## Fri Nov  8 06:55:14 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS1_bin.88.fa -m mmseqs --itype genome -o CMS1_bin.88 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS1_bin.88 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS1_k127_1008244_1	1288298.rosmuc_03386	5.015e-189	594.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,46QCG@74030|Roseovarius	28211|Alphaproteobacteria	GM	nucleoside-diphosphate sugar epimerases	lpsB2	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CMS1_k127_1008244_0	1354722.JQLS01000008_gene1014	1.517e-240	751.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,2TSMY@28211|Alphaproteobacteria,46P8M@74030|Roseovarius	28211|Alphaproteobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	cxp	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
CMS1_k127_1008244_2	1354722.JQLS01000008_gene1013	4.109e-79	266.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,46PTU@74030|Roseovarius	28211|Alphaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS1_k127_1008700_0	314264.ROS217_10382	0.0	1325.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,46PVT@74030|Roseovarius	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
CMS1_k127_1008700_4	1354722.JQLS01000008_gene3250	2.494e-112	365.0	COG2740@1|root,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,2U9RY@28211|Alphaproteobacteria,46PGV@74030|Roseovarius	28211|Alphaproteobacteria	K	nucleic-acid-binding protein implicated in transcription termination	MA20_23920	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448,Ribosomal_L7Ae
CMS1_k127_1008700_1	1354722.JQLS01000008_gene3251	9.389e-312	960.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,46PTJ@74030|Roseovarius	28211|Alphaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS1_k127_1008700_5	1354722.JQLS01000008_gene3252	2.582e-99	332.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,46PCY@74030|Roseovarius	28211|Alphaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS1_k127_1008700_3	1123247.AUIJ01000003_gene1997	2.068e-155	497.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	peptidase	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
CMS1_k127_1008700_2	391613.RTM1035_19426	1.024e-243	766.0	COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,2TUN2@28211|Alphaproteobacteria,46P22@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0006 Xaa-Pro aminopeptidase	pepQ	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_1023085_1	1354722.JQLS01000008_gene1216	2.519e-119	386.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,46PDT@74030|Roseovarius	28211|Alphaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_1023085_0	1354722.JQLS01000008_gene2001	1.173e-183	582.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,46NQX@74030|Roseovarius	28211|Alphaproteobacteria	H	Molybdenum cofactor biosynthesis protein A	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_1023085_2	1354722.JQLS01000008_gene2000	4.664e-84	281.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,46PBG@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS1_k127_1023085_3	1288298.rosmuc_01126	4.786e-34	132.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,46Q0U@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS1_k127_103290_3	1288298.rosmuc_03092	1.437e-12	67.0	2BV99@1|root,32QP2@2|Bacteria,1Q4RN@1224|Proteobacteria,2VB6T@28211|Alphaproteobacteria,46R4F@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_103290_2	314264.ROS217_17040	1.13e-26	111.0	2A7C1@1|root,30W8X@2|Bacteria,1Q4S5@1224|Proteobacteria,2VB78@28211|Alphaproteobacteria,46R5J@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1127
CMS1_k127_103290_0	1354722.JQLS01000008_gene595	9.478e-282	869.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2TRPX@28211|Alphaproteobacteria,46NDK@74030|Roseovarius	28211|Alphaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_103290_1	314264.ROS217_17050	2.787e-262	817.0	COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,2TTH5@28211|Alphaproteobacteria,46QE2@74030|Roseovarius	28211|Alphaproteobacteria	EH	Acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB_1	-	2.2.1.6,4.1.1.75	ko:K01652,ko:K12253	ko00290,ko00330,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00330,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R03178,R04672,R04673,R08648	RC00027,RC00106,RC00506,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_103290_4	1457393.AZ09_00340	9.853e-07	51.0	COG0583@1|root,COG0583@2|Bacteria,1N4P5@1224|Proteobacteria,2U6KC@28211|Alphaproteobacteria,2JZHP@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_103564_1	89187.ISM_08680	1.503e-126	410.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,2TSTR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS1_k127_103564_0	314264.ROS217_10342	7.714e-220	684.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,46PDQ@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS1_k127_1049053_3	391613.RTM1035_18470	1.105e-28	115.0	COG0225@1|root,COG0225@2|Bacteria,1R5GQ@1224|Proteobacteria,2VGNN@28211|Alphaproteobacteria,46NBC@74030|Roseovarius	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_2	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_1049053_2	1354722.JQLS01000008_gene3495	9.17e-104	346.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,2TSUM@28211|Alphaproteobacteria,46P6X@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_1049053_0	89187.ISM_06675	0.0	1344.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,46PPC@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0281 Malic enzyme	tme	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_1049053_1	391613.RTM1035_18480	6.004e-137	439.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,46PGN@74030|Roseovarius	28211|Alphaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_1054329_7	391593.RCCS2_12649	2.579e-20	91.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2TQMU@28211|Alphaproteobacteria,2P2C6@2433|Roseobacter	28211|Alphaproteobacteria	H	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
CMS1_k127_1054329_4	314256.OG2516_01069	1.703e-66	234.0	COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,2TRVW@28211|Alphaproteobacteria,2PE6E@252301|Oceanicola	28211|Alphaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
CMS1_k127_1054329_3	1342299.Z947_2243	8.133e-78	263.0	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2TVBW@28211|Alphaproteobacteria,3ZXMP@60136|Sulfitobacter	28211|Alphaproteobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
CMS1_k127_1054329_0	1443111.JASG01000004_gene2369	0.0	1075.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2TSXP@28211|Alphaproteobacteria,3ZW62@60136|Sulfitobacter	28211|Alphaproteobacteria	E	in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
CMS1_k127_1054329_6	314256.OG2516_01054	2.714e-53	188.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2U9T4@28211|Alphaproteobacteria,2PED3@252301|Oceanicola	28211|Alphaproteobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
CMS1_k127_1054329_5	1443111.JASG01000004_gene2372	2.33e-57	199.0	COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,2U947@28211|Alphaproteobacteria,3ZXMA@60136|Sulfitobacter	28211|Alphaproteobacteria	E	UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
CMS1_k127_1054329_2	1342299.Z947_2248	2.5e-99	331.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2U57R@28211|Alphaproteobacteria,3ZX29@60136|Sulfitobacter	28211|Alphaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
CMS1_k127_1054329_1	1342299.Z947_2250	1.467e-250	778.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2TS3I@28211|Alphaproteobacteria,3ZW2P@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
CMS1_k127_1058256_1	1116375.VEJY3_06585	3.497e-80	272.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,1SBT6@1236|Gammaproteobacteria,1Y11R@135623|Vibrionales	135623|Vibrionales	E	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
CMS1_k127_1058256_0	1354722.JQLS01000008_gene1937	6.849e-168	531.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2TU5X@28211|Alphaproteobacteria,46QGC@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS1_k127_1075812_3	1288298.rosmuc_02293	9.355e-90	297.0	COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,2U2FN@28211|Alphaproteobacteria,46Q17@74030|Roseovarius	28211|Alphaproteobacteria	T	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
CMS1_k127_1075812_0	1288298.rosmuc_02294	4.669e-228	709.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,2TSHW@28211|Alphaproteobacteria,46NAI@74030|Roseovarius	28211|Alphaproteobacteria	I	Fatty acid desaturase	alkB2	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
CMS1_k127_1075812_1	1354722.JQLS01000008_gene266	1.791e-179	566.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria,46PBP@74030|Roseovarius	28211|Alphaproteobacteria	L	COG1194 A G-specific DNA glycosylase	mutY	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS1_k127_1075812_4	1354722.JQLS01000008_gene267	5.157e-76	258.0	COG5389@1|root,COG5389@2|Bacteria,1N82D@1224|Proteobacteria,2UFA9@28211|Alphaproteobacteria,46NXT@74030|Roseovarius	28211|Alphaproteobacteria	S	COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives	MA20_42435	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS1_k127_1075812_2	314264.ROS217_13166	5.954e-99	328.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,46P3N@74030|Roseovarius	28211|Alphaproteobacteria	O	Thiol disulfide interchange protein, DsbA family	MA20_42440	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS1_k127_1078459_1	1354722.JQLS01000008_gene2062	1.665e-158	502.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,46PE6@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS1_k127_1078459_0	89187.ISM_10790	2.63e-278	863.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,46NT3@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS1_k127_1092820_6	439497.RR11_3484	3.428e-51	182.0	2CCMQ@1|root,32RW3@2|Bacteria,1MZHB@1224|Proteobacteria,2UCC9@28211|Alphaproteobacteria,4NC7H@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2794)	MA20_43795	-	-	-	-	-	-	-	-	-	-	-	DUF2794
CMS1_k127_1092820_7	314264.ROS217_12631	1.148e-40	154.0	COG2005@1|root,COG2005@2|Bacteria,1P9SX@1224|Proteobacteria,2UC9Q@28211|Alphaproteobacteria,46R67@74030|Roseovarius	28211|Alphaproteobacteria	S	Bacterial regulatory helix-turn-helix protein, lysR family	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
CMS1_k127_1092820_5	1123247.AUIJ01000001_gene1778	2.157e-73	256.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS1_k127_1092820_4	1123247.AUIJ01000001_gene1779	1.11e-103	341.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type molybdate transport system, permease component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS1_k127_1092820_2	1123247.AUIJ01000001_gene1780	7.414e-127	419.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
CMS1_k127_1092820_1	1354722.JQLS01000008_gene3012	3.238e-200	625.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TQSZ@28211|Alphaproteobacteria,46Q7G@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family	speB-4	-	3.5.3.11,3.5.3.17	ko:K01480,ko:K18459	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS1_k127_1092820_3	314264.ROS217_11386	3.749e-122	395.0	COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,46Q55@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
CMS1_k127_1092820_0	391613.RTM1035_16857	2.215e-204	639.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,46NQY@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the peptidase M17 family	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
CMS1_k127_1096992_1	314264.ROS217_23077	4.498e-85	284.0	COG1802@1|root,COG1802@2|Bacteria,1P945@1224|Proteobacteria,2TV2V@28211|Alphaproteobacteria,46R1X@74030|Roseovarius	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_1096992_0	388739.RSK20926_06367	5.32e-117	388.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2TS7I@28211|Alphaproteobacteria,2P1MP@2433|Roseobacter	28211|Alphaproteobacteria	K	COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K21826	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
CMS1_k127_111197_8	644107.SL1157_0527	1.039e-120	402.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2TVIP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HATPase_c,HisKA
CMS1_k127_111197_12	999550.KI421507_gene623	4.003e-51	188.0	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,2UE0N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
CMS1_k127_111197_5	1354722.JQLS01000008_gene964	2.942e-160	518.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2U48I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Haem_oxygenas_2
CMS1_k127_111197_9	1354722.JQLS01000008_gene965	4.541e-106	349.0	COG0300@1|root,COG0300@2|Bacteria,1NT7C@1224|Proteobacteria,2U0P1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_111197_6	1354722.JQLS01000008_gene966	2.632e-134	433.0	COG2175@1|root,COG2175@2|Bacteria,1MWQ6@1224|Proteobacteria,2TQX1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS1_k127_111197_10	1379270.AUXF01000004_gene3183	2.788e-101	341.0	COG1231@1|root,COG1231@2|Bacteria	2|Bacteria	E	oxidoreductase activity	sdr2	-	1.4.3.10,1.4.3.4	ko:K00274,ko:K03343	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R01151,R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_111197_1	89187.ISM_11915	0.0	1068.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,46Q1U@74030|Roseovarius	28211|Alphaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
CMS1_k127_111197_2	391613.RTM1035_14582	1.069e-238	741.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2TU4M@28211|Alphaproteobacteria,46PC8@74030|Roseovarius	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_111197_3	1288298.rosmuc_02442	7.767e-193	609.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TSKV@28211|Alphaproteobacteria,46PUC@74030|Roseovarius	28211|Alphaproteobacteria	C	related to aryl-alcohol dehydrogenases	tas	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_111197_4	1288298.rosmuc_02569	2.183e-161	512.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,46P40@74030|Roseovarius	28211|Alphaproteobacteria	G	and related enzymes of inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_111197_11	1354722.JQLS01000008_gene499	8.896e-69	235.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2UBRG@28211|Alphaproteobacteria,46QYI@74030|Roseovarius	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_111197_7	314264.ROS217_04000	2.858e-122	398.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,46Q0K@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_111197_0	1354722.JQLS01000008_gene501	0.0	1885.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,46PB5@74030|Roseovarius	28211|Alphaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
CMS1_k127_111197_13	1288298.rosmuc_02574	5.824e-50	179.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2U7B2@28211|Alphaproteobacteria,46PRI@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1522 Transcriptional regulators	putR	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS1_k127_1127333_2	1188256.BASI01000001_gene277	1.483e-20	91.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,3FE7T@34008|Rhodovulum	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	sdpR	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS1_k127_1127333_0	314264.ROS217_08444	2.099e-140	454.0	COG4421@1|root,COG4421@2|Bacteria,1R5RK@1224|Proteobacteria,2U181@28211|Alphaproteobacteria,46RST@74030|Roseovarius	28211|Alphaproteobacteria	G	COG4421 Capsular polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,Methyltransf_21
CMS1_k127_1127333_1	314264.ROS217_08449	5.414e-107	349.0	COG0697@1|root,COG0697@2|Bacteria,1P3V0@1224|Proteobacteria,2TQJK@28211|Alphaproteobacteria,46Q77@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1155017_5	633131.TR2A62_3456	2.387e-75	257.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2U5JQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	decarboxylase	MA20_20490	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
CMS1_k127_1155017_0	391613.RTM1035_13638	3.947e-226	706.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TUMK@28211|Alphaproteobacteria,46QH6@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_1155017_2	1288298.rosmuc_01929	5.295e-126	409.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,2TT08@28211|Alphaproteobacteria,46QAT@74030|Roseovarius	28211|Alphaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
CMS1_k127_1155017_1	391613.RTM1035_13648	2.146e-204	642.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TTU3@28211|Alphaproteobacteria,46QMH@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	aruH	-	2.6.1.1,2.6.1.84	ko:K00812,ko:K12252	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08197	RC00006,RC00008	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_1155017_4	391613.RTM1035_13653	1.996e-90	302.0	COG1309@1|root,COG1309@2|Bacteria,1RJWB@1224|Proteobacteria,2TXDJ@28211|Alphaproteobacteria,46NEM@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS1_k127_1155017_3	391613.RTM1035_13658	2.161e-108	355.0	COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,2TVZC@28211|Alphaproteobacteria,46P3G@74030|Roseovarius	28211|Alphaproteobacteria	E	ABC transporter, ATP-binding protein	aotP	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
CMS1_k127_115834_2	1354722.JQLS01000008_gene3576	3.046e-125	404.0	COG0819@1|root,COG0819@2|Bacteria,1R21S@1224|Proteobacteria,2U0I7@28211|Alphaproteobacteria,46PQV@74030|Roseovarius	28211|Alphaproteobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
CMS1_k127_115834_0	1354722.JQLS01000008_gene3575	1.651e-179	564.0	COG0715@1|root,COG0715@2|Bacteria,1MVRA@1224|Proteobacteria,2TQPE@28211|Alphaproteobacteria,46QHI@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	thi5	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
CMS1_k127_115834_1	391613.RTM1035_19276	3.643e-148	476.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria,46Q9S@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	-	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_115834_3	1469613.JT55_18785	9.42e-82	274.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2U6B1@28211|Alphaproteobacteria,3FDI7@34008|Rhodovulum	28211|Alphaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_1162234_2	1288298.rosmuc_03581	1.488e-37	141.0	COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2TRYK@28211|Alphaproteobacteria,46NYF@74030|Roseovarius	28211|Alphaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF1	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_1162234_1	314264.ROS217_18712	1.867e-87	293.0	COG5342@1|root,COG5342@2|Bacteria,1NA8M@1224|Proteobacteria,2TSY3@28211|Alphaproteobacteria,46Q72@74030|Roseovarius	28211|Alphaproteobacteria	S	Invasion associated locus B (IalB) protein	MA20_19790	-	-	-	-	-	-	-	-	-	-	-	IalB
CMS1_k127_1162234_0	391613.RTM1035_07398	2.621e-268	833.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,46QEZ@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function DUF87	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
CMS1_k127_1171079_3	1288298.rosmuc_00433	2.8e-209	655.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWK9@28211|Alphaproteobacteria,46NRU@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
CMS1_k127_1171079_1	314264.ROS217_08805	2.472e-227	707.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,46PZ6@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the thiolase family	bktB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_1171079_4	391613.RTM1035_19621	1.612e-111	364.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,46QIF@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
CMS1_k127_1171079_0	1354722.JQLS01000008_gene3665	1e-322	990.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,46PXU@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS1_k127_1171079_2	1288298.rosmuc_00428	2.033e-212	662.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,46Q7D@74030|Roseovarius	28211|Alphaproteobacteria	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_1172640_1	1354722.JQLS01000008_gene2442	3.993e-100	334.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,46QCE@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	fadD3	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS1_k127_1172640_2	1461694.ATO9_16865	3.861e-68	244.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2V9H5@28211|Alphaproteobacteria,2PFNX@252301|Oceanicola	28211|Alphaproteobacteria	G	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_1172640_0	1354722.JQLS01000008_gene2443	2.376e-207	648.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,46P2K@74030|Roseovarius	28211|Alphaproteobacteria	T	Sensory box histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_7,Response_reg
CMS1_k127_1183265_2	89187.ISM_15460	4.966e-50	179.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,46QW4@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS1_k127_1183265_1	1354722.JQLS01000008_gene1243	3.072e-71	242.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,46QYY@74030|Roseovarius	28211|Alphaproteobacteria	S	metal-sulfur cluster biosynthetic enzyme	mrp	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS1_k127_1183265_0	1288298.rosmuc_01372	1.517e-273	846.0	COG0189@1|root,COG4067@1|root,COG0189@2|Bacteria,COG4067@2|Bacteria,1MX62@1224|Proteobacteria,2TRUH@28211|Alphaproteobacteria,46P83@74030|Roseovarius	28211|Alphaproteobacteria	HJO	protein conserved in archaea	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK,Zn_protease
CMS1_k127_1183265_3	89187.ISM_15495	7.658e-08	55.0	COG1585@1|root,COG1585@2|Bacteria,1NA05@1224|Proteobacteria,2UFXG@28211|Alphaproteobacteria,46R6Z@74030|Roseovarius	28211|Alphaproteobacteria	OU	COG1585 Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS1_k127_1195843_0	1354722.JQLS01000008_gene653	8.88e-193	617.0	COG1024@1|root,COG1024@2|Bacteria,1R75Q@1224|Proteobacteria,2U51C@28211|Alphaproteobacteria,46PV6@74030|Roseovarius	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_1195843_3	1354722.JQLS01000008_gene652	3.614e-15	83.0	2B814@1|root,3218X@2|Bacteria,1QE1K@1224|Proteobacteria,2V3HC@28211|Alphaproteobacteria,46R98@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1195843_2	1354722.JQLS01000008_gene651	1.625e-46	169.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,2UCF1@28211|Alphaproteobacteria,46R0X@74030|Roseovarius	28211|Alphaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dskA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_1195843_1	1354722.JQLS01000008_gene650	1.516e-48	181.0	COG1868@1|root,COG1868@2|Bacteria,1RCV4@1224|Proteobacteria,2UAZ3@28211|Alphaproteobacteria,46PJE@74030|Roseovarius	28211|Alphaproteobacteria	N	COG1868 Flagellar motor switch protein	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliMN_C
CMS1_k127_119673_0	1288298.rosmuc_00537	0.0	1223.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2TRG0@28211|Alphaproteobacteria,46NYY@74030|Roseovarius	28211|Alphaproteobacteria	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
CMS1_k127_119673_6	1380367.JIBC01000007_gene1062	1.566e-24	106.0	2C91B@1|root,33D4Z@2|Bacteria,1NBNB@1224|Proteobacteria,2UFPM@28211|Alphaproteobacteria,3ZY0W@60136|Sulfitobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_119673_4	89187.ISM_15310	2.441e-71	244.0	COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,2U580@28211|Alphaproteobacteria,46NUI@74030|Roseovarius	28211|Alphaproteobacteria	K	transcriptional regulator, AsnC family	grp	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS1_k127_119673_5	1354722.JQLS01000008_gene1110	1.346e-50	182.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,2UBXR@28211|Alphaproteobacteria,46QY4@74030|Roseovarius	28211|Alphaproteobacteria	P	COG2076 Membrane transporters of cations and cationic drugs	qacE	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
CMS1_k127_119673_3	1354722.JQLS01000008_gene1112	1.66e-140	453.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,46NJ4@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS1_k127_119673_2	1354722.JQLS01000008_gene1113	1.824e-144	462.0	COG0697@1|root,COG0697@2|Bacteria,1MXR0@1224|Proteobacteria,2TR9E@28211|Alphaproteobacteria,46QAC@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_119673_1	314264.ROS217_21722	4.744e-181	569.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,46Q4K@74030|Roseovarius	28211|Alphaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_1223199_0	1469613.JT55_16000	0.0	1170.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,3FCVM@34008|Rhodovulum	28211|Alphaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_1223199_1	1123247.AUIJ01000002_gene2319	1.333e-148	472.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_1227272_0	1288298.rosmuc_03288	0.0	1099.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,46Q8H@74030|Roseovarius	28211|Alphaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_1227272_11	1294273.roselon_02016	1.024e-53	191.0	COG2329@1|root,COG2329@2|Bacteria,1RCYM@1224|Proteobacteria,2U7PT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1227272_7	1288298.rosmuc_03287	1.215e-111	363.0	COG0406@1|root,COG0406@2|Bacteria,1R0FR@1224|Proteobacteria,2U20M@28211|Alphaproteobacteria,46P8Q@74030|Roseovarius	28211|Alphaproteobacteria	G	Phosphoglycerate mutase family protein	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS1_k127_1227272_9	314264.ROS217_21897	2.79e-93	310.0	COG0625@1|root,COG0625@2|Bacteria,1MWUG@1224|Proteobacteria,2TTZ6@28211|Alphaproteobacteria,46Q8P@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	gstB	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N
CMS1_k127_1227272_4	644107.SL1157_1345	1.089e-190	599.0	COG0686@1|root,COG0686@2|Bacteria,1MXDG@1224|Proteobacteria,2TSFN@28211|Alphaproteobacteria,4NB1W@97050|Ruegeria	28211|Alphaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	sdh	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_N
CMS1_k127_1227272_1	1288298.rosmuc_03283	4.726e-219	682.0	COG1748@1|root,COG1748@2|Bacteria,1MY1G@1224|Proteobacteria,2U0RS@28211|Alphaproteobacteria,46NNY@74030|Roseovarius	28211|Alphaproteobacteria	E	And related proteins	lys2	-	1.4.1.18,1.5.1.10	ko:K00293,ko:K19064	ko00300,ko00310,ko00960,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map00960,map01100,map01110,map01130,map01230	M00030,M00032	R00446,R02315,R02317	RC00062,RC00215,RC00225,RC00694	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS1_k127_1227272_12	1288298.rosmuc_03367	1.543e-50	181.0	2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,2UBV9@28211|Alphaproteobacteria,46R3K@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3775)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3775
CMS1_k127_1227272_6	391613.RTM1035_11100	2.348e-125	406.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,2U27Q@28211|Alphaproteobacteria,46PT5@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1227272_8	391613.RTM1035_11105	9.403e-97	318.0	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,2U8XN@28211|Alphaproteobacteria,46QKP@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
CMS1_k127_1227272_3	1354722.JQLS01000008_gene997	8.176e-195	617.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2U1DI@28211|Alphaproteobacteria,46P2Y@74030|Roseovarius	28211|Alphaproteobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS1_k127_1227272_5	351016.RAZWK3B_04130	6.639e-137	441.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,2P236@2433|Roseobacter	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
CMS1_k127_1227272_2	1305735.JAFT01000005_gene2503	1.948e-213	669.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2TQUH@28211|Alphaproteobacteria,2PC70@252301|Oceanicola	28211|Alphaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
CMS1_k127_1227272_10	1354722.JQLS01000008_gene994	5.381e-80	274.0	COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,2U9G0@28211|Alphaproteobacteria,46PF2@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_1228755_5	570967.JMLV01000014_gene2083	1.263e-62	228.0	COG3637@1|root,COG5338@1|root,COG3637@2|Bacteria,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria,2U090@28211|Alphaproteobacteria,2JQS1@204441|Rhodospirillales	204441|Rhodospirillales	M	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
CMS1_k127_1228755_6	1123393.KB891316_gene1613	7.133e-52	199.0	2C1AX@1|root,33GUX@2|Bacteria,1MZSH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1228755_0	1354722.JQLS01000008_gene2658	0.0	1774.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,46Q0V@74030|Roseovarius	28211|Alphaproteobacteria	V	COG0841 Cation multidrug efflux pump	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS1_k127_1228755_2	314264.ROS217_05334	9.208e-176	557.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2TSW4@28211|Alphaproteobacteria,46Q34@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_D23
CMS1_k127_1228755_4	314264.ROS217_05339	6.121e-72	250.0	COG1309@1|root,COG1309@2|Bacteria,1N321@1224|Proteobacteria,2UE3A@28211|Alphaproteobacteria,46Q45@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1228755_1	1354722.JQLS01000008_gene3718	0.0	1657.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2TRIR@28211|Alphaproteobacteria,46Q91@74030|Roseovarius	28211|Alphaproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	phaAB	-	-	ko:K05559	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
CMS1_k127_1228755_7	1354722.JQLS01000008_gene3719	1.941e-50	183.0	COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,2UA52@28211|Alphaproteobacteria,46QWY@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1006 Multisubunit Na H antiporter, MnhC subunit	phaC	-	-	ko:K05560	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Oxidored_q2
CMS1_k127_1228755_3	1354722.JQLS01000008_gene3720	1.255e-137	443.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,46PTC@74030|Roseovarius	28211|Alphaproteobacteria	CP	COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	phaD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
CMS1_k127_124905_2	1123360.thalar_00149	9.724e-19	85.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS1_k127_124905_1	1354722.JQLS01000008_gene100	7.592e-200	622.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,46NYB@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS1_k127_124905_0	266809.PM03_08690	3.131e-240	750.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_1252824_0	314264.ROS217_17287	2.298e-150	477.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,46P6E@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CMS1_k127_1252824_1	1288298.rosmuc_03179	1.701e-79	269.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,46PKE@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	MA20_30780	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_1269102_7	314264.ROS217_07320	6.789e-07	51.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,46NZ8@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
CMS1_k127_1269102_3	391595.RLO149_c005720	1.61e-164	520.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2TTJ6@28211|Alphaproteobacteria,2P43D@2433|Roseobacter	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_1269102_4	391595.RLO149_c005730	2.899e-143	463.0	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2U1YB@28211|Alphaproteobacteria,2P497@2433|Roseobacter	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
CMS1_k127_1269102_1	375451.RD1_3860	8.122e-231	716.0	COG4948@1|root,COG4948@2|Bacteria,1R63G@1224|Proteobacteria,2TT3A@28211|Alphaproteobacteria,2P201@2433|Roseobacter	28211|Alphaproteobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1269102_6	314256.OG2516_01019	1.421e-114	372.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,2TS23@28211|Alphaproteobacteria,2PDU0@252301|Oceanicola	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
CMS1_k127_1269102_5	1342299.Z947_2253	7.685e-135	442.0	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2TQVJ@28211|Alphaproteobacteria,3ZUWN@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	urtD	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_1269102_2	1342299.Z947_2252	4.164e-228	710.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TTN2@28211|Alphaproteobacteria,3ZWI1@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	urtC	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
CMS1_k127_1269102_0	1342302.JASC01000013_gene2859	1.777e-314	974.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,3ZVBV@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
CMS1_k127_1277030_2	351016.RAZWK3B_20281	2.695e-153	486.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2P2AI@2433|Roseobacter	28211|Alphaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_1277030_0	314264.ROS217_23647	1.086e-284	880.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria,46NT2@74030|Roseovarius	28211|Alphaproteobacteria	FP	Phosphatase, Ppx GppA family protein	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS1_k127_1277030_6	1288298.rosmuc_02046	1.763e-49	179.0	2E45M@1|root,32Z1N@2|Bacteria,1N788@1224|Proteobacteria,2UFVB@28211|Alphaproteobacteria,46QUX@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1277030_1	1354722.JQLS01000008_gene2010	1.288e-172	546.0	COG2374@1|root,COG2374@2|Bacteria,1NTH6@1224|Proteobacteria,2TVN3@28211|Alphaproteobacteria,46PEU@74030|Roseovarius	28211|Alphaproteobacteria	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_1277030_3	1449351.RISW2_08090	3.191e-106	348.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2TTX1@28211|Alphaproteobacteria,4KK77@93682|Roseivivax	28211|Alphaproteobacteria	O	DnaJ molecular chaperone homology domain	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
CMS1_k127_1277030_5	391613.RTM1035_12948	3.904e-67	233.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria,46QSP@74030|Roseovarius	28211|Alphaproteobacteria	M	COG1247 Sortase and related acyltransferases	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS1_k127_1277030_4	1354722.JQLS01000008_gene2013	4.789e-93	309.0	COG0346@1|root,COG0346@2|Bacteria,1RD81@1224|Proteobacteria,2U7VR@28211|Alphaproteobacteria,46NXS@74030|Roseovarius	28211|Alphaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
CMS1_k127_1283902_3	314264.ROS217_06620	6.594e-27	110.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,46QVD@74030|Roseovarius	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_1283902_1	1288298.rosmuc_03849	7.578e-102	334.0	COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2U4DJ@28211|Alphaproteobacteria,46NY0@74030|Roseovarius	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_1283902_0	1288298.rosmuc_03850	3.309e-256	794.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,46NMU@74030|Roseovarius	28211|Alphaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1283902_2	272942.RCAP_rcc01898	4.399e-41	159.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,1FCAX@1060|Rhodobacter	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_1283902_4	1443111.JASG01000004_gene3672	2.947e-17	84.0	COG3509@1|root,COG3509@2|Bacteria,1R9H9@1224|Proteobacteria,2U31M@28211|Alphaproteobacteria,3ZUVQ@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Phospholipase/Carboxylesterase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
CMS1_k127_1284490_12	1288298.rosmuc_02629	8.542e-46	167.0	2E3T7@1|root,31AE7@2|Bacteria,1Q5F1@1224|Proteobacteria,2VBTC@28211|Alphaproteobacteria,46RZ2@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1284490_15	1354722.JQLS01000008_gene1164	2.09e-22	100.0	2DRS8@1|root,33CUB@2|Bacteria,1QV1W@1224|Proteobacteria,2UJDK@28211|Alphaproteobacteria,46S4F@74030|Roseovarius	28211|Alphaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS1_k127_1284490_10	1288298.rosmuc_03478	3.021e-64	222.0	COG0589@1|root,COG0589@2|Bacteria,1RHZG@1224|Proteobacteria,2U792@28211|Alphaproteobacteria,46QQJ@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspF	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_1284490_14	1288298.rosmuc_03477	7.449e-35	135.0	2BYIU@1|root,33719@2|Bacteria,1N8CW@1224|Proteobacteria,2UG1N@28211|Alphaproteobacteria,46R2H@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1284490_11	1354722.JQLS01000008_gene1160	3.578e-53	189.0	COG1359@1|root,COG1359@2|Bacteria,1RHSN@1224|Proteobacteria,2U9WY@28211|Alphaproteobacteria,46QXU@74030|Roseovarius	28211|Alphaproteobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_1284490_8	314264.ROS217_21592	7.403e-80	280.0	29KTS@1|root,307R7@2|Bacteria,1N8YZ@1224|Proteobacteria,2UH2V@28211|Alphaproteobacteria,46PSS@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1284490_0	314264.ROS217_21597	0.0	1257.0	COG5434@1|root,COG5434@2|Bacteria,1MVBW@1224|Proteobacteria,2TVNM@28211|Alphaproteobacteria,46NCS@74030|Roseovarius	28211|Alphaproteobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
CMS1_k127_1284490_13	314264.ROS217_15071	4.783e-43	162.0	COG2010@1|root,COG2010@2|Bacteria,1QXW0@1224|Proteobacteria,2TXCX@28211|Alphaproteobacteria,46QVE@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_1284490_5	351016.RAZWK3B_20226	3.187e-174	550.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,2P1DJ@2433|Roseobacter	28211|Alphaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	comC	-	1.1.1.338	ko:K16844	ko00270,ko01120,map00270,map01120	-	R07137	RC00031	ko00000,ko00001,ko01000	-	-	-	Ldh_2
CMS1_k127_1284490_6	388399.SSE37_22587	1.061e-103	341.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS1_k127_1284490_3	314264.ROS217_15086	8.546e-242	751.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,46QED@74030|Roseovarius	28211|Alphaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS1_k127_1284490_9	1110502.TMO_0612	2.853e-67	235.0	COG1225@1|root,COG1225@2|Bacteria,1MWJP@1224|Proteobacteria,2TSSW@28211|Alphaproteobacteria,2JTR6@204441|Rhodospirillales	204441|Rhodospirillales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CMS1_k127_1284490_1	391613.RTM1035_04470	8.865e-283	871.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,46P6N@74030|Roseovarius	28211|Alphaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS1_k127_1284490_4	1288298.rosmuc_02050	4.222e-179	566.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,46P1W@74030|Roseovarius	28211|Alphaproteobacteria	S	AI-2E family transporter	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
CMS1_k127_1284490_7	1288298.rosmuc_02049	1.359e-100	331.0	COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,46QG7@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0593 ATPase involved in DNA replication initiation	hda	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA
CMS1_k127_1284490_2	1354722.JQLS01000008_gene2006	6.267e-261	812.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,46Q4A@74030|Roseovarius	28211|Alphaproteobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_1294233_3	1288298.rosmuc_00215	1.419e-43	159.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,46PDC@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_1294233_2	391624.OIHEL45_18026	1.289e-113	375.0	28HZ8@1|root,2Z84E@2|Bacteria,1QJN2@1224|Proteobacteria,2U05T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1403,HTH_13
CMS1_k127_1294233_1	1002340.AFCF01000034_gene3571	2.822e-206	649.0	COG5527@1|root,COG5527@2|Bacteria,1QBGA@1224|Proteobacteria,2TUPV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Protein involved in initiation of plasmid replication	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
CMS1_k127_1294233_0	999547.KI421501_gene4051	2.13e-267	827.0	COG1192@1|root,COG1192@2|Bacteria,1MVJU@1224|Proteobacteria,2TRYQ@28211|Alphaproteobacteria,2829P@191028|Leisingera	28211|Alphaproteobacteria	D	Anion-transporting ATPase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_1296361_2	985054.JQEZ01000001_gene2949	1.05e-17	83.0	COG1802@1|root,COG1802@2|Bacteria,1P945@1224|Proteobacteria,2TV2V@28211|Alphaproteobacteria,4NCU1@97050|Ruegeria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_1296361_0	985054.JQEZ01000001_gene2948	9.926e-178	559.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2TTWT@28211|Alphaproteobacteria,4ND43@97050|Ruegeria	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	dapA_1	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_1296361_1	1354722.JQLS01000008_gene1897	5.472e-93	306.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46NJI@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	dhaL	-	1.2.1.99	ko:K09472	ko00330,ko01100,map00330,map01100	M00136	R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_1306755_2	314264.ROS217_15500	2.812e-11	64.0	COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,2U75R@28211|Alphaproteobacteria,46QIX@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0735 Fe2 Zn2 uptake regulation proteins	fur	-	-	ko:K09826	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_1306755_1	391613.RTM1035_13153	2.223e-110	356.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,2TV8S@28211|Alphaproteobacteria,46NP4@74030|Roseovarius	28211|Alphaproteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_1306755_0	314265.R2601_08811	5.044e-181	569.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TQYV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_1314467_3	1208323.B30_19118	8.349e-83	278.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.24	ko:K22270	ko00362,ko01120,map00362,map01120	-	R02589	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
CMS1_k127_1314467_0	314265.R2601_20376	3.114e-239	746.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1314467_4	1208323.B30_19108	1.311e-64	224.0	COG3090@1|root,COG3090@2|Bacteria,1RK5Q@1224|Proteobacteria,2UAJ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_1314467_1	1415756.JQMY01000001_gene3528	3.412e-165	525.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TQVT@28211|Alphaproteobacteria,2PCTP@252301|Oceanicola	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_1314467_5	1208323.B30_19098	1.642e-54	195.0	COG1846@1|root,COG1846@2|Bacteria,1RJPG@1224|Proteobacteria,2TUJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	MarR family	MA20_28880	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_1314467_2	1105367.CG50_00855	8.311e-103	340.0	COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,2TRCE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	3-carboxy-cis,cis-muconate cycloisomerase	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
CMS1_k127_1325174_2	89187.ISM_12310	2.165e-11	66.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U08R@28211|Alphaproteobacteria,46Q89@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit	frdB	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
CMS1_k127_1325174_0	1288298.rosmuc_00204	3.285e-288	889.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria,46PMP@74030|Roseovarius	28211|Alphaproteobacteria	S	Circularly permuted ATP-grasp type 2	MA20_32420	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
CMS1_k127_1325174_1	1288298.rosmuc_00203	1.591e-163	517.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2TQUM@28211|Alphaproteobacteria,46PY8@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_32425	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CMS1_k127_1344643_0	314264.ROS217_05084	3.918e-249	775.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TT7Y@28211|Alphaproteobacteria,46PA7@74030|Roseovarius	28211|Alphaproteobacteria	GM	And related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1344643_1	391613.RTM1035_15702	7.03e-157	504.0	COG1216@1|root,COG1216@2|Bacteria,1MYU7@1224|Proteobacteria,2TT17@28211|Alphaproteobacteria,46NAQ@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
CMS1_k127_1344643_2	314264.ROS217_05094	1.725e-22	98.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria,46PI1@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1349595_0	1288298.rosmuc_00731	0.0	1052.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,46PES@74030|Roseovarius	28211|Alphaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS1_k127_1349595_1	1121479.AUBS01000014_gene1155	0.0	1020.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_1349595_2	571166.KI421509_gene1874	5.281e-189	595.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_1362827_5	1288298.rosmuc_02718	2.689e-82	276.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,46REJ@74030|Roseovarius	28211|Alphaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	nirE	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS1_k127_1362827_9	644107.SL1157_A0195	9.148e-33	130.0	COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2UGBE@28211|Alphaproteobacteria,4NCI2@97050|Ruegeria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	nirC	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K19344	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
CMS1_k127_1362827_3	1354722.JQLS01000008_gene1172	8.774e-138	443.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2TVCB@28211|Alphaproteobacteria,46RQ0@74030|Roseovarius	28211|Alphaproteobacteria	S	Cytochrome D1 heme domain	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
CMS1_k127_1362827_8	571166.KI421509_gene3319	5.553e-65	222.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2TVCB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cytochrome D1 heme domain	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
CMS1_k127_1362827_1	1288298.rosmuc_02721	1.233e-151	484.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2U1S8@28211|Alphaproteobacteria,46RJQ@74030|Roseovarius	28211|Alphaproteobacteria	K	overlaps another CDS with the same product name	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
CMS1_k127_1362827_7	1288298.rosmuc_02722	2.715e-65	230.0	COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,2U81N@28211|Alphaproteobacteria,46RV2@74030|Roseovarius	28211|Alphaproteobacteria	K	AsnC-type helix-turn-helix domain	nirG	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
CMS1_k127_1362827_6	1123360.thalar_02350	1.462e-77	264.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,2U84D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator AsnC family	nirH	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
CMS1_k127_1362827_2	292415.Tbd_0071	7.58e-149	482.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,1KSZD@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_1362827_0	1288298.rosmuc_02725	3.102e-286	884.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2TVHI@28211|Alphaproteobacteria,46RDK@74030|Roseovarius	28211|Alphaproteobacteria	C	Cytochrome D1 heme domain	nirN	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Cytochrome_CBB3
CMS1_k127_1362827_4	391613.RTM1035_16002	3.882e-97	323.0	COG2138@1|root,COG2138@2|Bacteria,1RJC9@1224|Proteobacteria,2U9UG@28211|Alphaproteobacteria,46NTH@74030|Roseovarius	28211|Alphaproteobacteria	S	CbiX	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
CMS1_k127_1367076_1	314265.R2601_14295	9.399e-127	417.0	COG0438@1|root,COG0438@2|Bacteria,1RJ6C@1224|Proteobacteria,2U50C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1367076_0	391613.RTM1035_13978	1.712e-189	596.0	COG3307@1|root,COG3307@2|Bacteria,1MV4S@1224|Proteobacteria,2TV8W@28211|Alphaproteobacteria,46NF0@74030|Roseovarius	28211|Alphaproteobacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1412237_6	391613.RTM1035_15027	2.307e-55	194.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,46QEV@74030|Roseovarius	28211|Alphaproteobacteria	M	shape-determining protein	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_1412237_2	1288298.rosmuc_03751	1.349e-210	657.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,46PPA@74030|Roseovarius	28211|Alphaproteobacteria	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_1412237_1	314264.ROS217_04909	3.776e-236	737.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,46P1I@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS1_k127_1412237_7	351016.RAZWK3B_10221	4.966e-47	172.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2UCCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_1412237_4	351016.RAZWK3B_10216	2.137e-80	273.0	2CN5Z@1|root,32SGB@2|Bacteria,1N1FB@1224|Proteobacteria,2UBV1@28211|Alphaproteobacteria,2P33A@2433|Roseobacter	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2948)	MA20_21100	-	-	-	-	-	-	-	-	-	-	-	DUF2948
CMS1_k127_1412237_0	1354722.JQLS01000008_gene2448	8.408e-247	765.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,46PS4@74030|Roseovarius	28211|Alphaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_1412237_9	314264.ROS217_04894	2.189e-10	62.0	2DHEU@1|root,2ZZH3@2|Bacteria,1Q5KQ@1224|Proteobacteria,2VBY6@28211|Alphaproteobacteria,46RBP@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1412237_3	1354722.JQLS01000008_gene2447	7.34e-186	585.0	COG0697@1|root,COG0697@2|Bacteria,1Q50Z@1224|Proteobacteria,2VBFA@28211|Alphaproteobacteria,46RNQ@74030|Roseovarius	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1412237_8	985054.JQEZ01000001_gene2761	4.624e-32	132.0	COG5470@1|root,COG5470@2|Bacteria,1NE6C@1224|Proteobacteria,2UF8J@28211|Alphaproteobacteria,4NCV4@97050|Ruegeria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_1412237_5	246200.SPO3301	1.426e-69	243.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,4NC3V@97050|Ruegeria	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1415045_1	391613.RTM1035_01200	1.475e-177	561.0	COG3487@1|root,COG3487@2|Bacteria,1MX5H@1224|Proteobacteria,2TRMF@28211|Alphaproteobacteria,46PUS@74030|Roseovarius	28211|Alphaproteobacteria	M	iron-regulated protein	irpA	-	-	ko:K07231	-	-	-	-	ko00000	-	-	-	Peptidase_M75
CMS1_k127_1415045_3	391613.RTM1035_18650	4.947e-135	433.0	COG1838@1|root,COG1838@2|Bacteria,1MVNG@1224|Proteobacteria,2TTHD@28211|Alphaproteobacteria,46PJH@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	ttdB	-	4.2.1.32	ko:K03780	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase_C
CMS1_k127_1415045_2	1123360.thalar_00555	6.923e-162	518.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_1415045_0	472175.EL18_00426	7.529e-198	618.0	COG1951@1|root,COG1951@2|Bacteria,1MW8J@1224|Proteobacteria,2U0X2@28211|Alphaproteobacteria,43MPA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Fumarate hydratase (Fumerase)	ttdA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
CMS1_k127_1415529_0	351016.RAZWK3B_05702	0.0	1283.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2P239@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	sardh	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS1_k127_1416646_2	391613.RTM1035_17532	3.568e-68	233.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,46Q3D@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_1416646_3	314264.ROS217_10742	1.194e-16	80.0	2EJDS@1|root,33D4T@2|Bacteria,1NIZJ@1224|Proteobacteria,2UK2S@28211|Alphaproteobacteria,46R93@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1416646_0	1288298.rosmuc_00010	2.886e-236	736.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,46QKI@74030|Roseovarius	28211|Alphaproteobacteria	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_1416646_1	1120983.KB894575_gene775	1.398e-82	287.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,1JPPV@119043|Rhodobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
CMS1_k127_1429157_0	443152.MDG893_15467	4.857e-60	225.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_1431414_17	1354722.JQLS01000008_gene238	7.854e-72	247.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U1B8@28211|Alphaproteobacteria,46Q8F@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0657 Esterase lipase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
CMS1_k127_1431414_4	1354722.JQLS01000008_gene239	5.213e-195	609.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,46PA9@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CMS1_k127_1431414_19	1354722.JQLS01000008_gene240	8.858e-44	163.0	COG0792@1|root,COG0792@2|Bacteria,1PSPH@1224|Proteobacteria,2V4T3@28211|Alphaproteobacteria,46QRH@74030|Roseovarius	28211|Alphaproteobacteria	L	related to archaeal Holliday junction resolvase	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS1_k127_1431414_10	1354722.JQLS01000008_gene241	6.949e-137	440.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,46NU8@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS1_k127_1431414_5	1288298.rosmuc_01847	9.392e-193	607.0	COG0683@1|root,COG0683@2|Bacteria,1QURG@1224|Proteobacteria,2TS62@28211|Alphaproteobacteria,46NPF@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	MA20_24635	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_1431414_0	1288298.rosmuc_01848	0.0	1627.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,46P45@74030|Roseovarius	28211|Alphaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism	glnD	GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
CMS1_k127_1431414_6	1423144.Gal_02904	2.068e-173	546.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,34ENT@302485|Phaeobacter	28211|Alphaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS1_k127_1431414_2	1288298.rosmuc_00299	0.0	1048.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,46QA9@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS1_k127_1431414_14	1288298.rosmuc_00298	5.244e-95	317.0	28NII@1|root,2ZBJY@2|Bacteria,1RAAN@1224|Proteobacteria,2U5W9@28211|Alphaproteobacteria,46QCJ@74030|Roseovarius	28211|Alphaproteobacteria	S	MOSC domain protein	yuaD	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS1_k127_1431414_9	1354722.JQLS01000008_gene3706	2.473e-147	468.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,2TU5T@28211|Alphaproteobacteria,46P8V@74030|Roseovarius	28211|Alphaproteobacteria	S	COG4106 Trans-aconitate methyltransferase	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_1431414_1	1288298.rosmuc_00296	0.0	1208.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,46Q2B@74030|Roseovarius	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_1431414_8	1354722.JQLS01000008_gene3708	3.57e-151	490.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,46NF7@74030|Roseovarius	28211|Alphaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
CMS1_k127_1431414_13	314264.ROS217_08159	1.32e-117	386.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,46NGI@74030|Roseovarius	28211|Alphaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
CMS1_k127_1431414_15	1354722.JQLS01000008_gene3710	1.224e-85	286.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,46NXF@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS1_k127_1431414_3	1354722.JQLS01000008_gene3711	8.658e-254	786.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,46NEP@74030|Roseovarius	28211|Alphaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_1431414_7	1354722.JQLS01000008_gene3712	3.049e-160	514.0	COG3266@1|root,COG3266@2|Bacteria,1PZDQ@1224|Proteobacteria,2U2MW@28211|Alphaproteobacteria,46Q9N@74030|Roseovarius	28211|Alphaproteobacteria	S	Cell division and transport-associated protein TolA	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
CMS1_k127_1431414_16	314264.ROS217_08179	1.136e-78	264.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,46QCW@74030|Roseovarius	28211|Alphaproteobacteria	U	COG0848 Biopolymer transport protein	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
CMS1_k127_1431414_11	314264.ROS217_08184	2.215e-129	418.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria,46Q9B@74030|Roseovarius	28211|Alphaproteobacteria	U	COG0811 Biopolymer transport proteins	tolQ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
CMS1_k127_1431414_18	1354722.JQLS01000008_gene3717	3.518e-55	196.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria,46R2E@74030|Roseovarius	28211|Alphaproteobacteria	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
CMS1_k127_1431414_12	1288298.rosmuc_02607	6.493e-123	399.0	COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,2U5HC@28211|Alphaproteobacteria,46QXP@74030|Roseovarius	28211|Alphaproteobacteria	K	COG2188 Transcriptional regulators	-	-	-	ko:K05836	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
CMS1_k127_1431414_20	1288298.rosmuc_02606	8.23e-21	92.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,2TR3A@28211|Alphaproteobacteria,46Q5U@74030|Roseovarius	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	hutF	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS1_k127_1439832_0	1354722.JQLS01000008_gene601	1.827e-191	603.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2TTF9@28211|Alphaproteobacteria,46P3V@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS1_k127_1439832_1	391613.RTM1035_06003	1.517e-127	413.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria,46Q62@74030|Roseovarius	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_16345	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_1447046_3	1288298.rosmuc_01149	1.37e-45	167.0	2EACX@1|root,334GT@2|Bacteria,1N8Z0@1224|Proteobacteria,2UFXD@28211|Alphaproteobacteria,46R0Y@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1447046_1	391613.RTM1035_06698	2.091e-151	482.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,46P03@74030|Roseovarius	28211|Alphaproteobacteria	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS1_k127_1447046_0	1288298.rosmuc_01147	3.422e-232	722.0	COG2807@1|root,COG2807@2|Bacteria,1QV77@1224|Proteobacteria,2TT90@28211|Alphaproteobacteria,46Q2P@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_1447046_2	1288298.rosmuc_01146	4.158e-101	330.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,46NP0@74030|Roseovarius	28211|Alphaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
CMS1_k127_1451841_0	571166.KI421509_gene2480	8.111e-134	432.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2TR7U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
CMS1_k127_1451841_3	1288298.rosmuc_00325	6.515e-67	229.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,46QRC@74030|Roseovarius	28211|Alphaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS1_k127_1451841_1	1288298.rosmuc_00476	1.058e-107	351.0	COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,2U7DA@28211|Alphaproteobacteria,46NPT@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_44640	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
CMS1_k127_1451841_2	1354722.JQLS01000008_gene3624	1.033e-81	274.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,46QCK@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0714 MoxR-like ATPases	moxR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_1463104_1	351016.RAZWK3B_17763	1.434e-240	747.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria,2P2I8@2433|Roseobacter	28211|Alphaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_1463104_5	1288298.rosmuc_02834	4.41e-199	626.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,46NJK@74030|Roseovarius	28211|Alphaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS1_k127_1463104_6	1288298.rosmuc_02024	2.966e-160	511.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,46NQF@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1045 Serine acetyltransferase	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS1_k127_1463104_3	314264.ROS217_15605	3.353e-214	672.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,46PJM@74030|Roseovarius	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_1463104_2	195105.CN97_06815	2.548e-232	725.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
CMS1_k127_1463104_4	1288298.rosmuc_02892	5.486e-202	631.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,46QE3@74030|Roseovarius	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS1_k127_1463104_8	596151.DesfrDRAFT_3897	1.927e-51	192.0	COG0500@1|root,COG2226@2|Bacteria,1PEBD@1224|Proteobacteria,42T7H@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25,Methyltransf_31
CMS1_k127_1463104_9	1288298.rosmuc_02883	1.108e-43	162.0	COG2919@1|root,COG2919@2|Bacteria,1MZH9@1224|Proteobacteria,2UC4I@28211|Alphaproteobacteria,46QWN@74030|Roseovarius	28211|Alphaproteobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CMS1_k127_1463104_0	1354722.JQLS01000008_gene2134	5.764e-276	857.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQU2@28211|Alphaproteobacteria,46NAC@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
CMS1_k127_1463104_7	1354722.JQLS01000008_gene2135	3.75e-57	203.0	COG2044@1|root,COG2044@2|Bacteria,1N8Y2@1224|Proteobacteria,2U973@28211|Alphaproteobacteria,46QQY@74030|Roseovarius	28211|Alphaproteobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS1_k127_1463104_10	391613.RTM1035_04805	5.432e-19	86.0	COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,46QJW@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA polymerase III, chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
CMS1_k127_1484154_6	1288298.rosmuc_01122	1.303e-113	370.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,46P4G@74030|Roseovarius	28211|Alphaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_1484154_1	314264.ROS217_16850	1.778e-232	725.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2TU1V@28211|Alphaproteobacteria,46QAX@74030|Roseovarius	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS1_k127_1484154_8	1354722.JQLS01000008_gene718	8.597e-50	181.0	COG2340@1|root,COG2340@2|Bacteria,1PE4F@1224|Proteobacteria,2VBPS@28211|Alphaproteobacteria,46S05@74030|Roseovarius	28211|Alphaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS1_k127_1484154_0	1123237.Salmuc_04195	3.085e-238	742.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TSZ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	atzB	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_1484154_5	1288298.rosmuc_01120	6.219e-120	392.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,46Q3H@74030|Roseovarius	28211|Alphaproteobacteria	G	and related enzymes of inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_1484154_7	391613.RTM1035_06548	5.529e-64	220.0	COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria,46QSY@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulators	phrR	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
CMS1_k127_1484154_2	391613.RTM1035_06543	1.786e-169	536.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,46NJ9@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1484154_3	314264.ROS217_16830	1.856e-147	470.0	COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,2TUC6@28211|Alphaproteobacteria,46NHR@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	yofA	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1484154_10	1354722.JQLS01000008_gene713	5.549e-14	77.0	COG5457@1|root,COG5457@2|Bacteria,1NH01@1224|Proteobacteria,2V30G@28211|Alphaproteobacteria,46R8R@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1127
CMS1_k127_1484154_4	1354722.JQLS01000008_gene712	3.717e-144	460.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,46QE7@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0670 Integral membrane protein, interacts with FtsH	ybhL	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
CMS1_k127_1484154_9	391613.RTM1035_05600	1.106e-46	174.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS1_k127_1489938_1	351016.RAZWK3B_13279	1.613e-174	548.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,2P1TT@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1489938_2	1288298.rosmuc_01497	1.716e-34	136.0	2BUVE@1|root,32Q7A@2|Bacteria,1Q4HP@1224|Proteobacteria,2VAZN@28211|Alphaproteobacteria,46R77@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1489938_0	314264.ROS217_20812	5.262e-275	853.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRII@28211|Alphaproteobacteria,46PB7@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acsA_1	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_150130_9	1354722.JQLS01000008_gene2367	2.397e-69	238.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2U9F7@28211|Alphaproteobacteria,46QRX@74030|Roseovarius	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_150130_3	314264.ROS217_04305	3.472e-114	369.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria,46PM2@74030|Roseovarius	28211|Alphaproteobacteria	S	NYN domain	MA20_36560	-	-	-	-	-	-	-	-	-	-	-	NYN
CMS1_k127_150130_8	1354722.JQLS01000008_gene2365	1.066e-70	244.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,46Q1C@74030|Roseovarius	28211|Alphaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS1_k127_150130_10	1354722.JQLS01000008_gene2364	1.746e-63	220.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,46QYB@74030|Roseovarius	28211|Alphaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS1_k127_150130_0	1354722.JQLS01000008_gene2363	0.0	1350.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,46P1A@74030|Roseovarius	28211|Alphaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_150130_4	1288298.rosmuc_01770	5.215e-114	370.0	COG3216@1|root,COG3216@2|Bacteria,1QA1I@1224|Proteobacteria,2TS9W@28211|Alphaproteobacteria,46QHU@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
CMS1_k127_150130_2	1354722.JQLS01000008_gene2361	5.463e-142	454.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,46NZI@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS1_k127_150130_7	391613.RTM1035_14322	1.447e-76	258.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,46QQ3@74030|Roseovarius	28211|Alphaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS1_k127_150130_1	314264.ROS217_04350	5.424e-166	524.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,46P20@74030|Roseovarius	28211|Alphaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS1_k127_150130_5	1288298.rosmuc_01776	1.959e-113	370.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,46NXJ@74030|Roseovarius	28211|Alphaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS1_k127_150130_6	89187.ISM_13815	2.036e-106	349.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,46QKZ@74030|Roseovarius	28211|Alphaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS1_k127_1504096_3	1354722.JQLS01000008_gene720	8.745e-69	234.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,46P4G@74030|Roseovarius	28211|Alphaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_1504096_2	351016.RAZWK3B_20436	5.437e-85	286.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,2P308@2433|Roseobacter	28211|Alphaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	MA20_17975	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS1_k127_1504096_1	1288298.rosmuc_00995	4.149e-88	291.0	COG1764@1|root,COG1764@2|Bacteria,1RHVR@1224|Proteobacteria,2U7CX@28211|Alphaproteobacteria,46NPJ@74030|Roseovarius	28211|Alphaproteobacteria	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_1504096_0	391613.RTM1035_15637	1.455e-152	484.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,2TS4S@28211|Alphaproteobacteria,46P9D@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_17970	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
CMS1_k127_1504474_4	666509.RCA23_c28280	1.292e-77	261.0	COG1638@1|root,COG1638@2|Bacteria,1PG0D@1224|Proteobacteria,2TTUQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_1504474_2	1002340.AFCF01000057_gene1994	8.019e-203	644.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,34EXI@302485|Phaeobacter	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_1504474_0	351016.RAZWK3B_09546	4.669e-240	754.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2P4DV@2433|Roseobacter	28211|Alphaproteobacteria	T	COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system	-	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
CMS1_k127_1504474_1	314264.ROS217_11241	7.633e-206	644.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,46NJT@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	mdlB	-	1.1.2.3,1.1.99.31	ko:K00101,ko:K15054	ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120	-	R00196,R04160,R07664	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
CMS1_k127_1504474_3	375451.RD1_3813	3.569e-83	277.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TUEF@28211|Alphaproteobacteria,2P0ZQ@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	MA20_15005	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_1504599_18	1354722.JQLS01000008_gene3532	2.203e-10	61.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,46PGX@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0785 Cytochrome c biogenesis protein	soxV	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS1_k127_1504599_16	1354722.JQLS01000008_gene3531	4.719e-45	167.0	COG0526@1|root,COG0526@2|Bacteria,1MZH0@1224|Proteobacteria,2UCBJ@28211|Alphaproteobacteria,46QXZ@74030|Roseovarius	28211|Alphaproteobacteria	CO	Regulatory protein SoxS	soxS	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1504599_15	314264.ROS217_09525	1.487e-45	169.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,46QZM@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS1_k127_1504599_8	1354722.JQLS01000008_gene3529	5.631e-176	556.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2TRUQ@28211|Alphaproteobacteria,46NG0@74030|Roseovarius	28211|Alphaproteobacteria	S	YeeE YedE family protein	soxT	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_1504599_13	314264.ROS217_09545	8.438e-65	223.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2U99K@28211|Alphaproteobacteria,46QQA@74030|Roseovarius	28211|Alphaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_1504599_12	391613.RTM1035_18680	2.808e-67	231.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,46QN3@74030|Roseovarius	28211|Alphaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_1504599_10	1354722.JQLS01000008_gene978	3.183e-135	435.0	COG1414@1|root,COG1414@2|Bacteria,1R3Q3@1224|Proteobacteria,2TWNY@28211|Alphaproteobacteria,46RUE@74030|Roseovarius	28211|Alphaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_1504599_0	1354722.JQLS01000008_gene979	2.6e-305	940.0	COG0747@1|root,COG0747@2|Bacteria,1MWGY@1224|Proteobacteria,2TR73@28211|Alphaproteobacteria,46RER@74030|Roseovarius	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1504599_7	1354722.JQLS01000008_gene980	4.055e-176	555.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TU5S@28211|Alphaproteobacteria,46RQP@74030|Roseovarius	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1504599_9	1354722.JQLS01000008_gene981	4.341e-169	534.0	COG1173@1|root,COG1173@2|Bacteria,1MXGS@1224|Proteobacteria,2TTQ7@28211|Alphaproteobacteria,46S32@74030|Roseovarius	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1504599_6	1354722.JQLS01000008_gene982	3.339e-186	584.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,46RIG@74030|Roseovarius	28211|Alphaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1504599_5	1354722.JQLS01000008_gene983	3.982e-192	608.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,46RFD@74030|Roseovarius	28211|Alphaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1504599_1	1354722.JQLS01000008_gene984	1.146e-280	869.0	COG0405@1|root,COG0405@2|Bacteria,1MXXD@1224|Proteobacteria,2TSB2@28211|Alphaproteobacteria,46RNW@74030|Roseovarius	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	MA20_09815	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_1504599_2	1354722.JQLS01000008_gene985	3.262e-272	844.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TTGM@28211|Alphaproteobacteria,46RR4@74030|Roseovarius	28211|Alphaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_1504599_4	1354722.JQLS01000008_gene53	4.626e-195	615.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2U4U4@28211|Alphaproteobacteria,46NDD@74030|Roseovarius	28211|Alphaproteobacteria	T	COG3448 CBS-domain-containing membrane protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
CMS1_k127_1504599_3	391937.NA2_13702	8.853e-225	709.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,43GU8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system large permease component	dctM	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1504599_14	1547437.LL06_13490	5.32e-59	211.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2TT9A@28211|Alphaproteobacteria,43RMT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_1504599_11	935548.KI912159_gene2095	2.216e-117	387.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,2TU0X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1504599_17	89187.ISM_03890	4.286e-37	141.0	COG2084@1|root,COG2084@2|Bacteria,1MV48@1224|Proteobacteria,2U0FZ@28211|Alphaproteobacteria,46QSD@74030|Roseovarius	28211|Alphaproteobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_1514857_2	1354722.JQLS01000008_gene635	5.751e-113	364.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,46PB9@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0439 Biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS1_k127_1514857_4	314264.ROS217_06585	2.226e-93	311.0	2F10M@1|root,33U26@2|Bacteria,1QYR6@1224|Proteobacteria,2TXX5@28211|Alphaproteobacteria,46NRW@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1514857_3	1288298.rosmuc_03842	4.693e-104	341.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,46NQV@74030|Roseovarius	28211|Alphaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS1_k127_1514857_6	314264.ROS217_06600	4.709e-76	258.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2UCHU@28211|Alphaproteobacteria,46QTM@74030|Roseovarius	28211|Alphaproteobacteria	Q	Involved in resistance to organic solvents, periplasmic component	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_1514857_5	391613.RTM1035_15337	2.081e-76	257.0	COG3761@1|root,COG3761@2|Bacteria,1RHS3@1224|Proteobacteria,2U95G@28211|Alphaproteobacteria,46QN5@74030|Roseovarius	28211|Alphaproteobacteria	C	COG3761 NADH ubiquinone oxidoreductase 17.2 kD subunit	MA20_29090	-	1.6.99.3	ko:K00356	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	NDUFA12
CMS1_k127_1514857_0	1354722.JQLS01000008_gene2611	1.887e-260	805.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2TS3R@28211|Alphaproteobacteria,46PI5@74030|Roseovarius	28211|Alphaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS1_k127_1514857_1	1288298.rosmuc_03847	8.215e-124	398.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,46NA1@74030|Roseovarius	28211|Alphaproteobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_1514857_7	314264.ROS217_06620	1.988e-24	103.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,46QVD@74030|Roseovarius	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_1515467_1	1354722.JQLS01000008_gene1328	6.232e-90	297.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,46NWP@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0785 Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS1_k127_1515467_0	391613.RTM1035_07784	1.009e-205	645.0	COG0596@1|root,COG0596@2|Bacteria,1MXCB@1224|Proteobacteria,2TU0S@28211|Alphaproteobacteria,46NW1@74030|Roseovarius	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1520072_11	1288298.rosmuc_00510	2.608e-15	75.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,46NP8@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_1520072_6	1353537.TP2_13785	8.793e-136	434.0	COG1024@1|root,COG1024@2|Bacteria,1PBA3@1224|Proteobacteria,2U4FD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_1520072_1	1288298.rosmuc_00508	3.451e-241	750.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,46PSP@74030|Roseovarius	28211|Alphaproteobacteria	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_1520072_8	1354722.JQLS01000008_gene3653	9.138e-89	297.0	COG1309@1|root,COG1309@2|Bacteria,1RJI2@1224|Proteobacteria,2UA3D@28211|Alphaproteobacteria,46NCH@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1520072_0	1354722.JQLS01000008_gene3652	0.0	1131.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,46P97@74030|Roseovarius	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS1_k127_1520072_7	314264.ROS217_08895	5.391e-135	433.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,46QKV@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ptr1	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_1520072_2	391613.RTM1035_20001	5.598e-160	508.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,46PA6@74030|Roseovarius	28211|Alphaproteobacteria	P	K -dependent Na Ca exchanger related-protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_1520072_10	89187.ISM_10031	1.339e-20	92.0	2EHUS@1|root,33BKE@2|Bacteria,1NI4N@1224|Proteobacteria,2UK8G@28211|Alphaproteobacteria,46R8W@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1520072_4	1354722.JQLS01000008_gene3649	1.947e-141	454.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TQZP@28211|Alphaproteobacteria,46P0T@74030|Roseovarius	28211|Alphaproteobacteria	OU	COG0616 Periplasmic serine proteases (ClpP class)	sohB	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_1520072_5	314264.ROS217_08915	5.347e-138	444.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,46N9U@74030|Roseovarius	28211|Alphaproteobacteria	V	COG0842 ABC-type multidrug transport system, permease component	yadH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_1520072_3	391613.RTM1035_19981	1.153e-159	508.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,46NS2@74030|Roseovarius	28211|Alphaproteobacteria	V	COG1131 ABC-type multidrug transport system, ATPase component	hndI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_1520072_9	351016.RAZWK3B_02120	9.32e-77	261.0	COG2755@1|root,COG2755@2|Bacteria,1RC2Z@1224|Proteobacteria,2U5PG@28211|Alphaproteobacteria,2P380@2433|Roseobacter	28211|Alphaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_1524660_5	1305735.JAFT01000005_gene625	3.869e-140	447.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,2PCYG@252301|Oceanicola	28211|Alphaproteobacteria	K	transcriptional regulatory protein	MA20_17930	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS1_k127_1524660_6	391613.RTM1035_04310	6.573e-125	406.0	COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,2TRSW@28211|Alphaproteobacteria,46NC2@74030|Roseovarius	28211|Alphaproteobacteria	K	Chromosome replication initiation inhibitor protein	-	-	-	ko:K05596	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1524660_7	1288298.rosmuc_02801	3.151e-99	327.0	COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,2U583@28211|Alphaproteobacteria,46Q0J@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1279 Lysine efflux permease	argO	-	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
CMS1_k127_1524660_4	1354722.JQLS01000008_gene2254	2.079e-149	477.0	COG0697@1|root,COG0697@2|Bacteria,1MX07@1224|Proteobacteria,2TQNT@28211|Alphaproteobacteria,46QHA@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1524660_1	314264.ROS217_14926	5.116e-192	602.0	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,2TS8Y@28211|Alphaproteobacteria,46PFE@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4175 ABC-type proline glycine betaine transport system, ATPase component	choV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran
CMS1_k127_1524660_3	391613.RTM1035_04330	7.035e-152	482.0	COG4176@1|root,COG4176@2|Bacteria,1QTTE@1224|Proteobacteria,2TS3U@28211|Alphaproteobacteria,46PIJ@74030|Roseovarius	28211|Alphaproteobacteria	P	COG4176 ABC-type proline glycine betaine transport system, permease component	choW	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
CMS1_k127_1524660_2	1354722.JQLS01000008_gene2251	2.117e-167	531.0	COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,2TRV8@28211|Alphaproteobacteria,46Q04@74030|Roseovarius	28211|Alphaproteobacteria	E	COG2113 ABC-type proline glycine betaine transport systems, periplasmic components	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
CMS1_k127_1524660_0	314264.ROS217_14941	6.814e-299	920.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,46NGP@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1524660_8	1288298.rosmuc_02807	4.442e-94	310.0	COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,2U5RY@28211|Alphaproteobacteria,46Q19@74030|Roseovarius	28211|Alphaproteobacteria	K	Repressor involved in choline regulation of the bet genes	betI	-	-	ko:K02167	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_6,TetR_N
CMS1_k127_1527793_7	314264.ROS217_21612	7.135e-94	310.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,46PX6@74030|Roseovarius	28211|Alphaproteobacteria	I	Acyl-carrier-protein S-malonyltransferase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS1_k127_1527793_1	314264.ROS217_21617	1.226e-183	582.0	COG2353@1|root,COG3038@1|root,COG2353@2|Bacteria,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2UBYU@28211|Alphaproteobacteria,46PEM@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,YceI
CMS1_k127_1527793_9	391613.RTM1035_10620	6.681e-25	105.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2UF4N@28211|Alphaproteobacteria,46R9D@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the UPF0434 family	MA20_24965	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
CMS1_k127_1527793_6	1354722.JQLS01000008_gene1152	2.405e-123	396.0	COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,46P13@74030|Roseovarius	28211|Alphaproteobacteria	S	to the N-terminal domain of Lon protease	lonD	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
CMS1_k127_1527793_2	391613.RTM1035_10630	2.96e-159	506.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,46PRM@74030|Roseovarius	28211|Alphaproteobacteria	O	COG3118 Thioredoxin domain-containing protein	trxA2	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS1_k127_1527793_4	439497.RR11_1904	1.847e-156	495.0	COG0708@1|root,COG0708@2|Bacteria,1MVMC@1224|Proteobacteria,2TRWQ@28211|Alphaproteobacteria,4N9U6@97050|Ruegeria	28211|Alphaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA2	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_1527793_8	351016.RAZWK3B_04560	2.55e-62	224.0	COG1432@1|root,COG1432@2|Bacteria,1RJ33@1224|Proteobacteria,2U9MF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
CMS1_k127_1527793_5	1288298.rosmuc_03465	6.795e-138	446.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,2TR97@28211|Alphaproteobacteria,46QJR@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mtrA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1527793_0	314264.ROS217_21647	1.615e-193	608.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,2TR82@28211|Alphaproteobacteria,46PME@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
CMS1_k127_1527793_3	1288298.rosmuc_01246	2.651e-157	500.0	COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria,2U17B@28211|Alphaproteobacteria,46Q8Z@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0591 Na proline symporter	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_1533291_1	1038860.AXAP01000010_gene7674	5.626e-72	250.0	COG1309@1|root,COG1309@2|Bacteria,1MZEP@1224|Proteobacteria,2TQNA@28211|Alphaproteobacteria,3JU9M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1533291_2	504832.OCAR_6243	6.403e-58	206.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2U9MT@28211|Alphaproteobacteria,3K12D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_1533291_3	1354722.JQLS01000008_gene1668	7.86e-34	132.0	COG1977@1|root,COG1977@2|Bacteria,1NN1V@1224|Proteobacteria,2UJVE@28211|Alphaproteobacteria,46R4Q@74030|Roseovarius	28211|Alphaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_1533291_0	391613.RTM1035_07539	0.0	1133.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,46PXQ@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_16003_0	351016.RAZWK3B_19291	0.0	1180.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria,2P28P@2433|Roseobacter	28211|Alphaproteobacteria	H	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
CMS1_k127_16003_2	314264.ROS217_22757	7.944e-138	441.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,46Q0M@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator	MA20_15060	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
CMS1_k127_16003_3	314264.ROS217_12116	5.467e-100	334.0	COG0596@1|root,COG0596@2|Bacteria,1P6EB@1224|Proteobacteria,2TXDP@28211|Alphaproteobacteria,46QI6@74030|Roseovarius	28211|Alphaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_16003_1	314264.ROS217_12111	1.315e-150	479.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2U1Z7@28211|Alphaproteobacteria,46PU0@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1606246_3	1354722.JQLS01000008_gene1079	3.607e-40	149.0	COG5448@1|root,COG5448@2|Bacteria,1MXM8@1224|Proteobacteria,2TTJ3@28211|Alphaproteobacteria,46QIK@74030|Roseovarius	28211|Alphaproteobacteria	S	Conserved hypothetical protein 2217 (DUF2460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
CMS1_k127_1606246_1	1354722.JQLS01000008_gene1080	1.211e-155	495.0	COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2TTWS@28211|Alphaproteobacteria,46PHM@74030|Roseovarius	28211|Alphaproteobacteria	S	Phage conserved hypothetical protein BR0599	-	-	-	-	-	-	-	-	-	-	-	-	DUF2163,Phage_BR0599
CMS1_k127_1606246_2	314264.ROS217_18037	1.688e-78	263.0	COG0791@1|root,COG0791@2|Bacteria,1RK6X@1224|Proteobacteria,2U93K@28211|Alphaproteobacteria,46QT5@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
CMS1_k127_1606246_0	1354722.JQLS01000008_gene1082	0.0	1872.0	COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria,46PZ9@74030|Roseovarius	28211|Alphaproteobacteria	S	GTA TIM-barrel-like domain	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM,Phage-tail_3
CMS1_k127_1606922_2	391613.RTM1035_06593	1.65e-18	84.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,46P5P@74030|Roseovarius	28211|Alphaproteobacteria	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_1606922_0	314264.ROS217_22657	1.892e-190	599.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,46QBU@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS1_k127_1606922_1	391613.RTM1035_06583	3.546e-131	426.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,46Q0U@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS1_k127_1609875_4	1305735.JAFT01000005_gene1077	1.68e-41	153.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2PCVT@252301|Oceanicola	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	pfkB	-	2.7.1.20,2.7.1.4	ko:K00847,ko:K00856	ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100	-	R00185,R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_1609875_2	391613.RTM1035_20391	4.094e-148	471.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,46P91@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_1609875_0	1402135.SUH3_10075	1.13e-152	491.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,3ZVUG@60136|Sulfitobacter	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS1_k127_1609875_1	1354722.JQLS01000008_gene2943	6.749e-151	478.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,46QEX@74030|Roseovarius	28211|Alphaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS1_k127_1609875_3	314264.ROS217_11756	3.492e-53	190.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria,46Q38@74030|Roseovarius	28211|Alphaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_1621393_0	391613.RTM1035_16107	0.0	1792.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,46NJY@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA polymerase III, alpha subunit	dnaE	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS1_k127_1621393_2	391613.RTM1035_16112	3.187e-225	707.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2TR3Q@28211|Alphaproteobacteria,46NSF@74030|Roseovarius	28211|Alphaproteobacteria	C	COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
CMS1_k127_1621393_1	1288298.rosmuc_00657	0.0	1018.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2TTAB@28211|Alphaproteobacteria,46PX3@74030|Roseovarius	28211|Alphaproteobacteria	C	COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_1629361_6	314264.ROS217_18357	1.319e-133	429.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,46NW3@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1629361_8	999611.KI421504_gene2743	1.159e-106	348.0	COG1396@1|root,COG1396@2|Bacteria,1R6PS@1224|Proteobacteria,2TT0B@28211|Alphaproteobacteria,280FM@191028|Leisingera	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS1_k127_1629361_3	314264.ROS217_20937	4.344e-232	726.0	COG4191@1|root,COG4191@2|Bacteria,1MVK7@1224|Proteobacteria,2TR44@28211|Alphaproteobacteria,46NGQ@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	regM	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS1_k127_1629361_2	391613.RTM1035_08804	1.16e-258	808.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TU0K@28211|Alphaproteobacteria,46PEV@74030|Roseovarius	28211|Alphaproteobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_1629361_7	1354722.JQLS01000008_gene1566	1.14e-122	400.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,2U6DE@28211|Alphaproteobacteria,46PR1@74030|Roseovarius	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	merA_1	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_1629361_11	1366046.HIMB11_01169	2.011e-19	89.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2UJCE@28211|Alphaproteobacteria,3ZHX7@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_1629361_9	1354722.JQLS01000008_gene1564	9.766e-49	178.0	COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,46R1N@74030|Roseovarius	28211|Alphaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS1_k127_1629361_10	1354722.JQLS01000008_gene1563	4.641e-39	147.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,46R5Q@74030|Roseovarius	28211|Alphaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS1_k127_1629361_4	351016.RAZWK3B_15218	2.473e-190	599.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TT0P@28211|Alphaproteobacteria,2P28B@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family	speB_1	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS1_k127_1629361_1	314264.ROS217_20907	1.315e-276	858.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,46NVV@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205,1.7.1.7	ko:K00088,ko:K00364	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R01134,R08240	RC00143,RC00457,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
CMS1_k127_1629361_5	314264.ROS217_20902	6.289e-153	492.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,46PNA@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	sun1	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
CMS1_k127_1629361_0	1354722.JQLS01000008_gene1560	1.227e-311	967.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,46NH1@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	cckA	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_1629684_2	314264.ROS217_05139	3.109e-180	569.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,46QBE@74030|Roseovarius	28211|Alphaproteobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_1629684_0	1288298.rosmuc_02655	6.698e-286	885.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,46PXN@74030|Roseovarius	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.44,6.2.1.48	ko:K00666,ko:K02182,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1629684_7	1469613.JT55_12015	4.016e-136	438.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,3FCQ8@34008|Rhodovulum	28211|Alphaproteobacteria	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_1629684_8	391613.RTM1035_16212	3.718e-95	318.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,46NWT@74030|Roseovarius	28211|Alphaproteobacteria	G	haloacid dehalogenase-like hydrolase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_1629684_3	1288298.rosmuc_00674	1.834e-166	528.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,46P75@74030|Roseovarius	28211|Alphaproteobacteria	S	related to 2-nitropropane dioxygenase	MA20_36475	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS1_k127_1629684_1	1288298.rosmuc_00673	1.954e-243	756.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TUHU@28211|Alphaproteobacteria,46P47@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	dapE2	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_1629684_6	89187.ISM_10516	8.802e-140	451.0	COG0414@1|root,COG0414@2|Bacteria,1PIC2@1224|Proteobacteria,2V8RI@28211|Alphaproteobacteria,46PIB@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_1629684_5	1354722.JQLS01000008_gene87	7.691e-145	462.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2TQT1@28211|Alphaproteobacteria,46Q2M@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS1_k127_1629684_4	1305735.JAFT01000005_gene1934	1.511e-152	490.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2TT7U@28211|Alphaproteobacteria,2PD9E@252301|Oceanicola	28211|Alphaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
CMS1_k127_1630591_0	1354722.JQLS01000008_gene2410	2.375e-192	603.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2TQXW@28211|Alphaproteobacteria,46NDY@74030|Roseovarius	28211|Alphaproteobacteria	I	COG4553 Poly-beta-hydroxyalkanoate depolymerase	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
CMS1_k127_1630591_2	391613.RTM1035_14632	2.584e-114	373.0	COG2021@1|root,COG2021@2|Bacteria,1RDEH@1224|Proteobacteria,2U267@28211|Alphaproteobacteria,46NGU@74030|Roseovarius	28211|Alphaproteobacteria	E	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_1630591_1	351016.RAZWK3B_12152	1.526e-128	414.0	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2P19Z@2433|Roseobacter	28211|Alphaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	MA20_24420	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4
CMS1_k127_1630591_3	1288298.rosmuc_01686	1.047e-25	107.0	2EDX5@1|root,337S6@2|Bacteria,1NAFN@1224|Proteobacteria,2UF7Q@28211|Alphaproteobacteria,46RAJ@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_163641_1	391619.PGA1_c02320	8.258e-128	409.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2TR8G@28211|Alphaproteobacteria,34GDU@302485|Phaeobacter	28211|Alphaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_163641_0	1449351.RISW2_17565	8.775e-171	540.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_163641_2	1469613.JT55_01545	6.848e-46	167.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2TT0R@28211|Alphaproteobacteria,3FCHV@34008|Rhodovulum	28211|Alphaproteobacteria	GM	Mannose-6-phosphate isomerase	cpsB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS1_k127_1637848_17	1123247.AUIJ01000017_gene2737	1.849e-31	125.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS1_k127_1637848_2	1123247.AUIJ01000017_gene2736	2.064e-195	614.0	COG0687@1|root,COG0687@2|Bacteria,1MU12@1224|Proteobacteria,2U060@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0687 Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CMS1_k127_1637848_18	1268622.AVS7_02337	7.556e-15	84.0	2DYSD@1|root,32V5Y@2|Bacteria,1N2G9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CMS1_k127_1637848_0	314264.ROS217_10547	0.0	1262.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,46Q71@74030|Roseovarius	28211|Alphaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_1637848_3	314264.ROS217_10542	5.065e-170	537.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2U0CA@28211|Alphaproteobacteria,46PM7@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
CMS1_k127_1637848_7	351016.RAZWK3B_05377	4.326e-129	416.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,2P115@2433|Roseobacter	28211|Alphaproteobacteria	C	Belongs to the HpcH HpaI aldolase family	hpcH	-	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_1637848_6	351016.RAZWK3B_05392	3.738e-139	448.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2TRXD@28211|Alphaproteobacteria,2P2NG@2433|Roseobacter	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1637848_5	314264.ROS217_10527	7.951e-162	512.0	COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,46NGX@74030|Roseovarius	28211|Alphaproteobacteria	D	COG1192 ATPases involved in chromosome partitioning	mipZ	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MipZ
CMS1_k127_1637848_12	1354722.JQLS01000008_gene3123	4.49e-90	301.0	COG3916@1|root,COG3916@2|Bacteria,1MWPW@1224|Proteobacteria,2TVJ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Acyl-homoserine-lactone synthase	raiI	-	2.3.1.184	ko:K20249	ko00270,ko01100,ko02024,map00270,map01100,map02024	-	R08940	RC00021,RC00039	ko00000,ko00001,ko01000	-	-	-	Autoind_synth
CMS1_k127_1637848_1	391613.RTM1035_19591	5.315e-297	914.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,46PH1@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member	recD2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
CMS1_k127_1637848_11	1188256.BASI01000007_gene2262	3.31e-105	346.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ycdF	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1637848_15	1353537.TP2_13275	1.934e-58	212.0	2CEES@1|root,324ED@2|Bacteria,1RM4K@1224|Proteobacteria,2UA2K@28211|Alphaproteobacteria,2XP8Q@285107|Thioclava	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1637848_8	1354722.JQLS01000008_gene3119	4.756e-120	401.0	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,2TQWW@28211|Alphaproteobacteria,46Q8A@74030|Roseovarius	28211|Alphaproteobacteria	S	Putative transmembrane protein (Alph_Pro_TM)	MA20_19830	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
CMS1_k127_1637848_4	1354722.JQLS01000008_gene3118	2.397e-166	527.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2TRIC@28211|Alphaproteobacteria,46PHA@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane transporter protein	MA20_19835	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_1637848_16	391613.RTM1035_19566	2.005e-45	168.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,46R2T@74030|Roseovarius	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_1637848_14	351016.RAZWK3B_04635	1.01e-62	221.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,2P38W@2433|Roseobacter	28211|Alphaproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_1637848_10	314264.ROS217_10487	2.102e-107	350.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,46PUQ@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0694 Thioredoxin-like proteins and domains	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
CMS1_k127_1637848_13	314264.ROS217_10482	3.444e-85	287.0	COG0589@1|root,COG0589@2|Bacteria,1R9XB@1224|Proteobacteria,2U59E@28211|Alphaproteobacteria,46P6B@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	MA20_23830	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_1637848_9	1354722.JQLS01000008_gene3113	5.208e-120	388.0	2CJVZ@1|root,2Z84M@2|Bacteria,1MVJ0@1224|Proteobacteria,2TTJI@28211|Alphaproteobacteria,46NAF@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1643568_1	391613.RTM1035_13578	2.853e-56	197.0	COG0741@1|root,COG0741@2|Bacteria,1N5Z6@1224|Proteobacteria,2U1GR@28211|Alphaproteobacteria,46P8X@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_1643568_0	314264.ROS217_03755	7.198e-252	782.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,46NJS@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0308 Aminopeptidase N	pepN	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
CMS1_k127_1647355_0	351016.RAZWK3B_10602	3.304e-190	596.0	COG0687@1|root,COG0687@2|Bacteria,1QTFJ@1224|Proteobacteria,2V9Q6@28211|Alphaproteobacteria,2P553@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0687 Spermidine putrescine-binding periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
CMS1_k127_1647355_2	571166.KI421509_gene1808	2.203e-134	433.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2VF9H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_1647355_1	351016.RAZWK3B_10592	3.489e-165	522.0	COG1176@1|root,COG1176@2|Bacteria,1PFEG@1224|Proteobacteria,2V9DK@28211|Alphaproteobacteria,2P4WC@2433|Roseobacter	28211|Alphaproteobacteria	P	COG1176 ABC-type spermidine putrescine transport system, permease component I	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_1647355_3	1288298.rosmuc_00353	1.186e-115	375.0	COG0583@1|root,COG0583@2|Bacteria,1PMTG@1224|Proteobacteria,2TV35@28211|Alphaproteobacteria,46NSH@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1656385_1	1354722.JQLS01000008_gene76	7.507e-171	539.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TUGD@28211|Alphaproteobacteria,46PYJ@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS1_k127_1656385_0	1354722.JQLS01000008_gene75	4.566e-265	822.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2UPJ8@28211|Alphaproteobacteria,46QGP@74030|Roseovarius	28211|Alphaproteobacteria	S	ABC transporter, ATP-binding protein	MA20_34815	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
CMS1_k127_1656385_2	1002340.AFCF01000013_gene2737	3.073e-121	398.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,2TUI0@28211|Alphaproteobacteria,34EX6@302485|Phaeobacter	28211|Alphaproteobacteria	O	XdhC and CoxI family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS1_k127_1656385_3	1469613.JT55_13555	6.281e-14	72.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2TTAB@28211|Alphaproteobacteria,3FCIN@34008|Rhodovulum	28211|Alphaproteobacteria	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_1666954_7	314264.ROS217_13291	1.18e-54	205.0	COG2982@1|root,COG2982@2|Bacteria,1MY1T@1224|Proteobacteria,2TS9U@28211|Alphaproteobacteria,46NEH@74030|Roseovarius	28211|Alphaproteobacteria	M	Uncharacterized protein conserved in bacteria (DUF2125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2125
CMS1_k127_1666954_4	1354722.JQLS01000008_gene292	2.981e-129	419.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TUSA@28211|Alphaproteobacteria,46PRC@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1666954_5	314264.ROS217_13281	8.239e-100	329.0	COG1024@1|root,COG1024@2|Bacteria,1MWYA@1224|Proteobacteria,2TV62@28211|Alphaproteobacteria,46PUW@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_1666954_8	1122614.JHZF01000014_gene2710	7.005e-47	169.0	COG1403@1|root,COG1403@2|Bacteria,1MZVF@1224|Proteobacteria,2UBUF@28211|Alphaproteobacteria,2PEA8@252301|Oceanicola	28211|Alphaproteobacteria	V	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_1666954_1	391613.RTM1035_03310	1.819e-225	705.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,46PRX@74030|Roseovarius	28211|Alphaproteobacteria	M	Mechanosensitive ion channel family protein	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS1_k127_1666954_2	391613.RTM1035_03305	7.618e-177	562.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TR1K@28211|Alphaproteobacteria,46N9F@74030|Roseovarius	28211|Alphaproteobacteria	S	FAD binding domain	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS1_k127_1666954_6	571166.KI421509_gene2778	3.622e-70	242.0	COG0625@1|root,COG0625@2|Bacteria,1RAIN@1224|Proteobacteria,2U5JR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
CMS1_k127_1666954_3	1288298.rosmuc_02436	2.957e-175	556.0	COG1466@1|root,COG1466@2|Bacteria,1R8PA@1224|Proteobacteria,2U1KQ@28211|Alphaproteobacteria,46NS0@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS1_k127_1666954_9	1288298.rosmuc_02435	5.847e-46	170.0	COG5468@1|root,COG5468@2|Bacteria,1N2BX@1224|Proteobacteria,2UC7X@28211|Alphaproteobacteria,46QQX@74030|Roseovarius	28211|Alphaproteobacteria	S	Lipopolysaccharide-assembly	-	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
CMS1_k127_1666954_0	1288298.rosmuc_02434	0.0	1472.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,46Q5W@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_166804_0	1354722.JQLS01000008_gene3556	0.0	1354.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,46P46@74030|Roseovarius	28211|Alphaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS1_k127_166804_4	1002340.AFCF01000025_gene909	1.28e-44	162.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,34FR8@302485|Phaeobacter	28211|Alphaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS1_k127_166804_3	351016.RAZWK3B_03720	1.872e-93	319.0	COG2931@1|root,COG2931@2|Bacteria,1N161@1224|Proteobacteria,2UDXT@28211|Alphaproteobacteria,2P39W@2433|Roseobacter	28211|Alphaproteobacteria	Q	Type I secretion target repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS1_k127_166804_1	744979.R2A130_1240	1.137e-152	487.0	COG2084@1|root,COG2084@2|Bacteria,1PU4S@1224|Proteobacteria,2TT0X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_166804_2	1354722.JQLS01000008_gene3560	8.232e-131	419.0	COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,2TQM4@28211|Alphaproteobacteria,46PUD@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LacI family	-	-	-	ko:K06145	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CMS1_k127_1670643_0	1469613.JT55_17545	1.49e-172	543.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,3FCHC@34008|Rhodovulum	28211|Alphaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_1670643_2	1288298.rosmuc_02842	1.959e-83	278.0	COG1522@1|root,COG1522@2|Bacteria,1RCYP@1224|Proteobacteria,2U799@28211|Alphaproteobacteria,46PPQ@74030|Roseovarius	28211|Alphaproteobacteria	K	transcriptional regulator, AsnC family	-	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS1_k127_1670643_3	314264.ROS217_15041	5.305e-82	274.0	COG1522@1|root,COG1522@2|Bacteria,1RAP6@1224|Proteobacteria,2U5FX@28211|Alphaproteobacteria,46PJB@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, AsnC family	-	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS1_k127_1670643_1	314264.ROS217_15305	9.486e-95	314.0	COG2931@1|root,COG2931@2|Bacteria,1R6NH@1224|Proteobacteria,2U10I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_1673902_1	999549.KI421513_gene574	5.128e-144	462.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2TSYI@28211|Alphaproteobacteria,27ZNI@191028|Leisingera	28211|Alphaproteobacteria	P	Phosphate transporter family	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS1_k127_1673902_2	1002340.AFCF01000031_gene4159	2.7e-54	194.0	COG0494@1|root,COG0494@2|Bacteria,1MZ5D@1224|Proteobacteria,2UBX9@28211|Alphaproteobacteria,34FRE@302485|Phaeobacter	28211|Alphaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_1673902_0	1354722.JQLS01000008_gene112	0.0	1323.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,46NJA@74030|Roseovarius	28211|Alphaproteobacteria	L	COG1643 HrpA-like helicases	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
CMS1_k127_1695672_0	391624.OIHEL45_05435	4.864e-319	981.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type dipeptide transport system periplasmic component	dppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363	-	ko:K12368	ko02010,ko02030,map02010,map02030	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1695672_1	644107.SL1157_0097	4.966e-175	557.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TRQ5@28211|Alphaproteobacteria,4NA6D@97050|Ruegeria	28211|Alphaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_1695672_2	985054.JQEZ01000003_gene1418	9.748e-16	81.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,4NAKQ@97050|Ruegeria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	dppB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1720776_4	1288298.rosmuc_03516	6.218e-16	77.0	COG2346@1|root,COG2346@2|Bacteria,1MZSM@1224|Proteobacteria,2UCHK@28211|Alphaproteobacteria,46QQT@74030|Roseovarius	28211|Alphaproteobacteria	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS1_k127_1720776_0	314264.ROS217_19417	0.0	1073.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2TWNB@28211|Alphaproteobacteria,46QEK@74030|Roseovarius	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS1_k127_1720776_1	391613.RTM1035_09219	1.239e-143	462.0	COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,2TU53@28211|Alphaproteobacteria,46Q09@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF697)	MA20_04555	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08990	-	-	-	-	ko00000	-	-	-	DUF697
CMS1_k127_1720776_3	314264.ROS217_19407	3.89e-55	197.0	COG0454@1|root,COG0454@2|Bacteria,1N13B@1224|Proteobacteria,2UBYY@28211|Alphaproteobacteria,46QTW@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
CMS1_k127_1720776_2	1288298.rosmuc_01397	2.132e-97	320.0	COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,2TR9Y@28211|Alphaproteobacteria,46NV5@74030|Roseovarius	28211|Alphaproteobacteria	S	YcjX-like family, DUF463	MA20_04550	-	-	ko:K06918	-	-	-	-	ko00000	-	-	-	DUF463
CMS1_k127_1745652_6	396588.Tgr7_1943	3.628e-36	139.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,1SBT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent)	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
CMS1_k127_1745652_5	1417296.U879_19755	1.591e-45	171.0	2DNU1@1|root,32Z4S@2|Bacteria,1N8FB@1224|Proteobacteria,2UI55@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
CMS1_k127_1745652_7	391613.RTM1035_15267	2.358e-34	133.0	COG1872@1|root,COG1872@2|Bacteria,1PVGG@1224|Proteobacteria,2VB7U@28211|Alphaproteobacteria,46R6U@74030|Roseovarius	28211|Alphaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS1_k127_1745652_2	1288298.rosmuc_03831	8.941e-95	313.0	COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2U5MZ@28211|Alphaproteobacteria,46NXU@74030|Roseovarius	28211|Alphaproteobacteria	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_1745652_1	1288298.rosmuc_03832	4.117e-102	339.0	COG2981@1|root,COG2981@2|Bacteria,1MWAA@1224|Proteobacteria,2TT6E@28211|Alphaproteobacteria,46P2H@74030|Roseovarius	28211|Alphaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	MA20_24505	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
CMS1_k127_1745652_8	999549.KI421513_gene604	1.925e-33	133.0	COG5454@1|root,COG5454@2|Bacteria,1N778@1224|Proteobacteria,2UBS2@28211|Alphaproteobacteria,281SG@191028|Leisingera	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1467
CMS1_k127_1745652_4	985054.JQEZ01000001_gene2688	3.206e-79	265.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,2U728@28211|Alphaproteobacteria,4NC16@97050|Ruegeria	28211|Alphaproteobacteria	E	Methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS1_k127_1745652_3	314264.ROS217_06560	2.299e-87	294.0	COG2197@1|root,COG2197@2|Bacteria,1RA3V@1224|Proteobacteria,2U0I0@28211|Alphaproteobacteria,46PW1@74030|Roseovarius	28211|Alphaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_1745652_0	391613.RTM1035_14652	3.888e-127	410.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria,46PF9@74030|Roseovarius	28211|Alphaproteobacteria	J	Including N-acetylases of ribosomal proteins	-	GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_1745652_9	571166.KI421509_gene3493	5.169e-15	74.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_1749755_4	388399.SSE37_08123	9.107e-12	64.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS1_k127_1749755_1	1354722.JQLS01000008_gene2114	1.252e-194	612.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TS0W@28211|Alphaproteobacteria,46P3T@74030|Roseovarius	28211|Alphaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1749755_2	1288298.rosmuc_02902	1.524e-176	557.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TTC8@28211|Alphaproteobacteria,46NPZ@74030|Roseovarius	28211|Alphaproteobacteria	H	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	mtkB	-	6.2.1.5,6.2.1.9	ko:K01902,ko:K08692	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS1_k127_1749755_0	1354722.JQLS01000008_gene2116	1.925e-229	713.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,46NQG@74030|Roseovarius	28211|Alphaproteobacteria	H	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	mtkA	-	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_1749755_3	351016.RAZWK3B_13804	1.9e-81	271.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TU4H@28211|Alphaproteobacteria,2P2MS@2433|Roseobacter	28211|Alphaproteobacteria	H	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_1752270_6	1354722.JQLS01000008_gene3158	6.209e-94	309.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,46Q3Z@74030|Roseovarius	28211|Alphaproteobacteria	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_1752270_4	314264.ROS217_10647	9.817e-104	339.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2TSK7@28211|Alphaproteobacteria,46NQD@74030|Roseovarius	28211|Alphaproteobacteria	T	COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	regA	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
CMS1_k127_1752270_2	1288298.rosmuc_00929	2.907e-216	672.0	COG0463@1|root,COG0463@2|Bacteria,1MWA0@1224|Proteobacteria,2TTR5@28211|Alphaproteobacteria,46PF3@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
CMS1_k127_1752270_0	1354722.JQLS01000008_gene3155	0.0	1092.0	2CEUT@1|root,2Z8Z2@2|Bacteria,1ND0Q@1224|Proteobacteria,2TU4D@28211|Alphaproteobacteria,46NFJ@74030|Roseovarius	28211|Alphaproteobacteria	S	Core-2/I-Branching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Branch
CMS1_k127_1752270_1	1354722.JQLS01000008_gene3154	5.218e-261	809.0	COG4424@1|root,COG4424@2|Bacteria,1QGYC@1224|Proteobacteria,2TRKU@28211|Alphaproteobacteria,46NNQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS1_k127_1752270_7	1354722.JQLS01000008_gene3139	6.635e-80	268.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,46PI0@74030|Roseovarius	28211|Alphaproteobacteria	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS1_k127_1752270_5	391613.RTM1035_17522	3.195e-101	332.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,46NNF@74030|Roseovarius	28211|Alphaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
CMS1_k127_1752270_3	1354722.JQLS01000008_gene3141	6.837e-128	409.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,46PR5@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1137 ABC-type (unclassified) transport system, ATPase component	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_1754210_1	1288298.rosmuc_03492	1.549e-61	216.0	COG2931@1|root,COG2931@2|Bacteria,1N0J9@1224|Proteobacteria,2UE6B@28211|Alphaproteobacteria,46QTC@74030|Roseovarius	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_1754210_0	391613.RTM1035_10500	1.214e-199	631.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,46NFI@74030|Roseovarius	28211|Alphaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS1_k127_1769950_1	314264.ROS217_18392	3.116e-105	344.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,46PM4@74030|Roseovarius	28211|Alphaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS1_k127_1769950_0	1288298.rosmuc_03522	1.463e-235	730.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,46PRR@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	lldD	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
CMS1_k127_1773787_5	89187.ISM_11745	1.659e-88	292.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,46QFP@74030|Roseovarius	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_1773787_7	391613.RTM1035_13753	1.467e-69	240.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,46QT1@74030|Roseovarius	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CMS1_k127_1773787_8	1288298.rosmuc_01910	2.025e-62	217.0	2C112@1|root,32SUT@2|Bacteria,1N2WB@1224|Proteobacteria,2UC3U@28211|Alphaproteobacteria,46QY9@74030|Roseovarius	28211|Alphaproteobacteria	S	H-type lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	H_lectin
CMS1_k127_1773787_0	1354722.JQLS01000008_gene2482	4.959e-203	636.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,46Q6Y@74030|Roseovarius	28211|Alphaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_1773787_3	391613.RTM1035_03230	2.932e-110	359.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,2U07P@28211|Alphaproteobacteria,46NHV@74030|Roseovarius	28211|Alphaproteobacteria	G	COG3917 2-hydroxychromene-2-carboxylate isomerase	nahD	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_1773787_4	1354722.JQLS01000008_gene2480	4.264e-105	349.0	COG0596@1|root,COG0596@2|Bacteria,1NCX0@1224|Proteobacteria,2UEMT@28211|Alphaproteobacteria,46S4C@74030|Roseovarius	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_1773787_1	1354722.JQLS01000008_gene2479	9.742e-182	574.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,46NDQ@74030|Roseovarius	28211|Alphaproteobacteria	E	L-threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS1_k127_1773787_6	314264.ROS217_05029	1.653e-85	285.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,46PBR@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the UPF0260 family	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS1_k127_1773787_2	89187.ISM_11795	7.433e-121	390.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,46P6G@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS1_k127_1778611_1	1354722.JQLS01000008_gene2852	3.102e-22	96.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria,46NWR@74030|Roseovarius	28211|Alphaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS1_k127_1778611_0	1354722.JQLS01000008_gene2853	2.5e-295	908.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,46Q0S@74030|Roseovarius	28211|Alphaproteobacteria	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_1789860_7	351016.RAZWK3B_01260	1.91e-48	174.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,2P1SI@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
CMS1_k127_1789860_5	1354722.JQLS01000008_gene3592	2.675e-100	331.0	COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2TRBH@28211|Alphaproteobacteria,46NR2@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1802 Transcriptional regulators	-	-	-	ko:K11475	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
CMS1_k127_1789860_3	314264.ROS217_09200	2.074e-180	570.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,46PED@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_1789860_1	1354722.JQLS01000008_gene3590	5.983e-210	655.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,46NM6@74030|Roseovarius	28211|Alphaproteobacteria	BQ	Including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_1789860_6	1354722.JQLS01000008_gene3589	4.015e-52	188.0	COG0454@1|root,COG0456@2|Bacteria,1NFMI@1224|Proteobacteria,2VAUY@28211|Alphaproteobacteria,46QPV@74030|Roseovarius	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1789860_4	314264.ROS217_09215	1.36e-177	558.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria,46NKM@74030|Roseovarius	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
CMS1_k127_1789860_0	1288298.rosmuc_00348	1.888e-263	816.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,46NHC@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_1789860_2	391613.RTM1035_19226	7.16e-193	606.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,46PUJ@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS1_k127_1792779_6	314264.ROS217_23830	2.083e-16	87.0	2C73B@1|root,330Z7@2|Bacteria,1N6KX@1224|Proteobacteria,2V4HT@28211|Alphaproteobacteria,46NFK@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1792779_5	391613.RTM1035_15547	4.254e-29	123.0	2E7RH@1|root,3326U@2|Bacteria,1NC2F@1224|Proteobacteria,2UFKW@28211|Alphaproteobacteria,46R4N@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1405 Transcription initiation factor TFIIIB, Brf1 subunit Transcription initiation factor TFIIB	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1792779_1	1354722.JQLS01000008_gene600	2.729e-83	278.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,46Q02@74030|Roseovarius	28211|Alphaproteobacteria	S	CoA binding domain	yccU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS1_k127_1792779_4	1354722.JQLS01000008_gene1848	2.132e-37	149.0	2D05Y@1|root,32T7W@2|Bacteria,1RJF6@1224|Proteobacteria,2UA4X@28211|Alphaproteobacteria,46R40@74030|Roseovarius	28211|Alphaproteobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS1_k127_1792779_3	391613.RTM1035_11800	2.252e-47	176.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2UBU3@28211|Alphaproteobacteria,46QZP@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0140 Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
CMS1_k127_1792779_0	1288298.rosmuc_03271	1.902e-149	474.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria,46P5C@74030|Roseovarius	28211|Alphaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_1792779_2	314264.ROS217_21997	1.019e-60	212.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,2UBVK@28211|Alphaproteobacteria,46QNU@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	ccrB	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_1808490_17	1354722.JQLS01000008_gene170	1.739e-24	106.0	COG0715@1|root,COG0715@2|Bacteria,1MXA3@1224|Proteobacteria,2TQV6@28211|Alphaproteobacteria,46PAG@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	thiY	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_1808490_4	1354722.JQLS01000008_gene171	3.391e-164	527.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSP5@28211|Alphaproteobacteria,46P36@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_1808490_5	1354722.JQLS01000008_gene172	6.517e-162	516.0	COG0600@1|root,COG0600@2|Bacteria,1MUAR@1224|Proteobacteria,2TTED@28211|Alphaproteobacteria,46Q93@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_1808490_6	351016.RAZWK3B_06152	7.534e-153	484.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,2P1SZ@2433|Roseobacter	28211|Alphaproteobacteria	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	tauB	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS1_k127_1808490_0	89187.ISM_13615	9.335e-315	966.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,46NWF@74030|Roseovarius	28211|Alphaproteobacteria	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	dht	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
CMS1_k127_1808490_2	1122614.JHZF01000011_gene1611	1.092e-243	760.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2TR5X@28211|Alphaproteobacteria,2PD87@252301|Oceanicola	28211|Alphaproteobacteria	E	Peptidase family M20/M25/M40	amaB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_1808490_10	1354722.JQLS01000008_gene176	2.111e-101	332.0	COG1309@1|root,COG1309@2|Bacteria,1ND64@1224|Proteobacteria,2TTVA@28211|Alphaproteobacteria,46Q81@74030|Roseovarius	28211|Alphaproteobacteria	K	transcriptional regulator, TetR family	rutR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
CMS1_k127_1808490_1	391613.RTM1035_15442	8.349e-284	872.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,2TSPK@28211|Alphaproteobacteria,46P4K@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0167 Dihydroorotate dehydrogenase	preA	GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21,Fer4_4,Fer4_6
CMS1_k127_1808490_11	754035.Mesau_03356	2.213e-83	285.0	COG0500@1|root,COG2226@2|Bacteria,1RCDB@1224|Proteobacteria,2VF9E@28211|Alphaproteobacteria,43P6V@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1808490_3	1354722.JQLS01000008_gene188	1.515e-239	746.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,46PGS@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	preT	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS1_k127_1808490_7	1288298.rosmuc_02104	3.831e-145	462.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,2TV1R@28211|Alphaproteobacteria,46NK1@74030|Roseovarius	28211|Alphaproteobacteria	K	Pyruvate dehydrogenase complex repressor	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
CMS1_k127_1808490_13	351016.RAZWK3B_06202	1.188e-54	194.0	2AJ2R@1|root,319M2@2|Bacteria,1RJXB@1224|Proteobacteria,2UA6I@28211|Alphaproteobacteria,2P3HH@2433|Roseobacter	28211|Alphaproteobacteria	S	Conserved hypothetical protein (Lin0512_fam)	-	-	-	-	-	-	-	-	-	-	-	-	Lin0512_fam
CMS1_k127_1808490_12	391593.RCCS2_06679	2.145e-58	203.0	2DMD4@1|root,32NV5@2|Bacteria,1RI0E@1224|Proteobacteria,2UA1F@28211|Alphaproteobacteria,2P3E7@2433|Roseobacter	28211|Alphaproteobacteria	S	Conserved hypothetical protein (Lin0512_fam)	-	-	-	-	-	-	-	-	-	-	-	-	Lin0512_fam
CMS1_k127_1808490_9	351016.RAZWK3B_06222	4.391e-121	389.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,2TT92@28211|Alphaproteobacteria,2P15E@2433|Roseobacter	28211|Alphaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
CMS1_k127_1808490_8	1354722.JQLS01000008_gene183	1.007e-122	400.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2TSP3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM LrgB family protein	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
CMS1_k127_1808490_15	1354722.JQLS01000008_gene182	3.41e-45	166.0	COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,2UFFT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	effector of murein hydrolase LrgA	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
CMS1_k127_1808490_16	351016.RAZWK3B_06237	7.984e-43	161.0	2E6BA@1|root,330Z4@2|Bacteria,1NEDW@1224|Proteobacteria,2UGDW@28211|Alphaproteobacteria,2P3QJ@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1808490_14	314264.ROS217_08034	2.904e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,1N1SU@1224|Proteobacteria,2UA9R@28211|Alphaproteobacteria,46R7B@74030|Roseovarius	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_1825655_2	1288298.rosmuc_02626	2.636e-73	252.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,46P5G@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_1825655_0	314264.ROS217_16070	0.0	1257.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,46PNJ@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_1825655_1	391613.RTM1035_15607	2.774e-194	609.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,46PHY@74030|Roseovarius	28211|Alphaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS1_k127_1826653_9	1461694.ATO9_17015	2.177e-117	380.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,2PCKC@252301|Oceanicola	28211|Alphaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS1_k127_1826653_7	1354722.JQLS01000008_gene1392	2.739e-125	403.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,46PDM@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF502)	MA20_12960	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS1_k127_1826653_5	89187.ISM_15675	2.395e-139	448.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,46PFM@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS1_k127_1826653_0	1288298.rosmuc_01592	0.0	1035.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,46PZC@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	nikA	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS1_k127_1826653_13	1288298.rosmuc_01591	2.488e-14	74.0	2AJVT@1|root,31AIJ@2|Bacteria,1Q5QF@1224|Proteobacteria,2VC1D@28211|Alphaproteobacteria,46S2C@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1826653_3	1354722.JQLS01000008_gene1396	3.645e-189	594.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,46Q88@74030|Roseovarius	28211|Alphaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS1_k127_1826653_6	1354722.JQLS01000008_gene1397	2.847e-139	446.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,46PSB@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS1_k127_1826653_4	1288298.rosmuc_01588	9.215e-144	461.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,46P6I@74030|Roseovarius	28211|Alphaproteobacteria	Q	involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_1826653_11	1415756.JQMY01000001_gene2760	7.627e-57	203.0	COG2995@1|root,COG2995@2|Bacteria,1REAG@1224|Proteobacteria,2U7KC@28211|Alphaproteobacteria,2PEEX@252301|Oceanicola	28211|Alphaproteobacteria	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
CMS1_k127_1826653_8	391613.RTM1035_08274	4.4e-119	387.0	28M53@1|root,2ZAIY@2|Bacteria,1R9K6@1224|Proteobacteria,2TT4F@28211|Alphaproteobacteria,46PQZ@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1196 Chromosome segregation ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1826653_2	1288298.rosmuc_01584	1.443e-268	831.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,46PT2@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS1_k127_1826653_10	351016.RAZWK3B_17513	1.066e-94	312.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2TUVR@28211|Alphaproteobacteria,2P2ZV@2433|Roseobacter	28211|Alphaproteobacteria	S	membrane protein, required for colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS1_k127_1826653_12	1354722.JQLS01000008_gene1403	3.494e-51	185.0	COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,2UFXH@28211|Alphaproteobacteria,46QSC@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
CMS1_k127_1826653_1	391613.RTM1035_08294	5.618e-297	912.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2TR8V@28211|Alphaproteobacteria,46NEA@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS1_k127_1853711_5	391613.RTM1035_13298	9.929e-52	183.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,46PAC@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0513 Superfamily II DNA and RNA helicases	mgpS	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
CMS1_k127_1853711_4	314264.ROS217_03590	1.089e-80	273.0	COG0457@1|root,COG0457@2|Bacteria,1N0DE@1224|Proteobacteria,2UCGA@28211|Alphaproteobacteria,46PNU@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	MA20_05980	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_1853711_6	89187.ISM_00040	4.098e-39	147.0	COG3255@1|root,COG3255@2|Bacteria,1N0RD@1224|Proteobacteria,2UBXK@28211|Alphaproteobacteria,46QZT@74030|Roseovarius	28211|Alphaproteobacteria	I	sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_1853711_1	391613.RTM1035_13313	1.612e-172	546.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria,46NRM@74030|Roseovarius	28211|Alphaproteobacteria	I	hydrolase, alpha beta fold family protein	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
CMS1_k127_1853711_0	1354722.JQLS01000008_gene571	0.0	1148.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2TRPY@28211|Alphaproteobacteria,46Q25@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1164 Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS1_k127_1853711_2	1354722.JQLS01000008_gene569	1.246e-160	513.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,2TTCR@28211|Alphaproteobacteria,46N9K@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
CMS1_k127_1853711_3	1288298.rosmuc_01967	1.227e-151	481.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,46QA4@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70 sigma32)	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
CMS1_k127_1859856_1	1354722.JQLS01000008_gene1900	9.851e-197	614.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,46NZJ@74030|Roseovarius	28211|Alphaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_1859856_0	314264.ROS217_16296	0.0	1089.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,46PN8@74030|Roseovarius	28211|Alphaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS1_k127_1863537_1	1354722.JQLS01000008_gene1857	8.132e-251	778.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2TS6R@28211|Alphaproteobacteria,46Q85@74030|Roseovarius	28211|Alphaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS1_k127_1863537_4	1288298.rosmuc_03251	1.214e-181	575.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2TUSP@28211|Alphaproteobacteria,46Q53@74030|Roseovarius	28211|Alphaproteobacteria	D	COG4942 Membrane-bound metallopeptidase	filA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_1863537_2	1354722.JQLS01000008_gene1855	1.879e-249	773.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,46QCU@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS1_k127_1863537_7	1354722.JQLS01000008_gene1854	1.559e-95	316.0	2BZ3T@1|root,315W2@2|Bacteria,1PV8U@1224|Proteobacteria,2U9KU@28211|Alphaproteobacteria,46QJN@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1863537_10	1305735.JAFT01000005_gene727	4.456e-12	70.0	2AJD5@1|root,319YN@2|Bacteria,1Q4GF@1224|Proteobacteria,2VAYM@28211|Alphaproteobacteria,2PEVZ@252301|Oceanicola	28211|Alphaproteobacteria	S	Bacterial aa3 type cytochrome c oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro_2
CMS1_k127_1863537_8	1354722.JQLS01000008_gene1852	1.033e-68	241.0	292H0@1|root,2ZQ15@2|Bacteria,1RETR@1224|Proteobacteria,2U83Y@28211|Alphaproteobacteria,46QQP@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1863537_3	1354722.JQLS01000008_gene1851	1.116e-186	594.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2TSYY@28211|Alphaproteobacteria,46QC8@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_1863537_0	314264.ROS217_22022	0.0	1030.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,46PWQ@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS1_k127_1863537_5	314264.ROS217_22017	1.688e-141	455.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,46NER@74030|Roseovarius	28211|Alphaproteobacteria	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS1_k127_1863537_9	1354722.JQLS01000008_gene1943	2.45e-54	193.0	COG4392@1|root,COG4392@2|Bacteria,1MZUZ@1224|Proteobacteria,2UC31@28211|Alphaproteobacteria,46R2J@74030|Roseovarius	28211|Alphaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
CMS1_k127_1863537_6	391613.RTM1035_12008	1.261e-129	416.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,2TVIA@28211|Alphaproteobacteria,46NSK@74030|Roseovarius	28211|Alphaproteobacteria	E	branched-chain amino acid permease (azaleucine resistance)	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
CMS1_k127_1863687_0	1354722.JQLS01000008_gene1626	2.22e-146	469.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,46QDN@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_1863687_1	1354722.JQLS01000008_gene1625	1.357e-106	349.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2TW9J@28211|Alphaproteobacteria,46P9U@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	envZ	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_1877124_3	999611.KI421504_gene2039	1.296e-89	297.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2TSYI@28211|Alphaproteobacteria,27ZNI@191028|Leisingera	28211|Alphaproteobacteria	P	Phosphate transporter family	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS1_k127_1877124_0	1415756.JQMY01000001_gene3578	5.387e-197	618.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2TQQ2@28211|Alphaproteobacteria,2PC80@252301|Oceanicola	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	mch	GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
CMS1_k127_1877124_4	391613.RTM1035_16307	1.199e-33	132.0	COG5515@1|root,COG5515@2|Bacteria,1N87I@1224|Proteobacteria,2UF35@28211|Alphaproteobacteria,46R88@74030|Roseovarius	28211|Alphaproteobacteria	S	conserved small protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1737
CMS1_k127_1877124_2	351016.RAZWK3B_04050	3.191e-90	299.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,2TQWY@28211|Alphaproteobacteria,2P2VM@2433|Roseobacter	28211|Alphaproteobacteria	S	NnrU protein	nnrU	-	-	-	-	-	-	-	-	-	-	-	NnrU
CMS1_k127_1877124_1	1354722.JQLS01000008_gene107	1.841e-124	400.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,46Q75@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	3.1.2.30,4.1.3.34	ko:K01644,ko:K14451	ko00630,ko01120,ko01200,ko02020,map00630,map01120,map01200,map02020	M00373	R00362,R10612	RC00004,RC00014,RC00067,RC01118	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_1899791_2	1288298.rosmuc_01923	1.975e-40	153.0	COG4160@1|root,COG4160@2|Bacteria,1N189@1224|Proteobacteria,2TSWV@28211|Alphaproteobacteria,46PJA@74030|Roseovarius	28211|Alphaproteobacteria	P	Polar amino acid uptake family ABC transporter, permease protein	occM	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_1899791_0	391613.RTM1035_13668	1.233e-139	445.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,2U1NX@28211|Alphaproteobacteria,46NKT@74030|Roseovarius	28211|Alphaproteobacteria	P	Polar amino acid uptake family ABC transporter, permease protein	hisQ	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_1899791_1	1288298.rosmuc_01925	3.465e-111	361.0	COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,2TU1I@28211|Alphaproteobacteria,46P1M@74030|Roseovarius	28211|Alphaproteobacteria	ET	Polar amino acid uptake family ABC transporter, periplasmic substrate-binding protein	hisJ	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_1903153_1	1354722.JQLS01000008_gene160	0.0	1077.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,46NFD@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CMS1_k127_1903153_6	1354722.JQLS01000008_gene159	3.856e-148	473.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,46N9Q@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_1903153_7	351016.RAZWK3B_06077	2.117e-140	447.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2TV0E@28211|Alphaproteobacteria,2P157@2433|Roseobacter	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	fnrL	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
CMS1_k127_1903153_3	1354722.JQLS01000008_gene157	4.154e-251	779.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2TRKT@28211|Alphaproteobacteria,46N94@74030|Roseovarius	28211|Alphaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_1903153_2	1288298.rosmuc_02241	1.772e-288	891.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,46NJU@74030|Roseovarius	28211|Alphaproteobacteria	P	Oligopeptide dipeptide uptake family ABC transporter, ATP-binding protein	yejF	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02031,ko:K02032,ko:K13892,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00348,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
CMS1_k127_1903153_4	1288298.rosmuc_02240	2.042e-223	694.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,46PUA@74030|Roseovarius	28211|Alphaproteobacteria	P	Oligopeptide dipeptide uptake family ABC transporter, permease protein	yejE	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
CMS1_k127_1903153_5	391613.RTM1035_01430	2.986e-215	670.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2TQJD@28211|Alphaproteobacteria,46NR4@74030|Roseovarius	28211|Alphaproteobacteria	P	transport system, permease component	yejB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
CMS1_k127_1903153_0	314264.ROS217_12186	0.0	1169.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,46PHH@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	yejA	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS1_k127_1903153_8	314264.ROS217_12181	5.976e-130	421.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,46PGR@74030|Roseovarius	28211|Alphaproteobacteria	C	COG3474 Cytochrome c2	cycM	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_1911987_3	1354722.JQLS01000008_gene597	4.251e-115	372.0	2CKJA@1|root,2Z7YS@2|Bacteria,1NBXM@1224|Proteobacteria,2TV3D@28211|Alphaproteobacteria,46PNK@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1911987_4	314264.ROS217_15570	2.572e-74	255.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,46QQ5@74030|Roseovarius	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_1911987_0	1288298.rosmuc_02015	1.322e-262	811.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2TQW9@28211|Alphaproteobacteria,46NZS@74030|Roseovarius	28211|Alphaproteobacteria	E	O-acetylhomoserine sulfhydrylase	metY	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47,2.5.1.49	ko:K01738,ko:K01740	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R01287,R03601,R04859	RC00020,RC02814,RC02821,RC02848	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_1911987_2	1354722.JQLS01000008_gene2147	2.301e-236	753.0	2C40D@1|root,2Z7MY@2|Bacteria,1MUQA@1224|Proteobacteria,2TTM7@28211|Alphaproteobacteria,46QK1@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1911987_1	1354722.JQLS01000008_gene2148	1.693e-246	768.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,46Q4I@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_1918762_2	1288298.rosmuc_00143	6.757e-94	319.0	COG4223@1|root,COG4223@2|Bacteria,1RHEC@1224|Proteobacteria,2UAF8@28211|Alphaproteobacteria,46QEN@74030|Roseovarius	28211|Alphaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	Mitofilin
CMS1_k127_1918762_3	1354722.JQLS01000008_gene3218	5.154e-86	291.0	COG1587@1|root,COG1587@2|Bacteria,1MZCJ@1224|Proteobacteria,2UC6J@28211|Alphaproteobacteria,46NWA@74030|Roseovarius	28211|Alphaproteobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS1_k127_1918762_0	1354722.JQLS01000008_gene3219	8.333e-195	612.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2TSF7@28211|Alphaproteobacteria,46NWI@74030|Roseovarius	28211|Alphaproteobacteria	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_1918762_1	1288298.rosmuc_00146	2.31e-99	327.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,46P09@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0240 Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS1_k127_193032_9	1208323.B30_16118	5.681e-64	224.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2UBZM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
CMS1_k127_193032_7	1121271.AUCM01000019_gene509	1.168e-111	364.0	COG0212@1|root,COG0212@2|Bacteria,1RAZI@1224|Proteobacteria,2U6UH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	5-FTHF_cyc-lig
CMS1_k127_193032_8	1208323.B30_16108	2.016e-77	263.0	COG3154@1|root,COG3154@2|Bacteria,1RH2M@1224|Proteobacteria,2UA8H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	lipid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_193032_1	1208323.B30_16103	2.153e-200	625.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2TS5M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Peptidase U32	yhbU	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CMS1_k127_193032_3	1123360.thalar_02876	1.206e-159	508.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2TSF0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PFAM peptidase U32	yhbV	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
CMS1_k127_193032_0	314264.ROS217_20942	6.738e-217	688.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46Q92@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
CMS1_k127_193032_10	1354722.JQLS01000008_gene1277	1.956e-61	217.0	COG2068@1|root,COG2068@2|Bacteria,1RH9W@1224|Proteobacteria,2U9V3@28211|Alphaproteobacteria,46P4Q@74030|Roseovarius	28211|Alphaproteobacteria	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS1_k127_193032_4	314264.ROS217_19427	2.851e-153	486.0	COG0765@1|root,COG0765@2|Bacteria,1QV7F@1224|Proteobacteria,2TUYT@28211|Alphaproteobacteria,46PJ4@74030|Roseovarius	28211|Alphaproteobacteria	P	His Glu Gln Arg opine family ABC transporter, permease protein	hisM	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_193032_2	1288298.rosmuc_01403	2.131e-176	555.0	COG4215@1|root,COG4215@2|Bacteria,1NH6Q@1224|Proteobacteria,2U09N@28211|Alphaproteobacteria,46P5R@74030|Roseovarius	28211|Alphaproteobacteria	P	COG4215 ABC-type arginine transport system, permease component	artQ	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_193032_6	1288298.rosmuc_01404	1.415e-133	428.0	COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,2TV6I@28211|Alphaproteobacteria,46Q8U@74030|Roseovarius	28211|Alphaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_193032_5	391613.RTM1035_09189	2.997e-149	474.0	COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,2TVZC@28211|Alphaproteobacteria,46NZ1@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4598 ABC-type histidine transport system, ATPase component	occP	-	3.6.3.21	ko:K02028,ko:K10021,ko:K10025	ko02010,map02010	M00231,M00235,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.11,3.A.1.3.5,3.A.1.3.6	-	-	ABC_tran
CMS1_k127_193032_11	391613.RTM1035_09184	3.476e-06	48.0	COG3221@1|root,COG3221@2|Bacteria,1R6YE@1224|Proteobacteria,2U6QH@28211|Alphaproteobacteria,46NAU@74030|Roseovarius	28211|Alphaproteobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
CMS1_k127_1979184_8	1354722.JQLS01000008_gene815	7.544e-33	129.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,46PB3@74030|Roseovarius	28211|Alphaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_1979184_5	1354722.JQLS01000008_gene816	6.339e-148	474.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,46RK6@74030|Roseovarius	28211|Alphaproteobacteria	M	UDP-3-O-acyl N-acetylglycosamine deacetylase	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
CMS1_k127_1979184_4	1354722.JQLS01000008_gene817	3.194e-161	510.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,46PIF@74030|Roseovarius	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS1_k127_1979184_2	1354722.JQLS01000008_gene818	6.926e-267	830.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria,46NKA@74030|Roseovarius	28211|Alphaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CMS1_k127_1979184_9	981327.F925_02277	1.781e-24	107.0	COG1403@1|root,COG1403@2|Bacteria,1NCV0@1224|Proteobacteria,1SEPH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_1979184_3	1354722.JQLS01000008_gene819	3.29e-245	762.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,46NE0@74030|Roseovarius	28211|Alphaproteobacteria	C	D-lactate dehydrogenase (Cytochrome), FAD	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_1979184_0	391613.RTM1035_04955	2.514e-296	916.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2TTBG@28211|Alphaproteobacteria,46PRF@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0038 Chloride channel protein EriC	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
CMS1_k127_1979184_6	1354722.JQLS01000008_gene821	3.675e-54	191.0	COG2343@1|root,COG2343@2|Bacteria,1RHXD@1224|Proteobacteria,2UC5N@28211|Alphaproteobacteria,46QUZ@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS1_k127_1979184_1	351016.RAZWK3B_13154	1.9e-277	864.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,2P1ZF@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0006 Xaa-Pro aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
CMS1_k127_1979184_7	391613.RTM1035_04970	1.058e-49	177.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,46NNE@74030|Roseovarius	28211|Alphaproteobacteria	H	Cobalt chelatase, pCobT subunit	cobT	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
CMS1_k127_1991807_4	1288298.rosmuc_00864	5.547e-68	232.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,46QZC@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	sdhC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_1991807_5	1288298.rosmuc_00863	1.625e-56	199.0	COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2UC3G@28211|Alphaproteobacteria,46QX3@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_1991807_1	351016.RAZWK3B_04085	0.0	1139.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,2P1ZI@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_1991807_6	1354722.JQLS01000008_gene3755	2.363e-38	147.0	2CVUM@1|root,32SYC@2|Bacteria,1N58V@1224|Proteobacteria,2UEME@28211|Alphaproteobacteria,46R0H@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1991807_2	981384.AEYW01000021_gene3420	3.993e-175	548.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,4NAH4@97050|Ruegeria	28211|Alphaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_17,Fer4_8
CMS1_k127_1991807_8	314264.ROS217_08374	1.918e-07	55.0	2AD2X@1|root,312R6@2|Bacteria,1PR3I@1224|Proteobacteria,2V3EY@28211|Alphaproteobacteria,46RC8@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1991807_7	1354722.JQLS01000008_gene3750	3.163e-26	108.0	2EI6K@1|root,33BXX@2|Bacteria,1NJ7V@1224|Proteobacteria,2UK16@28211|Alphaproteobacteria,46R5I@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1991807_3	1354722.JQLS01000008_gene3749	8.989e-164	518.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TSFM@28211|Alphaproteobacteria,46PBZ@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
CMS1_k127_1991807_0	89187.ISM_07190	0.0	1501.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,46NCT@74030|Roseovarius	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_2003326_1	1354722.JQLS01000008_gene796	1.405e-47	174.0	2E802@1|root,332ED@2|Bacteria,1N94X@1224|Proteobacteria,2UFU6@28211|Alphaproteobacteria,46QZF@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2003326_2	1354722.JQLS01000008_gene795	1.313e-40	153.0	COG1917@1|root,COG1917@2|Bacteria,1N7MR@1224|Proteobacteria,2UFI3@28211|Alphaproteobacteria,46R2I@74030|Roseovarius	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2003326_0	1288298.rosmuc_02055	0.0	1002.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,46NQJ@74030|Roseovarius	28211|Alphaproteobacteria	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_2003326_3	391613.RTM1035_12898	6.179e-27	111.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRQD@28211|Alphaproteobacteria,46Q8D@74030|Roseovarius	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	MA20_01870	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1,Sugar_tr
CMS1_k127_2008230_4	314264.ROS217_18592	1.502e-65	230.0	COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,2U9BM@28211|Alphaproteobacteria,46QS0@74030|Roseovarius	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	MA20_36950	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_2008230_1	314264.ROS217_18587	9.537e-143	457.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2TTMB@28211|Alphaproteobacteria,46NCQ@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_2008230_0	351016.RAZWK3B_15588	1.17e-264	820.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,2TR6M@28211|Alphaproteobacteria,2P1WW@2433|Roseobacter	28211|Alphaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
CMS1_k127_2008230_2	351016.RAZWK3B_15583	4.389e-142	454.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,2P1RM@2433|Roseobacter	28211|Alphaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_2008230_5	391613.RTM1035_07258	7.924e-65	223.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2UCKH@28211|Alphaproteobacteria,46QUD@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
CMS1_k127_2008230_3	391613.RTM1035_07253	1.789e-82	276.0	COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria,46NQH@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0822 NifU homolog involved in Fe-S cluster formation	nifU	-	-	-	-	-	-	-	-	-	-	-	NifU_N
CMS1_k127_2037239_0	391613.RTM1035_18640	4.999e-139	442.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U1QF@28211|Alphaproteobacteria,46PWA@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_2037239_2	391613.RTM1035_18635	2.268e-57	202.0	COG2009@1|root,COG2009@2|Bacteria,1MZMK@1224|Proteobacteria,2VGK2@28211|Alphaproteobacteria,46QWV@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	-	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_2037239_3	935848.JAEN01000018_gene421	2.824e-30	123.0	COG2142@1|root,COG2142@2|Bacteria,1MZKE@1224|Proteobacteria,2UDDU@28211|Alphaproteobacteria,2PYU4@265|Paracoccus	28211|Alphaproteobacteria	C	succinate dehydrogenase	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_2037239_1	314264.ROS217_09605	8.535e-104	339.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U08R@28211|Alphaproteobacteria,46Q89@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit	frdB	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
CMS1_k127_203772_0	102129.Lepto7375DRAFT_4624	5.817e-219	681.0	COG1062@1|root,COG1062@2|Bacteria,1G2S4@1117|Cyanobacteria,1H7TD@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	frmA	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_203772_1	1144275.COCOR_07000	1.479e-124	404.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS1_k127_2055150_1	1288298.rosmuc_00322	2.737e-203	636.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,46QAV@74030|Roseovarius	28211|Alphaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_2055150_6	1288298.rosmuc_00321	7.056e-52	184.0	2C3PV@1|root,3307H@2|Bacteria,1N0Y3@1224|Proteobacteria,2UC7H@28211|Alphaproteobacteria,46R1A@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2834)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2834
CMS1_k127_2055150_7	314264.ROS217_08650	4.286e-05	49.0	2AQR6@1|root,31FYX@2|Bacteria,1QDR2@1224|Proteobacteria,2V3G9@28211|Alphaproteobacteria,46RCI@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2055150_0	1288298.rosmuc_00319	1.54e-269	846.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,46PMZ@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0165 Argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_2055150_4	1354722.JQLS01000008_gene3687	9.645e-97	321.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,46PK4@74030|Roseovarius	28211|Alphaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	tlpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_2055150_3	1354722.JQLS01000008_gene3686	8.34e-181	567.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2TRDH@28211|Alphaproteobacteria,46NI1@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
CMS1_k127_2055150_2	314264.ROS217_08675	3.036e-192	612.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,46PG3@74030|Roseovarius	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CMS1_k127_2055150_5	314264.ROS217_08680	1.973e-74	253.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,46NW5@74030|Roseovarius	28211|Alphaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS1_k127_2065663_6	314264.ROS217_15460	7.151e-10	59.0	COG0679@1|root,COG0679@2|Bacteria,1MY23@1224|Proteobacteria,2TR4M@28211|Alphaproteobacteria,46NVI@74030|Roseovarius	28211|Alphaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS1_k127_2065663_2	1288298.rosmuc_02868	4.629e-159	507.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,46PGH@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS1_k127_2065663_3	1354722.JQLS01000008_gene2171	8.949e-146	467.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,46PMW@74030|Roseovarius	28211|Alphaproteobacteria	L	Hydrolase, TatD family protein	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS1_k127_2065663_1	1354722.JQLS01000008_gene2172	3.106e-195	614.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,46QA7@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
CMS1_k127_2065663_4	1354722.JQLS01000008_gene2173	3.171e-99	329.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,46PXM@74030|Roseovarius	28211|Alphaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS1_k127_2065663_0	1354722.JQLS01000008_gene2174	1.523e-201	632.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,46NNS@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
CMS1_k127_2065663_5	391613.RTM1035_04720	3.467e-48	175.0	COG3087@1|root,COG3087@2|Bacteria,1NC8R@1224|Proteobacteria,2TUYG@28211|Alphaproteobacteria,46Q43@74030|Roseovarius	28211|Alphaproteobacteria	D	COG3087 Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_2075525_0	1354722.JQLS01000008_gene2174	8.656e-204	640.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,46NNS@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
CMS1_k127_2075525_1	391613.RTM1035_04720	2.871e-47	172.0	COG3087@1|root,COG3087@2|Bacteria,1NC8R@1224|Proteobacteria,2TUYG@28211|Alphaproteobacteria,46Q43@74030|Roseovarius	28211|Alphaproteobacteria	D	COG3087 Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_2080294_0	1354722.JQLS01000008_gene2992	3.031e-303	942.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,46PN4@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
CMS1_k127_2080294_3	1354722.JQLS01000008_gene3047	2.336e-175	557.0	COG4313@1|root,COG4313@2|Bacteria,1MXNW@1224|Proteobacteria,2TV0V@28211|Alphaproteobacteria,46NMS@74030|Roseovarius	28211|Alphaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,Phenol_MetA_deg
CMS1_k127_2080294_4	351016.RAZWK3B_05042	6.332e-159	505.0	COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2TU7N@28211|Alphaproteobacteria,2P2N2@2433|Roseobacter	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	sam	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_2080294_6	391613.RTM1035_15462	6.147e-115	377.0	COG4121@1|root,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2TUNX@28211|Alphaproteobacteria,46NYG@74030|Roseovarius	28211|Alphaproteobacteria	J	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
CMS1_k127_2080294_5	314264.ROS217_06780	1.551e-156	502.0	COG0665@1|root,COG0665@2|Bacteria,1MUUJ@1224|Proteobacteria,2TR9J@28211|Alphaproteobacteria,46QB4@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	goxB	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_2080294_8	1354722.JQLS01000008_gene2898	2.076e-56	200.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2U9J3@28211|Alphaproteobacteria,46QTE@74030|Roseovarius	28211|Alphaproteobacteria	E	And related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_2080294_1	1288298.rosmuc_02132	3.775e-283	875.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,46PKH@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2080294_2	1354722.JQLS01000008_gene2869	1.21e-215	674.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2TSSE@28211|Alphaproteobacteria,46NRS@74030|Roseovarius	28211|Alphaproteobacteria	G	Malonyl-CoA decarboxylase N-terminal domain	matA	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
CMS1_k127_2080294_7	89187.ISM_04325	3.179e-99	325.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,46P6C@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	MA20_30170	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_208931_1	1288298.rosmuc_00680	2.978e-78	262.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,46NM5@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_208931_0	1354722.JQLS01000008_gene97	1.032e-283	874.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,46PYN@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_208931_2	1354722.JQLS01000008_gene98	1.448e-56	201.0	COG3686@1|root,COG3686@2|Bacteria,1N00R@1224|Proteobacteria,2U94Y@28211|Alphaproteobacteria,46QZ5@74030|Roseovarius	28211|Alphaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_208931_3	391593.RCCS2_13144	3.371e-21	92.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2P181@2433|Roseobacter	28211|Alphaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_2089633_2	1354722.JQLS01000008_gene1071	1.946e-104	340.0	COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria,46PXJ@74030|Roseovarius	28211|Alphaproteobacteria	S	phage phi-C31 gp36 major capsid-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
CMS1_k127_2089633_1	1354722.JQLS01000008_gene1072	2.841e-105	344.0	2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,46Q9G@74030|Roseovarius	28211|Alphaproteobacteria	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
CMS1_k127_2089633_7	351016.RAZWK3B_17718	9.586e-37	142.0	COG5614@1|root,COG5614@2|Bacteria,1N0CB@1224|Proteobacteria,2UBY8@28211|Alphaproteobacteria,2P3KC@2433|Roseobacter	28211|Alphaproteobacteria	S	Phage head-tail joining protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_H_T_join
CMS1_k127_2089633_5	1354722.JQLS01000008_gene1074	4.759e-52	190.0	2DE8C@1|root,32U2V@2|Bacteria,1MZH7@1224|Proteobacteria,2UBWF@28211|Alphaproteobacteria,46QV6@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3168)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3168
CMS1_k127_2089633_3	391613.RTM1035_10705	3.904e-77	259.0	COG5437@1|root,COG5437@2|Bacteria,1RH1Z@1224|Proteobacteria,2U9I4@28211|Alphaproteobacteria,46QQR@74030|Roseovarius	28211|Alphaproteobacteria	S	Major tail protein, TP901-1	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_2
CMS1_k127_2089633_6	391613.RTM1035_10700	7.099e-48	173.0	2CN1W@1|root,32SG3@2|Bacteria,1N0IV@1224|Proteobacteria,2UC9F@28211|Alphaproteobacteria,46R2N@74030|Roseovarius	28211|Alphaproteobacteria	S	Phage tail tube protein, GTA-gp10	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_11
CMS1_k127_2089633_8	1530186.JQEY01000003_gene2329	1.092e-22	98.0	2E2Z2@1|root,32XZR@2|Bacteria,1NA9J@1224|Proteobacteria,2UFQ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage tail assembly chaperone protein, TAC	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_6
CMS1_k127_2089633_0	1288298.rosmuc_03455	2.45e-109	356.0	COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,46QA2@74030|Roseovarius	28211|Alphaproteobacteria	S	COG5281 Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2089633_4	1354722.JQLS01000008_gene1079	3.242e-73	247.0	COG5448@1|root,COG5448@2|Bacteria,1MXM8@1224|Proteobacteria,2TTJ3@28211|Alphaproteobacteria,46QIK@74030|Roseovarius	28211|Alphaproteobacteria	S	Conserved hypothetical protein 2217 (DUF2460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
CMS1_k127_2105251_5	439496.RBY4I_3833	1.021e-47	174.0	COG4177@1|root,COG4177@2|Bacteria,1MXPG@1224|Proteobacteria,2VFF4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_2105251_3	351016.RAZWK3B_08034	3.38e-155	493.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2105251_1	999549.KI421513_gene2009	5.115e-255	790.0	COG0683@1|root,COG0683@2|Bacteria,1MW99@1224|Proteobacteria,2V88K@28211|Alphaproteobacteria,27ZS1@191028|Leisingera	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_2105251_4	351016.RAZWK3B_08024	5.078e-120	390.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2U67X@28211|Alphaproteobacteria,2P3U6@2433|Roseobacter	28211|Alphaproteobacteria	K	COG2186 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_2105251_2	351016.RAZWK3B_08019	3.847e-228	713.0	COG0683@1|root,COG0683@2|Bacteria,1MW99@1224|Proteobacteria,2TTIC@28211|Alphaproteobacteria,2P4EW@2433|Roseobacter	28211|Alphaproteobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_2105251_0	351016.RAZWK3B_08014	2.091e-255	792.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TTY2@28211|Alphaproteobacteria,2P0ZJ@2433|Roseobacter	28211|Alphaproteobacteria	C	flavoprotein involved in K transport	-	-	1.14.13.148	ko:K18277	ko00680,map00680	-	R05623	RC00058	ko00000,ko00001,ko01000	-	-	-	FMO-like
CMS1_k127_2108611_1	1288298.rosmuc_02912	8.823e-278	859.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46NWW@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	dhaS	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_2108611_3	1354722.JQLS01000008_gene2123	6.1e-74	252.0	COG1853@1|root,COG1853@2|Bacteria,1NESS@1224|Proteobacteria,2UHYR@28211|Alphaproteobacteria,46PNC@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_2108611_2	351016.RAZWK3B_13859	6.442e-158	500.0	COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,2U1U3@28211|Alphaproteobacteria,2P3Q0@2433|Roseobacter	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_2108611_0	1354722.JQLS01000008_gene1349	8.806e-282	874.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,46PSY@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_2108611_5	1121948.AUAC01000003_gene2837	3.334e-37	150.0	COG0666@1|root,COG0666@2|Bacteria,1NC5F@1224|Proteobacteria,2UNCX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0666 FOG Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
CMS1_k127_2108611_4	1445613.JALM01000015_gene5634	9.361e-51	186.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,4E82M@85010|Pseudonocardiales	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS1_k127_2110154_9	1121479.AUBS01000004_gene2572	2.899e-10	61.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	HNH endonuclease	MA20_20605	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS1_k127_2110154_1	314264.ROS217_23750	0.0	1039.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,46P49@74030|Roseovarius	28211|Alphaproteobacteria	V	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	atm1	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2110154_4	314264.ROS217_23755	6.916e-112	375.0	COG1652@1|root,COG1652@2|Bacteria,1MWMR@1224|Proteobacteria,2U7UH@28211|Alphaproteobacteria,46NET@74030|Roseovarius	28211|Alphaproteobacteria	S	protein containing LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_2110154_5	1461694.ATO9_09215	3.148e-77	266.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,2PDXE@252301|Oceanicola	28211|Alphaproteobacteria	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_2110154_2	314264.ROS217_23765	6.792e-157	498.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2TV8D@28211|Alphaproteobacteria,46QFX@74030|Roseovarius	28211|Alphaproteobacteria	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
CMS1_k127_2110154_3	1288298.rosmuc_02035	9.076e-126	402.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,46NNX@74030|Roseovarius	28211|Alphaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS1_k127_2110154_7	999550.KI421507_gene1182	2.365e-52	192.0	COG4583@1|root,COG4583@2|Bacteria,1N27A@1224|Proteobacteria,2U77J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Sarcosine oxidase, gamma subunit	soxG	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
CMS1_k127_2110154_0	1354722.JQLS01000008_gene2039	0.0	1807.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,46P1Q@74030|Roseovarius	28211|Alphaproteobacteria	C	Sarcosine oxidase, alpha subunit family protein	soxA	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_2110154_6	1354722.JQLS01000008_gene2040	1.137e-66	227.0	COG4311@1|root,COG4311@2|Bacteria,1MZC3@1224|Proteobacteria,2UC8C@28211|Alphaproteobacteria,46QZ1@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4311 Sarcosine oxidase delta subunit	soxD	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
CMS1_k127_2110154_8	391613.RTM1035_13013	9.308e-11	61.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,46QGJ@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	soxB3	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_2122885_2	766499.C357_16126	2.259e-62	216.0	COG0410@1|root,COG0410@2|Bacteria,1R5HF@1224|Proteobacteria,2TV1S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_2122885_0	314264.ROS217_06034	7.83e-237	739.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46PAI@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_2122885_1	1288298.rosmuc_00611	1.647e-102	338.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,46P0K@74030|Roseovarius	28211|Alphaproteobacteria	IQ	related to short-chain alcohol dehydrogenases	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_215270_9	314264.ROS217_08349	1.814e-09	62.0	2AJGM@1|root,31A32@2|Bacteria,1Q4TT@1224|Proteobacteria,2VB8U@28211|Alphaproteobacteria,46R8K@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_215270_3	1288298.rosmuc_00038	9.319e-124	400.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,46Q98@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS1_k127_215270_4	1317124.DW2_02989	3.516e-78	271.0	COG2374@1|root,COG2374@2|Bacteria,1R7ET@1224|Proteobacteria,2U4P5@28211|Alphaproteobacteria,2XP7J@285107|Thioclava	28211|Alphaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_215270_0	391616.OA238_c34260	0.0	1289.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2TTSC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional accessory protein	tex	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CMS1_k127_215270_6	391613.RTM1035_11190	2.613e-57	203.0	2F35G@1|root,33W04@2|Bacteria,1NWGB@1224|Proteobacteria,2USAG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_215270_1	1288298.rosmuc_02764	3.118e-258	802.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,46QMR@74030|Roseovarius	28211|Alphaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS1_k127_215270_8	1288298.rosmuc_02765	3.444e-46	172.0	arCOG11477@1|root,32TJG@2|Bacteria,1MYXX@1224|Proteobacteria,2U9X3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS1_k127_215270_5	391589.RGAI101_2922	1.239e-72	250.0	28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,2TVJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_215270_2	314264.ROS217_03650	2.066e-210	658.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,46NEB@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0031 Cysteine synthase	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_215270_7	1354722.JQLS01000005_gene3949	2.005e-51	184.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,46QK0@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS1_k127_2154648_4	1354722.JQLS01000008_gene2092	5.067e-23	98.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,46NH6@74030|Roseovarius	28211|Alphaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS1_k127_2154648_0	351016.RAZWK3B_01630	5.212e-152	489.0	COG0025@1|root,COG0025@2|Bacteria,1QTW8@1224|Proteobacteria,2U0BC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_2154648_1	314264.ROS217_22077	3.353e-126	405.0	COG1802@1|root,COG1802@2|Bacteria,1MVXM@1224|Proteobacteria,2TT9E@28211|Alphaproteobacteria,46NXN@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, GntR family	mcbR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_2154648_2	314264.ROS217_22082	7.026e-110	359.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,46NPN@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function DUF45	MA20_23375	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CMS1_k127_2154648_3	1354722.JQLS01000008_gene1864	6.848e-46	167.0	COG4530@1|root,COG4530@2|Bacteria,1N85Z@1224|Proteobacteria,2UF7V@28211|Alphaproteobacteria,46QV9@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (FYDLN_acid)	MA20_24185	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
CMS1_k127_2169565_5	1354722.JQLS01000008_gene1346	1.638e-38	149.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,46NM0@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3264 Small-conductance mechanosensitive channel	kefA	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	DUF3772,MS_channel
CMS1_k127_2169565_2	1288298.rosmuc_03717	3.73e-215	670.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,46PFS@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0031 Cysteine synthase	cysB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2169565_4	314264.ROS217_19697	6.975e-151	489.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,2TTKQ@28211|Alphaproteobacteria,46PUU@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	trgB	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	GGACT,NUDIX
CMS1_k127_2169565_1	1123237.Salmuc_03567	1.646e-219	686.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	cfa	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_2169565_0	314264.ROS217_19682	2.921e-256	796.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,46P7J@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the DNA photolyase family	phrB	GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS1_k127_2169565_3	391613.RTM1035_07829	9.015e-197	616.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,46NAX@74030|Roseovarius	28211|Alphaproteobacteria	E	Aminotransferase, class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_2188947_1	314264.ROS217_08990	5.687e-141	451.0	COG3591@1|root,COG3591@2|Bacteria,1MXUN@1224|Proteobacteria,2TT3R@28211|Alphaproteobacteria,46P92@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the peptidase S1B family	blaSE	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
CMS1_k127_2188947_2	391613.RTM1035_19916	2.695e-111	368.0	COG3591@1|root,COG3591@2|Bacteria,1MXUN@1224|Proteobacteria,2U5EK@28211|Alphaproteobacteria,46NH5@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the peptidase S1B family	-	-	-	ko:K04775	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin,Trypsin_2
CMS1_k127_2188947_4	1354722.JQLS01000008_gene3635	4.243e-81	274.0	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,46NWN@74030|Roseovarius	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	ibpA	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
CMS1_k127_2188947_0	391613.RTM1035_19926	2.103e-188	596.0	COG3126@1|root,COG3187@1|root,COG3650@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,COG3650@2|Bacteria,1MXIV@1224|Proteobacteria,2U2HT@28211|Alphaproteobacteria,46NR9@74030|Roseovarius	28211|Alphaproteobacteria	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	-	-	-	-	-	-	-	-	-	META,MliC,YscW
CMS1_k127_2188947_3	89187.ISM_10775	5.128e-95	312.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46QGK@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_2195151_1	1354722.JQLS01000008_gene2148	8.033e-201	630.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,46Q4I@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_2195151_3	1354722.JQLS01000008_gene590	5.434e-71	245.0	COG0494@1|root,COG0494@2|Bacteria,1MZ5D@1224|Proteobacteria,2UBX9@28211|Alphaproteobacteria,46R85@74030|Roseovarius	28211|Alphaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_2195151_4	351016.RAZWK3B_07939	4.117e-58	205.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,2P394@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_39715	-	-	-	-	-	-	-	-	-	-	-	DUF1178
CMS1_k127_2195151_2	1354722.JQLS01000008_gene588	2.649e-99	327.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2TUR9@28211|Alphaproteobacteria,46PJR@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	csgA	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2195151_0	1354722.JQLS01000008_gene587	9.038e-233	725.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,46P0H@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_2197646_0	314264.ROS217_10202	0.0	1050.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TRBN@28211|Alphaproteobacteria,46QJG@74030|Roseovarius	28211|Alphaproteobacteria	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_2197646_1	1288298.rosmuc_00114	2.876e-192	604.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,46PX4@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
CMS1_k127_2197646_2	314264.ROS217_10192	6.243e-141	447.0	COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,46PWP@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N_3
CMS1_k127_2197646_3	1288298.rosmuc_00112	6.46e-95	313.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,46Q18@74030|Roseovarius	28211|Alphaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS1_k127_2207028_8	1402135.SUH3_14685	2.477e-11	70.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TUEF@28211|Alphaproteobacteria,3ZX20@60136|Sulfitobacter	28211|Alphaproteobacteria	EH	Sulfopyruvate decarboxylase subunit beta	MA20_15005	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_2207028_4	391593.RCCS2_12614	2.244e-102	334.0	COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria,2TT20@28211|Alphaproteobacteria,2P1RD@2433|Roseobacter	28211|Alphaproteobacteria	C	Sulfopyruvate decarboxylase subunit alpha	MA20_15000	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
CMS1_k127_2207028_7	391613.RTM1035_17042	8.632e-51	183.0	COG0589@1|root,COG0589@2|Bacteria,1RCP0@1224|Proteobacteria,2U6H4@28211|Alphaproteobacteria,46QSN@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_2207028_2	314264.ROS217_11231	7.032e-181	571.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,2TU6B@28211|Alphaproteobacteria,46QBW@74030|Roseovarius	28211|Alphaproteobacteria	E	and related Zn-dependent dehydrogenases	yjjN	GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034193,GO:0034195,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.14,1.1.1.380	ko:K00008,ko:K08322	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896,R10848	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2207028_3	351016.RAZWK3B_00820	6.294e-119	386.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TTVF@28211|Alphaproteobacteria,2P2MC@2433|Roseobacter	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	gno	-	1.1.1.127,1.1.1.69	ko:K00046,ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_2207028_0	1288298.rosmuc_00842	2.096e-258	799.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TS04@28211|Alphaproteobacteria,46PYI@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD_3	-	1.1.1.308	ko:K15509	-	-	-	-	ko00000,ko01000	-	-	-	Histidinol_dh
CMS1_k127_2207028_1	246200.SPO0593	2.17e-250	776.0	COG1593@1|root,COG1593@2|Bacteria,1MUHY@1224|Proteobacteria,2TS43@28211|Alphaproteobacteria,4NB33@97050|Ruegeria	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_2207028_5	246200.SPO0592	4.156e-85	286.0	COG3090@1|root,COG3090@2|Bacteria,1RBHY@1224|Proteobacteria,2U681@28211|Alphaproteobacteria,4NB8Z@97050|Ruegeria	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_2207028_6	744979.R2A130_1999	1.987e-70	238.0	COG1638@1|root,COG1638@2|Bacteria,1PFSU@1224|Proteobacteria,2TVA1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Trap dicarboxylate transporter, dctp subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_2220983_0	1121479.AUBS01000007_gene2302	6.78e-287	883.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS1_k127_2220983_5	1288298.rosmuc_01940	5.742e-62	214.0	2AQJG@1|root,31FS9@2|Bacteria,1RHQH@1224|Proteobacteria,2U9NC@28211|Alphaproteobacteria,46QV5@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2220983_7	391613.RTM1035_13593	1.799e-44	164.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,46R0V@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1393 Arsenate reductase and related proteins, glutaredoxin family	MA20_27840	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS1_k127_2220983_8	89187.ISM_13955	6.494e-35	134.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,46R5K@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1278 Cold shock proteins	cspA4	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_2220983_2	314264.ROS217_18497	3.518e-183	583.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,46PEX@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
CMS1_k127_2220983_3	314264.ROS217_18487	3.653e-111	366.0	COG2304@1|root,COG2304@2|Bacteria,1PH4N@1224|Proteobacteria,2U5G2@28211|Alphaproteobacteria,46PKJ@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1194
CMS1_k127_2220983_4	314264.ROS217_18482	3.197e-92	304.0	COG1846@1|root,COG1846@2|Bacteria,1RA1V@1224|Proteobacteria,2U5W6@28211|Alphaproteobacteria,46QGF@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, MarR family	mucS	-	-	-	-	-	-	-	-	-	-	-	HTH_27
CMS1_k127_2220983_9	1123237.Salmuc_05594	1.647e-26	112.0	COG2938@1|root,COG2938@2|Bacteria,1N6SJ@1224|Proteobacteria,2UFF5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
CMS1_k127_2220983_6	314264.ROS217_18472	8.575e-61	218.0	COG1813@1|root,COG1813@2|Bacteria,1N8B7@1224|Proteobacteria,2TXGH@28211|Alphaproteobacteria,46QTQ@74030|Roseovarius	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
CMS1_k127_2220983_1	314264.ROS217_18467	1.315e-224	698.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,46NX0@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2222545_0	1265490.JHVY01000021_gene3695	4.227e-44	169.0	COG5285@1|root,COG5285@2|Bacteria,1RM57@1224|Proteobacteria	1224|Proteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_2267599_0	351016.RAZWK3B_06242	0.0	2001.0	COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria,2P1E5@2433|Roseobacter	28211|Alphaproteobacteria	H	COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
CMS1_k127_2267599_8	314264.ROS217_08024	2.221e-10	66.0	2EGPV@1|root,2ZZD4@2|Bacteria,1Q5HS@1224|Proteobacteria,2VBVQ@28211|Alphaproteobacteria,46R9E@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2267599_5	314264.ROS217_08019	1.325e-69	238.0	COG0454@1|root,COG0456@2|Bacteria,1RHB3@1224|Proteobacteria,2UDFB@28211|Alphaproteobacteria,46QSX@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ysnE	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS1_k127_2267599_2	391613.RTM1035_17347	1.814e-196	616.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TQWN@28211|Alphaproteobacteria,46P0A@74030|Roseovarius	28211|Alphaproteobacteria	S	GTPases (G3E family)	cobW	-	-	ko:K02234	-	-	-	-	ko00000,ko00001	-	-	-	CobW_C,cobW
CMS1_k127_2267599_6	1288298.rosmuc_00908	5.967e-55	194.0	COG5469@1|root,COG5469@2|Bacteria,1N7Q2@1224|Proteobacteria,2UG4K@28211|Alphaproteobacteria,46QXH@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1636)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1636
CMS1_k127_2267599_4	391613.RTM1035_17337	1.074e-69	240.0	2BVTZ@1|root,32U84@2|Bacteria,1RIIV@1224|Proteobacteria,2UAZD@28211|Alphaproteobacteria,46NW0@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2267599_3	391613.RTM1035_17332	2.121e-114	371.0	COG5446@1|root,COG5446@2|Bacteria,1RBWQ@1224|Proteobacteria,2U9NN@28211|Alphaproteobacteria,46QEQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Probable cobalt transporter subunit (CbtA)	cbtA	-	-	-	-	-	-	-	-	-	-	-	CbtA
CMS1_k127_2267599_7	1288298.rosmuc_00905	8.838e-24	103.0	2EKSU@1|root,33EGJ@2|Bacteria,1NGQH@1224|Proteobacteria,2UJHI@28211|Alphaproteobacteria,46RAM@74030|Roseovarius	28211|Alphaproteobacteria	S	Probable cobalt transporter subunit (CbtB)	cbtB	-	-	-	-	-	-	-	-	-	-	-	CbtB
CMS1_k127_2267599_1	1354722.JQLS01000008_gene3321	0.0	1833.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,46PKV@74030|Roseovarius	28211|Alphaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
CMS1_k127_2276676_1	391624.OIHEL45_17891	2.416e-80	276.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,2TTSE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	copB	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_2276676_0	391626.OAN307_c42300	1.947e-99	326.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,2TQRB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Selenium-binding protein	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
CMS1_k127_2311370_0	391613.RTM1035_07213	1.221e-203	637.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,46NST@74030|Roseovarius	28211|Alphaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS1_k127_2311370_3	439496.RBY4I_3230	2.599e-71	248.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
CMS1_k127_2311370_2	1089551.KE386572_gene2233	8.081e-84	286.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,4BSGF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_2311370_1	314264.ROS217_18522	5.176e-147	468.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2TQN2@28211|Alphaproteobacteria,46PG7@74030|Roseovarius	28211|Alphaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS1_k127_2314633_2	1469613.JT55_00100	1.091e-63	222.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,3FCV4@34008|Rhodovulum	28211|Alphaproteobacteria	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_2314633_0	314264.ROS217_08830	1.394e-145	465.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,46Q99@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0560 Phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
CMS1_k127_2314633_1	89187.ISM_10606	1.428e-73	250.0	COG0054@1|root,COG0054@2|Bacteria,1RHCZ@1224|Proteobacteria,2U5EC@28211|Alphaproteobacteria,46RUI@74030|Roseovarius	28211|Alphaproteobacteria	H	6,7-dimethyl-8-ribityllumazine synthase	ribH2	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS1_k127_231502_0	999550.KI421507_gene1120	0.0	1050.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2TTA4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS1_k127_231502_1	1288298.rosmuc_02625	2.639e-44	162.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,2UC3P@28211|Alphaproteobacteria,46R4S@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
CMS1_k127_231502_2	1354722.JQLS01000008_gene2055	3.556e-28	114.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,46P5G@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_233192_1	1288298.rosmuc_03738	3.639e-65	225.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,46PXA@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	cysA	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_233192_0	1354722.JQLS01000008_gene2442	9.554e-280	862.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,46QCE@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	fadD3	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS1_k127_2337019_2	314264.ROS217_14146	5.193e-123	399.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,46NZE@74030|Roseovarius	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS1_k127_2337019_0	351016.RAZWK3B_10271	2.371e-200	629.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,2P2K3@2433|Roseobacter	28211|Alphaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2337019_1	1288298.rosmuc_01869	1.981e-176	556.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,46NCA@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0287 Prephenate dehydrogenase	tyrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_2337019_3	314264.ROS217_14131	4.219e-32	127.0	COG3921@1|root,COG3921@2|Bacteria,1PZMM@1224|Proteobacteria,2TR6H@28211|Alphaproteobacteria,46Q86@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
CMS1_k127_2354645_2	314264.ROS217_12016	4.32e-137	438.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,46PTF@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_2354645_8	1288298.rosmuc_00727	1.785e-43	160.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2U70U@28211|Alphaproteobacteria,46R21@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS1_k127_2354645_3	89187.ISM_12450	7.321e-135	436.0	COG0697@1|root,COG0697@2|Bacteria,1NDKG@1224|Proteobacteria,2U0DF@28211|Alphaproteobacteria,46NTZ@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
CMS1_k127_2354645_0	1288298.rosmuc_00726	9.499e-275	847.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2TR3D@28211|Alphaproteobacteria,46NUB@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1760 L-serine deaminase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CMS1_k127_2354645_5	1354722.JQLS01000008_gene131	7.849e-85	293.0	COG0625@1|root,COG0625@2|Bacteria,1R5G8@1224|Proteobacteria,2TVIS@28211|Alphaproteobacteria,46PCP@74030|Roseovarius	28211|Alphaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799,ko:K11208	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N,GST_N_3
CMS1_k127_2354645_7	351016.RAZWK3B_04345	6.681e-55	196.0	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,2UC11@28211|Alphaproteobacteria,2P3BE@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_03865	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
CMS1_k127_2354645_4	1288298.rosmuc_00723	6.732e-129	415.0	COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,2TVK6@28211|Alphaproteobacteria,46NT5@74030|Roseovarius	28211|Alphaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS1_k127_2354645_1	1288298.rosmuc_00722	1.154e-268	831.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,46Q7Y@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS1_k127_2354645_10	314264.ROS217_12051	3.269e-29	117.0	2E7FV@1|root,331YQ@2|Bacteria,1N8H6@1224|Proteobacteria,2UFPP@28211|Alphaproteobacteria,46R5G@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2354645_9	391593.RCCS2_07274	1.451e-33	129.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,2P3Q9@2433|Roseobacter	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS1_k127_2354645_6	292414.TM1040_2513	1.062e-65	225.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,4NCAS@97050|Ruegeria	28211|Alphaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS1_k127_2363453_0	1354722.JQLS01000008_gene2052	2.81e-321	990.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2TRZC@28211|Alphaproteobacteria,46NNU@74030|Roseovarius	28211|Alphaproteobacteria	T	containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS1_k127_2363453_2	391613.RTM1035_15562	1.269e-67	233.0	2BTTS@1|root,32P1D@2|Bacteria,1RIF8@1224|Proteobacteria,2U9KR@28211|Alphaproteobacteria,46QBQ@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2363453_3	391613.RTM1035_15557	2.368e-62	216.0	COG0745@1|root,COG0745@2|Bacteria,1MYGY@1224|Proteobacteria,2U9GF@28211|Alphaproteobacteria,46QVT@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_2363453_1	1354722.JQLS01000008_gene2049	6.627e-169	535.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2TSZS@28211|Alphaproteobacteria,46P3H@74030|Roseovarius	28211|Alphaproteobacteria	LT	EXOIII	polC	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T,VRR_NUC
CMS1_k127_2366689_1	1354722.JQLS01000008_gene637	3.36e-52	188.0	COG2197@1|root,COG2197@2|Bacteria,1RAAY@1224|Proteobacteria,2U69Z@28211|Alphaproteobacteria,46PR9@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS,PAS_3,PAS_9
CMS1_k127_2366689_0	1354722.JQLS01000008_gene638	1.534e-207	655.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,46NP6@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2376399_0	1354722.JQLS01000008_gene1061	9.817e-215	670.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria,46NUW@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2376399_1	388739.RSK20926_03664	7.959e-44	162.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TSCF@28211|Alphaproteobacteria,2P1IC@2433|Roseobacter	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2383507_2	1288298.rosmuc_03434	7.376e-62	214.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,46QAK@74030|Roseovarius	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2383507_3	1354722.JQLS01000008_gene1057	1.186e-51	186.0	2E4H4@1|root,32ZC8@2|Bacteria,1N7UT@1224|Proteobacteria,2UHEH@28211|Alphaproteobacteria,46QX1@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2383507_1	351016.RAZWK3B_17403	2.505e-171	542.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2P0Z6@2433|Roseobacter	28211|Alphaproteobacteria	C	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	MA20_25935	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_2383507_0	1354722.JQLS01000008_gene1055	2.22e-193	608.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,46P7X@74030|Roseovarius	28211|Alphaproteobacteria	S	related to penicillin acylase	quiP	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_2395834_2	1288298.rosmuc_03752	1.426e-161	511.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,46QEV@74030|Roseovarius	28211|Alphaproteobacteria	M	shape-determining protein	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_2395834_4	391613.RTM1035_15032	3.8e-64	225.0	2C7S8@1|root,32RJQ@2|Bacteria,1N2C7@1224|Proteobacteria,2UBZK@28211|Alphaproteobacteria,46PZ4@74030|Roseovarius	28211|Alphaproteobacteria	-	-	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	-
CMS1_k127_2395834_0	1354722.JQLS01000008_gene2454	0.0	1117.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,46PMT@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0768 Cell division protein FtsI penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_2395834_1	391613.RTM1035_15042	4.339e-217	680.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2TSM0@28211|Alphaproteobacteria,46NS9@74030|Roseovarius	28211|Alphaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS1_k127_2395834_3	1288298.rosmuc_03756	8.098e-156	496.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2TSUU@28211|Alphaproteobacteria,46PY0@74030|Roseovarius	28211|Alphaproteobacteria	EH	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
CMS1_k127_2395834_5	1354722.JQLS01000008_gene2457	2.795e-21	94.0	2C5G4@1|root,2Z7MU@2|Bacteria,1N9VI@1224|Proteobacteria,2TTAT@28211|Alphaproteobacteria,46PD0@74030|Roseovarius	28211|Alphaproteobacteria	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
CMS1_k127_2397708_2	1461693.ATO10_13044	2.591e-74	250.0	COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,2TTKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide	amiF	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_2397708_1	1547437.LL06_20385	1.93e-130	417.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,2TSQZ@28211|Alphaproteobacteria,43N27@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_2397708_0	1469613.JT55_13320	1.234e-207	657.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2UPJ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
CMS1_k127_2397708_3	1469613.JT55_13315	2.621e-19	89.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,2TUVZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2	MA20_17545	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_2401940_1	1354722.JQLS01000008_gene2548	7.062e-139	446.0	COG3284@1|root,COG3284@2|Bacteria,1MVRZ@1224|Proteobacteria,2TSRW@28211|Alphaproteobacteria,46QBX@74030|Roseovarius	28211|Alphaproteobacteria	KQ	COG3284 Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8
CMS1_k127_2401940_5	1080067.BAZH01000035_gene2174	6.437e-06	49.0	28VP7@1|root,2ZHR6@2|Bacteria,1P8M3@1224|Proteobacteria,1SVC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2401940_2	1123360.thalar_02792	1.092e-102	337.0	COG2995@1|root,COG2995@2|Bacteria,1RAQ9@1224|Proteobacteria,2U6A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
CMS1_k127_2401940_3	83219.PM02_06665	1.259e-83	287.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2TT3D@28211|Alphaproteobacteria,3ZWM1@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
CMS1_k127_2401940_0	1123360.thalar_02794	2.594e-315	978.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,2TSTX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Paraquat-inducible protein B	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
CMS1_k127_2401940_4	1123360.thalar_02795	1.525e-44	165.0	COG3009@1|root,COG3009@2|Bacteria,1RH03@1224|Proteobacteria,2U9EI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
CMS1_k127_2407913_0	1354722.JQLS01000008_gene1996	7.194e-117	383.0	COG2861@1|root,COG2861@2|Bacteria,1RBJ3@1224|Proteobacteria,2TSWM@28211|Alphaproteobacteria,46QCY@74030|Roseovarius	28211|Alphaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_2
CMS1_k127_2407913_1	1354722.JQLS01000008_gene1994	7.644e-100	327.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2U5H3@28211|Alphaproteobacteria,46PJQ@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS1_k127_2407913_3	1288298.rosmuc_01132	4.076e-90	302.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VFYC@28211|Alphaproteobacteria,46QIG@74030|Roseovarius	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_2407913_2	1354722.JQLS01000008_gene1992	1.901e-94	310.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,46NP9@74030|Roseovarius	28211|Alphaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_2421585_0	314264.ROS217_21337	3.776e-261	808.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSK4@28211|Alphaproteobacteria,46PEB@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	MA20_26350	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_2421585_1	1288298.rosmuc_01305	7.509e-65	224.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2U08T@28211|Alphaproteobacteria,46PHT@74030|Roseovarius	28211|Alphaproteobacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291,ko:K18163	ko00906,ko01062,ko01100,ko01110,ko04714,map00906,map01062,map01100,map01110,map04714	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	SQS_PSY
CMS1_k127_2426664_1	1288298.rosmuc_02258	8.097e-26	106.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,46NDZ@74030|Roseovarius	28211|Alphaproteobacteria	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_2426664_0	1354722.JQLS01000008_gene2559	2.082e-176	557.0	COG1530@1|root,COG1530@2|Bacteria,1MWBR@1224|Proteobacteria,2TU44@28211|Alphaproteobacteria,46PYZ@74030|Roseovarius	28211|Alphaproteobacteria	J	COG1530 Ribonucleases G and E	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
CMS1_k127_2426664_2	314264.ROS217_06314	1.656e-25	109.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VAYQ@28211|Alphaproteobacteria,46RBA@74030|Roseovarius	28211|Alphaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	-	-	-	-	-	-	-	-	-	YacG
CMS1_k127_2426664_3	375451.RD1_1845	3.577e-10	60.0	COG1961@1|root,COG1961@2|Bacteria,1PF4F@1224|Proteobacteria,2V7FP@28211|Alphaproteobacteria,2P3YH@2433|Roseobacter	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2430920_5	1354722.JQLS01000008_gene1804	9.308e-11	61.0	COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,2U1B5@28211|Alphaproteobacteria,46NPM@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_2430920_3	1354722.JQLS01000008_gene1803	8.397e-57	199.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2U95K@28211|Alphaproteobacteria,46R0M@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	MA20_41450	-	-	-	-	-	-	-	-	-	-	-	DUF498
CMS1_k127_2430920_2	1354722.JQLS01000008_gene1802	2.844e-96	319.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,46PZ5@74030|Roseovarius	28211|Alphaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CMS1_k127_2430920_1	391613.RTM1035_11610	2.917e-115	374.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2TUSG@28211|Alphaproteobacteria,46NKG@74030|Roseovarius	28211|Alphaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CMS1_k127_2430920_0	314264.ROS217_21787	8.403e-150	475.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,46NN2@74030|Roseovarius	28211|Alphaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS1_k127_2430920_4	314264.ROS217_21782	8.044e-16	78.0	COG3114@1|root,COG3114@2|Bacteria,1NGTN@1224|Proteobacteria,2UJD6@28211|Alphaproteobacteria,46R96@74030|Roseovarius	28211|Alphaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
CMS1_k127_2430920_6	1354722.JQLS01000008_gene1798	4.663e-07	51.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,46NGH@74030|Roseovarius	28211|Alphaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	ccmG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_2449499_0	1342301.JASD01000008_gene468	2.519e-115	371.0	COG5276@1|root,COG5276@2|Bacteria,1QWJ6@1224|Proteobacteria,2TWYY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	-	-	-	-	-	-	-	-	-	SBP56
CMS1_k127_2449499_1	391626.OAN307_c42310	1.741e-104	342.0	2AI77@1|root,318MJ@2|Bacteria,1MXJB@1224|Proteobacteria,2TW9U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2449499_2	1288298.rosmuc_00979	1.71e-72	246.0	COG3193@1|root,COG3193@2|Bacteria,1RB2H@1224|Proteobacteria,2U7XA@28211|Alphaproteobacteria,46QQE@74030|Roseovarius	28211|Alphaproteobacteria	S	protein, possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
CMS1_k127_2449499_3	351016.RAZWK3B_19291	2.693e-54	191.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria,2P28P@2433|Roseobacter	28211|Alphaproteobacteria	H	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
CMS1_k127_2451364_0	1122180.Lokhon_02297	3.457e-140	447.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2P8AR@245186|Loktanella	28211|Alphaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_2451364_1	391613.RTM1035_16287	8.835e-33	133.0	2EMKN@1|root,3339E@2|Bacteria,1N9SW@1224|Proteobacteria,2UF94@28211|Alphaproteobacteria,46R30@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2451364_2	314264.ROS217_06905	2.21e-31	129.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,46Q75@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	3.1.2.30,4.1.3.34	ko:K01644,ko:K14451	ko00630,ko01120,ko01200,ko02020,map00630,map01120,map01200,map02020	M00373	R00362,R10612	RC00004,RC00014,RC00067,RC01118	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_2454693_0	1354722.JQLS01000008_gene2391	1.662e-213	664.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,46NNN@74030|Roseovarius	28211|Alphaproteobacteria	U	Type II IV secretion system protein, TadA subfamily	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS1_k127_2454693_1	1354722.JQLS01000008_gene2392	9.464e-175	551.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria,46PNH@74030|Roseovarius	28211|Alphaproteobacteria	U	COG4965 Flp pilus assembly protein TadB	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_2454693_2	1354722.JQLS01000008_gene2393	3.068e-163	519.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria,46P4U@74030|Roseovarius	28211|Alphaproteobacteria	NU	Type II IV secretion system protein, TadC subfamily	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_2454693_3	391613.RTM1035_14547	1.877e-53	191.0	COG0457@1|root,COG0457@2|Bacteria,1RFAH@1224|Proteobacteria,2U7KD@28211|Alphaproteobacteria,46QTV@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_16,TPR_2,TPR_8
CMS1_k127_245641_1	1288298.rosmuc_03399	2.14e-147	472.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TU2S@28211|Alphaproteobacteria,46NQZ@74030|Roseovarius	28211|Alphaproteobacteria	G	COG3588 Fructose-1,6-bisphosphate aldolase	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
CMS1_k127_245641_0	1354722.JQLS01000008_gene1029	2.873e-228	710.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,46PJF@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS1_k127_245641_2	89187.ISM_04655	4.275e-25	108.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria,46QF6@74030|Roseovarius	28211|Alphaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03768,ko:K09565	ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Pro_isomerase
CMS1_k127_246147_0	1354722.JQLS01000008_gene3164	0.0	1338.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,46NNV@74030|Roseovarius	28211|Alphaproteobacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
CMS1_k127_246147_3	985054.JQEZ01000004_gene750	1.826e-91	306.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,4NA1N@97050|Ruegeria	28211|Alphaproteobacteria	M	Nucleotidyl transferase	MA20_24100	-	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
CMS1_k127_246147_1	391613.RTM1035_17417	4.775e-148	475.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,46P0I@74030|Roseovarius	28211|Alphaproteobacteria	S	related to Ser Thr protein kinases	MA20_24090	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,TsaE
CMS1_k127_246147_4	314264.ROS217_10627	4.211e-64	222.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2UBQ9@28211|Alphaproteobacteria,46QQM@74030|Roseovarius	28211|Alphaproteobacteria	S	ATPase or kinase	-	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
CMS1_k127_246147_2	1354722.JQLS01000008_gene3160	5.091e-115	376.0	COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria,46Q11@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2202 FOG PAS PAC domain	divL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,PAS_8
CMS1_k127_2462754_0	314264.ROS217_14276	0.0	1461.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,46NEK@74030|Roseovarius	28211|Alphaproteobacteria	O	ATP-dependent Clp protease ATP-binding subunit ClpA	clpA	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_2462754_3	1288298.rosmuc_01899	1.186e-124	404.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,46QDJ@74030|Roseovarius	28211|Alphaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CMS1_k127_2462754_2	391613.RTM1035_13798	1.273e-152	483.0	COG2227@1|root,COG2227@2|Bacteria,1QV6Z@1224|Proteobacteria,2TWBU@28211|Alphaproteobacteria,46PNV@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2462754_5	314264.ROS217_14311	8.604e-95	313.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,46Q46@74030|Roseovarius	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS1_k127_2462754_1	1288298.rosmuc_01906	2.216e-316	970.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,46NXE@74030|Roseovarius	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS1_k127_2462754_4	314264.ROS217_14321	5.552e-103	338.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,46NM2@74030|Roseovarius	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS1_k127_2465093_7	439496.RBY4I_3266	1.357e-33	130.0	COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UF49@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	disulfide bond formation protein DsbB	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
CMS1_k127_2465093_6	351016.RAZWK3B_17103	2.596e-68	237.0	COG1522@1|root,COG1522@2|Bacteria,1MZ9D@1224|Proteobacteria,2U7BV@28211|Alphaproteobacteria,2P37F@2433|Roseobacter	28211|Alphaproteobacteria	K	Transcriptional Regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
CMS1_k127_2465093_1	391613.RTM1035_07408	5.127e-167	528.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TRTG@28211|Alphaproteobacteria,46P4C@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS1_k127_2465093_0	1288298.rosmuc_03584	5.932e-204	638.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSBQ@28211|Alphaproteobacteria,46PZG@74030|Roseovarius	28211|Alphaproteobacteria	E	ornithine cyclodeaminase, mu-crystallin homolog	arcB	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS1_k127_2465093_9	1342301.JASD01000008_gene3188	1.568e-14	80.0	2C5FY@1|root,33BY6@2|Bacteria,1NH37@1224|Proteobacteria,2UJVQ@28211|Alphaproteobacteria,3ZY7Q@60136|Sulfitobacter	28211|Alphaproteobacteria	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS1_k127_2465093_8	89187.ISM_14510	2.366e-28	124.0	COG1595@1|root,COG1595@2|Bacteria,1NBX6@1224|Proteobacteria,2UHF0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2465093_5	1354722.JQLS01000008_gene1692	2.968e-103	345.0	2EIWD@1|root,33CMP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2465093_2	1354722.JQLS01000008_gene1693	7.001e-138	443.0	COG1215@1|root,COG1215@2|Bacteria,1R304@1224|Proteobacteria,2TZV1@28211|Alphaproteobacteria,46RX1@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2465093_3	391613.RTM1035_03485	2.844e-134	437.0	COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,2TU1A@28211|Alphaproteobacteria,46NDP@74030|Roseovarius	28211|Alphaproteobacteria	M	Male sterility protein	-	-	1.1.1.410	ko:K22025	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
CMS1_k127_2465093_4	391613.RTM1035_03520	4.671e-109	357.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2TSVI@28211|Alphaproteobacteria,46PBQ@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the hyi family	-	-	5.3.1.35	ko:K22131	-	-	-	-	ko00000,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_2491566_2	1288298.rosmuc_02709	3.672e-113	370.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2TV0F@28211|Alphaproteobacteria,46RQI@74030|Roseovarius	28211|Alphaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	hbaR	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_2491566_4	391613.RTM1035_15997	2.381e-91	306.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,2U5AF@28211|Alphaproteobacteria,46QSQ@74030|Roseovarius	28211|Alphaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
CMS1_k127_2491566_5	1288298.rosmuc_02711	3.367e-29	119.0	29Q31@1|root,30B1N@2|Bacteria,1QTAR@1224|Proteobacteria,2V1VJ@28211|Alphaproteobacteria,46RYQ@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2491566_3	1288298.rosmuc_02712	1.169e-93	313.0	COG1845@1|root,COG1845@2|Bacteria,1RG3S@1224|Proteobacteria,2U15W@28211|Alphaproteobacteria,46RGX@74030|Roseovarius	28211|Alphaproteobacteria	C	Cytochrome c oxidase subunit III	norE	-	-	ko:K02164	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	COX3
CMS1_k127_2491566_0	1288298.rosmuc_02713	0.0	1047.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2TU4K@28211|Alphaproteobacteria,46NWM@74030|Roseovarius	28211|Alphaproteobacteria	P	COG4548 Nitric oxide reductase activation protein	norD	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
CMS1_k127_2491566_1	571166.KI421509_gene3327	4.773e-148	469.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TTQJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM ATPase associated with various cellular activities, AAA_5	norQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
CMS1_k127_2493988_1	648757.Rvan_3169	2.056e-79	272.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,2TVMP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	restriction endonuclease	mrr	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
CMS1_k127_2493988_0	1288298.rosmuc_02061	0.0	1216.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,46PMR@74030|Roseovarius	28211|Alphaproteobacteria	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_2493988_3	1354722.JQLS01000008_gene799	4.289e-27	111.0	2C7DQ@1|root,33I14@2|Bacteria,1NGNT@1224|Proteobacteria,2UJUT@28211|Alphaproteobacteria,46R9G@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2493988_2	439497.RR11_1211	4.898e-61	213.0	2AFS6@1|root,315U5@2|Bacteria,1RHM3@1224|Proteobacteria,2U9EY@28211|Alphaproteobacteria,4NC89@97050|Ruegeria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2495129_1	1354722.JQLS01000008_gene891	1.888e-102	337.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2U5CW@28211|Alphaproteobacteria,46Q8C@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
CMS1_k127_2495129_0	351016.RAZWK3B_16455	1.932e-320	983.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2P19Q@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_2514942_0	391613.RTM1035_10970	0.0	1390.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,46QH1@74030|Roseovarius	28211|Alphaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_2514942_2	391613.RTM1035_10980	3.903e-55	194.0	2A0NG@1|root,30NSR@2|Bacteria,1RKKU@1224|Proteobacteria,2UAQB@28211|Alphaproteobacteria,46QZB@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2514942_1	1354722.JQLS01000008_gene1018	8.708e-160	510.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2TRXH@28211|Alphaproteobacteria,46NFP@74030|Roseovarius	28211|Alphaproteobacteria	M	Polysaccharide biosynthesis/export protein	bexD	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_2514992_2	571166.KI421509_gene445	1.271e-44	165.0	COG2374@1|root,COG2374@2|Bacteria,1NTH6@1224|Proteobacteria,2TVN3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_2514992_0	644107.SL1157_0069	7.129e-93	310.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2TTX1@28211|Alphaproteobacteria,4NBWR@97050|Ruegeria	28211|Alphaproteobacteria	O	DnaJ molecular chaperone homology domain	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
CMS1_k127_2514992_1	1123501.KB902310_gene63	4.968e-48	176.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG1247 Sortase and related acyltransferases	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS1_k127_2518899_0	375451.RD1_3864	1.094e-169	539.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2P494@2433|Roseobacter	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
CMS1_k127_2518899_1	571166.KI421509_gene1264	2.655e-116	375.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2TSJT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
CMS1_k127_2527467_2	1354722.JQLS01000008_gene260	3.923e-69	237.0	COG3637@1|root,COG3637@2|Bacteria,1RBBG@1224|Proteobacteria,2U5ED@28211|Alphaproteobacteria,46RJF@74030|Roseovarius	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	lpxQ	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl
CMS1_k127_2527467_1	1288298.rosmuc_02289	4.585e-107	352.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria,46NFF@74030|Roseovarius	28211|Alphaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
CMS1_k127_2527467_0	1288298.rosmuc_02290	4.37e-294	902.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,46PC2@74030|Roseovarius	28211|Alphaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00410,ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
CMS1_k127_2527467_3	1354722.JQLS01000008_gene263	1.682e-61	214.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,46PBB@74030|Roseovarius	28211|Alphaproteobacteria	P	COG2857 Cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
CMS1_k127_2533050_0	391613.RTM1035_07378	2.055e-229	718.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,46PRT@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
CMS1_k127_2533050_2	1354722.JQLS01000008_gene1698	2.62e-181	572.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,46RNG@74030|Roseovarius	28211|Alphaproteobacteria	M	Hexapeptide repeat of succinyl-transferase	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS1_k127_2533050_3	501479.ACNW01000080_gene4577	4.001e-37	141.0	COG0236@1|root,COG0236@2|Bacteria,1MZVG@1224|Proteobacteria,2UC3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Acyl carrier protein	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS1_k127_2533050_1	1288298.rosmuc_03581	1.747e-198	621.0	COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2TRYK@28211|Alphaproteobacteria,46NYF@74030|Roseovarius	28211|Alphaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF1	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_253682_6	1429916.X566_23760	6.723e-30	125.0	COG0438@1|root,COG0438@2|Bacteria,1PJ7G@1224|Proteobacteria,2U2TC@28211|Alphaproteobacteria,3JVKZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_253682_4	1417296.U879_17200	4.253e-62	221.0	COG1086@1|root,COG1086@2|Bacteria,1N0T2@1224|Proteobacteria,2UIA1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS1_k127_253682_5	391626.OAN307_c36180	1.476e-43	168.0	COG0457@1|root,COG2518@1|root,COG0457@2|Bacteria,COG2518@2|Bacteria,1R9VH@1224|Proteobacteria,2U6AJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_253682_7	344747.PM8797T_12623	5.537e-10	70.0	COG0657@1|root,COG0657@2|Bacteria,2IXCK@203682|Planctomycetes	203682|Planctomycetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_253682_2	351016.RAZWK3B_00685	4.858e-86	292.0	2AJKK@1|root,30IGR@2|Bacteria,1RFE5@1224|Proteobacteria,2U784@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_253682_3	1288298.rosmuc_02176	5.626e-78	263.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,46QNF@74030|Roseovarius	28211|Alphaproteobacteria	M	Secreted and surface protein	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_253682_0	1354722.JQLS01000008_gene2820	7.476e-301	925.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria,46PYH@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_253682_1	1354722.JQLS01000001_gene4661	3.979e-170	537.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,46PQH@74030|Roseovarius	28211|Alphaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CMS1_k127_2545479_1	1121479.AUBS01000014_gene1165	1.114e-221	694.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS1_k127_2545479_0	571166.KI421509_gene1862	3.517e-243	756.0	COG2816@1|root,COG2816@2|Bacteria,1MV1F@1224|Proteobacteria,2TTRT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1180 Pyruvate-formate lyase-activating enzyme	MA20_26535	-	1.3.7.1	ko:K20449	ko00760,ko01120,map00760,map01120	-	R03164	RC02422	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_2556388_3	391613.RTM1035_16227	6.531e-24	100.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,46NA5@74030|Roseovarius	28211|Alphaproteobacteria	D	ATPase involved in cell division	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS1_k127_2556388_1	1288298.rosmuc_00677	1.134e-84	290.0	2AQPE@1|root,31FWZ@2|Bacteria,1RDS0@1224|Proteobacteria,2U708@28211|Alphaproteobacteria,46NJ0@74030|Roseovarius	28211|Alphaproteobacteria	S	MJ0042 family finger-like	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
CMS1_k127_2556388_0	1354722.JQLS01000008_gene3692	0.0	1307.0	COG0419@1|root,COG0419@2|Bacteria,1MWCT@1224|Proteobacteria,2TS61@28211|Alphaproteobacteria,46P0D@74030|Roseovarius	28211|Alphaproteobacteria	L	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
CMS1_k127_2556388_2	1288298.rosmuc_00322	3.427e-37	140.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,46QAV@74030|Roseovarius	28211|Alphaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_2569622_2	314264.ROS217_17562	1.333e-55	196.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,46Q7A@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2569622_1	391613.RTM1035_11160	1.304e-170	539.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,46QMJ@74030|Roseovarius	28211|Alphaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS1_k127_2569622_0	314264.ROS217_17552	9.514e-230	719.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,46NQT@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_2569622_3	391613.RTM1035_11170	1.439e-25	106.0	COG0582@1|root,COG0582@2|Bacteria,1Q7U3@1224|Proteobacteria,2VAXI@28211|Alphaproteobacteria,46RCC@74030|Roseovarius	28211|Alphaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_257627_2	314264.ROS217_17352	5.879e-259	806.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2TVYD@28211|Alphaproteobacteria,46NZ7@74030|Roseovarius	28211|Alphaproteobacteria	T	COG4564 Signal transduction histidine kinase	degS	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,sCache_2
CMS1_k127_257627_4	1288298.rosmuc_01188	2.733e-197	622.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TUH6@28211|Alphaproteobacteria,46P82@74030|Roseovarius	28211|Alphaproteobacteria	P	And related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_257627_3	1288298.rosmuc_01189	7.644e-226	701.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,46PXE@74030|Roseovarius	28211|Alphaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_257627_5	314264.ROS217_17367	2.367e-176	556.0	COG4665@1|root,COG4665@2|Bacteria,1MVFC@1224|Proteobacteria,2TTID@28211|Alphaproteobacteria,46P1Z@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_257627_0	391613.RTM1035_06913	0.0	1313.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,46PWS@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	dctM6	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_257627_1	391613.RTM1035_10650	0.0	1005.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,46PWT@74030|Roseovarius	28211|Alphaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CMS1_k127_257627_6	314264.ROS217_21667	1.121e-161	514.0	COG2931@1|root,COG2931@2|Bacteria,1MXD5@1224|Proteobacteria,2TS29@28211|Alphaproteobacteria,46PU8@74030|Roseovarius	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_257627_7	1354722.JQLS01000008_gene1146	1.157e-140	449.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,46NK0@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	MA20_19195	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_257627_8	1288298.rosmuc_01246	1.58e-71	243.0	COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria,2U17B@28211|Alphaproteobacteria,46Q8Z@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0591 Na proline symporter	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_257921_4	351016.RAZWK3B_20596	2.162e-61	219.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,2P32W@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0633 Ferredoxin	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS1_k127_257921_5	351016.RAZWK3B_20606	1.578e-59	211.0	COG3409@1|root,COG3409@2|Bacteria,1RIC1@1224|Proteobacteria,2UAB2@28211|Alphaproteobacteria,2P397@2433|Roseobacter	28211|Alphaproteobacteria	M	peptidoglycan-binding domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
CMS1_k127_257921_3	89187.ISM_07095	3.515e-161	515.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,46NN9@74030|Roseovarius	28211|Alphaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS1_k127_257921_6	1354722.JQLS01000008_gene724	4.493e-23	102.0	COG5457@1|root,COG5457@2|Bacteria,1QTKR@1224|Proteobacteria,2VB87@28211|Alphaproteobacteria,46R7G@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1127
CMS1_k127_257921_7	1288298.rosmuc_00997	2.524e-21	102.0	2ACRH@1|root,312C8@2|Bacteria,1PQIB@1224|Proteobacteria,2V2X9@28211|Alphaproteobacteria,46R7W@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_257921_0	314264.ROS217_06359	1.326e-280	865.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2TRKE@28211|Alphaproteobacteria,46PHN@74030|Roseovarius	28211|Alphaproteobacteria	K	Pfam:DUF955	pccR	-	-	ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_3,HTH_31,Peptidase_M78
CMS1_k127_257921_1	1354722.JQLS01000008_gene2565	5.461e-208	653.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2TV76@28211|Alphaproteobacteria,46PRZ@74030|Roseovarius	28211|Alphaproteobacteria	NU	Type II secretion system (T2SS), protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CMS1_k127_257921_2	1354722.JQLS01000008_gene2566	6.592e-193	604.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,46NZX@74030|Roseovarius	28211|Alphaproteobacteria	NU	Type II/IV secretion system protein	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS1_k127_2583489_1	391613.RTM1035_18050	8.493e-151	481.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,46NZ3@74030|Roseovarius	28211|Alphaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2583489_0	1288298.rosmuc_00116	3.254e-226	704.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQYP@28211|Alphaproteobacteria,46N9E@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_259347_2	314264.ROS217_10687	8.33e-134	429.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria,46QG9@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_259347_6	1288298.rosmuc_00937	9.59e-69	240.0	COG3439@1|root,COG3439@2|Bacteria,1RIVW@1224|Proteobacteria,2U9R5@28211|Alphaproteobacteria,46QR9@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_259347_1	1354722.JQLS01000008_gene3147	7.638e-226	703.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,46NVF@74030|Roseovarius	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_259347_0	1354722.JQLS01000008_gene3146	4.896e-287	890.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSZ8@28211|Alphaproteobacteria,46P3S@74030|Roseovarius	28211|Alphaproteobacteria	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	alsS	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_259347_3	1354722.JQLS01000008_gene3144	5.188e-119	385.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,46NPA@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0349 Ribonuclease D	rnd1	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
CMS1_k127_259347_4	1288298.rosmuc_00003	1.41e-85	287.0	COG5375@1|root,COG5375@2|Bacteria,1RJ23@1224|Proteobacteria,2UAJS@28211|Alphaproteobacteria,46P0F@74030|Roseovarius	28211|Alphaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
CMS1_k127_259347_5	1354722.JQLS01000008_gene3142	2.338e-73	250.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2UAPK@28211|Alphaproteobacteria,46QPK@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
CMS1_k127_259347_7	1354722.JQLS01000008_gene3141	1.297e-28	117.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,46PR5@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1137 ABC-type (unclassified) transport system, ATPase component	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2609974_0	1354722.JQLS01000008_gene3522	8.467e-149	473.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2TTZY@28211|Alphaproteobacteria,46P5X@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1305 Transglutaminase-like enzymes	MA20_32430	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
CMS1_k127_2609974_3	1288298.rosmuc_00201	9.455e-133	426.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2U09K@28211|Alphaproteobacteria,46Q40@74030|Roseovarius	28211|Alphaproteobacteria	O	Proteasome-type protease	MA20_32445	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
CMS1_k127_2609974_7	1342299.Z947_1201	4.194e-90	308.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,2U5BH@28211|Alphaproteobacteria,3ZVAA@60136|Sulfitobacter	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	bioM	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
CMS1_k127_2609974_12	349102.Rsph17025_2319	6.685e-39	152.0	COG0619@1|root,COG0619@2|Bacteria,1RCBK@1224|Proteobacteria,2U70F@28211|Alphaproteobacteria,1FC1T@1060|Rhodobacter	28211|Alphaproteobacteria	P	Cobalt transport protein	bioN	-	-	ko:K16783	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25.1	-	-	CbiQ
CMS1_k127_2609974_11	391616.OA238_c42740	1.202e-81	275.0	COG1268@1|root,COG1268@2|Bacteria,1RD2B@1224|Proteobacteria,2U6U5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	BioY protein	bioY	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
CMS1_k127_2609974_10	1402135.SUH3_16225	9.539e-82	278.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Nitroreductase	pnbA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_2609974_4	83219.PM02_03305	1.76e-125	414.0	COG0183@1|root,COG0183@2|Bacteria,1R3S3@1224|Proteobacteria,2U0ZS@28211|Alphaproteobacteria,3ZW6M@60136|Sulfitobacter	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2609974_9	1402135.SUH3_16235	8.566e-89	306.0	COG0318@1|root,COG0318@2|Bacteria,1PBIG@1224|Proteobacteria,2TTHX@28211|Alphaproteobacteria,3ZWS1@60136|Sulfitobacter	28211|Alphaproteobacteria	IQ	AMP-binding enzyme	yhfT	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2609974_13	644076.SCH4B_1669	8.779e-34	131.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria,4NBAZ@97050|Ruegeria	28211|Alphaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
CMS1_k127_2609974_16	314260.PB2503_06197	5.398e-09	60.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
CMS1_k127_2609974_1	1337093.MBE-LCI_3241	2.212e-146	467.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2TS7I@28211|Alphaproteobacteria,2P80J@245186|Loktanella	28211|Alphaproteobacteria	K	containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K21826	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
CMS1_k127_2609974_15	1366046.HIMB11_02425	1.109e-17	86.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	DUF4433,MR_MLE_C,MR_MLE_N
CMS1_k127_2609974_14	211114.JOEF01000023_gene5794	4.341e-32	137.0	COG0010@1|root,COG0010@2|Bacteria,2HG7A@201174|Actinobacteria,4EC0H@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
CMS1_k127_2609974_5	34007.IT40_24395	8.586e-120	394.0	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,2U2W2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS1_k127_2609974_8	314265.R2601_01693	4.17e-89	296.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,2U71S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	isochorismatase, hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_2609974_2	314265.R2601_01698	1.499e-142	457.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2U1C5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
CMS1_k127_2609974_6	1123360.thalar_01115	8.604e-107	353.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	integral membrane protein	MA20_41380	-	-	-	-	-	-	-	-	-	-	-	DUF2189
CMS1_k127_2611526_0	331869.BAL199_29770	0.0	1004.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,4BPFU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_2611526_1	1088721.NSU_0963	1.862e-69	237.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,2K0I9@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS1_k127_2611706_2	1354722.JQLS01000008_gene3238	8.914e-135	433.0	COG1682@1|root,COG1682@2|Bacteria,1MWQZ@1224|Proteobacteria,2TUEJ@28211|Alphaproteobacteria,46PQU@74030|Roseovarius	28211|Alphaproteobacteria	GM	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
CMS1_k127_2611706_3	351016.RAZWK3B_03105	7.074e-99	328.0	COG3145@1|root,COG3145@2|Bacteria,1N5HB@1224|Proteobacteria,2U5C6@28211|Alphaproteobacteria,2P2V4@2433|Roseobacter	28211|Alphaproteobacteria	L	COG3145 Alkylated DNA repair protein	alkB	-	1.14.11.33	ko:K03919	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	2OG-FeII_Oxy_2
CMS1_k127_2611706_0	351016.RAZWK3B_03100	0.0	1133.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2P158@2433|Roseobacter	28211|Alphaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_2611706_1	981384.AEYW01000022_gene3518	6.757e-157	498.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,4NBFT@97050|Ruegeria	28211|Alphaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_2617586_2	1342301.JASD01000008_gene600	3.338e-43	158.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,3ZX56@60136|Sulfitobacter	28211|Alphaproteobacteria	H	Molybdopterin-guanine dinucleotide biosynthesis	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
CMS1_k127_2617586_0	314264.ROS217_22157	5.733e-100	329.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2TV2G@28211|Alphaproteobacteria,46P6A@74030|Roseovarius	28211|Alphaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_2617586_1	1354722.JQLS01000008_gene1941	2.721e-99	325.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VFYH@28211|Alphaproteobacteria,46PK3@74030|Roseovarius	28211|Alphaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS1_k127_2637161_4	1305735.JAFT01000005_gene2953	6.377e-93	311.0	COG4912@1|root,COG4912@2|Bacteria,1NKDG@1224|Proteobacteria,2TU19@28211|Alphaproteobacteria,2PDSJ@252301|Oceanicola	28211|Alphaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS1_k127_2637161_0	1354722.JQLS01000008_gene1790	0.0	1017.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,46NRB@74030|Roseovarius	28211|Alphaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS1_k127_2637161_2	1354722.JQLS01000008_gene1789	2.725e-212	673.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,46PYV@74030|Roseovarius	28211|Alphaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
CMS1_k127_2637161_3	1354722.JQLS01000008_gene1788	4.483e-104	341.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,46Q8S@74030|Roseovarius	28211|Alphaproteobacteria	S	haloacid dehalogenase-like hydrolase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_2637161_1	1288298.rosmuc_03318	4.342e-222	693.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TQVS@28211|Alphaproteobacteria,46NC8@74030|Roseovarius	28211|Alphaproteobacteria	E	Apparently involved in regulation of cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_2637161_6	195105.CN97_16395	2.15e-15	83.0	COG5642@1|root,COG5642@2|Bacteria,1RJWF@1224|Proteobacteria,2UAN5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
CMS1_k127_2637161_5	1054213.HMPREF9946_03954	1.946e-53	192.0	COG5654@1|root,COG5654@2|Bacteria,1RG4T@1224|Proteobacteria,2U7W1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
CMS1_k127_2647890_0	314264.ROS217_17767	0.0	1208.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,46PQR@74030|Roseovarius	28211|Alphaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_2647890_3	1288298.rosmuc_03397	8.784e-75	254.0	298HD@1|root,2ZVNE@2|Bacteria,1RDBR@1224|Proteobacteria,2U79Z@28211|Alphaproteobacteria,46QP3@74030|Roseovarius	28211|Alphaproteobacteria	S	Component of SufBCD complex	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2647890_1	391613.RTM1035_10950	3.697e-196	615.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,46PZP@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS1_k127_2647890_2	1288298.rosmuc_03395	1.021e-100	331.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2U5K0@28211|Alphaproteobacteria,46Q00@74030|Roseovarius	28211|Alphaproteobacteria	S	Twin-arginine translocation pathway signal sequence domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
CMS1_k127_2647890_4	391613.RTM1035_10965	5.107e-53	187.0	COG5425@1|root,COG5425@2|Bacteria,1N08I@1224|Proteobacteria,2UBVR@28211|Alphaproteobacteria,46R26@74030|Roseovarius	28211|Alphaproteobacteria	E	Usg-like family	usg	-	-	-	-	-	-	-	-	-	-	-	Usg
CMS1_k127_2647890_5	1123247.AUIJ01000006_gene3272	2.29e-32	127.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_2684277_0	391613.RTM1035_11055	0.0	1249.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,46Q4Q@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the transketolase family	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_2684277_3	1288298.rosmuc_03376	3.684e-54	194.0	COG1196@1|root,COG1196@2|Bacteria,1N0KA@1224|Proteobacteria,2UCJ9@28211|Alphaproteobacteria,46QTG@74030|Roseovarius	28211|Alphaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2684277_2	391613.RTM1035_11045	2.391e-64	222.0	COG3027@1|root,COG3027@2|Bacteria,1N8NY@1224|Proteobacteria,2UCRX@28211|Alphaproteobacteria,46QR4@74030|Roseovarius	28211|Alphaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	MA20_17980	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS1_k127_2684277_4	391613.RTM1035_11040	3.833e-51	185.0	COG4446@1|root,COG4446@2|Bacteria,1N8VI@1224|Proteobacteria,2UFQP@28211|Alphaproteobacteria,46QVI@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS1_k127_2684277_5	1123360.thalar_02029	4.483e-18	87.0	2E70E@1|root,331JA@2|Bacteria,1N876@1224|Proteobacteria,2UGK1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2684277_1	314264.ROS217_17677	2.383e-182	574.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,46QBZ@74030|Roseovarius	28211|Alphaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_2688817_2	1288298.rosmuc_01749	8.888e-29	116.0	COG3346@1|root,COG3346@2|Bacteria,1MWWG@1224|Proteobacteria,2U0N5@28211|Alphaproteobacteria,46NW8@74030|Roseovarius	28211|Alphaproteobacteria	S	SURF1 family	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
CMS1_k127_2688817_0	1354722.JQLS01000008_gene2373	2.821e-271	841.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria,46P1H@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0498 Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CMS1_k127_2688817_1	1288298.rosmuc_01751	1.089e-177	559.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,46NCC@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	mpp	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_268925_1	1288298.rosmuc_01613	3.124e-104	344.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2TS81@28211|Alphaproteobacteria,46PWM@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS1_k127_268925_0	1288298.rosmuc_01612	1.051e-118	383.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,46PGK@74030|Roseovarius	28211|Alphaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS1_k127_268925_2	89187.ISM_15580	6.329e-31	124.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,46NB9@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS1_k127_2690760_1	1354722.JQLS01000008_gene212	3.285e-117	386.0	COG0223@1|root,COG1020@1|root,COG2141@1|root,COG0223@2|Bacteria,COG1020@2|Bacteria,COG2141@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,46NBX@74030|Roseovarius	28211|Alphaproteobacteria	CJQ	Non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Formyl_trans_C,Formyl_trans_N,PP-binding
CMS1_k127_2690760_0	314264.ROS217_05059	2.142e-146	471.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2TRZB@28211|Alphaproteobacteria,46NJW@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase, group 2 family protein	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
CMS1_k127_2707770_4	391624.OIHEL45_05425	6.051e-154	487.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12369	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_2707770_3	52598.EE36_12258	1.059e-165	526.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria,3ZWAT@60136|Sulfitobacter	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	dppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_2707770_1	52598.EE36_12263	3.786e-185	581.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,3ZW2Z@60136|Sulfitobacter	28211|Alphaproteobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	dppD	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678	-	ko:K12371	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_2707770_2	52598.EE36_12268	2.17e-170	539.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,3ZVMP@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	dppF	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678	-	ko:K12372	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_2707770_0	391613.RTM1035_06668	0.0	1365.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,46Q15@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
CMS1_k127_271373_1	999547.KI421500_gene844	3.403e-163	516.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2TRW7@28211|Alphaproteobacteria,28072@191028|Leisingera	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	acuI	-	1.1.1.1	ko:K00001,ko:K19745	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R00919,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00095,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_271373_0	314264.ROS217_14471	1.171e-227	706.0	COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,46QD4@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the GcvT family	dmdA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259	2.1.1.269	ko:K17486	ko00920,map00920	-	R10333	RC00113,RC00347	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_271373_3	1354722.JQLS01000008_gene407	6.944e-129	412.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2TQPP@28211|Alphaproteobacteria,46PKG@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS1_k127_271373_2	314264.ROS217_14456	2.657e-130	419.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,46PG0@74030|Roseovarius	28211|Alphaproteobacteria	S	metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
CMS1_k127_271373_4	1354722.JQLS01000008_gene405	1.231e-125	405.0	COG2186@1|root,COG2186@2|Bacteria,1NXAS@1224|Proteobacteria,2V9ME@28211|Alphaproteobacteria,46P3C@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_2718136_3	314264.ROS217_18797	2.153e-54	195.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2TRWD@28211|Alphaproteobacteria,46Q5J@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0729 Outer membrane protein	tamA	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
CMS1_k127_2718136_0	1354722.JQLS01000008_gene1683	0.0	1702.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,46P18@74030|Roseovarius	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS1_k127_2718136_2	1354722.JQLS01000008_gene1682	4.089e-161	514.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,46NNA@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS1_k127_2718136_1	1354722.JQLS01000008_gene1681	3.137e-248	791.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TXXE@28211|Alphaproteobacteria,46PFF@74030|Roseovarius	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_2723093_1	1288298.rosmuc_03320	1.08e-161	509.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,46NC7@74030|Roseovarius	28211|Alphaproteobacteria	H	5-aminolevulinic acid synthase	hemA	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2723093_0	314264.ROS217_21732	8.148e-203	638.0	COG1426@1|root,COG1426@2|Bacteria,1MYWX@1224|Proteobacteria,2TQM2@28211|Alphaproteobacteria,46NP7@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CMS1_k127_2730380_1	391613.RTM1035_12643	3.167e-143	455.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria,46NDU@74030|Roseovarius	28211|Alphaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_2730380_2	1354722.JQLS01000008_gene2085	8.691e-123	400.0	COG1266@1|root,COG1266@2|Bacteria,1QSFU@1224|Proteobacteria,2U5DX@28211|Alphaproteobacteria,46NQ7@74030|Roseovarius	28211|Alphaproteobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_2730380_0	89187.ISM_08925	0.0	1042.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,46QGH@74030|Roseovarius	28211|Alphaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_2730380_3	1354722.JQLS01000008_gene2083	2.826e-16	81.0	2BMZ5@1|root,32GJ1@2|Bacteria,1MYYN@1224|Proteobacteria,2U99W@28211|Alphaproteobacteria,46QU8@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2738964_4	571166.KI421509_gene4034	6.42e-103	339.0	COG1396@1|root,COG1396@2|Bacteria,1MVQY@1224|Proteobacteria,2U070@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS1_k127_2738964_1	571166.KI421509_gene4033	3.338e-233	723.0	2DB9X@1|root,2Z7ZS@2|Bacteria,1N6CK@1224|Proteobacteria,2TUY7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3445)	-	-	1.14.13.238	ko:K22342	-	-	-	-	ko00000,ko01000	-	-	-	DUF3445
CMS1_k127_2738964_3	571166.KI421509_gene4032	1.059e-192	604.0	COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2TRE9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	yeaX	-	1.14.13.238	ko:K21832,ko:K22343	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS1_k127_2738964_5	391613.RTM1035_07654	1.422e-100	331.0	28IUB@1|root,2Z8T2@2|Bacteria,1N0PJ@1224|Proteobacteria,2U3CJ@28211|Alphaproteobacteria,46NV7@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	1.14.13.238	ko:K22344	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS1_k127_2738964_0	439496.RBY4I_3160	2.167e-234	732.0	COG0404@1|root,COG0404@2|Bacteria,1N1G4@1224|Proteobacteria,2TS47@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_2738964_2	1288298.rosmuc_03674	8.705e-202	629.0	COG0004@1|root,COG0004@2|Bacteria,1MX44@1224|Proteobacteria,2TR55@28211|Alphaproteobacteria,46PMJ@74030|Roseovarius	28211|Alphaproteobacteria	P	Ammonium transporter	amt	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
CMS1_k127_2759687_1	367336.OM2255_06975	8.676e-127	408.0	COG2218@1|root,COG2218@2|Bacteria,1MUUQ@1224|Proteobacteria,2TSRA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0070 Glutamate synthase domain 3	glxC	-	2.1.1.21	ko:K22082	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GXGXG
CMS1_k127_2759687_0	571166.KI421509_gene4021	3.098e-160	508.0	COG0034@1|root,COG0034@2|Bacteria,1MWHP@1224|Proteobacteria,2U06H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	glutamine amidotransferase	glxB	-	2.1.1.21	ko:K22081	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GATase_6
CMS1_k127_2759687_3	1288298.rosmuc_03673	1.459e-31	125.0	2E7A9@1|root,331TT@2|Bacteria,1NE46@1224|Proteobacteria,2UHHC@28211|Alphaproteobacteria,46R4G@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2759687_2	1002340.AFCF01000007_gene2896	1.48e-81	272.0	COG0004@1|root,COG0004@2|Bacteria,1MX44@1224|Proteobacteria,2TR55@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0004 Ammonia permease	amt	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
CMS1_k127_2766158_0	1354722.JQLS01000008_gene497	6.836e-270	832.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,46PW4@74030|Roseovarius	28211|Alphaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_2766158_3	314264.ROS217_04020	2.92e-33	130.0	COG3103@1|root,COG4991@2|Bacteria,1NBEU@1224|Proteobacteria,2UF8D@28211|Alphaproteobacteria,46QEE@74030|Roseovarius	28211|Alphaproteobacteria	T	COG3103 SH3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
CMS1_k127_2766158_1	1354722.JQLS01000008_gene495	6.602e-155	492.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria,46NHX@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	vdlC	GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2766158_4	1354722.JQLS01000008_gene494	4.045e-31	124.0	2E3XR@1|root,32YUS@2|Bacteria,1N8QN@1224|Proteobacteria,2UFB4@28211|Alphaproteobacteria,46R62@74030|Roseovarius	28211|Alphaproteobacteria	S	Hypoxia induced protein conserved region	-	-	-	-	-	-	-	-	-	-	-	-	HIG_1_N
CMS1_k127_2766158_2	1288298.rosmuc_02564	2.332e-104	341.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,46PUI@74030|Roseovarius	28211|Alphaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS1_k127_2771520_5	351016.RAZWK3B_01080	9.419e-20	89.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2U1Z7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Trap dicarboxylate transporter, dctm subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_2771520_4	351016.RAZWK3B_01085	1.902e-67	234.0	COG3090@1|root,COG3090@2|Bacteria,1RC6J@1224|Proteobacteria,2U58E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TRAP dicarboxylate transporter, DctQ subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_2771520_1	351016.RAZWK3B_01090	5.521e-179	565.0	COG1638@1|root,COG1638@2|Bacteria,1R7RA@1224|Proteobacteria,2TZ3M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Trap dicarboxylate transporter, dctp subunit	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
CMS1_k127_2771520_2	351016.RAZWK3B_01095	1.131e-140	454.0	COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,2TRGQ@28211|Alphaproteobacteria,2P25H@2433|Roseobacter	28211|Alphaproteobacteria	K	Transcriptional Regulator, LysR family protein	-	-	-	ko:K21645	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_2771520_3	1354722.JQLS01000008_gene2648	9.698e-128	413.0	COG1414@1|root,COG1414@2|Bacteria,1R5ZB@1224|Proteobacteria,2TUN3@28211|Alphaproteobacteria,46QK7@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1414 Transcriptional regulator	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
CMS1_k127_2771520_0	981384.AEYW01000001_gene1618	8.202e-230	714.0	COG1593@1|root,COG1593@2|Bacteria,1QNVU@1224|Proteobacteria,2U0UE@28211|Alphaproteobacteria,4NBWU@97050|Ruegeria	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
CMS1_k127_2772934_3	1469613.JT55_00195	2.246e-69	237.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_2772934_2	1354722.JQLS01000008_gene3270	7.363e-118	381.0	COG1280@1|root,COG1280@2|Bacteria,1RAI3@1224|Proteobacteria,2U7PZ@28211|Alphaproteobacteria,46NPC@74030|Roseovarius	28211|Alphaproteobacteria	E	LysE type translocator	leuE	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_2772934_0	1354722.JQLS01000008_gene3271	0.0	1516.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,46QB6@74030|Roseovarius	28211|Alphaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_2772934_1	1041139.KB902691_gene1032	1.814e-118	394.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,2TTA9@28211|Alphaproteobacteria,4BD1C@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2780705_3	314271.RB2654_06314	8.698e-108	353.0	COG2271@1|root,COG2271@2|Bacteria,1QVY6@1224|Proteobacteria,2TWTV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2780705_5	314270.RB2083_3109	9.909e-29	117.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,3ZI0U@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
CMS1_k127_2780705_6	1268068.PG5_01420	1.681e-05	48.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS1_k127_2780705_0	1354722.JQLS01000008_gene2120	1.139e-269	840.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,46PEY@74030|Roseovarius	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_2780705_4	314264.ROS217_15720	7.853e-106	348.0	COG2197@1|root,COG2197@2|Bacteria,1REG5@1224|Proteobacteria,2U8UP@28211|Alphaproteobacteria,46QEU@74030|Roseovarius	28211|Alphaproteobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	sgaR	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_2780705_1	314264.ROS217_15715	2.342e-228	712.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,46Q0R@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	sgaA	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_2780705_2	1354722.JQLS01000008_gene2117	1.986e-151	486.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TU4H@28211|Alphaproteobacteria,46QCQ@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_2799314_1	1288298.rosmuc_02605	3.166e-131	425.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2TSA1@28211|Alphaproteobacteria,46QBP@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_2799314_0	1288298.rosmuc_02606	1.48e-223	697.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,2TR3A@28211|Alphaproteobacteria,46Q5U@74030|Roseovarius	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	hutF	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS1_k127_2802939_1	1354722.JQLS01000008_gene1013	4.575e-114	370.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,46PTU@74030|Roseovarius	28211|Alphaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS1_k127_2802939_0	1354722.JQLS01000008_gene1012	2.655e-136	440.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,46NPX@74030|Roseovarius	28211|Alphaproteobacteria	J	SpoU rRNA Methylase family	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF559,SpoU_methylase
CMS1_k127_2802939_3	391619.PGA1_c19870	4.023e-52	192.0	COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria,34EHU@302485|Phaeobacter	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4167
CMS1_k127_2802939_2	644107.SL1157_2628	2.489e-93	314.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,4NAAZ@97050|Ruegeria	28211|Alphaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS1_k127_2837083_0	1354722.JQLS01000008_gene3684	4.702e-257	795.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,46NW5@74030|Roseovarius	28211|Alphaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS1_k127_2837083_8	1354722.JQLS01000008_gene3683	6.36e-120	390.0	COG3217@1|root,COG3217@2|Bacteria,1MVSP@1224|Proteobacteria,2U1ST@28211|Alphaproteobacteria,46P2U@74030|Roseovarius	28211|Alphaproteobacteria	S	MOSC domain protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
CMS1_k127_2837083_9	1354722.JQLS01000008_gene3682	9.026e-119	385.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,46PBK@74030|Roseovarius	28211|Alphaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS1_k127_2837083_6	351016.RAZWK3B_03915	4.982e-159	504.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,2P1X2@2433|Roseobacter	28211|Alphaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS1_k127_2837083_7	89187.ISM_05295	1.119e-128	416.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,46QNX@74030|Roseovarius	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_2837083_10	1354722.JQLS01000008_gene2823	3.655e-93	310.0	COG1600@1|root,COG1600@2|Bacteria,1R9XX@1224|Proteobacteria,2UA5Q@28211|Alphaproteobacteria,46P90@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1145 Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2837083_11	314264.ROS217_12696	4.933e-62	218.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,46QQ1@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2062 Phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS1_k127_2837083_4	1288298.rosmuc_02171	2.227e-198	623.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRGU@28211|Alphaproteobacteria,46QI8@74030|Roseovarius	28211|Alphaproteobacteria	BQ	Including yeast histone deacetylase and acetoin utilization protein	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
CMS1_k127_2837083_5	1354722.JQLS01000008_gene2825	1.297e-159	506.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,46NW2@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1126 ABC-type polar amino acid transport system, ATPase component	bztD	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
CMS1_k127_2837083_1	314264.ROS217_12681	1.393e-247	767.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,46PS3@74030|Roseovarius	28211|Alphaproteobacteria	P	Glutamate glutamine aspartate asparagine ABC transporter, permease protein	bztC	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
CMS1_k127_2837083_2	314264.ROS217_12676	1.062e-225	705.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,46NU5@74030|Roseovarius	28211|Alphaproteobacteria	P	COG4597 ABC-type amino acid transport system, permease component	bztB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
CMS1_k127_2837083_3	1354722.JQLS01000008_gene2828	2.018e-202	632.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,46PC7@74030|Roseovarius	28211|Alphaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	bztA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
CMS1_k127_2848892_7	391613.RTM1035_13578	3.06e-40	151.0	COG0741@1|root,COG0741@2|Bacteria,1N5Z6@1224|Proteobacteria,2U1GR@28211|Alphaproteobacteria,46P8X@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_2848892_2	1288298.rosmuc_01941	2.699e-224	700.0	28IK2@1|root,2Z8KV@2|Bacteria,1PEUQ@1224|Proteobacteria,2U38Z@28211|Alphaproteobacteria,46NCD@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2848892_4	314264.ROS217_13846	2.367e-143	460.0	COG4977@1|root,COG4977@2|Bacteria,1PMRY@1224|Proteobacteria,2U2QN@28211|Alphaproteobacteria,46NFX@74030|Roseovarius	28211|Alphaproteobacteria	K	COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
CMS1_k127_2848892_3	1288298.rosmuc_02414	3.087e-178	560.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria,46QI2@74030|Roseovarius	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	kce	-	-	-	-	-	-	-	-	-	-	-	BKACE
CMS1_k127_2848892_5	351016.RAZWK3B_06507	3.933e-122	396.0	COG1028@1|root,COG1028@2|Bacteria,1MX30@1224|Proteobacteria,2TR09@28211|Alphaproteobacteria,2P256@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	linC	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2848892_6	1380367.JIBC01000006_gene339	4.973e-46	173.0	COG3040@1|root,COG3040@2|Bacteria,1N9IU@1224|Proteobacteria,2UFT3@28211|Alphaproteobacteria,3ZZCX@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
CMS1_k127_2848892_0	1354722.JQLS01000008_gene374	7.307e-274	846.0	COG0824@1|root,COG1250@1|root,COG0824@2|Bacteria,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,46P0Y@74030|Roseovarius	28211|Alphaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine	lcdH	-	1.1.1.108	ko:K17735	-	-	-	-	ko00000,ko01000	-	-	-	3HCDH,3HCDH_N,4HBT_2
CMS1_k127_2848892_1	246200.SPOA0288	2.625e-238	739.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,4N9XJ@97050|Ruegeria	28211|Alphaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	acdA	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2853844_3	89187.ISM_14300	6.22e-129	412.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,46PBX@74030|Roseovarius	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS1_k127_2853844_7	1288298.rosmuc_01511	1.505e-45	167.0	2ENBT@1|root,33FZE@2|Bacteria,1NN88@1224|Proteobacteria,2UMMZ@28211|Alphaproteobacteria,46R0C@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2853844_4	1354722.JQLS01000008_gene1529	5.812e-102	341.0	2AE28@1|root,313V2@2|Bacteria,1PT3D@1224|Proteobacteria,2V51W@28211|Alphaproteobacteria,46PTX@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2853844_10	1354722.JQLS01000008_gene1528	2.308e-33	130.0	2ECZZ@1|root,336WZ@2|Bacteria,1N8TI@1224|Proteobacteria,2UFIW@28211|Alphaproteobacteria,46R7H@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2853844_2	1354722.JQLS01000008_gene1527	5.265e-204	639.0	COG1905@1|root,COG3743@1|root,COG1905@2|Bacteria,COG3743@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,46NDW@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1905 NADH ubiquinone oxidoreductase 24 kD subunit	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
CMS1_k127_2853844_5	391613.RTM1035_08614	7.665e-75	256.0	COG3743@1|root,COG3743@2|Bacteria,1N76A@1224|Proteobacteria,2U93Q@28211|Alphaproteobacteria,46QFF@74030|Roseovarius	28211|Alphaproteobacteria	S	NADH ubiquinone oxidoreductase 41 kD complex I subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2853844_9	391613.RTM1035_08609	1.567e-35	139.0	2E3P6@1|root,32YM9@2|Bacteria,1N8AJ@1224|Proteobacteria,2UFGM@28211|Alphaproteobacteria,46R59@74030|Roseovarius	28211|Alphaproteobacteria	S	Family of unknown function (DUF5337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5337
CMS1_k127_2853844_1	1288298.rosmuc_01517	1.04e-291	895.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria,46PCX@74030|Roseovarius	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_2853844_6	1354722.JQLS01000008_gene1523	2.19e-46	171.0	2E36G@1|root,32Y67@2|Bacteria,1NE0K@1224|Proteobacteria,2UG0I@28211|Alphaproteobacteria,46QZ0@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2853844_8	1305735.JAFT01000005_gene2980	9.979e-41	154.0	2E5WE@1|root,330KF@2|Bacteria,1N9NQ@1224|Proteobacteria,2UHY3@28211|Alphaproteobacteria,2PEK9@252301|Oceanicola	28211|Alphaproteobacteria	S	Family of unknown function (DUF5333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5333
CMS1_k127_2853844_0	1354722.JQLS01000008_gene1521	0.0	1217.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,46PER@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
CMS1_k127_2853844_11	1354722.JQLS01000008_gene1520	6.002e-25	109.0	2ANT7@1|root,31DTG@2|Bacteria,1RHPB@1224|Proteobacteria,2U9BN@28211|Alphaproteobacteria,46QZD@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2869520_2	1354722.JQLS01000008_gene597	9.318e-81	271.0	2CKJA@1|root,2Z7YS@2|Bacteria,1NBXM@1224|Proteobacteria,2TV3D@28211|Alphaproteobacteria,46PNK@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2869520_1	571166.KI421509_gene4161	1.678e-296	917.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_2869520_0	1380367.JIBC01000004_gene2336	5.072e-299	919.0	COG0446@1|root,COG3453@1|root,COG0446@2|Bacteria,COG3453@2|Bacteria,1N5MC@1224|Proteobacteria,2TW6Z@28211|Alphaproteobacteria,3ZUWP@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Putative phosphatase (DUF442)	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442,Pyr_redox_2
CMS1_k127_2874565_1	1354722.JQLS01000008_gene858	0.0	1023.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,46PCR@74030|Roseovarius	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_2874565_0	391613.RTM1035_12358	0.0	1076.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,46P8R@74030|Roseovarius	28211|Alphaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS1_k127_2874565_4	314264.ROS217_17152	1.276e-22	100.0	2EN9C@1|root,33FX6@2|Bacteria,1NJ95@1224|Proteobacteria,2UMJY@28211|Alphaproteobacteria,46R7R@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2874565_3	439496.RBY4I_247	1.909e-68	239.0	COG4583@1|root,COG4583@2|Bacteria,1RC66@1224|Proteobacteria,2U5RU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Sarcosine oxidase, gamma subunit	soxGe	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
CMS1_k127_2874565_2	1354722.JQLS01000008_gene854	2.085e-197	619.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,46NNR@74030|Roseovarius	28211|Alphaproteobacteria	C	Sarcosine oxidase, alpha subunit family protein	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_287539_11	246200.SPO1114	2.095e-36	138.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,4ND4X@97050|Ruegeria	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_287539_6	1354722.JQLS01000008_gene3515	8.83e-117	385.0	COG0385@1|root,COG0385@2|Bacteria,1MVXH@1224|Proteobacteria,2TTE0@28211|Alphaproteobacteria,46QIV@74030|Roseovarius	28211|Alphaproteobacteria	S	Bile acid	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS1_k127_287539_1	1354722.JQLS01000008_gene3103	6.719e-249	774.0	COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2U0IN@28211|Alphaproteobacteria,46PGE@74030|Roseovarius	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	codA	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
CMS1_k127_287539_3	391613.RTM1035_17895	2.174e-176	562.0	COG1079@1|root,COG1079@2|Bacteria,1NAYV@1224|Proteobacteria,2TTM0@28211|Alphaproteobacteria,46NMI@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS1_k127_287539_8	639283.Snov_2306	1.064e-100	340.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TUGD@28211|Alphaproteobacteria,3F297@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS1_k127_287539_0	1354722.JQLS01000008_gene3100	1.768e-274	850.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2UPJ8@28211|Alphaproteobacteria,46Q0F@74030|Roseovarius	28211|Alphaproteobacteria	P	ABC sugar transporter, fused ATPase	rbsA4	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
CMS1_k127_287539_2	314264.ROS217_10977	2.045e-190	598.0	COG1744@1|root,COG1744@2|Bacteria,1MVU5@1224|Proteobacteria,2TTTH@28211|Alphaproteobacteria,46NR0@74030|Roseovarius	28211|Alphaproteobacteria	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
CMS1_k127_287539_9	391613.RTM1035_17840	2.748e-90	304.0	COG0500@1|root,COG0500@2|Bacteria,1QYR8@1224|Proteobacteria,2TXX8@28211|Alphaproteobacteria,46NRH@74030|Roseovarius	28211|Alphaproteobacteria	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_287539_7	314264.ROS217_11022	5.298e-114	371.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria,46NDE@74030|Roseovarius	28211|Alphaproteobacteria	P	COG4662 ABC-type tungstate transport system, periplasmic component	MA20_34300	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
CMS1_k127_287539_10	1469245.JFBG01000038_gene1806	1.69e-87	296.0	COG1117@1|root,COG1117@2|Bacteria	2|Bacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	pstB	-	3.6.3.27,3.6.3.55	ko:K02036,ko:K06857	ko02010,map02010	M00186,M00222	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.7	-	-	ABC_tran
CMS1_k127_287539_4	314264.ROS217_11032	1.99e-145	464.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2TU33@28211|Alphaproteobacteria,46NNP@74030|Roseovarius	28211|Alphaproteobacteria	P	Sulfate tungstate uptake family ABC transporter, periplasmic substrate-binding protein	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
CMS1_k127_287539_5	1354722.JQLS01000008_gene3089	1.746e-124	405.0	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,2TU96@28211|Alphaproteobacteria,46Q08@74030|Roseovarius	28211|Alphaproteobacteria	P	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
CMS1_k127_2887185_0	1354722.JQLS01000008_gene2047	4.926e-104	339.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,46NJG@74030|Roseovarius	28211|Alphaproteobacteria	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	msbA2	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2887185_2	1354722.JQLS01000008_gene2046	1.286e-55	195.0	2C7TH@1|root,32RJS@2|Bacteria,1MZK8@1224|Proteobacteria,2UC2R@28211|Alphaproteobacteria,46QYE@74030|Roseovarius	28211|Alphaproteobacteria	C	ETC complex I subunit conserved region	MA20_30235	-	1.6.5.3	ko:K00329	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	ETC_C1_NDUFA4
CMS1_k127_2887185_1	1461693.ATO10_11832	1.621e-95	315.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polyphosphate kinase	ppk2	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
CMS1_k127_2891003_2	314264.ROS217_11052	1.856e-187	587.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,2TT29@28211|Alphaproteobacteria,46P98@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0006 Xaa-Pro aminopeptidase	eutD	-	3.4.13.9,3.5.4.44	ko:K01271,ko:K15783	ko00260,ko01100,map00260,map01100	-	R09800	RC02661	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_2891003_3	1354722.JQLS01000008_gene3085	2.744e-177	562.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,46Q4C@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1171 Threonine dehydratase	eutB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2891003_4	1208323.B30_10350	2.64e-136	440.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2TT7X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ornithine cyclodeaminase	eutC	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS1_k127_2891003_5	1354722.JQLS01000008_gene3082	3.167e-89	295.0	COG1522@1|root,COG1522@2|Bacteria,1RH5M@1224|Proteobacteria,2UAXN@28211|Alphaproteobacteria,46NSM@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, AsnC family	-	-	-	ko:K15782	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_2891003_0	1354722.JQLS01000008_gene3081	1.726e-281	870.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46NPI@74030|Roseovarius	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	gabD6	-	-	ko:K15786	ko00260,map00260	-	R09805	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_2891003_1	1354722.JQLS01000008_gene3080	2.974e-274	847.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,46NQ3@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K15785	ko00260,map00260	-	R06977	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
CMS1_k127_2891003_6	314264.ROS217_11082	1.759e-14	73.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,46PQI@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
CMS1_k127_2917739_2	1354722.JQLS01000008_gene1531	7.168e-131	417.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,46PBX@74030|Roseovarius	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS1_k127_2917739_8	1354722.JQLS01000008_gene1532	1.016e-31	124.0	2DNSA@1|root,32YWR@2|Bacteria,1NDGB@1224|Proteobacteria,2UGZV@28211|Alphaproteobacteria,46RZM@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2917739_3	1354722.JQLS01000008_gene1533	3.015e-118	383.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,46Q0H@74030|Roseovarius	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS1_k127_2917739_6	391613.RTM1035_08649	8.268e-113	364.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria,46NMV@74030|Roseovarius	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS1_k127_2917739_7	59538.XP_005973860.1	5.159e-46	169.0	COG0838@1|root,KOG4662@2759|Eukaryota,3A8AU@33154|Opisthokonta	33154|Opisthokonta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad3	-	1.6.5.3	ko:K03880	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q4
CMS1_k127_2917739_1	1354722.JQLS01000008_gene1536	4.747e-135	434.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,46NIA@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_2917739_0	314264.ROS217_20777	6.528e-152	484.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,46QJX@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0119 Isopropylmalate homocitrate citramalate synthases	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS1_k127_2917739_4	351016.RAZWK3B_13314	5.035e-115	373.0	COG0625@1|root,COG0625@2|Bacteria,1PA0Q@1224|Proteobacteria,2TVIC@28211|Alphaproteobacteria,2P1Z1@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0625 Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
CMS1_k127_2917739_5	314264.ROS217_20792	4.221e-114	373.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,46NNW@74030|Roseovarius	28211|Alphaproteobacteria	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	mccA	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_2923497_0	1123360.thalar_01173	2.051e-294	905.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	MA20_40290	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_2923497_1	1342299.Z947_2088	5.884e-259	803.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TUDG@28211|Alphaproteobacteria,3ZWSH@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_2923497_3	83219.PM02_00010	2.846e-90	302.0	COG1396@1|root,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,2TU8R@28211|Alphaproteobacteria,3ZX91@60136|Sulfitobacter	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS1_k127_2923497_2	1288298.rosmuc_00335	9.177e-98	325.0	COG3971@1|root,COG3971@2|Bacteria,1RA35@1224|Proteobacteria,2U7JG@28211|Alphaproteobacteria,46P2D@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG3971 2-keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS1_k127_2923497_4	1288298.rosmuc_00336	2.177e-77	260.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,46PU9@74030|Roseovarius	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_2937680_3	391613.RTM1035_15697	1.636e-87	290.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TT7Y@28211|Alphaproteobacteria,46PA7@74030|Roseovarius	28211|Alphaproteobacteria	GM	And related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2937680_2	1288298.rosmuc_02644	7.732e-124	405.0	COG0489@1|root,COG0489@2|Bacteria,1MWQC@1224|Proteobacteria,2TXN9@28211|Alphaproteobacteria,46NB5@74030|Roseovarius	28211|Alphaproteobacteria	D	Exopolysaccharide biosynthesis domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,ParA
CMS1_k127_2937680_1	1288298.rosmuc_02617	2.198e-164	529.0	COG3206@1|root,COG3206@2|Bacteria,1R7FS@1224|Proteobacteria,2VEXP@28211|Alphaproteobacteria,46QGT@74030|Roseovarius	28211|Alphaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
CMS1_k127_2937680_4	1354722.JQLS01000008_gene211	3.849e-65	230.0	COG2977@1|root,COG2977@2|Bacteria,1MZK2@1224|Proteobacteria,2U22J@28211|Alphaproteobacteria,46N9P@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG2977 Phosphopantetheinyl transferase component of siderophore synthetase	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
CMS1_k127_2937680_0	314264.ROS217_05064	0.0	1843.0	COG0223@1|root,COG1020@1|root,COG2141@1|root,COG0223@2|Bacteria,COG1020@2|Bacteria,COG2141@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,46NBX@74030|Roseovarius	28211|Alphaproteobacteria	CJQ	Non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Formyl_trans_C,Formyl_trans_N,PP-binding
CMS1_k127_2943150_0	391613.RTM1035_13138	7.415e-152	483.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,46QCP@74030|Roseovarius	28211|Alphaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS1_k127_2943150_2	1288298.rosmuc_02004	3.683e-94	310.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,46PM8@74030|Roseovarius	28211|Alphaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS1_k127_2943150_3	1342302.JASC01000014_gene1052	7.969e-65	226.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2U945@28211|Alphaproteobacteria,3ZXGV@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_2943150_4	1354722.JQLS01000008_gene859	1.558e-28	118.0	COG5453@1|root,COG5453@2|Bacteria,1N7WA@1224|Proteobacteria,2UFN1@28211|Alphaproteobacteria,46R15@74030|Roseovarius	28211|Alphaproteobacteria	S	Transcriptional activator HlyU	hlyU	-	-	-	-	-	-	-	-	-	-	-	HlyU
CMS1_k127_2943150_1	1354722.JQLS01000008_gene858	2.011e-102	334.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,46PCR@74030|Roseovarius	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_2974347_0	314264.ROS217_17142	5.947e-311	961.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,46NNR@74030|Roseovarius	28211|Alphaproteobacteria	C	Sarcosine oxidase, alpha subunit family protein	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_2974347_3	89187.ISM_12985	5.267e-39	147.0	COG4311@1|root,COG4311@2|Bacteria,1N8ED@1224|Proteobacteria,2UFIN@28211|Alphaproteobacteria,46R33@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4311 Sarcosine oxidase delta subunit	soxD_2	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
CMS1_k127_2974347_2	1288298.rosmuc_03151	2.561e-250	775.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,46N9G@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	soxB1	-	1.5.3.1,1.5.99.5	ko:K00303,ko:K22084	ko00260,ko00680,ko01100,ko01120,map00260,map00680,map01100,map01120	-	R00609,R00610	RC00060,RC00190,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_2974347_1	1354722.JQLS01000008_gene851	7.824e-264	815.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,46PWY@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_297783_0	351016.RAZWK3B_11111	1.176e-259	802.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2P15J@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_297783_1	1288298.rosmuc_02967	9.509e-85	287.0	COG1309@1|root,COG1309@2|Bacteria,1RG02@1224|Proteobacteria,2U86G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_297783_2	1288298.rosmuc_02968	1.557e-82	276.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2U7JU@28211|Alphaproteobacteria,46S12@74030|Roseovarius	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
CMS1_k127_2980693_1	1288298.rosmuc_00535	1.316e-162	514.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,46PEI@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_2980693_0	391613.RTM1035_16967	2.378e-250	776.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria,46PTE@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	tauC	-	-	ko:K15552	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
CMS1_k127_2980693_2	391613.RTM1035_16962	1.064e-136	436.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,46PEG@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system	tauB	GO:0003674,GO:0003824,GO:0005215,GO:0005342,GO:0005368,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0008559,GO:0015075,GO:0015238,GO:0015399,GO:0015405,GO:0015411,GO:0015711,GO:0015734,GO:0015849,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033283,GO:0034220,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042908,GO:0042910,GO:0043492,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:0098656,GO:1901682,GO:1903825	3.6.3.36	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
CMS1_k127_2983737_2	1123247.AUIJ01000004_gene1158	4.609e-108	355.0	COG0331@1|root,COG0331@2|Bacteria,1MW5Y@1224|Proteobacteria,2TT74@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-carrier-protein s-malonyltransferase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
CMS1_k127_2983737_0	1354722.JQLS01000008_gene944	4.167e-285	880.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46NUS@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_2983737_1	1041147.AUFB01000008_gene859	7.95e-111	370.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,4BBA4@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Oxidoreductase	ordL	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_2986508_2	1288298.rosmuc_01356	6.695e-25	107.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,46P9C@74030|Roseovarius	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	nahG	-	1.14.13.1	ko:K00480	ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
CMS1_k127_2986508_1	1354722.JQLS01000008_gene1600	7.262e-83	276.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,46PR6@74030|Roseovarius	28211|Alphaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS1_k127_2986508_0	1354722.JQLS01000008_gene1601	3.824e-122	394.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria,46Q3E@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0714 MoxR-like ATPases	MA20_01295	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS1_k127_299160_2	571166.KI421509_gene788	3.137e-104	338.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VEY7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0437 Fe-S-cluster-containing hydrogenase components 1	fdhB	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4,Fer4_11,Fer4_7
CMS1_k127_299160_1	314264.ROS217_14431	2.276e-216	676.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2TT30@28211|Alphaproteobacteria,46PD6@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2864 Cytochrome b subunit of formate dehydrogenase	fdnI	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
CMS1_k127_299160_0	314264.ROS217_14436	7.825e-227	709.0	COG2319@1|root,COG3474@1|root,COG2319@2|Bacteria,COG3474@2|Bacteria,1MWJA@1224|Proteobacteria,2TRIX@28211|Alphaproteobacteria,46N9D@74030|Roseovarius	28211|Alphaproteobacteria	C	WD domain cytochrome c family protein	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,WD40
CMS1_k127_299160_4	1288298.rosmuc_02457	1.922e-11	65.0	2ACXJ@1|root,312J5@2|Bacteria,1PQTI@1224|Proteobacteria,2V35D@28211|Alphaproteobacteria,46RA3@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_299160_3	1354722.JQLS01000008_gene404	1.263e-40	151.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,46NNC@74030|Roseovarius	28211|Alphaproteobacteria	T	Containing CheY-like receiver, AAA-type ATPase, and DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3010336_3	1354722.JQLS01000008_gene1413	4.621e-29	118.0	COG2897@1|root,COG2897@2|Bacteria,1P6SN@1224|Proteobacteria,2TVFJ@28211|Alphaproteobacteria,46PW3@74030|Roseovarius	28211|Alphaproteobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_3010336_1	351016.RAZWK3B_13884	1.245e-107	354.0	COG2267@1|root,COG2267@2|Bacteria,1RG43@1224|Proteobacteria,2U6MB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3010336_2	1500301.JQMF01000011_gene2479	8.376e-75	256.0	28I63@1|root,2Z897@2|Bacteria,1N3VY@1224|Proteobacteria,2TTW0@28211|Alphaproteobacteria,4BAPU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amino acid synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AA_synth
CMS1_k127_3010336_0	391613.RTM1035_04920	3.82e-208	649.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TV8M@28211|Alphaproteobacteria,46NRV@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	limB	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_3045673_3	314264.ROS217_22387	0.0003718	44.0	COG2267@1|root,COG2267@2|Bacteria,1QUPE@1224|Proteobacteria,2TT7G@28211|Alphaproteobacteria,46QIB@74030|Roseovarius	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	bchO	-	-	ko:K06049	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3045673_2	314264.ROS217_22387	8.472e-08	55.0	COG2267@1|root,COG2267@2|Bacteria,1QUPE@1224|Proteobacteria,2TT7G@28211|Alphaproteobacteria,46QIB@74030|Roseovarius	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	bchO	-	-	ko:K06049	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3045673_0	351016.RAZWK3B_15023	7.537e-127	412.0	COG0583@1|root,COG0583@2|Bacteria,1RCQR@1224|Proteobacteria,2TV2A@28211|Alphaproteobacteria,2P35P@2433|Roseobacter	28211|Alphaproteobacteria	K	Transcriptional Regulator, LysR family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3045673_1	1002340.AFCF01000052_gene1584	1.711e-119	389.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,34F5M@302485|Phaeobacter	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_3057582_0	1354722.JQLS01000008_gene1886	5.602e-165	524.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,46P89@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3057582_3	1354722.JQLS01000008_gene1887	8.643e-116	382.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,2TVXP@28211|Alphaproteobacteria,46NGY@74030|Roseovarius	28211|Alphaproteobacteria	P	COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS1_k127_3057582_4	633131.TR2A62_1984	1.071e-54	197.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2U9G4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the Fur family	zur	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
CMS1_k127_3057582_1	1354722.JQLS01000008_gene1889	1.938e-131	422.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,46NEQ@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
CMS1_k127_3057582_2	1288298.rosmuc_02962	1.029e-123	401.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2TS2V@28211|Alphaproteobacteria,46PBV@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1108 ABC-type Mn2 Zn2 transport systems, permease components	znuB	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS1_k127_3063578_0	670292.JH26_03575	1.132e-270	838.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2TVQ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
CMS1_k127_3063578_2	391613.RTM1035_06403	1.326e-110	361.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2TSRT@28211|Alphaproteobacteria,46NHP@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	MA20_22545	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_3063578_3	388739.RSK20926_03654	3.542e-108	355.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSWS@28211|Alphaproteobacteria,2P1CX@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_3063578_1	1123247.AUIJ01000001_gene1844	1.989e-165	525.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TSID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_3063578_4	1354722.JQLS01000008_gene693	2.109e-20	91.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TSCF@28211|Alphaproteobacteria,46PDH@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_3083800_0	391613.RTM1035_17002	1.466e-156	500.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TUPD@28211|Alphaproteobacteria,46QIH@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529,ko:K06145	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_3105052_6	351016.RAZWK3B_19741	3.05e-15	76.0	28MU9@1|root,2ZB26@2|Bacteria,1N48H@1224|Proteobacteria,2UCZC@28211|Alphaproteobacteria,2P3MR@2433|Roseobacter	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3726
CMS1_k127_3105052_0	351016.RAZWK3B_19736	1.507e-291	904.0	COG4367@1|root,COG4367@2|Bacteria,1MU6T@1224|Proteobacteria,2TR0D@28211|Alphaproteobacteria,2P10N@2433|Roseobacter	28211|Alphaproteobacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3105052_5	351016.RAZWK3B_19731	6.98e-31	124.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,2TTTG@28211|Alphaproteobacteria,2P1NB@2433|Roseobacter	28211|Alphaproteobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	-	-	-	-	-	-	-	-	-	BCCT
CMS1_k127_3105052_2	351016.RAZWK3B_19726	5.148e-193	605.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2P0Z9@2433|Roseobacter	28211|Alphaproteobacteria	E	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS1_k127_3105052_1	1002340.AFCF01000064_gene147	1.187e-270	838.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,34G8D@302485|Phaeobacter	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_3105052_3	351016.RAZWK3B_19716	1.7e-125	407.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,2TU0X@28211|Alphaproteobacteria,2P31D@2433|Roseobacter	28211|Alphaproteobacteria	K	COG0583 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3105052_4	391613.RTM1035_13673	2.712e-59	206.0	COG4160@1|root,COG4160@2|Bacteria,1N189@1224|Proteobacteria,2TSWV@28211|Alphaproteobacteria,46PJA@74030|Roseovarius	28211|Alphaproteobacteria	P	Polar amino acid uptake family ABC transporter, permease protein	occM	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_3109523_1	1300350.DSW25_01000	9.327e-69	237.0	COG1121@1|root,COG1121@2|Bacteria,1MW47@1224|Proteobacteria,2TRJA@28211|Alphaproteobacteria,3ZVUR@60136|Sulfitobacter	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	sitB	-	-	ko:K11607,ko:K11710	ko02010,map02010	M00317,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
CMS1_k127_3109523_0	1300350.DSW25_00995	5.425e-151	481.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2TQTF@28211|Alphaproteobacteria,3ZW4P@60136|Sulfitobacter	28211|Alphaproteobacteria	P	Zinc-uptake complex component A periplasmic	sitA	-	-	ko:K02077,ko:K09815,ko:K11604	ko02010,map02010	M00242,M00244,M00317	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.A.1.15.7,3.A.1.15.9	-	-	ZnuA
CMS1_k127_3112081_0	1288298.rosmuc_00834	1.641e-148	474.0	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria,2TT4R@28211|Alphaproteobacteria,46PSJ@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2200 FOG EAL domain	yfgF	-	-	-	-	-	-	-	-	-	-	-	EAL
CMS1_k127_3112081_1	1288298.rosmuc_00833	2.405e-109	355.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,46QCR@74030|Roseovarius	28211|Alphaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS1_k127_3112081_2	644107.SL1157_1383	2.667e-71	244.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria,4N9WI@97050|Ruegeria	28211|Alphaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_3115628_2	999611.KI421504_gene363	2.618e-39	155.0	2B214@1|root,31UHY@2|Bacteria,1RJXN@1224|Proteobacteria,2U9RS@28211|Alphaproteobacteria,280CC@191028|Leisingera	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3115628_1	999547.KI421500_gene3183	4.197e-113	368.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,280IF@191028|Leisingera	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_3115628_0	1288298.rosmuc_03663	6.205e-130	416.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,46P8D@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_3122201_0	314264.ROS217_14951	9.354e-291	895.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,46PC5@74030|Roseovarius	28211|Alphaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	betC	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,DUF4976,Sulfatase
CMS1_k127_3122201_1	1288298.rosmuc_02807	2.524e-62	215.0	COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,2U5RY@28211|Alphaproteobacteria,46Q19@74030|Roseovarius	28211|Alphaproteobacteria	K	Repressor involved in choline regulation of the bet genes	betI	-	-	ko:K02167	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_6,TetR_N
CMS1_k127_3124503_0	1354722.JQLS01000008_gene1105	7.572e-292	897.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TRCP@28211|Alphaproteobacteria,46NAV@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0174 Glutamine synthetase	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
CMS1_k127_3124503_1	314264.ROS217_18307	2.09e-112	365.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,46QDK@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	ordL	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
CMS1_k127_3128868_3	1288298.rosmuc_02975	2.332e-68	238.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2V6JN@28211|Alphaproteobacteria,46QKC@74030|Roseovarius	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_3128868_0	1288298.rosmuc_02974	5.646e-319	982.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,46Q4D@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_3128868_1	1288298.rosmuc_02973	2.455e-290	896.0	COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,2TVGQ@28211|Alphaproteobacteria,46NYU@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN
CMS1_k127_3128868_2	1288298.rosmuc_02972	9.689e-236	734.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,46PUH@74030|Roseovarius	28211|Alphaproteobacteria	S	related to deoxyribodipyrimidine photolyase	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
CMS1_k127_3133447_3	314264.ROS217_13306	5.171e-51	183.0	COG0697@1|root,COG0697@2|Bacteria,1MY2U@1224|Proteobacteria,2TV71@28211|Alphaproteobacteria,46NTG@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
CMS1_k127_3133447_1	1305735.JAFT01000005_gene1830	8.687e-97	322.0	COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,2PD1G@252301|Oceanicola	28211|Alphaproteobacteria	G	Inositol monophosphatase family	suhB2	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_3133447_0	1354722.JQLS01000008_gene294	9.144e-239	745.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria,46ND2@74030|Roseovarius	28211|Alphaproteobacteria	S	Zn-dependent proteases and their inactivated homologs	pmbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_3133447_2	1288298.rosmuc_02327	8.59e-94	313.0	COG2982@1|root,COG2982@2|Bacteria,1MY1T@1224|Proteobacteria,2TS9U@28211|Alphaproteobacteria,46NEH@74030|Roseovarius	28211|Alphaproteobacteria	M	Uncharacterized protein conserved in bacteria (DUF2125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2125
CMS1_k127_3148112_0	1354722.JQLS01000008_gene992	8.708e-149	474.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,46PCN@74030|Roseovarius	28211|Alphaproteobacteria	O	COG1073 Hydrolases of the alpha beta superfamily	MA20_16590	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
CMS1_k127_3148112_2	1354722.JQLS01000008_gene1858	8.944e-57	199.0	COG0784@1|root,COG0784@2|Bacteria,1Q44V@1224|Proteobacteria,2VAKS@28211|Alphaproteobacteria,46S08@74030|Roseovarius	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3148112_1	1354722.JQLS01000008_gene1859	3.07e-57	210.0	COG5469@1|root,COG5469@2|Bacteria,1RIBJ@1224|Proteobacteria,2UADU@28211|Alphaproteobacteria,46QY2@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1636)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1636
CMS1_k127_3148112_3	1288298.rosmuc_03248	2.511e-44	169.0	COG0079@1|root,COG0079@2|Bacteria,1MXDP@1224|Proteobacteria,2TUEC@28211|Alphaproteobacteria,46NGN@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase	cobC	-	-	ko:K02225	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002	-	-	-	Aminotran_1_2
CMS1_k127_314896_12	1354722.JQLS01000008_gene1506	9.483e-36	138.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,46P64@74030|Roseovarius	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS1_k127_314896_13	1354722.JQLS01000008_gene1507	1.749e-07	55.0	2AD23@1|root,312Q9@2|Bacteria,1PR24@1224|Proteobacteria,2V3DG@28211|Alphaproteobacteria,46RBY@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_314896_3	391613.RTM1035_08519	2.101e-213	666.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TS06@28211|Alphaproteobacteria,46P27@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	aspB	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_314896_2	314264.ROS217_20627	7.22e-219	686.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,46NQN@74030|Roseovarius	28211|Alphaproteobacteria	S	Zn-dependent protease, contains TPR repeats	MA20_29180	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
CMS1_k127_314896_7	1354722.JQLS01000008_gene1510	8.04e-122	394.0	COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,46NTM@74030|Roseovarius	28211|Alphaproteobacteria	M	27 kDa outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
CMS1_k127_314896_10	1288298.rosmuc_01531	1.385e-44	167.0	2EA8J@1|root,334D2@2|Bacteria,1N89R@1224|Proteobacteria,2UFFH@28211|Alphaproteobacteria,46QY8@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
CMS1_k127_314896_0	1288298.rosmuc_01313	1.306e-257	799.0	COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,2TVXR@28211|Alphaproteobacteria,46NED@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS1_k127_314896_6	391613.RTM1035_09985	6.875e-186	584.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TR81@28211|Alphaproteobacteria,46NFV@74030|Roseovarius	28211|Alphaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_314896_1	314264.ROS217_21302	2.718e-222	692.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,46NY9@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4992 Ornithine acetylornithine aminotransferase	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_314896_4	391613.RTM1035_09995	4.938e-200	632.0	COG0477@1|root,2Z82B@2|Bacteria,1R9GD@1224|Proteobacteria,2TTIS@28211|Alphaproteobacteria,46PYU@74030|Roseovarius	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_314896_9	1288298.rosmuc_01308	2.299e-46	171.0	2E7N5@1|root,3323Z@2|Bacteria,1NB47@1224|Proteobacteria,2UH0W@28211|Alphaproteobacteria,46R0Q@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_314896_5	1354722.JQLS01000008_gene1749	1.214e-196	614.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,2TT68@28211|Alphaproteobacteria,46QG3@74030|Roseovarius	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_314896_8	314264.ROS217_21327	1.572e-66	231.0	COG1309@1|root,COG1309@2|Bacteria,1N6WG@1224|Proteobacteria,2UG93@28211|Alphaproteobacteria,46R6C@74030|Roseovarius	28211|Alphaproteobacteria	K	transcriptional regulator, TetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
CMS1_k127_314896_11	314264.ROS217_21332	2.556e-41	154.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2U08T@28211|Alphaproteobacteria,46PHT@74030|Roseovarius	28211|Alphaproteobacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291,ko:K18163	ko00906,ko01062,ko01100,ko01110,ko04714,map00906,map01062,map01100,map01110,map04714	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	SQS_PSY
CMS1_k127_315470_2	391613.RTM1035_19311	4.84e-29	117.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,46P8H@74030|Roseovarius	28211|Alphaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	ccrM	-	2.1.1.72	ko:K13581	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS1_k127_315470_1	314264.ROS217_09320	3.54e-96	320.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,46NAK@74030|Roseovarius	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_315470_3	1354722.JQLS01000008_gene3565	1.041e-23	107.0	2EMK8@1|root,33F8P@2|Bacteria,1NM74@1224|Proteobacteria,2UK15@28211|Alphaproteobacteria,46QUW@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_315470_4	1288298.rosmuc_00372	1.69e-17	87.0	2BVAU@1|root,32QQQ@2|Bacteria,1Q4SC@1224|Proteobacteria,2VB7G@28211|Alphaproteobacteria,46R61@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_315470_0	351016.RAZWK3B_00810	6.869e-113	370.0	COG3710@1|root,COG3710@2|Bacteria,1MWRQ@1224|Proteobacteria,2TUSX@28211|Alphaproteobacteria,2P1K5@2433|Roseobacter	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS1_k127_315754_4	314264.ROS217_09742	8.611e-98	320.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,46PK0@74030|Roseovarius	28211|Alphaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS1_k127_315754_5	1525715.IX54_03595	6.817e-69	240.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,2PVKX@265|Paracoccus	28211|Alphaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS1_k127_315754_0	314264.ROS217_09732	2.416e-208	651.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,46PQN@74030|Roseovarius	28211|Alphaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_315754_2	1354722.JQLS01000008_gene3502	2.57e-142	457.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,46PYG@74030|Roseovarius	28211|Alphaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_315754_1	1354722.JQLS01000008_gene3503	9.898e-144	458.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,46PM6@74030|Roseovarius	28211|Alphaproteobacteria	D	COG1192 ATPases involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_315754_6	252305.OB2597_12548	2.504e-59	212.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,2PE27@252301|Oceanicola	28211|Alphaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS1_k127_315754_3	1354722.JQLS01000008_gene3505	4.326e-134	432.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,46PNE@74030|Roseovarius	28211|Alphaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_3175062_0	314264.ROS217_21397	3.388e-290	904.0	COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,46PB6@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane metal-binding protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
CMS1_k127_3175062_2	391613.RTM1035_10110	1.298e-271	840.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,46NA2@74030|Roseovarius	28211|Alphaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_3175062_1	1354722.JQLS01000008_gene1213	6.893e-273	842.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,46NXY@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_318012_4	314264.ROS217_13546	3.263e-109	357.0	COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,2TS3P@28211|Alphaproteobacteria,46P14@74030|Roseovarius	28211|Alphaproteobacteria	H	COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent)	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
CMS1_k127_318012_11	666509.RCA23_c00680	9.15e-50	182.0	COG3576@1|root,COG3576@2|Bacteria,1N1V1@1224|Proteobacteria,2UEXF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_318012_1	246200.SPO3399	4.737e-157	502.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TUVG@28211|Alphaproteobacteria,4NAW1@97050|Ruegeria	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_318012_0	1288298.rosmuc_02373	0.0	1573.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,46NKB@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the GcvT family	dmgdh4	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS1_k127_318012_10	1354722.JQLS01000008_gene338	6.769e-64	220.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2UC7G@28211|Alphaproteobacteria,46QYW@74030|Roseovarius	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_318012_6	1288298.rosmuc_02371	4.62e-105	347.0	COG1280@1|root,COG1280@2|Bacteria,1PD53@1224|Proteobacteria,2TTWZ@28211|Alphaproteobacteria,46P41@74030|Roseovarius	28211|Alphaproteobacteria	E	threonine efflux protein	rhtB	-	-	ko:K05834	-	-	-	-	ko00000,ko02000	2.A.76.1.1	-	-	LysE
CMS1_k127_318012_5	314264.ROS217_13521	4.6e-105	343.0	COG1396@1|root,COG1396@2|Bacteria,1RJG9@1224|Proteobacteria,2U8MZ@28211|Alphaproteobacteria,46PQB@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
CMS1_k127_318012_3	1354722.JQLS01000008_gene2624	4.299e-139	447.0	COG1171@1|root,COG1171@2|Bacteria,1MW2Q@1224|Proteobacteria,2TTP9@28211|Alphaproteobacteria,46NUE@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1171 Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_318012_2	391613.RTM1035_15412	2.197e-153	487.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,46PZU@74030|Roseovarius	28211|Alphaproteobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_318012_8	1354722.JQLS01000008_gene2626	3.549e-93	312.0	2AFPW@1|root,315RN@2|Bacteria,1Q4F2@1224|Proteobacteria,2V443@28211|Alphaproteobacteria,46RKE@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_318012_7	1354722.JQLS01000008_gene2627	1.196e-101	336.0	2AFPW@1|root,315RN@2|Bacteria,1N1K1@1224|Proteobacteria,2UNI1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_318012_9	391589.RGAI101_2969	6.408e-76	259.0	COG1309@1|root,COG1309@2|Bacteria,1N0XU@1224|Proteobacteria,2U82V@28211|Alphaproteobacteria,2P3XU@2433|Roseobacter	28211|Alphaproteobacteria	K	transcriptional Regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS1_k127_318012_12	391593.RCCS2_16901	2.733e-18	85.0	COG4727@1|root,COG4727@2|Bacteria,1R6TR@1224|Proteobacteria,2U8E2@28211|Alphaproteobacteria,2P16D@2433|Roseobacter	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2145
CMS1_k127_3192687_2	1305735.JAFT01000005_gene3340	1.05e-50	181.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,2PD02@252301|Oceanicola	28211|Alphaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_3192687_0	1354722.JQLS01000008_gene1377	3.199e-168	534.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria,46PE5@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8
CMS1_k127_3192687_1	644107.SL1157_A0023	5.904e-158	505.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,4NAZW@97050|Ruegeria	28211|Alphaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_3192687_3	644107.SL1157_A0024	1.897e-09	60.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria,4NAC0@97050|Ruegeria	28211|Alphaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
CMS1_k127_3193234_4	314256.OG2516_06931	1.238e-112	368.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,2PDFG@252301|Oceanicola	28211|Alphaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_3193234_3	1354722.JQLS01000008_gene943	5.243e-125	406.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TSD9@28211|Alphaproteobacteria,46NEX@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3193234_6	1122614.JHZF01000011_gene1396	3.791e-78	269.0	COG0287@1|root,COG0287@2|Bacteria	2|Bacteria	E	prephenate dehydrogenase (NADP+) activity	tyrA	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
CMS1_k127_3193234_1	1461694.ATO9_22400	1.242e-141	454.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,2PEKQ@252301|Oceanicola	28211|Alphaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS1_k127_3193234_5	314264.ROS217_09575	1.345e-111	365.0	COG0730@1|root,COG0730@2|Bacteria,1PJR4@1224|Proteobacteria,2TU14@28211|Alphaproteobacteria,46P3U@74030|Roseovarius	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_3193234_2	1288298.rosmuc_00212	7.18e-141	452.0	COG0583@1|root,COG0583@2|Bacteria,1N178@1224|Proteobacteria,2TS42@28211|Alphaproteobacteria,46PQP@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3193234_0	391613.RTM1035_18665	4.203e-185	582.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2UR9F@28211|Alphaproteobacteria,46PKN@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_3204628_1	1288298.rosmuc_03698	3.365e-113	365.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,46QIY@74030|Roseovarius	28211|Alphaproteobacteria	T	Containing CheY-like receiver, AAA-type ATPase, and DNA-binding	dctD	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3204628_0	391595.RLO149_c022510	1.457e-260	812.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,2P1AZ@2433|Roseobacter	28211|Alphaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS1_k127_3219069_3	391613.RTM1035_14532	7.593e-210	656.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,46NNN@74030|Roseovarius	28211|Alphaproteobacteria	U	Type II IV secretion system protein, TadA subfamily	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS1_k127_3219069_2	391613.RTM1035_14527	8.652e-214	668.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,46Q50@74030|Roseovarius	28211|Alphaproteobacteria	U	AAA domain	minD	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
CMS1_k127_3219069_8	314264.ROS217_04555	4.362e-107	350.0	COG2885@1|root,COG2885@2|Bacteria,1RAB7@1224|Proteobacteria,2U68U@28211|Alphaproteobacteria,46NE8@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS1_k127_3219069_1	1288298.rosmuc_01734	8.798e-249	773.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,46NBQ@74030|Roseovarius	28211|Alphaproteobacteria	U	Bacterial type II III secretion system protein	pulD	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
CMS1_k127_3219069_5	314264.ROS217_04540	1.402e-134	434.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,46PAF@74030|Roseovarius	28211|Alphaproteobacteria	U	COG3745 Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS1_k127_3219069_9	351016.RAZWK3B_06807	1.58e-20	96.0	2EG71@1|root,339YX@2|Bacteria,1NGRD@1224|Proteobacteria,2UJGM@28211|Alphaproteobacteria,2P3SE@2433|Roseobacter	28211|Alphaproteobacteria	S	COG3847 Flp pilus assembly protein pilin Flp	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3219069_7	314264.ROS217_04530	2.885e-108	357.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TQTD@28211|Alphaproteobacteria,46PKX@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_3219069_6	1469613.JT55_14700	6.301e-120	388.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,3FCJJ@34008|Rhodovulum	28211|Alphaproteobacteria	I	Coenzyme A transferase	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS1_k127_3219069_4	83219.PM02_15535	1.22e-139	445.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,3ZW44@60136|Sulfitobacter	28211|Alphaproteobacteria	I	Coenzyme A transferase	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS1_k127_3219069_0	1354722.JQLS01000008_gene2382	0.0	1075.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,46NV2@74030|Roseovarius	28211|Alphaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS1_k127_3228360_0	391613.RTM1035_11400	0.0	1313.0	COG0025@1|root,COG0664@1|root,COG0025@2|Bacteria,COG0664@2|Bacteria,1MW5T@1224|Proteobacteria,2TSHB@28211|Alphaproteobacteria,46PDY@74030|Roseovarius	28211|Alphaproteobacteria	PT	COG0025 NhaP-type Na H and K H antiporters	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
CMS1_k127_3228360_1	1354722.JQLS01000008_gene908	1.601e-273	847.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TUH6@28211|Alphaproteobacteria,46NWV@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_3228360_2	1354722.JQLS01000008_gene909	3.384e-150	478.0	COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,2U0JA@28211|Alphaproteobacteria,46PAX@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_3228360_4	1123034.JMKP01000021_gene2379	7.389e-06	48.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3228360_3	1185766.DL1_11795	4.026e-59	207.0	COG0582@1|root,COG0582@2|Bacteria,1R3TM@1224|Proteobacteria,2TS94@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_3259391_0	391613.RTM1035_16497	4.237e-95	315.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,46PVB@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS1_k127_3259391_2	1288298.rosmuc_00729	4.499e-55	194.0	COG3502@1|root,COG3502@2|Bacteria,1MZEQ@1224|Proteobacteria,2UBR3@28211|Alphaproteobacteria,46QY5@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_22095	-	-	-	-	-	-	-	-	-	-	-	DUF952
CMS1_k127_3259391_1	1288298.rosmuc_00728	1.619e-70	242.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,46PTF@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_3260229_2	1354722.JQLS01000008_gene3292	5.434e-80	269.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,46PS2@74030|Roseovarius	28211|Alphaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	GO:0008150,GO:0042221,GO:0046677,GO:0050896	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS1_k127_3260229_1	1288298.rosmuc_00108	4.635e-293	902.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,46NDT@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS1_k127_3260229_0	314264.ROS217_10182	0.0	2852.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,46NZG@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0067 Glutamate synthase domain 1	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_3274516_1	351016.RAZWK3B_18433	3.489e-163	517.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,2P1V7@2433|Roseobacter	28211|Alphaproteobacteria	S	transport system, fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3274516_0	351016.RAZWK3B_18438	7.534e-183	574.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,2P2A6@2433|Roseobacter	28211|Alphaproteobacteria	S	transport system, periplasmic component	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_3304781_1	1354722.JQLS01000008_gene1234	5.702e-167	526.0	COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria,2TQNB@28211|Alphaproteobacteria,46QFR@74030|Roseovarius	28211|Alphaproteobacteria	CH	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	fpr	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
CMS1_k127_3304781_3	391613.RTM1035_09389	2.515e-62	219.0	COG3749@1|root,COG3749@2|Bacteria,1QV31@1224|Proteobacteria,2U9VA@28211|Alphaproteobacteria,46QT6@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
CMS1_k127_3304781_2	1461694.ATO9_12585	2.441e-109	366.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria,2PCSH@252301|Oceanicola	28211|Alphaproteobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF934,PAPS_reduct
CMS1_k127_3304781_0	1288298.rosmuc_01365	0.0	1023.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,46NQE@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0155 Sulfite reductase, beta subunit (hemoprotein)	cysI	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS1_k127_3304781_4	1354722.JQLS01000008_gene1238	8.132e-48	175.0	2CAHY@1|root,32RRF@2|Bacteria,1MZVR@1224|Proteobacteria,2UBQ6@28211|Alphaproteobacteria,46R32@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2849
CMS1_k127_3304781_5	1354722.JQLS01000008_gene1239	7.643e-16	78.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,46Q5S@74030|Roseovarius	28211|Alphaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS1_k127_3316963_0	1288298.rosmuc_02878	3.058e-233	729.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,46NJG@74030|Roseovarius	28211|Alphaproteobacteria	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	msbA2	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3319772_0	391613.RTM1035_08849	0.0	1029.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,46Q1Q@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	uup	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
CMS1_k127_3319772_2	1354722.JQLS01000008_gene1577	3.254e-128	413.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,46NVC@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_3319772_1	391613.RTM1035_08839	1.677e-158	507.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2TUUX@28211|Alphaproteobacteria,46PN1@74030|Roseovarius	28211|Alphaproteobacteria	S	Pfam:AmoA	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
CMS1_k127_3319772_3	314264.ROS217_20957	5.288e-93	307.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,46NTE@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	iorB	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS1_k127_3326842_1	1305735.JAFT01000005_gene1684	1.198e-233	729.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2PCZC@252301|Oceanicola	28211|Alphaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_3326842_5	766499.C357_08126	5.579e-40	149.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS1_k127_3326842_2	391613.RTM1035_19391	2.007e-173	545.0	2CB2F@1|root,2Z7N3@2|Bacteria,1P5KB@1224|Proteobacteria,2TR8T@28211|Alphaproteobacteria,46PK5@74030|Roseovarius	28211|Alphaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS1_k127_3326842_0	1288298.rosmuc_00385	6.641e-316	970.0	2CEUT@1|root,2Z86D@2|Bacteria,1N5P4@1224|Proteobacteria,2TSAQ@28211|Alphaproteobacteria,46Q1V@74030|Roseovarius	28211|Alphaproteobacteria	S	Core-2/I-Branching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Branch
CMS1_k127_3326842_4	314264.ROS217_10327	1.412e-64	223.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,46QXB@74030|Roseovarius	28211|Alphaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	pkcI	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS1_k127_3326842_3	1288298.rosmuc_00387	1.845e-135	435.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,2TSNZ@28211|Alphaproteobacteria,46QJ4@74030|Roseovarius	28211|Alphaproteobacteria	P	Ion transport protein	ccaA	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
CMS1_k127_3359014_1	266809.PM03_16160	1.817e-270	833.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TRWC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	glxD	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
CMS1_k127_3359014_0	571166.KI421509_gene4018	1.573e-271	841.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TTWE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glutamine synthetase	glnT	-	6.3.1.2,6.3.4.12	ko:K01915,ko:K01949	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
CMS1_k127_3359014_6	571166.KI421509_gene4008	1.386e-59	209.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2UAFE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protozoan cyanobacterial globin family protein	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS1_k127_3359014_4	571166.KI421509_gene4007	4.844e-67	243.0	COG0697@1|root,COG0697@2|Bacteria,1RCE1@1224|Proteobacteria,2U6XB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_3359014_7	89187.ISM_03815	1.845e-50	182.0	COG3450@1|root,COG3450@2|Bacteria,1RKUC@1224|Proteobacteria,2UA08@28211|Alphaproteobacteria,46QZ3@74030|Roseovarius	28211|Alphaproteobacteria	S	enzyme of the cupin superfamily	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
CMS1_k127_3359014_3	391595.RLO149_c005670	1.112e-69	241.0	COG0662@1|root,COG0662@2|Bacteria,1QZG8@1224|Proteobacteria,2TY8W@28211|Alphaproteobacteria,2P3XR@2433|Roseobacter	28211|Alphaproteobacteria	G	Dimethlysulfonioproprionate lyase	-	-	-	-	-	-	-	-	-	-	-	-	DMSP_lyase
CMS1_k127_3359014_2	375451.RD1_3867	8.633e-147	470.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2TV0M@28211|Alphaproteobacteria,2P586@2433|Roseobacter	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3359014_5	375451.RD1_3866	6.635e-61	212.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TUMK@28211|Alphaproteobacteria,2P11U@2433|Roseobacter	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_336149_6	1123360.thalar_02795	1.218e-79	268.0	COG3009@1|root,COG3009@2|Bacteria,1RH03@1224|Proteobacteria,2U9EI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
CMS1_k127_336149_4	89187.ISM_10965	8.634e-103	343.0	COG0583@1|root,COG0583@2|Bacteria,1MX53@1224|Proteobacteria,2TTGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	pcaQ	-	-	ko:K02623	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_336149_0	314232.SKA53_03704	8.076e-218	684.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2TRB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	4-hydroxybenzoate	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
CMS1_k127_336149_7	411684.HPDFL43_10721	2.742e-58	205.0	COG0599@1|root,COG0599@2|Bacteria,1RDSG@1224|Proteobacteria,2U72V@28211|Alphaproteobacteria,43K4T@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	4-carboxymuconolactone decarboxylase	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
CMS1_k127_336149_2	1354722.JQLS01000008_gene2284	2.887e-148	470.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2TU2C@28211|Alphaproteobacteria,46QGR@74030|Roseovarius	28211|Alphaproteobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
CMS1_k127_336149_3	1354722.JQLS01000008_gene2285	7.611e-106	345.0	COG3485@1|root,COG3485@2|Bacteria,1MV3B@1224|Proteobacteria,2TTZJ@28211|Alphaproteobacteria,46QNZ@74030|Roseovarius	28211|Alphaproteobacteria	Q	Dioxygenase	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
CMS1_k127_336149_1	376733.IT41_03620	2.252e-150	478.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TRG7@28211|Alphaproteobacteria,2PVX5@265|Paracoccus	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
CMS1_k127_336149_5	314264.ROS217_13566	2.69e-89	302.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TVZ2@28211|Alphaproteobacteria,46RRE@74030|Roseovarius	28211|Alphaproteobacteria	I	Ndr family	pcaD	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,CMD
CMS1_k127_336149_8	1185766.DL1_10690	2.486e-21	101.0	COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,2TRCE@28211|Alphaproteobacteria,2XPDA@285107|Thioclava	28211|Alphaproteobacteria	F	Lyase	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
CMS1_k127_3372775_3	883080.HMPREF9697_01694	2.777e-13	70.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2TVQ7@28211|Alphaproteobacteria,3JTKU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
CMS1_k127_3372775_2	391624.OIHEL45_02680	7.578e-102	334.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Aldolase	eda	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
CMS1_k127_3372775_0	391624.OIHEL45_02685	0.0	1010.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,2TQNS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	Belongs to the IlvD Edd family	edd	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_3372775_1	391589.RGAI101_2365	2.773e-147	469.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2TRR3@28211|Alphaproteobacteria,2P2KR@2433|Roseobacter	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015416,GO:0015604,GO:0015605,GO:0015698,GO:0015716,GO:0015748,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:0099133	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
CMS1_k127_3372775_4	391616.OA238_c39360	2.249e-10	63.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,2TQMQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Phosphonate ABC transporter	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS1_k127_3373028_1	1110502.TMO_0781	4.227e-07	59.0	COG3133@1|root,COG3133@2|Bacteria,1N6VZ@1224|Proteobacteria,2UJG5@28211|Alphaproteobacteria,2JWX9@204441|Rhodospirillales	204441|Rhodospirillales	M	Outer membrane lipoprotein	-	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_3373028_0	1122135.KB893157_gene452	2.041e-60	220.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	nlpD2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_3390137_5	1288298.rosmuc_03436	1.832e-83	284.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,46QHQ@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0007 Uroporphyrinogen-III methylase	cobA	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS1_k127_3390137_1	1354722.JQLS01000008_gene1819	6.941e-185	582.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,2TRFH@28211|Alphaproteobacteria,46PIR@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
CMS1_k127_3390137_3	1354722.JQLS01000008_gene1818	2.929e-107	353.0	COG2099@1|root,COG2099@2|Bacteria,1MW48@1224|Proteobacteria,2TWW4@28211|Alphaproteobacteria,46QE5@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2099 Precorrin-6x reductase	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
CMS1_k127_3390137_4	391613.RTM1035_11700	3.138e-98	324.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,46QFE@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS1_k127_3390137_2	314264.ROS217_21867	2.753e-129	416.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2TTWP@28211|Alphaproteobacteria,46P29@74030|Roseovarius	28211|Alphaproteobacteria	S	Phospholipase carboxylesterase family protein	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS1_k127_3390137_0	391613.RTM1035_11690	1.166e-207	658.0	COG1266@1|root,COG1266@2|Bacteria,1QNYJ@1224|Proteobacteria,2TVGU@28211|Alphaproteobacteria,46P4P@74030|Roseovarius	28211|Alphaproteobacteria	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi,Exosortase_EpsH
CMS1_k127_3390137_7	1288298.rosmuc_03294	1.795e-13	71.0	2ESTE@1|root,300V4@2|Bacteria,1PRJ7@1224|Proteobacteria,2V3UC@28211|Alphaproteobacteria,46S2B@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3390137_6	351016.RAZWK3B_18023	4.29e-77	261.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2P1D8@2433|Roseobacter	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	ttgE	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
CMS1_k127_3395394_0	1354722.JQLS01000008_gene1575	1.509e-262	815.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,46NTE@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	iorB	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS1_k127_3396961_0	314264.ROS217_11186	5.154e-239	741.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,46PHC@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the thiolase family	phbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_3421415_5	1123247.AUIJ01000001_gene1510	2.157e-07	54.0	2CA50@1|root,32YIT@2|Bacteria,1N822@1224|Proteobacteria,2UFR0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2842
CMS1_k127_3421415_0	439496.RBY4I_1140	1.396e-269	831.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_3421415_3	83219.PM02_14390	6.253e-55	194.0	2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,2U9H2@28211|Alphaproteobacteria,3ZXQ8@60136|Sulfitobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3421415_1	89187.ISM_03950	4.973e-151	482.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2TRIC@28211|Alphaproteobacteria,46PHA@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane transporter protein	MA20_19835	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_3421415_4	314264.ROS217_20582	2.735e-53	189.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2UCIP@28211|Alphaproteobacteria,46QXQ@74030|Roseovarius	28211|Alphaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS1_k127_3421415_2	375451.RD1_1906	2.114e-84	281.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,2P1WK@2433|Roseobacter	28211|Alphaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS1_k127_343304_5	501479.ACNW01000120_gene3405	2.561e-12	70.0	2EPUF@1|root,33HEX@2|Bacteria,1NJFN@1224|Proteobacteria,2UKVF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_343304_2	1049564.TevJSym_af00130	4.151e-119	391.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1J5VE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	DnaJ-class molecular chaperone	cbpA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS1_k127_343304_4	1492922.GY26_01705	1.057e-16	83.0	COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,1J77U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	MerR HTH family regulatory protein	cbpM	-	-	ko:K18997	-	-	-	-	ko00000,ko03036	-	-	-	MerR_2
CMS1_k127_343304_7	765912.Thimo_2567	3.68e-10	69.0	COG3247@1|root,COG3247@2|Bacteria,1RFIH@1224|Proteobacteria,1S6XJ@1236|Gammaproteobacteria,1WYQ5@135613|Chromatiales	135613|Chromatiales	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
CMS1_k127_343304_0	89187.ISM_09301	1.244e-173	550.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2TSRR@28211|Alphaproteobacteria,46Q7I@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_343304_1	351016.RAZWK3B_18103	2.321e-135	435.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2TRYX@28211|Alphaproteobacteria,2P3AA@2433|Roseobacter	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_343304_3	999547.KI421500_gene1282	8.46e-83	282.0	28J78@1|root,2Z92P@2|Bacteria,1PEDU@1224|Proteobacteria,2TT0K@28211|Alphaproteobacteria,27ZT2@191028|Leisingera	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_343304_6	1354722.JQLS01000008_gene2044	8.108e-11	62.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2UJKX@28211|Alphaproteobacteria,46R4A@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
CMS1_k127_3477788_0	89187.ISM_16790	6.849e-285	876.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,46P7V@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS1_k127_3477788_1	1354722.JQLS01000008_gene1285	2.319e-22	97.0	2F5MI@1|root,33Y6N@2|Bacteria,1NWWQ@1224|Proteobacteria,2USFT@28211|Alphaproteobacteria,46QEI@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3532724_3	744980.TRICHSKD4_5106	5.913e-47	169.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TQSZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the arginase family	speB-4	-	3.5.3.11,3.5.3.17	ko:K01480,ko:K18459	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS1_k127_3532724_1	391626.OAN307_c18250	1.826e-94	318.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,2TV6T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_3532724_0	391626.OAN307_c18260	1.159e-115	377.0	COG1028@1|root,COG1028@2|Bacteria,1R48C@1224|Proteobacteria,2U3SV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3532724_2	391626.OAN307_c18270	2.381e-89	296.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system	-	-	3.6.3.36	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
CMS1_k127_3557949_8	1415756.JQMY01000001_gene2188	2.672e-08	55.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,2PCAN@252301|Oceanicola	28211|Alphaproteobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CMS1_k127_3557949_7	314264.ROS217_17292	8.592e-86	285.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,46QQZ@74030|Roseovarius	28211|Alphaproteobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_3557949_0	1354722.JQLS01000008_gene883	0.0	1418.0	COG3164@1|root,COG3164@2|Bacteria,1MVDY@1224|Proteobacteria,2TSGG@28211|Alphaproteobacteria,46NQQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function	MA20_30770	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
CMS1_k127_3557949_4	1354722.JQLS01000008_gene884	2.396e-187	592.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria,46P11@74030|Roseovarius	28211|Alphaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS1_k127_3557949_3	314264.ROS217_17307	2.607e-230	718.0	COG0477@1|root,COG0477@2|Bacteria,1QTUM@1224|Proteobacteria,2TVX9@28211|Alphaproteobacteria,46P1D@74030|Roseovarius	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_3557949_5	314264.ROS217_17312	5.831e-99	325.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2U7AN@28211|Alphaproteobacteria,46QA6@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
CMS1_k127_3557949_2	314264.ROS217_17317	4.796e-283	872.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,46PTB@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_3557949_6	351016.RAZWK3B_14084	1.943e-94	312.0	COG2227@1|root,COG2227@2|Bacteria,1RA12@1224|Proteobacteria,2U6CZ@28211|Alphaproteobacteria,2P4SI@2433|Roseobacter	28211|Alphaproteobacteria	C	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_3557949_1	1354722.JQLS01000008_gene1224	1.894e-300	923.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,46PH0@74030|Roseovarius	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_3558709_4	351016.RAZWK3B_13529	0.000255	47.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2V98C@28211|Alphaproteobacteria,2P1KZ@2433|Roseobacter	28211|Alphaproteobacteria	O	Peptidase, M48 family	-	-	-	ko:K07387	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M48
CMS1_k127_3558709_1	391613.RTM1035_10300	3.045e-174	550.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2TSJP@28211|Alphaproteobacteria,46PZY@74030|Roseovarius	28211|Alphaproteobacteria	S	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS1_k127_3558709_0	314264.ROS217_18447	1.838e-278	861.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,46NIZ@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS1_k127_3558709_2	1354722.JQLS01000008_gene1779	4.431e-109	359.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2U77K@28211|Alphaproteobacteria,46NYK@74030|Roseovarius	28211|Alphaproteobacteria	G	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CMS1_k127_3558709_3	1288298.rosmuc_03528	1.318e-39	151.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,46QI3@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the GPI family	pgi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS1_k127_356592_0	1354722.JQLS01000008_gene635	7.904e-179	561.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,46PB9@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0439 Biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS1_k127_356592_1	1354722.JQLS01000008_gene636	1.11e-75	258.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,46P4R@74030|Roseovarius	28211|Alphaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS1_k127_356592_2	1288298.rosmuc_01010	1.429e-45	165.0	COG2197@1|root,COG2197@2|Bacteria,1RAAY@1224|Proteobacteria,2U69Z@28211|Alphaproteobacteria,46PR9@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS,PAS_3,PAS_9
CMS1_k127_3569074_12	314264.ROS217_10217	7.55e-127	414.0	COG2931@1|root,COG2931@2|Bacteria,1RIMS@1224|Proteobacteria,2UBKN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_3569074_15	1288298.rosmuc_00118	5.927e-80	280.0	COG1522@1|root,COG1522@2|Bacteria,1RI7R@1224|Proteobacteria,2U9CC@28211|Alphaproteobacteria,46QB0@74030|Roseovarius	28211|Alphaproteobacteria	K	transcriptional regulator, AsnC family	aldR	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_3569074_3	1288298.rosmuc_00119	1.766e-219	684.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,46QJS@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_3569074_5	1354722.JQLS01000008_gene3277	1.617e-189	595.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TU4H@28211|Alphaproteobacteria,46NVB@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	mcl1	GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_3569074_4	1354722.JQLS01000008_gene3276	6.9e-196	614.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria,46QBT@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
CMS1_k127_3569074_6	314264.ROS217_10262	3.586e-185	581.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria,46Q0D@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	ycjG	GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3569074_7	1288298.rosmuc_00132	3.39e-167	528.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2TR7R@28211|Alphaproteobacteria,46NFZ@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_3569074_14	391613.RTM1035_18095	5.811e-94	310.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,46QM6@74030|Roseovarius	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	MA20_22790	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS1_k127_3569074_9	1354722.JQLS01000008_gene3272	2.923e-165	522.0	COG0115@1|root,COG0115@2|Bacteria,1MX5D@1224|Proteobacteria,2TRVR@28211|Alphaproteobacteria,46PXW@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_3569074_0	89187.ISM_05950	7.355e-268	826.0	COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,2TREY@28211|Alphaproteobacteria,46PTV@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
CMS1_k127_3569074_8	439496.RBY4I_208	1.272e-165	522.0	COG3257@1|root,COG3257@2|Bacteria,1MW60@1224|Proteobacteria,2TS34@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein possibly involved in glyoxylate utilization	allE	-	3.5.3.26	ko:K14977	ko00230,ko01120,map00230,map01120	-	R05554	RC01419	ko00000,ko00001,ko01000	-	-	-	Cupin_2
CMS1_k127_3569074_16	999547.KI421502_gene3851	6.861e-79	267.0	COG3194@1|root,COG3194@2|Bacteria,1RH5G@1224|Proteobacteria,2U8A4@28211|Alphaproteobacteria,2826V@191028|Leisingera	28211|Alphaproteobacteria	F	Ureidoglycolate lyase	allA	-	4.3.2.3	ko:K01483	ko00230,ko01100,map00230,map01100	-	R00776	RC00153,RC00379	ko00000,ko00001,ko01000	-	-	-	Ureidogly_lyase
CMS1_k127_3569074_1	1469613.JT55_17835	3.527e-243	758.0	COG0726@1|root,COG3195@1|root,COG0726@2|Bacteria,COG3195@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3FD9S@34008|Rhodovulum	28211|Alphaproteobacteria	G	OHCU decarboxylase	pucL	-	1.7.3.3,3.5.1.41	ko:K00365,ko:K01452	ko00230,ko00232,ko00520,ko01100,ko01120,map00230,map00232,map00520,map01100,map01120	M00546	R02106,R02333,R07981	RC00166,RC00300,RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox,Polysacc_deac_1
CMS1_k127_3569074_17	391593.RCCS2_03127	1.386e-58	206.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,2U9IT@28211|Alphaproteobacteria,2P3E5@2433|Roseobacter	28211|Alphaproteobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
CMS1_k127_3569074_10	1002340.AFCF01000005_gene2970	5.276e-159	505.0	COG0583@1|root,COG0583@2|Bacteria,1MVJ7@1224|Proteobacteria,2TT9Z@28211|Alphaproteobacteria,34ECE@302485|Phaeobacter	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3569074_2	1002340.AFCF01000005_gene2971	2.132e-231	729.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2TSXN@28211|Alphaproteobacteria,34ERE@302485|Phaeobacter	28211|Alphaproteobacteria	P	Urate oxidase N-terminal	MA20_17625	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
CMS1_k127_3569074_11	1288298.rosmuc_00374	5.502e-154	489.0	COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,2TRGQ@28211|Alphaproteobacteria,46Q7T@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional Regulator, LysR family protein	cuyR	-	-	ko:K21645	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3569074_13	1354722.JQLS01000008_gene3561	1.048e-99	327.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,46NG8@74030|Roseovarius	28211|Alphaproteobacteria	E	COG2515 1-aminocyclopropane-1-carboxylate deaminase	cuyA	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0034011,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	4.4.1.15,4.4.1.25	ko:K05396,ko:K17950	ko00270,map00270	-	R01874,R07634	RC00382,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
CMS1_k127_3577535_0	314264.ROS217_17767	4.217e-308	946.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,46PQR@74030|Roseovarius	28211|Alphaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_3577535_1	351016.RAZWK3B_14354	3.842e-206	649.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2P19H@2433|Roseobacter	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS1_k127_3577535_3	1354722.JQLS01000008_gene888	1.91e-133	430.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,46Q7B@74030|Roseovarius	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
CMS1_k127_3577535_4	351016.RAZWK3B_16480	1.092e-22	98.0	2EK7J@1|root,33DXX@2|Bacteria,1NIMR@1224|Proteobacteria,2UKIE@28211|Alphaproteobacteria,2P3XN@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3577535_2	314264.ROS217_17332	3.182e-154	488.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,46QHX@74030|Roseovarius	28211|Alphaproteobacteria	P	And related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_3620972_2	1354722.JQLS01000008_gene772	1.96e-132	425.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,46Q7Z@74030|Roseovarius	28211|Alphaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_3620972_0	1354722.JQLS01000008_gene771	0.0	1013.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,46PAW@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0768 Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_3620972_5	1354722.JQLS01000008_gene770	7.007e-53	193.0	COG5462@1|root,COG5462@2|Bacteria,1N1DA@1224|Proteobacteria,2UBXT@28211|Alphaproteobacteria,46QXI@74030|Roseovarius	28211|Alphaproteobacteria	S	secreted (Periplasmic) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3620972_1	1354722.JQLS01000008_gene769	7.804e-167	530.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,46PY6@74030|Roseovarius	28211|Alphaproteobacteria	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS1_k127_3620972_3	314264.ROS217_22792	1.076e-89	297.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,46NRE@74030|Roseovarius	28211|Alphaproteobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS1_k127_3620972_7	644076.SCH4B_1684	1.956e-08	58.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,4NBZJ@97050|Ruegeria	28211|Alphaproteobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS1_k127_3620972_4	391613.RTM1035_03440	1.191e-80	272.0	COG0454@1|root,COG0456@2|Bacteria,1QUWI@1224|Proteobacteria,2TXQV@28211|Alphaproteobacteria,46PX7@74030|Roseovarius	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_3620972_6	1305735.JAFT01000005_gene3145	2.149e-28	114.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2TRW7@28211|Alphaproteobacteria,2PCF9@252301|Oceanicola	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	acuI	-	1.1.1.1	ko:K00001,ko:K19745	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R00919,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00095,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3624764_1	1288298.rosmuc_01271	9.941e-134	428.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TRA8@28211|Alphaproteobacteria,46PVP@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	MA20_09395	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_3624764_0	1354722.JQLS01000008_gene1055	6.799e-269	829.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,46P7X@74030|Roseovarius	28211|Alphaproteobacteria	S	related to penicillin acylase	quiP	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_3631041_5	292414.TM1040_3780	5.821e-127	412.0	COG3291@1|root,COG3291@2|Bacteria,1N0V6@1224|Proteobacteria,2U316@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394
CMS1_k127_3631041_0	1288298.rosmuc_00759	8.499e-320	984.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,46QHR@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	MA20_29420	-	6.2.1.44,6.2.1.48	ko:K00666,ko:K02182,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3631041_4	1288298.rosmuc_00758	6.508e-140	449.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2TTMB@28211|Alphaproteobacteria,46QD9@74030|Roseovarius	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	Echdc	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_3631041_6	999549.KI421513_gene2362	1.986e-84	282.0	COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2U99X@28211|Alphaproteobacteria,2822Q@191028|Leisingera	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_3631041_3	391589.RGAI101_184	7.337e-225	703.0	COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,2P26I@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0404 Glycine cleavage system T protein (aminomethyltransferase)	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C,SnoaL_2
CMS1_k127_3631041_8	391613.RTM1035_16627	8.076e-77	268.0	COG1522@1|root,COG1522@2|Bacteria,1RB14@1224|Proteobacteria,2U1EC@28211|Alphaproteobacteria,46NWZ@74030|Roseovarius	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K15782	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_3631041_1	1288298.rosmuc_02599	1.391e-282	873.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,46RI5@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3631041_7	1288298.rosmuc_02600	3.394e-83	279.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U75U@28211|Alphaproteobacteria,46RUR@74030|Roseovarius	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_3631041_2	1288298.rosmuc_02601	8.83e-231	716.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,46RKG@74030|Roseovarius	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
CMS1_k127_3631041_9	1121479.AUBS01000002_gene3999	1.575e-35	134.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2TSJR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS1_k127_364232_3	412597.AEPN01000033_gene588	6.371e-12	69.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2TS5Q@28211|Alphaproteobacteria,2PUU0@265|Paracoccus	28211|Alphaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_364232_1	467661.RKLH11_1342	2.202e-132	435.0	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,2TQM3@28211|Alphaproteobacteria,3ZG0E@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	M	COG3562 Capsule polysaccharide export protein	kpsS	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS1_k127_364232_2	1461693.ATO10_11327	6.185e-91	307.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	riboflavin synthase alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS1_k127_364232_0	314271.RB2654_05510	3.846e-144	460.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS1_k127_3651861_0	1469613.JT55_14690	1.047e-191	601.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,3FCQB@34008|Rhodovulum	28211|Alphaproteobacteria	G	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS1_k127_3651861_1	1317124.DW2_06663	1.706e-127	418.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2XKR6@285107|Thioclava	28211|Alphaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_3651861_2	1294273.roselon_00065	2.083e-54	192.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Modulator of DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_3658415_4	1354722.JQLS01000008_gene1385	3.595e-148	471.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,46Q0W@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_3658415_2	1354722.JQLS01000008_gene1384	3.282e-156	496.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TSD9@28211|Alphaproteobacteria,46NEX@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3658415_5	1354722.JQLS01000008_gene1383	2.586e-136	436.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,46QAN@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3658415_6	1354722.JQLS01000008_gene1382	1.654e-121	393.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,46PR3@74030|Roseovarius	28211|Alphaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS1_k127_3658415_3	1354722.JQLS01000008_gene1381	2.303e-148	472.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,46NEI@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS1_k127_3658415_0	1305735.JAFT01000005_gene1246	8.695e-184	584.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2PCSX@252301|Oceanicola	28211|Alphaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
CMS1_k127_3658415_1	644107.SL1157_A0024	1.998e-181	574.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria,4NAC0@97050|Ruegeria	28211|Alphaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
CMS1_k127_3661207_2	1354722.JQLS01000008_gene2583	1.011e-111	367.0	COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria,2V6EM@28211|Alphaproteobacteria,46PY4@74030|Roseovarius	28211|Alphaproteobacteria	U	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3661207_0	1288298.rosmuc_03817	1.431e-132	429.0	2DBIF@1|root,2Z9FG@2|Bacteria,1QYR5@1224|Proteobacteria,2TTVX@28211|Alphaproteobacteria,46QBH@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3661207_1	314264.ROS217_06464	2.88e-130	419.0	COG0697@1|root,COG0697@2|Bacteria,1PS60@1224|Proteobacteria,2V4D9@28211|Alphaproteobacteria,46QJI@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_3669868_5	391613.RTM1035_20526	3.466e-18	83.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,46P0K@74030|Roseovarius	28211|Alphaproteobacteria	IQ	related to short-chain alcohol dehydrogenases	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_3669868_0	1354722.JQLS01000008_gene1299	8.812e-230	721.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2TT46@28211|Alphaproteobacteria,46S2J@74030|Roseovarius	28211|Alphaproteobacteria	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
CMS1_k127_3669868_3	314264.ROS217_06019	1.893e-77	267.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,46RPK@74030|Roseovarius	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_3669868_1	1288298.rosmuc_00066	2.478e-180	571.0	COG1804@1|root,COG1804@2|Bacteria,1MU4A@1224|Proteobacteria,2TRSB@28211|Alphaproteobacteria,46P08@74030|Roseovarius	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_3669868_6	1038858.AXBA01000037_gene4811	0.0002429	45.0	COG4314@1|root,COG4314@2|Bacteria,1RE78@1224|Proteobacteria,2U7BU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	lipoprotein involved in nitrous oxide reduction	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS1_k127_3669868_2	1354722.JQLS01000008_gene1165	4.389e-95	319.0	COG1477@1|root,COG1477@2|Bacteria,1RAXI@1224|Proteobacteria,2VEYM@28211|Alphaproteobacteria,46QBK@74030|Roseovarius	28211|Alphaproteobacteria	M	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS1_k127_3669868_4	1461694.ATO9_14320	4.021e-34	135.0	COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,2PEMV@252301|Oceanicola	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_3680442_15	314264.ROS217_04405	1.557e-79	267.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,46NCC@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	mpp	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_3680442_9	314264.ROS217_04400	1.558e-114	372.0	COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,2TUIK@28211|Alphaproteobacteria,46N9R@74030|Roseovarius	28211|Alphaproteobacteria	J	Including N-acetylases of ribosomal proteins	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS1_k127_3680442_6	1354722.JQLS01000008_gene2370	2.139e-136	438.0	COG2220@1|root,COG2220@2|Bacteria,1NVME@1224|Proteobacteria,2U180@28211|Alphaproteobacteria,46PCI@74030|Roseovarius	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS1_k127_3680442_1	1354722.JQLS01000008_gene514	8.406e-254	788.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,46PAA@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_3680442_2	1288298.rosmuc_01912	1.517e-165	522.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,46PFA@74030|Roseovarius	28211|Alphaproteobacteria	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_3680442_10	1354722.JQLS01000008_gene516	4.796e-113	370.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria,46NZW@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1489 DNA-binding protein, stimulates sugar fermentation	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
CMS1_k127_3680442_7	1288298.rosmuc_01914	1.673e-129	417.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,46PZI@74030|Roseovarius	28211|Alphaproteobacteria	S	Related to molybdopterin-biosynthesis enzyme MoeA	cinA1	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS1_k127_3680442_14	1305735.JAFT01000005_gene1753	9.236e-90	304.0	COG0454@1|root,COG0456@2|Bacteria,1RCBE@1224|Proteobacteria,2U1JB@28211|Alphaproteobacteria,2PE8Q@252301|Oceanicola	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	yobR	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_3680442_12	1288298.rosmuc_01916	8.937e-96	322.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,46ND8@74030|Roseovarius	28211|Alphaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_3680442_11	1354722.JQLS01000008_gene520	8.119e-99	332.0	COG2885@1|root,COG2885@2|Bacteria,1R4CA@1224|Proteobacteria,2TQWJ@28211|Alphaproteobacteria,46NUX@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF4892,OmpA
CMS1_k127_3680442_17	118163.Ple7327_0395	5.974e-55	200.0	2C6BU@1|root,32S87@2|Bacteria,1G8M3@1117|Cyanobacteria,3VMS5@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3680442_16	1415756.JQMY01000001_gene1388	3.125e-57	202.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VEUJ@28211|Alphaproteobacteria,2PEEH@252301|Oceanicola	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS1_k127_3680442_4	391613.RTM1035_12613	6.628e-139	442.0	COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,2TS1K@28211|Alphaproteobacteria,46PXK@74030|Roseovarius	28211|Alphaproteobacteria	I	Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP	pcs	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_3680442_13	1354722.JQLS01000008_gene2079	3.341e-95	314.0	2BM2I@1|root,32FJK@2|Bacteria,1RH87@1224|Proteobacteria,2UADD@28211|Alphaproteobacteria,46NIQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
CMS1_k127_3680442_3	314264.ROS217_15905	4.167e-162	516.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,46P8Z@74030|Roseovarius	28211|Alphaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_3680442_5	1288298.rosmuc_02642	9.109e-139	444.0	COG3159@1|root,COG3159@2|Bacteria,1NEKF@1224|Proteobacteria,2TV4V@28211|Alphaproteobacteria,46PHE@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	xerC	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
CMS1_k127_3680442_8	391613.RTM1035_06678	3e-123	398.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,46NYR@74030|Roseovarius	28211|Alphaproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS1_k127_3680442_0	391613.RTM1035_06683	4.84e-322	1004.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,46NP0@74030|Roseovarius	28211|Alphaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
CMS1_k127_3684612_1	391613.RTM1035_19171	2.253e-157	498.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,46QKT@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3684612_2	1288298.rosmuc_00337	5.469e-131	421.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TSPM@28211|Alphaproteobacteria,46QH2@74030|Roseovarius	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_43195	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_3684612_0	391613.RTM1035_19161	2.94e-184	581.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,46PU9@74030|Roseovarius	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_3690463_1	1288298.rosmuc_02975	8.65e-322	997.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2V6JN@28211|Alphaproteobacteria,46QKC@74030|Roseovarius	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_3690463_10	1288298.rosmuc_02976	3.146e-48	175.0	2EI7I@1|root,33BYW@2|Bacteria,1NPJH@1224|Proteobacteria,2UJGF@28211|Alphaproteobacteria,46QW0@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3690463_5	1354722.JQLS01000008_gene1922	1.09e-131	426.0	COG3509@1|root,COG3509@2|Bacteria,1R9H9@1224|Proteobacteria,2U31M@28211|Alphaproteobacteria,46NT6@74030|Roseovarius	28211|Alphaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
CMS1_k127_3690463_4	1288298.rosmuc_03113	1.345e-156	499.0	COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TTBX@28211|Alphaproteobacteria,46Q1F@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_3690463_2	1354722.JQLS01000008_gene618	4.663e-258	801.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,46NS1@74030|Roseovarius	28211|Alphaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_3690463_6	1305735.JAFT01000005_gene704	2.067e-107	363.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,2TRWI@28211|Alphaproteobacteria,2PDRY@252301|Oceanicola	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
CMS1_k127_3690463_7	391613.RTM1035_05838	2.469e-89	297.0	COG3703@1|root,COG3703@2|Bacteria,1RDNV@1224|Proteobacteria,2U7V4@28211|Alphaproteobacteria,46PRH@74030|Roseovarius	28211|Alphaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	-	-	-	-	-	-	-	-	-	ChaC,GGACT
CMS1_k127_3690463_8	1354722.JQLS01000008_gene621	1.894e-76	259.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2UBZM@28211|Alphaproteobacteria,46QQS@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
CMS1_k127_3690463_3	391613.RTM1035_05848	1.284e-203	637.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,46PE1@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0404 Glycine cleavage system T protein (aminomethyltransferase)	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_3690463_9	1288298.rosmuc_03122	4.638e-57	205.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,46QV3@74030|Roseovarius	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS1_k127_3690463_0	1288298.rosmuc_03123	0.0	1797.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,46QJB@74030|Roseovarius	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
CMS1_k127_3690463_11	1354722.JQLS01000008_gene625	9.538e-48	172.0	COG2267@1|root,COG2771@1|root,COG2267@2|Bacteria,COG2771@2|Bacteria,1QV2F@1224|Proteobacteria,2U8KM@28211|Alphaproteobacteria,46S40@74030|Roseovarius	28211|Alphaproteobacteria	IK	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,GerE,Hydrolase_4
CMS1_k127_3707686_1	1354722.JQLS01000008_gene3076	1.677e-135	432.0	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2TS3C@28211|Alphaproteobacteria,46NAA@74030|Roseovarius	28211|Alphaproteobacteria	P	ABC-type spermidine putrescine transport system, permease component	potC	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
CMS1_k127_3707686_0	1479237.JMLY01000001_gene3312	2.042e-218	684.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,1S1CC@1236|Gammaproteobacteria,46ACZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
CMS1_k127_3714264_4	666685.R2APBS1_0568	4.012e-06	53.0	COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1T8NP@1236|Gammaproteobacteria,1X8SZ@135614|Xanthomonadales	135614|Xanthomonadales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS1_k127_3714264_3	1123372.AUIT01000010_gene396	1.344e-24	110.0	COG0071@1|root,COG0071@2|Bacteria,2GHTW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_3714264_2	391589.RGAI101_3988	4.294e-58	205.0	COG5502@1|root,COG5502@2|Bacteria,1NB8V@1224|Proteobacteria,2U9GZ@28211|Alphaproteobacteria,2P4YA@2433|Roseobacter	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
CMS1_k127_3714264_1	391589.RGAI101_3810	3.458e-78	268.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U36S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator, Crp Fnr family	fixK	-	-	ko:K01420,ko:K15861	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_3714264_0	1342301.JASD01000008_gene1164	1.52e-86	292.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,3ZXUY@60136|Sulfitobacter	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	ompR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3775733_4	1288298.rosmuc_00243	2.836e-143	459.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TT3Y@28211|Alphaproteobacteria,46Q5I@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	ordL	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_3775733_3	314264.ROS217_09425	2.742e-150	479.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,46PJ6@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1177 ABC-type spermidine putrescine transport system, permease component II	potI	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K11074	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
CMS1_k127_3775733_2	1288298.rosmuc_00241	7.414e-177	556.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,46PGG@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1176 ABC-type spermidine putrescine transport system, permease component I	potH	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
CMS1_k127_3775733_1	314264.ROS217_09435	1.232e-213	667.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,46QII@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K11076	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	ABC_tran,TOBE_2
CMS1_k127_3775733_0	1354722.JQLS01000008_gene3547	9.059e-217	675.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TSUZ@28211|Alphaproteobacteria,46Q6M@74030|Roseovarius	28211|Alphaproteobacteria	P	Required for the activity of the bacterial periplasmic transport system of putrescine	potF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0019808,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_8
CMS1_k127_3775733_5	391613.RTM1035_18780	1.472e-124	402.0	COG1802@1|root,COG1802@2|Bacteria,1R4P5@1224|Proteobacteria,2U6CA@28211|Alphaproteobacteria,46PI4@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_3784372_2	1288298.rosmuc_02968	3.137e-69	236.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2U7JU@28211|Alphaproteobacteria,46S12@74030|Roseovarius	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
CMS1_k127_3784372_3	1288298.rosmuc_02969	4.264e-56	200.0	COG5500@1|root,COG5500@2|Bacteria,1N0PP@1224|Proteobacteria,2U7MA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
CMS1_k127_3784372_0	314264.ROS217_23027	2.036e-312	962.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,46P5A@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_3784372_1	1288298.rosmuc_02971	8.274e-101	333.0	COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,2U7DM@28211|Alphaproteobacteria,46Q5X@74030|Roseovarius	28211|Alphaproteobacteria	IQ	related to short-chain alcohol dehydrogenases	csgA	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_3784372_4	1342301.JASD01000008_gene1743	3.387e-34	134.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,3ZVZ9@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
CMS1_k127_3790333_0	351016.RAZWK3B_00785	2.333e-220	684.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2P2RP@2433|Roseobacter	28211|Alphaproteobacteria	H	Belongs to the N(4) N(6)-methyltransferase family	ccrM	-	2.1.1.72	ko:K13581	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS1_k127_3790333_3	1354722.JQLS01000008_gene3569	8.189e-124	402.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,46P6K@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS1_k127_3790333_2	391613.RTM1035_19296	7.22e-153	489.0	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,2TR7B@28211|Alphaproteobacteria,46NR8@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_3790333_1	1288298.rosmuc_00362	1.112e-154	490.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,46NH3@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
CMS1_k127_3790333_4	391595.RLO149_c039660	1.073e-08	57.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2TSXT@28211|Alphaproteobacteria,2P15P@2433|Roseobacter	28211|Alphaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_3793284_2	1288298.rosmuc_00150	2.597e-188	591.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria,46PUY@74030|Roseovarius	28211|Alphaproteobacteria	E	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS1_k127_3793284_1	1354722.JQLS01000008_gene3470	2.304e-203	636.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,46QD3@74030|Roseovarius	28211|Alphaproteobacteria	S	ATPase, AFG1 family protein	zapE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
CMS1_k127_3793284_3	1354722.JQLS01000008_gene3469	1.835e-175	558.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,46Q4R@74030|Roseovarius	28211|Alphaproteobacteria	V	COG1131 ABC-type multidrug transport system, ATPase component	yadG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3793284_4	1288298.rosmuc_00097	3.04e-31	126.0	COG4391@1|root,COG4391@2|Bacteria,1N7F4@1224|Proteobacteria,2UFVF@28211|Alphaproteobacteria,46RAG@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
CMS1_k127_3793284_0	1354722.JQLS01000008_gene3466	2.48e-300	926.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,46QCA@74030|Roseovarius	28211|Alphaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_3793449_3	89187.ISM_14750	1.203e-14	73.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,46NXY@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_3793449_1	314264.ROS217_21427	5.857e-140	447.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria,46P2R@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS1_k127_3793449_2	314264.ROS217_21432	1.143e-75	259.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria,46QSG@74030|Roseovarius	28211|Alphaproteobacteria	P	subunit of a heme lyase	cycL	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS1_k127_3793449_0	1288298.rosmuc_01282	5.452e-203	636.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,46PEE@74030|Roseovarius	28211|Alphaproteobacteria	O	COG1138 Cytochrome c biogenesis factor	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS1_k127_3801185_6	571166.KI421509_gene1874	1.029e-99	329.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_3801185_0	314264.ROS217_11986	1.845e-256	795.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,46NKP@74030|Roseovarius	28211|Alphaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_3801185_3	351016.RAZWK3B_03855	9.087e-174	555.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2P478@2433|Roseobacter	28211|Alphaproteobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_3801185_4	391613.RTM1035_16527	1.2e-134	431.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2TSQ4@28211|Alphaproteobacteria,46NB3@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_3801185_7	391613.RTM1035_16357	5.651e-45	166.0	2E2K9@1|root,32XPK@2|Bacteria,1N5WN@1224|Proteobacteria,2UE3V@28211|Alphaproteobacteria,46QX2@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3801185_1	351016.RAZWK3B_03860	5.706e-204	642.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2TQJY@28211|Alphaproteobacteria,2P2KM@2433|Roseobacter	28211|Alphaproteobacteria	C	glycerate kinase	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS1_k127_3801185_8	351016.RAZWK3B_03865	1.876e-44	166.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,2P3JI@2433|Roseobacter	28211|Alphaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS1_k127_3801185_2	314264.ROS217_12656	2.652e-203	637.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,46PR2@74030|Roseovarius	28211|Alphaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_3801185_5	391613.RTM1035_01900	8.12e-105	344.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2U703@28211|Alphaproteobacteria,46Q33@74030|Roseovarius	28211|Alphaproteobacteria	S	subfamily IA, variant 1	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_3802039_10	744980.TRICHSKD4_0600	2.199e-07	52.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2UD2W@28211|Alphaproteobacteria	1224|Proteobacteria	L	overlaps another CDS with the same product name	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
CMS1_k127_3802039_9	1530186.JQEY01000001_gene893	5.79e-13	68.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_3802039_3	314264.ROS217_19337	1.357e-110	364.0	2DBI1@1|root,2Z9E7@2|Bacteria,1QT4C@1224|Proteobacteria,2U2XD@28211|Alphaproteobacteria,46PHI@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2059
CMS1_k127_3802039_6	314264.ROS217_19342	3.213e-94	317.0	2EMFB@1|root,33F44@2|Bacteria,1RCQV@1224|Proteobacteria,2U82K@28211|Alphaproteobacteria,46PJD@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2059
CMS1_k127_3802039_4	89187.ISM_16140	1.779e-106	349.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,46NX1@74030|Roseovarius	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
CMS1_k127_3802039_8	1461693.ATO10_02505	7.546e-47	169.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS1_k127_3802039_5	1123360.thalar_01701	4.436e-95	316.0	COG1280@1|root,COG1280@2|Bacteria,1RAN1@1224|Proteobacteria,2U695@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_3802039_7	1354722.JQLS01000008_gene1262	7.626e-82	280.0	COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,2UG72@28211|Alphaproteobacteria,46Q5N@74030|Roseovarius	28211|Alphaproteobacteria	J	Including N-acetylases of ribosomal proteins	MA20_44020	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_3802039_1	83219.PM02_18865	2.362e-198	620.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,3ZUWR@60136|Sulfitobacter	28211|Alphaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS1_k127_3802039_2	1354722.JQLS01000008_gene1264	5.767e-194	610.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,46PCD@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS1_k127_3802039_0	1288298.rosmuc_01391	1.245e-233	727.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,46NQ0@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_380367_12	1354722.JQLS01000008_gene1122	9.64e-62	214.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,46PM4@74030|Roseovarius	28211|Alphaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS1_k127_380367_7	314264.ROS217_18387	3.419e-103	340.0	COG2518@1|root,COG2518@2|Bacteria,1R9VH@1224|Proteobacteria,2U8SI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,PCMT
CMS1_k127_380367_6	351016.RAZWK3B_10722	1.3e-107	364.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,2P0XH@2433|Roseobacter	28211|Alphaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS1_k127_380367_3	1354722.JQLS01000008_gene1120	6.805e-173	549.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2TTI5@28211|Alphaproteobacteria,46PVR@74030|Roseovarius	28211|Alphaproteobacteria	V	Beta-lactamase	nylB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_380367_10	351016.RAZWK3B_10707	1.181e-68	235.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2U9D3@28211|Alphaproteobacteria,2P3A6@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
CMS1_k127_380367_0	391613.RTM1035_10865	7.143e-263	812.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,46P23@74030|Roseovarius	28211|Alphaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_380367_5	1354722.JQLS01000008_gene1042	1.978e-112	365.0	COG0500@1|root,COG0500@2|Bacteria,1N0GG@1224|Proteobacteria,2UF0D@28211|Alphaproteobacteria,46QFD@74030|Roseovarius	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_380367_11	1354722.JQLS01000008_gene1041	2.242e-63	221.0	COG0454@1|root,COG0456@2|Bacteria,1RH0C@1224|Proteobacteria,2U9B4@28211|Alphaproteobacteria,46QVP@74030|Roseovarius	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	phnO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_380367_8	1354722.JQLS01000008_gene1040	5.529e-102	335.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2U7CH@28211|Alphaproteobacteria,46PNG@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS1_k127_380367_13	1354722.JQLS01000008_gene1039	6.936e-57	199.0	COG5416@1|root,COG5416@2|Bacteria,1Q4MJ@1224|Proteobacteria,2VB33@28211|Alphaproteobacteria,46QWQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Pfam:DUF1049	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
CMS1_k127_380367_14	391613.RTM1035_10890	1.373e-50	180.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,46R0G@74030|Roseovarius	28211|Alphaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_380367_4	1354722.JQLS01000008_gene1037	2.554e-168	535.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria,46NU7@74030|Roseovarius	28211|Alphaproteobacteria	F	COG1957 Inosine-uridine nucleoside N-ribohydrolase	rihA	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CMS1_k127_380367_9	1354722.JQLS01000008_gene1036	3.619e-74	251.0	COG0454@1|root,COG0456@2|Bacteria,1RDVI@1224|Proteobacteria,2U7V7@28211|Alphaproteobacteria,46QTY@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_380367_1	1354722.JQLS01000008_gene1035	4.663e-258	801.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,46Q12@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the UPF0061 (SELO) family	MA20_28420	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
CMS1_k127_380367_2	1354722.JQLS01000008_gene1034	5.537e-195	612.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,46QDE@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0513 Superfamily II DNA and RNA helicases	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_3825757_0	391613.RTM1035_18675	2.005e-217	682.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,46PDC@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_3825757_1	314264.ROS217_09560	1.288e-71	244.0	2B98H@1|root,322JR@2|Bacteria,1RIDC@1224|Proteobacteria,2UBDW@28211|Alphaproteobacteria,46P76@74030|Roseovarius	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
CMS1_k127_3839313_3	1123247.AUIJ01000008_gene2592	2.12e-07	57.0	2DM3J@1|root,31JTI@2|Bacteria,1RI2S@1224|Proteobacteria,2U27P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3839313_2	391589.RGAI101_4003	1.594e-08	59.0	2DGPJ@1|root,2ZWU6@2|Bacteria,1P7P5@1224|Proteobacteria,2UWYQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3839313_0	391589.RGAI101_4198	0.0	1362.0	COG1073@1|root,COG1926@1|root,COG2312@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,COG2312@2|Bacteria,1PIRD@1224|Proteobacteria,2V9HX@28211|Alphaproteobacteria,2P4V5@2433|Roseobacter	28211|Alphaproteobacteria	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS1_k127_3839313_1	391589.RGAI101_4098	6.59e-136	437.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2P1VQ@2433|Roseobacter	28211|Alphaproteobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_3866778_0	1288298.rosmuc_02255	3.898e-244	761.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TRCV@28211|Alphaproteobacteria,46PPI@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11,SPOR
CMS1_k127_3866778_1	391613.RTM1035_01520	1.116e-195	610.0	COG0715@1|root,COG0715@2|Bacteria,1MXA3@1224|Proteobacteria,2TQV6@28211|Alphaproteobacteria,46PAG@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	thiY	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_3868410_3	314264.ROS217_11536	1.271e-26	108.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,46PMC@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3868410_0	388399.SSE37_24509	2.766e-153	487.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3868410_1	766499.C357_22780	7.268e-95	314.0	COG3090@1|root,COG3090@2|Bacteria,1NK6X@1224|Proteobacteria,2TV38@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TRAP dicarboxylate transporter, DctQ subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_3868410_2	391619.PGA1_c12960	1.256e-54	193.0	COG1638@1|root,COG1638@2|Bacteria,1PG0D@1224|Proteobacteria,2TTUQ@28211|Alphaproteobacteria,34EVU@302485|Phaeobacter	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_3868410_4	388399.SSE37_24499	4.623e-21	92.0	COG1638@1|root,COG1638@2|Bacteria,1PG0D@1224|Proteobacteria,2TTUQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_3878054_7	314264.ROS217_08324	3.069e-33	128.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VG6E@28211|Alphaproteobacteria,46NU2@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, AsnC family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS1_k127_3878054_5	391613.RTM1035_17667	7.006e-183	580.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria,46PXP@74030|Roseovarius	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,FAD_oxidored,Lycopene_cycl,Trp_halogenase
CMS1_k127_3878054_3	1354722.JQLS01000008_gene3740	9.516e-230	715.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSX8@28211|Alphaproteobacteria,46Q0A@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1454 Alcohol dehydrogenase, class IV	mdh1	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS1_k127_3878054_0	314264.ROS217_08309	2.515e-279	863.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRJV@28211|Alphaproteobacteria,46NZQ@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	ssdA	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS1_k127_3878054_1	1354722.JQLS01000008_gene3738	5.992e-279	859.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TU6U@28211|Alphaproteobacteria,46PVF@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0174 Glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
CMS1_k127_3878054_4	1380367.JIBC01000004_gene2435	3.785e-206	643.0	COG4663@1|root,COG4663@2|Bacteria,1MUA1@1224|Proteobacteria,2TQS2@28211|Alphaproteobacteria,3ZVBA@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_3878054_2	89187.ISM_11435	1.597e-250	777.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,46Q8T@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	dctM1	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_3878054_6	1354722.JQLS01000008_gene3735	5.974e-77	259.0	COG4665@1|root,COG4665@2|Bacteria,1RDYM@1224|Proteobacteria,2TVMY@28211|Alphaproteobacteria,46QGY@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_3880044_1	926569.ANT_08240	3.81e-107	355.0	COG0473@1|root,COG0473@2|Bacteria,2G66J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.87	ko:K05824	ko00300,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map01100,map01120,map01130,map01210,map01230	M00030,M00433	R01934,R01936,R04862	RC00084,RC00114,RC00626	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_3880044_2	926569.ANT_08230	5.584e-74	253.0	COG0066@1|root,COG0066@2|Bacteria,2G6PB@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.114,4.2.1.33,4.2.1.35	ko:K01704,ko:K16793	ko00290,ko00300,ko00660,ko00680,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00680,map01100,map01110,map01120,map01130,map01210,map01230	M00432,M00433,M00535,M00608	R03444,R03896,R03898,R03968,R04001,R04371,R09720,R10170,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_3880044_0	926569.ANT_08220	7.299e-205	644.0	COG0065@1|root,COG0065@2|Bacteria,2G5IZ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.114,4.2.1.33,4.2.1.35	ko:K01703,ko:K16792	ko00290,ko00300,ko00660,ko00680,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00680,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00432,M00433,M00535,M00608	R03444,R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R09720,R10170,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS1_k127_3880044_3	926569.ANT_08210	1.013e-67	235.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_3896067_0	1288298.rosmuc_01528	0.0	1196.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,46PT6@74030|Roseovarius	28211|Alphaproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
CMS1_k127_3896067_1	1354722.JQLS01000008_gene1513	1.152e-308	953.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,46NBR@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS1_k127_3896067_2	1354722.JQLS01000008_gene1512	3.363e-266	825.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,46P1B@74030|Roseovarius	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS1_k127_3896067_3	89187.ISM_17220	8.028e-22	96.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,46NTI@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0340 Biotin-(acetyl-CoA carboxylase) ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2
CMS1_k127_3925365_0	1354722.JQLS01000008_gene214	0.0	3156.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,2UR2U@28211|Alphaproteobacteria,46NBF@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG3321 Polyketide synthase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
CMS1_k127_3925712_1	314264.ROS217_13746	6.741e-150	478.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,46PA3@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS1_k127_3925712_0	314264.ROS217_13751	4.763e-247	767.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,46PC6@74030|Roseovarius	28211|Alphaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS1_k127_3925712_2	1354722.JQLS01000008_gene259	6.08e-105	343.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,46QJ3@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
CMS1_k127_3925712_3	1354722.JQLS01000008_gene260	3.895e-42	155.0	COG3637@1|root,COG3637@2|Bacteria,1RBBG@1224|Proteobacteria,2U5ED@28211|Alphaproteobacteria,46RJF@74030|Roseovarius	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	lpxQ	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl
CMS1_k127_393023_4	1288298.rosmuc_01856	2.297e-70	238.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,46PDJ@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_393023_2	1288298.rosmuc_01855	2.793e-152	486.0	28H9Q@1|root,2Z7MC@2|Bacteria,1N3UI@1224|Proteobacteria,2TTXB@28211|Alphaproteobacteria,46Q3T@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_393023_3	314264.ROS217_14056	1.279e-141	462.0	COG3568@1|root,COG3568@2|Bacteria,1QV2C@1224|Proteobacteria,2U065@28211|Alphaproteobacteria,46QEJ@74030|Roseovarius	28211|Alphaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_393023_1	314264.ROS217_14051	5.091e-219	689.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,46PHB@74030|Roseovarius	28211|Alphaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_393023_0	1354722.JQLS01000008_gene2547	6.019e-315	967.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46NG5@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	aldB	-	-	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	-	R00711	RC00047	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_393023_5	1288298.rosmuc_01851	1.8e-15	76.0	COG3284@1|root,COG3284@2|Bacteria,1MVRZ@1224|Proteobacteria,2TSRW@28211|Alphaproteobacteria,46QBX@74030|Roseovarius	28211|Alphaproteobacteria	KQ	COG3284 Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8
CMS1_k127_3937084_3	314264.ROS217_04585	1.764e-27	111.0	COG0457@1|root,COG0457@2|Bacteria,1RFAH@1224|Proteobacteria,2U7KD@28211|Alphaproteobacteria,46QTV@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_16,TPR_2,TPR_8
CMS1_k127_3937084_1	1288298.rosmuc_01727	1.889e-162	514.0	COG0457@1|root,COG0457@2|Bacteria,1MUW4@1224|Proteobacteria,2TRAE@28211|Alphaproteobacteria,46PFY@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
CMS1_k127_3937084_2	391613.RTM1035_14557	2.205e-79	267.0	COG4960@1|root,COG4960@2|Bacteria,1RDMM@1224|Proteobacteria,2U7NB@28211|Alphaproteobacteria,46NMC@74030|Roseovarius	28211|Alphaproteobacteria	OU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
CMS1_k127_3937084_0	1288298.rosmuc_01725	3.401e-246	763.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,2TTA9@28211|Alphaproteobacteria,46NVX@74030|Roseovarius	28211|Alphaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3950189_4	1288298.rosmuc_00619	1.125e-88	295.0	COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,46PKY@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	SH3_4
CMS1_k127_3950189_3	644107.SL1157_1719	5.85e-175	559.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,4NBPP@97050|Ruegeria	28211|Alphaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	gyaR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_3950189_2	314264.ROS217_07764	3.926e-186	587.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2TSWI@28211|Alphaproteobacteria,46Q3V@74030|Roseovarius	28211|Alphaproteobacteria	L	N6-adenine-specific DNA methylase	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	THUMP,UPF0020
CMS1_k127_3950189_1	314264.ROS217_07759	1.503e-292	913.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,46NX4@74030|Roseovarius	28211|Alphaproteobacteria	M	Gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_3950189_5	391613.RTM1035_20571	9.139e-65	226.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2U98F@28211|Alphaproteobacteria,46QV2@74030|Roseovarius	28211|Alphaproteobacteria	K	helix_turn_helix, mercury resistance	cueR	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS1_k127_3950189_0	314264.ROS217_07749	0.0	1079.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,46QG0@74030|Roseovarius	28211|Alphaproteobacteria	P	haloacid dehalogenase-like hydrolase	actP	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_3975889_6	1288298.rosmuc_03712	1.378e-28	117.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,46NAX@74030|Roseovarius	28211|Alphaproteobacteria	E	Aminotransferase, class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_3975889_1	1288298.rosmuc_03711	0.0	1034.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,2TQR4@28211|Alphaproteobacteria,46PW0@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	betS	-	-	ko:K03451	-	-	-	-	ko00000	2.A.15	-	-	BCCT
CMS1_k127_3975889_0	1354722.JQLS01000008_gene1338	0.0	1079.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,2TQR4@28211|Alphaproteobacteria,46QHD@74030|Roseovarius	28211|Alphaproteobacteria	P	BCCT, betaine/carnitine/choline family transporter	opuD	-	-	-	-	-	-	-	-	-	-	-	BCCT
CMS1_k127_3975889_5	1469613.JT55_10425	4.333e-30	120.0	COG4321@1|root,COG4321@2|Bacteria,1N7Z2@1224|Proteobacteria,2UF7W@28211|Alphaproteobacteria,3FDI9@34008|Rhodovulum	28211|Alphaproteobacteria	S	Ribbon-helix-helix domain	MA20_02235	-	-	-	-	-	-	-	-	-	-	-	RHH_4
CMS1_k127_3975889_2	1002340.AFCF01000060_gene506	6.157e-280	863.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,34F7P@302485|Phaeobacter	28211|Alphaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS1_k127_3975889_4	351016.RAZWK3B_14384	3.295e-74	251.0	COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,2P319@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_02250	-	-	ko:K09985	-	-	-	-	ko00000	-	-	-	SspB
CMS1_k127_3975889_3	1288298.rosmuc_03705	1.494e-179	569.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,46P0E@74030|Roseovarius	28211|Alphaproteobacteria	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CMS1_k127_3978945_1	1354722.JQLS01000008_gene609	1.589e-44	163.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,46PMV@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_3978945_0	1288298.rosmuc_03110	8.203e-213	668.0	COG3409@1|root,COG3409@2|Bacteria,1QCG0@1224|Proteobacteria,2U0WT@28211|Alphaproteobacteria,46QKY@74030|Roseovarius	28211|Alphaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
CMS1_k127_3992668_5	644076.SCH4B_0754	1.598e-12	69.0	2EGAY@1|root,33A2T@2|Bacteria,1NNB4@1224|Proteobacteria,2UJNS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3992668_1	314264.ROS217_21837	3.405e-283	874.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,46PG8@74030|Roseovarius	28211|Alphaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS1_k127_3992668_2	391613.RTM1035_11670	6.142e-240	746.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,46NQ2@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1520 FOG WD40-like repeat	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS1_k127_3992668_4	1354722.JQLS01000008_gene1812	1.79e-89	302.0	COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,46P5I@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
CMS1_k127_3992668_3	1354722.JQLS01000008_gene1813	7.081e-173	552.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,2TRSC@28211|Alphaproteobacteria,46QDU@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_3992668_0	391613.RTM1035_11685	0.0	1077.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,46PY1@74030|Roseovarius	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	ttgE	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
CMS1_k127_399363_4	375451.RD1_0448	8.467e-76	258.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2P1SE@2433|Roseobacter	28211|Alphaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS1_k127_399363_2	644076.SCH4B_3172	1.924e-101	332.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,4NA5Q@97050|Ruegeria	28211|Alphaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS1_k127_399363_1	314264.ROS217_10597	1.321e-185	586.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TUDF@28211|Alphaproteobacteria,46PIS@74030|Roseovarius	28211|Alphaproteobacteria	S	Peptidase dimerisation domain	celE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_399363_5	89187.ISM_06815	4.554e-62	214.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,46QVX@74030|Roseovarius	28211|Alphaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_399363_0	1354722.JQLS01000008_gene3165	0.0	1686.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,46Q8I@74030|Roseovarius	28211|Alphaproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS1_k127_399363_3	391613.RTM1035_17407	4.906e-92	305.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,46NNV@74030|Roseovarius	28211|Alphaproteobacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
CMS1_k127_4008990_0	351016.RAZWK3B_03740	1.656e-277	858.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2P26K@2433|Roseobacter	28211|Alphaproteobacteria	E	COG2303 Choline dehydrogenase and related flavoproteins	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_4033290_9	1122614.JHZF01000013_gene4094	1.501e-45	165.0	COG2082@1|root,COG2082@2|Bacteria,1MX1E@1224|Proteobacteria,2TRRB@28211|Alphaproteobacteria,2PCVV@252301|Oceanicola	28211|Alphaproteobacteria	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
CMS1_k127_4033290_1	1354722.JQLS01000008_gene331	6.939e-236	732.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,2TRR5@28211|Alphaproteobacteria,46PPS@74030|Roseovarius	28211|Alphaproteobacteria	H	COG2241 Precorrin-6B methylase 1	cobL	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	PCMT,TP_methylase
CMS1_k127_4033290_7	314231.FP2506_09356	3.643e-82	279.0	COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,2TTJH@28211|Alphaproteobacteria,2PKGZ@255475|Aurantimonadaceae	28211|Alphaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
CMS1_k127_4033290_0	391613.RTM1035_02950	0.0	1011.0	COG1010@1|root,COG2073@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,1MU79@1224|Proteobacteria,2TQJQ@28211|Alphaproteobacteria,46NC6@74030|Roseovarius	28211|Alphaproteobacteria	H	Cobalamin synthesis G C-terminus	cobJ	-	2.1.1.131,3.7.1.12	ko:K05934,ko:K13541	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R07772	RC00003,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,TP_methylase
CMS1_k127_4033290_4	391613.RTM1035_02955	1.221e-147	470.0	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,2TRU7@28211|Alphaproteobacteria,46QIZ@74030|Roseovarius	28211|Alphaproteobacteria	H	COG2875 Precorrin-4 methylase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
CMS1_k127_4033290_5	1122180.Lokhon_01132	1.226e-104	351.0	COG0329@1|root,COG0329@2|Bacteria,1MU77@1224|Proteobacteria,2TTNF@28211|Alphaproteobacteria,2P9J7@245186|Loktanella	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	dapAch3	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_4033290_2	246200.SPO3220	6.893e-175	556.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2TR29@28211|Alphaproteobacteria,4NAF3@97050|Ruegeria	28211|Alphaproteobacteria	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_4033290_6	1354722.JQLS01000008_gene506	3.73e-99	324.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,46NXV@74030|Roseovarius	28211|Alphaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630	-	R00653	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	Pep_deformylase
CMS1_k127_4033290_8	1123237.Salmuc_03007	5.363e-77	260.0	COG0242@1|root,COG0242@2|Bacteria,1R9X9@1224|Proteobacteria,2U5GY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def1	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_4033290_3	1288298.rosmuc_02488	7.434e-156	497.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,46P7S@74030|Roseovarius	28211|Alphaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_4033290_10	1354722.JQLS01000008_gene509	4.888e-41	154.0	2C0W4@1|root,32RWF@2|Bacteria,1N0P0@1224|Proteobacteria,2UBUE@28211|Alphaproteobacteria,46R5V@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4033290_11	1354722.JQLS01000008_gene510	3.158e-32	126.0	COG2261@1|root,COG2261@2|Bacteria,1N8MR@1224|Proteobacteria,2UFAZ@28211|Alphaproteobacteria,46R6K@74030|Roseovarius	28211|Alphaproteobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS1_k127_4033290_12	1288298.rosmuc_02491	2.083e-28	115.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6B7@28211|Alphaproteobacteria,46PX5@74030|Roseovarius	28211|Alphaproteobacteria	S	UPF0126 domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0126
CMS1_k127_4037327_2	314264.ROS217_09350	1.803e-100	328.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,46NG8@74030|Roseovarius	28211|Alphaproteobacteria	E	COG2515 1-aminocyclopropane-1-carboxylate deaminase	cuyA	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0034011,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	4.4.1.15,4.4.1.25	ko:K05396,ko:K17950	ko00270,map00270	-	R01874,R07634	RC00382,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
CMS1_k127_4037327_0	314264.ROS217_09355	0.0	1440.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,46NIF@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS1_k127_4037327_3	1305735.JAFT01000005_gene3761	1.571e-83	278.0	28NR0@1|root,2ZBQD@2|Bacteria,1RA2I@1224|Proteobacteria,2U5BA@28211|Alphaproteobacteria,2PE06@252301|Oceanicola	28211|Alphaproteobacteria	S	Nucleoside 2-deoxyribosyltransferase YtoQ	ytoQ	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyri_tr3
CMS1_k127_4037327_1	314264.ROS217_10002	1.801e-228	709.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,46QCA@74030|Roseovarius	28211|Alphaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_4039494_0	1354722.JQLS01000008_gene1740	3.275e-315	970.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria,46PGY@74030|Roseovarius	28211|Alphaproteobacteria	S	hydrolase of the metallo-beta-lactamase superfamily	rnjA	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
CMS1_k127_4039494_1	1288298.rosmuc_01315	8.476e-158	498.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2TS5A@28211|Alphaproteobacteria,46PCJ@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS1_k127_4039494_2	391613.RTM1035_09975	1.114e-52	188.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,46NTI@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0340 Biotin-(acetyl-CoA carboxylase) ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2
CMS1_k127_406338_0	1354722.JQLS01000008_gene2587	1.535e-271	839.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,46NKE@74030|Roseovarius	28211|Alphaproteobacteria	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS1_k127_406338_1	391613.RTM1035_15217	1.545e-146	475.0	COG1215@1|root,COG1215@2|Bacteria,1Q98P@1224|Proteobacteria,2V7PV@28211|Alphaproteobacteria,46P4H@74030|Roseovarius	28211|Alphaproteobacteria	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_406338_2	314264.ROS217_06464	1.111e-43	160.0	COG0697@1|root,COG0697@2|Bacteria,1PS60@1224|Proteobacteria,2V4D9@28211|Alphaproteobacteria,46QJI@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4072931_3	1288298.rosmuc_03500	1.37e-20	93.0	29TS5@1|root,30F0D@2|Bacteria,1RFIN@1224|Proteobacteria,2UKV7@28211|Alphaproteobacteria,46QTH@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4072931_2	314264.ROS217_18297	5.632e-98	323.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2TVD3@28211|Alphaproteobacteria,46QKR@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_4072931_0	391613.RTM1035_10445	3.065e-224	699.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,46P7N@74030|Roseovarius	28211|Alphaproteobacteria	E	Apparently involved in regulation of cell wall biogenesis	rfbE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4072931_1	391613.RTM1035_10440	3.565e-121	390.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,46QDK@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	ordL	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
CMS1_k127_4085932_5	1002340.AFCF01000052_gene1536	3.808e-44	160.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,34DWY@302485|Phaeobacter	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	dhaL	-	1.2.1.99	ko:K09472	ko00330,ko01100,map00330,map01100	M00136	R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_4085932_2	314264.ROS217_23092	1.733e-215	676.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2U2FB@28211|Alphaproteobacteria,46Q68@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_4085932_4	1446473.JHWH01000021_gene3097	3.185e-121	396.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2TVJW@28211|Alphaproteobacteria,2PZ4U@265|Paracoccus	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.304,1.1.1.76	ko:K18009	ko00650,map00650	-	R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_4085932_3	981384.AEYW01000006_gene2988	2.519e-131	421.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TVE6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_4085932_0	985054.JQEZ01000001_gene2945	8.413e-305	940.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,2TR0V@28211|Alphaproteobacteria,4ND82@97050|Ruegeria	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_4085932_6	1267533.KB906734_gene4079	3.668e-30	130.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	algA	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_4085932_1	314264.ROS217_21347	1.211e-301	929.0	COG5598@1|root,COG5598@2|Bacteria,1N18H@1224|Proteobacteria,2TRUE@28211|Alphaproteobacteria,46NSY@74030|Roseovarius	28211|Alphaproteobacteria	H	COG5598 Trimethylamine corrinoid methyltransferase	mttB2	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_408904_6	644076.SCH4B_1745	1.7e-06	58.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,4NBPW@97050|Ruegeria	28211|Alphaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS1_k127_408904_5	1354722.JQLS01000008_gene1140	4.967e-60	208.0	293EG@1|root,2ZQWX@2|Bacteria,1RDP4@1224|Proteobacteria,2U79J@28211|Alphaproteobacteria,46QVW@74030|Roseovarius	28211|Alphaproteobacteria	S	Elongation factor P	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_408904_0	391613.RTM1035_07153	7.986e-268	829.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2TRHI@28211|Alphaproteobacteria,46NMF@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CMS1_k127_408904_3	314264.ROS217_21707	1.325e-62	227.0	2E3RB@1|root,32YP1@2|Bacteria,1N8H0@1224|Proteobacteria,2UF62@28211|Alphaproteobacteria,46QPP@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_408904_1	1354722.JQLS01000008_gene1137	3.584e-214	674.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,46NEW@74030|Roseovarius	28211|Alphaproteobacteria	MU	Type I secretion outer membrane protein, TolC family	bepC	-	-	ko:K12340,ko:K12535	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00327,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_408904_2	391613.RTM1035_07138	1.538e-115	374.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2U704@28211|Alphaproteobacteria,46NK5@74030|Roseovarius	28211|Alphaproteobacteria	O	COG2518 Protein-L-isoaspartate carboxylmethyltransferase	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_408904_7	190650.CC_2380	0.000108	48.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS1_k127_408904_4	1354722.JQLS01000008_gene1133	2.378e-61	211.0	COG1525@1|root,COG1525@2|Bacteria,1N52A@1224|Proteobacteria,2UE7Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4100468_0	1354722.JQLS01000008_gene1807	9.271e-188	590.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,46PU7@74030|Roseovarius	28211|Alphaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS1_k127_4100468_2	391589.RGAI101_1785	4.795e-46	181.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U9Q1@28211|Alphaproteobacteria,2P3FH@2433|Roseobacter	28211|Alphaproteobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_4100468_1	314264.ROS217_21817	3.818e-47	170.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,46R0P@74030|Roseovarius	28211|Alphaproteobacteria	U	translocase subunit yajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS1_k127_4100468_3	1354722.JQLS01000008_gene1805	1.184e-18	86.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,46P1R@74030|Roseovarius	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_4110083_1	391624.OIHEL45_20801	3.493e-52	187.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TVC4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_4110083_0	1123247.AUIJ01000004_gene1159	0.0	1097.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1P31Y@1224|Proteobacteria,2TQTU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS1_k127_4124135_1	1288298.rosmuc_02638	6.824e-158	505.0	2CADT@1|root,2Z8FB@2|Bacteria,1NFWD@1224|Proteobacteria,2TSJ0@28211|Alphaproteobacteria,46PFZ@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4124135_0	1354722.JQLS01000008_gene1899	4.82e-293	902.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,46PFI@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	MA20_29420	-	6.2.1.48	ko:K00666,ko:K02182	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_414287_0	1354722.JQLS01000005_gene3922	5.711e-284	874.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2TSSN@28211|Alphaproteobacteria,46NNT@74030|Roseovarius	28211|Alphaproteobacteria	E	Orn/Lys/Arg decarboxylase, C-terminal domain	-	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
CMS1_k127_414287_1	1354722.JQLS01000005_gene3923	2.171e-204	638.0	COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,2TTKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_416244_1	1354722.JQLS01000008_gene1194	7.313e-89	297.0	COG1171@1|root,COG1171@2|Bacteria,1QVNS@1224|Proteobacteria,2TUHW@28211|Alphaproteobacteria,46PYM@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1171 Threonine dehydratase	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
CMS1_k127_416244_0	391613.RTM1035_10180	8.293e-187	592.0	COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,2TVVP@28211|Alphaproteobacteria,46PZN@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0006 Xaa-Pro aminopeptidase	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_418941_12	391613.RTM1035_09518	1.502e-14	73.0	COG4233@1|root,COG4233@2|Bacteria,1REVE@1224|Proteobacteria,2VEXK@28211|Alphaproteobacteria,46QFN@74030|Roseovarius	28211|Alphaproteobacteria	CO	to be involved in C-type cytochrome biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CMS1_k127_418941_4	1288298.rosmuc_01343	6.711e-162	512.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2TQY8@28211|Alphaproteobacteria,46NB1@74030|Roseovarius	28211|Alphaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CMS1_k127_418941_9	1354722.JQLS01000008_gene1611	6.649e-66	228.0	COG1714@1|root,COG1714@2|Bacteria,1P9TI@1224|Proteobacteria,2TRIS@28211|Alphaproteobacteria,46QSA@74030|Roseovarius	28211|Alphaproteobacteria	S	RDD family	MA20_36685	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_418941_8	351016.RAZWK3B_13499	1.776e-66	234.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria,2P52H@2433|Roseobacter	28211|Alphaproteobacteria	S	Aminoacyl-tRNA editing domain	ybaK	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS1_k127_418941_0	314264.ROS217_21142	0.0	1508.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,46QD8@74030|Roseovarius	28211|Alphaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS1_k127_418941_10	1354722.JQLS01000008_gene1608	2.23e-37	141.0	2E8MM@1|root,332Z2@2|Bacteria,1N74Q@1224|Proteobacteria,2UFS8@28211|Alphaproteobacteria,46R7Q@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_418941_6	1354722.JQLS01000008_gene1607	4.426e-83	281.0	2AW2D@1|root,31MX4@2|Bacteria,1RI14@1224|Proteobacteria,2U9Z1@28211|Alphaproteobacteria,46P4J@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_418941_3	1288298.rosmuc_01349	1.596e-201	632.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2TUNR@28211|Alphaproteobacteria,46QG6@74030|Roseovarius	28211|Alphaproteobacteria	J	SAM-dependent methyltransferases	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_418941_5	1354722.JQLS01000008_gene1605	2.869e-84	286.0	COG1569@1|root,COG1569@2|Bacteria,1RCZE@1224|Proteobacteria,2U5DQ@28211|Alphaproteobacteria,46Q8Q@74030|Roseovarius	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
CMS1_k127_418941_1	1288298.rosmuc_01351	5.565e-245	758.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,46P6R@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_01305	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_418941_11	1288298.rosmuc_01352	6.307e-21	92.0	2AJGR@1|root,31A36@2|Bacteria,1Q4U8@1224|Proteobacteria,2VB95@28211|Alphaproteobacteria,46R8U@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_418941_2	391613.RTM1035_09434	1.855e-233	730.0	2BWZZ@1|root,2Z7V7@2|Bacteria,1PFGK@1224|Proteobacteria,2TUWA@28211|Alphaproteobacteria,46NGV@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2927)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2927
CMS1_k127_418941_7	1288298.rosmuc_01354	4.555e-77	258.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria,46Q3E@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0714 MoxR-like ATPases	MA20_01295	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS1_k127_4194159_3	1449350.OCH239_05005	0.0003251	52.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,4KK1D@93682|Roseivivax	28211|Alphaproteobacteria	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS1_k127_4194159_0	1354722.JQLS01000008_gene523	1.267e-249	775.0	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,2TQM3@28211|Alphaproteobacteria,46NHD@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3562 Capsule polysaccharide export protein	kpsS	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS1_k127_4194159_1	1288298.rosmuc_01919	2.002e-206	647.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2TS5Q@28211|Alphaproteobacteria,46QE9@74030|Roseovarius	28211|Alphaproteobacteria	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_4194159_2	391613.RTM1035_13703	5.47e-193	608.0	COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,2TTAJ@28211|Alphaproteobacteria,46PG2@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3563 Capsule polysaccharide export protein	kpsC	-	-	ko:K07266	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS1_k127_4209679_0	89187.ISM_16910	0.0	1599.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria,46PHS@74030|Roseovarius	28211|Alphaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
CMS1_k127_4210218_1	314264.ROS217_10297	5.452e-194	608.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,46Q4E@74030|Roseovarius	28211|Alphaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,AAA_23,SMC_N
CMS1_k127_4210218_0	314264.ROS217_10302	8.049e-227	706.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,46P2Q@74030|Roseovarius	28211|Alphaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS1_k127_4212648_2	1354722.JQLS01000008_gene473	7.86e-112	362.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2U7CZ@28211|Alphaproteobacteria,46Q3F@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2853 Surface lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CMS1_k127_4212648_3	314264.ROS217_04130	4.746e-100	332.0	COG2854@1|root,COG2854@2|Bacteria,1PDBV@1224|Proteobacteria,2U5HR@28211|Alphaproteobacteria,46NQI@74030|Roseovarius	28211|Alphaproteobacteria	Q	involved in resistance to organic solvents, auxiliary component	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS1_k127_4212648_0	1354722.JQLS01000008_gene475	0.0	1144.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,46QHZ@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0744 Membrane carboxypeptidase (penicillin-binding protein)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS1_k127_4212648_4	1354722.JQLS01000008_gene476	1.241e-62	218.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,46QXN@74030|Roseovarius	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS1_k127_4212648_1	89187.ISM_08960	1.102e-239	745.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,46Q28@74030|Roseovarius	28211|Alphaproteobacteria	P	Ammonium transporter	amt_1	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_4212648_5	314264.ROS217_04105	1.465e-55	199.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,46Q3J@74030|Roseovarius	28211|Alphaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_4233368_4	1288298.rosmuc_01997	2.247e-130	418.0	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,2TS5K@28211|Alphaproteobacteria,46P3B@74030|Roseovarius	28211|Alphaproteobacteria	S	Haloacid dehalogenase, type II	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
CMS1_k127_4233368_3	314264.ROS217_15480	4.165e-138	446.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,46N9V@74030|Roseovarius	28211|Alphaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_4233368_1	314264.ROS217_15475	9.437e-176	559.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,46QET@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1171 Threonine dehydratase	tdcB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_4233368_2	1354722.JQLS01000008_gene2166	5.125e-141	450.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,46PYE@74030|Roseovarius	28211|Alphaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	pcaD	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_4233368_0	1354722.JQLS01000008_gene2167	4.04e-181	578.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria,46P1X@74030|Roseovarius	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4234314_1	1354722.JQLS01000008_gene3138	1.317e-142	454.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,46Q3D@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_4234314_0	391613.RTM1035_17467	7.983e-202	631.0	COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,2TQU8@28211|Alphaproteobacteria,46NJR@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	opgH	GO:0005575,GO:0016020	-	ko:K03669	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.3.1.1	GT2	-	Glyco_trans_2_3
CMS1_k127_4236600_6	1002340.AFCF01000064_gene162	8.018e-25	111.0	COG2771@1|root,COG2771@2|Bacteria	2|Bacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_4236600_2	1353537.TP2_16250	4.931e-140	448.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2TS2V@28211|Alphaproteobacteria,2XMJ0@285107|Thioclava	28211|Alphaproteobacteria	U	ABC 3 transport family	sitD	-	-	ko:K02075,ko:K11606,ko:K11708,ko:K11709	ko02010,map02010	M00244,M00317,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	-	ABC-3
CMS1_k127_4236600_1	1353537.TP2_16245	1.352e-153	488.0	COG1108@1|root,COG1108@2|Bacteria,1MY5X@1224|Proteobacteria,2TQXB@28211|Alphaproteobacteria,2XN1F@285107|Thioclava	28211|Alphaproteobacteria	U	ABC 3 transport family	sitC	-	-	ko:K11605	ko02010,map02010	M00317	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.7,3.A.1.15.9	-	-	ABC-3
CMS1_k127_4236600_0	1353537.TP2_16240	1.136e-158	504.0	COG1121@1|root,COG1121@2|Bacteria,1MW47@1224|Proteobacteria,2TRJA@28211|Alphaproteobacteria,2XKMA@285107|Thioclava	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	yfeB	-	-	ko:K11607	ko02010,map02010	M00317	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
CMS1_k127_4236600_3	1238450.VIBNISOn1_1530049	2.397e-121	399.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1RRM3@1236|Gammaproteobacteria,1XSRU@135623|Vibrionales	135623|Vibrionales	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K11604	ko02010,map02010	M00317	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.7,3.A.1.15.9	-	-	ZnuA
CMS1_k127_4236600_4	1353537.TP2_16230	1.104e-70	246.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,2XNEC@285107|Thioclava	28211|Alphaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_4236600_5	1415756.JQMY01000001_gene2136	4.336e-39	158.0	COG3021@1|root,COG3021@2|Bacteria,1PXAX@1224|Proteobacteria,2U95T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_4240529_1	1288298.rosmuc_02005	1.509e-37	141.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,46QCP@74030|Roseovarius	28211|Alphaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS1_k127_4240529_0	375451.RD1_2923	2.474e-149	479.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2U1FU@28211|Alphaproteobacteria,2P2NU@2433|Roseobacter	28211|Alphaproteobacteria	K	helix_turn _helix lactose operon repressor	purR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CMS1_k127_4240529_2	375451.RD1_2922	5.132e-30	120.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2P27H@2433|Roseobacter	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_4244527_2	1288298.rosmuc_03698	2.06e-153	486.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,46QIY@74030|Roseovarius	28211|Alphaproteobacteria	T	Containing CheY-like receiver, AAA-type ATPase, and DNA-binding	dctD	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_4244527_0	1354722.JQLS01000008_gene1324	5.311e-308	951.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,46QK5@74030|Roseovarius	28211|Alphaproteobacteria	T	COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system	dctB	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1,dCache_3
CMS1_k127_4244527_3	391613.RTM1035_07749	6.082e-127	409.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,46P62@74030|Roseovarius	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CMS1_k127_4244527_4	314264.ROS217_19597	2.888e-37	142.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,46R5S@74030|Roseovarius	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
CMS1_k127_4244527_1	1354722.JQLS01000008_gene1321	7.364e-162	511.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,46PJG@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS1_k127_4267970_3	314264.ROS217_21482	9.778e-170	535.0	COG0583@1|root,COG0583@2|Bacteria,1MV5N@1224|Proteobacteria,2TRAX@28211|Alphaproteobacteria,46P66@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	MA20_05050	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4267970_0	391613.RTM1035_10170	0.0	2000.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,46NG1@74030|Roseovarius	28211|Alphaproteobacteria	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
CMS1_k127_4267970_5	1354722.JQLS01000008_gene1198	2.054e-148	473.0	COG0204@1|root,COG0204@2|Bacteria,1QU3F@1224|Proteobacteria,2U1AI@28211|Alphaproteobacteria,46P8U@74030|Roseovarius	28211|Alphaproteobacteria	I	Acyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS1_k127_4267970_4	351016.RAZWK3B_14249	2.34e-155	493.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,2P2NT@2433|Roseobacter	28211|Alphaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CMS1_k127_4267970_1	314264.ROS217_21462	3.468e-201	629.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,46Q60@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_4267970_7	314264.ROS217_21457	6.548e-79	265.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,46NG6@74030|Roseovarius	28211|Alphaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CMS1_k127_4267970_6	1354722.JQLS01000008_gene1202	2.955e-103	338.0	COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,46QFZ@74030|Roseovarius	28211|Alphaproteobacteria	S	secretion activating protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
CMS1_k127_4267970_8	391624.OIHEL45_14275	1.121e-66	234.0	29KAU@1|root,30784@2|Bacteria,1RCW8@1224|Proteobacteria,2U783@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Holin of 3TMs, for gene-transfer release	-	-	-	-	-	-	-	-	-	-	-	-	GTA_holin_3TM
CMS1_k127_4267970_2	391613.RTM1035_10135	2.164e-199	623.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,46PEE@74030|Roseovarius	28211|Alphaproteobacteria	O	COG1138 Cytochrome c biogenesis factor	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS1_k127_4280464_3	1288298.rosmuc_01520	2.195e-102	335.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,46PER@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
CMS1_k127_4280464_6	1354722.JQLS01000008_gene1520	1.507e-56	200.0	2ANT7@1|root,31DTG@2|Bacteria,1RHPB@1224|Proteobacteria,2U9BN@28211|Alphaproteobacteria,46QZD@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4280464_0	314264.ROS217_20677	5.035e-212	661.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,46Q3G@74030|Roseovarius	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS1_k127_4280464_1	89187.ISM_14360	7.63e-132	424.0	2E74C@1|root,331NT@2|Bacteria,1N6SD@1224|Proteobacteria,2UKV2@28211|Alphaproteobacteria,46R42@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
CMS1_k127_4280464_2	351016.RAZWK3B_13399	1.389e-106	345.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,2P226@2433|Roseobacter	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3,1.6.99.3	ko:K00338,ko:K03941	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	Fer4
CMS1_k127_4280464_5	1354722.JQLS01000008_gene1517	3.969e-72	246.0	COG0599@1|root,COG0599@2|Bacteria,1RD2R@1224|Proteobacteria,2U76K@28211|Alphaproteobacteria,46QPQ@74030|Roseovarius	28211|Alphaproteobacteria	S	homolog of gamma-carboxymuconolactone decarboxylase subunit	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
CMS1_k127_4280464_4	314264.ROS217_20662	1.651e-74	255.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,46NZ4@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS1_k127_4285293_2	1342301.JASD01000006_gene73	2.001e-19	89.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,3ZY3P@60136|Sulfitobacter	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
CMS1_k127_4285293_3	314262.MED193_08278	1.875e-12	70.0	COG0582@1|root,COG0582@2|Bacteria,1PTZ1@1224|Proteobacteria,2U1YG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_4285293_0	391613.RTM1035_18005	2.955e-175	553.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,46NBS@74030|Roseovarius	28211|Alphaproteobacteria	C	NmrA-like family	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
CMS1_k127_4285293_1	1354722.JQLS01000008_gene3292	6.53e-65	224.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,46PS2@74030|Roseovarius	28211|Alphaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	GO:0008150,GO:0042221,GO:0046677,GO:0050896	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS1_k127_4301819_7	314264.ROS217_12276	1.402e-23	100.0	COG3197@1|root,COG3197@2|Bacteria,1Q4US@1224|Proteobacteria,2VB9J@28211|Alphaproteobacteria,46R9N@74030|Roseovarius	28211|Alphaproteobacteria	P	Cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS1_k127_4301819_0	1354722.JQLS01000008_gene167	0.0	1184.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,46P5B@74030|Roseovarius	28211|Alphaproteobacteria	P	P-type ATPase	fixI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_4301819_5	391613.RTM1035_01500	1.692e-74	252.0	COG5456@1|root,COG5456@2|Bacteria,1RHKI@1224|Proteobacteria,2U9GB@28211|Alphaproteobacteria,46QQ6@74030|Roseovarius	28211|Alphaproteobacteria	P	FixH	fixH	-	-	-	-	-	-	-	-	-	-	-	FixH
CMS1_k127_4301819_1	351016.RAZWK3B_06112	2.407e-286	882.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria,2P1FI@2433|Roseobacter	28211|Alphaproteobacteria	C	Iron-sulfur-binding protein, RdxA RdxB FixG family	ccoG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS1_k127_4301819_3	1354722.JQLS01000008_gene164	1.74e-150	479.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TUTH@28211|Alphaproteobacteria,46P0S@74030|Roseovarius	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4301819_2	1288298.rosmuc_02248	1.288e-159	505.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,46Q1B@74030|Roseovarius	28211|Alphaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS1_k127_4301819_6	351016.RAZWK3B_06097	7.006e-24	103.0	COG4736@1|root,COG4736@2|Bacteria,1N7ZG@1224|Proteobacteria,2UFMC@28211|Alphaproteobacteria,2P3XW@2433|Roseobacter	28211|Alphaproteobacteria	C	Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
CMS1_k127_4301819_4	1288298.rosmuc_02246	5.326e-138	439.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria,46NSE@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CMS1_k127_4303050_0	1333998.M2A_2271	2.049e-114	374.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,4BPXQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ATPases associated with a variety of cellular activities	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_4303050_1	1280954.HPO_10542	3.184e-69	248.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,43WKC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
CMS1_k127_4303050_2	290397.Adeh_2242	6.282e-14	75.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,42U9X@68525|delta/epsilon subdivisions,2WQN5@28221|Deltaproteobacteria,2YXWV@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4315327_4	1305735.JAFT01000005_gene423	3.534e-138	439.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2PD7N@252301|Oceanicola	28211|Alphaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_4315327_6	1121479.AUBS01000007_gene2226	7.528e-88	298.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
CMS1_k127_4315327_5	391626.OAN307_c32000	4.543e-99	328.0	COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2U11D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS1_k127_4315327_1	1288298.rosmuc_02825	8.139e-175	550.0	COG1539@1|root,COG1539@2|Bacteria,1MY5Q@1224|Proteobacteria,2TRVX@28211|Alphaproteobacteria,46PRD@74030|Roseovarius	28211|Alphaproteobacteria	H	Dihydroneopterin aldolase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	4HFCP_synth,FolB
CMS1_k127_4315327_2	391613.RTM1035_04525	8.11e-162	516.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,46P56@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS1_k127_4315327_3	351016.RAZWK3B_18738	3.007e-150	480.0	COG0697@1|root,COG0697@2|Bacteria,1R3W3@1224|Proteobacteria,2TS0I@28211|Alphaproteobacteria,2P1K9@2433|Roseobacter	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4315327_0	266809.PM03_05210	1.266e-183	575.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_4326055_9	1354722.JQLS01000008_gene385	4.961e-26	107.0	COG3239@1|root,COG3239@2|Bacteria,1MXA8@1224|Proteobacteria,2TUQG@28211|Alphaproteobacteria,46QCS@74030|Roseovarius	28211|Alphaproteobacteria	I	COG3239 Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS1_k127_4326055_0	314264.ROS217_13881	1.237e-146	469.0	COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,2TUAQ@28211|Alphaproteobacteria,46N9T@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_39710	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4326055_2	1353537.TP2_07990	1.333e-86	292.0	COG0494@1|root,COG0494@2|Bacteria,1N8EV@1224|Proteobacteria,2TTNV@28211|Alphaproteobacteria,2XMXD@285107|Thioclava	28211|Alphaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	MA20_36340	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_4326055_6	351016.RAZWK3B_20016	3.357e-64	224.0	COG5349@1|root,COG5349@2|Bacteria,1MZDD@1224|Proteobacteria,2UCM4@28211|Alphaproteobacteria,2P35H@2433|Roseobacter	28211|Alphaproteobacteria	S	COG1405 Transcription initiation factor TFIIIB, Brf1 subunit Transcription initiation factor TFIIB	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS1_k127_4326055_8	351016.RAZWK3B_20011	1.033e-44	169.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2UF3D@28211|Alphaproteobacteria,2P3T0@2433|Roseobacter	28211|Alphaproteobacteria	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5
CMS1_k127_4326055_4	314264.ROS217_13861	1.917e-84	283.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,46PN7@74030|Roseovarius	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4326055_10	314271.RB2654_21073	1.68e-11	69.0	2EJ16@1|root,33CSD@2|Bacteria,1NGGV@1224|Proteobacteria,2UJAI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4326055_7	1354722.JQLS01000008_gene378	3.298e-50	184.0	2E4Q0@1|root,32ZIM@2|Bacteria,1N6SU@1224|Proteobacteria,2UFRW@28211|Alphaproteobacteria,46PBC@74030|Roseovarius	28211|Alphaproteobacteria	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
CMS1_k127_4326055_3	1288298.rosmuc_02443	5.369e-85	284.0	28NIR@1|root,2ZBK2@2|Bacteria,1RAAF@1224|Proteobacteria,2U5XR@28211|Alphaproteobacteria,46Q0N@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4326055_1	1354722.JQLS01000008_gene390	6.141e-122	394.0	COG0340@1|root,COG0340@2|Bacteria,1N1WU@1224|Proteobacteria,2TQK4@28211|Alphaproteobacteria,46Q6G@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0340 Biotin-(acetyl-CoA carboxylase) ligase	-	-	-	-	-	-	-	-	-	-	-	-	BPL_LplA_LipB_2,DUF4444
CMS1_k127_4326055_5	1288298.rosmuc_02445	4.731e-83	276.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,46PM1@74030|Roseovarius	28211|Alphaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS1_k127_4335810_9	1123501.KB902315_gene3436	5.881e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_4335810_2	1305735.JAFT01000005_gene2185	2.059e-115	377.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2TV0U@28211|Alphaproteobacteria,2PF9E@252301|Oceanicola	28211|Alphaproteobacteria	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N
CMS1_k127_4335810_0	391613.RTM1035_06333	3.838e-228	711.0	COG1804@1|root,COG1804@2|Bacteria,1R43P@1224|Proteobacteria,2U1WN@28211|Alphaproteobacteria,46NAB@74030|Roseovarius	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	5.4.1.3	ko:K14470	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09283	RC02480	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS1_k127_4335810_7	314264.ROS217_16630	3.579e-28	122.0	29ET5@1|root,301QX@2|Bacteria,1PTQD@1224|Proteobacteria,2V5JG@28211|Alphaproteobacteria,46QSS@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4335810_6	314264.ROS217_16635	2.819e-31	123.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,46R79@74030|Roseovarius	28211|Alphaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS1_k127_4335810_3	314264.ROS217_16640	8.145e-104	339.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2TRID@28211|Alphaproteobacteria,46P9G@74030|Roseovarius	28211|Alphaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_4335810_5	1354722.JQLS01000008_gene681	2.395e-78	264.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2U760@28211|Alphaproteobacteria,46QTF@74030|Roseovarius	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS1_k127_4335810_1	1288298.rosmuc_01076	2.55e-129	415.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2TRXP@28211|Alphaproteobacteria,46PD9@74030|Roseovarius	28211|Alphaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_4335810_4	644076.SCH4B_1012	7.958e-88	294.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2U592@28211|Alphaproteobacteria,4NA25@97050|Ruegeria	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS1_k127_4335810_8	1415756.JQMY01000001_gene1133	1.5e-22	98.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,2PE1T@252301|Oceanicola	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS1_k127_4341155_4	1354722.JQLS01000008_gene2952	6.615e-72	246.0	COG3793@1|root,COG3793@2|Bacteria,1RD1X@1224|Proteobacteria,2U788@28211|Alphaproteobacteria,46QND@74030|Roseovarius	28211|Alphaproteobacteria	P	PFAM Mo-dependent nitrogenase	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS1_k127_4341155_0	1354722.JQLS01000008_gene2951	0.0	1000.0	COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,46QE6@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
CMS1_k127_4341155_5	314264.ROS217_11716	2.467e-58	205.0	COG2010@1|root,COG2010@2|Bacteria,1N7M9@1224|Proteobacteria,2UFTS@28211|Alphaproteobacteria,46QVY@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_4341155_2	1123247.AUIJ01000017_gene2739	2.163e-149	476.0	COG1177@1|root,COG1177@2|Bacteria,1MWVC@1224|Proteobacteria,2TV8E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG1177 ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_4341155_1	571166.KI421509_gene2493	2.354e-153	489.0	COG1176@1|root,COG1176@2|Bacteria,1MW9Y@1224|Proteobacteria,2TTFC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG1176 ABC-type spermidine putrescine transport system permease component I	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_4341155_3	1123247.AUIJ01000017_gene2737	8.202e-130	418.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS1_k127_434742_5	1354722.JQLS01000008_gene1483	3.104e-61	213.0	2BKYU@1|root,32FFG@2|Bacteria,1RHT5@1224|Proteobacteria,2UA28@28211|Alphaproteobacteria,46QPJ@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS1_k127_434742_1	1354722.JQLS01000008_gene1484	3.984e-232	723.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,46Q2T@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_434742_3	314264.ROS217_20517	8.265e-148	469.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,46NHE@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS1_k127_434742_4	351016.RAZWK3B_16075	6.06e-95	314.0	COG3914@1|root,COG3914@2|Bacteria,1RE54@1224|Proteobacteria,2U5XB@28211|Alphaproteobacteria,2P4YJ@2433|Roseobacter	28211|Alphaproteobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_434742_0	314264.ROS217_20532	0.0	1000.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,46NCI@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_434742_2	1288298.rosmuc_01551	1.694e-175	558.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,46NAT@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	nifS	GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS1_k127_434742_6	1354722.JQLS01000007_gene3816	6.205e-18	83.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	iscR	GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.8.1.7	ko:K04487,ko:K13643	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03000,ko03016,ko03029	-	-	-	Rrf2
CMS1_k127_436025_2	391613.RTM1035_08719	1.63e-162	513.0	COG0747@1|root,COG0747@2|Bacteria,1MXQ4@1224|Proteobacteria,2TTIZ@28211|Alphaproteobacteria,46PIU@74030|Roseovarius	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_436025_3	1354722.JQLS01000008_gene1551	3.139e-100	329.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2U5GT@28211|Alphaproteobacteria,46Q2G@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_436025_5	1288298.rosmuc_01491	4.269e-87	289.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,46PCT@74030|Roseovarius	28211|Alphaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS1_k127_436025_4	1354722.JQLS01000008_gene1553	2.23e-99	333.0	COG2348@1|root,COG2348@2|Bacteria,1N1ZZ@1224|Proteobacteria,2UCZJ@28211|Alphaproteobacteria,46PK9@74030|Roseovarius	28211|Alphaproteobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
CMS1_k127_436025_1	1288298.rosmuc_01489	0.0	1120.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,46P8T@74030|Roseovarius	28211|Alphaproteobacteria	T	membrane GTPase involved in stress response	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_436025_6	1354722.JQLS01000008_gene1555	4.825e-51	181.0	COG5470@1|root,COG5470@2|Bacteria,1RGYN@1224|Proteobacteria,2U9AN@28211|Alphaproteobacteria,46R06@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_436025_7	1288298.rosmuc_01486	2.264e-42	159.0	COG5470@1|root,COG5470@2|Bacteria,1N1D1@1224|Proteobacteria,2UD77@28211|Alphaproteobacteria,46R1R@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_436025_0	1354722.JQLS01000008_gene1557	0.0	1569.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,46Q8W@74030|Roseovarius	28211|Alphaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_4360322_6	391593.RCCS2_05484	5.003e-18	83.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,2TTA9@28211|Alphaproteobacteria,2P282@2433|Roseobacter	28211|Alphaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4360322_7	314271.RB2654_21318	0.0008835	45.0	COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2TU2T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ICC-like phosphoesterases	MA20_22045	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
CMS1_k127_4360322_3	391613.RTM1035_15307	6.673e-89	300.0	COG3279@1|root,COG3279@2|Bacteria,1N903@1224|Proteobacteria,2UCXI@28211|Alphaproteobacteria,46NKW@74030|Roseovarius	28211|Alphaproteobacteria	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
CMS1_k127_4360322_5	351016.RAZWK3B_06727	5.952e-64	221.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria,2P3C6@2433|Roseobacter	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_4360322_0	314264.ROS217_05814	3.426e-256	799.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,46PCW@74030|Roseovarius	28211|Alphaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_4360322_2	314264.ROS217_05809	8.608e-107	351.0	COG0705@1|root,COG0705@2|Bacteria,1RA4A@1224|Proteobacteria,2U5JY@28211|Alphaproteobacteria,46PDK@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_4360322_1	1354722.JQLS01000008_gene249	2.896e-202	631.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria,46ND5@74030|Roseovarius	28211|Alphaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS1_k127_4360322_4	1354722.JQLS01000008_gene250	6.026e-85	287.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,46QAH@74030|Roseovarius	28211|Alphaproteobacteria	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
CMS1_k127_4367813_0	1354722.JQLS01000008_gene3042	3.419e-115	382.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,46PAP@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_4367813_1	314264.ROS217_11261	1.298e-97	319.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2TTCK@28211|Alphaproteobacteria,46P1F@74030|Roseovarius	28211|Alphaproteobacteria	K	Proline dehydrogenase transcriptional activator	lrp	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_4367813_2	1354722.JQLS01000008_gene3044	3.34e-96	321.0	COG2931@1|root,COG2931@2|Bacteria,1R6W7@1224|Proteobacteria,2U1XK@28211|Alphaproteobacteria,46NE7@74030|Roseovarius	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_4388671_0	1288298.rosmuc_02123	1.145e-214	671.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2TS9C@28211|Alphaproteobacteria,46QFU@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1448 Aspartate tyrosine aromatic aminotransferase	tyrB	-	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_4388671_2	391613.RTM1035_01690	1.093e-169	534.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,46Q4G@74030|Roseovarius	28211|Alphaproteobacteria	P	COG2897 Rhodanese-related sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_4388671_7	1165096.ARWF01000001_gene1146	2.634e-22	99.0	2E5PA@1|root,330E0@2|Bacteria,1PJRE@1224|Proteobacteria,2W851@28216|Betaproteobacteria,2KNYY@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4388671_5	89187.ISM_08770	1.11e-83	279.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,46NHN@74030|Roseovarius	28211|Alphaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS1_k127_4388671_4	1354722.JQLS01000008_gene2873	7.269e-110	358.0	COG1802@1|root,COG1802@2|Bacteria,1RBIC@1224|Proteobacteria,2U60T@28211|Alphaproteobacteria,46PDB@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1802 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_4388671_1	1354722.JQLS01000008_gene2872	5.092e-180	568.0	COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,2TV91@28211|Alphaproteobacteria,46QH4@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	MA20_30160	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_4388671_6	351016.RAZWK3B_11061	3.443e-77	263.0	COG3090@1|root,COG3090@2|Bacteria,1MVKS@1224|Proteobacteria,2U08K@28211|Alphaproteobacteria,2P22J@2433|Roseobacter	28211|Alphaproteobacteria	G	transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_4388671_3	1342302.JASC01000014_gene1158	1.521e-141	452.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,3ZVHX@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	MA20_30170	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_442374_1	1250005.PHEL85_0405	3.399e-31	127.0	COG0599@1|root,COG0599@2|Bacteria,4NYAJ@976|Bacteroidetes,1I9PN@117743|Flavobacteriia,3VXC4@52959|Polaribacter	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_442374_0	926569.ANT_05380	1.507e-145	470.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
CMS1_k127_4436028_2	1123360.thalar_01173	2.336e-16	79.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	MA20_40290	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_4436028_1	1354722.JQLS01000005_gene3925	4.599e-187	587.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,46RFS@74030|Roseovarius	28211|Alphaproteobacteria	S	NMT1-like family	imp	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_4436028_0	1354722.JQLS01000005_gene3924	0.0	1261.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,46RQW@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
CMS1_k127_4438855_3	314264.ROS217_09742	1.324e-35	143.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,46PK0@74030|Roseovarius	28211|Alphaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS1_k127_4438855_1	391613.RTM1035_18490	9.965e-203	633.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria,46P4I@74030|Roseovarius	28211|Alphaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CMS1_k127_4438855_2	391613.RTM1035_18485	7.804e-97	318.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria,46NC9@74030|Roseovarius	28211|Alphaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_4438855_0	1354722.JQLS01000008_gene3496	0.0	1038.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,46PGN@74030|Roseovarius	28211|Alphaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_4441235_0	351016.RAZWK3B_13479	4.027e-123	402.0	COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria,2U17B@28211|Alphaproteobacteria,2P3YY@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0591 Na proline symporter	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_4441235_1	83219.PM02_01275	8.835e-122	394.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,3ZW49@60136|Sulfitobacter	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_19195	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_4441235_2	744980.TRICHSKD4_2783	3.36e-38	158.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U0C2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_44421_2	1569209.BBPH01000025_gene211	2.09e-34	132.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2TR5R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS1_k127_44421_1	351016.RAZWK3B_16330	3.988e-119	386.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,2P2ER@2433|Roseobacter	28211|Alphaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS1_k127_44421_0	1288298.rosmuc_01452	4.052e-143	455.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2TS1V@28211|Alphaproteobacteria,46PFN@74030|Roseovarius	28211|Alphaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS1_k127_4449253_4	1288298.rosmuc_01597	3.564e-84	284.0	COG2197@1|root,COG2197@2|Bacteria,1NH4V@1224|Proteobacteria,2TT7J@28211|Alphaproteobacteria,46NVA@74030|Roseovarius	28211|Alphaproteobacteria	K	Autoinducer-binding transcriptional regulator, LuxR family protein	luxR	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Autoind_bind,GerE
CMS1_k127_4449253_5	391613.RTM1035_08214	7.659e-70	239.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,46QSE@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS1_k127_4449253_1	1288298.rosmuc_01600	3.939e-213	670.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2TS4Z@28211|Alphaproteobacteria,46PGU@74030|Roseovarius	28211|Alphaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_4449253_3	1354722.JQLS01000008_gene1386	1.57e-192	611.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,46NMG@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	ordL	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_4449253_0	1305735.JAFT01000005_gene3346	0.0	1041.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1P31Y@1224|Proteobacteria,2TQTU@28211|Alphaproteobacteria,2PF3Y@252301|Oceanicola	28211|Alphaproteobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS1_k127_4449253_2	1288298.rosmuc_01602	5.439e-201	626.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,46Q0W@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_446184_7	1122614.JHZF01000013_gene3429	1.294e-141	453.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2TT7B@28211|Alphaproteobacteria,2PDFP@252301|Oceanicola	28211|Alphaproteobacteria	P	Inositol monophosphatase family	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS1_k127_446184_6	1354722.JQLS01000008_gene3236	3.784e-142	454.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,46PBF@74030|Roseovarius	28211|Alphaproteobacteria	M	COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS1_k127_446184_4	1288298.rosmuc_00082	1.713e-179	563.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,46PBM@74030|Roseovarius	28211|Alphaproteobacteria	M	UDP-glucose pyrophosphorylase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_446184_3	314264.ROS217_10927	1.047e-194	609.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,46P81@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_446184_5	391613.RTM1035_17935	3.661e-179	568.0	COG0463@1|root,COG0463@2|Bacteria,1MWA0@1224|Proteobacteria,2TTR5@28211|Alphaproteobacteria,46QCH@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
CMS1_k127_446184_9	1288298.rosmuc_00085	2.595e-109	357.0	COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,2TUK3@28211|Alphaproteobacteria,46NDG@74030|Roseovarius	28211|Alphaproteobacteria	S	hydrolases of HD superfamily	MA20_42120	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	HD,HD_3
CMS1_k127_446184_8	314264.ROS217_10912	3.673e-133	431.0	COG2242@1|root,COG2242@2|Bacteria,1R3Z5@1224|Proteobacteria,2TT0M@28211|Alphaproteobacteria,46PWN@74030|Roseovarius	28211|Alphaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_446184_17	1354722.JQLS01000008_gene3230	5.799e-41	153.0	2EMKN@1|root,33F92@2|Bacteria,1NHNJ@1224|Proteobacteria,2UJWA@28211|Alphaproteobacteria,46RCB@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_446184_0	1288298.rosmuc_00088	3.474e-283	872.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,46PC3@74030|Roseovarius	28211|Alphaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS1_k127_446184_14	246200.SPO3859	4.107e-61	213.0	2ADBR@1|root,31316@2|Bacteria,1RD6U@1224|Proteobacteria,2U75P@28211|Alphaproteobacteria,4NCB5@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2853
CMS1_k127_446184_11	314264.ROS217_10887	4.792e-89	296.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,2U7ND@28211|Alphaproteobacteria,46Q3Q@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_446184_10	1288298.rosmuc_00092	1.614e-100	329.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,2U5W7@28211|Alphaproteobacteria,46NDA@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_446184_2	1354722.JQLS01000008_gene3225	4.97e-241	750.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TR8I@28211|Alphaproteobacteria,46NUA@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_446184_13	1288298.rosmuc_00094	6.144e-76	255.0	COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,2U994@28211|Alphaproteobacteria,46QPX@74030|Roseovarius	28211|Alphaproteobacteria	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
CMS1_k127_446184_1	391613.RTM1035_17985	3.757e-268	832.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,2TQQF@28211|Alphaproteobacteria,46Q13@74030|Roseovarius	28211|Alphaproteobacteria	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
CMS1_k127_446184_12	1354722.JQLS01000008_gene3222	3.394e-82	273.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,46QRY@74030|Roseovarius	28211|Alphaproteobacteria	S	EVE domain	MA20_25125	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS1_k127_446184_16	1354722.JQLS01000008_gene3221	5.43e-45	164.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2UF4X@28211|Alphaproteobacteria,46R2D@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	yciI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
CMS1_k127_446184_15	1288298.rosmuc_00146	2.147e-46	168.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,46P09@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0240 Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS1_k127_4468367_2	314264.ROS217_15305	1.039e-72	248.0	COG2931@1|root,COG2931@2|Bacteria,1R6NH@1224|Proteobacteria,2U10I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_4468367_0	1354722.JQLS01000008_gene2231	1.425e-216	675.0	COG0075@1|root,COG0075@2|Bacteria,1QM2D@1224|Proteobacteria,2TSQ5@28211|Alphaproteobacteria,46PVA@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_4468367_1	391613.RTM1035_04555	2.24e-129	415.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TT9M@28211|Alphaproteobacteria,46PJV@74030|Roseovarius	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS1_k127_4477887_0	351016.RAZWK3B_11536	0.0	1551.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,2P1HF@2433|Roseobacter	28211|Alphaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_4477887_4	314264.ROS217_15530	3.042e-153	491.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,2U20B@28211|Alphaproteobacteria,46P9P@74030|Roseovarius	28211|Alphaproteobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
CMS1_k127_4477887_8	391613.RTM1035_13123	4.074e-69	237.0	COG1522@1|root,COG1522@2|Bacteria,1RH53@1224|Proteobacteria,2U9NS@28211|Alphaproteobacteria,46QU0@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS1_k127_4477887_2	1354722.JQLS01000008_gene2150	4.293e-194	616.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,46Q9F@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family	ldc	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_4477887_1	351016.RAZWK3B_11551	0.0	1244.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2P2E6@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_4477887_5	246200.SPO3018	2.883e-148	477.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,2TQTY@28211|Alphaproteobacteria,4NA0A@97050|Ruegeria	28211|Alphaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
CMS1_k127_4477887_7	1354722.JQLS01000008_gene2144	5.028e-73	252.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2U9U1@28211|Alphaproteobacteria,46QSB@74030|Roseovarius	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_4477887_3	1354722.JQLS01000008_gene2143	1.615e-176	555.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria,46PW5@74030|Roseovarius	28211|Alphaproteobacteria	E	5,10-methylenetetrahydrofolate reductase	metF	GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_4477887_6	1288298.rosmuc_01991	2.339e-124	398.0	COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,2TT9N@28211|Alphaproteobacteria,46PCE@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0583 Transcriptional regulator	metR	-	-	ko:K03576	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4521735_3	391613.RTM1035_08209	5.635e-74	255.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2TS4Z@28211|Alphaproteobacteria,46PGU@74030|Roseovarius	28211|Alphaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_4521735_4	375451.RD1_0225	2.18e-65	229.0	COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria,2P40J@2433|Roseobacter	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_4521735_6	1288298.rosmuc_03629	1.452e-46	169.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2U401@28211|Alphaproteobacteria,46RY3@74030|Roseovarius	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
CMS1_k127_4521735_8	1288298.rosmuc_03629	9.622e-07	53.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2U401@28211|Alphaproteobacteria,46RY3@74030|Roseovarius	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
CMS1_k127_4521735_2	570967.JMLV01000013_gene3429	3.476e-79	272.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,2JTC3@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_4521735_7	1380380.JIAX01000002_gene2849	3.789e-07	51.0	COG1484@1|root,COG1484@2|Bacteria,1NP5E@1224|Proteobacteria,2UYQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA-dependent DNA replication	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4521735_0	1354722.JQLS01000008_gene66	0.0	1373.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,46NU0@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdZ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_4521735_5	391613.RTM1035_16077	7.467e-65	248.0	COG5458@1|root,COG5458@2|Bacteria,1N054@1224|Proteobacteria,2UBY1@28211|Alphaproteobacteria,46QRK@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1489)	MA20_36070	-	-	-	-	-	-	-	-	-	-	-	DUF1489
CMS1_k127_4521735_1	1354722.JQLS01000008_gene68	8.21e-86	288.0	COG3637@1|root,COG3637@2|Bacteria,1R4WV@1224|Proteobacteria,2U0V2@28211|Alphaproteobacteria,46RJ8@74030|Roseovarius	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	MA20_19585	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
CMS1_k127_4521886_13	1354722.JQLS01000008_gene2346	1.839e-29	121.0	COG3709@1|root,COG3709@2|Bacteria,1RK3Z@1224|Proteobacteria,2U616@28211|Alphaproteobacteria,46Q2C@74030|Roseovarius	28211|Alphaproteobacteria	P	Protein of unknown function (DUF1045)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1045
CMS1_k127_4521886_9	314264.ROS217_04290	1.073e-111	366.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2TRTM@28211|Alphaproteobacteria,46P2J@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	nagK	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
CMS1_k127_4521886_6	1354722.JQLS01000008_gene2349	4.106e-150	481.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,2U072@28211|Alphaproteobacteria,46N99@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1275 Tellurite resistance protein and related permeases	tehA	-	-	ko:K03304	-	-	-	-	ko00000,ko02000	2.A.16.1	-	-	SLAC1
CMS1_k127_4521886_2	1288298.rosmuc_01783	8.524e-320	984.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR78@28211|Alphaproteobacteria,46P5V@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	mcd	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4521886_8	314264.ROS217_04380	8.465e-129	415.0	COG0730@1|root,COG0730@2|Bacteria,1MWAN@1224|Proteobacteria,2TS4X@28211|Alphaproteobacteria,46QC9@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_4521886_1	351016.RAZWK3B_09366	0.0	1017.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,2P188@2433|Roseobacter	28211|Alphaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS1_k127_4521886_7	1288298.rosmuc_02553	5.921e-137	438.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,46Q7R@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	chvI	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K14981	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4521886_3	314264.ROS217_04085	6.025e-298	921.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,2TWBW@28211|Alphaproteobacteria,46NE2@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	chvG	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Sensor_TM1
CMS1_k127_4521886_11	391613.RTM1035_03845	6.022e-54	194.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2UFPB@28211|Alphaproteobacteria,46QXE@74030|Roseovarius	28211|Alphaproteobacteria	T	COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C
CMS1_k127_4521886_5	1354722.JQLS01000008_gene485	3.342e-152	485.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2TTI4@28211|Alphaproteobacteria,46NYV@74030|Roseovarius	28211|Alphaproteobacteria	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS1_k127_4521886_10	391613.RTM1035_03855	4.033e-67	231.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,46QNA@74030|Roseovarius	28211|Alphaproteobacteria	G	COG2893 Phosphotransferase system, mannose fructose-specific component IIA	manX	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
CMS1_k127_4521886_12	314264.ROS217_04065	4.032e-41	153.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,46R0D@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS1_k127_4521886_4	314264.ROS217_04060	2.357e-169	537.0	COG0204@1|root,COG0204@2|Bacteria,1QU3F@1224|Proteobacteria,2TSPD@28211|Alphaproteobacteria,46NK2@74030|Roseovarius	28211|Alphaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS1_k127_4521886_0	1354722.JQLS01000008_gene497	0.0	1163.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,46PW4@74030|Roseovarius	28211|Alphaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_4552721_11	1354722.JQLS01000008_gene756	3.135e-08	55.0	2BV99@1|root,32QP2@2|Bacteria,1Q4RN@1224|Proteobacteria,2VB6T@28211|Alphaproteobacteria,46R4F@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4552721_10	314264.ROS217_17015	1.83e-13	77.0	2AEEA@1|root,31493@2|Bacteria,1PTRU@1224|Proteobacteria,2VB8R@28211|Alphaproteobacteria,46R8F@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4552721_2	314264.ROS217_17020	1.765e-210	657.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2TUES@28211|Alphaproteobacteria,46NCX@74030|Roseovarius	28211|Alphaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
CMS1_k127_4552721_1	1354722.JQLS01000008_gene753	2.949e-214	670.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,46QF3@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_4552721_5	1415756.JQMY01000001_gene1510	3.206e-128	412.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,2PFE2@252301|Oceanicola	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS1_k127_4552721_7	314264.ROS217_17005	1.787e-109	357.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria,46P0P@74030|Roseovarius	28211|Alphaproteobacteria	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
CMS1_k127_4552721_4	391613.RTM1035_05715	2.037e-165	523.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria,46QDR@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
CMS1_k127_4552721_3	1354722.JQLS01000008_gene746	3.01e-188	595.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,46P63@74030|Roseovarius	28211|Alphaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS1_k127_4552721_0	351016.RAZWK3B_20571	0.0	1038.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,2P1IV@2433|Roseobacter	28211|Alphaproteobacteria	C	Formate dehydrogenase, beta subunit	nuoEF	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_4552721_6	1354722.JQLS01000008_gene744	4.108e-126	411.0	COG3239@1|root,COG3239@2|Bacteria,1N42R@1224|Proteobacteria,2U06U@28211|Alphaproteobacteria,46NIS@74030|Roseovarius	28211|Alphaproteobacteria	C	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
CMS1_k127_4552864_3	314264.ROS217_03935	1.896e-84	282.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6B7@28211|Alphaproteobacteria,46PX5@74030|Roseovarius	28211|Alphaproteobacteria	S	UPF0126 domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0126
CMS1_k127_4552864_2	1423144.Gal_00227	5.586e-89	295.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,34EDE@302485|Phaeobacter	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS1_k127_4552864_4	314264.ROS217_03925	5.562e-76	257.0	2A57D@1|root,2ZYPI@2|Bacteria,1RDQ9@1224|Proteobacteria,2U7GJ@28211|Alphaproteobacteria,46QRQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3429
CMS1_k127_4552864_1	351016.RAZWK3B_09151	1.731e-89	303.0	2F9ZR@1|root,3428V@2|Bacteria,1NY5S@1224|Proteobacteria,2USXM@28211|Alphaproteobacteria,2P2ZR@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4552864_0	391613.RTM1035_14367	2.755e-121	391.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,46NRG@74030|Roseovarius	28211|Alphaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CMS1_k127_4556838_14	314264.ROS217_11276	3.356e-19	87.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,46PEG@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system	tauB	GO:0003674,GO:0003824,GO:0005215,GO:0005342,GO:0005368,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0008559,GO:0015075,GO:0015238,GO:0015399,GO:0015405,GO:0015411,GO:0015711,GO:0015734,GO:0015849,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033283,GO:0034220,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042908,GO:0042910,GO:0043492,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:0098656,GO:1901682,GO:1903825	3.6.3.36	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
CMS1_k127_4556838_2	314264.ROS217_11281	2.981e-194	608.0	COG4521@1|root,COG4521@2|Bacteria,1MVH2@1224|Proteobacteria,2TVXB@28211|Alphaproteobacteria,46PQF@74030|Roseovarius	28211|Alphaproteobacteria	P	COG4521 ABC-type taurine transport system, periplasmic component	tauA	-	-	ko:K15551	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	NMT1
CMS1_k127_4556838_0	1288298.rosmuc_00827	4.512e-294	906.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TR8R@28211|Alphaproteobacteria,46Q8Y@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	tpa	-	2.6.1.77	ko:K03851	ko00430,ko01100,map00430,map01100	-	R05652	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_4556838_10	391613.RTM1035_03935	8.296e-60	214.0	COG1280@1|root,COG1280@2|Bacteria,1PP0Q@1224|Proteobacteria,2V823@28211|Alphaproteobacteria,46RW6@74030|Roseovarius	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_4556838_6	314264.ROS217_12586	6.519e-138	441.0	COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,46QAU@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_20925	-	-	ko:K09987	-	-	-	-	ko00000	-	-	-	DUF1013
CMS1_k127_4556838_9	351016.RAZWK3B_05977	1.845e-107	351.0	COG3719@1|root,COG3719@2|Bacteria,1PTUN@1224|Proteobacteria,2TQUU@28211|Alphaproteobacteria,2P1FX@2433|Roseobacter	28211|Alphaproteobacteria	J	Belongs to the RNase T2 family	rns	-	3.1.27.1,3.1.27.6	ko:K01166,ko:K01169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_T2
CMS1_k127_4556838_4	1354722.JQLS01000008_gene3020	1.822e-157	504.0	COG4692@1|root,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2V3Y3@28211|Alphaproteobacteria,46RH4@74030|Roseovarius	28211|Alphaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_4556838_3	314264.ROS217_11426	7.576e-181	569.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,46P9S@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	ppsC	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4556838_8	1288298.rosmuc_00798	5.305e-115	374.0	COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria,46PSQ@74030|Roseovarius	28211|Alphaproteobacteria	S	COQ9	cOQ9	-	-	ko:K18587	-	-	-	-	ko00000	-	-	-	COQ9
CMS1_k127_4556838_12	1354722.JQLS01000008_gene3017	1.374e-29	120.0	2EN51@1|root,33FT2@2|Bacteria,1NGN8@1224|Proteobacteria,2UK3V@28211|Alphaproteobacteria,46S1W@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4556838_13	1288298.rosmuc_00800	4.698e-21	97.0	2EJ3U@1|root,33CV3@2|Bacteria,1NI6Q@1224|Proteobacteria,2UN1W@28211|Alphaproteobacteria,46R6E@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4556838_7	1354722.JQLS01000008_gene3015	2.786e-124	402.0	COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,2U18K@28211|Alphaproteobacteria,46PRG@74030|Roseovarius	28211|Alphaproteobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS1_k127_4556838_5	1354722.JQLS01000008_gene3014	9.228e-155	493.0	28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,2U3BP@28211|Alphaproteobacteria,46P3E@74030|Roseovarius	28211|Alphaproteobacteria	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
CMS1_k127_4556838_1	375451.RD1_0192	4.069e-195	610.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria,2P1P0@2433|Roseobacter	28211|Alphaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_4597229_4	1123501.KB902313_gene2915	0.0005102	43.0	COG0438@1|root,COG0438@2|Bacteria,1RJ6C@1224|Proteobacteria,2U50C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_4597229_2	1354722.JQLS01000008_gene2536	3.606e-90	303.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2U7DN@28211|Alphaproteobacteria,46Q78@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	rfbP	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CMS1_k127_4597229_0	1380367.JIBC01000005_gene3448	6.259e-183	574.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,3ZUVN@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_4597229_3	314264.ROS217_14091	1.601e-89	297.0	COG1846@1|root,COG1846@2|Bacteria,1RIX7@1224|Proteobacteria,2U94M@28211|Alphaproteobacteria,46NN8@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1846 Transcriptional regulators	petP	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_4597229_1	1354722.JQLS01000008_gene2539	6.263e-102	332.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,46Q3N@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	petR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4615941_0	314264.ROS217_17122	2.665e-230	726.0	COG4655@1|root,COG4655@2|Bacteria,1QVW2@1224|Proteobacteria,2TWKN@28211|Alphaproteobacteria,46PX0@74030|Roseovarius	28211|Alphaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	Tad,VWA
CMS1_k127_4615941_3	314264.ROS217_17117	1.732e-67	234.0	COG4961@1|root,COG4961@2|Bacteria,1MZBW@1224|Proteobacteria,2UCBG@28211|Alphaproteobacteria,46P2T@74030|Roseovarius	28211|Alphaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS1_k127_4615941_2	1354722.JQLS01000008_gene848	9.581e-71	245.0	COG4961@1|root,COG4961@2|Bacteria,1N0BF@1224|Proteobacteria,2UCIU@28211|Alphaproteobacteria,46PKW@74030|Roseovarius	28211|Alphaproteobacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS1_k127_4615941_4	1354722.JQLS01000008_gene847	1.717e-54	195.0	2CDK9@1|root,32RXY@2|Bacteria,1MZP4@1224|Proteobacteria,2UCWW@28211|Alphaproteobacteria,46QAG@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4615941_1	351016.RAZWK3B_19886	3.742e-178	561.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2P12X@2433|Roseobacter	28211|Alphaproteobacteria	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS1_k127_4615941_5	89187.ISM_12930	3.608e-13	69.0	COG1309@1|root,COG1309@2|Bacteria,1R7JI@1224|Proteobacteria,2U0P5@28211|Alphaproteobacteria,46NQC@74030|Roseovarius	28211|Alphaproteobacteria	K	transcriptional regulator, TetR family	kstR2	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
CMS1_k127_4619706_1	391613.RTM1035_06383	1.597e-255	789.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,46P7F@74030|Roseovarius	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_4619706_0	391613.RTM1035_06378	0.0	1763.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,46NBY@74030|Roseovarius	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS1_k127_4626557_1	83219.PM02_00040	3.248e-204	636.0	COG4927@1|root,COG4927@2|Bacteria,1MY0W@1224|Proteobacteria,2TTM1@28211|Alphaproteobacteria,3ZWSN@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS1_k127_4626557_0	1354722.JQLS01000005_gene3919	6.633e-266	821.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,46NHC@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_4626557_2	391593.RCCS2_12649	5.372e-84	280.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2TQMU@28211|Alphaproteobacteria,2P2C6@2433|Roseobacter	28211|Alphaproteobacteria	H	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
CMS1_k127_4644759_1	1123360.thalar_00553	4.015e-127	417.0	COG4948@1|root,COG4948@2|Bacteria,1MW3F@1224|Proteobacteria,2U1H9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate racemase muconate lactonizing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4644759_0	351016.RAZWK3B_17248	7.296e-143	458.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria,2P1UZ@2433|Roseobacter	28211|Alphaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	dehH	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_4644759_2	314264.ROS217_21742	7.783e-108	350.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TQY4@28211|Alphaproteobacteria,46NZM@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	dapE_1	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_4648190_1	1354722.JQLS01000008_gene1613	9.54e-102	336.0	COG4233@1|root,COG4233@2|Bacteria,1REVE@1224|Proteobacteria,2VEXK@28211|Alphaproteobacteria,46QFN@74030|Roseovarius	28211|Alphaproteobacteria	CO	to be involved in C-type cytochrome biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CMS1_k127_4648190_2	1354722.JQLS01000008_gene1614	2.988e-91	303.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2TTX4@28211|Alphaproteobacteria,46PVH@74030|Roseovarius	28211|Alphaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	MA20_18155	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS1_k127_4648190_0	1354722.JQLS01000008_gene1615	8.538e-243	759.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,46PQ1@74030|Roseovarius	28211|Alphaproteobacteria	T	COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system	dctB	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
CMS1_k127_46630_2	351016.RAZWK3B_15023	2.611e-112	369.0	COG0583@1|root,COG0583@2|Bacteria,1RCQR@1224|Proteobacteria,2TV2A@28211|Alphaproteobacteria,2P35P@2433|Roseobacter	28211|Alphaproteobacteria	K	Transcriptional Regulator, LysR family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_46630_4	314264.ROS217_22277	1.847e-62	217.0	COG3474@1|root,COG3474@2|Bacteria,1N0S1@1224|Proteobacteria,2UC0E@28211|Alphaproteobacteria,46QRP@74030|Roseovarius	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_46630_5	314264.ROS217_22182	3.82e-13	72.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria,46Q7E@74030|Roseovarius	28211|Alphaproteobacteria	C	geranylgeranyl reductase	bchP	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2
CMS1_k127_46630_3	391613.RTM1035_12018	4.08e-90	300.0	COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,2U5P8@28211|Alphaproteobacteria,46NCJ@74030|Roseovarius	28211|Alphaproteobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
CMS1_k127_46630_1	351016.RAZWK3B_06532	3.889e-144	467.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRIH@28211|Alphaproteobacteria,2P1HQ@2433|Roseobacter	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	caiD	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
CMS1_k127_46630_0	351016.RAZWK3B_06527	1.334e-276	867.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2P290@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1042 Acyl-CoA synthetase (NDP forming)	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS1_k127_467305_2	1354722.JQLS01000008_gene2113	2.331e-64	220.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,46QRM@74030|Roseovarius	28211|Alphaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS1_k127_467305_0	391613.RTM1035_04870	0.0	1016.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,46Q6V@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_467305_3	1288298.rosmuc_02897	2.225e-50	183.0	2ER2E@1|root,33IN0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_467305_1	391613.RTM1035_04865	5.635e-86	287.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria,46PY9@74030|Roseovarius	28211|Alphaproteobacteria	U	COG2095 Multiple antibiotic transporter	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS1_k127_4675254_2	991905.SL003B_4017	1.024e-58	211.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,2UIDR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4675254_4	991905.SL003B_4016	4.335e-09	58.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,4BS2I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4675254_3	391626.OAN307_c18830	6.946e-18	84.0	COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
CMS1_k127_4675254_1	633131.TR2A62_0195	5.616e-75	256.0	COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
CMS1_k127_4675254_0	1123360.thalar_03471	1.272e-160	511.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4678735_4	1472418.BBJC01000001_gene339	1.371e-15	76.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_4678735_0	314264.ROS217_06965	9.426e-153	489.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG3000 Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_4678735_2	1354722.JQLS01000008_gene96	1.357e-140	448.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,46NM5@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_4678735_1	314264.ROS217_06975	5.108e-149	477.0	COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,46NCZ@74030|Roseovarius	28211|Alphaproteobacteria	D	COG2177 Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
CMS1_k127_4678735_3	351016.RAZWK3B_03990	1.833e-99	325.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,2P24Y@2433|Roseobacter	28211|Alphaproteobacteria	D	Cell division ATP-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS1_k127_4680744_7	1535287.JP74_07435	9.728e-05	45.0	COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,2UFG2@28211|Alphaproteobacteria,3N78M@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS1_k127_4680744_5	1123237.Salmuc_00701	2.538e-70	241.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,2U7D9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4680744_1	391589.RGAI101_4106	3.268e-127	411.0	COG0121@1|root,COG0121@2|Bacteria,1PX9W@1224|Proteobacteria,2U07B@28211|Alphaproteobacteria,2P3RM@2433|Roseobacter	28211|Alphaproteobacteria	S	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
CMS1_k127_4680744_6	1469613.JT55_09660	6.674e-62	221.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,3FEBR@34008|Rhodovulum	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Erythro_esteras,Pribosyltran
CMS1_k127_4680744_0	1208323.B30_02815	5.311e-166	531.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4680744_3	1208323.B30_02810	2.874e-104	342.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4680744_4	1469613.JT55_11235	3.375e-83	282.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2TTRG@28211|Alphaproteobacteria,3FE7S@34008|Rhodovulum	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_4685863_6	1354722.JQLS01000008_gene736	2.154e-114	372.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria,46Q3M@74030|Roseovarius	28211|Alphaproteobacteria	C	Nitroreductase family	MA20_06710	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_4685863_3	266834.SM_b20270	7.6e-154	492.0	COG3938@1|root,COG3938@2|Bacteria,1N02K@1224|Proteobacteria,2VGM8@28211|Alphaproteobacteria,4B93W@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the proline racemase family	-	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0050346	-	-	-	-	-	-	-	-	-	-	Pro_racemase
CMS1_k127_4685863_2	391613.RTM1035_05660	2.121e-193	608.0	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,2U0YM@28211|Alphaproteobacteria,46PHJ@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	zf-RRN7
CMS1_k127_4685863_7	571166.KI421509_gene3136	9.992e-73	246.0	COG0251@1|root,COG0251@2|Bacteria,1QDUS@1224|Proteobacteria,2U8KG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_4685863_1	1354722.JQLS01000008_gene738	1.129e-213	668.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,2TRUP@28211|Alphaproteobacteria,46P0W@74030|Roseovarius	28211|Alphaproteobacteria	S	virion core protein (lumpy skin disease virus)	ydjI	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
CMS1_k127_4685863_4	1288298.rosmuc_03083	3.245e-150	484.0	2BWZZ@1|root,2Z86E@2|Bacteria,1MW89@1224|Proteobacteria,2U08W@28211|Alphaproteobacteria,46NYH@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2927)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2927
CMS1_k127_4685863_0	1288298.rosmuc_03084	2.352e-220	687.0	COG3853@1|root,COG3853@2|Bacteria,1MZ3B@1224|Proteobacteria,2TQZD@28211|Alphaproteobacteria,46PNT@74030|Roseovarius	28211|Alphaproteobacteria	P	protein involved in tellurite resistance	telA	-	-	-	-	-	-	-	-	-	-	-	TelA
CMS1_k127_4685863_5	1288298.rosmuc_03085	9.311e-141	450.0	COG4915@1|root,COG4915@2|Bacteria,1P3PC@1224|Proteobacteria,2TT04@28211|Alphaproteobacteria,46NS5@74030|Roseovarius	28211|Alphaproteobacteria	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
CMS1_k127_4686510_4	391613.RTM1035_07318	1.459e-38	145.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,2TU1M@28211|Alphaproteobacteria,46NGD@74030|Roseovarius	28211|Alphaproteobacteria	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4686510_0	391613.RTM1035_07313	8.218e-184	576.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,2TQUF@28211|Alphaproteobacteria,46PQS@74030|Roseovarius	28211|Alphaproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
CMS1_k127_4686510_2	1354722.JQLS01000008_gene1715	1.341e-145	467.0	COG2267@1|root,COG2267@2|Bacteria,1MW9H@1224|Proteobacteria,2U1YC@28211|Alphaproteobacteria,46NP5@74030|Roseovarius	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_4686510_1	314264.ROS217_18617	9.563e-162	512.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,46PXZ@74030|Roseovarius	28211|Alphaproteobacteria	S	Polyphosphate kinase 2	ppk_2	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0042802,GO:0044237	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
CMS1_k127_4686510_3	1461694.ATO9_14925	1.193e-56	203.0	COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,2TUIH@28211|Alphaproteobacteria,2PCN8@252301|Oceanicola	28211|Alphaproteobacteria	K	WHG domain	MA20_04045	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS1_k127_4691696_0	1288298.rosmuc_03442	1.311e-90	304.0	COG0345@1|root,COG0345@2|Bacteria,1R59T@1224|Proteobacteria,2U3V2@28211|Alphaproteobacteria,46NEJ@74030|Roseovarius	28211|Alphaproteobacteria	E	NADP oxidoreductase coenzyme F420-dependent	proC1	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS1_k127_4691696_1	1354722.JQLS01000008_gene538	8.936e-52	188.0	2C5RM@1|root,340TY@2|Bacteria,1NYT5@1224|Proteobacteria,2UTTD@28211|Alphaproteobacteria,46QRD@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4703884_1	391613.RTM1035_14707	5.464e-67	229.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,46PBJ@74030|Roseovarius	28211|Alphaproteobacteria	V	COG0842 ABC-type multidrug transport system, permease component	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_4703884_2	1354722.JQLS01000008_gene2424	5.83e-46	168.0	2E38C@1|root,32Y82@2|Bacteria,1N7QR@1224|Proteobacteria,2UFKA@28211|Alphaproteobacteria,46R20@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4703884_0	1354722.JQLS01000008_gene2423	4.925e-139	447.0	COG0616@1|root,COG0616@2|Bacteria,1MY1I@1224|Proteobacteria,2U07G@28211|Alphaproteobacteria,46RIE@74030|Roseovarius	28211|Alphaproteobacteria	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
CMS1_k127_4703884_3	1288298.rosmuc_02769	1.938e-10	66.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,46RWR@74030|Roseovarius	28211|Alphaproteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
CMS1_k127_4712469_3	391613.RTM1035_11938	4.437e-22	100.0	2BZ7K@1|root,33C4A@2|Bacteria,1NI11@1224|Proteobacteria,2UJJV@28211|Alphaproteobacteria,46R7E@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4712469_2	391613.RTM1035_11933	1.293e-50	183.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,46R3M@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS1_k127_4712469_1	571166.KI421509_gene2136	3.314e-65	225.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	MA20_13155	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_4712469_0	391613.RTM1035_02920	1.795e-149	474.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,46Q7V@74030|Roseovarius	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
CMS1_k127_4715605_4	1288298.rosmuc_01568	2.526e-165	522.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,46NYD@74030|Roseovarius	28211|Alphaproteobacteria	T	COG3852 Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_4715605_3	1354722.JQLS01000008_gene1416	3.958e-262	811.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,46NTR@74030|Roseovarius	28211|Alphaproteobacteria	T	Containing CheY-like receiver, AAA-type ATPase, and DNA-binding	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
CMS1_k127_4715605_0	1288298.rosmuc_01570	0.0	1246.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,46P79@74030|Roseovarius	28211|Alphaproteobacteria	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	ntrY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_4715605_2	1354722.JQLS01000008_gene1414	2.068e-263	816.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,46NYA@74030|Roseovarius	28211|Alphaproteobacteria	T	Containing CheY-like receiver, AAA-type ATPase, and DNA-binding	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_4715605_6	981384.AEYW01000006_gene2895	1.872e-29	123.0	2AJH7@1|root,31A3Q@2|Bacteria,1MYWG@1224|Proteobacteria,2UAKX@28211|Alphaproteobacteria,4NBZX@97050|Ruegeria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4715605_1	1288298.rosmuc_01318	4.219e-269	831.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2TRP9@28211|Alphaproteobacteria,46NX9@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0569 K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_4715605_5	1354722.JQLS01000008_gene1737	3.444e-79	267.0	COG0168@1|root,COG0168@2|Bacteria,1MWV4@1224|Proteobacteria,2TQP5@28211|Alphaproteobacteria,46PMU@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0168 Trk-type K transport systems, membrane components	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_4720225_3	1288298.rosmuc_00591	1.078e-125	403.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,46QHF@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS1_k127_4720225_2	351016.RAZWK3B_10652	3.347e-209	654.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2P2NB@2433|Roseobacter	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_4720225_4	314264.ROS217_11801	2.773e-81	276.0	2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,2UDNJ@28211|Alphaproteobacteria,46PXV@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4720225_0	391613.RTM1035_20436	0.0	1221.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,46NQU@74030|Roseovarius	28211|Alphaproteobacteria	C	Domain of unknown function (DUF4445)	nqrF	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS1_k127_4720225_1	1354722.JQLS01000008_gene2931	7.307e-304	938.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,2TR1X@28211|Alphaproteobacteria,46P6M@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
CMS1_k127_4720225_5	1354722.JQLS01000008_gene2930	7.458e-38	143.0	COG1522@1|root,COG1522@2|Bacteria,1MZDV@1224|Proteobacteria,2UBTU@28211|Alphaproteobacteria,46R76@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1522 Transcriptional regulators	QU41_18010	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
CMS1_k127_4722402_2	1279038.KB907337_gene173	7.867e-14	78.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YbaK prolyl-tRNA synthetase associated	ybaK	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS1_k127_4722402_0	156889.Mmc1_1089	3.201e-127	413.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,dCache_1,sCache_3_3
CMS1_k127_4722402_3	285535.JOEY01000035_gene3715	9.226e-07	53.0	COG0477@1|root,COG0477@2|Bacteria,2H6BY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4722402_1	570952.ATVH01000011_gene570	7.75e-35	138.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2U9A5@28211|Alphaproteobacteria,2JT8M@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_4735486_0	1122614.JHZF01000013_gene3997	1.434e-141	458.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2PCWG@252301|Oceanicola	28211|Alphaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS1_k127_4735486_1	1354722.JQLS01000008_gene2381	1.777e-141	454.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,46PXT@74030|Roseovarius	28211|Alphaproteobacteria	L	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_475162_3	999550.KI421507_gene3243	8.592e-86	285.0	COG1593@1|root,COG1593@2|Bacteria,1QNVU@1224|Proteobacteria,2U0UE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system large permease component	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
CMS1_k127_475162_2	999550.KI421507_gene3244	1.092e-90	304.0	COG3090@1|root,COG3090@2|Bacteria,1REUZ@1224|Proteobacteria,2U2HI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TRAP-type C4-dicarboxylate transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_475162_1	314262.MED193_13183	1.367e-253	786.0	COG1638@1|root,COG1638@2|Bacteria,1P574@1224|Proteobacteria,2TUDW@28211|Alphaproteobacteria,2P1A8@2433|Roseobacter	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_475162_0	351016.RAZWK3B_01125	1.32e-309	953.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2P20B@2433|Roseobacter	28211|Alphaproteobacteria	C	COG2303 Choline dehydrogenase and related flavoproteins	alkJ2	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_475162_4	1342299.Z947_2195	3.08e-11	63.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria,3ZYKU@60136|Sulfitobacter	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_4754352_2	391589.RGAI101_3501	6.85e-28	114.0	COG0446@1|root,COG3453@1|root,COG0446@2|Bacteria,COG3453@2|Bacteria,1N5MC@1224|Proteobacteria,2TW6Z@28211|Alphaproteobacteria,2P0YR@2433|Roseobacter	28211|Alphaproteobacteria	S	Putative phosphatase (DUF442)	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442,Pyr_redox_2
CMS1_k127_4754352_0	571166.KI421509_gene4159	2.549e-174	550.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_4754352_1	83219.PM02_05175	9.153e-109	355.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2TU8X@28211|Alphaproteobacteria,3ZX27@60136|Sulfitobacter	28211|Alphaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_4761612_1	571166.KI421509_gene3322	3.652e-243	755.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2U2TJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	nitrite reductase	nirS	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
CMS1_k127_4761612_0	571166.KI421509_gene3323	3.295e-276	875.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2TR0X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CK	COG3901 Regulator of nitric oxide reductase transcription	nirI	-	-	ko:K19343	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4_5
CMS1_k127_4767288_4	89187.ISM_08315	0.0006693	43.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,46P12@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4767288_1	375451.RD1_2918	2.775e-235	739.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,2TSSD@28211|Alphaproteobacteria,2P26H@2433|Roseobacter	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	adhE	-	1.2.1.81,1.2.1.87	ko:K13922,ko:K15515	ko00640,map00640	-	R09097	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_4767288_2	314270.RB2083_1550	3.813e-185	582.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3ZI2R@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_4767288_3	375451.RD1_2921	7.197e-72	249.0	299HC@1|root,2ZWK0@2|Bacteria,1REI8@1224|Proteobacteria,2U7I7@28211|Alphaproteobacteria,2P35Y@2433|Roseobacter	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
CMS1_k127_4767288_0	391595.RLO149_c015160	2.404e-242	752.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2P27H@2433|Roseobacter	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_4773338_10	314264.ROS217_13186	6.129e-16	80.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UD2M@28211|Alphaproteobacteria,46QZJ@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442
CMS1_k127_4773338_8	314264.ROS217_13181	2.79e-62	217.0	COG0589@1|root,COG0589@2|Bacteria,1RDMJ@1224|Proteobacteria,2U769@28211|Alphaproteobacteria,46NPR@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_4773338_1	1354722.JQLS01000008_gene271	1.8e-306	942.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2TQVA@28211|Alphaproteobacteria,46QIC@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1115 Na alanine symporter	alsT	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS1_k127_4773338_4	1288298.rosmuc_02306	3.355e-223	698.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2TRMX@28211|Alphaproteobacteria,46NRP@74030|Roseovarius	28211|Alphaproteobacteria	S	Peptidase, M16 family protein	MA20_05660	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_4773338_3	1354722.JQLS01000008_gene278	4.945e-226	706.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,46Q4F@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_4773338_7	1354722.JQLS01000008_gene279	9.959e-81	272.0	2AJ3A@1|root,319MP@2|Bacteria,1RHJE@1224|Proteobacteria,2UABS@28211|Alphaproteobacteria,46QI1@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3035)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3035
CMS1_k127_4773338_6	1354722.JQLS01000008_gene280	1.973e-89	296.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,46PZM@74030|Roseovarius	28211|Alphaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS1_k127_4773338_2	89187.ISM_06445	2.59e-295	911.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,46NHY@74030|Roseovarius	28211|Alphaproteobacteria	F	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_4773338_0	1354722.JQLS01000008_gene282	9.911e-312	962.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,46P0G@74030|Roseovarius	28211|Alphaproteobacteria	S	Heparinase II/III-like protein	MA20_25080	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_4773338_5	314264.ROS217_13236	4.086e-220	688.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria,46PNN@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
CMS1_k127_4773338_9	314232.SKA53_12703	1.899e-23	102.0	COG5508@1|root,COG5508@2|Bacteria,1QS3A@1224|Proteobacteria,2VAW6@28211|Alphaproteobacteria,2P97P@245186|Loktanella	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1674)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1674
CMS1_k127_4775560_2	571166.KI421509_gene3161	9.962e-153	484.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS1_k127_4775560_5	1354722.JQLS01000008_gene868	1.174e-77	264.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,46QBY@74030|Roseovarius	28211|Alphaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS1_k127_4775560_3	1354722.JQLS01000008_gene869	8.765e-149	475.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,46NYS@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1253 Hemolysins and related proteins containing CBS domains	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
CMS1_k127_4775560_1	391613.RTM1035_12283	2.293e-225	708.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,46Q5T@74030|Roseovarius	28211|Alphaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS1_k127_4775560_0	1288298.rosmuc_03171	7.22e-235	730.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,46QFV@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_4775560_4	1354722.JQLS01000008_gene872	8.139e-115	370.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,46Q0Q@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS1_k127_4778225_0	1402135.SUH3_07850	3.745e-43	161.0	2E5FX@1|root,3307M@2|Bacteria,1N8E5@1224|Proteobacteria,2UAZZ@28211|Alphaproteobacteria,3ZZ17@60136|Sulfitobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4778225_1	318586.Pden_4094	7.183e-34	149.0	2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4778225_2	420324.KI911964_gene387	7.859e-15	88.0	2DBSR@1|root,2ZATG@2|Bacteria,1R9D8@1224|Proteobacteria,2U2M7@28211|Alphaproteobacteria,1JXHP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4780264_4	391613.RTM1035_16802	2.416e-177	557.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,46P2M@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008714,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
CMS1_k127_4780264_15	314264.ROS217_11431	2.313e-48	174.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2U9AI@28211|Alphaproteobacteria,46R31@74030|Roseovarius	28211|Alphaproteobacteria	L	Belongs to the bacterial histone-like protein family	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_4780264_6	314264.ROS217_12576	1.506e-160	509.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2TR27@28211|Alphaproteobacteria,46ND6@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_19820	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4780264_2	314264.ROS217_12571	3.171e-222	691.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2TQY2@28211|Alphaproteobacteria,46NZB@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS1_k127_4780264_12	1288298.rosmuc_01816	7.015e-80	275.0	COG1999@1|root,COG1999@2|Bacteria,1RJQG@1224|Proteobacteria,2UB6C@28211|Alphaproteobacteria,46NBU@74030|Roseovarius	28211|Alphaproteobacteria	S	involved in biogenesis of respiratory and photosynthetic	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_4780264_9	1354722.JQLS01000001_gene4663	4.971e-92	307.0	2DKZF@1|root,30ZZW@2|Bacteria,1REBT@1224|Proteobacteria,2U7TQ@28211|Alphaproteobacteria,46NV1@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4780264_13	1354722.JQLS01000001_gene4664	4.816e-73	249.0	2CK2Q@1|root,303GN@2|Bacteria,1RG44@1224|Proteobacteria,2U8BW@28211|Alphaproteobacteria,46QQN@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4780264_8	314264.ROS217_12561	2.358e-92	305.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2VG85@28211|Alphaproteobacteria,46PI7@74030|Roseovarius	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
CMS1_k127_4780264_3	1354722.JQLS01000008_gene2849	7.034e-183	575.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,46PEK@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0583 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4780264_11	314264.ROS217_12551	1.118e-80	276.0	2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria,2U9CM@28211|Alphaproteobacteria,46QR6@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
CMS1_k127_4780264_0	314264.ROS217_12546	0.0	1172.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,46P7R@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS1_k127_4780264_14	1469613.JT55_00155	1.262e-67	233.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,3FD9Y@34008|Rhodovulum	28211|Alphaproteobacteria	J	RF-1 domain	MA20_05665	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS1_k127_4780264_7	1354722.JQLS01000008_gene3676	2.226e-147	473.0	COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,2TR3K@28211|Alphaproteobacteria,46QGU@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3770 Murein endopeptidase	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
CMS1_k127_4780264_1	1354722.JQLS01000008_gene3675	5.522e-258	799.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2TSCV@28211|Alphaproteobacteria,46NSV@74030|Roseovarius	28211|Alphaproteobacteria	S	COG2270 Permeases of the major facilitator superfamily	MA20_25070	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS1_k127_4780264_10	1288298.rosmuc_00437	5.379e-92	305.0	COG0824@1|root,COG0824@2|Bacteria,1RCSP@1224|Proteobacteria,2U6RM@28211|Alphaproteobacteria,46QKS@74030|Roseovarius	28211|Alphaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
CMS1_k127_4780264_16	1288298.rosmuc_00436	3.511e-46	179.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,46R3C@74030|Roseovarius	28211|Alphaproteobacteria	S	Integral membrane protein	MA20_25225	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CMS1_k127_4780264_5	1288298.rosmuc_00435	8.433e-168	530.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,46QB7@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0514 Superfamily II DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS1_k127_4788228_1	351016.RAZWK3B_19051	1.022e-77	263.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2U79E@28211|Alphaproteobacteria,2P34U@2433|Roseobacter	28211|Alphaproteobacteria	G	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
CMS1_k127_4788228_0	1288298.rosmuc_02000	1.19e-136	439.0	COG0604@1|root,COG0604@2|Bacteria,1MXRX@1224|Proteobacteria,2TRSQ@28211|Alphaproteobacteria,46PC4@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4793330_2	1288298.rosmuc_00342	5.964e-113	367.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,46PM5@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	MA20_43170	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
CMS1_k127_4793330_0	1288298.rosmuc_00341	1.029e-236	737.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,46PP8@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_4793330_1	1354722.JQLS01000008_gene3595	1.132e-178	564.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TS46@28211|Alphaproteobacteria,46PPV@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
CMS1_k127_4793330_3	351016.RAZWK3B_01245	5.182e-85	286.0	COG3090@1|root,COG3090@2|Bacteria,1N0N7@1224|Proteobacteria,2U65H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG3090 TRAP-type C4-dicarboxylate transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_4793330_4	351016.RAZWK3B_01240	4.562e-81	272.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2P1AX@2433|Roseobacter	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	tauM	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_4798945_2	1288298.rosmuc_03322	1.51e-187	587.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,46NCW@74030|Roseovarius	28211|Alphaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS1_k127_4798945_7	83219.PM02_07400	8.777e-50	179.0	COG0347@1|root,COG0347@2|Bacteria,1RIRQ@1224|Proteobacteria,2UA55@28211|Alphaproteobacteria,3ZXSK@60136|Sulfitobacter	28211|Alphaproteobacteria	E	nitrogen regulatory protein PII	-	-	-	-	-	-	-	-	-	-	-	-	DUF190
CMS1_k127_4798945_3	83219.PM02_07395	1.253e-143	462.0	COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,2TRK2@28211|Alphaproteobacteria,3ZW00@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
CMS1_k127_4798945_6	314264.ROS217_18517	1.172e-60	211.0	2DQZ1@1|root,339GH@2|Bacteria,1NFR2@1224|Proteobacteria,2UIMZ@28211|Alphaproteobacteria,46QVM@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4798945_0	1354722.JQLS01000008_gene1763	3.674e-252	783.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,46NEN@74030|Roseovarius	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
CMS1_k127_4798945_1	314264.ROS217_17972	6.252e-234	727.0	COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,46NMH@74030|Roseovarius	28211|Alphaproteobacteria	S	Portal protein, HK97 family	gp34	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
CMS1_k127_4798945_8	1354722.JQLS01000008_gene1069	6.559e-31	123.0	2E4PR@1|root,32ZID@2|Bacteria,1N6SB@1224|Proteobacteria,2UFAU@28211|Alphaproteobacteria,46R78@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4798945_5	391613.RTM1035_10730	8.588e-87	292.0	COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2UD3U@28211|Alphaproteobacteria,46QIN@74030|Roseovarius	28211|Alphaproteobacteria	S	Phage prohead protease, HK97 family protein	-	-	-	ko:K06904	-	-	-	-	ko00000	-	-	-	Peptidase_S78
CMS1_k127_4798945_4	1288298.rosmuc_03448	7.322e-121	392.0	COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria,46PXJ@74030|Roseovarius	28211|Alphaproteobacteria	S	phage phi-C31 gp36 major capsid-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
CMS1_k127_4806234_2	391613.RTM1035_11835	2.961e-108	355.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,46NJN@74030|Roseovarius	28211|Alphaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9,3.1.3.15,4.2.1.19	ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03013,R03243,R03457	RC00006,RC00017,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	IGPD
CMS1_k127_4806234_1	1354722.JQLS01000008_gene1840	1.845e-126	405.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2TTT4@28211|Alphaproteobacteria,46NVN@74030|Roseovarius	28211|Alphaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_4806234_3	1354722.JQLS01000008_gene1842	1.649e-74	252.0	COG0346@1|root,COG0346@2|Bacteria,1RIN8@1224|Proteobacteria,2U9WM@28211|Alphaproteobacteria,46QSU@74030|Roseovarius	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_4806234_4	391613.RTM1035_11820	1.428e-53	191.0	COG4731@1|root,COG4731@2|Bacteria,1RHN9@1224|Proteobacteria,2U9SP@28211|Alphaproteobacteria,46QR1@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
CMS1_k127_4806234_0	246200.SPO1158	8.497e-134	431.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,4NBK5@97050|Ruegeria	28211|Alphaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_4806234_5	1288298.rosmuc_03270	8.884e-10	59.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,2UBVK@28211|Alphaproteobacteria,46QNU@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	ccrB	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_4810387_8	501479.ACNW01000058_gene4413	2.422e-42	161.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2U17W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_7,PAS_9,Response_reg
CMS1_k127_4810387_10	1415756.JQMY01000001_gene679	6.53e-07	53.0	COG4256@1|root,COG4256@2|Bacteria,1NHM0@1224|Proteobacteria,2UJD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Hemin uptake protein hemP	-	-	-	-	-	-	-	-	-	-	-	-	hemP
CMS1_k127_4810387_7	398580.Dshi_2051	1.355e-62	218.0	28JPI@1|root,2Z9FJ@2|Bacteria,1R98Y@1224|Proteobacteria,2U4GH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4810387_9	1415756.JQMY01000001_gene681	1.5e-40	151.0	COG2906@1|root,COG2906@2|Bacteria,1N0J0@1224|Proteobacteria,2UD47@28211|Alphaproteobacteria,2PEHS@252301|Oceanicola	28211|Alphaproteobacteria	P	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
CMS1_k127_4810387_5	633131.TR2A62_0087	3.964e-92	306.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2U70I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS1_k127_4810387_0	1342302.JASC01000013_gene2721	0.0	1107.0	COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,2TR91@28211|Alphaproteobacteria,3ZW25@60136|Sulfitobacter	28211|Alphaproteobacteria	CE	AIR synthase related protein, C-terminal domain	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
CMS1_k127_4810387_3	1443111.JASG01000004_gene608	1.161e-160	512.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2TS2E@28211|Alphaproteobacteria,3ZVSX@60136|Sulfitobacter	28211|Alphaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	ybbB	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
CMS1_k127_4810387_1	1342301.JASD01000006_gene68	1.91e-216	676.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,3ZYXC@60136|Sulfitobacter	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4810387_2	1342301.JASD01000006_gene67	9.578e-210	657.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3ZVPT@60136|Sulfitobacter	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_4810387_4	1342301.JASD01000006_gene66	1.275e-156	497.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2TUQK@28211|Alphaproteobacteria,3ZWPC@60136|Sulfitobacter	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4810387_6	391619.PGA1_c23400	2.381e-91	306.0	COG1349@1|root,COG1349@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
CMS1_k127_4816619_3	1305735.JAFT01000005_gene1627	3.446e-39	147.0	2C3PP@1|root,2Z954@2|Bacteria,1MXGR@1224|Proteobacteria,2TS01@28211|Alphaproteobacteria,2PDY7@252301|Oceanicola	28211|Alphaproteobacteria	S	Branched-chain amino acid aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4816619_1	1354722.JQLS01000008_gene3493	3.461e-97	325.0	COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,2U77D@28211|Alphaproteobacteria,46PJ7@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
CMS1_k127_4816619_0	351016.RAZWK3B_02900	1.019e-172	545.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TQR9@28211|Alphaproteobacteria,2P211@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_4816619_2	314264.ROS217_09762	1.774e-61	215.0	COG0225@1|root,COG0225@2|Bacteria,1R5GQ@1224|Proteobacteria,2VGNN@28211|Alphaproteobacteria,46NBC@74030|Roseovarius	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_2	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_4822630_1	1354722.JQLS01000008_gene762	0.0	1023.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,46NY5@74030|Roseovarius	28211|Alphaproteobacteria	G	COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_4822630_0	1305735.JAFT01000005_gene506	0.0	1090.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria,2PD7U@252301|Oceanicola	28211|Alphaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS1_k127_4831952_0	1288298.rosmuc_00479	0.0	1281.0	28H8H@1|root,2Z7KE@2|Bacteria,1MV77@1224|Proteobacteria,2TSVV@28211|Alphaproteobacteria,46P48@74030|Roseovarius	28211|Alphaproteobacteria	S	Aerotolerance regulator N-terminal	MA20_44655	-	-	-	-	-	-	-	-	-	-	-	BatA,DUF4159
CMS1_k127_4831952_1	1288298.rosmuc_00480	0.0	1189.0	COG5426@1|root,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,2TQNQ@28211|Alphaproteobacteria,46QEF@74030|Roseovarius	28211|Alphaproteobacteria	S	membrane	MA20_44660	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
CMS1_k127_4831952_6	1354722.JQLS01000008_gene3628	4.969e-53	189.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria,46R3R@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4831952_5	314264.ROS217_09010	1.641e-101	335.0	COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,2TTTD@28211|Alphaproteobacteria,46PRK@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function, DUF599	-	-	-	-	-	-	-	-	-	-	-	-	DUF599
CMS1_k127_4831952_2	1288298.rosmuc_00483	1.333e-284	878.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria,46PE7@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_4831952_3	1288298.rosmuc_00484	4.01e-176	560.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria,46PP0@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_4831952_4	314264.ROS217_08995	3.158e-132	422.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,46Q6E@74030|Roseovarius	28211|Alphaproteobacteria	C	Glycolate oxidase, iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
CMS1_k127_4841320_3	1288298.rosmuc_01981	6.556e-26	108.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,46NPQ@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1178 ABC-type Fe3 transport system, permease component	sfuB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS1_k127_4841320_0	1354722.JQLS01000008_gene581	1.162e-150	482.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,2TQS6@28211|Alphaproteobacteria,46PS7@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
CMS1_k127_4841320_1	1354722.JQLS01000008_gene580	5.714e-98	327.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2U97D@28211|Alphaproteobacteria,46PZK@74030|Roseovarius	28211|Alphaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
CMS1_k127_4841320_2	1122614.JHZF01000011_gene821	2.451e-60	209.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,2PDF3@252301|Oceanicola	28211|Alphaproteobacteria	K	CarD-like/TRCF domain	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
CMS1_k127_4849938_2	391613.RTM1035_04835	4.379e-57	199.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,46PN3@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS1_k127_4849938_0	1288298.rosmuc_02891	1.586e-155	497.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,46PP4@74030|Roseovarius	28211|Alphaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_4849938_1	314264.ROS217_15675	1.521e-90	302.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VG8P@28211|Alphaproteobacteria,46PYR@74030|Roseovarius	28211|Alphaproteobacteria	S	aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS1_k127_4852300_0	1300350.DSW25_02310	1.692e-116	377.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,3ZVNW@60136|Sulfitobacter	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
CMS1_k127_4852300_2	1300350.DSW25_02310	1.083e-64	228.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,3ZVNW@60136|Sulfitobacter	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
CMS1_k127_4852300_1	391589.RGAI101_2131	4.671e-91	302.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,2P0ZB@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1271 Cytochrome bd-type quinol oxidase, subunit 1	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
CMS1_k127_4853217_0	1305735.JAFT01000005_gene2539	6.554e-193	607.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2PDWT@252301|Oceanicola	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_4853217_4	1305735.JAFT01000005_gene2540	5.216e-78	264.0	COG4665@1|root,COG4665@2|Bacteria,1RE14@1224|Proteobacteria,2U5M8@28211|Alphaproteobacteria,2PDY1@252301|Oceanicola	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_4853217_1	398580.Dshi_3153	1.023e-182	576.0	COG1638@1|root,COG1638@2|Bacteria,1MUBS@1224|Proteobacteria,2TUKV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	dctP5	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_4853217_2	388739.RSK20926_00175	2.13e-131	425.0	COG4336@1|root,COG4336@2|Bacteria,1MW52@1224|Proteobacteria,2TST8@28211|Alphaproteobacteria,2P1MF@2433|Roseobacter	28211|Alphaproteobacteria	S	Belongs to the D-glutamate cyclase family	MA20_16485	-	-	-	-	-	-	-	-	-	-	-	DUF1445
CMS1_k127_4853217_3	384765.SIAM614_22137	9.255e-104	342.0	COG0583@1|root,COG0583@2|Bacteria,1QU1H@1224|Proteobacteria,2U0TE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4883710_3	1354722.JQLS01000008_gene1245	1.275e-12	68.0	COG1585@1|root,COG1585@2|Bacteria,1NA05@1224|Proteobacteria,2UFXG@28211|Alphaproteobacteria,46R6Z@74030|Roseovarius	28211|Alphaproteobacteria	OU	COG1585 Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS1_k127_4883710_2	999611.KI421504_gene2364	2.418e-140	450.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,280X7@191028|Leisingera	28211|Alphaproteobacteria	O	SPFH domain / Band 7 family	qmcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
CMS1_k127_4883710_0	1354722.JQLS01000008_gene1247	2.917e-232	721.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,46Q31@74030|Roseovarius	28211|Alphaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_4883710_1	314264.ROS217_19242	9.785e-162	514.0	COG0189@1|root,COG0189@2|Bacteria,1Q56X@1224|Proteobacteria,2VBK6@28211|Alphaproteobacteria,46RZX@74030|Roseovarius	28211|Alphaproteobacteria	HJ	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
CMS1_k127_4889520_4	314264.ROS217_16371	5.211e-26	111.0	2BD10@1|root,326NA@2|Bacteria,1RK1B@1224|Proteobacteria,2U9VT@28211|Alphaproteobacteria,46R02@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
CMS1_k127_4889520_2	999547.KI421500_gene1449	1.284e-94	312.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria,280YD@191028|Leisingera	28211|Alphaproteobacteria	S	QueF-like protein	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS1_k127_4889520_0	1354722.JQLS01000008_gene641	4.3e-128	413.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,46NZT@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS1_k127_4889520_3	314264.ROS217_16356	3.422e-66	227.0	COG0720@1|root,COG0720@2|Bacteria,1RD4G@1224|Proteobacteria,2U78V@28211|Alphaproteobacteria,46QUH@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS1_k127_4889520_1	1354722.JQLS01000008_gene639	4.431e-128	412.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria,46P7W@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS1_k127_4889520_5	391613.RTM1035_06053	5.147e-17	81.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,46NP6@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4895712_4	1123237.Salmuc_02167	1.336e-76	260.0	2E3HM@1|root,32EQI@2|Bacteria,1NGRR@1224|Proteobacteria,2UK11@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4895712_3	1354722.JQLS01000008_gene3643	2.487e-85	285.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,46NCU@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the UPF0178 family	MA20_27470	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
CMS1_k127_4895712_0	391613.RTM1035_17707	7.049e-291	895.0	COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,2TSG7@28211|Alphaproteobacteria,46PKF@74030|Roseovarius	28211|Alphaproteobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_4895712_2	314264.ROS217_11141	1.97e-163	516.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,46Q1K@74030|Roseovarius	28211|Alphaproteobacteria	S	Serine hydrolase involved in the detoxification of formaldehyde	fghA	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
CMS1_k127_4895712_1	1288298.rosmuc_00044	4.317e-168	531.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2TUJR@28211|Alphaproteobacteria,46NPS@74030|Roseovarius	28211|Alphaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS1_k127_4897242_12	1305735.JAFT01000005_gene3743	0.0001133	44.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,2PCN7@252301|Oceanicola	28211|Alphaproteobacteria	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
CMS1_k127_4897242_0	391613.RTM1035_05320	1.144e-312	960.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,46PN5@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	mmsA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_4897242_4	314264.ROS217_23142	1.764e-162	515.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2TQXV@28211|Alphaproteobacteria,46NUQ@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	gltR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4897242_7	1354722.JQLS01000008_gene1909	2.715e-77	259.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,46QTS@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_4897242_5	1354722.JQLS01000008_gene1908	3.622e-88	293.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria,46PGQ@74030|Roseovarius	28211|Alphaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_4897242_8	1354722.JQLS01000008_gene1905	2.259e-57	204.0	COG2197@1|root,COG2197@2|Bacteria,1RDUR@1224|Proteobacteria,2U7E1@28211|Alphaproteobacteria,46RI8@74030|Roseovarius	28211|Alphaproteobacteria	KT	Containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_4897242_6	1354722.JQLS01000008_gene1904	2.554e-80	271.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2U7CQ@28211|Alphaproteobacteria,46RIU@74030|Roseovarius	28211|Alphaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_4897242_9	1354722.JQLS01000008_gene1903	1.81e-16	81.0	2C6TI@1|root,33DVM@2|Bacteria,1NM8W@1224|Proteobacteria,2UK0W@28211|Alphaproteobacteria,46RZV@74030|Roseovarius	28211|Alphaproteobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
CMS1_k127_4897242_2	1288298.rosmuc_02952	4.224e-202	632.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,46NPG@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_4897242_1	571166.KI421509_gene1176	3.718e-240	758.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2TRF9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Na phosphate symporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
CMS1_k127_4897242_10	571166.KI421509_gene1175	2.416e-11	67.0	2ECRF@1|root,336P6@2|Bacteria,1NFZ8@1224|Proteobacteria,2UIKP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4897242_3	391626.OAN307_c42350	2.553e-171	546.0	COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,2TS1I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the heat shock protein 70 family	MA20_15110	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CMS1_k127_4918420_2	1354722.JQLS01000008_gene3537	3.221e-161	510.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,46NBZ@74030|Roseovarius	28211|Alphaproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	soxA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019418,GO:0019538,GO:0020037,GO:0022900,GO:0032991,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0070069,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
CMS1_k127_4918420_0	1288298.rosmuc_00230	0.0	1078.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TUAE@28211|Alphaproteobacteria,46Q9R@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C,Metallophos
CMS1_k127_4918420_1	391613.RTM1035_18745	6.487e-254	785.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,46NHJ@74030|Roseovarius	28211|Alphaproteobacteria	S	COG2041 Sulfite oxidase and related enzymes	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS1_k127_4918420_3	439496.RBY4I_1307	7.338e-150	484.0	COG3258@1|root,COG3474@1|root,COG3258@2|Bacteria,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome	soxD	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_4918420_4	391613.RTM1035_18755	9.72e-112	364.0	COG2863@1|root,COG3474@1|root,COG2863@2|Bacteria,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,46NFR@74030|Roseovarius	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	soxE	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_4927265_5	351016.RAZWK3B_01685	6.495e-59	208.0	COG0280@1|root,COG0280@2|Bacteria,1QTS5@1224|Proteobacteria,2TVFP@28211|Alphaproteobacteria,2P2KF@2433|Roseobacter	28211|Alphaproteobacteria	H	Phosphate acetyl/butaryl transferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
CMS1_k127_4927265_0	391613.RTM1035_16562	0.0	1128.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2TTAQ@28211|Alphaproteobacteria,46NDF@74030|Roseovarius	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	xsc	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_4927265_1	1354722.JQLS01000008_gene2913	8.529e-290	893.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,46NXX@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	tauR	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
CMS1_k127_4927265_7	1469613.JT55_16375	0.0001851	48.0	COG5470@1|root,COG5470@2|Bacteria,1RIH6@1224|Proteobacteria,2U9VZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NIPSNAP family containing protein	MA20_35555	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
CMS1_k127_4927265_4	1354722.JQLS01000008_gene2910	1.23e-60	213.0	COG2329@1|root,COG2329@2|Bacteria,1RGVV@1224|Proteobacteria,2U9A3@28211|Alphaproteobacteria,46QXT@74030|Roseovarius	28211|Alphaproteobacteria	S	Involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_4927265_3	1288298.rosmuc_00736	4.485e-84	282.0	2DCBQ@1|root,32TZD@2|Bacteria,1N164@1224|Proteobacteria,2UJG3@28211|Alphaproteobacteria,46Q7H@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4927265_6	391613.RTM1035_16532	6.69e-58	206.0	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2U9DU@28211|Alphaproteobacteria,46QVF@74030|Roseovarius	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_4927265_2	1288298.rosmuc_00591	9.699e-120	387.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,46QHF@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS1_k127_4929003_1	1354722.JQLS01000008_gene1684	3.244e-229	716.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2TRWD@28211|Alphaproteobacteria,46Q5J@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0729 Outer membrane protein	tamA	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
CMS1_k127_4929003_0	1354722.JQLS01000008_gene1685	2.047e-271	850.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,46NIG@74030|Roseovarius	28211|Alphaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS1_k127_4939203_5	314264.ROS217_23462	1.544e-07	53.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,46Q6B@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
CMS1_k127_4939203_0	391613.RTM1035_04970	0.0	1105.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,46NNE@74030|Roseovarius	28211|Alphaproteobacteria	H	Cobalt chelatase, pCobT subunit	cobT	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
CMS1_k127_4939203_2	1288298.rosmuc_02924	9.634e-208	647.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,46PMQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Cobalt chelatase, CobS subunit	cobS	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C,CobS_N
CMS1_k127_4939203_4	314264.ROS217_23442	3.724e-156	496.0	COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,46NB2@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_4939203_3	1288298.rosmuc_02927	7.49e-178	561.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2TQW3@28211|Alphaproteobacteria,46NHT@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	1.1.1.31,4.2.1.17	ko:K00020,ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05066,R05595,R06411,R06412,R06942,R08093	RC00099,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
CMS1_k127_4939203_1	1354722.JQLS01000008_gene831	2.97e-230	717.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,46NXR@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	MA20_27425	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4963627_2	391613.RTM1035_12508	3.232e-64	221.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,46QB8@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_4963627_1	314264.ROS217_20837	2.338e-136	438.0	COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,2U1T4@28211|Alphaproteobacteria,46P65@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, AraC family	pobR	-	-	ko:K18954	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
CMS1_k127_4963627_0	1288298.rosmuc_01493	2.304e-156	497.0	COG0747@1|root,COG0747@2|Bacteria,1MXQ4@1224|Proteobacteria,2TTIZ@28211|Alphaproteobacteria,46PIU@74030|Roseovarius	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4973835_2	89187.ISM_05755	9.803e-13	67.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,46NXC@74030|Roseovarius	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_4973835_1	89187.ISM_11860	9.76e-68	236.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2UG08@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	ABM,Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
CMS1_k127_4973835_0	1354722.JQLS01000008_gene2855	7.58e-124	404.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2U5CF@28211|Alphaproteobacteria,46P5H@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4999969_4	391616.OA238_c03360	9.257e-17	79.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2TSXP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
CMS1_k127_4999969_0	1120983.KB894573_gene437	5.251e-64	224.0	COG3791@1|root,COG3791@2|Bacteria,1RD31@1224|Proteobacteria,2U7QB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating, GFA	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_4999969_2	388399.SSE37_22075	1.074e-53	190.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2U9T4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
CMS1_k127_4999969_1	1305735.JAFT01000005_gene1225	1.198e-54	193.0	COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,2U947@28211|Alphaproteobacteria,2PEGI@252301|Oceanicola	28211|Alphaproteobacteria	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
CMS1_k127_4999969_3	246200.SPO1711	2.347e-32	128.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2U57R@28211|Alphaproteobacteria,4NBXJ@97050|Ruegeria	28211|Alphaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
CMS1_k127_5002031_0	391613.RTM1035_06383	0.0	1336.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,46P7F@74030|Roseovarius	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_5002031_1	1354722.JQLS01000008_gene687	0.0	1079.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,46QAY@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_5002031_4	1354722.JQLS01000008_gene688	6.987e-149	475.0	COG1173@1|root,COG1173@2|Bacteria,1MU0P@1224|Proteobacteria,2U41N@28211|Alphaproteobacteria,46PHK@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_5002031_2	314264.ROS217_16690	5.769e-169	535.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSIY@28211|Alphaproteobacteria,46PD3@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5002031_5	391613.RTM1035_06423	1.767e-78	265.0	COG0824@1|root,COG0824@2|Bacteria,1MZB3@1224|Proteobacteria,2U7CU@28211|Alphaproteobacteria,46P54@74030|Roseovarius	28211|Alphaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS1_k127_5002031_3	391613.RTM1035_06443	4.351e-153	486.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,46PYY@74030|Roseovarius	28211|Alphaproteobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS1_k127_5002031_6	1123247.AUIJ01000007_gene2778	3.385e-26	108.0	COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,2TRKV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS1_k127_5013024_0	314264.ROS217_08214	8.587e-208	652.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,46PTC@74030|Roseovarius	28211|Alphaproteobacteria	CP	COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	phaD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
CMS1_k127_5013024_4	1288298.rosmuc_00284	2.091e-84	283.0	COG1863@1|root,COG1863@2|Bacteria,1RH9F@1224|Proteobacteria,2U9P6@28211|Alphaproteobacteria,46PH3@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1863 Multisubunit Na H antiporter, MnhE subunit	phaE	-	-	ko:K05562	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MNHE
CMS1_k127_5013024_6	1354722.JQLS01000008_gene3722	1.001e-39	149.0	COG2212@1|root,COG2212@2|Bacteria,1N8WJ@1224|Proteobacteria,2UBVQ@28211|Alphaproteobacteria,46R24@74030|Roseovarius	28211|Alphaproteobacteria	P	COG2212 Multisubunit Na H antiporter, MnhF subunit	phaF	-	-	ko:K05563	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MrpF_PhaF
CMS1_k127_5013024_5	391613.RTM1035_18896	4.049e-59	212.0	COG1320@1|root,COG1320@2|Bacteria,1MZ6Z@1224|Proteobacteria,2UD2X@28211|Alphaproteobacteria,46QXX@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1320 Multisubunit Na H antiporter, MnhG subunit	phaG	-	-	ko:K05564	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	PhaG_MnhG_YufB
CMS1_k127_5013024_1	1354722.JQLS01000008_gene3724	1.639e-184	583.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,46P34@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	ugpC	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505	3.6.3.20	ko:K05816	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.3	-	-	ABC_tran,TOBE_2
CMS1_k127_5013024_3	1354722.JQLS01000008_gene3725	2.453e-165	527.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2TSYA@28211|Alphaproteobacteria,46PMH@74030|Roseovarius	28211|Alphaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	ugpE	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_5013024_2	1354722.JQLS01000008_gene3726	1.02e-177	558.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2TSGN@28211|Alphaproteobacteria,46Q0C@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1175 ABC-type sugar transport systems, permease components	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_5013024_7	391613.RTM1035_17592	2.679e-14	72.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2TQKV@28211|Alphaproteobacteria,46QCB@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
CMS1_k127_5043475_1	391619.PGA1_c09420	5.552e-106	346.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria,34EIT@302485|Phaeobacter	28211|Alphaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
CMS1_k127_5043475_0	1354722.JQLS01000008_gene1829	2.969e-130	423.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5MK@28211|Alphaproteobacteria,46PWE@74030|Roseovarius	28211|Alphaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_5064638_2	1122614.JHZF01000011_gene1971	4.227e-64	221.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,2PDDK@252301|Oceanicola	28211|Alphaproteobacteria	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS1_k127_5064638_0	1288298.rosmuc_03435	1.818e-220	689.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2TR0W@28211|Alphaproteobacteria,46QM1@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	cobB	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CMS1_k127_5064638_1	1354722.JQLS01000008_gene1058	3.817e-147	469.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,46QAK@74030|Roseovarius	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5065828_2	999547.KI421500_gene2737	3.168e-21	96.0	2AH1R@1|root,317AV@2|Bacteria,1RGWA@1224|Proteobacteria,2U976@28211|Alphaproteobacteria,281IC@191028|Leisingera	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5065828_0	1305735.JAFT01000005_gene1807	5.493e-73	248.0	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9DZ@28211|Alphaproteobacteria,2PE61@252301|Oceanicola	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_5065828_1	1294273.roselon_02430	1.456e-48	181.0	2E9XT@1|root,32SG9@2|Bacteria,1N3Q0@1224|Proteobacteria,2UET2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5070500_2	571166.KI421509_gene3594	4.025e-54	197.0	2C73B@1|root,330Z7@2|Bacteria,1N6KX@1224|Proteobacteria,2VGTZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5070500_1	391613.RTM1035_04770	8.198e-139	449.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,46QH7@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_5070500_3	1230476.C207_02391	1.939e-23	109.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2UCCK@28211|Alphaproteobacteria,3JYCU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_5070500_0	1300350.DSW25_02310	1.558e-198	620.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,3ZVNW@60136|Sulfitobacter	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
CMS1_k127_5095033_1	1288298.rosmuc_01413	7.247e-163	524.0	28HN0@1|root,2Z7WE@2|Bacteria,1MXRK@1224|Proteobacteria,2TUQS@28211|Alphaproteobacteria,46P2I@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5095033_0	1354722.JQLS01000008_gene1288	8.226e-168	533.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,46NE3@74030|Roseovarius	28211|Alphaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_5095033_2	1449357.JQLK01000001_gene1711	8.573e-09	63.0	COG0639@1|root,COG0639@2|Bacteria,1WM4Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_5100489_5	314264.ROS217_16740	1.831e-61	214.0	COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,2TRKV@28211|Alphaproteobacteria,46NKK@74030|Roseovarius	28211|Alphaproteobacteria	L	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS1_k127_5100489_4	314264.ROS217_16745	7.437e-68	237.0	2CH7P@1|root,32S5H@2|Bacteria,1MZHV@1224|Proteobacteria,2UD0S@28211|Alphaproteobacteria,46QJK@74030|Roseovarius	28211|Alphaproteobacteria	S	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_5100489_1	1354722.JQLS01000008_gene701	1.608e-172	545.0	COG0057@1|root,COG0057@2|Bacteria,1QYBW@1224|Proteobacteria,2TRPC@28211|Alphaproteobacteria,46NMB@74030|Roseovarius	28211|Alphaproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_5100489_2	1354722.JQLS01000008_gene702	2.52e-122	406.0	COG3087@1|root,COG3087@2|Bacteria,1RISG@1224|Proteobacteria,2U274@28211|Alphaproteobacteria,46PNZ@74030|Roseovarius	28211|Alphaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_5100489_3	391613.RTM1035_06473	2.644e-117	382.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,2TRS7@28211|Alphaproteobacteria,46QE0@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
CMS1_k127_5100489_0	1354722.JQLS01000008_gene704	1.49e-308	950.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,46PPC@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0281 Malic enzyme	dme	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_510526_1	1354722.JQLS01000008_gene2199	8.923e-307	945.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2TTB5@28211|Alphaproteobacteria,46NGM@74030|Roseovarius	28211|Alphaproteobacteria	C	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	COX2,Cupredoxin_1
CMS1_k127_510526_0	1354722.JQLS01000008_gene2198	0.0	1106.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2TR0X@28211|Alphaproteobacteria,46PTW@74030|Roseovarius	28211|Alphaproteobacteria	CK	FMN_bind	nosR	-	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4_5
CMS1_k127_510613_9	314264.ROS217_20977	5.95e-43	157.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,46Q1Q@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	uup	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
CMS1_k127_510613_4	314264.ROS217_20982	8.039e-95	317.0	COG3176@1|root,COG3176@2|Bacteria,1P4U9@1224|Proteobacteria,2U081@28211|Alphaproteobacteria,46PS6@74030|Roseovarius	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
CMS1_k127_510613_5	1354722.JQLS01000008_gene1581	2.728e-78	264.0	COG2913@1|root,COG2913@2|Bacteria,1RHYM@1224|Proteobacteria,2UBU9@28211|Alphaproteobacteria,46QNH@74030|Roseovarius	28211|Alphaproteobacteria	J	COG2913 Small protein A (tmRNA-binding)	MA20_36760	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
CMS1_k127_510613_6	1354722.JQLS01000008_gene1582	1.447e-75	260.0	COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,46QNV@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS1_k127_510613_10	1122614.JHZF01000011_gene1856	1.782e-36	138.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,2PEGS@252301|Oceanicola	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS1_k127_510613_0	1288298.rosmuc_01460	1.022e-203	637.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2TR53@28211|Alphaproteobacteria,46PB8@74030|Roseovarius	28211|Alphaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS1_k127_510613_2	351016.RAZWK3B_16305	3.485e-187	587.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,2P1K8@2433|Roseobacter	28211|Alphaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_510613_8	314264.ROS217_21012	5.057e-57	199.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria,46QW9@74030|Roseovarius	28211|Alphaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_510613_7	391613.RTM1035_08889	1.677e-63	228.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2U9A5@28211|Alphaproteobacteria,46QKB@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, MerR family protein	merR	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_510613_1	391613.RTM1035_08894	2.421e-203	637.0	COG0717@1|root,COG0717@2|Bacteria,1MVDH@1224|Proteobacteria,2TR5U@28211|Alphaproteobacteria,46PTH@74030|Roseovarius	28211|Alphaproteobacteria	F	2'-deoxycytidine 5'-triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
CMS1_k127_510613_3	766499.C357_19581	1.119e-111	368.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2TR5R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS1_k127_5109700_0	1354722.JQLS01000008_gene1188	5.909e-243	753.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2TSXR@28211|Alphaproteobacteria,46QDB@74030|Roseovarius	28211|Alphaproteobacteria	S	Containing von Willebrand factor type A (vWA) domain	MA20_09405	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_5109700_1	314264.ROS217_21517	2.774e-173	547.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria,46PCQ@74030|Roseovarius	28211|Alphaproteobacteria	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	MA20_09415	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS1_k127_5109700_2	314264.ROS217_21512	2.059e-145	468.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,2TWCK@28211|Alphaproteobacteria,46NPW@74030|Roseovarius	28211|Alphaproteobacteria	H	Probable molybdopterin binding domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS1_k127_5109700_4	1354722.JQLS01000008_gene1191	5.472e-93	306.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,46PDG@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_5109700_3	314264.ROS217_21502	2.968e-140	446.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,46ND1@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5119276_3	351016.RAZWK3B_03840	1.971e-170	542.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2TT0R@28211|Alphaproteobacteria,2P0YQ@2433|Roseobacter	28211|Alphaproteobacteria	M	Belongs to the mannose-6-phosphate isomerase type 2 family	cpsB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS1_k127_5119276_1	314271.RB2654_10883	3.117e-235	732.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_5119276_0	391613.RTM1035_15762	0.0	1332.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,46P7I@74030|Roseovarius	28211|Alphaproteobacteria	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS1_k127_5119276_2	351016.RAZWK3B_06277	2.593e-195	614.0	COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria,2P1J2@2433|Roseobacter	28211|Alphaproteobacteria	M	COG2951 Membrane-bound lytic murein transglycosylase B	MA20_44755	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	PG_binding_1,SLT_2
CMS1_k127_5119276_4	1288298.rosmuc_03247	1.511e-143	460.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,2TRZ8@28211|Alphaproteobacteria,46PQ5@74030|Roseovarius	28211|Alphaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CMS1_k127_5119276_5	1288298.rosmuc_03248	3.512e-142	457.0	COG0079@1|root,COG0079@2|Bacteria,1MXDP@1224|Proteobacteria,2TUEC@28211|Alphaproteobacteria,46NGN@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase	cobC	-	-	ko:K02225	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002	-	-	-	Aminotran_1_2
CMS1_k127_512313_9	357804.Ping_2981	1.751e-40	154.0	COG4454@1|root,COG4454@2|Bacteria,1RF4H@1224|Proteobacteria,1SF6G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_512313_7	314264.ROS217_05189	4.826e-62	215.0	2DWFS@1|root,32V1J@2|Bacteria,1MZ9A@1224|Proteobacteria,2UDME@28211|Alphaproteobacteria,46R2R@74030|Roseovarius	28211|Alphaproteobacteria	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
CMS1_k127_512313_10	388401.RB2150_04488	6.373e-37	142.0	2DBV6@1|root,32TY6@2|Bacteria,1N0TC@1224|Proteobacteria,2UCAJ@28211|Alphaproteobacteria,3ZHXA@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
CMS1_k127_512313_6	1354722.JQLS01000008_gene2641	3.235e-119	385.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,46QCF@74030|Roseovarius	28211|Alphaproteobacteria	S	Nitrile hydratase, alpha chain	nthA	-	4.2.1.84	ko:K01721,ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
CMS1_k127_512313_3	1354722.JQLS01000008_gene2642	7.407e-183	575.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria,46QJ0@74030|Roseovarius	28211|Alphaproteobacteria	M	COG1560 Lauroyl myristoyl acyltransferase	msbB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS1_k127_512313_2	1288298.rosmuc_02673	2.571e-183	575.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,46N9M@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0408 Coproporphyrinogen III oxidase	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS1_k127_512313_5	314264.ROS217_05269	5.567e-146	465.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2TUA2@28211|Alphaproteobacteria,46P04@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	bacC	-	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_512313_4	314264.ROS217_05264	1.334e-155	496.0	COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,2TSBA@28211|Alphaproteobacteria,46NQ6@74030|Roseovarius	28211|Alphaproteobacteria	J	COG2813 16S RNA G1207 methylase RsmC	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
CMS1_k127_512313_8	314264.ROS217_05259	1.521e-58	207.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,46QV8@74030|Roseovarius	28211|Alphaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS1_k127_512313_0	1354722.JQLS01000008_gene138	1.322e-200	631.0	COG0500@1|root,COG2226@2|Bacteria,1QWA7@1224|Proteobacteria,2TWUC@28211|Alphaproteobacteria,46S4E@74030|Roseovarius	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_31
CMS1_k127_512313_1	1354722.JQLS01000008_gene139	2.208e-188	595.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2TVI7@28211|Alphaproteobacteria,46Q44@74030|Roseovarius	28211|Alphaproteobacteria	M	protein involved in outer membrane biogenesis	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CMS1_k127_5154436_3	1288298.rosmuc_03099	1.785e-29	121.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2TTF9@28211|Alphaproteobacteria,46P3V@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS1_k127_5154436_1	1288298.rosmuc_03100	5.461e-114	370.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2U6ZC@28211|Alphaproteobacteria,46NYW@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_5154436_2	1300350.DSW25_16755	1.097e-94	325.0	COG4782@1|root,COG4782@2|Bacteria,1PSSC@1224|Proteobacteria,2UR7R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
CMS1_k127_5154436_0	1354722.JQLS01000008_gene603	1.664e-260	806.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,46P9J@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	chvD	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_5160185_3	391624.OIHEL45_12460	6.333e-17	83.0	2CHPT@1|root,32YYG@2|Bacteria,1N6R5@1224|Proteobacteria,2UFC7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5160185_0	1354722.JQLS01000008_gene1704	4.557e-166	530.0	COG0583@1|root,COG0583@2|Bacteria,1MXC9@1224|Proteobacteria,2TTTY@28211|Alphaproteobacteria,46NGE@74030|Roseovarius	28211|Alphaproteobacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5160185_2	1354722.JQLS01000008_gene1703	2.754e-88	299.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,46RES@74030|Roseovarius	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS1_k127_5160185_1	1288298.rosmuc_03576	6.504e-151	481.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,46P5T@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5160185_4	89187.ISM_16215	2.045e-08	55.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,46NIT@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS1_k127_5183295_0	391613.RTM1035_05565	2.502e-270	841.0	COG0265@1|root,COG3409@1|root,COG0265@2|Bacteria,COG3409@2|Bacteria,1MV63@1224|Proteobacteria,2TU13@28211|Alphaproteobacteria,46Q96@74030|Roseovarius	28211|Alphaproteobacteria	MO	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SPOR,Trypsin_2
CMS1_k127_5183295_1	391613.RTM1035_05570	1.426e-152	482.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2TS2N@28211|Alphaproteobacteria,46Q1I@74030|Roseovarius	28211|Alphaproteobacteria	J	glycyl-tRNA synthetase alpha	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
CMS1_k127_5183594_1	1354722.JQLS01000008_gene2130	4.186e-53	188.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria,46NIW@74030|Roseovarius	28211|Alphaproteobacteria	S	Predicted permease YjgP/YjgQ family	MA20_28210	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_5183594_0	314270.RB2083_86	2.405e-211	666.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,3ZGTR@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS1_k127_5183594_2	1354722.JQLS01000008_gene2132	1.284e-52	186.0	COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,46QJW@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA polymerase III, chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
CMS1_k127_5193734_3	89187.ISM_02395	3.244e-68	233.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2U95Q@28211|Alphaproteobacteria,46P00@74030|Roseovarius	28211|Alphaproteobacteria	H	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CMS1_k127_5193734_4	1354722.JQLS01000008_gene3610	3.934e-58	205.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2UBSV@28211|Alphaproteobacteria,46QP7@74030|Roseovarius	28211|Alphaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS1_k127_5193734_0	1354722.JQLS01000008_gene3609	3.199e-243	755.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,46NIN@74030|Roseovarius	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	MA20_40450	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS1_k127_5193734_2	314264.ROS217_09115	1.364e-165	530.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TSX9@28211|Alphaproteobacteria,46NYX@74030|Roseovarius	28211|Alphaproteobacteria	BQ	Including yeast histone deacetylase and acetoin utilization protein	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
CMS1_k127_5193734_1	314264.ROS217_09120	5.266e-189	597.0	COG2223@1|root,COG2223@2|Bacteria,1QU99@1224|Proteobacteria,2TW9H@28211|Alphaproteobacteria,46P4Z@74030|Roseovarius	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5193734_5	1123360.thalar_03220	9.18e-06	54.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_5203188_0	1354722.JQLS01000008_gene2924	1.536e-79	271.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,46Q7F@74030|Roseovarius	28211|Alphaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD,FlgD_ig
CMS1_k127_5203188_2	314264.ROS217_11871	1.396e-24	117.0	COG3144@1|root,COG3144@2|Bacteria,1N882@1224|Proteobacteria,2UG0B@28211|Alphaproteobacteria,46R8H@74030|Roseovarius	28211|Alphaproteobacteria	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
CMS1_k127_5203188_3	1123247.AUIJ01000011_gene549	2.209e-14	80.0	COG3951@1|root,COG3951@2|Bacteria,1N8ET@1224|Proteobacteria,2UF4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Flagellar protein FlgJ	flgJ	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
CMS1_k127_5203188_1	391613.RTM1035_20476	5.086e-33	131.0	2E6XZ@1|root,331HA@2|Bacteria,1NB2S@1224|Proteobacteria,2UGXP@28211|Alphaproteobacteria,46R5A@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
CMS1_k127_5203188_4	1300350.DSW25_01035	1.962e-07	52.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2TTW2@28211|Alphaproteobacteria,3ZVX1@60136|Sulfitobacter	28211|Alphaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS1_k127_5219771_3	391613.RTM1035_08109	1.145e-105	345.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,46NY7@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS1_k127_5219771_2	1288298.rosmuc_01617	8.284e-184	580.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,46Q87@74030|Roseovarius	28211|Alphaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
CMS1_k127_5219771_1	314264.ROS217_20227	1.166e-188	592.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2TS7I@28211|Alphaproteobacteria,46NGG@74030|Roseovarius	28211|Alphaproteobacteria	K	COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K21826	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
CMS1_k127_5219771_0	314264.ROS217_20232	2.953e-278	859.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria,46P86@74030|Roseovarius	28211|Alphaproteobacteria	E	COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	aroF	GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
CMS1_k127_5219771_4	1354722.JQLS01000008_gene1373	8.312e-71	245.0	COG5388@1|root,COG5388@2|Bacteria,1RCVG@1224|Proteobacteria,2U2IX@28211|Alphaproteobacteria,46NJX@74030|Roseovarius	28211|Alphaproteobacteria	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_5
CMS1_k127_5219771_5	1288298.rosmuc_01613	6.385e-10	63.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2TS81@28211|Alphaproteobacteria,46PWM@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS1_k127_5237827_0	1354722.JQLS01000008_gene2884	2.919e-234	728.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,46NU1@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1062 Zn-dependent alcohol dehydrogenases, class III	adhC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0008150,GO:0008152,GO:0015945,GO:0034308,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:1901615	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5237827_2	1288298.rosmuc_00852	3.292e-171	539.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTDF@28211|Alphaproteobacteria,46NHM@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	yghU	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
CMS1_k127_5237827_3	1305735.JAFT01000005_gene1762	1.271e-116	379.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2TRE6@28211|Alphaproteobacteria,2PDKI@252301|Oceanicola	28211|Alphaproteobacteria	S	OST-HTH/LOTUS domain	MA20_15040	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS1_k127_5237827_1	391613.RTM1035_19966	3.733e-176	569.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2TR7D@28211|Alphaproteobacteria,46NRD@74030|Roseovarius	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_5237827_4	1354722.JQLS01000008_gene3645	3.307e-90	299.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,46Q5D@74030|Roseovarius	28211|Alphaproteobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS1_k127_5237827_5	1354722.JQLS01000008_gene3646	4.72e-13	69.0	COG2755@1|root,COG2755@2|Bacteria,1RC2Z@1224|Proteobacteria,2U5PG@28211|Alphaproteobacteria,46P4A@74030|Roseovarius	28211|Alphaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_5248048_1	1288298.rosmuc_00491	3.234e-189	593.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46QGK@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_5248048_5	391613.RTM1035_19936	1.903e-127	411.0	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2TUQ3@28211|Alphaproteobacteria,46PDW@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0657 Esterase lipase	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Abhydrolase_6
CMS1_k127_5248048_0	391613.RTM1035_19941	1.823e-232	722.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TRA4@28211|Alphaproteobacteria,46NSG@74030|Roseovarius	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	MA20_42180	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5248048_4	1288298.rosmuc_00494	2.68e-147	471.0	COG2267@1|root,COG2267@2|Bacteria,1R3WF@1224|Proteobacteria,2U0N0@28211|Alphaproteobacteria,46NNH@74030|Roseovarius	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
CMS1_k127_5248048_3	391613.RTM1035_19951	2.577e-170	538.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,46PV0@74030|Roseovarius	28211|Alphaproteobacteria	E	Ornithine cyclodeaminase mu-crystallin family protein	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS1_k127_5248048_2	314264.ROS217_08945	9.208e-176	557.0	COG0697@1|root,COG0697@2|Bacteria,1MXPW@1224|Proteobacteria,2U1CD@28211|Alphaproteobacteria,46Q1E@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
CMS1_k127_525344_0	391613.RTM1035_03525	5.715e-201	628.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria,46P0Q@74030|Roseovarius	28211|Alphaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_525344_1	766499.C357_17870	1.335e-18	85.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2VFNY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
CMS1_k127_525344_2	1500304.JQKY01000027_gene1298	0.0005064	46.0	COG1525@1|root,COG1525@2|Bacteria,1PRMI@1224|Proteobacteria,2UA9S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
CMS1_k127_526065_8	1449351.RISW2_12225	7.325e-26	110.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,2UR2U@28211|Alphaproteobacteria,4KNMW@93682|Roseivivax	28211|Alphaproteobacteria	IQ	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
CMS1_k127_526065_2	1354722.JQLS01000008_gene215	2.502e-229	721.0	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,2TTZ8@28211|Alphaproteobacteria,46NWY@74030|Roseovarius	28211|Alphaproteobacteria	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
CMS1_k127_526065_4	1288298.rosmuc_03880	3.792e-119	389.0	COG1215@1|root,COG1215@2|Bacteria,1N51K@1224|Proteobacteria,2TRPU@28211|Alphaproteobacteria,46NP1@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_526065_3	314264.ROS217_05039	8.956e-195	621.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria,46PY2@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_526065_0	391613.RTM1035_03240	0.0	1308.0	COG1028@1|root,COG1028@2|Bacteria,1MWC8@1224|Proteobacteria,2TS15@28211|Alphaproteobacteria,46NTT@74030|Roseovarius	28211|Alphaproteobacteria	IQ	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_526065_6	391613.RTM1035_03245	3.127e-94	311.0	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,2U992@28211|Alphaproteobacteria,46PFX@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_526065_5	89187.ISM_02250	1.874e-116	377.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,46NI0@74030|Roseovarius	28211|Alphaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS1_k127_526065_7	1354722.JQLS01000008_gene221	3.744e-79	266.0	2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria,46QG8@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF3576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3576
CMS1_k127_526065_1	314264.ROS217_13931	2.243e-233	729.0	COG0438@1|root,COG0438@2|Bacteria,1NJ19@1224|Proteobacteria,2TRT4@28211|Alphaproteobacteria,46P6Z@74030|Roseovarius	28211|Alphaproteobacteria	M	Gkycosyl transferase family 4 group	expC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_3,Glycos_transf_1
CMS1_k127_5278184_7	314264.ROS217_09832	9.585e-30	117.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2TUXV@28211|Alphaproteobacteria,46NMQ@74030|Roseovarius	28211|Alphaproteobacteria	S	ErfK YbiS YcfS YnhG family protein Tat domain protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
CMS1_k127_5278184_8	1288298.rosmuc_00158	6.024e-25	106.0	2DP38@1|root,330C2@2|Bacteria,1NB3K@1224|Proteobacteria,2UHE3@28211|Alphaproteobacteria,46R9A@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5278184_0	391613.RTM1035_18380	1.261e-215	671.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,46PKA@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS1_k127_5278184_3	1288298.rosmuc_00156	1.646e-132	430.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,46PWF@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	bioC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_5278184_4	1354722.JQLS01000008_gene3476	1.953e-117	387.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,46PH5@74030|Roseovarius	28211|Alphaproteobacteria	S	Competence protein F	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS1_k127_5278184_6	314264.ROS217_09857	3.504e-43	158.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,46R08@74030|Roseovarius	28211|Alphaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
CMS1_k127_5278184_1	1354722.JQLS01000008_gene3474	1.283e-153	488.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,46PAQ@74030|Roseovarius	28211|Alphaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.77	ko:K01459,ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS1_k127_5278184_5	1354722.JQLS01000008_gene3473	1.302e-82	275.0	COG1846@1|root,COG1846@2|Bacteria,1RD9U@1224|Proteobacteria,2U7NF@28211|Alphaproteobacteria,46PCC@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_5278184_2	1288298.rosmuc_00151	3.945e-142	452.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,46P2X@74030|Roseovarius	28211|Alphaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_5281386_3	391613.RTM1035_17622	4.569e-120	388.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,46NEY@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator	iclR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
CMS1_k127_5281386_0	1354722.JQLS01000008_gene3731	1.235e-227	710.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,46P1G@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	sgaA	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_5281386_2	314264.ROS217_08264	4.64e-191	600.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,46QK3@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1171 Threonine dehydratase	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_5281386_1	391593.RCCS2_06444	8.991e-201	628.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria,2P2DA@2433|Roseobacter	28211|Alphaproteobacteria	E	amino acid aldolase or racemase	dhaa	-	4.1.3.41	ko:K18425	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS1_k127_5283086_2	391613.RTM1035_17765	2.755e-214	666.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,46PQI@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
CMS1_k127_5283086_1	314264.ROS217_11096	2.138e-235	729.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2TRJ3@28211|Alphaproteobacteria,46P4M@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0687 Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
CMS1_k127_5283086_0	314264.ROS217_11101	1.122e-301	931.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2TTJ6@28211|Alphaproteobacteria,46NRZ@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1176 ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
CMS1_k127_5283086_3	1354722.JQLS01000008_gene3076	1.507e-71	243.0	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2TS3C@28211|Alphaproteobacteria,46NAA@74030|Roseovarius	28211|Alphaproteobacteria	P	ABC-type spermidine putrescine transport system, permease component	potC	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
CMS1_k127_5283715_1	1288298.rosmuc_02811	2.998e-128	413.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,2TV26@28211|Alphaproteobacteria,46NSA@74030|Roseovarius	28211|Alphaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS1_k127_5283715_0	314264.ROS217_04630	5.055e-145	462.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria,46PST@74030|Roseovarius	28211|Alphaproteobacteria	J	COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_5283715_2	1288298.rosmuc_01694	1.026e-72	261.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,46QN4@74030|Roseovarius	28211|Alphaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.3,3.5.4.33	ko:K01485,ko:K01487,ko:K11991	ko00230,ko00240,ko00330,ko01100,map00230,map00240,map00330,map01100	-	R00974,R01411,R01676,R02922,R10223	RC00074,RC00204,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
CMS1_k127_5283715_3	1288298.rosmuc_01693	7.378e-39	145.0	COG0583@1|root,COG0583@2|Bacteria,1MXDT@1224|Proteobacteria,2TRY1@28211|Alphaproteobacteria,46NMX@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional Regulator, LysR family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5289152_6	766499.C357_11429	3.031e-23	98.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS1_k127_5289152_1	1354722.JQLS01000008_gene1793	3.157e-191	606.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria,46RSV@74030|Roseovarius	28211|Alphaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS1_k127_5289152_2	1354722.JQLS01000008_gene1794	5.7e-159	510.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2TQJM@28211|Alphaproteobacteria,46RQD@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5289152_3	1354722.JQLS01000008_gene1795	3.476e-88	297.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,46P5Q@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1223)	MA20_43790	-	-	-	-	-	-	-	-	-	-	-	DUF1223
CMS1_k127_5289152_0	1354722.JQLS01000008_gene1796	0.0	1726.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,46NA4@74030|Roseovarius	28211|Alphaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_5289152_5	272942.RCAP_rcc02152	6.946e-26	110.0	COG2314@1|root,COG2314@2|Bacteria,1N8Y8@1224|Proteobacteria,2UFKT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
CMS1_k127_5289152_7	1354722.JQLS01000008_gene1797	1.153e-05	49.0	2A4GF@1|root,30T2K@2|Bacteria,1PR37@1224|Proteobacteria,2V3EM@28211|Alphaproteobacteria,46RC6@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5289152_4	1288298.rosmuc_03311	1.975e-67	229.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,46NGH@74030|Roseovarius	28211|Alphaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	ccmG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_5299280_4	1354722.JQLS01000008_gene397	3.111e-16	83.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2TU06@28211|Alphaproteobacteria,46PH6@74030|Roseovarius	28211|Alphaproteobacteria	S	component of anaerobic dehydrogenases	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del,YdaS_antitoxin
CMS1_k127_5299280_3	314264.ROS217_14406	9.809e-63	222.0	2DP0X@1|root,3302S@2|Bacteria,1RIRD@1224|Proteobacteria,2UA7P@28211|Alphaproteobacteria,46QPS@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3306
CMS1_k127_5299280_2	1354722.JQLS01000008_gene395	8.608e-80	271.0	COG0746@1|root,COG0746@2|Bacteria,1RB53@1224|Proteobacteria,2TUXF@28211|Alphaproteobacteria,46QMV@74030|Roseovarius	28211|Alphaproteobacteria	H	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
CMS1_k127_5299280_0	391613.RTM1035_03355	0.0	1075.0	COG1036@1|root,COG1148@1|root,COG1036@2|Bacteria,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2TWJ4@28211|Alphaproteobacteria,46NFB@74030|Roseovarius	28211|Alphaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
CMS1_k127_5299280_1	1288298.rosmuc_02447	4.59e-100	330.0	COG2010@1|root,COG2010@2|Bacteria,1RB6G@1224|Proteobacteria,2U5XE@28211|Alphaproteobacteria,46QI7@74030|Roseovarius	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_5301035_5	351016.RAZWK3B_08786	1.948e-55	194.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2TS8M@28211|Alphaproteobacteria,2P10A@2433|Roseobacter	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_5301035_4	1190603.AJYD01000026_gene3261	3.395e-86	294.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RYA3@1236|Gammaproteobacteria,1XWUI@135623|Vibrionales	135623|Vibrionales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_5301035_2	1354722.JQLS01000008_gene3581	1.919e-267	835.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2TRF9@28211|Alphaproteobacteria,46PZS@74030|Roseovarius	28211|Alphaproteobacteria	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
CMS1_k127_5301035_3	1367847.JCM7686_3371	3.894e-114	395.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TVDS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
CMS1_k127_5301035_1	1288298.rosmuc_00355	3.904e-272	844.0	COG1232@1|root,COG1232@2|Bacteria,1Q8M7@1224|Proteobacteria,2UXPJ@28211|Alphaproteobacteria,46QHM@74030|Roseovarius	28211|Alphaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_5301035_0	1354722.JQLS01000008_gene3579	2.336e-281	876.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,46Q32@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS1_k127_5301035_6	314271.RB2654_05612	2.421e-42	164.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL,cNMP_binding
CMS1_k127_5301035_7	314264.ROS217_09265	9.954e-42	158.0	2BGF0@1|root,32ACV@2|Bacteria,1RI61@1224|Proteobacteria,2UIUG@28211|Alphaproteobacteria,46QXC@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
CMS1_k127_5301035_8	246200.SPO1110	9.776e-13	70.0	COG0583@1|root,COG0583@2|Bacteria,1QU1H@1224|Proteobacteria,2U0TE@28211|Alphaproteobacteria,4ND30@97050|Ruegeria	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_53021_5	1354722.JQLS01000008_gene1407	6.469e-112	364.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2TTQS@28211|Alphaproteobacteria,46QDD@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	MA20_27940	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_53021_2	391613.RTM1035_08314	1.624e-153	488.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,46NKR@74030|Roseovarius	28211|Alphaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS1_k127_53021_3	1354722.JQLS01000008_gene1409	4.305e-128	411.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,46QDQ@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_53021_0	1288298.rosmuc_01575	2.571e-194	611.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria,46PGA@74030|Roseovarius	28211|Alphaproteobacteria	DM	COG0739 Membrane proteins related to metalloendopeptidases	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
CMS1_k127_53021_6	1354722.JQLS01000008_gene1411	5.482e-13	72.0	2EQBZ@1|root,33HY3@2|Bacteria,1NHZI@1224|Proteobacteria,2UJTQ@28211|Alphaproteobacteria,46R9J@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_53021_1	1288298.rosmuc_01573	1.075e-182	577.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,2TU5N@28211|Alphaproteobacteria,46PPJ@74030|Roseovarius	28211|Alphaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_53021_4	1354722.JQLS01000008_gene1413	2.647e-118	381.0	COG2897@1|root,COG2897@2|Bacteria,1P6SN@1224|Proteobacteria,2TVFJ@28211|Alphaproteobacteria,46PW3@74030|Roseovarius	28211|Alphaproteobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_5303038_8	292414.TM1040_3781	8.055e-71	245.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	methionine sulfoxide reductase	msrB1	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS1_k127_5303038_5	391589.RGAI101_2110	7.328e-98	322.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2P35Q@2433|Roseobacter	28211|Alphaproteobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_5303038_9	292414.TM1040_3783	3.198e-64	228.0	COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,2UF3V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	RskA
CMS1_k127_5303038_7	292414.TM1040_3784	5.947e-84	285.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2V99Q@28211|Alphaproteobacteria,4NDKY@97050|Ruegeria	28211|Alphaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5303038_11	411684.HPDFL43_10526	7.893e-28	116.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,2TQYR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
CMS1_k127_5303038_6	351016.RAZWK3B_19281	7.896e-94	311.0	COG1309@1|root,COG1309@2|Bacteria,1R59A@1224|Proteobacteria,2U08S@28211|Alphaproteobacteria,2P37Z@2433|Roseobacter	28211|Alphaproteobacteria	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_5303038_0	351016.RAZWK3B_19271	0.0	1304.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,2P1VD@2433|Roseobacter	28211|Alphaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	stcD	-	-	ko:K21833	-	-	-	-	ko00000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox_2
CMS1_k127_5303038_1	246200.SPO0164	0.0	1029.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,4NBN2@97050|Ruegeria	28211|Alphaproteobacteria	C	hmm pf00724	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS1_k127_5303038_3	1208323.B30_02970	8.416e-230	717.0	COG0477@1|root,COG2814@2|Bacteria,1MX4G@1224|Proteobacteria,2TTT7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5303038_12	1208323.B30_02975	1.141e-19	89.0	COG1937@1|root,COG1937@2|Bacteria	2|Bacteria	S	negative regulation of transcription, DNA-templated	csoR	-	-	ko:K07807,ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
CMS1_k127_5303038_10	391589.RGAI101_4243	1.451e-47	184.0	COG2931@1|root,COG2931@2|Bacteria,1N4XC@1224|Proteobacteria,2UC73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_5303038_14	1415756.JQMY01000001_gene1043	1.455e-09	62.0	COG4256@1|root,COG4256@2|Bacteria,1Q2RT@1224|Proteobacteria,2V9ZE@28211|Alphaproteobacteria,2PFSH@252301|Oceanicola	28211|Alphaproteobacteria	P	Hemin uptake protein hemP	-	-	-	-	-	-	-	-	-	-	-	-	hemP
CMS1_k127_5303038_2	52598.EE36_10454	1.959e-293	923.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TTQD@28211|Alphaproteobacteria,3ZWIT@60136|Sulfitobacter	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
CMS1_k127_5303038_4	52598.EE36_10445	3.392e-102	337.0	COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2TRH2@28211|Alphaproteobacteria,3ZWQP@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Prolyl 4-hydroxylase alpha subunit homologues.	MA20_27135	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0033554,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771	1.14.11.2	ko:K00472,ko:K07336	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
CMS1_k127_5303038_13	272942.RCAP_rcc02375	3.937e-18	89.0	COG0811@1|root,COG0811@2|Bacteria,1MXHR@1224|Proteobacteria,2TQNN@28211|Alphaproteobacteria,1FCT6@1060|Rhodobacter	28211|Alphaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_5305160_1	314264.ROS217_18662	2.664e-311	960.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,2TR0V@28211|Alphaproteobacteria,46P3I@74030|Roseovarius	28211|Alphaproteobacteria	H	COG5598 Trimethylamine corrinoid methyltransferase	mttB2	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_5305160_2	1354722.JQLS01000008_gene1707	5.341e-220	689.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2TRJP@28211|Alphaproteobacteria,46Q5B@74030|Roseovarius	28211|Alphaproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS1_k127_5305160_0	351016.RAZWK3B_15648	0.0	1018.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria,2P2H7@2433|Roseobacter	28211|Alphaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS1_k127_5305160_4	1354722.JQLS01000008_gene1710	1.206e-12	71.0	2AJKK@1|root,30IGR@2|Bacteria,1RFE5@1224|Proteobacteria,2U784@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_5305160_3	314264.ROS217_18642	5.277e-142	455.0	COG0697@1|root,COG0697@2|Bacteria,1MV7Y@1224|Proteobacteria,2TUVM@28211|Alphaproteobacteria,46PMS@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_5306841_1	1354722.JQLS01000008_gene2213	2.42e-61	216.0	COG0106@1|root,COG0106@2|Bacteria,1R41G@1224|Proteobacteria,2U0NV@28211|Alphaproteobacteria,46NVM@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	hisA2	GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_5306841_3	391613.RTM1035_10600	5.783e-39	146.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria,46R49@74030|Roseovarius	28211|Alphaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS1_k127_5306841_0	1354722.JQLS01000008_gene1156	5.012e-132	424.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,46QCV@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_5306841_2	1354722.JQLS01000008_gene1155	5.489e-46	168.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,46PX6@74030|Roseovarius	28211|Alphaproteobacteria	I	Acyl-carrier-protein S-malonyltransferase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS1_k127_533371_0	1354722.JQLS01000008_gene627	0.0	1105.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2TS8V@28211|Alphaproteobacteria,46NE5@74030|Roseovarius	28211|Alphaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis	MA20_43810	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_533371_2	1288298.rosmuc_03126	2.636e-145	465.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2U1X2@28211|Alphaproteobacteria,46Q6P@74030|Roseovarius	28211|Alphaproteobacteria	G	and related enzymes of inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_533371_1	1354722.JQLS01000008_gene625	1.98e-152	491.0	COG2267@1|root,COG2771@1|root,COG2267@2|Bacteria,COG2771@2|Bacteria,1QV2F@1224|Proteobacteria,2U8KM@28211|Alphaproteobacteria,46S40@74030|Roseovarius	28211|Alphaproteobacteria	IK	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,GerE,Hydrolase_4
CMS1_k127_5335536_2	351016.RAZWK3B_03785	8.02e-150	475.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2P0ZR@2433|Roseobacter	28211|Alphaproteobacteria	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS1_k127_5335536_4	391613.RTM1035_20111	5.351e-76	258.0	COG0741@1|root,COG0741@2|Bacteria,1N08U@1224|Proteobacteria,2U82R@28211|Alphaproteobacteria,46QHN@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_5335536_1	391613.RTM1035_20116	2.528e-150	483.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2TRDY@28211|Alphaproteobacteria,46NIH@74030|Roseovarius	28211|Alphaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_5335536_5	1288298.rosmuc_00589	2.086e-51	187.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,2U9EH@28211|Alphaproteobacteria,46R0Z@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
CMS1_k127_5335536_3	1417296.U879_08175	1.584e-91	310.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TSYF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_5335536_0	571166.KI421509_gene1863	6.909e-175	557.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS1_k127_5338138_3	391613.RTM1035_09419	4.079e-155	493.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,46P9C@74030|Roseovarius	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	nahG	-	1.14.13.1	ko:K00480	ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
CMS1_k127_5338138_2	314264.ROS217_21067	8.164e-157	496.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,46NKH@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0708 Exonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_5338138_4	1288298.rosmuc_01446	1.96e-57	201.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,46QX9@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the HesB IscA family	erpA	-	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS1_k127_5338138_1	1354722.JQLS01000008_gene1596	3.779e-207	649.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,46QAI@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS1_k127_5338138_0	351016.RAZWK3B_16360	3.625e-274	854.0	COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,2TW3I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0025 NhaP-type Na H and K H antiporters	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_5338138_5	1354722.JQLS01000008_gene1595	3.004e-40	156.0	2ERI9@1|root,33J3S@2|Bacteria,1NPQI@1224|Proteobacteria,2UKT1@28211|Alphaproteobacteria,46QJT@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5338138_6	1423144.Gal_02375	5.937e-08	54.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,34DYK@302485|Phaeobacter	28211|Alphaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS1_k127_5339159_4	314264.ROS217_08289	2.547e-53	190.0	COG4665@1|root,COG4665@2|Bacteria,1RDYM@1224|Proteobacteria,2TVMY@28211|Alphaproteobacteria,46QGY@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_5339159_3	314264.ROS217_08284	3.158e-117	382.0	COG3931@1|root,COG3931@2|Bacteria,1R6N8@1224|Proteobacteria,2U5EQ@28211|Alphaproteobacteria,46P07@74030|Roseovarius	28211|Alphaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS1_k127_5339159_2	314264.ROS217_08279	5.193e-167	529.0	COG1737@1|root,COG1737@2|Bacteria,1N3YS@1224|Proteobacteria,2TTJD@28211|Alphaproteobacteria,46P5U@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1737 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
CMS1_k127_5339159_1	439496.RBY4I_40	1.016e-186	588.0	COG0665@1|root,COG0665@2|Bacteria,1MVG3@1224|Proteobacteria,2TRYR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_5339159_5	89187.ISM_01035	4.994e-26	111.0	COG3383@1|root,COG3383@2|Bacteria,1QUPZ@1224|Proteobacteria,2TWJY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
CMS1_k127_5339159_0	89187.ISM_01030	4.885e-199	634.0	COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,2TVYN@28211|Alphaproteobacteria,46RWZ@74030|Roseovarius	28211|Alphaproteobacteria	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
CMS1_k127_5339159_6	384765.SIAM614_18839	1.722e-11	64.0	2B2MT@1|root,31V7A@2|Bacteria,1MYYT@1224|Proteobacteria,2UBHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5340374_1	1458357.BG58_24900	1.479e-14	78.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2VWKS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pfam cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_5340374_0	1187851.A33M_1830	7.895e-32	130.0	COG2010@1|root,COG2010@2|Bacteria,1NDHN@1224|Proteobacteria,2UBRQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
CMS1_k127_5340374_2	857087.Metme_0815	6.319e-11	66.0	293CN@1|root,2ZQV6@2|Bacteria,1RDZB@1224|Proteobacteria,1T0P9@1236|Gammaproteobacteria,1XE1D@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_535136_0	314264.ROS217_04770	2.552e-200	627.0	COG2931@1|root,COG2931@2|Bacteria,1R4WR@1224|Proteobacteria,2U41T@28211|Alphaproteobacteria,46Q1P@74030|Roseovarius	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_535136_2	351016.RAZWK3B_07514	3.095e-144	460.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,1MWYQ@1224|Proteobacteria,2TU1U@28211|Alphaproteobacteria,2P1T0@2433|Roseobacter	28211|Alphaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,LMWPc
CMS1_k127_535136_1	351016.RAZWK3B_07519	1.626e-198	624.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TU32@28211|Alphaproteobacteria,2P2IS@2433|Roseobacter	28211|Alphaproteobacteria	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap3	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_535136_3	1449350.OCH239_15275	1.783e-06	52.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,2TT4B@28211|Alphaproteobacteria,4KK7V@93682|Roseivivax	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5364023_5	351016.RAZWK3B_03805	5.128e-122	392.0	COG0683@1|root,COG0683@2|Bacteria,1MWYP@1224|Proteobacteria,2TTAM@28211|Alphaproteobacteria,2P47K@2433|Roseobacter	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_5364023_8	1354722.JQLS01000008_gene3617	1.488e-98	328.0	COG4238@1|root,COG4238@2|Bacteria,1RDE3@1224|Proteobacteria,2U7FF@28211|Alphaproteobacteria,46P9E@74030|Roseovarius	28211|Alphaproteobacteria	M	major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5364023_2	391613.RTM1035_19826	4.923e-172	543.0	COG0559@1|root,COG0559@2|Bacteria,1PHIJ@1224|Proteobacteria,2TUKF@28211|Alphaproteobacteria,46PFJ@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_5364023_3	1354722.JQLS01000008_gene3615	1.859e-162	524.0	COG4177@1|root,COG4177@2|Bacteria,1Q5UA@1224|Proteobacteria,2TT00@28211|Alphaproteobacteria,46PYD@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_5364023_7	1288298.rosmuc_00467	1.102e-106	355.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSWS@28211|Alphaproteobacteria,46PRY@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_5364023_6	89187.ISM_05980	8.702e-120	389.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2TSRT@28211|Alphaproteobacteria,46NHU@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_5364023_9	314264.ROS217_08720	5.388e-72	245.0	COG0454@1|root,COG0456@2|Bacteria,1MZUT@1224|Proteobacteria,2UC9I@28211|Alphaproteobacteria,46QNR@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5364023_0	391613.RTM1035_19681	0.0	1206.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,46P0C@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	mutB	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS1_k127_5364023_1	314264.ROS217_08700	1.908e-237	743.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2TSDK@28211|Alphaproteobacteria,46PQQ@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_5364023_4	1469613.JT55_14575	1.97e-156	496.0	COG0604@1|root,COG0604@2|Bacteria,1MXIK@1224|Proteobacteria,2TQPR@28211|Alphaproteobacteria,3FCIP@34008|Rhodovulum	28211|Alphaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	ccrA	-	1.1.1.1,1.3.1.85	ko:K00001,ko:K14446	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	M00373	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5367182_0	351016.RAZWK3B_01940	3.434e-251	779.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,2P2DN@2433|Roseobacter	28211|Alphaproteobacteria	L	COG0514 Superfamily II DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS1_k127_5367182_2	1123247.AUIJ01000023_gene795	6.997e-121	392.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2TS11@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
CMS1_k127_5367182_1	1354722.JQLS01000008_gene3669	5.575e-246	769.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWK9@28211|Alphaproteobacteria,46NRU@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
CMS1_k127_539168_6	391619.PGA1_c00590	9.729e-09	57.0	COG1605@1|root,COG1605@2|Bacteria,1MZTQ@1224|Proteobacteria,2UCMC@28211|Alphaproteobacteria,34FSG@302485|Phaeobacter	28211|Alphaproteobacteria	E	Chorismate mutase type II	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
CMS1_k127_539168_2	351016.RAZWK3B_05447	3.745e-116	375.0	COG1670@1|root,COG1670@2|Bacteria,1PY0X@1224|Proteobacteria,2VEXD@28211|Alphaproteobacteria,2P1H6@2433|Roseobacter	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_539168_3	1354722.JQLS01000008_gene3770	4.539e-105	345.0	COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,2U851@28211|Alphaproteobacteria,46NUY@74030|Roseovarius	28211|Alphaproteobacteria	J	Including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS1_k127_539168_0	1288298.rosmuc_00876	3.582e-273	848.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,46PR0@74030|Roseovarius	28211|Alphaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS1_k127_539168_5	1121033.AUCF01000018_gene5834	3.318e-21	100.0	2E43S@1|root,32Z03@2|Bacteria,1NB33@1224|Proteobacteria,2UUD0@28211|Alphaproteobacteria,2JXKU@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_539168_1	314264.ROS217_08454	6.613e-167	527.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,46Q05@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_539168_4	1354722.JQLS01000008_gene3766	6.295e-28	117.0	COG0697@1|root,COG0697@2|Bacteria,1P3V0@1224|Proteobacteria,2TQJK@28211|Alphaproteobacteria,46Q77@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_5395807_4	1288298.rosmuc_01419	1.636e-111	367.0	COG3473@1|root,COG3473@2|Bacteria,1RB05@1224|Proteobacteria,2U5DB@28211|Alphaproteobacteria,46NVU@74030|Roseovarius	28211|Alphaproteobacteria	Q	Asp Glu Hydantoin racemase family protein	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
CMS1_k127_5395807_1	1354722.JQLS01000008_gene1294	1.76e-203	637.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2TS4G@28211|Alphaproteobacteria,46PBW@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS1_k127_5395807_0	391593.RCCS2_17446	5.61e-233	736.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria,2P1N1@2433|Roseobacter	28211|Alphaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS1_k127_5395807_3	1123360.thalar_01397	1.704e-173	549.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2TSVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0798 Arsenite efflux pump ACR3 and related permeases	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS1_k127_5395807_2	1354722.JQLS01000008_gene1292	6.369e-200	627.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,46QB2@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CMS1_k127_5395807_5	314264.ROS217_19492	5.923e-84	282.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,46PBA@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS1_k127_5395807_6	314264.ROS217_19487	1.582e-09	59.0	2EHRS@1|root,33BHI@2|Bacteria,1NGHV@1224|Proteobacteria,2UK22@28211|Alphaproteobacteria,46RAT@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5396710_1	351016.RAZWK3B_20186	2.133e-90	298.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,2P0XK@2433|Roseobacter	28211|Alphaproteobacteria	S	Polyphosphate kinase 2	ppk2	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
CMS1_k127_5396710_0	1354722.JQLS01000008_gene1125	4.682e-225	704.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,46NTQ@74030|Roseovarius	28211|Alphaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS1_k127_5396710_2	1354722.JQLS01000008_gene1776	1.829e-70	239.0	29EMG@1|root,301JE@2|Bacteria,1RD6J@1224|Proteobacteria,2U79C@28211|Alphaproteobacteria,46QP9@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5396710_3	388401.RB2150_05628	1.534e-13	70.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,3ZGM6@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5412153_1	1354722.JQLS01000008_gene707	5.564e-138	442.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,46NVH@74030|Roseovarius	28211|Alphaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS1_k127_5412153_0	1354722.JQLS01000008_gene708	1.524e-275	850.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,46NKC@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS1_k127_5412153_3	1469613.JT55_02400	1.109e-12	71.0	2EJUN@1|root,33DJA@2|Bacteria,1NGAS@1224|Proteobacteria,2UNJC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5412153_2	314264.ROS217_16805	2.562e-22	97.0	2AJD4@1|root,319YK@2|Bacteria,1Q4G2@1224|Proteobacteria,2VAY0@28211|Alphaproteobacteria,46R1P@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5437852_0	467661.RKLH11_2553	8.736e-182	576.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,3ZGGV@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_5437852_1	991905.SL003B_0381	1.59e-23	102.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,4BQ41@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_5459891_0	1354722.JQLS01000008_gene803	3.254e-129	419.0	28K40@1|root,2Z9T4@2|Bacteria,1R3V0@1224|Proteobacteria,2U1QP@28211|Alphaproteobacteria,46PPF@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5459891_1	314264.ROS217_23562	1.748e-69	238.0	2CH3G@1|root,32S56@2|Bacteria,1N1AC@1224|Proteobacteria,2UCDP@28211|Alphaproteobacteria,46QPH@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4174)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4174
CMS1_k127_5459891_2	1354722.JQLS01000008_gene801	5.714e-49	180.0	28MJU@1|root,32Z7K@2|Bacteria,1N90B@1224|Proteobacteria,2UFN2@28211|Alphaproteobacteria,46QN6@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5459891_3	1121033.AUCF01000040_gene818	7.545e-10	60.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,2TVMP@28211|Alphaproteobacteria,2JR9B@204441|Rhodospirillales	204441|Rhodospirillales	V	Mrr N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_N,Mrr_cat
CMS1_k127_5462349_3	314264.ROS217_08059	3.278e-176	557.0	COG1173@1|root,COG1173@2|Bacteria,1MU0P@1224|Proteobacteria,2TSX5@28211|Alphaproteobacteria,46PIP@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5462349_4	391613.RTM1035_19061	4.147e-173	546.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSIY@28211|Alphaproteobacteria,46NPH@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5462349_0	89187.ISM_01645	6.369e-310	953.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2U0CD@28211|Alphaproteobacteria,46Q8B@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5462349_1	314264.ROS217_08074	7.345e-257	794.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2TQVF@28211|Alphaproteobacteria,46N9C@74030|Roseovarius	28211|Alphaproteobacteria	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS1_k127_5462349_5	391626.OAN307_c43910	8.751e-76	255.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS1_k127_5462349_2	1354722.JQLS01000008_gene3342	5.105e-217	674.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria,46QAQ@74030|Roseovarius	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_5462349_6	314264.ROS217_08094	4.057e-72	244.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,46QQ7@74030|Roseovarius	28211|Alphaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS1_k127_5462349_7	1354722.JQLS01000008_gene3344	4.858e-69	236.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,46QU3@74030|Roseovarius	28211|Alphaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS1_k127_5462349_8	272943.RSP_1736	3.427e-08	54.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,1FB52@1060|Rhodobacter	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_5466108_0	391613.RTM1035_09229	8.253e-147	470.0	COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,2TR9Y@28211|Alphaproteobacteria,46NV5@74030|Roseovarius	28211|Alphaproteobacteria	S	YcjX-like family, DUF463	MA20_04550	-	-	ko:K06918	-	-	-	-	ko00000	-	-	-	DUF463
CMS1_k127_5466108_3	1354722.JQLS01000008_gene1272	7.147e-106	347.0	COG0352@1|root,COG0352@2|Bacteria,1MV42@1224|Proteobacteria,2TSSA@28211|Alphaproteobacteria,46QD2@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0352 Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_5466108_2	1288298.rosmuc_01395	1.23e-118	387.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2TT8Q@28211|Alphaproteobacteria,46PVD@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_5466108_1	1354722.JQLS01000008_gene1270	1.519e-128	414.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2TUVA@28211|Alphaproteobacteria,46Q5Z@74030|Roseovarius	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
CMS1_k127_5466108_5	1354722.JQLS01000008_gene1269	2.173e-27	117.0	2E5JU@1|root,330B2@2|Bacteria,1N77B@1224|Proteobacteria,2UH27@28211|Alphaproteobacteria,46R9T@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3553)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3553
CMS1_k127_5466108_4	391613.RTM1035_09254	4.446e-46	173.0	COG5385@1|root,COG5385@2|Bacteria,1MVEY@1224|Proteobacteria,2TSE6@28211|Alphaproteobacteria,46QYG@74030|Roseovarius	28211|Alphaproteobacteria	S	Histidine phosphotransferase C-terminal domain	MA20_46320	-	-	ko:K13588	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001	-	-	-	HPTransfase
CMS1_k127_5481987_2	1288298.rosmuc_01333	5.191e-57	198.0	COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,2U5CQ@28211|Alphaproteobacteria,46QHJ@74030|Roseovarius	28211|Alphaproteobacteria	I	COG2030 Acyl dehydratase	phaJ	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
CMS1_k127_5481987_1	314264.ROS217_21212	2.463e-153	489.0	28IXU@1|root,2Z8VQ@2|Bacteria,1R3ZD@1224|Proteobacteria,2TTI3@28211|Alphaproteobacteria,46Q9M@74030|Roseovarius	28211|Alphaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
CMS1_k127_5481987_0	375451.RD1_3263	3.575e-216	675.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2P1HR@2433|Roseobacter	28211|Alphaproteobacteria	L	COG0513 Superfamily II DNA and RNA helicases	rhlE	-	3.6.4.13	ko:K03732,ko:K11927	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_5488343_11	391589.RGAI101_3808	1.163e-97	323.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2TU7G@28211|Alphaproteobacteria,2P4GM@2433|Roseobacter	28211|Alphaproteobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CMS1_k127_5488343_13	391589.RGAI101_3785	7.16e-55	203.0	2A9BJ@1|root,30YGJ@2|Bacteria,1Q5H0@1224|Proteobacteria,2VBUY@28211|Alphaproteobacteria,2P55Z@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5488343_1	391589.RGAI101_660	6.923e-256	791.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,2TRRQ@28211|Alphaproteobacteria,2P1IP@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1748 Saccharopine dehydrogenase and related proteins	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS1_k127_5488343_3	391589.RGAI101_3432	5.992e-214	668.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,2TVR1@28211|Alphaproteobacteria,2P37R@2433|Roseobacter	28211|Alphaproteobacteria	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
CMS1_k127_5488343_10	290400.Jann_3249	1.414e-102	341.0	COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2TRVK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5488343_6	1354722.JQLS01000008_gene2555	2.079e-165	526.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TRZE@28211|Alphaproteobacteria,46PXS@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_5488343_12	391613.RTM1035_02100	4.899e-79	266.0	COG3090@1|root,COG3090@2|Bacteria,1NCQX@1224|Proteobacteria,2VG03@28211|Alphaproteobacteria,46NVK@74030|Roseovarius	28211|Alphaproteobacteria	G	COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_5488343_2	1354722.JQLS01000008_gene2553	6.515e-241	750.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,46QMT@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	tauM	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_5488343_0	1354722.JQLS01000008_gene2552	7.055e-298	933.0	2DBDS@1|root,2Z8NX@2|Bacteria,1QWVI@1224|Proteobacteria,2TYEJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	3.5.1.56	ko:K03418	ko00630,map00630	-	R02509	RC00111,RC00731	ko00000,ko00001,ko01000	-	-	-	Laminin_G_3
CMS1_k127_5488343_4	1443111.JASG01000004_gene164	1.016e-181	575.0	COG3454@1|root,COG3454@2|Bacteria,1MV7H@1224|Proteobacteria,2TQMS@28211|Alphaproteobacteria,3ZVSU@60136|Sulfitobacter	28211|Alphaproteobacteria	P	Phosphonate metabolism	phnM	GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0044237,GO:0046434,GO:0071704,GO:1901575	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_5488343_14	1122614.JHZF01000011_gene2029	4.952e-51	189.0	COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,2UC24@28211|Alphaproteobacteria,2PEFK@252301|Oceanicola	28211|Alphaproteobacteria	P	Guanylate kinase homologues.	phnN	-	2.7.4.23	ko:K05774	ko00030,map00030	-	R06836	RC00002	ko00000,ko00001,ko01000	-	-	-	AAA_18,Guanylate_kin
CMS1_k127_5488343_9	391589.RGAI101_3304	2.045e-119	387.0	COG4778@1|root,COG4778@2|Bacteria,1MUPB@1224|Proteobacteria,2TR7T@28211|Alphaproteobacteria,2P19P@2433|Roseobacter	28211|Alphaproteobacteria	P	COG4778 ABC-type phosphonate transport system, ATPase component	phnL	GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1990234	2.7.8.37	ko:K05780	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	ABC_tran
CMS1_k127_5488343_7	1300350.DSW25_04555	5.962e-153	486.0	COG4107@1|root,COG4107@2|Bacteria,1MVRN@1224|Proteobacteria,2TQXF@28211|Alphaproteobacteria,3ZUYN@60136|Sulfitobacter	28211|Alphaproteobacteria	P	ABC transporter	phnK	-	-	ko:K05781	-	-	-	-	ko00000	-	-	-	ABC_tran,oligo_HPY
CMS1_k127_5488343_5	391589.RGAI101_3622	7.118e-176	553.0	COG3627@1|root,COG3627@2|Bacteria,1MV7T@1224|Proteobacteria,2TRKP@28211|Alphaproteobacteria,2P224@2433|Roseobacter	28211|Alphaproteobacteria	H	Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose	phnJ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016829,GO:0018835,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0098848,GO:1901575,GO:1902494,GO:1904176	4.7.1.1	ko:K06163	ko00440,map00440	-	R10204	RC03078,RC03079	ko00000,ko00001,ko01000	-	-	-	PhnJ
CMS1_k127_5488343_8	391626.OAN307_c26770	5.724e-151	479.0	COG3626@1|root,COG3626@2|Bacteria,1MUBA@1224|Proteobacteria,2TR4C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	enzyme of phosphonate metabolism	phnI	GO:0003674,GO:0003824,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061693,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1904176,GO:1990234	2.7.8.37	ko:K06164	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	PhnI
CMS1_k127_5491390_2	314264.ROS217_17892	9.4e-10	62.0	2DHTP@1|root,300X5@2|Bacteria,1RDAJ@1224|Proteobacteria,2U7CF@28211|Alphaproteobacteria,46QDF@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5491390_0	1354722.JQLS01000008_gene1053	0.0	1289.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,46Q0X@74030|Roseovarius	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_5491390_1	391613.RTM1035_10185	1.276e-65	231.0	COG1171@1|root,COG1171@2|Bacteria,1QVNS@1224|Proteobacteria,2TUHW@28211|Alphaproteobacteria,46PYM@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1171 Threonine dehydratase	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
CMS1_k127_5517860_7	1354722.JQLS01000008_gene3492	7.164e-66	227.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,46NVD@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS1_k127_5517860_8	391613.RTM1035_18455	7.218e-63	231.0	28WBE@1|root,2ZIBU@2|Bacteria,1N471@1224|Proteobacteria,2U5HT@28211|Alphaproteobacteria,46QDM@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517860_0	1288298.rosmuc_00170	3.092e-235	731.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TTE1@28211|Alphaproteobacteria,46Q2W@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS1_k127_5517860_10	314264.ROS217_09787	3.554e-39	149.0	COG2198@1|root,COG2198@2|Bacteria,1N86D@1224|Proteobacteria,2UFAP@28211|Alphaproteobacteria,46R5D@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2198 FOG HPt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
CMS1_k127_5517860_1	314264.ROS217_09792	6.813e-232	722.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,2TS77@28211|Alphaproteobacteria,46PB2@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0784 FOG CheY-like receiver	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,Response_reg,SpoIIE
CMS1_k127_5517860_9	644107.SL1157_1107	1.015e-59	213.0	COG0494@1|root,COG0494@2|Bacteria,1RI5B@1224|Proteobacteria,2U9IF@28211|Alphaproteobacteria,4NC0Y@97050|Ruegeria	28211|Alphaproteobacteria	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_5517860_3	391613.RTM1035_18430	1.83e-187	589.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,46Q5H@74030|Roseovarius	28211|Alphaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS1_k127_5517860_5	1354722.JQLS01000008_gene3485	8.81e-90	300.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,46NNB@74030|Roseovarius	28211|Alphaproteobacteria	L	Including oxidative damage repair enzymes	MA20_44635	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_5517860_4	391613.RTM1035_18420	2.217e-173	550.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,46NTA@74030|Roseovarius	28211|Alphaproteobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd
CMS1_k127_5517860_2	1354722.JQLS01000008_gene3483	2.223e-189	599.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2TR40@28211|Alphaproteobacteria,46NI2@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	tRNA_U5-meth_tr
CMS1_k127_5517860_6	1354722.JQLS01000008_gene3482	1.107e-77	262.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,46PGI@74030|Roseovarius	28211|Alphaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_5518348_5	1288298.rosmuc_01440	4.819e-157	497.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2TTFE@28211|Alphaproteobacteria,46NI8@74030|Roseovarius	28211|Alphaproteobacteria	S	ATPase (AAA superfamily)	MA20_41470	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
CMS1_k127_5518348_6	1354722.JQLS01000008_gene1222	8.929e-157	498.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,46Q26@74030|Roseovarius	28211|Alphaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS1_k127_5518348_12	1288298.rosmuc_01438	9.997e-54	194.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria,46QX7@74030|Roseovarius	28211|Alphaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0003674,GO:0005215	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_5518348_13	391613.RTM1035_09029	6.68e-30	121.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2VB7K@28211|Alphaproteobacteria,46R6D@74030|Roseovarius	28211|Alphaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_5518348_2	391613.RTM1035_09034	2.741e-219	683.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,46Q4M@74030|Roseovarius	28211|Alphaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_5518348_0	1354722.JQLS01000008_gene1218	0.0	1460.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,46PSD@74030|Roseovarius	28211|Alphaproteobacteria	M	COG5009 Membrane carboxypeptidase penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS1_k127_5518348_4	1354722.JQLS01000008_gene1217	8.292e-169	539.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,46PUZ@74030|Roseovarius	28211|Alphaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase, family 3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
CMS1_k127_5518348_1	314264.ROS217_22677	1.509e-244	760.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,46Q3Y@74030|Roseovarius	28211|Alphaproteobacteria	M	membrane-associated Zn-dependent proteases 1	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS1_k127_5518348_3	1288298.rosmuc_00993	2.824e-190	607.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,46QGV@74030|Roseovarius	28211|Alphaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS1_k127_5518348_9	391613.RTM1035_12483	1.484e-119	390.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,46PRW@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS1_k127_5518348_8	1354722.JQLS01000008_gene788	3.048e-141	450.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,46NEC@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_5518348_10	1288298.rosmuc_00990	5.824e-102	336.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,46QJ6@74030|Roseovarius	28211|Alphaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS1_k127_5518348_7	1354722.JQLS01000008_gene786	3.832e-149	473.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,46PC1@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_5518348_11	314271.RB2654_04174	1.124e-69	242.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_5526567_0	1354722.JQLS01000008_gene1494	0.0	1513.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,46NG7@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the GcvT family	dmgdh3	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS1_k127_5526567_1	351016.RAZWK3B_17638	0.0	1496.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2P1PQ@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0665 Glycine D-amino acid oxidases (deaminating)	dmgdh1	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS1_k127_5526567_3	314264.ROS217_20552	1.964e-29	118.0	2E3IX@1|root,32YHC@2|Bacteria,1NCPM@1224|Proteobacteria,2UHA3@28211|Alphaproteobacteria,46R75@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5526567_2	292414.TM1040_1239	1.21e-138	441.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria,4NB5H@97050|Ruegeria	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	QU41_16170	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
CMS1_k127_5587359_4	351016.RAZWK3B_10281	2.206e-21	93.0	COG3921@1|root,COG3921@2|Bacteria,1PZMM@1224|Proteobacteria,2TR6H@28211|Alphaproteobacteria,2P2B7@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
CMS1_k127_5587359_2	1354722.JQLS01000008_gene2507	4.729e-161	512.0	COG4093@1|root,COG4093@2|Bacteria,1R5ZP@1224|Proteobacteria,2U3GC@28211|Alphaproteobacteria,46Q82@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2125
CMS1_k127_5587359_3	1288298.rosmuc_01894	1.614e-92	312.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U7C6@28211|Alphaproteobacteria,46NY8@74030|Roseovarius	28211|Alphaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	chaC	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
CMS1_k127_5587359_1	1354722.JQLS01000008_gene2505	2.132e-208	653.0	COG1511@1|root,COG1511@2|Bacteria,1NYJB@1224|Proteobacteria,2TSX0@28211|Alphaproteobacteria,46Q0I@74030|Roseovarius	28211|Alphaproteobacteria	S	MotA TolQ ExbB proton channel family	MA20_18055	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
CMS1_k127_5587359_0	1354722.JQLS01000008_gene2504	3.792e-250	785.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2TQKZ@28211|Alphaproteobacteria,46NTF@74030|Roseovarius	28211|Alphaproteobacteria	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS1_k127_5589610_1	391619.PGA1_c01070	7.541e-87	287.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,34DZD@302485|Phaeobacter	28211|Alphaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS1_k127_5589610_3	1294273.roselon_01504	1.703e-56	199.0	COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UCBQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	GTP-binding protein Era	MA20_15690	-	-	-	-	-	-	-	-	-	-	-	DUF1491
CMS1_k127_5589610_0	391613.RTM1035_14292	6.033e-125	404.0	COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,46P5W@74030|Roseovarius	28211|Alphaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS1_k127_5589610_2	1354722.JQLS01000008_gene2331	4.314e-68	235.0	COG1309@1|root,COG1309@2|Bacteria,1R59A@1224|Proteobacteria,2U08S@28211|Alphaproteobacteria,46NRX@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_5589610_4	391613.RTM1035_14262	2.825e-54	194.0	COG3709@1|root,COG3709@2|Bacteria,1RK3Z@1224|Proteobacteria,2U616@28211|Alphaproteobacteria,46Q2C@74030|Roseovarius	28211|Alphaproteobacteria	P	Protein of unknown function (DUF1045)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1045
CMS1_k127_5595604_3	314264.ROS217_06324	8.807e-70	239.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,46NDZ@74030|Roseovarius	28211|Alphaproteobacteria	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_5595604_4	391626.OAN307_c29110	1.969e-42	156.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_5595604_0	1354722.JQLS01000008_gene2562	1.425e-149	480.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,2TVMQ@28211|Alphaproteobacteria,46PPY@74030|Roseovarius	28211|Alphaproteobacteria	S	Hydrolase, carbon-nitrogen family protein	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_5595604_2	999549.KI421513_gene770	4.331e-73	254.0	COG1802@1|root,COG1802@2|Bacteria,1RG3M@1224|Proteobacteria,2TV1M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG1802 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_5595604_1	388739.RSK20926_12204	9.928e-148	473.0	COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,2TUQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_5601462_1	351016.RAZWK3B_18433	2.151e-190	598.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,2P1V7@2433|Roseobacter	28211|Alphaproteobacteria	S	transport system, fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_5601462_0	1354722.JQLS01000008_gene3007	1.828e-273	843.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,46PUB@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_5611541_0	314264.ROS217_15111	1.242e-230	715.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,46PUE@74030|Roseovarius	28211|Alphaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_5611541_2	1288298.rosmuc_03108	1.322e-67	233.0	COG3474@1|root,COG3474@2|Bacteria,1N0S1@1224|Proteobacteria,2UC0E@28211|Alphaproteobacteria,46QUF@74030|Roseovarius	28211|Alphaproteobacteria	C	COG3474 Cytochrome c2	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_5611541_1	391613.RTM1035_05808	1.92e-75	254.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,46PMV@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_5625501_11	314264.ROS217_20507	6.864e-08	53.0	2BKYU@1|root,32FFG@2|Bacteria,1RHT5@1224|Proteobacteria,2UA28@28211|Alphaproteobacteria,46QPJ@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS1_k127_5625501_7	1354722.JQLS01000008_gene1482	3.215e-77	264.0	2C894@1|root,32RKM@2|Bacteria,1ND15@1224|Proteobacteria,2UBX2@28211|Alphaproteobacteria,46QMM@74030|Roseovarius	28211|Alphaproteobacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS1_k127_5625501_0	1288298.rosmuc_01560	5.337e-248	767.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TRNY@28211|Alphaproteobacteria,46NC4@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS1_k127_5625501_10	1123237.Salmuc_00714	1.145e-11	68.0	2EHX0@1|root,33BNM@2|Bacteria,1NGC2@1224|Proteobacteria,2UJHT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5625501_4	314264.ROS217_20492	2.207e-99	327.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2TTN7@28211|Alphaproteobacteria,46NNJ@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS1_k127_5625501_6	1288298.rosmuc_01563	1.505e-78	264.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria,46QNQ@74030|Roseovarius	28211|Alphaproteobacteria	I	COG2867 Oligoketide cyclase lipid transport protein	pasT	-	-	ko:K18588	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
CMS1_k127_5625501_1	314270.RB2083_4132	5.245e-220	685.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,3ZGC8@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_5625501_9	1188256.BASI01000003_gene2546	5.616e-59	209.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,3FD9A@34008|Rhodovulum	28211|Alphaproteobacteria	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
CMS1_k127_5625501_5	391613.RTM1035_08374	7.472e-79	268.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2UGK6@28211|Alphaproteobacteria,46QYP@74030|Roseovarius	28211|Alphaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CMS1_k127_5625501_2	1305735.JAFT01000005_gene3350	1.491e-154	497.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2PDMH@252301|Oceanicola	28211|Alphaproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
CMS1_k127_5625501_3	351016.RAZWK3B_15985	6.269e-153	490.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,2P1SA@2433|Roseobacter	28211|Alphaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_5625501_8	1288298.rosmuc_01568	3.333e-70	239.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,46NYD@74030|Roseovarius	28211|Alphaproteobacteria	T	COG3852 Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_5631749_4	351016.RAZWK3B_08786	6.936e-88	293.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2TS8M@28211|Alphaproteobacteria,2P10A@2433|Roseobacter	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_5631749_1	666509.RCA23_c22700	1.012e-175	552.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2TSNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1175 ABC-type sugar transport systems permease components	-	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_5631749_0	633131.TR2A62_3207	7.209e-234	727.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2TTMX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_8
CMS1_k127_5631749_2	391626.OAN307_c09160	1.423e-168	535.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.20	ko:K05816	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.3	-	-	ABC_tran,TOBE_2
CMS1_k127_5631749_3	1190606.AJYG01000192_gene2869	8.92e-97	325.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RPS0@1236|Gammaproteobacteria,1XZRJ@135623|Vibrionales	135623|Vibrionales	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
CMS1_k127_5631749_5	633131.TR2A62_1774	3.742e-42	158.0	COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TYM2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	sugar phosphatases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,Hydrolase_6,Hydrolase_like
CMS1_k127_5632504_2	314264.ROS217_18557	1.896e-11	66.0	2AJHH@1|root,31A42@2|Bacteria,1Q4W0@1224|Proteobacteria,2VBAN@28211|Alphaproteobacteria,46RC9@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5632504_0	1288298.rosmuc_03551	0.0	1224.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,46NBV@74030|Roseovarius	28211|Alphaproteobacteria	L	COG1200 RecG-like helicase	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS1_k127_5632504_1	1288298.rosmuc_03550	3e-323	994.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,46NJV@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
CMS1_k127_564072_6	1354722.JQLS01000008_gene1500	2.778e-57	201.0	2EC8K@1|root,33672@2|Bacteria,1NEDZ@1224|Proteobacteria,2UIFV@28211|Alphaproteobacteria,46QWH@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2059
CMS1_k127_564072_0	1354722.JQLS01000008_gene1501	1.589e-186	589.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2TSEA@28211|Alphaproteobacteria,46RQN@74030|Roseovarius	28211|Alphaproteobacteria	M	Lipid-A-disaccharide synthetase	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS1_k127_564072_3	1354722.JQLS01000008_gene1502	8.15e-123	398.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,2U4AB@28211|Alphaproteobacteria,46RGZ@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1009)	cdsA2	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
CMS1_k127_564072_2	351016.RAZWK3B_15343	1.685e-151	483.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,2P210@2433|Roseobacter	28211|Alphaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS1_k127_564072_4	314264.ROS217_20602	7.289e-89	298.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,46NUK@74030|Roseovarius	28211|Alphaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_564072_5	1354722.JQLS01000008_gene1505	1.455e-58	209.0	COG2825@1|root,COG2825@2|Bacteria,1MZ4B@1224|Proteobacteria,2UC2P@28211|Alphaproteobacteria,46QSJ@74030|Roseovarius	28211|Alphaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
CMS1_k127_564072_1	1354722.JQLS01000008_gene1506	4.812e-176	554.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,46P64@74030|Roseovarius	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS1_k127_5664503_2	1288298.rosmuc_00810	4.435e-244	755.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,46PUB@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_5664503_7	1288298.rosmuc_00811	3.554e-93	308.0	COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2U6K6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_5664503_1	314264.ROS217_11361	3.345e-247	765.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria,46PRN@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_5664503_6	314264.ROS217_11356	4.821e-122	394.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,46NFC@74030|Roseovarius	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	MA20_04615	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS1_k127_5664503_3	314264.ROS217_11351	1.186e-226	704.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,46PZD@74030|Roseovarius	28211|Alphaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	fadE	-	1.3.8.8	ko:K00255	ko00071,ko01100,ko01212,ko03320,map00071,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754	RC00052	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5664503_12	351016.RAZWK3B_07689	8.819e-35	133.0	2CD32@1|root,32RWY@2|Bacteria,1N00Z@1224|Proteobacteria,2UBQD@28211|Alphaproteobacteria,2P3UG@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5664503_0	391613.RTM1035_16902	0.0	1091.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,46QHC@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	MA20_19860	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS1_k127_5664503_10	1288298.rosmuc_00817	1.031e-61	216.0	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,2U98M@28211|Alphaproteobacteria,46QQW@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, merR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS1_k127_5664503_11	391613.RTM1035_16912	1.009e-56	209.0	COG0789@1|root,COG0789@2|Bacteria,1RH2P@1224|Proteobacteria,2U9RX@28211|Alphaproteobacteria,46QWM@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, merR family protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS1_k127_5664503_9	314264.ROS217_11326	5.477e-72	254.0	COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,2U72Z@28211|Alphaproteobacteria,46QS7@74030|Roseovarius	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	MA20_04725	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_5664503_8	1121271.AUCM01000012_gene2975	8.85e-85	284.0	COG2050@1|root,COG2050@2|Bacteria,1RITB@1224|Proteobacteria,2U58S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT,4HBT_3
CMS1_k127_5664503_4	1354722.JQLS01000008_gene2997	1.33e-225	705.0	COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,2TSKZ@28211|Alphaproteobacteria,46PP6@74030|Roseovarius	28211|Alphaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	dinF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS1_k127_5664503_5	391613.RTM1035_19856	2.178e-122	396.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2U0DN@28211|Alphaproteobacteria,46QAF@74030|Roseovarius	28211|Alphaproteobacteria	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
CMS1_k127_5671242_2	391613.RTM1035_13128	4.383e-92	304.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,46QEB@74030|Roseovarius	28211|Alphaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_5671242_0	391613.RTM1035_11745	0.0	1420.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,46NI4@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0210 Superfamily I DNA and RNA helicases	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_5671242_1	314264.ROS217_21922	1.751e-144	460.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,46P44@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	lldD2	-	1.1.2.3,1.1.99.31	ko:K00101,ko:K15054	ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120	-	R00196,R04160,R07664	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
CMS1_k127_5684633_7	314264.ROS217_13771	1.123e-99	328.0	COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,2TRJD@28211|Alphaproteobacteria,46NHW@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_5684633_6	351016.RAZWK3B_05657	8.804e-103	338.0	COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,2P32S@2433|Roseobacter	28211|Alphaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	-	-	-	-	-	-	-	-	-	LolA
CMS1_k127_5684633_5	398580.Dshi_3313	3.189e-112	367.0	COG0662@1|root,COG0662@2|Bacteria,1MX87@1224|Proteobacteria,2TRKJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dimethlysulfonioproprionate lyase	dddL	-	4.4.1.3	ko:K16953	ko00920,map00920	-	R02574	RC00747,RC00748	ko00000,ko00001,ko01000	-	-	-	DMSP_lyase
CMS1_k127_5684633_0	1530186.JQEY01000001_gene1039	0.0	1088.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_5684633_2	1354722.JQLS01000008_gene360	4.701e-228	709.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TQVM@28211|Alphaproteobacteria,46PWK@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	dapL	-	2.6.1.17	ko:K14261,ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5684633_1	1288298.rosmuc_02286	4.444e-229	715.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TSYS@28211|Alphaproteobacteria,46QE4@74030|Roseovarius	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_5684633_3	391613.RTM1035_02560	1.183e-219	695.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,46NSP@74030|Roseovarius	28211|Alphaproteobacteria	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family protein	ubiH	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS1_k127_5684633_8	1288298.rosmuc_02284	1.393e-93	309.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,46Q9T@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0742 N6-adenine-specific methylase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS1_k127_5684633_4	391613.RTM1035_02550	5.56e-201	629.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,46NN0@74030|Roseovarius	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase family protein	thcD	-	1.14.13.111,1.18.1.3	ko:K00529,ko:K16968	ko00071,ko00360,ko00920,ko01120,ko01220,map00071,map00360,map00920,map01120,map01220	M00545	R02000,R06782,R06783,R09513	RC00098,RC02556	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
CMS1_k127_5691138_9	1002340.AFCF01000052_gene1584	4.415e-31	122.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,34F5M@302485|Phaeobacter	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS1_k127_5691138_0	439496.RBY4I_4184	0.0	1180.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_5691138_2	351016.RAZWK3B_15008	1.404e-152	500.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,2P2DU@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_5691138_3	1354722.JQLS01000008_gene1948	2.204e-147	473.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2TV94@28211|Alphaproteobacteria,46QAD@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
CMS1_k127_5691138_8	1288298.rosmuc_01172	4.998e-86	289.0	COG1060@1|root,COG1060@2|Bacteria,1RCMC@1224|Proteobacteria,2U6RH@28211|Alphaproteobacteria,46P67@74030|Roseovarius	28211|Alphaproteobacteria	H	Haem-NO-binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
CMS1_k127_5691138_5	1354722.JQLS01000008_gene1950	4.611e-115	379.0	COG1116@1|root,COG1116@2|Bacteria,1RASI@1224|Proteobacteria,2U3AE@28211|Alphaproteobacteria,46NH7@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K15600	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	ABC_tran
CMS1_k127_5691138_6	1288298.rosmuc_01169	8.741e-102	336.0	COG0819@1|root,COG0819@2|Bacteria,1P18F@1224|Proteobacteria,2TWAS@28211|Alphaproteobacteria,46PND@74030|Roseovarius	28211|Alphaproteobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)	-	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
CMS1_k127_5691138_4	391613.RTM1035_06798	2.972e-134	430.0	COG0600@1|root,COG0600@2|Bacteria,1N0FV@1224|Proteobacteria,2U1I5@28211|Alphaproteobacteria,46P4T@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
CMS1_k127_5691138_7	1461693.ATO10_13844	5.598e-98	323.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,2TQWX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Co Zn Cd efflux system component	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
CMS1_k127_5691138_1	314264.ROS217_00100	1.957e-172	549.0	COG2771@1|root,COG2771@2|Bacteria	2|Bacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_5697124_1	314264.ROS217_17867	7.909e-177	556.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,46PF7@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	hipO1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_5697124_2	314264.ROS217_17862	4.607e-142	455.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,46PRU@74030|Roseovarius	28211|Alphaproteobacteria	S	Phosphoribosyl-ATP pyrophosphohydrolase	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
CMS1_k127_5697124_0	1354722.JQLS01000008_gene1119	0.0	1782.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,46NMK@74030|Roseovarius	28211|Alphaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS1_k127_5697124_3	314264.ROS217_18372	1.489e-59	208.0	COG2346@1|root,COG2346@2|Bacteria,1MZSM@1224|Proteobacteria,2UCHK@28211|Alphaproteobacteria,46QQT@74030|Roseovarius	28211|Alphaproteobacteria	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS1_k127_5700809_4	1415756.JQMY01000001_gene1949	2.66e-15	79.0	2C5G4@1|root,2Z7MU@2|Bacteria,1N9VI@1224|Proteobacteria,2TTAT@28211|Alphaproteobacteria,2PD52@252301|Oceanicola	28211|Alphaproteobacteria	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
CMS1_k127_5700809_2	1354722.JQLS01000008_gene2458	1.08e-113	368.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2TSWU@28211|Alphaproteobacteria,46NXB@74030|Roseovarius	28211|Alphaproteobacteria	L	COG1573 Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_5700809_3	1122614.JHZF01000013_gene3466	6.279e-103	337.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2TRMB@28211|Alphaproteobacteria,2PDNJ@252301|Oceanicola	28211|Alphaproteobacteria	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
CMS1_k127_5700809_1	1288298.rosmuc_03760	1.075e-182	576.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2TUB5@28211|Alphaproteobacteria,46QJA@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
CMS1_k127_5700809_0	1288298.rosmuc_03233	9.501e-214	670.0	COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2TWIP@28211|Alphaproteobacteria,46QDX@74030|Roseovarius	28211|Alphaproteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5705686_2	391613.RTM1035_07539	5.569e-77	260.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,46PXQ@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5705686_1	1288298.rosmuc_03652	1.001e-90	301.0	COG2080@1|root,COG2080@2|Bacteria,1RB3F@1224|Proteobacteria,2VF0C@28211|Alphaproteobacteria,46QDA@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_5705686_0	1354722.JQLS01000008_gene1671	3.968e-140	450.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria,46P3Y@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	xdhB	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_5706582_0	391595.RLO149_c015200	7.338e-226	707.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2V7R2@28211|Alphaproteobacteria,2P1Y3@2433|Roseobacter	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5706582_1	1354722.JQLS01000008_gene521	5.896e-110	359.0	COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,2TTAJ@28211|Alphaproteobacteria,46PG2@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3563 Capsule polysaccharide export protein	kpsC	-	-	ko:K07266	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS1_k127_5706582_2	1354722.JQLS01000008_gene521	1.03e-32	128.0	COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,2TTAJ@28211|Alphaproteobacteria,46PG2@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3563 Capsule polysaccharide export protein	kpsC	-	-	ko:K07266	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS1_k127_5707943_0	351016.RAZWK3B_18803	1.187e-236	734.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria,2P0YD@2433|Roseobacter	28211|Alphaproteobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS1_k127_5707943_5	1354722.JQLS01000008_gene2238	8.257e-73	248.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,46QAA@74030|Roseovarius	28211|Alphaproteobacteria	S	GatB YqeY domain protein	MA20_04985	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS1_k127_5707943_4	391613.RTM1035_04400	4.792e-84	280.0	COG5488@1|root,COG5488@2|Bacteria,1N4AH@1224|Proteobacteria,2VADQ@28211|Alphaproteobacteria,46NW9@74030|Roseovarius	28211|Alphaproteobacteria	S	COG5488 Integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2244
CMS1_k127_5707943_6	314264.ROS217_14991	2.831e-45	166.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5707943_3	391613.RTM1035_04395	4.165e-92	309.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria,46NGC@74030|Roseovarius	28211|Alphaproteobacteria	V	COG3023 Negative regulator of beta-lactamase expression	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	2.5.1.3,3.5.1.28	ko:K00788,ko:K01447,ko:K03806,ko:K11066	ko00730,ko01100,map00730,map01100	M00127	R03223,R04112,R10712	RC00064,RC00141,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1
CMS1_k127_5707943_2	314264.ROS217_14981	1.399e-92	309.0	2AYG7@1|root,31QJH@2|Bacteria,1RE73@1224|Proteobacteria,2U6WH@28211|Alphaproteobacteria,46NC5@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5707943_1	1354722.JQLS01000008_gene2242	1.169e-131	421.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,46PYX@74030|Roseovarius	28211|Alphaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_5708312_6	314271.RB2654_06314	1.929e-66	234.0	COG2271@1|root,COG2271@2|Bacteria,1QVY6@1224|Proteobacteria,2TWTV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5708312_5	1354722.JQLS01000008_gene1182	2.4e-129	416.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2TR57@28211|Alphaproteobacteria,46NGS@74030|Roseovarius	28211|Alphaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_5708312_0	314264.ROS217_21552	9.167e-293	902.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,46PAD@74030|Roseovarius	28211|Alphaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS1_k127_5708312_4	83219.PM02_01135	4.185e-133	426.0	COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2TTSB@28211|Alphaproteobacteria,3ZW7V@60136|Sulfitobacter	28211|Alphaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS1_k127_5708312_1	314264.ROS217_21542	1.698e-207	647.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2TT2U@28211|Alphaproteobacteria,46PN9@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_5708312_3	1354722.JQLS01000008_gene1186	6.488e-156	496.0	28IB8@1|root,2Z8DR@2|Bacteria,1N52H@1224|Proteobacteria,2TQYB@28211|Alphaproteobacteria,46PWD@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5708312_2	1288298.rosmuc_01265	7.808e-176	553.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria,46Q7P@74030|Roseovarius	28211|Alphaproteobacteria	S	AAA domain (dynein-related subfamily)	MA20_09400	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS1_k127_5709311_1	1443111.JASG01000004_gene1740	7.568e-174	551.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,3ZYSD@60136|Sulfitobacter	28211|Alphaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
CMS1_k127_5709311_3	1354722.JQLS01000008_gene2403	2.915e-33	132.0	COG2841@1|root,COG2841@2|Bacteria,1NNR7@1224|Proteobacteria,2UFB8@28211|Alphaproteobacteria,46R82@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
CMS1_k127_5709311_2	391613.RTM1035_04370	4.579e-93	310.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2UCUE@28211|Alphaproteobacteria,46NMM@74030|Roseovarius	28211|Alphaproteobacteria	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	-	-	-	-	-	-	-	-	-	-	-	-	SNase
CMS1_k127_5709311_0	1123247.AUIJ01000001_gene1651	7.585e-309	951.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_5715085_2	999549.KI421513_gene3583	9.535e-84	280.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,280EP@191028|Leisingera	28211|Alphaproteobacteria	T	Tetratricopeptide repeats	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	TPR_16,TPR_8,Trans_reg_C
CMS1_k127_5715085_1	1354722.JQLS01000008_gene3744	7.674e-109	361.0	2C5RM@1|root,319FB@2|Bacteria,1Q2JE@1224|Proteobacteria,2V9VS@28211|Alphaproteobacteria,46PGF@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5715085_0	314264.ROS217_08329	6.974e-172	549.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,46PGZ@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_5715085_3	1288298.rosmuc_00034	2.275e-42	156.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VG6E@28211|Alphaproteobacteria,46NU2@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, AsnC family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS1_k127_5723472_18	1123501.KB902315_gene3436	5.881e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_5723472_12	351016.RAZWK3B_07184	7.936e-59	204.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria,2P32B@2433|Roseobacter	28211|Alphaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS1_k127_5723472_2	375451.RD1_1399	1.025e-140	451.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria,2P11Q@2433|Roseobacter	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS1_k127_5723472_4	89187.ISM_01830	1.075e-117	380.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2TRUT@28211|Alphaproteobacteria,46QFH@74030|Roseovarius	28211|Alphaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS1_k127_5723472_15	1354722.JQLS01000008_gene306	2.925e-52	186.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2UBQ1@28211|Alphaproteobacteria,46R29@74030|Roseovarius	28211|Alphaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS1_k127_5723472_0	1354722.JQLS01000008_gene308	3.149e-176	554.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2TTKD@28211|Alphaproteobacteria,46NSZ@74030|Roseovarius	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS1_k127_5723472_14	391593.RCCS2_11297	3.394e-55	193.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2U95S@28211|Alphaproteobacteria,2P3E6@2433|Roseobacter	28211|Alphaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS1_k127_5723472_11	1354722.JQLS01000008_gene310	4.394e-71	241.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2U96X@28211|Alphaproteobacteria,46QSW@74030|Roseovarius	28211|Alphaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS1_k127_5723472_1	314264.ROS217_13391	7.911e-145	460.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,46PIX@74030|Roseovarius	28211|Alphaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS1_k127_5723472_9	314264.ROS217_13396	1.705e-79	265.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria,46QP4@74030|Roseovarius	28211|Alphaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS1_k127_5723472_5	1354722.JQLS01000008_gene313	9.193e-115	371.0	28H7B@1|root,2Z7JJ@2|Bacteria,1MX57@1224|Proteobacteria,2TQZS@28211|Alphaproteobacteria,46NIK@74030|Roseovarius	28211|Alphaproteobacteria	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
CMS1_k127_5723472_3	314264.ROS217_13416	6.522e-125	408.0	2E8VR@1|root,33360@2|Bacteria,1NA43@1224|Proteobacteria,2UACD@28211|Alphaproteobacteria,46QZ9@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5723472_6	391613.RTM1035_02880	1.879e-112	363.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2TQPF@28211|Alphaproteobacteria,46QN1@74030|Roseovarius	28211|Alphaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS1_k127_5723472_16	391613.RTM1035_02885	6.054e-52	185.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2UC01@28211|Alphaproteobacteria,46R2K@74030|Roseovarius	28211|Alphaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS1_k127_5723472_10	1354722.JQLS01000008_gene321	1.905e-72	245.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2U6ZH@28211|Alphaproteobacteria,46QRG@74030|Roseovarius	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS1_k127_5723472_8	1354722.JQLS01000008_gene322	5.781e-104	338.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria,46NYJ@74030|Roseovarius	28211|Alphaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS1_k127_5723472_13	391616.OA238_c36780	7.078e-58	205.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS1_k127_5723472_7	1354722.JQLS01000008_gene324	4.14e-105	342.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria,46NG9@74030|Roseovarius	28211|Alphaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS1_k127_5723472_17	83219.PM02_17985	1.181e-31	123.0	COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,3ZY46@60136|Sulfitobacter	28211|Alphaproteobacteria	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CMS1_k127_5738557_0	314264.ROS217_08054	0.0	1055.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQNH@28211|Alphaproteobacteria,46PTN@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_5738557_1	351016.RAZWK3B_07349	1.128e-33	129.0	COG1173@1|root,COG1173@2|Bacteria,1MU0P@1224|Proteobacteria,2TSX5@28211|Alphaproteobacteria,2P18M@2433|Roseobacter	28211|Alphaproteobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_5751469_3	375451.RD1_2400	3.48e-115	373.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,2TSYD@28211|Alphaproteobacteria,2P2I0@2433|Roseobacter	28211|Alphaproteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	2.3.1.28	ko:K00638	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Hexapep
CMS1_k127_5751469_0	1300350.DSW25_04515	3.904e-220	689.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2TTXJ@28211|Alphaproteobacteria,3ZWBC@60136|Sulfitobacter	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	phoT	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
CMS1_k127_5751469_2	1300350.DSW25_04510	1.193e-147	472.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2TUNJ@28211|Alphaproteobacteria,3ZV39@60136|Sulfitobacter	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	phoE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
CMS1_k127_5751469_1	52598.EE36_08848	2.965e-149	473.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,2TQMQ@28211|Alphaproteobacteria,3ZV0S@60136|Sulfitobacter	28211|Alphaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS1_k127_57743_7	1354722.JQLS01000008_gene1316	7.604e-55	192.0	COG5012@1|root,COG5012@2|Bacteria,1RDEU@1224|Proteobacteria,2TVXN@28211|Alphaproteobacteria,46Q5G@74030|Roseovarius	28211|Alphaproteobacteria	S	cobalamin binding protein	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
CMS1_k127_57743_2	89187.ISM_13445	2.284e-110	360.0	28I8Y@1|root,2Z8BR@2|Bacteria,1MXN1@1224|Proteobacteria,2TRAQ@28211|Alphaproteobacteria,46Q80@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
CMS1_k127_57743_5	314264.ROS217_19547	2.294e-68	235.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,46QRV@74030|Roseovarius	28211|Alphaproteobacteria	S	COG2166 SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
CMS1_k127_57743_6	1354722.JQLS01000008_gene1312	3.174e-61	215.0	2E41R@1|root,336C0@2|Bacteria,1NEN4@1224|Proteobacteria,2UGP6@28211|Alphaproteobacteria,46QQC@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_57743_0	1288298.rosmuc_03685	1.025e-197	628.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria,46NJ2@74030|Roseovarius	28211|Alphaproteobacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS1_k127_57743_3	1354722.JQLS01000008_gene1310	9.532e-107	355.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,46PMK@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
CMS1_k127_57743_1	391613.RTM1035_07684	6.751e-187	588.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,46NHA@74030|Roseovarius	28211|Alphaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_57743_4	644107.SL1157_0099	4.266e-84	288.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RBF3@1224|Proteobacteria,2VEYB@28211|Alphaproteobacteria,4NAPP@97050|Ruegeria	28211|Alphaproteobacteria	K	Transcriptional regulator, XRE family with cupin sensor	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS1_k127_5775111_1	1354722.JQLS01000008_gene732	1.975e-229	717.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,46PZE@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS1_k127_5775111_0	1354722.JQLS01000008_gene733	4.927e-252	787.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria,46QDH@74030|Roseovarius	28211|Alphaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS1_k127_5775111_3	1354722.JQLS01000008_gene743	1.688e-60	213.0	2AJ0U@1|root,319IW@2|Bacteria,1RGWP@1224|Proteobacteria,2U9I9@28211|Alphaproteobacteria,46QX4@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5775111_2	391613.RTM1035_05700	3.876e-61	213.0	COG3239@1|root,COG3239@2|Bacteria,1N42R@1224|Proteobacteria,2U06U@28211|Alphaproteobacteria,46NIS@74030|Roseovarius	28211|Alphaproteobacteria	C	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
CMS1_k127_57882_0	291985.CCSI01000004_gene806	1.224e-163	518.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TST2@28211|Alphaproteobacteria,2K189@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS1_k127_57882_1	161528.ED21_24576	3.548e-157	498.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,2K289@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
CMS1_k127_5806048_0	314264.ROS217_16605	2.681e-229	714.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,46NUF@74030|Roseovarius	28211|Alphaproteobacteria	C	COG2124 Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_5806048_1	1354722.JQLS01000008_gene674	7.753e-100	331.0	29QX6@1|root,30BXW@2|Bacteria,1RDIH@1224|Proteobacteria,2U79R@28211|Alphaproteobacteria,46NTX@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5806048_2	1266998.ATUJ01000006_gene49	4.392e-21	92.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,2PVIA@265|Paracoccus	28211|Alphaproteobacteria	J	GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_5815970_2	314264.ROS217_21262	1.254e-169	537.0	COG0168@1|root,COG0168@2|Bacteria,1MWV4@1224|Proteobacteria,2TQP5@28211|Alphaproteobacteria,46PMU@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0168 Trk-type K transport systems, membrane components	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_5815970_4	314264.ROS217_21257	4.674e-45	163.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,46R2F@74030|Roseovarius	28211|Alphaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
CMS1_k127_5815970_0	391613.RTM1035_09940	8.429e-231	719.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,46QC3@74030|Roseovarius	28211|Alphaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_5815970_1	246200.SPO1677	3.212e-227	706.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,4NBAS@97050|Ruegeria	28211|Alphaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS1_k127_5815970_5	314264.ROS217_18537	1.051e-38	147.0	2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,46R7D@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1153)	MA20_11245	-	-	-	-	-	-	-	-	-	-	-	DUF1153
CMS1_k127_5815970_3	314264.ROS217_18542	6.013e-142	452.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,46PUV@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02483,ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5821467_7	1354722.JQLS01000008_gene2508	3.724e-156	496.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,46PTG@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
CMS1_k127_5821467_11	1288298.rosmuc_01891	4.094e-94	315.0	COG0406@1|root,COG0406@2|Bacteria,1N41V@1224|Proteobacteria,2U09E@28211|Alphaproteobacteria,46QR3@74030|Roseovarius	28211|Alphaproteobacteria	G	Phosphoglycerate mutase family protein	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS1_k127_5821467_15	351016.RAZWK3B_05177	2.496e-76	259.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,2U98X@28211|Alphaproteobacteria,2P3C5@2433|Roseobacter	28211|Alphaproteobacteria	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobP	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
CMS1_k127_5821467_5	351016.RAZWK3B_05182	5.976e-165	521.0	COG0568@1|root,COG0568@2|Bacteria,1MUXA@1224|Proteobacteria,2TUED@28211|Alphaproteobacteria,2P2A5@2433|Roseobacter	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family	rpoH2	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
CMS1_k127_5821467_10	391613.RTM1035_13858	1.387e-104	345.0	COG3016@1|root,COG3016@2|Bacteria,1NXYQ@1224|Proteobacteria,2U0QY@28211|Alphaproteobacteria,46P8F@74030|Roseovarius	28211|Alphaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
CMS1_k127_5821467_3	1354722.JQLS01000008_gene2513	3.394e-210	658.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,46QKG@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038,ko:K21977	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_5821467_16	314264.ROS217_14211	5.943e-72	248.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,46QS2@74030|Roseovarius	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS1_k127_5821467_8	1123237.Salmuc_04112	2.493e-149	481.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_5821467_0	1354722.JQLS01000008_gene2516	0.0	1141.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria,46PBY@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0339 Zn-dependent oligopeptidases	dcp	GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS1_k127_5821467_1	1288298.rosmuc_01883	5.27e-317	972.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,46P5N@74030|Roseovarius	28211|Alphaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	algC	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_5821467_6	391613.RTM1035_13888	4.759e-161	509.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,46NMD@74030|Roseovarius	28211|Alphaproteobacteria	H	COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS1_k127_5821467_2	391613.RTM1035_13893	3.639e-247	774.0	COG3524@1|root,COG3524@2|Bacteria,1MUXV@1224|Proteobacteria,2TTK1@28211|Alphaproteobacteria,46NAZ@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3524 Capsule polysaccharide export protein	kpsE	-	-	ko:K01992,ko:K10107	ko02010,map02010	M00249,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.101	-	-	-
CMS1_k127_5821467_18	1185766.DL1_11590	3.149e-46	174.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2TU3M@28211|Alphaproteobacteria,2XMYN@285107|Thioclava	28211|Alphaproteobacteria	GM	ATPases associated with a variety of cellular activities	kpsT	-	3.6.3.38	ko:K09689	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101	-	-	ABC_tran
CMS1_k127_5821467_13	1288298.rosmuc_01878	3.264e-90	298.0	COG5328@1|root,COG5328@2|Bacteria,1RA93@1224|Proteobacteria,2U741@28211|Alphaproteobacteria,46QA3@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterised protein family (UPF0262)	MA20_21090	-	-	-	-	-	-	-	-	-	-	-	UPF0262
CMS1_k127_5821467_14	1288298.rosmuc_01877	1.772e-87	290.0	COG0394@1|root,COG0394@2|Bacteria,1RANV@1224|Proteobacteria,2U5EE@28211|Alphaproteobacteria,46PAM@74030|Roseovarius	28211|Alphaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	MA20_21085	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_5821467_17	1288298.rosmuc_01876	6.226e-70	241.0	COG3631@1|root,COG3631@2|Bacteria,1RH08@1224|Proteobacteria,2U96H@28211|Alphaproteobacteria,46QPI@74030|Roseovarius	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_5821467_12	501479.ACNW01000045_gene192	8.182e-93	310.0	COG0454@1|root,COG0454@2|Bacteria,1RDBA@1224|Proteobacteria,2TTF2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5821467_9	1354722.JQLS01000008_gene2525	3.141e-131	426.0	2C1HX@1|root,2Z7MF@2|Bacteria,1R7CM@1224|Proteobacteria,2TRAS@28211|Alphaproteobacteria,46P2S@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
CMS1_k127_5821467_4	1288298.rosmuc_01873	9.974e-200	627.0	COG2931@1|root,COG2931@2|Bacteria,1R4PX@1224|Proteobacteria,2TUD5@28211|Alphaproteobacteria,46NH8@74030|Roseovarius	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS1_k127_5821467_19	1305735.JAFT01000005_gene2025	2.562e-10	60.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,2PD00@252301|Oceanicola	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS1_k127_5839229_1	351016.RAZWK3B_06922	1.751e-30	122.0	COG0340@1|root,COG0340@2|Bacteria,1N1WU@1224|Proteobacteria,2TQK4@28211|Alphaproteobacteria,2P1PV@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0340 Biotin-(acetyl-CoA carboxylase) ligase	-	-	-	-	-	-	-	-	-	-	-	-	BPL_LplA_LipB_2,DUF4444
CMS1_k127_5839229_0	1288298.rosmuc_02445	5.699e-204	638.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,46PM1@74030|Roseovarius	28211|Alphaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS1_k127_5839229_2	391616.OA238_c08900	1.007e-26	110.0	2E7PS@1|root,3325B@2|Bacteria,1N7R7@1224|Proteobacteria,2UFCM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5845396_5	391613.RTM1035_02700	1.139e-52	189.0	2E3UV@1|root,32YS5@2|Bacteria,1N95I@1224|Proteobacteria,2UGVS@28211|Alphaproteobacteria,46QW1@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5845396_1	1288298.rosmuc_02319	2.742e-146	466.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,46QE8@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS1_k127_5845396_4	391613.RTM1035_02710	7.69e-70	237.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2UCJF@28211|Alphaproteobacteria,46QPN@74030|Roseovarius	28211|Alphaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS1_k127_5845396_2	1288298.rosmuc_02321	1.007e-110	364.0	COG3698@1|root,COG3698@2|Bacteria,1NH9S@1224|Proteobacteria,2TT5B@28211|Alphaproteobacteria,46PTT@74030|Roseovarius	28211|Alphaproteobacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
CMS1_k127_5845396_0	314264.ROS217_13266	9.113e-173	544.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,46PPD@74030|Roseovarius	28211|Alphaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
CMS1_k127_5845396_3	351016.RAZWK3B_02340	6.249e-97	319.0	COG4333@1|root,COG4333@2|Bacteria,1RGMJ@1224|Proteobacteria,2VGPN@28211|Alphaproteobacteria,2P5AD@2433|Roseobacter	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1643)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1643
CMS1_k127_5845396_6	1354722.JQLS01000008_gene231	1.056e-10	62.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,46NAP@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
CMS1_k127_585326_0	1288298.rosmuc_01005	6.026e-239	742.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,46NMN@74030|Roseovarius	28211|Alphaproteobacteria	E	Homoserine dehydrogenase	hom	GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS1_k127_585326_1	1288298.rosmuc_01004	8.592e-186	583.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,46P9A@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins	glpX	-	3.1.3.11,3.1.3.37	ko:K02446,ko:K11532	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
CMS1_k127_585326_2	314264.ROS217_17077	3.897e-66	229.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,46PBD@74030|Roseovarius	28211|Alphaproteobacteria	L	Exonuclease RecJ	recJ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_5909621_2	391626.OAN307_c04060	1.14e-08	63.0	COG2227@1|root,COG2227@2|Bacteria,1QYI9@1224|Proteobacteria,2TXSB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_5909621_1	644107.SL1157_0726	9.925e-108	358.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2TTFG@28211|Alphaproteobacteria,4NBID@97050|Ruegeria	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_5909621_0	1288298.rosmuc_02620	7.68e-181	570.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2TSZS@28211|Alphaproteobacteria,46P3H@74030|Roseovarius	28211|Alphaproteobacteria	LT	EXOIII	polC	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T,VRR_NUC
CMS1_k127_5914421_9	1417296.U879_10730	2.921e-35	138.0	COG0782@1|root,COG0782@2|Bacteria,1RHU5@1224|Proteobacteria,2U95I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
CMS1_k127_5914421_8	1288298.rosmuc_02144	1.78e-64	223.0	COG1051@1|root,COG1051@2|Bacteria,1RD52@1224|Proteobacteria,2U6ZA@28211|Alphaproteobacteria,46QPW@74030|Roseovarius	28211|Alphaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_5914421_5	1354722.JQLS01000008_gene2852	2.377e-121	394.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria,46NWR@74030|Roseovarius	28211|Alphaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS1_k127_5914421_2	314264.ROS217_12541	1.128e-178	566.0	COG3454@1|root,COG3454@2|Bacteria,1MXDS@1224|Proteobacteria,2TQU0@28211|Alphaproteobacteria,46P9T@74030|Roseovarius	28211|Alphaproteobacteria	P	COG3454 Metal-dependent hydrolase involved in phosphonate metabolism	-	-	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_5914421_1	1288298.rosmuc_00528	1.075e-187	592.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,46PRQ@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CMS1_k127_5914421_7	467661.RKLH11_986	1.218e-79	268.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,3ZH9M@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS1_k127_5914421_10	1354722.JQLS01000008_gene3032	9.087e-34	134.0	COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria,46R6M@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF465)	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
CMS1_k127_5914421_6	351016.RAZWK3B_10472	7.378e-82	274.0	COG0071@1|root,COG0071@2|Bacteria,1R9Y1@1224|Proteobacteria,2UA1J@28211|Alphaproteobacteria,2P31P@2433|Roseobacter	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspH	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
CMS1_k127_5914421_11	1354722.JQLS01000008_gene3030	2.382e-31	123.0	COG5568@1|root,COG5568@2|Bacteria,1N6UW@1224|Proteobacteria,2UF8P@28211|Alphaproteobacteria,46R4J@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1150)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1150
CMS1_k127_5914421_3	314264.ROS217_11486	1.954e-147	471.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2U3ND@28211|Alphaproteobacteria,46RGG@74030|Roseovarius	28211|Alphaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS1_k127_5914421_4	1354722.JQLS01000008_gene3028	8.928e-135	435.0	28H8X@1|root,2Z7KQ@2|Bacteria,1QVW0@1224|Proteobacteria,2U16Q@28211|Alphaproteobacteria,46RQY@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
CMS1_k127_5914421_0	89187.ISM_11065	0.0	1078.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VFZH@28211|Alphaproteobacteria,46PQ0@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,HTH_24,PUA_2
CMS1_k127_5915202_2	1423144.Gal_01205	2.658e-26	108.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,34FY2@302485|Phaeobacter	28211|Alphaproteobacteria	J	Ribosomal protein L33	rpmG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS1_k127_5915202_1	1288298.rosmuc_03005	2.789e-107	351.0	COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,46PGJ@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3773 Cell wall hydrolyses involved in spore germination	sleB	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
CMS1_k127_5915202_0	1354722.JQLS01000008_gene762	3.043e-159	503.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,46NY5@74030|Roseovarius	28211|Alphaproteobacteria	G	COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_5928242_0	1354722.JQLS01000008_gene3542	4.224e-245	760.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2TT55@28211|Alphaproteobacteria,46NRN@74030|Roseovarius	28211|Alphaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	soxF	-	1.8.2.3,1.8.5.4	ko:K17218,ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499,R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
CMS1_k127_5928242_4	391613.RTM1035_18765	3.021e-64	222.0	COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,2U95F@28211|Alphaproteobacteria,46QU4@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_5928242_1	391613.RTM1035_18770	1.568e-174	553.0	COG2391@1|root,COG2391@2|Bacteria,1MWWP@1224|Proteobacteria,2TQW4@28211|Alphaproteobacteria,46NRT@74030|Roseovarius	28211|Alphaproteobacteria	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
CMS1_k127_5928242_5	1123247.AUIJ01000004_gene1008	4.151e-64	228.0	COG0664@1|root,COG0664@2|Bacteria,1PIN3@1224|Proteobacteria,2TSA8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5928242_7	439496.RBY4I_94	1.102e-23	106.0	2C2VC@1|root,32WXZ@2|Bacteria,1P2P1@1224|Proteobacteria,2UEI8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
CMS1_k127_5928242_6	1123247.AUIJ01000004_gene1007	4.033e-24	103.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UKPX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_5928242_2	1288298.rosmuc_00059	1.365e-170	539.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TR8F@28211|Alphaproteobacteria,46NXA@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	soxH	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_5928242_3	1354722.JQLS01000008_gene3088	4.676e-155	493.0	COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TSXC@28211|Alphaproteobacteria,46NXK@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_5937215_3	1415756.JQMY01000001_gene3531	1.014e-120	388.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,2PD0P@252301|Oceanicola	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	1.14.13.24	ko:K22270	ko00362,ko01120,map00362,map01120	-	R02589	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
CMS1_k127_5937215_2	1208323.B30_19123	1.008e-132	424.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2TRTM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
CMS1_k127_5937215_4	391937.NA2_01475	3.071e-110	359.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,43IRM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	maleylacetoacetate isomerase	maiA	-	5.2.1.4	ko:K01801	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	GST_C_3,GST_N,GST_N_3
CMS1_k127_5937215_1	391937.NA2_01470	5.791e-224	696.0	COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2TUUS@28211|Alphaproteobacteria,43NHF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Cupin domain	-	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
CMS1_k127_5937215_5	471857.Svir_20680	6.211e-68	238.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria,4E4V6@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_C,MDMPI_N
CMS1_k127_5937215_0	391626.OAN307_c07010	0.0	1401.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TUTB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	dmgdh5	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS1_k127_5945751_0	1288298.rosmuc_01679	0.0	1916.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,46QM9@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_5945751_1	391613.RTM1035_14667	7.691e-76	259.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TUBY@28211|Alphaproteobacteria,46NH4@74030|Roseovarius	28211|Alphaproteobacteria	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
CMS1_k127_5947540_7	1288298.rosmuc_03650	9.622e-07	53.0	2B2CJ@1|root,31UWZ@2|Bacteria,1Q4W1@1224|Proteobacteria,2VBAP@28211|Alphaproteobacteria,46RCD@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5947540_2	1354722.JQLS01000008_gene1673	7.425e-146	466.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,46Q1J@74030|Roseovarius	28211|Alphaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS1_k127_5947540_1	1354722.JQLS01000008_gene1674	1.366e-211	660.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,46NXD@74030|Roseovarius	28211|Alphaproteobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS1_k127_5947540_5	1288298.rosmuc_03646	1.274e-50	181.0	2CDZD@1|root,32RYT@2|Bacteria,1N0AT@1224|Proteobacteria,2UBTM@28211|Alphaproteobacteria,46R27@74030|Roseovarius	28211|Alphaproteobacteria	S	Virulence factor	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
CMS1_k127_5947540_3	272942.RCAP_rcc01615	2.274e-129	420.0	COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria,1FAXP@1060|Rhodobacter	28211|Alphaproteobacteria	E	COG0685 5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_5947540_0	314264.ROS217_18832	1.773e-213	667.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TSBY@28211|Alphaproteobacteria,46Q1D@74030|Roseovarius	28211|Alphaproteobacteria	E	COG1410 Methionine synthase I, cobalamin-binding domain	acsE	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS1_k127_5947540_4	1288298.rosmuc_03642	2.805e-87	292.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,46PZ2@74030|Roseovarius	28211|Alphaproteobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_5947540_6	314262.MED193_22691	7.149e-39	151.0	COG3915@1|root,COG3915@2|Bacteria,1RHJS@1224|Proteobacteria,2U8BH@28211|Alphaproteobacteria,2P3C9@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS1_k127_5972118_0	1354722.JQLS01000008_gene86	0.0	1491.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,46P8J@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	dmgdh2	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS1_k127_5972118_8	999550.KI421507_gene567	9.159e-08	60.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2UDE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_5972118_6	1288298.rosmuc_00667	9.535e-93	314.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2TWNG@28211|Alphaproteobacteria,46P88@74030|Roseovarius	28211|Alphaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
CMS1_k127_5972118_3	351016.RAZWK3B_18613	1.145e-154	495.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2P21K@2433|Roseobacter	28211|Alphaproteobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5972118_5	1354722.JQLS01000008_gene81	1.728e-129	416.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,46NHH@74030|Roseovarius	28211|Alphaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS1_k127_5972118_4	1288298.rosmuc_00664	1.717e-137	441.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,46NN3@74030|Roseovarius	28211|Alphaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
CMS1_k127_5972118_1	391613.RTM1035_16147	8.78e-214	666.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,2TSZU@28211|Alphaproteobacteria,46Q2Z@74030|Roseovarius	28211|Alphaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	MA20_34830	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
CMS1_k127_5972118_2	1354722.JQLS01000008_gene77	1.374e-165	527.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSGJ@28211|Alphaproteobacteria,46PTA@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	MA20_34825	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS1_k127_5972118_7	1354722.JQLS01000008_gene76	4.809e-31	122.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TUGD@28211|Alphaproteobacteria,46PYJ@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS1_k127_5978726_3	1288298.rosmuc_02605	1.499e-72	245.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2TSA1@28211|Alphaproteobacteria,46QBP@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_5978726_0	1288298.rosmuc_02604	1.091e-275	854.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2TSPJ@28211|Alphaproteobacteria,46NBD@74030|Roseovarius	28211|Alphaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CMS1_k127_5978726_1	1288298.rosmuc_02603	4.128e-141	451.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TSC3@28211|Alphaproteobacteria,46P26@74030|Roseovarius	28211|Alphaproteobacteria	E	N-formylglutamate amidohydrolase	hutG	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
CMS1_k127_5978726_2	985054.JQEZ01000004_gene982	2.495e-126	411.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2TSJR@28211|Alphaproteobacteria,4NA67@97050|Ruegeria	28211|Alphaproteobacteria	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS1_k127_5983930_6	314264.ROS217_08474	8.308e-53	186.0	COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,2U851@28211|Alphaproteobacteria,46NUY@74030|Roseovarius	28211|Alphaproteobacteria	J	Including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS1_k127_5983930_1	351016.RAZWK3B_05447	3.406e-115	372.0	COG1670@1|root,COG1670@2|Bacteria,1PY0X@1224|Proteobacteria,2VEXD@28211|Alphaproteobacteria,2P1H6@2433|Roseobacter	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5983930_7	351016.RAZWK3B_05442	5.978e-51	182.0	COG1605@1|root,COG1605@2|Bacteria,1MZTQ@1224|Proteobacteria,2UCMC@28211|Alphaproteobacteria,2P38J@2433|Roseobacter	28211|Alphaproteobacteria	E	COG1605 Chorismate mutase	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
CMS1_k127_5983930_5	1354722.JQLS01000008_gene3773	8.398e-60	209.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,46QUQ@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS1_k127_5983930_2	1354722.JQLS01000008_gene3774	8.476e-104	342.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,2TTDR@28211|Alphaproteobacteria,46NAS@74030|Roseovarius	28211|Alphaproteobacteria	C	Cobalamin biosynthesis protein BluB	bluB	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CMS1_k127_5983930_3	1354722.JQLS01000008_gene3775	1.41e-86	289.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,46P51@74030|Roseovarius	28211|Alphaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS1_k127_5983930_8	1123237.Salmuc_05493	8.884e-44	171.0	2CJYU@1|root,32H5Z@2|Bacteria,1MYPI@1224|Proteobacteria,2U348@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5983930_0	314264.ROS217_08509	5.413e-145	464.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,46P96@74030|Roseovarius	28211|Alphaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS1_k127_5983930_4	1354722.JQLS01000008_gene3777	2.905e-68	233.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,46QQI@74030|Roseovarius	28211|Alphaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS1_k127_5983930_9	391613.RTM1035_17232	4.468e-40	152.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,46R6X@74030|Roseovarius	28211|Alphaproteobacteria	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS1_k127_598624_0	1354722.JQLS01000008_gene2533	2.67e-299	927.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,46NDB@74030|Roseovarius	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_598624_1	1354722.JQLS01000008_gene2532	7.528e-275	853.0	COG2303@1|root,COG2303@2|Bacteria,1MUK2@1224|Proteobacteria,2U08V@28211|Alphaproteobacteria,46NMY@74030|Roseovarius	28211|Alphaproteobacteria	E	And related flavoproteins	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_598624_3	314264.ROS217_14126	9.282e-117	381.0	COG1028@1|root,COG1028@2|Bacteria,1R814@1224|Proteobacteria,2TVA9@28211|Alphaproteobacteria,46QGS@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_598624_5	1288298.rosmuc_02650	1.08e-100	333.0	COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,2TSBS@28211|Alphaproteobacteria,46N9I@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase, WecB TagA CpsF family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
CMS1_k127_598624_2	1354722.JQLS01000008_gene204	5.176e-182	576.0	COG0673@1|root,COG0673@2|Bacteria,1MVT5@1224|Proteobacteria,2TV1T@28211|Alphaproteobacteria,46PAS@74030|Roseovarius	28211|Alphaproteobacteria	S	And related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_598624_4	1354722.JQLS01000008_gene205	8.816e-102	342.0	COG0451@1|root,COG0451@2|Bacteria,1RIHX@1224|Proteobacteria,2U9IA@28211|Alphaproteobacteria,46Q2U@74030|Roseovarius	28211|Alphaproteobacteria	GM	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GFO_IDH_MocA
CMS1_k127_598624_6	391613.RTM1035_15707	6.487e-84	280.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria,46PI1@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_5987397_1	351016.RAZWK3B_19391	4.748e-07	56.0	COG0699@1|root,COG0699@2|Bacteria,1R93D@1224|Proteobacteria,2U0MH@28211|Alphaproteobacteria,2P2XG@2433|Roseobacter	28211|Alphaproteobacteria	S	GTPases (dynamin-related)	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
CMS1_k127_5987397_0	351016.RAZWK3B_19386	6.786e-20	95.0	2DMH1@1|root,32RGM@2|Bacteria,1RJJQ@1224|Proteobacteria,2UAB5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5987397_2	999547.KI421501_gene4065	8.247e-07	60.0	2F3MX@1|root,33WF2@2|Bacteria,1NVRB@1224|Proteobacteria,2USCA@28211|Alphaproteobacteria,282DI@191028|Leisingera	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_59974_1	1354722.JQLS01000008_gene1499	3.924e-134	428.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,46QK9@74030|Roseovarius	28211|Alphaproteobacteria	P	COG3842 ABC-type spermidine putrescine transport systems, ATPase components	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS1_k127_59974_0	314264.ROS217_19467	6.093e-234	730.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria,46NY6@74030|Roseovarius	28211|Alphaproteobacteria	P	Mg2 and Co2 transporter CorB	corB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_59974_2	1354722.JQLS01000008_gene1287	1.986e-50	181.0	COG0639@1|root,COG0639@2|Bacteria,1PXN4@1224|Proteobacteria,2U09R@28211|Alphaproteobacteria,46PYC@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_6003922_2	1354722.JQLS01000008_gene671	2.336e-115	387.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TST2@28211|Alphaproteobacteria,46QIR@74030|Roseovarius	28211|Alphaproteobacteria	L	ATP-dependent RNA helicase, DEAD DEAH box family protein	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS1_k127_6003922_1	314264.ROS217_16600	1.876e-233	728.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,46PD1@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	MA20_09240	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_6003922_0	83219.PM02_16885	3.979e-260	808.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,3ZWVC@60136|Sulfitobacter	28211|Alphaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS1_k127_6003922_3	351016.RAZWK3B_17863	1.588e-109	359.0	2DB9X@1|root,2Z7ZS@2|Bacteria,1N6CK@1224|Proteobacteria,2U2ME@28211|Alphaproteobacteria,2P355@2433|Roseobacter	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3445)	-	-	1.14.13.238	ko:K22342	-	-	-	-	ko00000,ko01000	-	-	-	DUF3445
CMS1_k127_6007922_2	1288298.rosmuc_01671	7.593e-210	656.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,46P31@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_6007922_3	1288298.rosmuc_01672	4.725e-90	305.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,2TT1J@28211|Alphaproteobacteria,46NHF@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS1_k127_6007922_0	314264.ROS217_05179	0.0	1303.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,46NN4@74030|Roseovarius	28211|Alphaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
CMS1_k127_6007922_1	391613.RTM1035_15767	3.968e-217	680.0	COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria,46NHG@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2951 Membrane-bound lytic murein transglycosylase B	-	-	-	ko:K00786,ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	PG_binding_1,SLT_2
CMS1_k127_6007922_4	1354722.JQLS01000008_gene274	6.964e-82	279.0	COG3734@1|root,COG3734@2|Bacteria,1Q65M@1224|Proteobacteria,2VCDB@28211|Alphaproteobacteria,46PAH@74030|Roseovarius	28211|Alphaproteobacteria	G	2-keto-3-deoxy-galactonokinase	-	-	-	-	-	-	-	-	-	-	-	-	DGOK
CMS1_k127_6007922_5	1354722.JQLS01000008_gene273	2.184e-30	121.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UD2M@28211|Alphaproteobacteria,46QZJ@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442
CMS1_k127_6022331_3	1354722.JQLS01000008_gene1141	2.013e-115	374.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,46PNY@74030|Roseovarius	28211|Alphaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS1_k127_6022331_1	1288298.rosmuc_03142	4.889e-121	398.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,46NS3@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980,ko:K22073	-	-	-	-	ko00000,ko01000,ko03016,ko03029	-	-	-	GCV_T,GCV_T_C
CMS1_k127_6022331_4	1288298.rosmuc_03143	2.305e-98	325.0	COG0463@1|root,COG0463@2|Bacteria,1R4Y2@1224|Proteobacteria,2U6HZ@28211|Alphaproteobacteria,46PS5@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	MA20_42350	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_6022331_2	1354722.JQLS01000008_gene2023	6.839e-120	411.0	COG2365@1|root,COG2365@2|Bacteria,1REIM@1224|Proteobacteria,2U7HD@28211|Alphaproteobacteria,46RFZ@74030|Roseovarius	28211|Alphaproteobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF442,Y_phosphatase3
CMS1_k127_6022331_0	1354722.JQLS01000008_gene2022	8.441e-216	675.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,46PIH@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	MA20_39235	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_6027289_0	1288298.rosmuc_00915	4.483e-245	761.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,46P57@74030|Roseovarius	28211|Alphaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS1_k127_6027289_1	1288298.rosmuc_00125	1.159e-97	322.0	COG0477@1|root,COG2814@2|Bacteria,1QUD1@1224|Proteobacteria,2TWB1@28211|Alphaproteobacteria,46PX2@74030|Roseovarius	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_6038354_2	1288298.rosmuc_00954	3.002e-73	248.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2U7XQ@28211|Alphaproteobacteria,46QN0@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_6038354_1	351016.RAZWK3B_01645	5.332e-103	338.0	COG1280@1|root,COG1280@2|Bacteria,1RET0@1224|Proteobacteria,2TT5R@28211|Alphaproteobacteria,2P2ZD@2433|Roseobacter	28211|Alphaproteobacteria	P	threonine efflux protein	MA20_02350	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_6038354_3	1354722.JQLS01000008_gene2091	2.31e-63	224.0	COG4126@1|root,COG4126@2|Bacteria,1RIP0@1224|Proteobacteria,2U7HN@28211|Alphaproteobacteria,46R2Y@74030|Roseovarius	28211|Alphaproteobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6038354_0	1288298.rosmuc_00952	3.164e-147	467.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,46NH6@74030|Roseovarius	28211|Alphaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS1_k127_6039358_1	1342301.JASD01000008_gene2768	2.244e-17	85.0	28K40@1|root,2Z9T4@2|Bacteria,1R3V0@1224|Proteobacteria,2U1QP@28211|Alphaproteobacteria,3ZX19@60136|Sulfitobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6039358_0	1354722.JQLS01000008_gene804	0.0	1294.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,46Q0B@74030|Roseovarius	28211|Alphaproteobacteria	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS1_k127_6043834_2	1354722.JQLS01000008_gene734	3.508e-63	218.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2U79I@28211|Alphaproteobacteria,46QQK@74030|Roseovarius	28211|Alphaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS1_k127_6043834_0	391613.RTM1035_12268	5.053e-225	701.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,46QBF@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	argE_1	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_6043834_1	1354722.JQLS01000008_gene873	2.256e-120	388.0	KOG2391@1|root,3279X@2|Bacteria,1RHDJ@1224|Proteobacteria,2U9SJ@28211|Alphaproteobacteria,46RSK@74030|Roseovarius	28211|Alphaproteobacteria	O	protein transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6043834_3	1461694.ATO9_01900	5.175e-25	103.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,2PDCN@252301|Oceanicola	28211|Alphaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS1_k127_6051395_1	1288298.rosmuc_00655	2.471e-249	773.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,46NJY@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA polymerase III, alpha subunit	dnaE	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS1_k127_6051395_5	1288298.rosmuc_00654	1.926e-23	100.0	COG2900@1|root,COG2900@2|Bacteria,1N7YP@1224|Proteobacteria,2UFXX@28211|Alphaproteobacteria,46R9W@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
CMS1_k127_6051395_0	314264.ROS217_07110	3.113e-296	918.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,46P9N@74030|Roseovarius	28211|Alphaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_6051395_2	1288298.rosmuc_00652	2.466e-184	588.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2TTQ4@28211|Alphaproteobacteria,46ND9@74030|Roseovarius	28211|Alphaproteobacteria	E	COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CMS1_k127_6051395_3	391613.RTM1035_16087	1.699e-131	422.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2TT0H@28211|Alphaproteobacteria,46PZ0@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS1_k127_6051395_4	314264.ROS217_07125	1.161e-91	306.0	COG3637@1|root,COG3637@2|Bacteria,1R4WV@1224|Proteobacteria,2U0V2@28211|Alphaproteobacteria,46PKK@74030|Roseovarius	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	MA20_19585	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
CMS1_k127_6052822_8	314264.ROS217_12181	5.088e-45	168.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,46PGR@74030|Roseovarius	28211|Alphaproteobacteria	C	COG3474 Cytochrome c2	cycM	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_6052822_3	314264.ROS217_12176	7.675e-165	524.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria,46NPE@74030|Roseovarius	28211|Alphaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
CMS1_k127_6052822_4	570952.ATVH01000011_gene639	1.928e-156	499.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,2JSUU@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_6052822_7	314264.ROS217_12171	1.774e-62	218.0	COG3427@1|root,COG3427@2|Bacteria,1N15B@1224|Proteobacteria,2UBS8@28211|Alphaproteobacteria,46QNB@74030|Roseovarius	28211|Alphaproteobacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_6052822_2	314264.ROS217_12166	3.681e-181	570.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2TVMG@28211|Alphaproteobacteria,46NR6@74030|Roseovarius	28211|Alphaproteobacteria	L	containing a Zn-finger, probably nucleic-acid-binding	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
CMS1_k127_6052822_0	1354722.JQLS01000008_gene148	5.144e-262	823.0	COG0737@1|root,COG0737@2|Bacteria,1MU11@1224|Proteobacteria,2TT40@28211|Alphaproteobacteria,46NWU@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CMS1_k127_6052822_9	1337093.MBE-LCI_1946	4.777e-11	63.0	COG0637@1|root,COG0637@2|Bacteria,1NF90@1224|Proteobacteria,2U9G8@28211|Alphaproteobacteria,2P9GZ@245186|Loktanella	28211|Alphaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_6052822_6	351016.RAZWK3B_06002	1.667e-67	233.0	COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,2U8R6@28211|Alphaproteobacteria,2P39F@2433|Roseobacter	28211|Alphaproteobacteria	T	protein-tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
CMS1_k127_6052822_5	1461694.ATO9_02390	2.258e-129	430.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,2PD0B@252301|Oceanicola	28211|Alphaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
CMS1_k127_6052822_1	1354722.JQLS01000008_gene2838	3.518e-219	684.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,46NAN@74030|Roseovarius	28211|Alphaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
CMS1_k127_6053159_3	1248916.ANFY01000011_gene1208	1.968e-32	129.0	COG3631@1|root,COG3631@2|Bacteria,1RJ29@1224|Proteobacteria	1224|Proteobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_6053159_2	314264.ROS217_16785	2.833e-89	299.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,46P3M@74030|Roseovarius	28211|Alphaproteobacteria	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_6053159_0	1354722.JQLS01000008_gene705	0.0	1149.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria,46PJW@74030|Roseovarius	28211|Alphaproteobacteria	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	prpE	-	6.2.1.1,6.2.1.17	ko:K01895,ko:K01908	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_6053159_1	89187.ISM_09586	1.04e-130	419.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,46PPC@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0281 Malic enzyme	dme	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_6076688_1	391613.RTM1035_16617	1.235e-76	263.0	COG0510@1|root,COG0510@2|Bacteria,1REZ9@1224|Proteobacteria,2U7TR@28211|Alphaproteobacteria,46R4K@74030|Roseovarius	28211|Alphaproteobacteria	M	choline kinase involved in LPS biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_6076688_0	1354722.JQLS01000008_gene2942	5.785e-230	715.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria,46Q38@74030|Roseovarius	28211|Alphaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_6088773_2	83219.PM02_07380	1.798e-28	117.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,3ZWEU@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
CMS1_k127_6088773_1	1288298.rosmuc_00808	5.445e-54	192.0	2C1XR@1|root,32T89@2|Bacteria,1N1HY@1224|Proteobacteria,2UCII@28211|Alphaproteobacteria,46R01@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6088773_0	351016.RAZWK3B_04957	1.801e-120	391.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TRPD@28211|Alphaproteobacteria,2P168@2433|Roseobacter	28211|Alphaproteobacteria	H	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS1_k127_6089713_3	1123247.AUIJ01000010_gene165	6.721e-41	151.0	COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,2U5CQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	dehydratase	phaJ	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
CMS1_k127_6089713_1	391613.RTM1035_09533	7.967e-159	505.0	COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria,46PDV@74030|Roseovarius	28211|Alphaproteobacteria	G	sugar phosphatases of the HAD superfamily	MA20_05625	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_6089713_2	1354722.JQLS01000008_gene1620	4.249e-76	258.0	COG1853@1|root,COG1853@2|Bacteria,1NESS@1224|Proteobacteria,2U10U@28211|Alphaproteobacteria,46Q0G@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	MA20_04755	-	1.16.8.1,1.5.1.36	ko:K00484,ko:K09024,ko:K13786	ko00240,ko00350,ko00740,ko00860,ko01100,ko01120,ko01220,map00240,map00350,map00740,map00860,map01100,map01120,map01220	-	R02698,R03299,R05218,R05705,R09748,R09750,R09936	RC00046,RC00126,RC01010,RC02732	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
CMS1_k127_6089713_0	1046724.KB889953_gene2361	6.074e-206	644.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	dctM	GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
CMS1_k127_6094937_7	631454.N177_2540	1.934e-05	48.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria,1JP06@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	NUDIX domain	mutT	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Acetyltransf_3,NUDIX,NUDIX_4
CMS1_k127_6094937_2	314264.ROS217_10392	2.409e-217	679.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,46NTD@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS1_k127_6094937_5	1288298.rosmuc_00399	1.802e-111	366.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,46PHG@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0760 Parvulin-like peptidyl-prolyl isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
CMS1_k127_6094937_0	1354722.JQLS01000008_gene3245	0.0	1568.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,46PSX@74030|Roseovarius	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_6094937_3	1354722.JQLS01000008_gene3244	2.038e-131	427.0	28UX0@1|root,2ZH0U@2|Bacteria,1RAEJ@1224|Proteobacteria,2U3EF@28211|Alphaproteobacteria,46PPM@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6094937_1	1354722.JQLS01000008_gene3243	6.217e-269	835.0	COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,2TR8C@28211|Alphaproteobacteria,46NQ4@74030|Roseovarius	28211|Alphaproteobacteria	MP	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	OmpA,PBP_like_2
CMS1_k127_6094937_4	1354722.JQLS01000008_gene3242	5.275e-125	405.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,46NPV@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the UPF0758 family	radC	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_6094937_6	1123247.AUIJ01000011_gene581	3.461e-34	131.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_6102161_7	290400.Jann_0440	4.471e-07	51.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	thcD	-	1.14.13.111,1.18.1.3	ko:K00529,ko:K16968	ko00071,ko00360,ko00920,ko01120,ko01220,map00071,map00360,map00920,map01120,map01220	M00545	R02000,R06782,R06783,R09513	RC00098,RC02556	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
CMS1_k127_6102161_4	391613.RTM1035_02545	8.904e-85	286.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,46Q7X@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0678 Peroxiredoxin	pmpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
CMS1_k127_6102161_6	1354722.JQLS01000008_gene467	8.276e-46	167.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,46R03@74030|Roseovarius	28211|Alphaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS1_k127_6102161_0	1354722.JQLS01000008_gene468	3.222e-220	687.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,46PK1@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_36195	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CMS1_k127_6102161_2	1288298.rosmuc_02549	1.043e-119	389.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2TV1D@28211|Alphaproteobacteria,46PX1@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0584 Glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_6102161_5	1354722.JQLS01000008_gene470	1.491e-73	258.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,46NIM@74030|Roseovarius	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS1_k127_6102161_1	391613.RTM1035_14422	1.331e-199	632.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,46PUG@74030|Roseovarius	28211|Alphaproteobacteria	M	COG0845 Membrane-fusion protein	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
CMS1_k127_6102161_3	314264.ROS217_04140	1.2e-114	373.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,2TR17@28211|Alphaproteobacteria,46NNZ@74030|Roseovarius	28211|Alphaproteobacteria	V	COG4618 ABC-type protease lipase transport system, ATPase and permease components	prsD	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
CMS1_k127_6107163_0	391613.RTM1035_06668	0.0	1021.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,46Q15@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
CMS1_k127_6107163_8	391613.RTM1035_06663	9.619e-67	230.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,46QA5@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS1_k127_6107163_5	1288298.rosmuc_01140	2.598e-96	316.0	COG1278@1|root,COG1278@2|Bacteria,1RAUE@1224|Proteobacteria,2U0S7@28211|Alphaproteobacteria,46NI6@74030|Roseovarius	28211|Alphaproteobacteria	K	Cold shock protein domain	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_6107163_4	1288298.rosmuc_01139	5.767e-107	351.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,46PQ4@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CMS1_k127_6107163_3	1354722.JQLS01000008_gene1986	2.262e-158	501.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,46PR4@74030|Roseovarius	28211|Alphaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI2	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_6107163_7	1288298.rosmuc_01137	3.775e-84	283.0	COG1280@1|root,COG1280@2|Bacteria,1MX0K@1224|Proteobacteria,2U7BW@28211|Alphaproteobacteria,46PU5@74030|Roseovarius	28211|Alphaproteobacteria	E	threonine efflux protein	rhtC	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_6107163_6	1354722.JQLS01000008_gene1989	5.086e-94	315.0	COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,2TUXK@28211|Alphaproteobacteria,46Q1Y@74030|Roseovarius	28211|Alphaproteobacteria	F	Acts on guanine, xanthine and to a lesser extent hypoxanthine	gpt	-	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS1_k127_6107163_1	1288298.rosmuc_01135	1.235e-224	699.0	COG0436@1|root,COG0436@2|Bacteria,1MUHD@1224|Proteobacteria,2TRDR@28211|Alphaproteobacteria,46NR7@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	aspC4	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_6107163_2	1354722.JQLS01000008_gene1991	1.052e-217	684.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,46Q1Z@74030|Roseovarius	28211|Alphaproteobacteria	O	COG0760 Parvulin-like peptidyl-prolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
CMS1_k127_6108098_4	1354722.JQLS01000008_gene860	7.569e-66	225.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TQYV@28211|Alphaproteobacteria,46QID@74030|Roseovarius	28211|Alphaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_6108098_2	391613.RTM1035_12338	2.819e-145	463.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,46Q7S@74030|Roseovarius	28211|Alphaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_6108098_7	351016.RAZWK3B_19016	1.286e-07	56.0	291F0@1|root,2ZP1U@2|Bacteria,1P8Q4@1224|Proteobacteria,2UW49@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6108098_1	1288298.rosmuc_03162	1.169e-166	528.0	28I8A@1|root,2Z8B4@2|Bacteria,1MWJT@1224|Proteobacteria,2TUG9@28211|Alphaproteobacteria,46PC9@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6108098_0	1354722.JQLS01000008_gene864	4.658e-259	807.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,46P1V@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_6108098_3	314264.ROS217_17202	4.81e-96	317.0	COG2885@1|root,COG2885@2|Bacteria,1RAXN@1224|Proteobacteria,2U627@28211|Alphaproteobacteria,46P15@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS1_k127_6108098_5	1354722.JQLS01000008_gene866	3.914e-56	196.0	2CJPJ@1|root,32SAG@2|Bacteria,1N26R@1224|Proteobacteria,2UCCP@28211|Alphaproteobacteria,46R04@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6108098_6	1288298.rosmuc_03166	4.542e-43	159.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,46Q2Q@74030|Roseovarius	28211|Alphaproteobacteria	T	COG1702 Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS1_k127_6123632_1	1354722.JQLS01000008_gene236	1.914e-147	467.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2TU68@28211|Alphaproteobacteria,46NCB@74030|Roseovarius	28211|Alphaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS1_k127_6123632_0	391613.RTM1035_14097	7.652e-269	831.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,46P4Y@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	gor	GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_6123632_2	1288298.rosmuc_01839	1.946e-74	252.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,46PMN@74030|Roseovarius	28211|Alphaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS1_k127_6142920_1	1288298.rosmuc_01863	6.735e-38	143.0	COG3307@1|root,COG3307@2|Bacteria,1MV4S@1224|Proteobacteria,2TV8W@28211|Alphaproteobacteria,46NF0@74030|Roseovarius	28211|Alphaproteobacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6142920_0	391613.RTM1035_13973	1.115e-216	679.0	COG0438@1|root,COG0438@2|Bacteria,1P8MT@1224|Proteobacteria,2TRKC@28211|Alphaproteobacteria,46PBE@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_6142920_2	1354722.JQLS01000008_gene2533	4.329e-12	67.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,46NDB@74030|Roseovarius	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_6147608_2	1354722.JQLS01000008_gene567	2.34e-132	425.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,46NQ5@74030|Roseovarius	28211|Alphaproteobacteria	J	Pseudouridine synthase	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_6147608_13	375451.RD1_1812	1.05e-28	121.0	2E56U@1|root,32ZZI@2|Bacteria,1N750@1224|Proteobacteria,2UF4W@28211|Alphaproteobacteria,2P3P8@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6147608_14	391613.RTM1035_13473	2.017e-25	106.0	2E3H8@1|root,32YFX@2|Bacteria,1N7GV@1224|Proteobacteria,2UFBS@28211|Alphaproteobacteria,46R8I@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6147608_8	314264.ROS217_03665	1.967e-76	258.0	COG5321@1|root,COG5321@2|Bacteria,1RDXW@1224|Proteobacteria,2U73Y@28211|Alphaproteobacteria,46QQG@74030|Roseovarius	28211|Alphaproteobacteria	S	DNA repair protein MmcB-like	MA20_23405	-	-	-	-	-	-	-	-	-	-	-	MmcB-like
CMS1_k127_6147608_11	314264.ROS217_03670	8.766e-58	202.0	2E3EY@1|root,32YDV@2|Bacteria,1N8MQ@1224|Proteobacteria,2UG1Q@28211|Alphaproteobacteria,46R2C@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6147608_4	391613.RTM1035_15077	3.675e-104	340.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,46Q6H@74030|Roseovarius	28211|Alphaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_6147608_0	314264.ROS217_04969	2.132e-249	773.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria,46NZV@74030|Roseovarius	28211|Alphaproteobacteria	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_6147608_15	391613.RTM1035_15087	3.193e-07	53.0	2AD1V@1|root,312Q1@2|Bacteria,1PR1S@1224|Proteobacteria,2V3D3@28211|Alphaproteobacteria,46RBV@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6147608_9	351016.RAZWK3B_08946	6.158e-67	232.0	2A2U8@1|root,30R84@2|Bacteria,1REDA@1224|Proteobacteria,2U89J@28211|Alphaproteobacteria,2P3KZ@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6147608_12	1354722.JQLS01000008_gene2470	2.385e-56	203.0	28NAB@1|root,2ZBE5@2|Bacteria,1R6JX@1224|Proteobacteria,2U05Z@28211|Alphaproteobacteria,46QQH@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6147608_1	1354722.JQLS01000008_gene2471	7.086e-187	588.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2TRHP@28211|Alphaproteobacteria,46NF9@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_6147608_3	1354722.JQLS01000008_gene2472	1.133e-118	386.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,46P6Y@74030|Roseovarius	28211|Alphaproteobacteria	L	COG1573 Uracil-DNA glycosylase	udgA	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_6147608_7	246200.SPO0289	3.602e-91	303.0	COG2129@1|root,COG2129@2|Bacteria,1R3TH@1224|Proteobacteria,2U5Q8@28211|Alphaproteobacteria,4NA5C@97050|Ruegeria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_6147608_6	391613.RTM1035_15112	3.082e-94	320.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2TVFG@28211|Alphaproteobacteria,46QBV@74030|Roseovarius	28211|Alphaproteobacteria	E	Transmembrane amino acid efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_6147608_5	1354722.JQLS01000008_gene2474	1.469e-99	326.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2TTA8@28211|Alphaproteobacteria,46P35@74030|Roseovarius	28211|Alphaproteobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS1_k127_6147608_10	1288298.rosmuc_03771	5.995e-65	227.0	COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,2TQXT@28211|Alphaproteobacteria,46PAY@74030|Roseovarius	28211|Alphaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
CMS1_k127_6153230_2	351016.RAZWK3B_15613	1.272e-71	247.0	COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,2TUIH@28211|Alphaproteobacteria,2P1X8@2433|Roseobacter	28211|Alphaproteobacteria	K	Transcriptional regulator, TetR family	MA20_04045	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS1_k127_6153230_1	633131.TR2A62_0749	2.177e-81	278.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS1_k127_6153230_0	1288298.rosmuc_03560	2.09e-94	310.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,46PQG@74030|Roseovarius	28211|Alphaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS1_k127_6153230_3	314264.ROS217_18592	3.012e-61	212.0	COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,2U9BM@28211|Alphaproteobacteria,46QS0@74030|Roseovarius	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	MA20_36950	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_6155413_2	314264.ROS217_08840	5.516e-179	567.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2TV9J@28211|Alphaproteobacteria,46QBA@74030|Roseovarius	28211|Alphaproteobacteria	E	COG4448 L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
CMS1_k127_6155413_3	1288298.rosmuc_00514	3.736e-91	302.0	COG5342@1|root,COG5342@2|Bacteria,1R46Z@1224|Proteobacteria,2U5KW@28211|Alphaproteobacteria,46QKJ@74030|Roseovarius	28211|Alphaproteobacteria	S	invasion associated locus B	-	-	-	-	-	-	-	-	-	-	-	-	IalB
CMS1_k127_6155413_0	1354722.JQLS01000008_gene3104	1.116e-235	741.0	COG5316@1|root,COG5316@2|Bacteria,1N0IJ@1224|Proteobacteria,2TT1K@28211|Alphaproteobacteria,46QFT@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS1_k127_6155413_1	1288298.rosmuc_00332	6.624e-209	655.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,46PA8@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_6155413_4	1354722.JQLS01000008_gene3607	5.782e-39	147.0	COG2223@1|root,COG2223@2|Bacteria,1QU99@1224|Proteobacteria,2TW9H@28211|Alphaproteobacteria,46P4Z@74030|Roseovarius	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_6167380_3	1288298.rosmuc_03230	6.237e-72	244.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,46NTW@74030|Roseovarius	28211|Alphaproteobacteria	H	COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
CMS1_k127_6167380_1	391613.RTM1035_11988	1.238e-210	663.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,46PZ8@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0303 Molybdopterin biosynthesis enzyme	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_6167380_2	1354722.JQLS01000008_gene2596	4.1e-141	451.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,2TR8U@28211|Alphaproteobacteria,46NXW@74030|Roseovarius	28211|Alphaproteobacteria	K	DeoR C terminal sensor domain	glpR	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
CMS1_k127_6167380_0	1288298.rosmuc_03828	1.1e-290	898.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,46NSB@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS1_k127_6167380_4	314264.ROS217_06474	3.026e-07	51.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,46NKE@74030|Roseovarius	28211|Alphaproteobacteria	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS1_k127_6174847_1	571166.KI421509_gene876	2.149e-73	246.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
CMS1_k127_6174847_2	391613.RTM1035_13293	6.665e-58	203.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2UBS3@28211|Alphaproteobacteria,46QXD@74030|Roseovarius	28211|Alphaproteobacteria	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CMS1_k127_6174847_0	1354722.JQLS01000008_gene576	0.0	1491.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,46PAC@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0513 Superfamily II DNA and RNA helicases	mgpS	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
CMS1_k127_619960_2	1288298.rosmuc_01681	1.348e-104	341.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TUBY@28211|Alphaproteobacteria,46NH4@74030|Roseovarius	28211|Alphaproteobacteria	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
CMS1_k127_619960_0	1354722.JQLS01000008_gene2417	7.834e-218	680.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,46NWD@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_619960_1	1354722.JQLS01000008_gene2416	6.193e-167	526.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria,46NBK@74030|Roseovarius	28211|Alphaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_6206999_0	351016.RAZWK3B_02010	1.179e-215	670.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,2P1VC@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0665 Glycine D-amino acid oxidases (deaminating)	soxB2	-	1.5.3.1,1.5.99.5	ko:K00303,ko:K22084	ko00260,ko00680,ko01100,ko01120,map00260,map00680,map01100,map01120	-	R00609,R00610	RC00060,RC00190,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_6206999_2	375451.RD1_0011	1.118e-50	182.0	COG4311@1|root,COG4311@2|Bacteria,1N8ED@1224|Proteobacteria,2UFIN@28211|Alphaproteobacteria,2P3G9@2433|Roseobacter	28211|Alphaproteobacteria	C	COG4311 Sarcosine oxidase delta subunit	soxD	-	1.5.3.1,1.5.99.5	ko:K00304,ko:K22085	ko00260,ko00680,ko01100,ko01120,map00260,map00680,map01100,map01120	-	R00609,R00610	RC00060,RC00190,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
CMS1_k127_6206999_1	89187.ISM_09661	1.979e-152	484.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,46NVJ@74030|Roseovarius	28211|Alphaproteobacteria	C	Sarcosine oxidase, alpha subunit family protein	soxA2	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_6208452_1	1354722.JQLS01000008_gene3158	3.958e-45	165.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,46Q3Z@74030|Roseovarius	28211|Alphaproteobacteria	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_6208452_0	391613.RTM1035_17432	8.336e-253	785.0	COG0642@1|root,COG2205@2|Bacteria,1QV2U@1224|Proteobacteria,2TW9G@28211|Alphaproteobacteria,46PSI@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0642 Signal transduction histidine kinase	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS1_k127_6208452_2	314264.ROS217_10632	4.459e-35	143.0	COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria,46Q11@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2202 FOG PAS PAC domain	divL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,PAS_8
CMS1_k127_624739_2	351016.RAZWK3B_16535	1.555e-52	186.0	COG5467@1|root,COG5467@2|Bacteria,1MZRN@1224|Proteobacteria,2UC1G@28211|Alphaproteobacteria,2P3BI@2433|Roseobacter	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1476)	MA20_09035	-	-	-	-	-	-	-	-	-	-	-	DUF1476
CMS1_k127_624739_0	1354722.JQLS01000008_gene1319	8.712e-206	644.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2UJRS@28211|Alphaproteobacteria,46Q41@74030|Roseovarius	28211|Alphaproteobacteria	H	COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain	yitJ	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS1_k127_624739_1	1354722.JQLS01000008_gene1317	2.169e-138	444.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,46PQM@74030|Roseovarius	28211|Alphaproteobacteria	L	COG1533 DNA repair photolyase	MA20_42330	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_6252308_3	391624.OIHEL45_13255	5.04e-11	63.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0433 Predicted ATPase	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
CMS1_k127_6252308_0	1354722.JQLS01000008_gene1367	2.143e-126	417.0	COG2334@1|root,COG2334@2|Bacteria,1NJ9A@1224|Proteobacteria,2UK76@28211|Alphaproteobacteria,46P9X@74030|Roseovarius	28211|Alphaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_6252308_2	1354722.JQLS01000008_gene1368	2.646e-37	141.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,46R5F@74030|Roseovarius	28211|Alphaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS1_k127_6252308_1	1354722.JQLS01000008_gene1369	6.578e-100	330.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,46NCY@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_6262130_13	1354722.JQLS01000008_gene560	7.398e-27	109.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2U9IZ@28211|Alphaproteobacteria,46PB4@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS1_k127_6262130_3	391613.RTM1035_13498	1.04e-215	673.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria,46NFU@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS1_k127_6262130_6	1354722.JQLS01000008_gene558	6.248e-136	439.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2U3KZ@28211|Alphaproteobacteria,46PIY@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_6262130_2	1354722.JQLS01000008_gene557	1.145e-233	729.0	COG0112@1|root,COG0112@2|Bacteria,1MWDM@1224|Proteobacteria,2TS5T@28211|Alphaproteobacteria,46NS6@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0112 Glycine serine hydroxymethyltransferase	glyA_3	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS1_k127_6262130_11	985054.JQEZ01000004_gene966	1.109e-49	179.0	COG1917@1|root,COG1917@2|Bacteria,1MZD8@1224|Proteobacteria,2UBX5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_6262130_1	1354722.JQLS01000008_gene556	1.988e-241	749.0	COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,2TSQJ@28211|Alphaproteobacteria,46QG4@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3422
CMS1_k127_6262130_8	1288298.rosmuc_01952	2.847e-101	330.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,46P0X@74030|Roseovarius	28211|Alphaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_6262130_4	571166.KI421509_gene3847	1.203e-165	524.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_6262130_0	1288298.rosmuc_01951	8.637e-289	893.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,46NCK@74030|Roseovarius	28211|Alphaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
CMS1_k127_6262130_10	314264.ROS217_03720	3.745e-74	251.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria,46NTY@74030|Roseovarius	28211|Alphaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_6262130_7	1354722.JQLS01000008_gene551	7.686e-135	432.0	COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2TTYG@28211|Alphaproteobacteria,46Q9K@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	bdh	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_6262130_9	314256.OG2516_07268	4.829e-96	324.0	COG0745@1|root,COG0745@2|Bacteria,1R9AR@1224|Proteobacteria,2U2G3@28211|Alphaproteobacteria,2PETI@252301|Oceanicola	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_6262130_5	391613.RTM1035_13558	7.401e-153	485.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria,46N97@74030|Roseovarius	28211|Alphaproteobacteria	S	Peptidase C26	puuD	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS1_k127_6262130_12	1288298.rosmuc_01943	4.447e-28	114.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,46NJS@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0308 Aminopeptidase N	pepN	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
CMS1_k127_6268617_8	83219.PM02_19230	2.936e-30	121.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2TUCA@28211|Alphaproteobacteria,3ZZ64@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_6268617_3	67352.JODS01000031_gene832	8.288e-79	265.0	COG3558@1|root,COG3558@2|Bacteria,2IFFG@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
CMS1_k127_6268617_2	644107.SL1157_0422	4.186e-79	267.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2TUIS@28211|Alphaproteobacteria,4NB9G@97050|Ruegeria	28211|Alphaproteobacteria	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_6268617_4	314264.ROS217_19167	2.219e-51	191.0	2DQ0R@1|root,33492@2|Bacteria,1N2RB@1224|Proteobacteria,2UD8P@28211|Alphaproteobacteria,46PVE@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6268617_1	314264.ROS217_19162	7.456e-113	367.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,46PJT@74030|Roseovarius	28211|Alphaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS1_k127_6268617_6	314264.ROS217_19157	1.207e-34	137.0	2CGGD@1|root,32S3Y@2|Bacteria,1N74K@1224|Proteobacteria,2UFXV@28211|Alphaproteobacteria,46R45@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
CMS1_k127_6268617_0	1288298.rosmuc_01357	6.309e-128	411.0	COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria,46PXC@74030|Roseovarius	28211|Alphaproteobacteria	O	COG2214 DnaJ-class molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_6268617_7	1354722.JQLS01000008_gene1227	2.761e-31	123.0	2EGD6@1|root,33A4Z@2|Bacteria,1Q5FZ@1224|Proteobacteria,2VBU5@28211|Alphaproteobacteria,46R6G@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_6268617_5	1121479.AUBS01000004_gene2516	4.222e-35	138.0	2BY39@1|root,32YTT@2|Bacteria,1N9WR@1224|Proteobacteria,2UG9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6268617_9	314264.ROS217_19127	4.533e-28	113.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,46PH0@74030|Roseovarius	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_6275997_1	1121479.AUBS01000033_gene292	2.462e-85	284.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria	1224|Proteobacteria	P	Alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
CMS1_k127_6275997_2	1354722.JQLS01000008_gene711	5.256e-20	91.0	2EI1U@1|root,33BTA@2|Bacteria,1NGPK@1224|Proteobacteria,2UKG0@28211|Alphaproteobacteria,46R8D@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6275997_0	1354722.JQLS01000008_gene710	1.266e-133	429.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria,2TWBS@28211|Alphaproteobacteria,46PUX@74030|Roseovarius	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_6275997_4	1288298.rosmuc_01112	7.146e-06	49.0	2AJD4@1|root,319YK@2|Bacteria,1Q4G2@1224|Proteobacteria,2VAY0@28211|Alphaproteobacteria,46R1P@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6280207_4	391613.RTM1035_11615	3.799e-34	133.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,46PZ5@74030|Roseovarius	28211|Alphaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CMS1_k127_6280207_2	1354722.JQLS01000008_gene1803	1.443e-55	196.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2U95K@28211|Alphaproteobacteria,46R0M@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	MA20_41450	-	-	-	-	-	-	-	-	-	-	-	DUF498
CMS1_k127_6280207_1	999611.KI421504_gene3075	4.61e-73	255.0	COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,2U1B5@28211|Alphaproteobacteria,27ZE1@191028|Leisingera	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_6280207_0	1354722.JQLS01000008_gene1805	0.0	1477.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,46P1R@74030|Roseovarius	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_6280207_3	314264.ROS217_21817	7.585e-46	170.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,46R0P@74030|Roseovarius	28211|Alphaproteobacteria	U	translocase subunit yajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS1_k127_6281617_7	314264.ROS217_13781	2.776e-67	229.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,2U9MS@28211|Alphaproteobacteria,46QZI@74030|Roseovarius	28211|Alphaproteobacteria	S	Hemimethylated DNA-binding protein YccV like	hspQ	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
CMS1_k127_6281617_0	314264.ROS217_13786	8.76e-300	925.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,46Q3W@74030|Roseovarius	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_6281617_9	1354722.JQLS01000008_gene366	2.439e-43	163.0	COG2172@1|root,COG2172@2|Bacteria,1N7CT@1224|Proteobacteria,2UFUR@28211|Alphaproteobacteria,46R19@74030|Roseovarius	28211|Alphaproteobacteria	T	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS1_k127_6281617_8	314264.ROS217_13796	7.397e-48	174.0	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,2UBXI@28211|Alphaproteobacteria,46R36@74030|Roseovarius	28211|Alphaproteobacteria	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS1_k127_6281617_1	351016.RAZWK3B_05697	5.688e-212	664.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2P1G6@2433|Roseobacter	28211|Alphaproteobacteria	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_6281617_6	1354722.JQLS01000008_gene370	1.822e-75	257.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,46PQJ@74030|Roseovarius	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
CMS1_k127_6281617_4	314264.ROS217_13556	1.343e-124	400.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2TQYW@28211|Alphaproteobacteria,46QIE@74030|Roseovarius	28211|Alphaproteobacteria	J	RNA pseudouridylate synthase	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
CMS1_k127_6281617_2	1354722.JQLS01000008_gene190	1.981e-180	571.0	COG0515@1|root,COG0515@2|Bacteria,1QVSB@1224|Proteobacteria,2TWKG@28211|Alphaproteobacteria,46RD0@74030|Roseovarius	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6281617_3	89187.ISM_09170	1.31e-138	447.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1RD8N@1224|Proteobacteria,2U07K@28211|Alphaproteobacteria,46RMS@74030|Roseovarius	28211|Alphaproteobacteria	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
CMS1_k127_6281617_5	1354722.JQLS01000008_gene192	1.083e-86	290.0	COG3306@1|root,COG3306@2|Bacteria,1N6W4@1224|Proteobacteria,2UAWW@28211|Alphaproteobacteria,46PZB@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3306 Glycosyltransferase involved in LPS biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_25
CMS1_k127_6359_1	1288298.rosmuc_03774	1.797e-108	362.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,46P6G@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS1_k127_6359_0	1354722.JQLS01000008_gene2476	0.0	1682.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,46NEV@74030|Roseovarius	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_6359_2	1288298.rosmuc_03771	4.676e-104	344.0	COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,2TQXT@28211|Alphaproteobacteria,46PAY@74030|Roseovarius	28211|Alphaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
CMS1_k127_639724_1	998674.ATTE01000001_gene3389	4.179e-141	453.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctA	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
CMS1_k127_639724_2	998674.ATTE01000001_gene3388	2.327e-63	220.0	2CQ1K@1|root,32SKA@2|Bacteria,1N0TP@1224|Proteobacteria,1T00Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
CMS1_k127_639724_0	666509.RCA23_c26440	4.3e-166	526.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TTSX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
CMS1_k127_655775_0	314264.ROS217_04450	3.34e-258	799.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,46P30@74030|Roseovarius	28211|Alphaproteobacteria	L	Zn-dependent proteases and their inactivated homologs	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_655775_1	1288298.rosmuc_01744	5.401e-166	527.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,46NUT@74030|Roseovarius	28211|Alphaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CMS1_k127_655775_2	1288298.rosmuc_01745	1.701e-72	247.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,46PFP@74030|Roseovarius	28211|Alphaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS1_k127_66697_2	1354722.JQLS01000008_gene276	5.413e-161	512.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2TTZ4@28211|Alphaproteobacteria,46Q10@74030|Roseovarius	28211|Alphaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS1_k127_66697_1	1354722.JQLS01000008_gene275	9.397e-203	636.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria,46PH9@74030|Roseovarius	28211|Alphaproteobacteria	M	COG1519 3-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS1_k127_66697_3	351016.RAZWK3B_00735	2.349e-127	410.0	COG0518@1|root,COG0518@2|Bacteria,1PFE6@1224|Proteobacteria,2V9YD@28211|Alphaproteobacteria,2P53Z@2433|Roseobacter	2|Bacteria	F	COG0518 GMP synthase - Glutamine amidotransferase domain	guaA_2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS1_k127_66697_0	1288298.rosmuc_03288	7.832e-237	734.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,46Q8H@74030|Roseovarius	28211|Alphaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_668973_0	1354722.JQLS01000008_gene1685	5.87e-259	809.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,46NIG@74030|Roseovarius	28211|Alphaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS1_k127_668973_2	1208323.B30_09288	4.158e-48	175.0	2CF2J@1|root,32S52@2|Bacteria,1MZP1@1224|Proteobacteria,2UBUJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG3070 Regulator of competence-specific genes	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_C
CMS1_k127_668973_1	1288298.rosmuc_01420	7.032e-181	571.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,46Q1G@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_672973_4	351016.RAZWK3B_13594	7.303e-11	63.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2P2BA@2433|Roseobacter	28211|Alphaproteobacteria	L	COG0513 Superfamily II DNA and RNA helicases	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_672973_0	1354722.JQLS01000008_gene1033	1.084e-175	558.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,2TSPV@28211|Alphaproteobacteria,46Q35@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS1_k127_672973_1	351016.RAZWK3B_12247	8.868e-111	363.0	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,2U2SU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
CMS1_k127_672973_3	1461693.ATO10_11060	5.479e-63	221.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U5BD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS1_k127_672973_2	1288298.rosmuc_03401	1.024e-83	278.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria,46QF6@74030|Roseovarius	28211|Alphaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03768,ko:K09565	ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Pro_isomerase
CMS1_k127_686573_7	314264.ROS217_10477	1.793e-36	140.0	2CJVZ@1|root,2Z84M@2|Bacteria,1MVJ0@1224|Proteobacteria,2TTJI@28211|Alphaproteobacteria,46NAF@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_686573_6	314264.ROS217_10472	5.008e-89	294.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,46QHW@74030|Roseovarius	28211|Alphaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_686573_0	1288298.rosmuc_00413	0.0	1088.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,46P8A@74030|Roseovarius	28211|Alphaproteobacteria	C	Electrotransfer ubiquinone oxidoreductase family protein	etf	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
CMS1_k127_686573_1	1354722.JQLS01000008_gene3110	1.603e-287	891.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,46QJH@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	MA20_42300	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS1_k127_686573_5	314264.ROS217_10457	3.2e-108	356.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2TUFV@28211|Alphaproteobacteria,46NW7@74030|Roseovarius	28211|Alphaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_686573_2	1354722.JQLS01000008_gene3108	3.19e-184	580.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,46PIA@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_686573_8	1305735.JAFT01000005_gene716	8.355e-24	102.0	2E3KZ@1|root,32YJ8@2|Bacteria,1N7A7@1224|Proteobacteria,2UFMR@28211|Alphaproteobacteria,2PETS@252301|Oceanicola	28211|Alphaproteobacteria	S	Putative prokaryotic signal transducing protein	MA20_42240	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS1_k127_686573_4	1288298.rosmuc_00408	2.684e-119	387.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,2TUBR@28211|Alphaproteobacteria,46P16@74030|Roseovarius	28211|Alphaproteobacteria	S	Methyltransferase small domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
CMS1_k127_686573_9	1288298.rosmuc_00407	2.048e-18	86.0	COG5570@1|root,COG5570@2|Bacteria,1NGRE@1224|Proteobacteria,2UJAX@28211|Alphaproteobacteria,46R92@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
CMS1_k127_686573_3	314264.ROS217_11191	2.643e-140	447.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,46N9H@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	phbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS1_k127_707353_1	1123247.AUIJ01000004_gene1139	8.478e-135	432.0	COG4690@1|root,COG4690@2|Bacteria,1R4YQ@1224|Proteobacteria,2U2NP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
CMS1_k127_707353_0	1367847.JCM7686_2849	2.086e-185	588.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2PZ91@265|Paracoccus	28211|Alphaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
CMS1_k127_708209_0	1354722.JQLS01000008_gene2629	8.734e-185	584.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2TRVI@28211|Alphaproteobacteria,46P8I@74030|Roseovarius	28211|Alphaproteobacteria	S	Succinylglutamate desuccinylase aspartoacylase	doeB	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS1_k127_708209_2	1354722.JQLS01000008_gene2631	1.657e-90	306.0	COG2227@1|root,COG2227@2|Bacteria,1R6E0@1224|Proteobacteria,2U8FS@28211|Alphaproteobacteria,46P0M@74030|Roseovarius	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hen1_L,Methyltransf_23,Methyltransf_25
CMS1_k127_708209_1	391624.OIHEL45_07685	2.339e-122	394.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Peroxiredoxin	tsaA	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
CMS1_k127_708209_4	1288298.rosmuc_03865	6.864e-50	181.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46PJK@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	aldA	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_714207_2	314264.ROS217_15880	4.593e-36	141.0	2BMZ5@1|root,32GJ1@2|Bacteria,1MYYN@1224|Proteobacteria,2U99W@28211|Alphaproteobacteria,46QU8@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_714207_0	1288298.rosmuc_00961	3.637e-142	454.0	28INX@1|root,2Z8P0@2|Bacteria,1MWCP@1224|Proteobacteria,2U0Y7@28211|Alphaproteobacteria,46P5K@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_714207_1	1354722.JQLS01000008_gene2081	5.398e-57	200.0	2CJ7A@1|root,32S9D@2|Bacteria,1N1NT@1224|Proteobacteria,2UCA0@28211|Alphaproteobacteria,46QYT@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_714207_3	351016.RAZWK3B_05552	2.266e-30	120.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,2P10W@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS1_k127_717796_2	314264.ROS217_15455	1.603e-65	224.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,46PGH@74030|Roseovarius	28211|Alphaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS1_k127_717796_1	391613.RTM1035_04750	2.975e-166	526.0	COG0679@1|root,COG0679@2|Bacteria,1MY23@1224|Proteobacteria,2TR4M@28211|Alphaproteobacteria,46NVI@74030|Roseovarius	28211|Alphaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS1_k127_717796_0	1380367.JIBC01000003_gene4074	1.599e-244	757.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,3ZUSR@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	dgoD	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_720915_3	314264.ROS217_09420	2.182e-76	257.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TT3Y@28211|Alphaproteobacteria,46Q5I@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	ordL	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_720915_0	1288298.rosmuc_00244	1.155e-160	510.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,46QAZ@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_720915_1	1288298.rosmuc_00245	1.07e-102	334.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,46NN5@74030|Roseovarius	28211|Alphaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_720915_2	1402135.SUH3_09070	6.058e-86	286.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U5Q0@28211|Alphaproteobacteria,3ZX5J@60136|Sulfitobacter	28211|Alphaproteobacteria	O	This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS1_k127_720915_4	314264.ROS217_09400	7.605e-73	250.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2TU17@28211|Alphaproteobacteria,46Q6J@74030|Roseovarius	28211|Alphaproteobacteria	O	Glutathione peroxidase	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CMS1_k127_720915_5	391613.RTM1035_18050	3.935e-55	193.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,46NZ3@74030|Roseovarius	28211|Alphaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_722166_1	1288298.rosmuc_02083	1.881e-238	743.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,46PB3@74030|Roseovarius	28211|Alphaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_722166_0	1354722.JQLS01000008_gene814	8.41e-278	856.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,46PH2@74030|Roseovarius	28211|Alphaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_722166_3	314264.ROS217_23507	4.362e-121	395.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,46QE1@74030|Roseovarius	28211|Alphaproteobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS1_k127_722166_2	1288298.rosmuc_02080	4.244e-171	540.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,46PJ1@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	1.3.1.98,6.3.2.4	ko:K00075,ko:K01921	ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502	-	R01150,R03191,R03192	RC00064,RC00141,RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS1_k127_722166_4	351016.RAZWK3B_13099	2.845e-36	137.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,2P0XV@2433|Roseobacter	28211|Alphaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS1_k127_729228_1	314264.ROS217_19447	8.578e-79	268.0	COG3221@1|root,COG3221@2|Bacteria,1R6YE@1224|Proteobacteria,2U6QH@28211|Alphaproteobacteria,46NAU@74030|Roseovarius	28211|Alphaproteobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
CMS1_k127_729228_4	1288298.rosmuc_01407	1.918e-62	217.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2U93G@28211|Alphaproteobacteria,46QNJ@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS1_k127_729228_3	391613.RTM1035_09174	2.045e-69	237.0	COG4103@1|root,COG4103@2|Bacteria,1R941@1224|Proteobacteria,2U2UR@28211|Alphaproteobacteria,46QSZ@74030|Roseovarius	28211|Alphaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS1_k127_729228_2	314264.ROS217_19462	2.07e-74	254.0	2F5MI@1|root,33Y6N@2|Bacteria,1NWWQ@1224|Proteobacteria,2USFT@28211|Alphaproteobacteria,46QEI@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_729228_0	1288298.rosmuc_01541	4.689e-113	365.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,46P7V@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS1_k127_753066_4	1354722.JQLS01000008_gene627	8.265e-63	219.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2TS8V@28211|Alphaproteobacteria,46NE5@74030|Roseovarius	28211|Alphaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis	MA20_43810	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_753066_1	391613.RTM1035_05963	3.4e-115	376.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2TS0J@28211|Alphaproteobacteria,46PIV@74030|Roseovarius	28211|Alphaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_753066_3	1288298.rosmuc_03129	2.583e-96	320.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria,46PHV@74030|Roseovarius	28211|Alphaproteobacteria	E	COG2755 Lysophospholipase L1 and related esterases	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS1_k127_753066_5	314264.ROS217_23627	1.574e-53	190.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,46R4D@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_753066_2	1354722.JQLS01000008_gene2002	1.601e-104	343.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U60K@28211|Alphaproteobacteria,46QMG@74030|Roseovarius	28211|Alphaproteobacteria	S	ErfK YbiS YcfS YnhG family protein Tat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_753066_0	314264.ROS217_23617	1.717e-180	569.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRQD@28211|Alphaproteobacteria,46Q8D@74030|Roseovarius	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	MA20_01870	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1,Sugar_tr
CMS1_k127_753887_2	1354722.JQLS01000008_gene139	2.317e-129	418.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2TVI7@28211|Alphaproteobacteria,46Q44@74030|Roseovarius	28211|Alphaproteobacteria	M	protein involved in outer membrane biogenesis	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CMS1_k127_753887_0	1288298.rosmuc_00715	2.428e-272	858.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria,46P7T@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_753887_8	314264.ROS217_12086	1.332e-20	94.0	COG3011@1|root,COG3011@2|Bacteria,1N0S5@1224|Proteobacteria,2UDCQ@28211|Alphaproteobacteria,46QZE@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS1_k127_753887_4	391613.RTM1035_16352	1.454e-103	340.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2TSXY@28211|Alphaproteobacteria,46Q8R@74030|Roseovarius	28211|Alphaproteobacteria	S	Haemolysin-III related	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS1_k127_753887_7	1288298.rosmuc_00701	8.412e-33	132.0	2E9B0@1|root,333IV@2|Bacteria,1N7Y5@1224|Proteobacteria,2UFUP@28211|Alphaproteobacteria,46R4U@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_753887_5	1354722.JQLS01000008_gene116	9.689e-61	211.0	COG1739@1|root,COG1739@2|Bacteria,1RHG0@1224|Proteobacteria,2U9IC@28211|Alphaproteobacteria,46QW3@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterized protein family UPF0029	-	-	-	-	-	-	-	-	-	-	-	-	UPF0029
CMS1_k127_753887_3	1354722.JQLS01000008_gene115	6.876e-113	368.0	COG0501@1|root,COG0501@2|Bacteria,1R5XJ@1224|Proteobacteria,2V97Y@28211|Alphaproteobacteria,46NWK@74030|Roseovarius	28211|Alphaproteobacteria	O	Peptidase, M48 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_753887_6	391613.RTM1035_16332	1.141e-38	145.0	2CNWN@1|root,32SHY@2|Bacteria,1MZMG@1224|Proteobacteria,2UCKI@28211|Alphaproteobacteria,46R4R@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_753887_1	1288298.rosmuc_00697	6.62e-174	550.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,46P01@74030|Roseovarius	28211|Alphaproteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS1_k127_765575_6	314264.ROS217_22767	1.06e-188	597.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,46NGB@74030|Roseovarius	28211|Alphaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01928,ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_765575_3	314264.ROS217_22762	5.132e-216	677.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,46PQ2@74030|Roseovarius	28211|Alphaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS1_k127_765575_1	1354722.JQLS01000008_gene2014	1.04e-242	755.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,46NI5@74030|Roseovarius	28211|Alphaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_765575_4	1288298.rosmuc_02074	4.911e-201	632.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria,46P32@74030|Roseovarius	28211|Alphaproteobacteria	S	HI0933-like protein	yhiN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS1_k127_765575_2	1354722.JQLS01000008_gene806	4.698e-227	707.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria,46NUN@74030|Roseovarius	28211|Alphaproteobacteria	D	COG0772 Bacterial cell division membrane protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS1_k127_765575_5	1354722.JQLS01000008_gene807	6.187e-192	603.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,46P9W@74030|Roseovarius	28211|Alphaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS1_k127_765575_0	1461694.ATO9_13390	3.037e-272	841.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,2PCBU@252301|Oceanicola	28211|Alphaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_765575_7	314271.RB2654_00820	1.285e-140	457.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS1_k127_765575_9	1461694.ATO9_13385	7.645e-18	93.0	2EBV1@1|root,335UH@2|Bacteria,1NAEP@1224|Proteobacteria,2UFVT@28211|Alphaproteobacteria,2PEW3@252301|Oceanicola	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2484)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2484
CMS1_k127_765575_8	314264.ROS217_23522	4.021e-31	127.0	2E3A0@1|root,32Y9H@2|Bacteria,1N7SF@1224|Proteobacteria,2UFDS@28211|Alphaproteobacteria,46R4W@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2484)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2484
CMS1_k127_778337_0	351016.RAZWK3B_02000	0.0	1485.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,2P11E@2433|Roseobacter	28211|Alphaproteobacteria	C	Sarcosine oxidase, alpha subunit family	soxA2	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_778337_2	351016.RAZWK3B_01995	1.463e-71	247.0	COG4583@1|root,COG4583@2|Bacteria,1RC66@1224|Proteobacteria,2U5RU@28211|Alphaproteobacteria,2P396@2433|Roseobacter	28211|Alphaproteobacteria	E	COG4583 Sarcosine oxidase gamma subunit	soxGe	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
CMS1_k127_778337_1	351016.RAZWK3B_01990	8.894e-102	338.0	COG4977@1|root,COG4977@2|Bacteria,1R6CX@1224|Proteobacteria,2U44T@28211|Alphaproteobacteria,2P50Q@2433|Roseobacter	28211|Alphaproteobacteria	K	COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS1_k127_781501_1	1288298.rosmuc_00252	8.556e-56	197.0	COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,2TQM4@28211|Alphaproteobacteria,46PUD@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator, LacI family	-	-	-	ko:K06145	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CMS1_k127_781501_0	388739.RSK20926_11349	2.055e-116	381.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2TQUC@28211|Alphaproteobacteria,2P0ZC@2433|Roseobacter	28211|Alphaproteobacteria	S	proteins, homologs of lactam utilization protein B	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
CMS1_k127_781501_2	644107.SL1157_A0252	1.056e-13	72.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2TS7P@28211|Alphaproteobacteria,4NAMM@97050|Ruegeria	28211|Alphaproteobacteria	E	Allophanate hydrolase subunit 2	MA20_13140	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	CT_A_B
CMS1_k127_787352_3	644107.SL1157_A0247	1.394e-77	262.0	COG5631@1|root,COG5631@2|Bacteria,1RDM3@1224|Proteobacteria,2U72J@28211|Alphaproteobacteria,4NCB4@97050|Ruegeria	28211|Alphaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
CMS1_k127_787352_0	1530186.JQEY01000013_gene89	1.212e-215	675.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_787352_4	1185766.DL1_15545	3.134e-67	233.0	COG4665@1|root,COG4665@2|Bacteria,1QY3M@1224|Proteobacteria,2TXS4@28211|Alphaproteobacteria,2XNQ4@285107|Thioclava	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_787352_1	1353528.DT23_13700	5.07e-144	463.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,2TT88@28211|Alphaproteobacteria,2XMBW@285107|Thioclava	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_787352_2	1342299.Z947_4190	1.838e-81	278.0	COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,2U0AE@28211|Alphaproteobacteria,3ZV6H@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Allophanate hydrolase subunit 1	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	CT_C_D
CMS1_k127_787352_5	439496.RBY4I_74	8.817e-17	81.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2TS7P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	allophanate hydrolase subunit 2	MA20_13140	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	CT_A_B
CMS1_k127_807288_3	351016.RAZWK3B_04420	2.233e-120	389.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2P1WX@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.20,2.7.1.4	ko:K00847,ko:K00856	ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100	-	R00185,R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_807288_2	439496.RBY4I_657	1.33e-122	396.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2TRI2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS1_k127_807288_1	391613.RTM1035_20376	1.09e-147	472.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,46PTM@74030|Roseovarius	28211|Alphaproteobacteria	KL	COG2207 AraC-type DNA-binding domain-containing proteins	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18
CMS1_k127_807288_4	1354722.JQLS01000008_gene2949	1.865e-108	354.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,46PZA@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
CMS1_k127_807288_5	571166.KI421509_gene757	5.68e-40	150.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TTP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	bcpA	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
CMS1_k127_807288_0	1354722.JQLS01000008_gene3216	2.176e-258	802.0	COG3898@1|root,COG3898@2|Bacteria,1P5RR@1224|Proteobacteria,2TT5Q@28211|Alphaproteobacteria,46PYQ@74030|Roseovarius	28211|Alphaproteobacteria	S	enzyme of heme biosynthesis	lapB	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_19
CMS1_k127_807288_6	1354722.JQLS01000008_gene3217	3.35e-12	67.0	COG4223@1|root,COG4223@2|Bacteria,1RHEC@1224|Proteobacteria,2UAF8@28211|Alphaproteobacteria,46QEN@74030|Roseovarius	28211|Alphaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	Mitofilin
CMS1_k127_811485_2	1354722.JQLS01000008_gene1539	8.084e-27	111.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,46NNW@74030|Roseovarius	28211|Alphaproteobacteria	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	mccA	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_811485_0	351016.RAZWK3B_13294	1.44e-318	980.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,2P2E4@2433|Roseobacter	28211|Alphaproteobacteria	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	mccB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_811485_1	1353528.DT23_00570	9.845e-73	257.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,2XP3P@285107|Thioclava	28211|Alphaproteobacteria	M	OmpW family	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
CMS1_k127_821530_0	391589.RGAI101_3808	1.04e-248	780.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2TU7G@28211|Alphaproteobacteria,2P4GM@2433|Roseobacter	28211|Alphaproteobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CMS1_k127_821530_1	391589.RGAI101_4148	2.013e-16	85.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2U6QG@28211|Alphaproteobacteria,2P4YX@2433|Roseobacter	28211|Alphaproteobacteria	S	periplasmic or secreted lipoprotein	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
CMS1_k127_822789_0	1354722.JQLS01000008_gene3727	4.791e-258	799.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2TQKV@28211|Alphaproteobacteria,46QCB@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
CMS1_k127_822789_2	467661.RKLH11_3240	4.84e-116	381.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2TV0H@28211|Alphaproteobacteria,3ZGY0@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	nocR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_822789_1	314264.ROS217_08254	2.547e-175	559.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2TT7X@28211|Alphaproteobacteria,46PQ9@74030|Roseovarius	28211|Alphaproteobacteria	E	ornithine cyclodeaminase, mu-crystallin homolog	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS1_k127_822789_3	1530186.JQEY01000008_gene3028	4.517e-52	183.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid aldolase or racemase	dhaa	-	4.1.3.41	ko:K18425	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS1_k127_823029_2	314264.ROS217_08124	7.231e-97	323.0	COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,2U6P7@28211|Alphaproteobacteria,46P8C@74030|Roseovarius	28211|Alphaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS1_k127_823029_3	314264.ROS217_08114	3.81e-78	265.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2U79D@28211|Alphaproteobacteria,46QA1@74030|Roseovarius	28211|Alphaproteobacteria	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS1_k127_823029_0	1288298.rosmuc_00304	4.621e-263	814.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria,46NJ3@74030|Roseovarius	28211|Alphaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_823029_1	1354722.JQLS01000008_gene3345	2.379e-110	358.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,46Q27@74030|Roseovarius	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_835942_11	314264.ROS217_22102	1.636e-63	222.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,46QS9@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
CMS1_k127_835942_5	351016.RAZWK3B_09026	1.134e-110	366.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,2P164@2433|Roseobacter	28211|Alphaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_835942_10	246200.SPO0979	1.916e-69	238.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria,4NC9U@97050|Ruegeria	28211|Alphaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_835942_2	1288298.rosmuc_03721	9.715e-236	734.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TS04@28211|Alphaproteobacteria,46P4N@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD2	-	1.1.1.308	ko:K15509	-	-	-	-	ko00000,ko01000	-	-	-	Histidinol_dh
CMS1_k127_835942_6	314264.ROS217_19717	1.187e-106	350.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2U86Y@28211|Alphaproteobacteria,46NX2@74030|Roseovarius	28211|Alphaproteobacteria	M	Aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
CMS1_k127_835942_12	391613.RTM1035_11948	5.092e-57	201.0	2AI35@1|root,318GY@2|Bacteria,1RGYE@1224|Proteobacteria,2U9PN@28211|Alphaproteobacteria,46QXS@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_835942_0	1354722.JQLS01000008_gene1931	8.056e-315	974.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2TUGX@28211|Alphaproteobacteria,46NC1@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	BON,OmpA
CMS1_k127_835942_3	314264.ROS217_22117	1.279e-191	600.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,46Q6D@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179,ko:K06125	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117,M00128	R05000,R05615,R05616,R07273	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_835942_4	391613.RTM1035_11963	1.161e-128	419.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,46QDW@74030|Roseovarius	28211|Alphaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_835942_9	314264.ROS217_22127	1.544e-70	253.0	2CKED@1|root,32SC7@2|Bacteria,1MZAN@1224|Proteobacteria,2UCI6@28211|Alphaproteobacteria,46Q66@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_835942_1	314264.ROS217_22132	1.586e-287	884.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,46Q1X@74030|Roseovarius	28211|Alphaproteobacteria	H	COG3572 Gamma-glutamylcysteine synthetase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
CMS1_k127_835942_8	1288298.rosmuc_01958	1.958e-80	271.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria,46PDU@74030|Roseovarius	28211|Alphaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS1_k127_835942_7	351016.RAZWK3B_08159	2.181e-96	317.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2U9IZ@28211|Alphaproteobacteria,2P1SW@2433|Roseobacter	28211|Alphaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS1_k127_841648_2	1288298.rosmuc_02845	3.967e-81	280.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TT9M@28211|Alphaproteobacteria,46PJV@74030|Roseovarius	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS1_k127_841648_4	314264.ROS217_15026	1.038e-16	81.0	2C2JV@1|root,33CNW@2|Bacteria,1NKMC@1224|Proteobacteria,2UMN3@28211|Alphaproteobacteria,46R8P@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_841648_1	391613.RTM1035_04565	2.586e-114	373.0	COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,2TUDN@28211|Alphaproteobacteria,46PA5@74030|Roseovarius	28211|Alphaproteobacteria	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_841648_3	1446473.JHWH01000020_gene3859	1.769e-34	140.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2TUKM@28211|Alphaproteobacteria,2PU8R@265|Paracoccus	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_841648_0	314264.ROS217_15011	5.188e-311	962.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,2TR9F@28211|Alphaproteobacteria,46NAD@74030|Roseovarius	28211|Alphaproteobacteria	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,T2SSE_N
CMS1_k127_845043_5	314264.ROS217_18262	6.971e-56	196.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,46QGG@74030|Roseovarius	28211|Alphaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS1_k127_845043_2	314264.ROS217_07160	1.29e-172	546.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2TU43@28211|Alphaproteobacteria,46NJ6@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF808)	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
CMS1_k127_845043_6	1402135.SUH3_13920	8.414e-21	95.0	2BY39@1|root,32YTT@2|Bacteria,1N9WR@1224|Proteobacteria,2UG9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_845043_1	351016.RAZWK3B_09616	5.679e-182	574.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2TS3Z@28211|Alphaproteobacteria,2P28E@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_845043_3	351016.RAZWK3B_07599	6.023e-73	248.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2UC0B@28211|Alphaproteobacteria,2P3MZ@2433|Roseobacter	28211|Alphaproteobacteria	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
CMS1_k127_845043_4	1402135.SUH3_05365	2.874e-61	218.0	COG1802@1|root,COG1802@2|Bacteria,1RAW8@1224|Proteobacteria,2U5UI@28211|Alphaproteobacteria,3ZYRX@60136|Sulfitobacter	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_845043_0	999611.KI421504_gene3495	5.345e-215	673.0	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,2TRTH@28211|Alphaproteobacteria,281X2@191028|Leisingera	28211|Alphaproteobacteria	FH	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
CMS1_k127_853674_3	1354722.JQLS01000008_gene3172	2.113e-153	487.0	COG0477@1|root,COG2814@2|Bacteria,1QUD1@1224|Proteobacteria,2TWB1@28211|Alphaproteobacteria,46PX2@74030|Roseovarius	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_853674_11	1415756.JQMY01000001_gene491	5.978e-55	201.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2UCM1@28211|Alphaproteobacteria,2PE64@252301|Oceanicola	28211|Alphaproteobacteria	S	Smr domain	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS1_k127_853674_1	1288298.rosmuc_00137	1.823e-191	602.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,46P02@74030|Roseovarius	28211|Alphaproteobacteria	M	COG2821 Membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
CMS1_k127_853674_5	1288298.rosmuc_00138	9.758e-118	382.0	COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria,46Q8G@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_24770	-	-	-	-	-	-	-	-	-	-	-	Tim44
CMS1_k127_853674_10	351016.RAZWK3B_02795	4.715e-66	231.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,2UF72@28211|Alphaproteobacteria,2P3AV@2433|Roseobacter	28211|Alphaproteobacteria	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	fxsA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
CMS1_k127_853674_7	314264.ROS217_09667	5.115e-84	281.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,46NZZ@74030|Roseovarius	28211|Alphaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
CMS1_k127_853674_4	1288298.rosmuc_00192	3.014e-123	398.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,46NEG@74030|Roseovarius	28211|Alphaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS1_k127_853674_9	1122614.JHZF01000013_gene3295	1.592e-69	241.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,2PD5I@252301|Oceanicola	28211|Alphaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS1_k127_853674_2	1354722.JQLS01000008_gene3510	8.219e-156	494.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,46P93@74030|Roseovarius	28211|Alphaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS1_k127_853674_6	314264.ROS217_09687	8.128e-92	305.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2U9H5@28211|Alphaproteobacteria,46P1T@74030|Roseovarius	28211|Alphaproteobacteria	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_853674_8	314264.ROS217_09692	1.199e-73	251.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,46QU1@74030|Roseovarius	28211|Alphaproteobacteria	S	Uncharacterised protein family (UPF0093)	MA20_24805	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS1_k127_853674_0	1354722.JQLS01000008_gene3507	4.272e-223	694.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,46ND3@74030|Roseovarius	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_857009_3	1121479.AUBS01000014_gene1157	5.997e-136	436.0	COG0683@1|root,COG0683@2|Bacteria,1MUNS@1224|Proteobacteria,2TTNM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_857009_0	351016.RAZWK3B_03800	5.639e-204	643.0	arCOG02771@1|root,2Z93M@2|Bacteria,1QTY6@1224|Proteobacteria,2TWJ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_857009_2	1288298.rosmuc_00473	3.92e-181	590.0	28IN1@1|root,2Z8NH@2|Bacteria,1MWM2@1224|Proteobacteria,2TUUR@28211|Alphaproteobacteria,46NN7@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_857009_4	351016.RAZWK3B_02290	4.168e-93	310.0	COG1564@1|root,COG1564@2|Bacteria,1RE29@1224|Proteobacteria,2U7FB@28211|Alphaproteobacteria,2P365@2433|Roseobacter	28211|Alphaproteobacteria	H	COG1564 Thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
CMS1_k127_857009_1	314264.ROS217_09045	2.437e-193	608.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2U0DN@28211|Alphaproteobacteria,46QAF@74030|Roseovarius	28211|Alphaproteobacteria	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
CMS1_k127_866851_3	391613.RTM1035_17467	5.391e-111	366.0	COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,2TQU8@28211|Alphaproteobacteria,46NJR@74030|Roseovarius	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	opgH	GO:0005575,GO:0016020	-	ko:K03669	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.3.1.1	GT2	-	Glyco_trans_2_3
CMS1_k127_866851_0	1288298.rosmuc_00934	6.047e-245	766.0	COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,2TRU1@28211|Alphaproteobacteria,46Q9U@74030|Roseovarius	28211|Alphaproteobacteria	P	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)	mdoG	GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576	-	ko:K03670	-	-	-	-	ko00000	-	-	-	MdoG
CMS1_k127_866851_1	1288298.rosmuc_00935	2.246e-224	700.0	COG4645@1|root,COG4645@2|Bacteria,1PI9Q@1224|Proteobacteria,2U1C7@28211|Alphaproteobacteria,46NMJ@74030|Roseovarius	28211|Alphaproteobacteria	S	OpgC protein	opgC	-	-	-	-	-	-	-	-	-	-	-	OpgC_C
CMS1_k127_866851_2	1354722.JQLS01000008_gene3149	5.473e-121	391.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria,46QG9@74030|Roseovarius	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_875447_7	435908.IDSA_01260	5.254e-12	76.0	COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,2QF1S@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
CMS1_k127_875447_1	1288298.rosmuc_03374	7.76e-227	707.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,46PPZ@74030|Roseovarius	28211|Alphaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
CMS1_k127_875447_4	391613.RTM1035_11070	2.26e-161	511.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,46PHW@74030|Roseovarius	28211|Alphaproteobacteria	E	COG3741 N-formylglutamate amidohydrolase	MA20_06380	-	3.5.1.68	ko:K01458	ko00340,ko00630,map00340,map00630	-	R00525	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	FGase
CMS1_k127_875447_6	246200.SPO3284	4.103e-17	81.0	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,2UJAG@28211|Alphaproteobacteria,4NCRF@97050|Ruegeria	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS1_k127_875447_0	391613.RTM1035_14752	7.115e-241	751.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,46NX5@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0665 Glycine D-amino acid oxidases (deaminating)	MA20_00655	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_875447_2	391613.RTM1035_14757	7.085e-226	706.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TQN5@28211|Alphaproteobacteria,46NJZ@74030|Roseovarius	28211|Alphaproteobacteria	H	COG1541 Coenzyme F390 synthetase	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_875447_5	314271.RB2654_12064	9.766e-93	313.0	2E2MA@1|root,32XQG@2|Bacteria,1N2RU@1224|Proteobacteria,2UE7B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_875447_3	351016.RAZWK3B_04225	4.054e-166	525.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TT8N@28211|Alphaproteobacteria,2P180@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF1	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_890419_10	314264.ROS217_12591	3.621e-22	96.0	COG3326@1|root,COG3326@2|Bacteria,1NGR5@1224|Proteobacteria,2UJDY@28211|Alphaproteobacteria,46R0F@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
CMS1_k127_890419_7	1354722.JQLS01000008_gene2994	1.559e-76	258.0	28NNU@1|root,2ZBNZ@2|Bacteria,1RB1B@1224|Proteobacteria,2U5WI@28211|Alphaproteobacteria,46NDH@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_890419_0	351016.RAZWK3B_10567	1.541e-203	637.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TU94@28211|Alphaproteobacteria,2P1P8@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0332 3-oxoacyl- acyl-carrier-protein synthase III	fabH_2	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_890419_1	314264.ROS217_06840	6.225e-167	529.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,46NZ6@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	gyaR2	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00050,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_890419_8	314256.OG2516_14296	2.296e-53	190.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,2U9AH@28211|Alphaproteobacteria,2PEAK@252301|Oceanicola	28211|Alphaproteobacteria	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
CMS1_k127_890419_4	314264.ROS217_06830	1.341e-134	433.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,46Q6C@74030|Roseovarius	28211|Alphaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS1_k127_890419_6	391613.RTM1035_16377	7.488e-96	314.0	COG5465@1|root,COG5465@2|Bacteria,1REC1@1224|Proteobacteria,2U7UP@28211|Alphaproteobacteria,46P37@74030|Roseovarius	28211|Alphaproteobacteria	S	Putative bacterial sensory transduction regulator	MA20_05485	-	-	-	-	-	-	-	-	-	-	-	YbjN
CMS1_k127_890419_9	292414.TM1040_0621	1.935e-39	147.0	COG2960@1|root,COG2960@2|Bacteria,1N725@1224|Proteobacteria,2UFEP@28211|Alphaproteobacteria,4NCKP@97050|Ruegeria	28211|Alphaproteobacteria	S	Membrane fusogenic activity	MA20_05375	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
CMS1_k127_890419_3	1288298.rosmuc_03877	3.786e-157	499.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,46PUR@74030|Roseovarius	28211|Alphaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_890419_2	1288298.rosmuc_03876	1.807e-163	525.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2TRHW@28211|Alphaproteobacteria,46PYA@74030|Roseovarius	28211|Alphaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	MA20_05390	-	2.1.1.79	ko:K00574,ko:K18164	ko04714,map04714	-	-	-	ko00000,ko00001,ko01000,ko03029	-	-	-	Methyltransf_28
CMS1_k127_890419_5	1288298.rosmuc_03875	7.111e-131	420.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,46P2C@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS1_k127_890419_11	1354722.JQLS01000008_gene2899	6.142e-05	47.0	2AVIY@1|root,31MBJ@2|Bacteria,1PDJR@1224|Proteobacteria,2V3DS@28211|Alphaproteobacteria,46RC0@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_891360_13	1288298.rosmuc_01150	2.747e-08	58.0	COG5457@1|root,COG5457@2|Bacteria,1NHHX@1224|Proteobacteria,2UJ9Y@28211|Alphaproteobacteria,46RAK@74030|Roseovarius	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1127
CMS1_k127_891360_10	391613.RTM1035_06713	7.861e-92	303.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,46P1S@74030|Roseovarius	28211|Alphaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS1_k127_891360_8	314264.ROS217_22502	4.53e-98	330.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,46PRE@74030|Roseovarius	28211|Alphaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS1_k127_891360_0	314264.ROS217_22497	1.964e-198	620.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,46PFT@74030|Roseovarius	28211|Alphaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_891360_7	1354722.JQLS01000008_gene1967	5.094e-102	336.0	28JKE@1|root,2Z9D8@2|Bacteria,1MXFP@1224|Proteobacteria,2TRWA@28211|Alphaproteobacteria,46PET@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_891360_9	467661.RKLH11_610	8.061e-97	323.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,3ZG4A@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS1_k127_891360_11	1354722.JQLS01000008_gene1963	1.326e-49	181.0	2BWRJ@1|root,32V5S@2|Bacteria,1N3RJ@1224|Proteobacteria,2UDIV@28211|Alphaproteobacteria,46QX6@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_891360_2	1342299.Z947_1908	5.142e-169	533.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,3ZV48@60136|Sulfitobacter	28211|Alphaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_891360_4	1354722.JQLS01000008_gene1960	7.018e-134	433.0	COG1335@1|root,COG1335@2|Bacteria,1N48X@1224|Proteobacteria,2U17G@28211|Alphaproteobacteria,46PSA@74030|Roseovarius	28211|Alphaproteobacteria	Q	Related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_891360_3	1354722.JQLS01000008_gene1959	1.172e-136	441.0	COG0662@1|root,COG4977@1|root,COG0662@2|Bacteria,COG4977@2|Bacteria,1R8XV@1224|Proteobacteria,2U2RN@28211|Alphaproteobacteria,46PEC@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
CMS1_k127_891360_1	1354722.JQLS01000008_gene1958	2.008e-172	557.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,46PFD@74030|Roseovarius	28211|Alphaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
CMS1_k127_891360_12	314264.ROS217_22437	1.055e-41	157.0	2DMKE@1|root,32S6E@2|Bacteria,1N0IU@1224|Proteobacteria,2UC7Q@28211|Alphaproteobacteria,46R16@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3572)	MA20_36230	-	-	-	-	-	-	-	-	-	-	-	DUF3572
CMS1_k127_891360_6	391613.RTM1035_06773	1.067e-104	345.0	COG0546@1|root,COG0546@2|Bacteria,1RB0Z@1224|Proteobacteria,2U5DF@28211|Alphaproteobacteria,46NY3@74030|Roseovarius	28211|Alphaproteobacteria	S	HAD-superfamily hydrolase subfamily IA, variant	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_891360_5	391613.RTM1035_06778	1.595e-133	430.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2TT71@28211|Alphaproteobacteria,46QFQ@74030|Roseovarius	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_922081_1	1417296.U879_08165	1.011e-111	363.0	COG2816@1|root,COG2816@2|Bacteria,1MV1F@1224|Proteobacteria,2TTRT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1180 Pyruvate-formate lyase-activating enzyme	MA20_26535	-	1.3.7.1	ko:K20449	ko00760,ko01120,map00760,map01120	-	R03164	RC02422	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_922081_3	1121479.AUBS01000014_gene1167	3.022e-73	256.0	COG2122@1|root,COG2122@2|Bacteria,1MV9Z@1224|Proteobacteria,2TTG1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	ApbE
CMS1_k127_922081_2	571166.KI421509_gene1860	1.027e-102	336.0	2DBCJ@1|root,2Z8E3@2|Bacteria,1MXMX@1224|Proteobacteria,2U0E4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amino acid synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AA_synth
CMS1_k127_922081_0	1354722.JQLS01000008_gene2923	3.749e-206	646.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,46REG@74030|Roseovarius	28211|Alphaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_931652_2	985054.JQEZ01000001_gene2760	1.672e-28	116.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,4NC3V@97050|Ruegeria	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_931652_0	1354722.JQLS01000008_gene2444	1.6e-140	447.0	COG0745@1|root,COG0745@2|Bacteria,1MWER@1224|Proteobacteria,2TUCU@28211|Alphaproteobacteria,46PQ7@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_931652_1	314264.ROS217_04864	1.186e-115	375.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,46P2K@74030|Roseovarius	28211|Alphaproteobacteria	T	Sensory box histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_7,Response_reg
CMS1_k127_963034_6	314264.ROS217_08409	3.752e-06	49.0	COG0711@1|root,COG0711@2|Bacteria,1N0P5@1224|Proteobacteria,2U5DD@28211|Alphaproteobacteria,46NME@74030|Roseovarius	28211|Alphaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS1_k127_963034_1	314264.ROS217_08414	5.223e-70	241.0	COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,46Q8X@74030|Roseovarius	28211|Alphaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF2	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS1_k127_963034_5	1354722.JQLS01000008_gene3761	3.505e-36	139.0	COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UFPN@28211|Alphaproteobacteria,46R6H@74030|Roseovarius	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS1_k127_963034_0	1354722.JQLS01000008_gene3762	4.358e-147	469.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,46PY5@74030|Roseovarius	28211|Alphaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS1_k127_963034_3	89187.ISM_08900	3.521e-40	156.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria,46QYR@74030|Roseovarius	28211|Alphaproteobacteria	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
CMS1_k127_963034_2	314264.ROS217_08434	1.549e-65	226.0	COG0589@1|root,COG0589@2|Bacteria,1N13N@1224|Proteobacteria,2U9NZ@28211|Alphaproteobacteria,46QP5@74030|Roseovarius	28211|Alphaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_963034_4	391613.RTM1035_17172	6.579e-39	147.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,46QWB@74030|Roseovarius	28211|Alphaproteobacteria	K	Transcriptional Regulator, ArsR family	sdpR	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS1_k127_995293_0	1354722.JQLS01000008_gene1346	8.971e-261	816.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,46NM0@74030|Roseovarius	28211|Alphaproteobacteria	M	COG3264 Small-conductance mechanosensitive channel	kefA	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	DUF3772,MS_channel
CMS1_k127_995293_3	1354722.JQLS01000008_gene1347	5.274e-120	389.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2TRRW@28211|Alphaproteobacteria,46Q0E@74030|Roseovarius	28211|Alphaproteobacteria	S	metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	alaS2	GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
CMS1_k127_995293_2	1288298.rosmuc_03722	7.483e-174	552.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TQJJ@28211|Alphaproteobacteria,46QFW@74030|Roseovarius	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_995293_4	1530186.JQEY01000001_gene697	3.991e-10	60.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_995293_1	985054.JQEZ01000003_gene1289	4.292e-176	565.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4ND83@97050|Ruegeria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,Guanylate_cyc,SAM_2,TPR_12
## 3261 queries scanned
## Total time (seconds): 64.58308863639832
## Rate: 50.49 q/s