrucomicrobia,2IU9V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	KDPG and KHG aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase
CMS1_k127_5489374_7	485918.Cpin_4375	0.0009772	47.0	2AC9S@1|root,311UG@2|Bacteria,4P7SG@976|Bacteroidetes,1IZN6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5489374_2	583355.Caka_1193	2.598e-109	369.0	COG0477@1|root,COG2814@2|Bacteria,46U1F@74201|Verrucomicrobia,3K73V@414999|Opitutae	414999|Opitutae	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5489374_6	382464.ABSI01000021_gene375	3.237e-17	82.0	COG0168@1|root,COG0168@2|Bacteria,46UGP@74201|Verrucomicrobia,2IVEG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
CMS1_k127_5496117_0	572547.Amico_1296	1.372e-125	416.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS1_k127_5496117_1	391624.OIHEL45_15224	5.1e-53	198.0	COG1638@1|root,COG1638@2|Bacteria,1NTFS@1224|Proteobacteria,2U1QM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_552492_0	1122981.AUME01000003_gene1968	7.742e-06	60.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,2FNFE@200643|Bacteroidia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
CMS1_k127_5527664_0	382464.ABSI01000013_gene1832	1.461e-167	533.0	COG2152@1|root,COG2152@2|Bacteria,46URM@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
CMS1_k127_5527664_6	331869.BAL199_00330	1.707e-16	92.0	COG4421@1|root,COG4421@2|Bacteria,1NH8W@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
CMS1_k127_5527664_1	497964.CfE428DRAFT_5282	2.13e-137	447.0	COG0562@1|root,COG0562@2|Bacteria,46SKA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	UDP-galactopyranose mutase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
CMS1_k127_5527664_3	272558.10173556	1.022e-98	344.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus	91061|Bacilli	V	ABC transporter	ygaD	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS1_k127_5527664_2	1158294.JOMI01000004_gene3298	4.58e-115	397.0	COG0535@1|root,COG2327@1|root,COG0535@2|Bacteria,COG2327@2|Bacteria,4NZQY@976|Bacteroidetes	976|Bacteroidetes	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
CMS1_k127_5527664_4	1035193.HMPREF9073_01296	3.54e-68	242.0	COG1216@1|root,COG1216@2|Bacteria,4NK0K@976|Bacteroidetes,1I0UB@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_553209_1	452637.Oter_0815	2.204e-102	352.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia,3K9B6@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
CMS1_k127_553209_3	857087.Metme_2112	2.635e-56	215.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria,1XF24@135618|Methylococcales	135618|Methylococcales	S	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_553209_2	278957.ABEA03000054_gene1134	4.658e-101	341.0	COG0407@1|root,COG0407@2|Bacteria,46UU6@74201|Verrucomicrobia,3K7H3@414999|Opitutae	414999|Opitutae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_553209_0	452637.Oter_0601	1.679e-153	497.0	COG0635@1|root,COG0635@2|Bacteria,46TQX@74201|Verrucomicrobia,3K7DD@414999|Opitutae	414999|Opitutae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_553209_4	1499967.BAYZ01000157_gene595	1.031e-11	77.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
CMS1_k127_553209_5	583355.Caka_3035	4.093e-10	63.0	COG0165@1|root,COG0165@2|Bacteria,46SCX@74201|Verrucomicrobia,3KA2P@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_5547653_4	438753.AZC_2220	3.104e-13	71.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2TVY5@28211|Alphaproteobacteria,3F2DR@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5547653_3	871963.Desdi_1489	1.611e-16	94.0	28QPF@1|root,2ZD50@2|Bacteria,1V2FS@1239|Firmicutes,24IPX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5547653_0	1034943.BN1094_00501	3.089e-119	399.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1JEEN@118969|Legionellales	118969|Legionellales	GM	ABC transporter	wzt	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS1_k127_5547653_2	1453501.JELR01000001_gene2008	3.773e-22	105.0	2CHH4@1|root,32SC0@2|Bacteria,1NPE4@1224|Proteobacteria	1224|Proteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
CMS1_k127_5547653_5	873449.STRCR_0356	7.061e-06	56.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_5547653_1	28229.ND2E_0923	5.088e-32	128.0	COG1280@1|root,COG1280@2|Bacteria,1R3YJ@1224|Proteobacteria,1RSMF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_5571993_5	382464.ABSI01000012_gene2272	8.872e-48	179.0	COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia,2IUBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Putative methyltransferase	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS1_k127_5571993_4	382464.ABSI01000010_gene3686	1.61e-88	298.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,2ITQ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
CMS1_k127_5571993_3	583355.Caka_1793	1.082e-98	332.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia,3K7K6@414999|Opitutae	414999|Opitutae	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_5571993_6	382464.ABSI01000010_gene3688	1.094e-24	107.0	COG0858@1|root,COG0858@2|Bacteria,46TBI@74201|Verrucomicrobia,2IUMI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS1_k127_5571993_0	583355.Caka_1795	5.745e-226	730.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,3K79C@414999|Opitutae	414999|Opitutae	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS1_k127_5571993_1	583355.Caka_1796	1.236e-182	583.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia,3K7UP@414999|Opitutae	414999|Opitutae	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CMS1_k127_5571993_7	332101.JIBU02000025_gene3208	9.592e-08	61.0	28V20@1|root,2ZH5G@2|Bacteria,1UFNF@1239|Firmicutes,24HU4@186801|Clostridia,36JAD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5571993_2	332101.JIBU02000025_gene3209	5.583e-102	343.0	COG0348@1|root,COG0348@2|Bacteria,1VVUA@1239|Firmicutes,24C27@186801|Clostridia,36FBA@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_5
CMS1_k127_5584831_0	1122604.JONR01000001_gene1789	1.409e-51	187.0	COG3181@1|root,COG3181@2|Bacteria,1PHJF@1224|Proteobacteria,1SI76@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_5593274_11	382464.ABSI01000013_gene1702	4.146e-64	225.0	COG1352@1|root,COG1352@2|Bacteria,46VVK@74201|Verrucomicrobia,2IUTZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NT	Methyltransferase, chemotaxis proteins	-	-	-	-	-	-	-	-	-	-	-	-	CheR
CMS1_k127_5593274_9	452637.Oter_0429	9.772e-119	393.0	COG2201@1|root,COG2201@2|Bacteria,46V79@74201|Verrucomicrobia,3K7KJ@414999|Opitutae	414999|Opitutae	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS1_k127_5593274_18	880073.Calab_0425	9.316e-40	168.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
CMS1_k127_5593274_16	1268240.ATFI01000002_gene4894	3.848e-49	183.0	COG3506@1|root,COG3506@2|Bacteria,4NKFW@976|Bacteroidetes,2FQXW@200643|Bacteroidia,4APBX@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG12539 non supervised orthologous group	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
CMS1_k127_5593274_3	794903.OPIT5_04165	9.157e-203	643.0	COG0427@1|root,COG0427@2|Bacteria,46TQC@74201|Verrucomicrobia,3K7AC@414999|Opitutae	414999|Opitutae	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CMS1_k127_5593274_19	794903.OPIT5_02480	1.141e-28	121.0	COG0511@1|root,COG0511@2|Bacteria,46VQF@74201|Verrucomicrobia,3K86E@414999|Opitutae	414999|Opitutae	I	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
CMS1_k127_5593274_21	583355.Caka_0798	5.136e-06	53.0	2BFKC@1|root,329EJ@2|Bacteria,46WGG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
CMS1_k127_5593274_2	452637.Oter_3307	2.863e-229	719.0	COG4799@1|root,COG4799@2|Bacteria,46TGX@74201|Verrucomicrobia,3K75Y@414999|Opitutae	414999|Opitutae	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_5593274_17	644282.Deba_3271	2.311e-42	177.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
CMS1_k127_5593274_15	1313304.CALK_1354	2.625e-51	205.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,DUF3365,MCPsignal,dCache_1
CMS1_k127_5593274_4	1121403.AUCV01000031_gene2833	3.835e-171	562.0	COG1884@1|root,COG1884@2|Bacteria,1NR2K@1224|Proteobacteria,42P1I@68525|delta/epsilon subdivisions,2WKIW@28221|Deltaproteobacteria,2MMUD@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS1_k127_5593274_0	382464.ABSI01000005_gene1225	0.0	1137.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,46TP8@74201|Verrucomicrobia,2IU9J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS1_k127_5593274_13	1121448.DGI_1308	1.634e-62	225.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42N5I@68525|delta/epsilon subdivisions,2WM5T@28221|Deltaproteobacteria,2M9FV@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_31,Radical_SAM
CMS1_k127_5593274_20	44060.JODL01000044_gene3976	4.601e-15	81.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K21886,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,MarR_2
CMS1_k127_5593274_12	794903.OPIT5_25025	2.411e-63	239.0	COG0840@1|root,COG0840@2|Bacteria,46Y7J@74201|Verrucomicrobia,3K92D@414999|Opitutae	414999|Opitutae	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
CMS1_k127_5593274_6	583355.Caka_2556	1.69e-158	510.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,3K7B7@414999|Opitutae	414999|Opitutae	J	PFAM tRNA synthetase class II (G H P and S)	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS1_k127_5593274_8	583355.Caka_0688	2.577e-125	421.0	2F6YF@1|root,33PYZ@2|Bacteria,46TE0@74201|Verrucomicrobia,3K7ET@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5593274_5	583355.Caka_2097	1.326e-164	527.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_5593274_14	452637.Oter_3529	1.386e-58	211.0	COG0546@1|root,COG0546@2|Bacteria,46YH3@74201|Verrucomicrobia,3K9K2@414999|Opitutae	414999|Opitutae	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_5593274_10	1396141.BATP01000003_gene4990	2.606e-103	346.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,46TXQ@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CMS1_k127_5593274_7	452637.Oter_2702	8.038e-126	413.0	COG1092@1|root,COG1092@2|Bacteria,46SJ5@74201|Verrucomicrobia,3K84I@414999|Opitutae	414999|Opitutae	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_5593274_1	1121396.KB893066_gene1580	3.681e-299	932.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MIUG@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_5595819_5	794903.OPIT5_09955	1.014e-55	201.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46USH@74201|Verrucomicrobia,3K738@414999|Opitutae	414999|Opitutae	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS1_k127_5595819_1	452637.Oter_1156	2.619e-190	606.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,3K7BJ@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
CMS1_k127_5595819_4	1283300.ATXB01000001_gene1745	5.822e-59	218.0	COG0665@1|root,COG0665@2|Bacteria,1QJKZ@1224|Proteobacteria,1THMM@1236|Gammaproteobacteria,1XEVH@135618|Methylococcales	135618|Methylococcales	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_5595819_3	517418.Ctha_2308	1.148e-76	268.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1FFK3@1090|Chlorobi	1090|Chlorobi	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
CMS1_k127_5595819_6	517418.Ctha_2308	1.425e-19	97.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1FFK3@1090|Chlorobi	1090|Chlorobi	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
CMS1_k127_5595819_2	583355.Caka_2099	3.934e-130	429.0	COG0486@1|root,COG0486@2|Bacteria,46SIQ@74201|Verrucomicrobia,3K7N8@414999|Opitutae	414999|Opitutae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS1_k127_5595819_0	583355.Caka_2100	1.096e-210	662.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,3K7JB@414999|Opitutae	414999|Opitutae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_5598297_3	278957.ABEA03000091_gene685	4.854e-143	458.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia,3K7PD@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_5598297_0	583355.Caka_0786	1.29e-242	758.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS1_k127_5598297_9	349965.yinte0001_42290	4.208e-38	153.0	COG2966@1|root,COG2966@2|Bacteria,1NH2X@1224|Proteobacteria,1RN1Q@1236|Gammaproteobacteria,41D5B@629|Yersinia	1236|Gammaproteobacteria	S	Putative threonine/serine exporter	yjjP	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015740,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071944	-	-	-	-	-	-	-	-	-	-	ThrE
CMS1_k127_5598297_11	1150621.SMUL_1014	2.823e-16	86.0	COG3610@1|root,COG3610@2|Bacteria,1RAWK@1224|Proteobacteria,42VGV@68525|delta/epsilon subdivisions,2YTS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
CMS1_k127_5598297_2	583355.Caka_1434	3.04e-153	493.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia,3K7CT@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_5598297_6	278957.ABEA03000082_gene2944	3.458e-91	310.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,3K75W@414999|Opitutae	414999|Opitutae	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_5598297_7	583355.Caka_1436	7.12e-88	296.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia,3K7A2@414999|Opitutae	414999|Opitutae	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS1_k127_5598297_10	794903.OPIT5_28150	1.389e-21	103.0	2ES7B@1|root,33JS3@2|Bacteria,46ZHG@74201|Verrucomicrobia,3K9K4@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS1_k127_5598297_5	583355.Caka_2062	2.77e-125	413.0	COG0560@1|root,COG0560@2|Bacteria,46UCT@74201|Verrucomicrobia,3K7I3@414999|Opitutae	414999|Opitutae	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5598297_8	583355.Caka_1952	2.735e-57	203.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia,3K7ZP@414999|Opitutae	414999|Opitutae	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
CMS1_k127_5598297_4	1280681.AUJZ01000014_gene3760	1.122e-140	459.0	COG0688@1|root,COG0688@2|Bacteria	2|Bacteria	I	phosphatidylethanolamine metabolic process	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS1_k127_5598297_1	269797.Mbar_A2978	2.537e-170	546.0	COG4690@1|root,arCOG03602@2157|Archaea,2Y1V5@28890|Euryarchaeota,2NAB9@224756|Methanomicrobia	224756|Methanomicrobia	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
CMS1_k127_5602421_0	203119.Cthe_0554	0.0	1267.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
CMS1_k127_5602421_1	530564.Psta_1941	3.364e-05	50.0	COG1054@1|root,COG1054@2|Bacteria,2J4AW@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0176 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5604957_0	1303518.CCALI_02843	6.699e-208	660.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_5604957_1	1303518.CCALI_02844	2.132e-160	520.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
CMS1_k127_5604957_2	929713.NIASO_09355	1.117e-06	52.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_5607697_2	382464.ABSI01000020_gene295	1.218e-146	483.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia,2ITHG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	GlnD PII-uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GlnD_UR_UTase,GlnE,HD,NTP_transf_2
CMS1_k127_5607697_11	452637.Oter_0643	9.437e-71	253.0	2F1FE@1|root,33UG5@2|Bacteria,46V5X@74201|Verrucomicrobia,3K8V2@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5607697_17	583355.Caka_2277	5.351e-10	68.0	COG3166@1|root,COG3166@2|Bacteria,46WNE@74201|Verrucomicrobia,3K9ZH@414999|Opitutae	414999|Opitutae	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5607697_7	452637.Oter_0639	1.704e-116	392.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02453,ko:K02666	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	CarbopepD_reg_2,Secretin,Secretin_N
CMS1_k127_5607697_0	378806.STAUR_1433	5.082e-165	539.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	SMART Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
CMS1_k127_5607697_10	452637.Oter_3605	1.036e-77	267.0	COG0036@1|root,COG0036@2|Bacteria,46TEK@74201|Verrucomicrobia,3K7FI@414999|Opitutae	414999|Opitutae	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_5607697_18	794903.OPIT5_03350	6.682e-10	67.0	2DI9S@1|root,302GQ@2|Bacteria,46YIP@74201|Verrucomicrobia,3K8AM@414999|Opitutae	414999|Opitutae	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
CMS1_k127_5607697_12	452637.Oter_3602	1.08e-55	209.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,3K7IV@414999|Opitutae	414999|Opitutae	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6
CMS1_k127_5607697_5	583355.Caka_2949	1.167e-122	402.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,3K75X@414999|Opitutae	414999|Opitutae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_5607697_9	583355.Caka_2391	2.257e-81	284.0	COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,3K762@414999|Opitutae	414999|Opitutae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_5607697_14	382464.ABSI01000010_gene3843	4.349e-31	124.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,2IUUU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS1_k127_5607697_6	382464.ABSI01000005_gene1028	1.438e-122	406.0	COG0508@1|root,COG0508@2|Bacteria,46SHZ@74201|Verrucomicrobia,2IU2H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	e3 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_5607697_1	382464.ABSI01000005_gene1029	1.737e-152	489.0	COG0022@1|root,COG0022@2|Bacteria,46S75@74201|Verrucomicrobia,2ITIV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
CMS1_k127_5607697_3	1123070.KB899257_gene2318	4.91e-140	455.0	COG1071@1|root,COG1071@2|Bacteria,46S69@74201|Verrucomicrobia,2ITVF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Transketolase, thiamine diphosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
CMS1_k127_5607697_4	991905.SL003B_1679	3.596e-133	441.0	COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,2TR8M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Mu-like prophage FluMu protein gp28	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
CMS1_k127_5607697_8	240016.ABIZ01000001_gene4490	7.068e-86	299.0	COG4383@1|root,COG4383@2|Bacteria,46V24@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF935
CMS1_k127_5607697_15	240016.ABIZ01000001_gene4491	4.157e-22	106.0	2FJH5@1|root,34B6Q@2|Bacteria,46W9N@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_Pro
CMS1_k127_5607697_16	240016.ABIZ01000001_gene4492	3.622e-20	99.0	2FD8F@1|root,345AF@2|Bacteria,46WA3@74201|Verrucomicrobia	240016.ABIZ01000001_gene4492|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5607697_13	240016.ABIZ01000001_gene1787	8.628e-44	174.0	2F12Z@1|root,33U4G@2|Bacteria,46V8T@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5616499_9	583355.Caka_1269	5.013e-17	81.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia,3K7V0@414999|Opitutae	414999|Opitutae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
CMS1_k127_5616499_8	670292.JH26_23820	4.726e-25	112.0	COG0457@1|root,COG0457@2|Bacteria,1Q5M4@1224|Proteobacteria,2UGJ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
CMS1_k127_5616499_6	1004785.AMBLS11_07285	1.946e-43	168.0	COG1266@1|root,COG1266@2|Bacteria,1RFHC@1224|Proteobacteria,1RZYC@1236|Gammaproteobacteria,46APX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_5616499_5	452637.Oter_0467	6.669e-58	223.0	COG0658@1|root,COG0658@2|Bacteria,46V8U@74201|Verrucomicrobia,3K822@414999|Opitutae	414999|Opitutae	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
CMS1_k127_5616499_0	382464.ABSI01000002_gene4262	3.302e-184	592.0	COG0733@1|root,COG0733@2|Bacteria,46XCF@74201|Verrucomicrobia,2IVFD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
CMS1_k127_5616499_4	583355.Caka_0245	5.144e-92	316.0	COG0795@1|root,COG0795@2|Bacteria,46T0M@74201|Verrucomicrobia,3K73D@414999|Opitutae	414999|Opitutae	S	PFAM permease YjgP YjgQ family protein	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_5616499_3	1565314.OA34_03430	4.749e-99	328.0	COG1346@1|root,COG1346@2|Bacteria,1MXJR@1224|Proteobacteria,42T0P@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM LrgB family protein	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
CMS1_k127_5616499_7	1565314.OA34_03435	1.408e-35	139.0	COG1380@1|root,COG1380@2|Bacteria,1N79K@1224|Proteobacteria,42WWF@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM LrgA family protein	cidA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
CMS1_k127_5616499_10	1120983.KB894570_gene1822	6.088e-16	91.0	2C1AI@1|root,346MG@2|Bacteria,1MXI4@1224|Proteobacteria,2U06V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5616499_1	794903.OPIT5_13955	3.127e-169	545.0	COG0297@1|root,COG0297@2|Bacteria,46TTT@74201|Verrucomicrobia,3K7G7@414999|Opitutae	414999|Opitutae	G	Starch synthase catalytic domain	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS1_k127_5616499_2	452637.Oter_3652	4.576e-115	377.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CMS1_k127_5616499_11	1243664.CAVL020000025_gene1449	2.569e-12	69.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,4HGY2@91061|Bacilli,1ZG7Q@1386|Bacillus	91061|Bacilli	T	response regulator	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS1_k127_5627781_13	794903.OPIT5_01870	2.107e-83	288.0	COG1476@1|root,COG1910@1|root,COG1476@2|Bacteria,COG1910@2|Bacteria,46VY3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,PBP_like
CMS1_k127_5627781_19	452637.Oter_2344	5.389e-10	68.0	COG0810@1|root,COG0810@2|Bacteria,46WRI@74201|Verrucomicrobia,3K8HB@414999|Opitutae	414999|Opitutae	M	Biopolymer transporter TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_5627781_3	338963.Pcar_0151	1.617e-155	514.0	COG1629@1|root,COG4771@2|Bacteria,1MXY7@1224|Proteobacteria,42MSN@68525|delta/epsilon subdivisions,2WIK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_5627781_16	748727.CLJU_c17230	7.604e-65	230.0	COG2014@1|root,COG2014@2|Bacteria,1V16Z@1239|Firmicutes,24DK2@186801|Clostridia,36M4T@31979|Clostridiaceae	186801|Clostridia	S	Putative heavy-metal chelation	-	-	-	ko:K09138	-	-	-	-	ko00000	-	-	-	DUF364,DUF4213
CMS1_k127_5627781_10	748727.CLJU_c17130	3.008e-92	316.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,36EB1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_5627781_17	748727.CLJU_c17160	2.151e-64	234.0	COG1120@1|root,COG1120@2|Bacteria,1UYT8@1239|Firmicutes,24CJY@186801|Clostridia,36FVX@31979|Clostridiaceae	186801|Clostridia	HP	PFAM ABC transporter	-	-	3.6.3.34	ko:K02013,ko:K09820	ko02010,map02010	M00240,M00243	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.15	-	-	ABC_tran
CMS1_k127_5627781_12	509191.AEDB02000020_gene3339	1.284e-86	298.0	COG0614@1|root,COG0614@2|Bacteria,1TQ11@1239|Firmicutes,2482R@186801|Clostridia,3WIH1@541000|Ruminococcaceae	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_5627781_18	485916.Dtox_3476	1.802e-26	115.0	COG1720@1|root,COG1720@2|Bacteria	2|Bacteria	S	tRNA m6t6A37 methyltransferase activity	virR	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	UPF0066
CMS1_k127_5627781_11	794903.OPIT5_01785	4.471e-87	303.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
CMS1_k127_5627781_6	794903.OPIT5_01790	9.451e-113	368.0	COG0378@1|root,COG0378@2|Bacteria	2|Bacteria	KO	nickel cation binding	-	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
CMS1_k127_5627781_7	322710.Avin_00480	7.357e-112	371.0	COG1136@1|root,COG1136@2|Bacteria,1PXKV@1224|Proteobacteria,1S1F2@1236|Gammaproteobacteria	1224|Proteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_5627781_14	583355.Caka_1975	4.181e-80	283.0	COG4148@1|root,COG4148@2|Bacteria,46YZT@74201|Verrucomicrobia,3K86D@414999|Opitutae	414999|Opitutae	P	TOBE domain	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
CMS1_k127_5627781_15	583355.Caka_1974	2.42e-76	262.0	COG4149@1|root,COG4149@2|Bacteria,46TVT@74201|Verrucomicrobia,3K813@414999|Opitutae	414999|Opitutae	P	Molybdate ABC transporter	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS1_k127_5627781_9	382464.ABSI01000021_gene397	5.006e-97	323.0	28IJT@1|root,2Z8KN@2|Bacteria,46U0F@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Dinitrogenase reductase ADP-ribosyltransferase (DRAT)	-	-	-	-	-	-	-	-	-	-	-	-	DRAT
CMS1_k127_5627781_8	926560.KE387023_gene1223	1.087e-102	343.0	COG1397@1|root,COG1397@2|Bacteria,1WN8X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_5627781_4	382464.ABSI01000021_gene410	2.958e-154	491.0	COG1348@1|root,COG1348@2|Bacteria,46SGV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
CMS1_k127_5627781_0	382464.ABSI01000021_gene408	3.057e-298	923.0	COG2710@1|root,COG2710@2|Bacteria,46S6N@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Nitrogenase component 1 type Oxidoreductase	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
CMS1_k127_5627781_2	382464.ABSI01000021_gene407	8.332e-199	636.0	COG2710@1|root,COG2710@2|Bacteria,46SE0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
CMS1_k127_5627781_1	382464.ABSI01000021_gene405	3.163e-222	696.0	COG2710@1|root,COG2710@2|Bacteria,46TQA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
CMS1_k127_5627781_5	382464.ABSI01000021_gene404	7.74e-122	400.0	COG2710@1|root,COG2710@2|Bacteria	2|Bacteria	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein	nifB2	-	-	ko:K02585,ko:K02592	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Oxidored_nitro,Radical_SAM
CMS1_k127_5632617_1	1333998.M2A_1921	1.678e-142	466.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,4BPRN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Cobalamin biosynthesis protein CobT	cobT	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
CMS1_k127_5632617_0	402881.Plav_1713	4.671e-170	539.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,1JN3Y@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Cobaltochelatase CobS subunit N terminal	cobS	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C,CobS_N
CMS1_k127_5632617_2	1101190.ARWB01000001_gene3081	8.418e-10	59.0	COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria,36YCC@31993|Methylocystaceae	28211|Alphaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_5643072_1	406327.Mevan_1556	2.953e-148	473.0	COG0334@1|root,arCOG01352@2157|Archaea,2XU0F@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_5643072_3	1536769.P40081_16555	8.648e-09	64.0	2BS9S@1|root,32XMN@2|Bacteria,1UPPT@1239|Firmicutes,4IV8P@91061|Bacilli,277U8@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
CMS1_k127_5643072_0	794903.OPIT5_04625	1.693e-230	739.0	COG1523@1|root,COG1523@2|Bacteria,46UHI@74201|Verrucomicrobia,3K7P7@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS1_k127_5643072_2	1444711.CCJF01000004_gene2433	3.738e-133	439.0	COG0415@1|root,COG0415@2|Bacteria,2JFX9@204428|Chlamydiae	204428|Chlamydiae	L	DNA photolyase	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS1_k127_5643072_4	459495.SPLC1_S011900	0.0001207	47.0	COG1090@1|root,COG1090@2|Bacteria,1G1NR@1117|Cyanobacteria,1H9DM@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS1_k127_565195_0	313606.M23134_04383	9.656e-54	199.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,HAMP,SpoIIE,TPR_12,TPR_8,Y_Y_Y,dCache_1
CMS1_k127_565195_3	287.DR97_3127	2.14e-05	53.0	2DBYH@1|root,2ZBV5@2|Bacteria,1RA73@1224|Proteobacteria,1S4RG@1236|Gammaproteobacteria,1YI4C@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_565195_2	889378.Spiaf_2711	1.867e-27	115.0	2AD7J@1|root,312WH@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
CMS1_k127_565195_1	517418.Ctha_1885	1.004e-37	154.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1FEYZ@1090|Chlorobi	1090|Chlorobi	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
CMS1_k127_566278_5	1122919.KB905605_gene4580	2.275e-22	102.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HF0T@91061|Bacilli,2750Q@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_566278_3	452637.Oter_3874	6.238e-49	179.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,3K81A@414999|Opitutae	414999|Opitutae	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS1_k127_566278_0	382464.ABSI01000013_gene1747	1.487e-182	592.0	COG0488@1|root,COG0488@2|Bacteria,46V06@74201|Verrucomicrobia,2IU2D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_566278_4	1231392.OCGS_1932	1.828e-32	130.0	2EADY@1|root,334HI@2|Bacteria,1QV05@1224|Proteobacteria	1224|Proteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_566278_1	452637.Oter_2851	8.486e-130	435.0	COG1450@1|root,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,3K7FR@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
CMS1_k127_566278_2	583355.Caka_2414	6.12e-76	267.0	COG1459@1|root,COG1459@2|Bacteria,46UIF@74201|Verrucomicrobia,3K7U0@414999|Opitutae	414999|Opitutae	NU	secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_5663467_2	583355.Caka_0248	5.832e-81	279.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_5663467_3	398512.JQKC01000001_gene2326	8.49e-64	224.0	COG2207@1|root,COG2207@2|Bacteria,1TQDS@1239|Firmicutes,24907@186801|Clostridia,3WGSU@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS1_k127_5663467_0	583355.Caka_2596	1.018e-217	683.0	COG0213@1|root,COG0213@2|Bacteria,46TUU@74201|Verrucomicrobia,3K74X@414999|Opitutae	414999|Opitutae	F	pyrimidine-nucleoside phosphorylase	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS1_k127_5663467_1	583355.Caka_2595	1.394e-209	667.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia,3KA2J@414999|Opitutae	414999|Opitutae	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS1_k127_5663467_10	583355.Caka_2199	2.188e-26	113.0	COG0792@1|root,COG0792@2|Bacteria,46T9J@74201|Verrucomicrobia,3K8A5@414999|Opitutae	414999|Opitutae	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS1_k127_5663467_8	794903.OPIT5_07665	9.036e-31	125.0	COG3824@1|root,COG3824@2|Bacteria,46WK7@74201|Verrucomicrobia,3K8CH@414999|Opitutae	414999|Opitutae	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
CMS1_k127_5663467_9	227377.CBU_1123	2.74e-29	128.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1JDGX@118969|Legionellales	118969|Legionellales	O	DnaJ C terminal domain	cbpA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS1_k127_5663467_7	452637.Oter_0716	1.023e-34	146.0	COG1639@1|root,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_5663467_4	382464.ABSI01000013_gene1698	1.482e-62	219.0	COG1871@1|root,COG1871@2|Bacteria	2|Bacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
CMS1_k127_5663467_6	583355.Caka_2523	8.119e-41	162.0	2F6Y0@1|root,33ZE1@2|Bacteria,46VT9@74201|Verrucomicrobia,3K8B2@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5663467_11	452637.Oter_3743	2.174e-17	88.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,3K89V@414999|Opitutae	414999|Opitutae	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS1_k127_5663467_5	583355.Caka_2467	9.674e-61	214.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,3K7TQ@414999|Opitutae	414999|Opitutae	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_5663760_5	566466.NOR53_304	4.572e-66	231.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1J6DT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	transport system, permease component	yejB	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
CMS1_k127_5663760_1	583355.Caka_1067	2.111e-265	828.0	COG4289@1|root,COG4289@2|Bacteria,46UB4@74201|Verrucomicrobia,3K7DP@414999|Opitutae	414999|Opitutae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5663760_2	583355.Caka_2703	9.345e-213	665.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_5663760_10	661478.OP10G_0131	1.948e-06	51.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_5663760_9	452637.Oter_0238	1.299e-12	70.0	COG0690@1|root,COG0690@2|Bacteria,46WU6@74201|Verrucomicrobia,3K8FP@414999|Opitutae	414999|Opitutae	U	Belongs to the SecE SEC61-gamma family	-	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS1_k127_5663760_3	382464.ABSI01000011_gene2687	5.462e-78	265.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,2IU6S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_5663760_6	382464.ABSI01000011_gene2686	5.633e-60	210.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,2IUAM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS1_k127_5663760_4	583355.Caka_2707	1.011e-71	249.0	COG0081@1|root,COG0081@2|Bacteria,46UQ6@74201|Verrucomicrobia,3K7JU@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_5663760_8	583355.Caka_2708	1.878e-34	138.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,3K7ZE@414999|Opitutae	414999|Opitutae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS1_k127_5663760_7	278957.ABEA03000094_gene4763	1.761e-51	184.0	COG0222@1|root,COG0222@2|Bacteria,46SWC@74201|Verrucomicrobia,3K84B@414999|Opitutae	414999|Opitutae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS1_k127_5663760_0	583355.Caka_2710	0.0	1590.0	COG0085@1|root,COG0085@2|Bacteria,46S8Q@74201|Verrucomicrobia,3K77T@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS1_k127_5688551_0	477184.KYC_08940	1.641e-137	441.0	COG0596@1|root,COG0596@2|Bacteria,1NSXF@1224|Proteobacteria,2VZBR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_5688551_3	1341155.FSS13T_19980	1.636e-96	324.0	COG1215@1|root,COG1215@2|Bacteria,4NFUA@976|Bacteroidetes,1HY1H@117743|Flavobacteriia,2NVCZ@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
CMS1_k127_5688551_4	1279009.ADICEAN_00996	8.86e-55	206.0	COG1283@1|root,COG1283@2|Bacteria,4NMSG@976|Bacteroidetes,47UEZ@768503|Cytophagia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
CMS1_k127_5688551_5	1125863.JAFN01000001_gene2574	1.737e-50	187.0	COG0704@1|root,COG0704@2|Bacteria,1NRGK@1224|Proteobacteria	1224|Proteobacteria	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
CMS1_k127_5688551_2	205922.Pfl01_1382	2.661e-114	395.0	COG1287@1|root,COG1287@2|Bacteria,1RFFI@1224|Proteobacteria	1224|Proteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5688551_1	583355.Caka_2492	1.153e-120	397.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS1_k127_5688551_6	583355.Caka_2493	1.439e-41	157.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,3K84M@414999|Opitutae	414999|Opitutae	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS1_k127_5688551_7	794903.OPIT5_19920	1.194e-35	139.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,3K80Q@414999|Opitutae	414999|Opitutae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_5693019_0	401053.AciPR4_2656	1.53e-301	943.0	COG3669@1|root,COG3669@2|Bacteria,3Y37T@57723|Acidobacteria,2JKVF@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CMS1_k127_5693019_2	1303518.CCALI_02561	3.603e-244	779.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_5693019_7	1227349.C170_16120	2.835e-145	478.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HCT0@91061|Bacilli,27496@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
CMS1_k127_5693019_13	452637.Oter_1388	1.32e-40	157.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
CMS1_k127_5693019_5	1396141.BATP01000040_gene2127	1.605e-158	524.0	COG0515@1|root,COG0515@2|Bacteria,46UX7@74201|Verrucomicrobia,2IVEF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_5693019_9	1396141.BATP01000030_gene3596	1.443e-127	424.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia,2ITRH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_5693019_14	452637.Oter_2367	2.088e-39	151.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5693019_3	452637.Oter_2368	2.878e-213	691.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia,3K7BA@414999|Opitutae	414999|Opitutae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_5693019_1	452637.Oter_3220	9.173e-273	848.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	He_PIG,He_PIG_assoc,Melibiase_2,Melibiase_2_C,NPCBM
CMS1_k127_5693019_4	382464.ABSI01000009_gene3997	1.507e-176	566.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia,2ITNR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CMS1_k127_5693019_8	382464.ABSI01000013_gene1816	3.282e-136	447.0	COG3876@1|root,COG3876@2|Bacteria,46UR1@74201|Verrucomicrobia,2IV8D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS1_k127_5693019_6	1232410.KI421422_gene2000	3.55e-154	505.0	COG0475@1|root,COG1762@1|root,COG0475@2|Bacteria,COG1762@2|Bacteria,1MVGV@1224|Proteobacteria,42WJ6@68525|delta/epsilon subdivisions,2X9V9@28221|Deltaproteobacteria,43V8V@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_5693019_12	926569.ANT_10750	4.958e-53	197.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yigM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_5693019_16	1123508.JH636440_gene2178	5.635e-19	93.0	COG2940@1|root,COG2940@2|Bacteria,2J0Q9@203682|Planctomycetes	203682|Planctomycetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
CMS1_k127_5693019_15	519989.ECTPHS_00964	6.205e-22	98.0	COG1342@1|root,COG1342@2|Bacteria,1N80T@1224|Proteobacteria,1S9DC@1236|Gammaproteobacteria,1WZ10@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
CMS1_k127_5693019_17	690850.Desaf_1817	1.598e-13	76.0	COG2050@1|root,COG2050@2|Bacteria,1NA8E@1224|Proteobacteria,42XJH@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_5693019_10	278957.ABEA03000060_gene3117	1.498e-117	389.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,3K7D5@414999|Opitutae	414999|Opitutae	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS1_k127_5693019_11	517418.Ctha_0870	1.192e-55	206.0	COG0642@1|root,COG2205@2|Bacteria	517418.Ctha_0870|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5704443_0	338963.Pcar_0046	1.661e-79	282.0	COG4625@1|root,COG4870@1|root,COG4625@2|Bacteria,COG4870@2|Bacteria,1MU92@1224|Proteobacteria,42Q0T@68525|delta/epsilon subdivisions,2WM1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
CMS1_k127_5704443_1	504832.OCAR_4817	2.465e-33	131.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,3K02Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CMS1_k127_5704443_2	314278.NB231_17473	4.56e-20	93.0	COG3093@1|root,COG3093@2|Bacteria,1PSY0@1224|Proteobacteria,1TB0E@1236|Gammaproteobacteria,1X1AK@135613|Chromatiales	135613|Chromatiales	K	addiction module antidote protein HigA	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_5704443_3	382464.ABSI01000011_gene2493	7.025e-20	90.0	COG1386@1|root,COG1386@2|Bacteria,46VRU@74201|Verrucomicrobia,2IUTS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Segregation and condensation complex subunit ScpB	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpB
CMS1_k127_5706576_0	452637.Oter_0423	1.619e-109	362.0	COG1536@1|root,COG1536@2|Bacteria,46US0@74201|Verrucomicrobia,3K7R6@414999|Opitutae	414999|Opitutae	N	FliG middle domain	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
CMS1_k127_5706576_3	382464.ABSI01000010_gene3761	5.305e-54	194.0	COG0698@1|root,COG0698@2|Bacteria,46STF@74201|Verrucomicrobia,2IUD9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribose/Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	LacAB_rpiB
CMS1_k127_5706576_2	382464.ABSI01000020_gene317	5.115e-55	205.0	COG1237@1|root,COG1237@2|Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_5706576_1	933262.AXAM01000062_gene944	1.146e-56	226.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria,2MIBZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Peptidase_C14
CMS1_k127_5706576_5	411471.SUBVAR_05424	5.416e-34	152.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_5706576_4	452637.Oter_3497	1.231e-42	161.0	COG2890@1|root,COG2890@2|Bacteria,46SZE@74201|Verrucomicrobia,3K75Z@414999|Opitutae	414999|Opitutae	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	Methyltransf_31
CMS1_k127_5711238_1	583355.Caka_0888	6.209e-89	304.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	hhoA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_5711238_2	583355.Caka_0731	7.87e-67	233.0	COG0703@1|root,COG0703@2|Bacteria,46YZV@74201|Verrucomicrobia,3K80S@414999|Opitutae	414999|Opitutae	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS1_k127_5711238_0	583355.Caka_0740	9.708e-276	858.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia,3K7JS@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CMS1_k127_5711238_3	1304872.JAGC01000009_gene471	1.45e-11	69.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8VA@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5729121_2	583355.Caka_2039	7.467e-122	404.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia,3K7NX@414999|Opitutae	414999|Opitutae	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_5729121_0	583355.Caka_2459	4.344e-257	805.0	COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia,3K75B@414999|Opitutae	414999|Opitutae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS1_k127_5729121_5	96561.Dole_1196	2.462e-08	64.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
CMS1_k127_5729121_1	583355.Caka_2460	7.884e-170	542.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia,3K7MB@414999|Opitutae	414999|Opitutae	H	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_5729121_3	583355.Caka_2461	7.435e-76	263.0	COG0589@1|root,COG0589@2|Bacteria,46V83@74201|Verrucomicrobia,3K7Y4@414999|Opitutae	2|Bacteria	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_5729121_4	67373.JOBF01000014_gene4530	4.673e-22	96.0	COG1162@1|root,COG1162@2|Bacteria,2IMZI@201174|Actinobacteria	201174|Actinobacteria	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
CMS1_k127_5731813_1	278957.ABEA03000180_gene2001	3.957e-59	211.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,3K7PV@414999|Opitutae	414999|Opitutae	H	Protein-arginine kinase	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
CMS1_k127_5731813_2	794903.OPIT5_24185	2.811e-56	201.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia,3K823@414999|Opitutae	414999|Opitutae	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
CMS1_k127_5731813_0	583355.Caka_1065	9.488e-80	270.0	COG0115@1|root,COG0115@2|Bacteria,46S9W@74201|Verrucomicrobia,3K7I4@414999|Opitutae	414999|Opitutae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_5741172_1	794903.OPIT5_25025	4.878e-10	64.0	COG0840@1|root,COG0840@2|Bacteria,46Y7J@74201|Verrucomicrobia,3K92D@414999|Opitutae	414999|Opitutae	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
CMS1_k127_5741172_0	452637.Oter_0815	2.424e-81	290.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia,3K9B6@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
CMS1_k127_57756_3	278957.ABEA03000106_gene1800	7.639e-53	192.0	COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia,3K7BK@414999|Opitutae	414999|Opitutae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_57756_4	382464.ABSI01000010_gene3597	1.072e-41	160.0	COG1376@1|root,COG1376@2|Bacteria,46VRV@74201|Verrucomicrobia,2IUQ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_57756_0	382464.ABSI01000010_gene3596	1.129e-142	459.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia,2ITM6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_57756_1	1396141.BATP01000042_gene1914	8.886e-94	319.0	COG0384@1|root,COG0384@2|Bacteria,46SN8@74201|Verrucomicrobia,2IU9G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS1_k127_57756_2	583355.Caka_2287	4.474e-86	295.0	COG0287@1|root,COG0287@2|Bacteria,46URU@74201|Verrucomicrobia,3K7XP@414999|Opitutae	414999|Opitutae	E	Prephenate dehydrogenase	-	-	1.3.1.12,1.3.1.43	ko:K00220	ko00400,ko00401,ko01100,ko01110,ko01230,map00400,map00401,map01100,map01110,map01230	M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_5782434_11	452637.Oter_4063	2.335e-26	112.0	COG0640@1|root,COG0640@2|Bacteria,46W0M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_5782434_1	596151.DesfrDRAFT_0879	6.951e-149	477.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria,2M8CG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS1_k127_5782434_12	1499967.BAYZ01000050_gene2842	7.719e-21	95.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
CMS1_k127_5782434_9	452637.Oter_4059	3.897e-39	149.0	COG0526@1|root,COG0526@2|Bacteria,46W21@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_5782434_3	452637.Oter_4058	5.928e-99	328.0	COG4232@1|root,COG4232@2|Bacteria,46V2A@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS1_k127_5782434_0	452637.Oter_3670	1.864e-168	535.0	COG0798@1|root,COG0798@2|Bacteria,46YU8@74201|Verrucomicrobia,3K88W@414999|Opitutae	414999|Opitutae	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS1_k127_5782434_6	278957.ABEA03000004_gene4514	9.276e-59	207.0	COG0394@1|root,COG0394@2|Bacteria,46ZFS@74201|Verrucomicrobia,3K835@414999|Opitutae	414999|Opitutae	T	low molecular weight	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_5782434_2	1158607.UAU_04260	2.853e-116	377.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,4AZWT@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS1_k127_5782434_7	1396141.BATP01000060_gene4763	1.844e-48	176.0	COG1733@1|root,COG1733@2|Bacteria,46Z1E@74201|Verrucomicrobia,2IUT9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS1_k127_5782434_4	223283.PSPTO_2507	1.631e-97	328.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,1RPD9@1236|Gammaproteobacteria,1Z7AH@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	GM	NmrA-like family	qorB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
CMS1_k127_5782434_13	537972.ABQU01000030_gene424	9.705e-06	49.0	2A4CB@1|root,30SXZ@2|Bacteria,1PCGS@1224|Proteobacteria,42W82@68525|delta/epsilon subdivisions,2YQMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5782434_5	497964.CfE428DRAFT_2215	1.589e-94	329.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_5782434_10	583355.Caka_1440	3.956e-31	132.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia,3K7Z2@414999|Opitutae	414999|Opitutae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS1_k127_5782434_8	583355.Caka_2036	1.732e-46	174.0	2F9J5@1|root,341VF@2|Bacteria,46VQB@74201|Verrucomicrobia,3K7XZ@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
CMS1_k127_580206_1	583355.Caka_1897	7.323e-182	576.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_580206_4	583355.Caka_1896	1.7e-140	462.0	COG1160@1|root,COG1160@2|Bacteria,46SJY@74201|Verrucomicrobia,3K77B@414999|Opitutae	414999|Opitutae	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS1_k127_580206_8	794903.OPIT5_24215	3.462e-75	263.0	COG4223@1|root,COG4223@2|Bacteria,46VW0@74201|Verrucomicrobia,3K74I@414999|Opitutae	414999|Opitutae	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_580206_7	452637.Oter_2842	5.605e-83	286.0	COG0223@1|root,COG0223@2|Bacteria,46SKS@74201|Verrucomicrobia,3K7UM@414999|Opitutae	414999|Opitutae	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_580206_9	1223523.H340_22326	2.561e-66	239.0	COG2357@1|root,COG2357@2|Bacteria,2I30R@201174|Actinobacteria	201174|Actinobacteria	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_580206_3	382464.ABSI01000007_gene4181	1.576e-155	503.0	COG3345@1|root,COG3345@2|Bacteria,46UW0@74201|Verrucomicrobia,2IWQ9@203494|Verrucomicrobiae	2|Bacteria	G	Melibiase	rafA	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0051069,GO:0051682,GO:0071704,GO:1901575	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Dockerin_1,Glyco_hydro_36C,Glyco_hydro_36N,Melibiase,Melibiase_2,Melibiase_2_C
CMS1_k127_580206_2	382464.ABSI01000023_gene519	3.433e-179	572.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,2ITM3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_580206_5	583355.Caka_2804	2.264e-130	423.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,3K7JX@414999|Opitutae	414999|Opitutae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_580206_6	1232410.KI421413_gene495	8.591e-108	372.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,43TRK@69541|Desulfuromonadales	28221|Deltaproteobacteria	CJ	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
CMS1_k127_580206_10	497964.CfE428DRAFT_2569	4.019e-36	142.0	COG1225@1|root,COG1225@2|Bacteria,46VGB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_580206_11	1048983.EL17_00810	3.766e-19	100.0	28J0D@1|root,2Z8XK@2|Bacteria,4NJPF@976|Bacteroidetes,47PJN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
CMS1_k127_580206_0	278957.ABEA03000135_gene1781	6.312e-260	831.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,3K7J2@414999|Opitutae	414999|Opitutae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
CMS1_k127_5817186_5	1282360.ABAC460_06385	1.737e-08	55.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria	1224|Proteobacteria	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281,2.4.1.339,2.4.1.340	ko:K16212,ko:K20885	-	-	R09943,R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS1_k127_5817186_3	580331.Thit_1994	2.637e-40	158.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,42G1I@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_5817186_1	266940.Krad_2776	1.865e-103	358.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.1.3.1,3.1.3.5	ko:K01077,ko:K01081	ko00230,ko00240,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00730,map00760,map00790,map01100,map01110,map02020	M00126	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	5_nucleotid_C,CHRD,DUF4114,Exo_endo_phos,HemolysinCabind,Phytase-like
CMS1_k127_5817186_4	382464.ABSI01000013_gene1623	1.102e-39	156.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,2IUII@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_5817186_2	794903.OPIT5_18115	1.651e-75	263.0	COG0483@1|root,COG0483@2|Bacteria,46V41@74201|Verrucomicrobia,3K741@414999|Opitutae	414999|Opitutae	G	Inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
CMS1_k127_5817186_0	452637.Oter_4620	2.551e-106	349.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia,3K74G@414999|Opitutae	414999|Opitutae	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5848024_2	382464.ABSI01000017_gene96	3.213e-74	259.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	hpaA	-	-	ko:K02099,ko:K02508,ko:K07506,ko:K18954	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,Cupin_2,HTH_18
CMS1_k127_5848024_3	743722.Sph21_4052	6.621e-54	201.0	COG0546@1|root,COG0546@2|Bacteria,4NM4F@976|Bacteroidetes,1IXMX@117747|Sphingobacteriia	976|Bacteroidetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_5848024_0	694427.Palpr_0844	2.778e-153	499.0	COG1102@1|root,COG2364@1|root,COG1102@2|Bacteria,COG2364@2|Bacteria,4NMT3@976|Bacteroidetes,2G3EX@200643|Bacteroidia,23221@171551|Porphyromonadaceae	976|Bacteroidetes	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
CMS1_k127_5848024_1	665571.STHERM_c17360	5.608e-93	315.0	COG2152@1|root,COG2152@2|Bacteria,2J65K@203691|Spirochaetes	203691|Spirochaetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS1_k127_5849395_0	583355.Caka_1872	2.956e-138	457.0	COG1418@1|root,COG1418@2|Bacteria,46U1S@74201|Verrucomicrobia,3K7E0@414999|Opitutae	414999|Opitutae	A	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS1_k127_5849395_2	373994.Riv7116_0485	2.208e-40	168.0	COG2244@1|root,COG2244@2|Bacteria,1G2NK@1117|Cyanobacteria,1HP4C@1161|Nostocales	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS1_k127_5849395_1	583355.Caka_1714	7.529e-43	169.0	COG0457@1|root,COG0457@2|Bacteria	583355.Caka_1714|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5864251_0	452637.Oter_2799	3.664e-186	604.0	COG0417@1|root,COG0417@2|Bacteria,46UHT@74201|Verrucomicrobia,3K7Q3@414999|Opitutae	414999|Opitutae	L	DNA polymerase type-B family	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B,DNA_pol_B_exo1
CMS1_k127_5864251_2	452637.Oter_3085	3.477e-91	317.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia,3K7NA@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_5864251_1	583355.Caka_1448	2.148e-142	457.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_5885034_16	1267535.KB906767_gene1032	1.249e-50	189.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_5885034_18	351348.Maqu_2931	2.204e-28	121.0	28NG2@1|root,2ZBI9@2|Bacteria,1R98N@1224|Proteobacteria,1RYRF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5885034_0	452637.Oter_2103	9.665e-197	624.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	414999|Opitutae	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5885034_10	497964.CfE428DRAFT_6299	7.438e-74	257.0	COG1119@1|root,COG1119@2|Bacteria,46SN3@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS1_k127_5885034_7	583355.Caka_2244	1.793e-94	316.0	COG0413@1|root,COG0413@2|Bacteria,46TUD@74201|Verrucomicrobia,3K7W6@414999|Opitutae	414999|Opitutae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS1_k127_5885034_6	382464.ABSI01000012_gene2254	9.775e-103	344.0	COG0240@1|root,COG0240@2|Bacteria,46SQJ@74201|Verrucomicrobia,2ITRT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS1_k127_5885034_20	452637.Oter_1796	7.916e-13	82.0	COG1287@1|root,COG1287@2|Bacteria,46TK2@74201|Verrucomicrobia,3K85X@414999|Opitutae	74201|Verrucomicrobia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5885034_17	536227.CcarbDRAFT_3417	5.069e-35	141.0	COG0655@1|root,COG0655@2|Bacteria,1UHW0@1239|Firmicutes,24FZ0@186801|Clostridia,36JW5@31979|Clostridiaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,Flavodoxin_2
CMS1_k127_5885034_4	118173.KB235914_gene999	3.146e-104	342.0	COG1215@1|root,COG1215@2|Bacteria,1GHF8@1117|Cyanobacteria,1H7FV@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5885034_2	452637.Oter_4632	2.57e-123	407.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,3K7BM@414999|Opitutae	414999|Opitutae	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS1_k127_5885034_3	382464.ABSI01000011_gene3051	1.041e-114	387.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,2ITH1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CMS1_k127_5885034_15	278957.ABEA03000097_gene781	8.644e-53	200.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,3K7WR@414999|Opitutae	414999|Opitutae	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS1_k127_5885034_8	382464.ABSI01000005_gene1193	3.083e-90	304.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,2IU01@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_5885034_19	1282361.ABAC402_09435	5.215e-24	106.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS1_k127_5885034_12	583355.Caka_1882	3.325e-71	245.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
CMS1_k127_5885034_1	382464.ABSI01000013_gene1638	4.133e-167	542.0	COG0318@1|root,COG0318@2|Bacteria,46XHF@74201|Verrucomicrobia,2IVXI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CMS1_k127_5885034_5	583355.Caka_2479	4.128e-104	349.0	COG0451@1|root,COG0451@2|Bacteria,46UBJ@74201|Verrucomicrobia,3K7JK@414999|Opitutae	414999|Opitutae	M	3-beta hydroxysteroid dehydrogenase	-	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
CMS1_k127_5885034_14	452637.Oter_0632	2.579e-54	194.0	COG0432@1|root,COG0432@2|Bacteria,46V31@74201|Verrucomicrobia,3K83Z@414999|Opitutae	414999|Opitutae	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_5885034_9	583355.Caka_1846	1.511e-80	283.0	COG0265@1|root,COG0265@2|Bacteria,46T0K@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_5885034_21	452637.Oter_0634	3.1e-05	53.0	2AXA3@1|root,31P96@2|Bacteria,46XVB@74201|Verrucomicrobia,3K8DE@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5885034_11	794903.OPIT5_12125	2.239e-72	251.0	COG1595@1|root,COG1595@2|Bacteria,46TFV@74201|Verrucomicrobia,3K7DZ@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5885034_13	583355.Caka_1312	2.215e-60	217.0	COG2804@1|root,COG2804@2|Bacteria,46TEW@74201|Verrucomicrobia,3K94U@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_5886801_3	1121479.AUBS01000008_gene1015	4.789e-74	259.0	COG3591@1|root,COG3591@2|Bacteria,1MXUN@1224|Proteobacteria,2VF02@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS1_k127_5886801_2	1417296.U879_06820	1.05e-92	310.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
CMS1_k127_5886801_0	1353537.TP2_16265	2.037e-222	701.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,2XNNP@285107|Thioclava	28211|Alphaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	rhbB	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS1_k127_5886801_4	1417296.U879_07945	0.0003987	44.0	COG3316@1|root,COG3316@2|Bacteria,1NC6Z@1224|Proteobacteria,2UFQ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5886801_1	633131.TR2A62_0093	1.741e-97	323.0	COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
CMS1_k127_5897195_1	382464.ABSI01000002_gene4281	3.519e-138	446.0	COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,2ITKK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_5897195_3	246194.CHY_1786	3.321e-72	250.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS1_k127_5897195_2	583355.Caka_2487	2.682e-101	339.0	COG0052@1|root,COG0052@2|Bacteria,46SNG@74201|Verrucomicrobia,3K7D6@414999|Opitutae	414999|Opitutae	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS1_k127_5897195_0	1047013.AQSP01000092_gene315	2.372e-211	691.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_5926941_0	316067.Geob_2948	3.417e-195	623.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_5926941_1	316067.Geob_2951	6.66e-96	323.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ00@28221|Deltaproteobacteria,43UQW@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5930696_0	1122997.AUDD01000004_gene1247	1.519e-127	415.0	COG0171@1|root,COG0171@2|Bacteria,2HY6N@201174|Actinobacteria,4DT0Z@85009|Propionibacteriales	201174|Actinobacteria	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
CMS1_k127_5930696_1	909663.KI867150_gene2281	4.842e-68	242.0	COG2755@1|root,COG2755@2|Bacteria,1RKNW@1224|Proteobacteria,42SMH@68525|delta/epsilon subdivisions,2WPP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5942530_3	1232410.KI421413_gene865	4.384e-71	244.0	COG3829@1|root,COG4624@1|root,COG3829@2|Bacteria,COG4624@2|Bacteria,1R8T5@1224|Proteobacteria,42Q3W@68525|delta/epsilon subdivisions,2WK6C@28221|Deltaproteobacteria,43TPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Domains FehydlgC, FeS, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,HTH_8,Sigma54_activat
CMS1_k127_5942530_0	579405.Dd703_1357	5.302e-100	338.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,PilZ
CMS1_k127_5942530_4	1267535.KB906767_gene42	3.013e-38	156.0	28MCN@1|root,2ZAQR@2|Bacteria,3Y8K1@57723|Acidobacteria,2JNFU@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5942530_6	706587.Desti_1336	1.281e-19	93.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,42VEJ@68525|delta/epsilon subdivisions,2WS0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
CMS1_k127_5942530_1	292564.Cyagr_3093	5.846e-78	266.0	COG0500@1|root,COG2226@2|Bacteria,1G3RV@1117|Cyanobacteria,22TFH@167375|Cyanobium	1117|Cyanobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5942530_2	1163408.UU9_09252	1.41e-75	263.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RYX7@1236|Gammaproteobacteria,1XCRJ@135614|Xanthomonadales	135614|Xanthomonadales	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
CMS1_k127_5942530_5	666685.R2APBS1_2749	6.128e-27	113.0	COG2963@1|root,COG2963@2|Bacteria,1N1CG@1224|Proteobacteria,1SAIC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
CMS1_k127_5942530_7	1137269.AZWL01000025_gene68	3.914e-16	83.0	2B7BH@1|root,320EM@2|Bacteria,2H42D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5949257_3	452637.Oter_4013	3.137e-56	204.0	COG0707@1|root,COG0707@2|Bacteria,46UKT@74201|Verrucomicrobia,3K85S@414999|Opitutae	414999|Opitutae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C
CMS1_k127_5949257_1	794903.OPIT5_15220	1.31e-133	437.0	COG0304@1|root,COG0304@2|Bacteria,46UQ4@74201|Verrucomicrobia,3K78C@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_5949257_2	452637.Oter_4016	1.537e-70	248.0	COG0236@1|root,COG0764@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria,46XU4@74201|Verrucomicrobia,3K848@414999|Opitutae	414999|Opitutae	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_5949257_0	278957.ABEA03000115_gene576	6.636e-164	520.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia,3K756@414999|Opitutae	414999|Opitutae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_5949257_7	927658.AJUM01000037_gene1950	8.842e-11	69.0	2DPG2@1|root,32UM0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5949257_5	583355.Caka_0694	8.014e-40	151.0	COG1959@1|root,COG1959@2|Bacteria,46VNQ@74201|Verrucomicrobia,3K872@414999|Opitutae	414999|Opitutae	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_5949257_4	1336208.JADY01000002_gene173	1.507e-44	171.0	COG0483@1|root,COG0483@2|Bacteria,1MZUW@1224|Proteobacteria,2UTGC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_5949257_6	278957.ABEA03000161_gene138	2.257e-11	67.0	COG2165@1|root,COG2165@2|Bacteria,46W6A@74201|Verrucomicrobia,3K883@414999|Opitutae	414999|Opitutae	NU	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_5983929_3	926550.CLDAP_29090	3.009e-16	93.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
CMS1_k127_5983929_2	583355.Caka_3036	1.149e-45	173.0	COG0127@1|root,COG0127@2|Bacteria,46VGG@74201|Verrucomicrobia,3K87U@414999|Opitutae	414999|Opitutae	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS1_k127_5983929_0	1229172.JQFA01000004_gene764	1.767e-141	452.0	COG0447@1|root,COG0447@2|Bacteria,1G10D@1117|Cyanobacteria,1H70Q@1150|Oscillatoriales	1117|Cyanobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.menB	ECH_1
CMS1_k127_5983929_1	926550.CLDAP_00570	8.536e-108	387.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,2G7J9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
CMS1_k127_6003482_0	794903.OPIT5_29135	5.601e-211	667.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia,3K7A8@414999|Opitutae	414999|Opitutae	C	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS1_k127_6003482_2	583355.Caka_0803	5.488e-41	157.0	COG2096@1|root,COG2096@2|Bacteria,46WCM@74201|Verrucomicrobia,3K9T8@414999|Opitutae	414999|Opitutae	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS1_k127_6003482_1	404380.Gbem_1465	8.858e-128	413.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,43TQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
CMS1_k127_6003482_3	1234595.C725_1777	3.431e-07	52.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,4BPP4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_6012399_3	1121933.AUHH01000038_gene1552	1.612e-45	176.0	COG0676@1|root,COG0676@2|Bacteria,2IIUH@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
CMS1_k127_6012399_7	1035197.HMPREF9999_00896	2.294e-05	51.0	COG2259@1|root,COG2259@2|Bacteria,4NSHH@976|Bacteroidetes,2FTHJ@200643|Bacteroidia	976|Bacteroidetes	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_6012399_1	583355.Caka_2419	2.699e-133	431.0	COG0451@1|root,COG0451@2|Bacteria,46US6@74201|Verrucomicrobia,3K78N@414999|Opitutae	414999|Opitutae	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_6012399_2	583355.Caka_2409	7.807e-52	192.0	COG0496@1|root,COG0496@2|Bacteria,46VWW@74201|Verrucomicrobia,3K79M@414999|Opitutae	414999|Opitutae	S	Survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS1_k127_6012399_5	382464.ABSI01000010_gene3771	1.042e-34	139.0	2FBS3@1|root,343WW@2|Bacteria,46X6J@74201|Verrucomicrobia,2IUQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6012399_0	382464.ABSI01000011_gene3075	5.293e-159	514.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6012399_6	765913.ThidrDRAFT_0627	1.003e-32	137.0	COG0500@1|root,COG2226@2|Bacteria,1N3VV@1224|Proteobacteria,1SCTZ@1236|Gammaproteobacteria,1WZXH@135613|Chromatiales	135613|Chromatiales	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6012399_4	583355.Caka_2342	4.513e-45	166.0	COG0327@1|root,COG0327@2|Bacteria,46U5H@74201|Verrucomicrobia,3K7NT@414999|Opitutae	414999|Opitutae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS1_k127_6042272_0	382464.ABSI01000011_gene2718	3.173e-159	516.0	COG2317@1|root,COG2317@2|Bacteria,46TJB@74201|Verrucomicrobia,2IU0U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carboxypeptidase Taq (M32) metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M32
CMS1_k127_6045160_0	382464.ABSI01000013_gene1700	8.86e-105	358.0	COG3437@1|root,COG3437@2|Bacteria,46UU1@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
CMS1_k127_6045160_2	452637.Oter_1508	3.453e-08	64.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_C
CMS1_k127_6045160_1	357809.Cphy_1473	8.924e-57	210.0	COG0627@1|root,COG0627@2|Bacteria,1VJ65@1239|Firmicutes	1239|Firmicutes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS1_k127_6054088_0	583355.Caka_0695	0.0	1052.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_6057481_1	909943.HIMB100_00005080	3.073e-123	404.0	COG0537@1|root,COG1403@1|root,COG0537@2|Bacteria,COG1403@2|Bacteria,1N3EA@1224|Proteobacteria,2UN7N@28211|Alphaproteobacteria,4BSEW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	FGV	Scavenger mRNA decapping enzyme C-term binding	-	-	-	-	-	-	-	-	-	-	-	-	HIT,HNH
CMS1_k127_6057481_0	511.JT27_17055	3.48e-161	534.0	COG0467@1|root,COG0782@1|root,COG1112@1|root,COG0467@2|Bacteria,COG0782@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,2VHWC@28216|Betaproteobacteria,3T4F2@506|Alcaligenaceae	28216|Betaproteobacteria	L	COG1112 Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559,GreA_GreB,WGR
CMS1_k127_606937_0	382464.ABSI01000023_gene575	2.431e-101	357.0	COG0128@1|root,COG0128@2|Bacteria,46SFD@74201|Verrucomicrobia,2ITVM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS1_k127_606937_1	583355.Caka_2285	1.707e-61	237.0	COG0283@1|root,COG0283@2|Bacteria,46V54@74201|Verrucomicrobia,3K7W8@414999|Opitutae	414999|Opitutae	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS1_k127_6069825_1	880072.Desac_1794	1.796e-149	488.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43DA8@68525|delta/epsilon subdivisions,2X8GV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
CMS1_k127_6069825_3	880072.Desac_1796	1.574e-51	192.0	2C8AD@1|root,32RKP@2|Bacteria,1N2M5@1224|Proteobacteria,430H8@68525|delta/epsilon subdivisions,2WVXD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Gas vesicle synthesis protein GvpL GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
CMS1_k127_6069825_0	357804.Ping_1247	2.291e-298	930.0	COG1222@1|root,COG1222@2|Bacteria,1NI7U@1224|Proteobacteria,1RY0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
CMS1_k127_6069825_4	880072.Desac_1798	9.63e-46	176.0	COG0071@1|root,COG0071@2|Bacteria,1RI2P@1224|Proteobacteria,430UN@68525|delta/epsilon subdivisions,2WVUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	GvpH
CMS1_k127_6069825_2	247490.KSU1_B0162	9.786e-117	391.0	COG2204@1|root,COG2204@2|Bacteria,2IXIQ@203682|Planctomycetes	203682|Planctomycetes	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6082511_0	452637.Oter_4220	0.0	1108.0	COG3459@1|root,COG3459@2|Bacteria	2|Bacteria	G	carbohydrate binding	cbpA	-	2.4.1.333	ko:K21298	-	-	-	-	ko00000,ko01000	-	GH94	-	Glyco_hydro_36,Glyco_transf_36
CMS1_k127_6082511_1	935863.AWZR01000003_gene2778	3.955e-270	851.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1X4AX@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_6082511_2	861299.J421_1673	6.107e-181	580.0	COG5368@1|root,COG5368@2|Bacteria	2|Bacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
CMS1_k127_6082511_3	452637.Oter_4221	2.402e-129	429.0	COG2211@1|root,COG2211@2|Bacteria,46YMU@74201|Verrucomicrobia,3K7KX@414999|Opitutae	414999|Opitutae	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS1_k127_6087258_3	452637.Oter_3946	2.86e-41	159.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690,ko:K09691,ko:K09692	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC2_membrane
CMS1_k127_6087258_1	583355.Caka_2053	1.585e-220	713.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia,3K7AY@414999|Opitutae	414999|Opitutae	D	FtsK/SpoIIIE family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_6087258_2	794903.OPIT5_10690	5.052e-116	381.0	COG1482@1|root,COG1482@2|Bacteria,46SVM@74201|Verrucomicrobia,3K78T@414999|Opitutae	414999|Opitutae	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS1_k127_6087258_0	562970.Btus_2813	1.271e-221	720.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,27856@186823|Alicyclobacillaceae	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_6087258_5	583355.Caka_2982	4.715e-16	78.0	COG0267@1|root,COG0267@2|Bacteria,46T91@74201|Verrucomicrobia,3K8F1@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS1_k127_6087258_4	1502770.JQMG01000001_gene1200	1.966e-39	149.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,2VU4A@28216|Betaproteobacteria,2KN71@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Small Multidrug Resistance protein	-	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
CMS1_k127_6101723_2	398767.Glov_1987	3.692e-67	255.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS1_k127_6101723_0	452637.Oter_3479	0.0	1142.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_6101723_1	391612.CY0110_02712	1.607e-85	293.0	COG0641@1|root,COG0641@2|Bacteria,1FZZY@1117|Cyanobacteria	1117|Cyanobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_6112464_2	1396418.BATQ01000044_gene6481	1.197e-14	79.0	COG0268@1|root,COG0268@2|Bacteria,46WWC@74201|Verrucomicrobia,2IV02@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS1_k127_6112464_0	382464.ABSI01000013_gene1775	1.388e-36	149.0	COG0564@1|root,COG0564@2|Bacteria,46VMI@74201|Verrucomicrobia	74201|Verrucomicrobia	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
CMS1_k127_6112464_1	1408433.JHXV01000023_gene3338	9.378e-22	100.0	COG3344@1|root,COG3344@2|Bacteria,4NGJQ@976|Bacteroidetes,1I0E3@117743|Flavobacteriia	976|Bacteroidetes	L	RNA-directed DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
CMS1_k127_6118876_1	324057.Pjdr2_2864	6.166e-21	107.0	COG0747@1|root,COG2247@1|root,COG3408@1|root,COG0747@2|Bacteria,COG2247@2|Bacteria,COG3408@2|Bacteria,1UV7A@1239|Firmicutes,4HUA4@91061|Bacilli,26WF8@186822|Paenibacillaceae	91061|Bacilli	E	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,SLH
CMS1_k127_6118876_0	583355.Caka_1301	1.163e-239	755.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia,3K7T0@414999|Opitutae	414999|Opitutae	T	GTP-binding protein	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_6134641_0	583355.Caka_1614	5.148e-202	636.0	COG0058@1|root,COG0058@2|Bacteria,46S5T@74201|Verrucomicrobia,3K731@414999|Opitutae	414999|Opitutae	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
CMS1_k127_6134641_8	469383.Cwoe_1098	5.084e-42	161.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria,4CTE0@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_6134641_2	1499967.BAYZ01000152_gene1435	8.178e-116	387.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS1_k127_6134641_5	794903.OPIT5_10615	6.096e-98	329.0	COG1989@1|root,COG1989@2|Bacteria,46UC3@74201|Verrucomicrobia,3K7MV@414999|Opitutae	414999|Opitutae	NOU	peptidase A24A prepilin type IV	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS1_k127_6134641_6	583355.Caka_0415	2.482e-66	238.0	COG0169@1|root,COG0169@2|Bacteria,46SVF@74201|Verrucomicrobia,3K7SU@414999|Opitutae	414999|Opitutae	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
CMS1_k127_6134641_7	1279038.KB907342_gene2580	2.075e-61	219.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,2U6J6@28211|Alphaproteobacteria,2JRI9@204441|Rhodospirillales	204441|Rhodospirillales	Q	biosynthesis protein	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS1_k127_6134641_11	583355.Caka_3134	1.822e-11	70.0	COG1934@1|root,COG1934@2|Bacteria,46WSW@74201|Verrucomicrobia,3K8DV@414999|Opitutae	414999|Opitutae	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	LptC
CMS1_k127_6134641_10	382464.ABSI01000010_gene3767	4.076e-13	77.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2
CMS1_k127_6134641_4	583355.Caka_3135	1.607e-105	347.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,3K77F@414999|Opitutae	414999|Opitutae	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
CMS1_k127_6134641_9	452637.Oter_1776	7.468e-17	89.0	COG0398@1|root,COG0398@2|Bacteria,46W3H@74201|Verrucomicrobia,3K8BN@414999|Opitutae	414999|Opitutae	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_6134641_3	794903.OPIT5_07070	1.039e-114	384.0	COG1570@1|root,COG1570@2|Bacteria,46SCN@74201|Verrucomicrobia,3K7JQ@414999|Opitutae	414999|Opitutae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS1_k127_6134641_1	1396418.BATQ01000136_gene3670	1.506e-180	578.0	COG0015@1|root,COG0015@2|Bacteria,46UUE@74201|Verrucomicrobia,2ITG6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS1_k127_6164833_5	945713.IALB_0421	3.655e-93	310.0	COG1294@1|root,COG1294@2|Bacteria	2|Bacteria	C	oxidative phosphorylation	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120	Cyt_bd_oxida_II
CMS1_k127_6164833_3	945713.IALB_0420	1.304e-180	576.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
CMS1_k127_6164833_8	866536.Belba_3624	1.027e-06	55.0	COG0745@1|root,COG0745@2|Bacteria,4NSHT@976|Bacteroidetes,47REC@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_6164833_1	706587.Desti_4937	1.112e-207	668.0	COG1222@1|root,COG1222@2|Bacteria,1NI7U@1224|Proteobacteria,43CSE@68525|delta/epsilon subdivisions,2WUG3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA
CMS1_k127_6164833_2	518766.Rmar_2339	5.048e-194	614.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1FJ01@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein	metZ	-	2.5.1.49	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01287,R01288,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_6164833_6	880072.Desac_1796	7.345e-32	136.0	2C8AD@1|root,32RKP@2|Bacteria,1N2M5@1224|Proteobacteria,430H8@68525|delta/epsilon subdivisions,2WVXD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Gas vesicle synthesis protein GvpL GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
CMS1_k127_6164833_7	104623.Ser39006_00716	1.156e-11	69.0	COG0745@1|root,COG0745@2|Bacteria,1NE6I@1224|Proteobacteria	1224|Proteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_6164833_0	1173028.ANKO01000017_gene217	7.915e-235	739.0	COG0028@1|root,COG0028@2|Bacteria,1G2XN@1117|Cyanobacteria	1117|Cyanobacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_6164833_4	573061.Clocel_0438	1.114e-110	361.0	COG0693@1|root,COG0693@2|Bacteria,1UDUN@1239|Firmicutes,24Y5U@186801|Clostridia,36U4E@31979|Clostridiaceae	2|Bacteria	S	PFAM ThiJ PfpI domain-containing protein	-	-	3.5.1.124	ko:K03152,ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI,ThiJ_like
CMS1_k127_6167163_2	382464.ABSI01000005_gene1278	1.358e-193	610.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_6167163_9	1120970.AUBZ01000003_gene182	1.052e-55	208.0	COG0463@1|root,COG0463@2|Bacteria,1RBHD@1224|Proteobacteria,1S3K4@1236|Gammaproteobacteria,4686Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6167163_1	1124780.ANNU01000032_gene1226	1.836e-197	634.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,47JV2@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
CMS1_k127_6167163_5	583355.Caka_1955	5.489e-153	490.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia,3K7S9@414999|Opitutae	414999|Opitutae	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_6167163_13	713587.THITH_02300	6.673e-31	124.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CMS1_k127_6167163_12	1173020.Cha6605_1561	3.008e-37	147.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
CMS1_k127_6167163_0	794903.OPIT5_04815	2.579e-205	651.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,3K7KQ@414999|Opitutae	414999|Opitutae	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_6167163_11	1187851.A33M_0230	9.363e-47	173.0	2DN8P@1|root,32W46@2|Bacteria,1RJ0F@1224|Proteobacteria,2UM54@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial inner membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
CMS1_k127_6167163_10	583355.Caka_1716	1.572e-53	200.0	COG0500@1|root,COG2226@2|Bacteria,46V7S@74201|Verrucomicrobia,3K7ZC@414999|Opitutae	414999|Opitutae	Q	PFAM Methionine biosynthesis MetW protein	-	-	-	-	-	-	-	-	-	-	-	-	MetW
CMS1_k127_6167163_4	794903.OPIT5_09495	1.659e-163	522.0	COG2021@1|root,COG2021@2|Bacteria,46U58@74201|Verrucomicrobia,3K7TJ@414999|Opitutae	414999|Opitutae	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_6167163_3	452637.Oter_2706	1.674e-190	603.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,3K7NC@414999|Opitutae	414999|Opitutae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_6167163_8	983548.Krodi_1432	1.152e-56	208.0	COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,1HYZ6@117743|Flavobacteriia,37EP1@326319|Dokdonia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_6167163_6	316274.Haur_4586	1.212e-114	379.0	COG0667@1|root,COG0667@2|Bacteria,2G7TU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_6167163_14	706587.Desti_1705	4.665e-28	116.0	COG2840@1|root,COG2840@2|Bacteria,1QX48@1224|Proteobacteria,43BWQ@68525|delta/epsilon subdivisions,2X77I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS1_k127_6167163_7	497964.CfE428DRAFT_4021	1.056e-91	314.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS1_k127_6167163_16	1499967.BAYZ01000194_gene3126	4.076e-23	102.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS1_k127_6167163_15	1396141.BATP01000016_gene2814	2.065e-27	121.0	COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,2ITKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
CMS1_k127_6172281_2	1499968.TCA2_4709	1.267e-08	61.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HF0T@91061|Bacilli,2750Q@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_6172281_0	1121861.KB899910_gene749	1.244e-66	235.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,2JRRR@204441|Rhodospirillales	204441|Rhodospirillales	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS1_k127_6172281_1	1121116.KB894765_gene738	4.591e-62	223.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VHWQ@28216|Betaproteobacteria,4A9ZX@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS1_k127_6187720_2	583355.Caka_1769	1.967e-56	206.0	COG0307@1|root,COG0307@2|Bacteria,46SU1@74201|Verrucomicrobia,3K7ZH@414999|Opitutae	414999|Opitutae	H	TIGRFAM riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS1_k127_6187720_1	583355.Caka_1053	3.064e-79	272.0	COG1207@1|root,COG1207@2|Bacteria,46U38@74201|Verrucomicrobia,3K7X6@414999|Opitutae	414999|Opitutae	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_6187720_0	583355.Caka_1183	3.592e-105	349.0	COG0533@1|root,COG0533@2|Bacteria,46UIE@74201|Verrucomicrobia,3K75P@414999|Opitutae	414999|Opitutae	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_6214185_9	382464.ABSI01000021_gene375	7.483e-112	375.0	COG0168@1|root,COG0168@2|Bacteria,46UGP@74201|Verrucomicrobia,2IVEG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
CMS1_k127_6214185_3	583355.Caka_2125	4.38e-159	514.0	COG0569@1|root,COG0569@2|Bacteria,46TDR@74201|Verrucomicrobia	74201|Verrucomicrobia	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_6214185_16	382464.ABSI01000012_gene2250	4.753e-53	192.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS1_k127_6214185_17	452637.Oter_0696	3.554e-38	146.0	COG0103@1|root,COG0103@2|Bacteria,46VAQ@74201|Verrucomicrobia,3K7ZU@414999|Opitutae	414999|Opitutae	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS1_k127_6214185_5	583355.Caka_0164	4.742e-131	426.0	COG0002@1|root,COG0002@2|Bacteria,46TRN@74201|Verrucomicrobia,3K8FU@414999|Opitutae	414999|Opitutae	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_6214185_6	382464.ABSI01000012_gene2247	5.746e-126	422.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia,2ITT9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS1_k127_6214185_11	583355.Caka_0162	3.744e-102	341.0	COG0548@1|root,COG0548@2|Bacteria,46SH9@74201|Verrucomicrobia,3K7U8@414999|Opitutae	414999|Opitutae	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS1_k127_6214185_4	794903.OPIT5_17105	2.251e-149	483.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,3K76X@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_6214185_7	794903.OPIT5_09755	1.321e-120	394.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia,3K73T@414999|Opitutae	414999|Opitutae	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_6214185_1	1283300.ATXB01000001_gene941	7.542e-249	789.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XEC0@135618|Methylococcales	135618|Methylococcales	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
CMS1_k127_6214185_2	1506583.JQJY01000001_gene480	3.212e-197	628.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,1HZGP@117743|Flavobacteriia,2NUPT@237|Flavobacterium	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
CMS1_k127_6214185_10	1403819.BATR01000181_gene6063	1.145e-108	357.0	COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia,2ITYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiazole biosynthesis protein ThiG	-	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS1_k127_6214185_14	452637.Oter_3187	1.636e-71	249.0	COG1595@1|root,COG1595@2|Bacteria,46U3X@74201|Verrucomicrobia,3K7M2@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_6214185_15	583355.Caka_1655	1.688e-68	242.0	COG3568@1|root,COG3568@2|Bacteria,46V1K@74201|Verrucomicrobia,3K764@414999|Opitutae	414999|Opitutae	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_6214185_8	583355.Caka_1657	2.758e-118	396.0	COG1502@1|root,COG1502@2|Bacteria,46U00@74201|Verrucomicrobia,3K74W@414999|Opitutae	414999|Opitutae	I	Phospholipase_D-nuclease N-terminal	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS1_k127_6214185_18	583355.Caka_1762	1.182e-19	93.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS1_k127_6214185_13	1209072.ALBT01000035_gene1337	3.788e-76	272.0	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria	1224|Proteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_6214185_12	1209072.ALBT01000035_gene1337	1.853e-86	299.0	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria	1224|Proteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_6214185_0	357808.RoseRS_1213	0.0	1251.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,2G5M1@200795|Chloroflexi,376VN@32061|Chloroflexia	32061|Chloroflexia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_6214185_19	889378.Spiaf_1480	6.473e-18	91.0	COG3884@1|root,COG3884@2|Bacteria,2J7D6@203691|Spirochaetes	203691|Spirochaetes	I	PFAM Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
CMS1_k127_6216233_4	589865.DaAHT2_2094	1.155e-21	100.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MKJ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	synthase	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS1_k127_6216233_1	1282360.ABAC460_00245	0.0	1176.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31,PA14
CMS1_k127_6216233_0	583355.Caka_2178	0.0	1247.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia,3K79K@414999|Opitutae	414999|Opitutae	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_6216233_3	1218084.BBJK01000010_gene1252	2.288e-43	165.0	COG0454@1|root,COG0454@2|Bacteria,1MVVG@1224|Proteobacteria,2VPZT@28216|Betaproteobacteria,1K54D@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_622656_0	452637.Oter_3938	2.564e-122	405.0	COG4591@1|root,COG4591@2|Bacteria,46UC8@74201|Verrucomicrobia,3K7GQ@414999|Opitutae	414999|Opitutae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS1_k127_622656_1	452637.Oter_3937	2.241e-84	286.0	COG1136@1|root,COG1136@2|Bacteria,46UT0@74201|Verrucomicrobia,3K7YN@414999|Opitutae	414999|Opitutae	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS1_k127_622656_2	583355.Caka_1126	2.828e-36	141.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,3K7Y1@414999|Opitutae	414999|Opitutae	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_6251217_5	1300350.DSW25_06295	2.3e-12	71.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5HA@28211|Alphaproteobacteria,3ZVFR@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_6251217_6	631362.Thi970DRAFT_00969	1.281e-11	66.0	2E4KB@1|root,32ZFA@2|Bacteria,1N6R9@1224|Proteobacteria,1SFP8@1236|Gammaproteobacteria,1WZH8@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6251217_3	580332.Slit_1717	2.816e-74	252.0	COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,2W324@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
CMS1_k127_6251217_4	1158756.AQXQ01000012_gene1997	8.939e-49	178.0	2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria,1S4CA@1236|Gammaproteobacteria,1WY9U@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6251217_0	396588.Tgr7_0350	0.0	1191.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_6251217_2	580332.Slit_1714	5.117e-96	316.0	COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria,2W0BB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4
CMS1_k127_6251217_1	1123393.KB891317_gene2439	2.728e-107	354.0	2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,2W0AA@28216|Betaproteobacteria,1KS9S@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_633977_0	1123070.KB899255_gene1360	1.151e-209	665.0	COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,2ITQT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase family M3	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS1_k127_633977_3	398767.Glov_0953	2.085e-82	283.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2WNAV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_633977_2	338966.Ppro_2179	1.059e-103	347.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2WJUJ@28221|Deltaproteobacteria,43W2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
CMS1_k127_633977_1	583355.Caka_1958	3.736e-156	501.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,3K7IA@414999|Opitutae	414999|Opitutae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS1_k127_654380_0	402881.Plav_2733	4.702e-254	789.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,1JNGS@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_654380_1	991905.SL003B_1735	5.018e-76	257.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,4BQ5M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS1_k127_654380_2	909943.HIMB100_00002840	2.524e-63	217.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2U70K@28211|Alphaproteobacteria,4BQ5B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS1_k127_673654_5	1408473.JHXO01000012_gene442	9.83e-82	280.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,2FQ6R@200643|Bacteroidia	976|Bacteroidetes	S	esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS1_k127_673654_8	644282.Deba_2130	2.623e-68	251.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_673654_9	113355.CM001775_gene445	5.07e-66	246.0	COG0438@1|root,COG0438@2|Bacteria,1G2T9@1117|Cyanobacteria	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_673654_10	583355.Caka_1453	2.162e-48	181.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_673654_4	335543.Sfum_2415	3.798e-95	317.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2MQ9V@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_673654_6	335543.Sfum_2414	3.631e-78	275.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,2MQ7Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS1_k127_673654_12	583355.Caka_1263	2.733e-40	157.0	COG0546@1|root,COG0546@2|Bacteria,46VW7@74201|Verrucomicrobia,3K7X3@414999|Opitutae	414999|Opitutae	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_673654_3	573370.DMR_22610	5.237e-118	394.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,2M991@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glutamate-cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS1_k127_673654_2	1232410.KI421415_gene2975	2.491e-169	544.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
CMS1_k127_673654_1	794903.OPIT5_02845	1.43e-180	580.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,3K7F3@414999|Opitutae	414999|Opitutae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_673654_13	583355.Caka_0750	1.782e-30	131.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,3K8IY@414999|Opitutae	414999|Opitutae	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_673654_7	583355.Caka_1625	1.199e-68	251.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia,3K81X@414999|Opitutae	414999|Opitutae	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
CMS1_k127_673654_14	1209989.TepiRe1_0539	1.421e-23	109.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,42GXN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0079, ATPase	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS1_k127_673654_11	583355.Caka_1730	4.291e-48	178.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03207,ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_673654_0	382464.ABSI01000010_gene3290	0.0	1234.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,2ITPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS1_k127_673706_7	935567.JAES01000009_gene1708	1.528e-07	55.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,1RYWI@1236|Gammaproteobacteria,1X3AM@135614|Xanthomonadales	135614|Xanthomonadales	GM	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	wzm	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS1_k127_673706_1	583355.Caka_1532	8.708e-161	514.0	COG1158@1|root,COG1158@2|Bacteria,46TIH@74201|Verrucomicrobia,3K753@414999|Opitutae	414999|Opitutae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
CMS1_k127_673706_5	278957.ABEA03000041_gene2248	4.068e-29	121.0	COG0184@1|root,COG0184@2|Bacteria,46T87@74201|Verrucomicrobia,3K894@414999|Opitutae	414999|Opitutae	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS1_k127_673706_0	583355.Caka_2669	3.875e-304	955.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia,3K7BU@414999|Opitutae	414999|Opitutae	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS1_k127_673706_2	1191523.MROS_0341	3.088e-148	481.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS1_k127_673706_4	472759.Nhal_0692	4.456e-46	171.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1WW3I@135613|Chromatiales	135613|Chromatiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
CMS1_k127_673706_3	278957.ABEA03000032_gene2687	1.367e-51	194.0	2F1X5@1|root,33UWR@2|Bacteria,46V3H@74201|Verrucomicrobia,3K750@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_673706_6	518766.Rmar_0191	5.131e-21	94.0	COG0537@1|root,COG0537@2|Bacteria,4NXJE@976|Bacteroidetes,1FJE7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS1_k127_693044_0	660470.Theba_1169	5.266e-159	508.0	COG1089@1|root,COG1089@2|Bacteria,2GCQB@200918|Thermotogae	200918|Thermotogae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_693044_4	1472716.KBK24_0127670	3.747e-63	223.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,2VVVZ@28216|Betaproteobacteria,1K3EF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	ko:K13006,ko:K19429	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
CMS1_k127_693044_2	880073.Calab_2246	6.997e-119	394.0	COG0399@1|root,COG0399@2|Bacteria,2NQIB@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	pglE	-	2.6.1.102,2.6.1.34	ko:K13010,ko:K15910,ko:K19430	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_693044_3	1121459.AQXE01000005_gene1516	1.521e-75	258.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WN9A@28221|Deltaproteobacteria,2MG2V@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
CMS1_k127_693044_7	404380.Gbem_0575	7.668e-14	78.0	COG2259@1|root,COG2259@2|Bacteria,1NC5I@1224|Proteobacteria,42V27@68525|delta/epsilon subdivisions,2WS2G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Methylamine	-	-	-	-	-	-	-	-	-	-	-	-	MauE
CMS1_k127_693044_8	583355.Caka_2217	3.925e-07	58.0	COG0607@1|root,COG0607@2|Bacteria,46WVZ@74201|Verrucomicrobia,3K8HQ@414999|Opitutae	414999|Opitutae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_693044_1	497964.CfE428DRAFT_4013	2.44e-140	458.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS1_k127_693044_6	926562.Oweho_0926	4.367e-35	138.0	COG2199@1|root,COG3706@2|Bacteria,4PMSX@976|Bacteroidetes	976|Bacteroidetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_693044_5	926562.Oweho_1605	8.26e-52	197.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_4,PAS_9
CMS1_k127_702147_2	1894.JOER01000005_gene2604	1.081e-27	125.0	COG3555@1|root,COG3555@2|Bacteria,2ICJH@201174|Actinobacteria	201174|Actinobacteria	O	Aspartyl Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
CMS1_k127_702147_0	318586.Pden_4198	2.462e-148	492.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,2TV1I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_702147_1	1297865.APJD01000001_gene5880	2.5e-127	431.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,3JR7Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	symbiont process	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS1_k127_710931_0	583355.Caka_2353	2.231e-233	767.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia,3K7E6@414999|Opitutae	414999|Opitutae	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS1_k127_710931_4	1232410.KI421422_gene1961	2.223e-09	60.0	COG4710@1|root,COG4710@2|Bacteria,1PWUN@1224|Proteobacteria,432CR@68525|delta/epsilon subdivisions,2WX5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TraY domain	-	-	-	-	-	-	-	-	-	-	-	-	TraY
CMS1_k127_710931_3	1168065.DOK_02076	4.166e-27	112.0	COG2026@1|root,COG2026@2|Bacteria,1N76D@1224|Proteobacteria,1SCNM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DJ	TIGRFAM Addiction module toxin, RelE StbE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CMS1_k127_710931_2	65393.PCC7424_3406	1.005e-28	123.0	2B7JP@1|root,320QE@2|Bacteria,1GAE5@1117|Cyanobacteria,3KJPZ@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF4145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4145
CMS1_k127_710931_1	583355.Caka_2248	6.908e-214	674.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,3K77X@414999|Opitutae	414999|Opitutae	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS1_k127_72247_4	794903.OPIT5_17985	1.567e-51	188.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia,3K736@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_72247_0	452637.Oter_3137	1.648e-119	394.0	COG1077@1|root,COG1077@2|Bacteria,46TXV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_72247_3	1157490.EL26_16780	8.938e-54	198.0	COG0500@1|root,COG2226@2|Bacteria,1TT25@1239|Firmicutes,4HD6C@91061|Bacilli	91061|Bacilli	Q	Methyltransferase	ubiE	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS1_k127_72247_1	497964.CfE428DRAFT_1406	2.183e-119	404.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM CBS domain containing protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS1_k127_72247_5	1122172.KB890259_gene807	2.63e-09	64.0	COG1762@1|root,COG1762@2|Bacteria,379WR@32066|Fusobacteria	32066|Fusobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
CMS1_k127_72247_2	243231.GSU2189	9.373e-59	218.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,43SHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
CMS1_k127_754482_1	452637.Oter_2116	3.009e-107	356.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_754482_2	583355.Caka_2116	1.158e-98	332.0	COG0157@1|root,COG0157@2|Bacteria,46UE1@74201|Verrucomicrobia,3K7T8@414999|Opitutae	414999|Opitutae	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS1_k127_754482_3	452637.Oter_0086	9.85e-91	310.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,46UKU@74201|Verrucomicrobia,3K7K5@414999|Opitutae	414999|Opitutae	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS1_k127_754482_0	452637.Oter_2978	1.963e-204	661.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_8,DLH,Esterase_phd,PA14,fn3
CMS1_k127_754482_4	1095769.CAHF01000025_gene765	0.0002304	51.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4738N@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
CMS1_k127_762590_5	279714.FuraDRAFT_0811	3.13e-63	225.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,2KPGH@206351|Neisseriales	206351|Neisseriales	M	Efflux transporter, outer membrane factor lipoprotein, NodT family	oprM	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_762590_0	795666.MW7_0022	0.0	1176.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K25W@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS1_k127_762590_2	279714.FuraDRAFT_0809	3.7e-111	372.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,2KPHI@206351|Neisseriales	206351|Neisseriales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS1_k127_762590_3	278957.ABEA03000004_gene4531	2.255e-89	304.0	COG0583@1|root,COG0583@2|Bacteria,46TTX@74201|Verrucomicrobia,3K88B@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_762590_1	1123393.KB891326_gene229	4.394e-134	434.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VJ7N@28216|Betaproteobacteria,1KRT6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS1_k127_762590_4	1121094.KB894645_gene202	5.923e-67	243.0	COG2755@1|root,COG2755@2|Bacteria,4NFVN@976|Bacteroidetes,2FXHF@200643|Bacteroidia,4AWD7@815|Bacteroidaceae	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_789706_6	382464.ABSI01000002_gene4387	4.847e-133	430.0	COG1116@1|root,COG1116@2|Bacteria,46TJD@74201|Verrucomicrobia,2ITUG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_789706_13	583355.Caka_2073	1.477e-109	368.0	COG1402@1|root,COG1402@2|Bacteria,46UG3@74201|Verrucomicrobia,3K9D5@414999|Opitutae	414999|Opitutae	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_789706_1	583355.Caka_2072	1.369e-252	784.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,3K9DB@414999|Opitutae	414999|Opitutae	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
CMS1_k127_789706_23	1504823.CCMM01000013_gene2472	1.888e-25	120.0	COG0438@1|root,COG0438@2|Bacteria,2NQ20@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	wbjE	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_789706_21	1121936.AUHI01000002_gene2620	9.35e-60	213.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HHDH@91061|Bacilli	91061|Bacilli	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	epsE2	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CMS1_k127_789706_20	1444306.JFZC01000047_gene344	1.037e-65	237.0	2A3F8@1|root,30RXY@2|Bacteria,1V59N@1239|Firmicutes,4HIES@91061|Bacilli	91061|Bacilli	S	Shikimate / quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
CMS1_k127_789706_18	1121438.JNJA01000009_gene4168	7.983e-86	297.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42PBK@68525|delta/epsilon subdivisions,2WIZX@28221|Deltaproteobacteria,2M99E@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CMS1_k127_789706_7	497964.CfE428DRAFT_2871	1.395e-121	406.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	astD	GO:0003674,GO:0003824,GO:0004029,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c20030,iEcHS_1320.EcHS_A1829,ic_1306.c2146	Aldedh
CMS1_k127_789706_8	497964.CfE428DRAFT_2872	2.279e-121	397.0	COG0123@1|root,COG0123@2|Bacteria,46T7E@74201|Verrucomicrobia	74201|Verrucomicrobia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_789706_5	497964.CfE428DRAFT_0657	5.621e-146	471.0	COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Alanine dehydrogenase/PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_789706_9	1279015.KB908460_gene2867	1.896e-118	395.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1Y586@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_789706_22	382464.ABSI01000013_gene1583	2.18e-45	177.0	COG1609@1|root,COG1609@2|Bacteria,46TVE@74201|Verrucomicrobia,2IVYJ@203494|Verrucomicrobiae	74201|Verrucomicrobia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI
CMS1_k127_789706_15	641491.DND132_1033	3.109e-98	332.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MUK@68525|delta/epsilon subdivisions,2X5CN@28221|Deltaproteobacteria,2M9KP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS1_k127_789706_10	879212.DespoDRAFT_01752	1.537e-116	382.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,42PMI@68525|delta/epsilon subdivisions,2WM2W@28221|Deltaproteobacteria,2MPQT@213118|Desulfobacterales	28221|Deltaproteobacteria	U	spermidine putrescine transport system, permease	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_789706_16	526227.Mesil_2403	5.62e-95	317.0	COG1177@1|root,COG1177@2|Bacteria,1WICS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_789706_11	1122222.AXWR01000002_gene2141	7.994e-114	378.0	COG0687@1|root,COG0687@2|Bacteria,1WIRI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CMS1_k127_789706_3	583355.Caka_1258	2.828e-226	709.0	COG2308@1|root,COG2308@2|Bacteria,46TR2@74201|Verrucomicrobia,3K7Q4@414999|Opitutae	414999|Opitutae	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
CMS1_k127_789706_14	382464.ABSI01000011_gene2677	4.956e-106	355.0	COG2307@1|root,COG2307@2|Bacteria,46S7Q@74201|Verrucomicrobia,2IU62@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CMS1_k127_789706_0	62928.azo1604	0.0	1450.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KV93@206389|Rhodocyclales	206389|Rhodocyclales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
CMS1_k127_789706_4	1210884.HG799466_gene12806	8.549e-185	607.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,2IXTY@203682|Planctomycetes	203682|Planctomycetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
CMS1_k127_789706_19	1430440.MGMSRv2_0171	1.641e-78	271.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2TRFC@28211|Alphaproteobacteria,2JQTP@204441|Rhodospirillales	204441|Rhodospirillales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
CMS1_k127_789706_2	452637.Oter_3237	1.63e-239	749.0	COG3507@1|root,COG3507@2|Bacteria,46TKI@74201|Verrucomicrobia,3KA3C@414999|Opitutae	2|Bacteria	G	PFAM glycoside hydrolase family 62	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,Glyco_hydro_43
CMS1_k127_789706_12	452637.Oter_2047	6.925e-111	371.0	COG3867@1|root,COG3867@2|Bacteria,46VSS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycosyl hydrolase 53 domain protein	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
CMS1_k127_789706_17	452637.Oter_2048	5.086e-89	300.0	COG4774@1|root,COG4774@2|Bacteria	452637.Oter_2048|-	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_790097_3	497964.CfE428DRAFT_3459	2.267e-56	207.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
CMS1_k127_790097_2	583355.Caka_0777	2.392e-88	301.0	COG1721@1|root,COG1721@2|Bacteria,46SPD@74201|Verrucomicrobia,3K81Q@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_790097_0	583355.Caka_0776	2.776e-136	442.0	COG0714@1|root,COG0714@2|Bacteria,46SC8@74201|Verrucomicrobia,3K7W0@414999|Opitutae	414999|Opitutae	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_790097_4	1027273.GZ77_24110	1.326e-14	84.0	2DB7S@1|root,2Z7NB@2|Bacteria,1R5PS@1224|Proteobacteria,1RXZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	lipopolysaccharide core region biosynthetic process	rfaZ	GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12981	ko00540,map00540	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT73	-	-
CMS1_k127_790097_1	246200.SPOA0345	1.184e-99	334.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,4NBCQ@97050|Ruegeria	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_793789_0	382464.ABSI01000011_gene3005	1.333e-114	377.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia,2ITTU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	AIR synthase related protein, N-terminal domain	-	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_793789_2	278957.ABEA03000117_gene1111	9.155e-17	89.0	COG2976@1|root,COG2976@2|Bacteria,46WP7@74201|Verrucomicrobia,3K88D@414999|Opitutae	414999|Opitutae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
CMS1_k127_793789_1	382464.ABSI01000002_gene4257	9.392e-18	83.0	COG0326@1|root,COG0326@2|Bacteria,46U76@74201|Verrucomicrobia,2IU3I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
CMS1_k127_811608_0	401053.AciPR4_4148	7.834e-173	548.0	COG3613@1|root,COG3613@2|Bacteria	2|Bacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4406
CMS1_k127_811608_1	1231190.NA8A_05578	1.019e-54	208.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2U05W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
CMS1_k127_816042_1	644282.Deba_2721	1.148e-77	279.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2WM8F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Chemotaxis sensory transducer	mcp64H-1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4,dCache_1
CMS1_k127_816042_2	278957.ABEA03000120_gene1237	2.458e-37	144.0	COG2967@1|root,COG2967@2|Bacteria,46T44@74201|Verrucomicrobia,3K84K@414999|Opitutae	414999|Opitutae	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS1_k127_816042_0	1403819.BATR01000096_gene3092	1.294e-179	581.0	COG0475@1|root,COG0475@2|Bacteria,46U4K@74201|Verrucomicrobia,2IV1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
CMS1_k127_828041_2	583355.Caka_1902	4.68e-101	336.0	COG0623@1|root,COG0623@2|Bacteria,46TU1@74201|Verrucomicrobia,3K780@414999|Opitutae	414999|Opitutae	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_828041_8	338966.Ppro_3332	3.136e-49	189.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
CMS1_k127_828041_10	583355.Caka_2055	2.92e-33	138.0	COG0576@1|root,COG0576@2|Bacteria,46VZ0@74201|Verrucomicrobia,3K81S@414999|Opitutae	414999|Opitutae	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_828041_0	583355.Caka_2056	2.927e-161	516.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,3K72Q@414999|Opitutae	414999|Opitutae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_828041_6	583355.Caka_2481	6.317e-65	231.0	COG0566@1|root,COG0566@2|Bacteria,46TF9@74201|Verrucomicrobia,3K7VA@414999|Opitutae	414999|Opitutae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_828041_5	583355.Caka_2954	2.695e-91	311.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia,3K7TG@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS1_k127_828041_1	794903.OPIT5_28335	1.357e-121	405.0	COG1109@1|root,COG1109@2|Bacteria,46SJ2@74201|Verrucomicrobia,3K7CB@414999|Opitutae	414999|Opitutae	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_828041_12	485913.Krac_12282	4.27e-08	66.0	2CHUW@1|root,2ZECY@2|Bacteria,2G9K0@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_828041_4	1121403.AUCV01000046_gene1117	2.389e-94	319.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,42Z8V@68525|delta/epsilon subdivisions,2WUJD@28221|Deltaproteobacteria,2MMN7@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS1_k127_828041_3	794903.OPIT5_08600	5.018e-97	339.0	COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
CMS1_k127_828041_7	69042.WH5701_08094	2.427e-55	209.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_828041_9	1403819.BATR01000092_gene2752	1.775e-41	160.0	COG0569@1|root,COG0569@2|Bacteria,46W0A@74201|Verrucomicrobia,2IUXU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_828041_11	349741.Amuc_0041	2.709e-08	57.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,2ITHW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_843521_0	382464.ABSI01000010_gene3770	4.514e-145	468.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,2ITNP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_843521_1	382464.ABSI01000005_gene1243	1.61e-134	448.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,2ITUJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
CMS1_k127_855655_6	1304883.KI912532_gene901	2.093e-31	127.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2VHZ6@28216|Betaproteobacteria,2KV85@206389|Rhodocyclales	206389|Rhodocyclales	E	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_855655_2	382464.ABSI01000006_gene911	2.67e-122	405.0	COG4124@1|root,COG4124@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM27,CBM_11,Glyco_hydro_26
CMS1_k127_855655_0	382464.ABSI01000007_gene4070	6.403e-165	523.0	COG2152@1|root,COG2152@2|Bacteria,46S8T@74201|Verrucomicrobia,2IUQX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
CMS1_k127_855655_1	452637.Oter_2315	4.3e-142	467.0	COG2211@1|root,COG2211@2|Bacteria,46UFW@74201|Verrucomicrobia	74201|Verrucomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS1_k127_855655_3	583355.Caka_0677	5.134e-102	346.0	COG1167@1|root,COG1167@2|Bacteria,46TGY@74201|Verrucomicrobia,3K7IS@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_855655_5	583355.Caka_0239	5.72e-65	230.0	COG1321@1|root,COG1321@2|Bacteria,46T7C@74201|Verrucomicrobia,3K8J0@414999|Opitutae	414999|Opitutae	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_855655_7	583355.Caka_2567	1.197e-28	119.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_855655_4	382464.ABSI01000013_gene1691	9.108e-70	252.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46VEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
CMS1_k127_855655_8	363253.LI0013	8.757e-24	102.0	COG0204@1|root,COG0204@2|Bacteria,1PY44@1224|Proteobacteria,42NR4@68525|delta/epsilon subdivisions,2WKKQ@28221|Deltaproteobacteria,2MAGC@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_862240_1	1247649.D560_2102	6.752e-49	190.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VKED@28216|Betaproteobacteria,3T6UW@506|Alcaligenaceae	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_862240_0	1122604.JONR01000029_gene3380	1.508e-311	984.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X41A@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18303	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.17	-	-	ACR_tran
CMS1_k127_862240_2	557598.LHK_01426	4.721e-05	48.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,2KPHI@206351|Neisseriales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS1_k127_869820_1	941449.dsx2_2986	4.061e-31	129.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,42NMN@68525|delta/epsilon subdivisions,2WJJH@28221|Deltaproteobacteria,2MBJ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	TIGRFAM Phage shock protein A	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS1_k127_869820_2	1307759.JOMJ01000003_gene2224	3.154e-24	106.0	COG1983@1|root,COG1983@2|Bacteria,1PWDN@1224|Proteobacteria,42TA8@68525|delta/epsilon subdivisions,2WPVU@28221|Deltaproteobacteria,2MCNH@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PspC domain protein	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CMS1_k127_869820_3	911239.CF149_05639	3.394e-13	82.0	COG1538@1|root,COG1538@2|Bacteria,1MWQK@1224|Proteobacteria,1RSGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_869820_0	382464.ABSI01000005_gene1146	1.972e-45	173.0	COG0845@1|root,COG0845@2|Bacteria,46U5P@74201|Verrucomicrobia,2IU9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS1_k127_884635_1	1403819.BATR01000124_gene4370	8.061e-42	157.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS1_k127_884635_0	1195236.CTER_4522	3.853e-233	734.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS1_k127_940404_1	452637.Oter_0897	5.183e-127	428.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,3K7S6@414999|Opitutae	414999|Opitutae	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS1_k127_940404_5	596153.Alide_2291	4.989e-71	243.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,2VQ0D@28216|Betaproteobacteria,4ADFN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
CMS1_k127_940404_8	452637.Oter_3317	2.843e-15	82.0	COG2730@1|root,COG2730@2|Bacteria,46XJ7@74201|Verrucomicrobia,3K99G@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CMS1_k127_940404_0	452637.Oter_3317	3.031e-142	462.0	COG2730@1|root,COG2730@2|Bacteria,46XJ7@74201|Verrucomicrobia,3K99G@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CMS1_k127_940404_6	865937.Gilli_2538	2.145e-42	169.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,1HY47@117743|Flavobacteriia,2P7G3@244698|Gillisia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS1_k127_940404_3	1166018.FAES_1266	6.964e-82	279.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS1_k127_940404_9	794903.OPIT5_09990	1.11e-13	74.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia,3K8CC@414999|Opitutae	414999|Opitutae	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS1_k127_940404_2	452637.Oter_3022	3.573e-120	395.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,46U8V@74201|Verrucomicrobia,3K7U6@414999|Opitutae	414999|Opitutae	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS1_k127_940404_7	452637.Oter_0896	8.781e-21	103.0	2ARR8@1|root,30Z2V@2|Bacteria,46W2A@74201|Verrucomicrobia,3K8D5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_940404_4	382464.ABSI01000011_gene2861	1.774e-74	266.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_957712_1	196490.AUEZ01000042_gene7229	3.908e-67	236.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JUB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_957712_0	926569.ANT_05700	2.01e-69	240.0	COG2080@1|root,COG2080@2|Bacteria,2G8E9@200795|Chloroflexi	200795|Chloroflexi	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_957712_2	459349.CLOAM1593	5.726e-63	221.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.84,6.3.5.6,6.3.5.7	ko:K02433,ko:K19837	ko00791,ko00970,ko01100,ko01120,map00791,map00970,map01100,map01120	-	R03905,R04212,R05563	RC00010,RC01287	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
## 2365 queries scanned
## Total time (seconds): 42.486299991607666
## Rate: 55.67 q/s