## Fri Nov  8 22:29:41 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS2_bin.58.fa -m mmseqs --itype genome -o CMS2_bin.58 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS2_bin.58 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS2_k127_1020086_1	742766.HMPREF9455_03179	1.502e-28	120.0	2A947@1|root,30Y8A@2|Bacteria,4NY1E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
CMS2_k127_1020086_0	1121890.AUDO01000003_gene1980	1.32e-30	128.0	2EI1D@1|root,33BSW@2|Bacteria,4NYPI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1028369_0	398720.MED217_09792	0.0	1089.0	COG4694@1|root,COG4694@2|Bacteria,4NFKW@976|Bacteroidetes,1HZHA@117743|Flavobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
CMS2_k127_1028369_12	1237149.C900_03182	3.705e-125	410.0	COG1472@1|root,COG1472@2|Bacteria,4NET8@976|Bacteroidetes,47P5P@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS2_k127_1028369_11	1237149.C900_03183	5.92e-127	419.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,47JKB@768503|Cytophagia	976|Bacteroidetes	M	PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS2_k127_1028369_1	688270.Celal_3660	5.801e-281	872.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia,1F8EV@104264|Cellulophaga	976|Bacteroidetes	H	COGs COG0129 Dihydroxyacid dehydratase phosphogluconate dehydratase	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS2_k127_1028369_2	1121930.AQXG01000004_gene2965	1.245e-272	848.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1IPTP@117747|Sphingobacteriia	976|Bacteroidetes	EH	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS2_k127_1028369_24	643867.Ftrac_1637	1.578e-60	214.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,47K1H@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM Acetolactate synthase, small subunit	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
CMS2_k127_1028369_4	1408473.JHXO01000004_gene215	1.338e-204	639.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,2FN0U@200643|Bacteroidia	976|Bacteroidetes	E	Ketol-acid reductoisomerase	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS2_k127_1028369_7	643867.Ftrac_1635	6.169e-188	595.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47MBE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS2_k127_1028369_20	641524.ADICYQ_4391	1.049e-103	344.0	COG0500@1|root,COG2226@2|Bacteria,4NJR0@976|Bacteroidetes,47PVG@768503|Cytophagia	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS2_k127_1028369_25	1237149.C900_03171	1.344e-55	199.0	COG2318@1|root,COG2318@2|Bacteria,4NU20@976|Bacteroidetes	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS2_k127_1028369_10	926562.Oweho_0685	2.084e-158	520.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HWMB@117743|Flavobacteriia,2PAJU@246874|Cryomorphaceae	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS2_k127_1028369_13	1408433.JHXV01000005_gene2538	6.037e-121	396.0	COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1HY76@117743|Flavobacteriia,2PBER@246874|Cryomorphaceae	976|Bacteroidetes	S	Thiazole biosynthesis protein ThiG	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS2_k127_1028369_8	616991.JPOO01000003_gene974	3.881e-180	573.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia,23GZ1@178469|Arenibacter	976|Bacteroidetes	L	helicase superfamily c-terminal domain	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_1028369_14	643867.Ftrac_0518	1.982e-118	387.0	COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia	976|Bacteroidetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS2_k127_1028369_19	1443665.JACA01000013_gene4271	9.943e-104	343.0	COG0500@1|root,COG2226@2|Bacteria,4NHAE@976|Bacteroidetes,1HYTJ@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS2_k127_1028369_17	313594.PI23P_09355	3.13e-110	360.0	COG3361@1|root,COG3361@2|Bacteria,4NITY@976|Bacteroidetes,1I0CJ@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
CMS2_k127_1028369_35	926562.Oweho_1003	4.464e-18	91.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBKY@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CMS2_k127_1028369_26	1237149.C900_00149	9.881e-47	188.0	COG4251@1|root,COG4251@2|Bacteria,4NIJY@976|Bacteroidetes,47NY0@768503|Cytophagia	976|Bacteroidetes	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
CMS2_k127_1028369_6	1313301.AUGC01000004_gene2372	1.14e-199	626.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CMS2_k127_1028369_3	1237149.C900_01742	5.968e-237	743.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,47JP7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS2_k127_1028369_23	1237149.C900_01741	1.563e-80	276.0	COG2846@1|root,COG2846@2|Bacteria,4NPQ7@976|Bacteroidetes,47PY2@768503|Cytophagia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin
CMS2_k127_1028369_27	1237149.C900_01740	7.964e-40	152.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,47QCM@768503|Cytophagia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS2_k127_1028369_22	1237149.C900_01739	1.353e-86	289.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,47JIG@768503|Cytophagia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS2_k127_1028369_21	1121859.KB890739_gene2190	7.273e-90	303.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,47JPF@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS2_k127_1028369_30	1279009.ADICEAN_00639	1.634e-29	134.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NN9A@976|Bacteroidetes,47QQI@768503|Cytophagia	976|Bacteroidetes	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
CMS2_k127_1028369_32	1408433.JHXV01000010_gene565	7.117e-28	129.0	COG2208@1|root,COG2208@2|Bacteria,4PPWM@976|Bacteroidetes,1IKWE@117743|Flavobacteriia,2PBIK@246874|Cryomorphaceae	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
CMS2_k127_1028369_31	1305737.JAFX01000001_gene3008	5.024e-28	114.0	2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,47S69@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1028369_15	762903.Pedsa_2109	3.882e-111	367.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1IR2F@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
CMS2_k127_1028369_28	1237149.C900_03184	4.646e-39	151.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS2_k127_1028369_16	471854.Dfer_4873	1.114e-110	361.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS2_k127_1028369_18	1237149.C900_04921	9.502e-109	361.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,47MKU@768503|Cytophagia	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS2_k127_1028369_33	1453498.LG45_01575	2.184e-23	104.0	2C0T5@1|root,32RSX@2|Bacteria,4NQX0@976|Bacteroidetes,1I3AM@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS2_k127_1028369_34	1210884.HG799463_gene10144	8.747e-22	110.0	28HEJ@1|root,2Z7QZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185,DUF5005
CMS2_k127_1028369_36	1353276.JADR01000007_gene1454	8.395e-17	81.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,4NECV@976|Bacteroidetes,1HXAD@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
CMS2_k127_1028369_5	643867.Ftrac_1929	9.831e-203	640.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS2_k127_1028369_9	1237149.C900_01760	1.864e-164	533.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,47JYH@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
CMS2_k127_1028369_29	1237149.C900_01761	1.868e-38	148.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,47Q5G@768503|Cytophagia	976|Bacteroidetes	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS2_k127_1031708_18	1120965.AUBV01000012_gene1394	1.575e-22	101.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
CMS2_k127_1031708_10	1317122.ATO12_19400	7.918e-84	289.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,2YK2V@290174|Aquimarina	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
CMS2_k127_1031708_19	269798.CHU_2239	1.675e-20	94.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,47R8R@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_1031708_12	1237149.C900_03320	4.383e-79	268.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,47KYT@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the PRA-CH family	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
CMS2_k127_1031708_6	1237149.C900_03321	1.15e-114	374.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,47K9T@768503|Cytophagia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_1031708_13	929562.Emtol_2179	2.637e-77	265.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,47M7D@768503|Cytophagia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_1031708_11	1279009.ADICEAN_01475	1.141e-80	272.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,47P9A@768503|Cytophagia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS2_k127_1031708_2	1123035.ARLA01000027_gene470	9.74e-163	519.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia,4C3GC@83612|Psychroflexus	976|Bacteroidetes	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
CMS2_k127_1031708_5	1168289.AJKI01000011_gene559	1.047e-114	379.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,2FMFQ@200643|Bacteroidia,3XJIR@558415|Marinilabiliaceae	976|Bacteroidetes	E	Allinase	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_1031708_1	1122971.BAME01000001_gene32	1.069e-164	527.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,2FMY9@200643|Bacteroidia,22WQW@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS2_k127_1031708_7	1237149.C900_03327	1.233e-113	372.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,47M8W@768503|Cytophagia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS2_k127_1031708_16	313606.M23134_04185	5.233e-32	130.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_1031708_8	1121939.L861_06035	1.063e-102	357.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQAF@1236|Gammaproteobacteria,1XI9H@135619|Oceanospirillales	135619|Oceanospirillales	NT	Nitrate and nitrite sensing	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,NIT
CMS2_k127_1031708_15	1173020.Cha6605_0959	3.613e-38	153.0	COG0508@1|root,COG0508@2|Bacteria,1G4MH@1117|Cyanobacteria	1117|Cyanobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
CMS2_k127_1031708_3	1341181.FLJC2902T_10900	1.214e-159	518.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia,2NT9U@237|Flavobacterium	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS2_k127_1031708_4	1237149.C900_03328	6.974e-134	433.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_1031708_9	1121904.ARBP01000010_gene2429	1.517e-95	314.0	COG0521@1|root,COG0521@2|Bacteria,4PIS5@976|Bacteroidetes,47KA4@768503|Cytophagia	976|Bacteroidetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS2_k127_1031708_14	1237149.C900_03331	2.876e-46	173.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1031708_17	929556.Solca_2577	1.055e-28	116.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS2_k127_1031708_0	1237149.C900_03333	2.749e-231	726.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,47MAW@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
CMS2_k127_1031708_20	1123276.KB893268_gene4987	4.62e-06	48.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,47TY5@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
CMS2_k127_1041467_17	1305737.JAFX01000001_gene1565	5.984e-71	249.0	28NS9@1|root,2ZBRA@2|Bacteria,4NJGG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1041467_1	643867.Ftrac_0656	8.111e-242	756.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,47JPR@768503|Cytophagia	976|Bacteroidetes	E	PFAM Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CMS2_k127_1041467_16	1121904.ARBP01000032_gene2017	1.952e-108	364.0	COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,47N41@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M20/M25/M40	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_1041467_23	1408433.JHXV01000001_gene994	1.014e-29	129.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1041467_18	660470.Theba_2126	3.639e-63	237.0	COG0405@1|root,COG0405@2|Bacteria,2GCYN@200918|Thermotogae	200918|Thermotogae	M	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS2_k127_1041467_15	1237149.C900_03561	7.65e-115	375.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,47M8B@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS2_k127_1041467_10	556267.HWAG_00947	2.057e-159	509.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS2_k127_1041467_9	1121104.AQXH01000001_gene1740	1.097e-164	524.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1IR9A@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CMS2_k127_1041467_21	1158345.JNLL01000001_gene1710	8.903e-45	168.0	COG1778@1|root,COG1778@2|Bacteria,2G45K@200783|Aquificae	200783|Aquificae	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
CMS2_k127_1041467_0	1237149.C900_03559	2.947e-270	854.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47JRC@768503|Cytophagia	976|Bacteroidetes	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS2_k127_1041467_24	1124780.ANNU01000040_gene402	2.435e-05	51.0	2E8WY@1|root,33373@2|Bacteria,4NV40@976|Bacteroidetes,47RXW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1041467_4	1237149.C900_04771	1.084e-206	651.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,47KX5@768503|Cytophagia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1041467_8	1237149.C900_04772	1.191e-169	544.0	COG0025@1|root,COG0025@2|Bacteria,4NFHG@976|Bacteroidetes,47KAJ@768503|Cytophagia	976|Bacteroidetes	P	NhaP-type Na H and K H	nhaP	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS2_k127_1041467_19	760192.Halhy_1516	1.89e-60	218.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1ITNU@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_1041467_6	1121904.ARBP01000019_gene2790	3.409e-171	550.0	COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,47NFV@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
CMS2_k127_1041467_11	880070.Cycma_4829	7.422e-150	496.0	COG4251@1|root,COG4251@2|Bacteria,4NN2W@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
CMS2_k127_1041467_12	388413.ALPR1_14299	9.371e-131	420.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,47JN8@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS2_k127_1041467_22	1237149.C900_05671	1.536e-35	143.0	2CYF8@1|root,32T43@2|Bacteria,4NUAU@976|Bacteroidetes,47RBY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1041467_2	1237149.C900_05672	3.167e-228	710.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS2_k127_1041467_5	643867.Ftrac_0931	1.496e-174	567.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS2_k127_1041467_7	1237149.C900_00265	2.485e-170	541.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,47JZ3@768503|Cytophagia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS2_k127_1041467_3	1237149.C900_00263	6.203e-221	720.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	fpp2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
CMS2_k127_1041467_14	1237149.C900_00262	4.912e-117	386.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,47M8U@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS2_k127_1041467_20	1237149.C900_00261	1.103e-59	216.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia	976|Bacteroidetes	S	PFAM PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
CMS2_k127_1041467_13	1237149.C900_00260	2.181e-119	406.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,47JC7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1062638_0	1237149.C900_00005	1.707e-266	828.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,47K5S@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS2_k127_1062638_1	1121859.KB890739_gene2831	3.74e-16	82.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,47KAA@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1063264_7	865937.Gilli_0446	1.141e-87	293.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_1063264_0	760192.Halhy_2533	5.736e-293	906.0	COG2303@1|root,COG2303@2|Bacteria,4NHJT@976|Bacteroidetes,1IRDW@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS2_k127_1063264_5	1454007.JAUG01000047_gene512	3.687e-134	436.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1063264_6	313596.RB2501_11517	1.788e-108	359.0	COG0657@1|root,COG0657@2|Bacteria,4PKKH@976|Bacteroidetes,1HX7Y@117743|Flavobacteriia	976|Bacteroidetes	I	Dienelactone hydrolase family	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
CMS2_k127_1063264_1	1121904.ARBP01000008_gene3221	7.337e-261	807.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_1063264_10	700598.Niako_6252	8.089e-53	191.0	2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,1ISA1@117747|Sphingobacteriia	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_1063264_8	1123057.P872_14390	9.25e-68	237.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,47NRI@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
CMS2_k127_1063264_2	1121904.ARBP01000006_gene3716	2.549e-239	757.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
CMS2_k127_1063264_4	1121904.ARBP01000001_gene5944	2.568e-183	585.0	COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,47JW2@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
CMS2_k127_1063264_9	1185876.BN8_02803	1.703e-66	234.0	COG0398@1|root,COG0398@2|Bacteria,4NHA2@976|Bacteroidetes,47S54@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
CMS2_k127_1063264_13	616991.JPOO01000003_gene2483	1.963e-05	47.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1I031@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
CMS2_k127_1063264_11	1519464.HY22_04380	2.275e-42	156.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_1063264_12	1121481.AUAS01000007_gene1100	1.947e-29	121.0	COG4679@1|root,COG4679@2|Bacteria,4NPPR@976|Bacteroidetes,47Q24@768503|Cytophagia	976|Bacteroidetes	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
CMS2_k127_1063264_3	1267535.KB906767_gene316	9.027e-218	695.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3NT@57723|Acidobacteria,2JIBK@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
CMS2_k127_1069386_40	1216967.L100_15575	3.307e-65	236.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1HWQZ@117743|Flavobacteriia,34PKV@308865|Elizabethkingia	976|Bacteroidetes	S	Phosphotransferase enzyme family	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
CMS2_k127_1069386_26	1454007.JAUG01000084_gene3861	4.812e-101	337.0	COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,1IPJU@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
CMS2_k127_1069386_3	1121904.ARBP01000005_gene4668	2.585e-317	978.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,47MV2@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS2_k127_1069386_55	1237149.C900_04701	5.994e-27	127.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_1069386_58	1349785.BAUG01000030_gene1743	4.449e-06	59.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1069386_24	1237149.C900_05556	7.746e-107	359.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,47K8K@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
CMS2_k127_1069386_11	471854.Dfer_4273	4.806e-174	550.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,47KV9@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
CMS2_k127_1069386_10	1237149.C900_05559	1.985e-174	562.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,47MQT@768503|Cytophagia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	aldH	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS2_k127_1069386_17	509635.N824_24465	3.756e-128	415.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1IQRX@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS2_k127_1069386_50	1237149.C900_03869	4.273e-50	186.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,47Q4T@768503|Cytophagia	976|Bacteroidetes	C	PFAM WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
CMS2_k127_1069386_0	643867.Ftrac_1710	0.0	1373.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,47JFM@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS2_k127_1069386_37	1124780.ANNU01000030_gene1180	3.392e-66	230.0	COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,47N9Z@768503|Cytophagia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS2_k127_1069386_20	1237149.C900_05061	4.113e-117	380.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,47JX6@768503|Cytophagia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS2_k127_1069386_27	1288963.ADIS_1373	6.834e-99	327.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,47MP4@768503|Cytophagia	976|Bacteroidetes	D	PFAM ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS2_k127_1069386_47	1237149.C900_05058	2.54e-56	203.0	COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,47P7T@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_1069386_36	1237149.C900_00607	7.851e-67	237.0	2DN4I@1|root,32VGS@2|Bacteria,4NNY4@976|Bacteroidetes,47RGS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
CMS2_k127_1069386_2	1237149.C900_00608	5e-324	1008.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1069386_28	1120966.AUBU01000001_gene1208	8.49e-98	329.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,47JJP@768503|Cytophagia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
CMS2_k127_1069386_12	435591.BDI_0362	5.919e-173	557.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,2FMAW@200643|Bacteroidia,22W26@171551|Porphyromonadaceae	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS2_k127_1069386_41	643867.Ftrac_0647	4.042e-65	252.0	COG3850@1|root,COG3850@2|Bacteria,4NHQZ@976|Bacteroidetes,47PHP@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_4
CMS2_k127_1069386_6	1237149.C900_05195	2.127e-280	885.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,47K5C@768503|Cytophagia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS2_k127_1069386_7	1237149.C900_05208	6.644e-258	812.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,47M2A@768503|Cytophagia	976|Bacteroidetes	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS2_k127_1069386_31	153721.MYP_2349	1.693e-92	314.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,47JI4@768503|Cytophagia	976|Bacteroidetes	E	PFAM GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
CMS2_k127_1069386_57	1392498.JQLH01000001_gene2120	4.741e-09	66.0	COG3637@1|root,COG3637@2|Bacteria,4NEPJ@976|Bacteroidetes,1HYA1@117743|Flavobacteriia,2PI45@252356|Maribacter	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS2_k127_1069386_43	1237149.C900_05222	2.534e-63	220.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,47PY1@768503|Cytophagia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS2_k127_1069386_53	1237149.C900_05223	3.148e-39	147.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,47R23@768503|Cytophagia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS2_k127_1069386_49	1237149.C900_05224	3.634e-50	181.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS2_k127_1069386_29	1237149.C900_05228	3.385e-96	324.0	COG1196@1|root,COG1196@2|Bacteria,4NHAC@976|Bacteroidetes,47MGD@768503|Cytophagia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	-
CMS2_k127_1069386_38	411154.GFO_2405	1.379e-65	230.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,1I1JP@117743|Flavobacteriia	976|Bacteroidetes	Q	SAM-dependent	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
CMS2_k127_1069386_46	1237149.C900_05946	1.448e-56	206.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,47N8Y@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS2_k127_1069386_48	1237149.C900_05945	1.082e-51	186.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,47PP3@768503|Cytophagia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS2_k127_1069386_30	1120968.AUBX01000014_gene2383	7.563e-94	312.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,47JRB@768503|Cytophagia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS2_k127_1069386_16	1237149.C900_05943	7.987e-131	432.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,47JH7@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS2_k127_1069386_33	1317122.ATO12_20145	4.446e-85	287.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia,2YH3Y@290174|Aquimarina	976|Bacteroidetes	E	Dihydrodipicolinate reductase, C-terminus	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS2_k127_1069386_51	1237149.C900_05941	1.805e-48	180.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,47RVI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1069386_21	1237149.C900_05940	1.689e-115	379.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,47K9I@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS2_k127_1069386_18	1124780.ANNU01000037_gene130	6.588e-125	404.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,47JM3@768503|Cytophagia	976|Bacteroidetes	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS2_k127_1069386_9	1237149.C900_05937	3.44e-183	591.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,47KF7@768503|Cytophagia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS2_k127_1069386_5	1237149.C900_05936	1.33e-296	915.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,47KXM@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS2_k127_1069386_8	1237149.C900_05056	1.184e-206	651.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,47KFG@768503|Cytophagia	976|Bacteroidetes	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS2_k127_1069386_44	1237149.C900_05057	3.218e-63	224.0	COG0457@1|root,COG0457@2|Bacteria,4NSYY@976|Bacteroidetes,47R4Q@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_2,TPR_8
CMS2_k127_1069386_39	1048983.EL17_02510	3.209e-65	230.0	COG2135@1|root,COG2135@2|Bacteria,4NKPN@976|Bacteroidetes,47MR7@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS2_k127_1069386_13	1237149.C900_03865	4.301e-152	504.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,47JA7@768503|Cytophagia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1069386_14	1237149.C900_03745	6.564e-147	471.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,47KNQ@768503|Cytophagia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
CMS2_k127_1069386_19	643867.Ftrac_3721	3.843e-119	388.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS2_k127_1069386_22	880073.Calab_0643	3.664e-114	378.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS2_k127_1069386_15	1453498.LG45_01110	2.153e-131	427.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
CMS2_k127_1069386_42	743722.Sph21_3891	1.757e-63	226.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1IRTX@117747|Sphingobacteriia	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
CMS2_k127_1069386_32	1124780.ANNU01000054_gene3530	9.819e-92	308.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,47JQJ@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
CMS2_k127_1069386_4	1237149.C900_05721	4.786e-307	955.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS2_k127_1069386_52	1237149.C900_05720	3.261e-44	163.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS2_k127_1069386_45	761193.Runsl_3149	1.562e-60	218.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
CMS2_k127_1069386_56	1124780.ANNU01000003_gene1438	4.374e-13	74.0	COG0745@1|root,COG0745@2|Bacteria,4NSD3@976|Bacteroidetes,47R2H@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_1069386_35	1237149.C900_04209	1.382e-76	269.0	COG2148@1|root,COG2148@2|Bacteria,4NHSV@976|Bacteroidetes,47M3N@768503|Cytophagia	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Response_reg
CMS2_k127_1069386_23	1237149.C900_04208	3.629e-112	374.0	COG1215@1|root,COG1215@2|Bacteria,4NEM5@976|Bacteroidetes,47MUH@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
CMS2_k127_1069386_34	153721.MYP_573	2.708e-82	282.0	COG1216@1|root,COG1216@2|Bacteria,4NEJB@976|Bacteroidetes,47MPS@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS2_k127_1069386_25	880070.Cycma_5055	2.19e-103	348.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,47KRN@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS2_k127_1069386_1	1237149.C900_04204	0.0	1290.0	COG3291@1|root,COG4099@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG4932@2|Bacteria,4NP7H@976|Bacteroidetes,47XCB@768503|Cytophagia	976|Bacteroidetes	M	Immunoglobulin like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1088422_12	1120965.AUBV01000012_gene1394	1.166e-07	54.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
CMS2_k127_1088422_10	641524.ADICYQ_5455	4.022e-39	148.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,47R8R@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_1088422_1	1279009.ADICEAN_02987	2.053e-289	900.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,47NPV@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS2_k127_1088422_2	649349.Lbys_3010	6.151e-181	571.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,47MC3@768503|Cytophagia	976|Bacteroidetes	G	fructose-bisphosphate aldolase, class II, yeast E. coli subtype	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CMS2_k127_1088422_8	1313301.AUGC01000005_gene197	2.023e-51	188.0	COG1060@1|root,COG1060@2|Bacteria	2|Bacteria	H	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
CMS2_k127_1088422_5	1121904.ARBP01000018_gene2606	2.341e-72	264.0	COG4191@1|root,COG4191@2|Bacteria,4NE4T@976|Bacteroidetes,47K96@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_1088422_9	1121904.ARBP01000009_gene4223	6.321e-40	153.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,4NF1F@976|Bacteroidetes,47MSJ@768503|Cytophagia	976|Bacteroidetes	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
CMS2_k127_1088422_6	329726.AM1_3543	6.064e-70	258.0	COG4325@1|root,COG4325@2|Bacteria,1GB6R@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1088422_3	319236.JCM19294_1900	9.404e-155	503.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1HY6K@117743|Flavobacteriia,3HKVR@363408|Nonlabens	976|Bacteroidetes	S	Domain of unknown function (DUF3520)	yfbK	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,Plug,VWA,vWF_A
CMS2_k127_1088422_4	1237149.C900_01635	3.947e-149	482.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS2_k127_1088422_11	1454007.JAUG01000002_gene2940	7.038e-13	72.0	2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,1IUG5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1088422_7	1237149.C900_01641	6.855e-56	200.0	COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,47QDX@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	fecI	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS2_k127_1088422_0	1237149.C900_01647	0.0	1634.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,47NAM@768503|Cytophagia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CMS2_k127_1106359_1	1048983.EL17_06380	5.911e-318	1003.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y6D@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CMS2_k127_1106359_5	1048983.EL17_06385	4.908e-170	554.0	COG1395@1|root,COG1395@2|Bacteria,4PMSD@976|Bacteroidetes,47Y95@768503|Cytophagia	976|Bacteroidetes	K	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_1106359_2	1123057.P872_16125	8.239e-292	930.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47JJ5@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_1106359_0	643867.Ftrac_2065	0.0	1066.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,47M9X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
CMS2_k127_1106359_6	1444711.CCJF01000003_gene87	4.649e-143	458.0	COG0462@1|root,COG0462@2|Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
CMS2_k127_1106359_3	1249975.JQLP01000001_gene2922	5.555e-211	666.0	COG0213@1|root,COG0213@2|Bacteria,4NFVB@976|Bacteroidetes,1HZ41@117743|Flavobacteriia	976|Bacteroidetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS2_k127_1106359_4	1122176.KB903533_gene2310	1.251e-208	658.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IWDU@117747|Sphingobacteriia	976|Bacteroidetes	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CMS2_k127_1106359_7	1237149.C900_05282	5.434e-118	385.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,47P1Y@768503|Cytophagia	976|Bacteroidetes	K	PFAM ATP cone domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
CMS2_k127_1106359_8	880070.Cycma_4573	1.851e-19	88.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47UID@768503|Cytophagia	976|Bacteroidetes	T	COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_1134909_96	1227739.Hsw_2932	5.057e-69	248.0	COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,47KUG@768503|Cytophagia	976|Bacteroidetes	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS2_k127_1134909_70	457424.BFAG_03289	4.146e-100	346.0	COG2843@1|root,COG2843@2|Bacteria,4NGD2@976|Bacteroidetes,2FQ0M@200643|Bacteroidia,4AMPS@815|Bacteroidaceae	976|Bacteroidetes	M	Bacterial capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS2_k127_1134909_112	1122176.KB903609_gene5261	8.579e-50	186.0	COG1030@1|root,COG1030@2|Bacteria,4PN0T@976|Bacteroidetes,1ITG9@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
CMS2_k127_1134909_61	313603.FB2170_09311	8.676e-110	365.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1HYFP@117743|Flavobacteriia,2PGPN@252356|Maribacter	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS2_k127_1134909_36	999419.HMPREF1077_00659	1.463e-171	556.0	COG0436@1|root,COG1395@1|root,COG0436@2|Bacteria,COG1395@2|Bacteria,4NEA1@976|Bacteroidetes,2FP97@200643|Bacteroidia,22XUH@171551|Porphyromonadaceae	976|Bacteroidetes	K	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_1134909_2	880070.Cycma_4433	0.0	1156.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1134909_64	1121481.AUAS01000008_gene2941	1.077e-104	347.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,47M8V@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_1134909_37	1237149.C900_05597	2.834e-169	554.0	COG1361@1|root,COG1361@2|Bacteria,4PKPA@976|Bacteroidetes	976|Bacteroidetes	M	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
CMS2_k127_1134909_51	1237149.C900_05598	5.006e-132	433.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,47KKP@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_1134909_135	1279009.ADICEAN_00334	9.164e-15	82.0	2EVP8@1|root,334YW@2|Bacteria,4NX4R@976|Bacteroidetes,47SHG@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
CMS2_k127_1134909_118	1237149.C900_05600	9.025e-39	151.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,47QS1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
CMS2_k127_1134909_43	1237149.C900_05601	1.415e-146	469.0	COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,47XY0@768503|Cytophagia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_1134909_79	153721.MYP_3391	9.822e-89	302.0	COG1215@1|root,COG1215@2|Bacteria,4PKBU@976|Bacteroidetes,47MX1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
CMS2_k127_1134909_56	1237149.C900_05462	7.092e-119	412.0	COG4251@1|root,COG4251@2|Bacteria,4PM7A@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HNOBA,HisKA,PAS_3,PAS_9,Response_reg
CMS2_k127_1134909_85	1237149.C900_04861	4.515e-80	273.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
CMS2_k127_1134909_4	1237149.C900_04864	0.0	1083.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,47JMH@768503|Cytophagia	976|Bacteroidetes	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS2_k127_1134909_88	1237149.C900_04865	1.434e-75	259.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,47PZX@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
CMS2_k127_1134909_18	1124780.ANNU01000084_gene1352	1.785e-218	683.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS2_k127_1134909_134	203119.Cthe_2115	7.306e-16	80.0	COG0011@1|root,COG0011@2|Bacteria,1VBWM@1239|Firmicutes,25DPD@186801|Clostridia,3WJSB@541000|Ruminococcaceae	186801|Clostridia	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
CMS2_k127_1134909_82	1124780.ANNU01000045_gene2287	9.959e-81	272.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,47Q0M@768503|Cytophagia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS2_k127_1134909_83	643867.Ftrac_0552	1.308e-80	273.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,47NVP@768503|Cytophagia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS2_k127_1134909_39	1237149.C900_01650	5.332e-160	508.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,47MGR@768503|Cytophagia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS2_k127_1134909_40	1237149.C900_01113	4.169e-154	500.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS2_k127_1134909_106	929703.KE386491_gene3092	3.042e-55	207.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,47JZE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS2_k127_1134909_72	1237149.C900_03672	7.018e-99	325.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,47JCE@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_1134909_86	1237149.C900_03670	9.338e-78	265.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,47KEA@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS2_k127_1134909_132	487796.Flav2ADRAFT_0033	5.824e-21	94.0	2BZQB@1|root,32Y98@2|Bacteria,4NVDQ@976|Bacteroidetes,1I5G0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1134909_129	869213.JCM21142_52233	3.867e-27	111.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,47RX4@768503|Cytophagia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_1134909_68	980584.AFPB01000177_gene943	2.135e-102	344.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia,406PR@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_1134909_58	1237149.C900_05578	4.522e-116	383.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS2_k127_1134909_13	1288963.ADIS_2100	1.217e-245	787.0	COG2010@1|root,COG2010@2|Bacteria,4NFP6@976|Bacteroidetes,47JRP@768503|Cytophagia	976|Bacteroidetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,PSCyt1,PSCyt2,PSD1
CMS2_k127_1134909_14	1121859.KB890739_gene2783	2.311e-241	753.0	COG3119@1|root,COG3119@2|Bacteria,4NGVK@976|Bacteroidetes,47K11@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS2_k127_1134909_69	1121904.ARBP01000013_gene358	9.182e-102	348.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
CMS2_k127_1134909_97	1322246.BN4_12789	2.135e-65	246.0	COG0642@1|root,COG0715@1|root,COG0715@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	fgrL	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,PocR,Response_reg,Y_Y_Y
CMS2_k127_1134909_15	1237149.C900_05255	1.935e-230	750.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
CMS2_k127_1134909_3	1237149.C900_05254	0.0	1108.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia	976|Bacteroidetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_1134909_66	1237149.C900_05253	1.213e-103	340.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_1134909_92	1237149.C900_05252	2.046e-71	247.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS2_k127_1134909_21	1121011.AUCB01000034_gene885	4.793e-215	694.0	COG2133@1|root,COG2133@2|Bacteria,4NH6W@976|Bacteroidetes,1I07N@117743|Flavobacteriia,23GBN@178469|Arenibacter	976|Bacteroidetes	G	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_1134909_41	1237149.C900_03102	5.996e-152	484.0	COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,47N4V@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_1134909_45	1237149.C900_02365	8.486e-144	465.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,47JGI@768503|Cytophagia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS2_k127_1134909_55	1237149.C900_02366	4.206e-124	407.0	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,47KFQ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	ko:K13004	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CMS2_k127_1134909_98	1237149.C900_02367	6.06e-64	223.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,47PQR@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS2_k127_1134909_107	1237149.C900_02368	1.887e-53	197.0	COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,47Q04@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
CMS2_k127_1134909_23	1237149.C900_02369	2.278e-211	680.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
CMS2_k127_1134909_90	153721.MYP_4323	5.949e-74	256.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,47PBY@768503|Cytophagia	976|Bacteroidetes	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS2_k127_1134909_73	1237149.C900_02371	2.09e-97	328.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,47M93@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
CMS2_k127_1134909_31	1237149.C900_02372	1.084e-175	561.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,47M8A@768503|Cytophagia	976|Bacteroidetes	NU	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS2_k127_1134909_49	1237149.C900_02373	8.9e-137	437.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,47MRM@768503|Cytophagia	976|Bacteroidetes	S	PFAM (2R)-phospho-3-sulfolactate synthase ComA	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
CMS2_k127_1134909_65	382464.ABSI01000005_gene1210	9.739e-104	345.0	COG2035@1|root,COG2035@2|Bacteria,46XE7@74201|Verrucomicrobia,2IVMZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF368
CMS2_k127_1134909_81	643867.Ftrac_2672	2.617e-83	284.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,47JZN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
CMS2_k127_1134909_6	1237149.C900_02379	0.0	1065.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,47KBV@768503|Cytophagia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS2_k127_1134909_71	1392489.JPOL01000002_gene1757	9.938e-100	338.0	COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,1I0YG@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
CMS2_k127_1134909_115	1237149.C900_04692	1.667e-44	175.0	COG1670@1|root,COG1670@2|Bacteria,4NQ6A@976|Bacteroidetes,47QQA@768503|Cytophagia	976|Bacteroidetes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_1134909_91	1408433.JHXV01000017_gene1562	1.731e-73	255.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,1HZGI@117743|Flavobacteriia,2PAPR@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_1134909_44	388413.ALPR1_00680	7.177e-146	471.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Phytase-like
CMS2_k127_1134909_26	388413.ALPR1_00675	4.239e-203	652.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase
CMS2_k127_1134909_57	1121904.ARBP01000001_gene5717	6.312e-117	386.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,47NK3@768503|Cytophagia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CMS2_k127_1134909_20	1237149.C900_02263	4.427e-215	675.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,47N6V@768503|Cytophagia	976|Bacteroidetes	U	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS2_k127_1134909_24	1124780.ANNU01000047_gene2265	2.254e-209	678.0	COG2304@1|root,COG2304@2|Bacteria,4PP24@976|Bacteroidetes	976|Bacteroidetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
CMS2_k127_1134909_89	1124780.ANNU01000047_gene2266	5.342e-74	266.0	29Q0T@1|root,30AZ9@2|Bacteria,4NP77@976|Bacteroidetes	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS2_k127_1134909_130	153721.MYP_1630	9.953e-23	102.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47RS5@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS2_k127_1134909_9	153721.MYP_3734	7.3e-295	913.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,47KWA@768503|Cytophagia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_1134909_33	1123248.KB893326_gene1386	2.461e-174	552.0	COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,1IQIB@117747|Sphingobacteriia	976|Bacteroidetes	C	Thiazole biosynthesis protein ThiH	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
CMS2_k127_1134909_52	1131812.JQMS01000001_gene1305	3.108e-127	410.0	COG2022@1|root,COG2022@2|Bacteria,4NDWY@976|Bacteroidetes,1HZ0A@117743|Flavobacteriia,2NSH0@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS2_k127_1134909_87	1492738.FEM21_02930	6.131e-76	259.0	COG0352@1|root,COG0352@2|Bacteria,4NNFB@976|Bacteroidetes,1I1XE@117743|Flavobacteriia,2NTFJ@237|Flavobacterium	976|Bacteroidetes	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
CMS2_k127_1134909_95	153721.MYP_4583	2.78e-69	243.0	COG0351@1|root,COG0351@2|Bacteria,4NE0F@976|Bacteroidetes,47PMU@768503|Cytophagia	976|Bacteroidetes	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS2_k127_1134909_119	1408813.AYMG01000004_gene4580	9.655e-37	146.0	COG0352@1|root,COG0352@2|Bacteria,4NRDR@976|Bacteroidetes,1ISZ9@117747|Sphingobacteriia	976|Bacteroidetes	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS2_k127_1134909_5	1270196.JCKI01000005_gene2999	0.0	1077.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,1INSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS2_k127_1134909_136	362418.IW19_15775	2.013e-14	76.0	COG2104@1|root,COG2104@2|Bacteria,4NX2F@976|Bacteroidetes,1I6BK@117743|Flavobacteriia,2NXJ3@237|Flavobacterium	976|Bacteroidetes	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS2_k127_1134909_142	756272.Plabr_0892	1.915e-08	55.0	COG3119@1|root,COG3119@2|Bacteria,2J1QG@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_1134909_138	313628.LNTAR_05664	4.284e-11	65.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_1134909_19	1288963.ADIS_0480	2.868e-215	688.0	COG2133@1|root,COG3241@1|root,COG2133@2|Bacteria,COG3241@2|Bacteria,4NEMM@976|Bacteroidetes,47KGJ@768503|Cytophagia	976|Bacteroidetes	CG	PFAM Blue (type 1) copper domain	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS2_k127_1134909_48	929703.KE386491_gene3555	2.38e-139	463.0	COG2010@1|root,COG2010@2|Bacteria,4NEJ0@976|Bacteroidetes,47JEV@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PA14
CMS2_k127_1134909_126	1123278.KB893450_gene6227	2.146e-29	121.0	COG4680@1|root,COG4680@2|Bacteria,4NSID@976|Bacteroidetes,47V89@768503|Cytophagia	976|Bacteroidetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HigB_toxin
CMS2_k127_1134909_77	485918.Cpin_1595	2.342e-91	314.0	COG2067@1|root,COG2067@2|Bacteria,4NG1B@976|Bacteroidetes,1IWK5@117747|Sphingobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CMS2_k127_1134909_140	655815.ZPR_1922	3.788e-10	63.0	2E4IE@1|root,32ZDH@2|Bacteria,4NUR6@976|Bacteroidetes,1I59Y@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CMS2_k127_1134909_84	655815.ZPR_1921	3.184e-80	277.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HWM7@117743|Flavobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS2_k127_1134909_139	984262.SGRA_2186	1.291e-10	68.0	COG0526@1|root,COG0526@2|Bacteria,4NQ50@976|Bacteroidetes	976|Bacteroidetes	CO	Thiol-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CMS2_k127_1134909_30	1123248.KB893370_gene5050	4.017e-176	564.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,1IPYV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
CMS2_k127_1134909_42	1121012.AUKX01000011_gene2333	1.92e-149	481.0	COG0673@1|root,COG0673@2|Bacteria,4NFGY@976|Bacteroidetes,1HZUQ@117743|Flavobacteriia,23H27@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1134909_144	195253.Syn6312_1199	9.587e-07	55.0	2DNRM@1|root,32YT2@2|Bacteria,1G8FD@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
CMS2_k127_1134909_131	760192.Halhy_4114	2.853e-21	95.0	2C5EY@1|root,31EA9@2|Bacteria,4NYA8@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
CMS2_k127_1134909_60	929713.NIASO_02035	2.391e-112	374.0	COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes,1IPNI@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS2_k127_1134909_54	1250005.PHEL85_1899	2.991e-126	415.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia	976|Bacteroidetes	V	transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS2_k127_1134909_62	1123037.AUDE01000006_gene1129	1.711e-107	353.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_1134909_59	742767.HMPREF9456_01125	1.024e-112	372.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,2FWZE@200643|Bacteroidia,22W0S@171551|Porphyromonadaceae	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_1134909_104	1121896.JMLU01000018_gene2883	1.993e-59	216.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes,1I071@117743|Flavobacteriia,2NVFX@237|Flavobacterium	976|Bacteroidetes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_1134909_120	929703.KE386491_gene1375	6.019e-35	149.0	COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,47NS6@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_1134909_117	1120951.AUBG01000005_gene2194	7.926e-41	158.0	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,1HZ1F@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_1134909_141	1124780.ANNU01000061_gene908	7.621e-10	71.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	ko:K16076,ko:K18093	ko01501,ko02020,map01501,map02020	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.1.4,1.B.1.1.5,1.B.25.1.1	-	-	OprD,Porin_4
CMS2_k127_1134909_101	643867.Ftrac_2895	7.436e-61	214.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47QG6@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_1134909_78	1237149.C900_02464	2.016e-90	314.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,47MAE@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
CMS2_k127_1134909_74	1279009.ADICEAN_01405	3.262e-96	323.0	COG1583@1|root,COG1583@2|Bacteria,4NJ54@976|Bacteroidetes,47MMT@768503|Cytophagia	976|Bacteroidetes	L	PFAM CRISPR associated protein Cas6	-	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
CMS2_k127_1134909_32	1237149.C900_02461	1.502e-174	552.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,47KXT@768503|Cytophagia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS2_k127_1134909_63	1121904.ARBP01000002_gene7204	1.684e-105	354.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47KKW@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS2_k127_1134909_110	1237149.C900_05084	2.904e-50	180.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,47R7K@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
CMS2_k127_1134909_46	1237149.C900_05083	6.323e-142	455.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,47JTH@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS2_k127_1134909_105	926556.Echvi_2528	9.87e-59	204.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,47Y9S@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
CMS2_k127_1134909_75	1237149.C900_05081	1.635e-93	317.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,47K6Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
CMS2_k127_1134909_137	929556.Solca_1104	2.792e-14	89.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4PIW4@976|Bacteroidetes,1IYR2@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS2_k127_1134909_16	1185876.BN8_00471	2.059e-225	783.0	COG2133@1|root,COG2373@1|root,COG3291@1|root,COG4932@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K12287,ko:K12549,ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02044	-	-	-	Big_3_2,CHU_C,DUF4347,HemolysinCabind,Laminin_G_3
CMS2_k127_1134909_1	1237149.C900_03347	0.0	1424.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS2_k127_1134909_122	1443665.JACA01000024_gene3356	3.179e-33	132.0	COG1714@1|root,COG1714@2|Bacteria,4PC58@976|Bacteroidetes,1ICKG@117743|Flavobacteriia,2YM2F@290174|Aquimarina	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1134909_125	404589.Anae109_3999	8.894e-30	136.0	COG0265@1|root,COG2114@1|root,COG4916@1|root,COG0265@2|Bacteria,COG2114@2|Bacteria,COG4916@2|Bacteria,1R86S@1224|Proteobacteria,4317C@68525|delta/epsilon subdivisions,2WWWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1134909_99	1492737.FEM08_15640	4.983e-63	230.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia,2P0RI@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,PAS_3,PAS_9
CMS2_k127_1134909_123	1121859.KB890756_gene1494	6.697e-33	134.0	COG1556@1|root,COG1556@2|Bacteria,4NQSF@976|Bacteroidetes,47QGX@768503|Cytophagia	976|Bacteroidetes	S	LUD domain	lutC	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
CMS2_k127_1134909_29	388413.ALPR1_05920	8.899e-177	564.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,47K0Z@768503|Cytophagia	976|Bacteroidetes	C	LUD domain	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
CMS2_k127_1134909_100	1121904.ARBP01000002_gene7043	9.836e-63	224.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,47KGV@768503|Cytophagia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
CMS2_k127_1134909_47	1279009.ADICEAN_00906	4.483e-141	471.0	COG1305@1|root,COG1305@2|Bacteria,4PMBI@976|Bacteroidetes,47YQ0@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
CMS2_k127_1134909_34	1279009.ADICEAN_00907	8.504e-173	564.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,47KR7@768503|Cytophagia	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
CMS2_k127_1134909_22	1279009.ADICEAN_00908	7.122e-214	703.0	COG0457@1|root,COG2849@1|root,COG0457@2|Bacteria,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47N8G@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_8
CMS2_k127_1134909_93	313606.M23134_07170	2.991e-71	258.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NN66@976|Bacteroidetes,47Q5A@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
CMS2_k127_1134909_10	1121859.KB890738_gene2927	2.151e-287	886.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1134909_12	1123248.KB893359_gene2156	7.097e-255	818.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,4NGAU@976|Bacteroidetes,1IWXQ@117747|Sphingobacteriia	976|Bacteroidetes	CG	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_1134909_53	1121904.ARBP01000068_gene5318	4.544e-127	422.0	COG4251@1|root,COG4251@2|Bacteria,4NHEM@976|Bacteroidetes,47QEB@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
CMS2_k127_1134909_103	1121904.ARBP01000007_gene2975	5.391e-60	234.0	COG4251@1|root,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,47XFE@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_1134909_11	886377.Murru_1258	4.854e-286	902.0	COG2866@1|root,COG2866@2|Bacteria,4NF3D@976|Bacteroidetes,1I8CA@117743|Flavobacteriia	976|Bacteroidetes	M	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_1134909_113	1168034.FH5T_18990	1.329e-47	175.0	COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,2FS52@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
CMS2_k127_1134909_124	313606.M23134_02861	7.011e-30	123.0	COG2885@1|root,COG2885@2|Bacteria,4P5MU@976|Bacteroidetes	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS2_k127_1134909_133	1237149.C900_02065	3.32e-16	86.0	2EJ5R@1|root,33CWY@2|Bacteria,4NYJK@976|Bacteroidetes,47SY4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1134909_94	1048983.EL17_07395	1.415e-70	243.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS2_k127_1134909_27	1237149.C900_01354	6.389e-187	603.0	COG2203@1|root,COG2203@2|Bacteria,4NICW@976|Bacteroidetes,47NI3@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_9
CMS2_k127_1134909_35	1237149.C900_01349	9.853e-172	547.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,47JS1@768503|Cytophagia	976|Bacteroidetes	S	PFAM FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
CMS2_k127_1134909_121	926549.KI421517_gene1987	2.701e-34	135.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia	976|Bacteroidetes	H	MoeZ MoeB domain	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CMS2_k127_1134909_127	1453500.AT05_01575	1.012e-28	119.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
CMS2_k127_1134909_38	1237149.C900_05159	1.672e-166	527.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,47KPU@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS2_k127_1134909_67	643867.Ftrac_3553	5.326e-103	343.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,47KBM@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
CMS2_k127_1134909_108	1237149.C900_05163	3.506e-53	202.0	COG0484@1|root,COG4783@1|root,COG0484@2|Bacteria,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K21010	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	DUF560,DnaJ,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
CMS2_k127_1134909_111	1237149.C900_00592	3.582e-50	188.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
CMS2_k127_1134909_80	1237149.C900_05312	3.081e-87	295.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS2_k127_1134909_8	1124780.ANNU01000036_gene34	1.557e-298	932.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,47M9P@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
CMS2_k127_1134909_76	1237149.C900_03606	1.606e-92	309.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,47JS7@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS2_k127_1134909_17	1237149.C900_03605	7.444e-222	692.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,47JZU@768503|Cytophagia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS2_k127_1134909_7	926549.KI421517_gene8	1.127e-316	997.0	COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,47JU2@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS2_k127_1134909_50	1237149.C900_04032	9.411e-137	454.0	COG3447@1|root,COG4251@1|root,COG3447@2|Bacteria,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1
CMS2_k127_1134909_25	1122176.KB903565_gene3327	6.357e-206	653.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,4NK7Y@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
CMS2_k127_1134909_0	1122176.KB903565_gene3328	0.0	1573.0	COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes	976|Bacteroidetes	C	Molybdopterin oxidoreductase	-	-	1.7.2.3,1.8.5.5	ko:K07812,ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.4,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS2_k127_1134909_28	870187.Thini_0272	1.804e-177	572.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales	72273|Thiotrichales	P	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CMS2_k127_1134909_102	643867.Ftrac_2134	1.793e-60	222.0	COG0457@1|root,COG0457@2|Bacteria,4NGID@976|Bacteroidetes,47PKP@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1135364_5	929713.NIASO_09420	3.671e-97	330.0	COG0705@1|root,COG0705@2|Bacteria,4NP9G@976|Bacteroidetes,1IUQ8@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
CMS2_k127_1135364_8	926556.Echvi_2794	5.707e-61	218.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
CMS2_k127_1135364_0	1048983.EL17_03055	0.0	1105.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS2_k127_1135364_4	643867.Ftrac_3251	1.823e-129	416.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CMS2_k127_1135364_6	1408473.JHXO01000004_gene258	6.518e-87	295.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,2FNHW@200643|Bacteroidia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
CMS2_k127_1135364_7	946077.W5A_01285	5.215e-61	219.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
CMS2_k127_1135364_3	926549.KI421517_gene3363	1.273e-139	453.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
CMS2_k127_1135364_9	1121896.JMLU01000004_gene2644	1.554e-21	98.0	2AIZR@1|root,319HS@2|Bacteria,4P8CX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1135364_2	1121904.ARBP01000016_gene5221	5.667e-140	456.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS2_k127_1135364_1	1121904.ARBP01000016_gene5220	7.605e-232	731.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia	976|Bacteroidetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS2_k127_1135365_29	1237149.C900_00204	2.124e-31	127.0	COG3209@1|root,COG3209@2|Bacteria,4NW4C@976|Bacteroidetes,47VZV@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1135365_27	643867.Ftrac_2275	6.64e-42	159.0	COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,47PEH@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	spr	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	LysM,NLPC_P60
CMS2_k127_1135365_1	1237149.C900_01151	0.0	1244.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
CMS2_k127_1135365_7	1237149.C900_01149	1.772e-200	642.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS2_k127_1135365_4	1250278.JQNQ01000001_gene1898	6.97e-306	965.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1I0N1@117743|Flavobacteriia	976|Bacteroidetes	GV	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CMS2_k127_1135365_13	1123248.KB893331_gene3783	2.3e-152	497.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS2_k127_1135365_5	760192.Halhy_6547	1.404e-279	871.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1IPSI@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
CMS2_k127_1135365_23	1121129.KB903370_gene94	1.602e-66	245.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,2FM5V@200643|Bacteroidia,22VZV@171551|Porphyromonadaceae	976|Bacteroidetes	M	transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS2_k127_1135365_19	1168034.FH5T_15130	1.001e-109	372.0	COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,2G37X@200643|Bacteroidia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS2_k127_1135365_17	1168034.FH5T_15135	1.503e-112	377.0	COG2755@1|root,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,2FN21@200643|Bacteroidia	976|Bacteroidetes	E	COG NOG14456 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
CMS2_k127_1135365_6	1168034.FH5T_15140	2.837e-203	646.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS2_k127_1135365_24	1048983.EL17_14525	1.213e-57	207.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,47N8U@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_1135365_10	946077.W5A_08707	4.459e-164	529.0	COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1HWZF@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
CMS2_k127_1135365_2	946077.W5A_08702	0.0	1224.0	COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1IJ5T@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1135365_26	269798.CHU_0454	1.212e-42	156.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,47R69@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS2_k127_1135365_28	1305737.JAFX01000001_gene1930	5.219e-36	138.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,47R7R@768503|Cytophagia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
CMS2_k127_1135365_8	1237149.C900_02810	3.858e-186	585.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,47MSG@768503|Cytophagia	976|Bacteroidetes	F	reductase, small chain	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS2_k127_1135365_0	1237149.C900_02809	0.0	1381.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
CMS2_k127_1135365_3	1237149.C900_03818	8.451e-315	983.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,47KEQ@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM Aspartate kinase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
CMS2_k127_1135365_20	1121904.ARBP01000006_gene3774	3.456e-99	332.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,47KGY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS2_k127_1135365_14	1121930.AQXG01000003_gene2641	3.65e-148	481.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CMS2_k127_1135365_9	929556.Solca_3620	7.225e-186	589.0	COG0304@1|root,COG0304@2|Bacteria,4NDVU@976|Bacteroidetes,1IQ5G@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS2_k127_1135365_21	1237149.C900_05249	1.398e-80	274.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
CMS2_k127_1135365_12	1237149.C900_05868	1.24e-157	502.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS2_k127_1135365_15	1121904.ARBP01000007_gene3035	1.386e-146	482.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,47KZJ@768503|Cytophagia	976|Bacteroidetes	L	PFAM PHP domain	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,HHH_8,PHP
CMS2_k127_1135365_25	1237149.C900_05866	2.339e-53	190.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,47QAF@768503|Cytophagia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS2_k127_1135365_30	1089547.KB913013_gene255	2.101e-14	86.0	28KQM@1|root,2ZA8D@2|Bacteria,4NG3K@976|Bacteroidetes,47XIW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1135365_22	1237149.C900_05853	1.487e-71	246.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,47MTK@768503|Cytophagia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS2_k127_1135365_11	1237149.C900_05852	3.943e-161	512.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,47KS2@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS2_k127_1135365_16	643867.Ftrac_3649	1.24e-132	431.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,47PB1@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_1135365_18	1237149.C900_04307	1.139e-110	373.0	28JFD@1|root,2Z99B@2|Bacteria,4NFQJ@976|Bacteroidetes,47NU1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OprD
CMS2_k127_11505_0	980584.AFPB01000150_gene505	7.568e-159	504.0	COG3677@1|root,COG3677@2|Bacteria,4NHYS@976|Bacteroidetes,1I68J@117743|Flavobacteriia	976|Bacteroidetes	L	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
CMS2_k127_1168027_5	1123276.KB893263_gene4674	2.162e-133	440.0	COG1538@1|root,COG1538@2|Bacteria,4NGXM@976|Bacteroidetes,47KVY@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_1168027_1	1288963.ADIS_1550	3.038e-189	601.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47XCU@768503|Cytophagia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_1168027_4	926556.Echvi_4617	1.106e-133	440.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia	976|Bacteroidetes	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD,HlyD_3,HlyD_D23
CMS2_k127_1168027_2	1237149.C900_05605	1.946e-169	542.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47JWH@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_1168027_3	1237149.C900_05604	8e-163	522.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia	976|Bacteroidetes	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD,HlyD_3,HlyD_D23
CMS2_k127_1168027_7	411476.BACOVA_05151	1.147e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,4NSV9@976|Bacteroidetes,2FNS8@200643|Bacteroidia,4AW9G@815|Bacteroidaceae	976|Bacteroidetes	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
CMS2_k127_1168027_6	411476.BACOVA_04150	3.095e-65	238.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,2FQ9J@200643|Bacteroidia,4AW7N@815|Bacteroidaceae	976|Bacteroidetes	PT	Sigma factor regulatory protein, FecR PupR family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4880,DUF4974,FecR
CMS2_k127_1168027_0	926549.KI421517_gene1008	3.618e-220	712.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug
CMS2_k127_1168027_8	926556.Echvi_1908	6.219e-05	47.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807,DUF4097
CMS2_k127_1170256_21	1237149.C900_04582	3.667e-16	78.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_1170256_18	1237149.C900_04583	6.726e-44	162.0	2D41J@1|root,32TG2@2|Bacteria,4NTNX@976|Bacteroidetes,47RJ7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1170256_14	1121904.ARBP01000033_gene3168	1.023e-108	363.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,47JXR@768503|Cytophagia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS2_k127_1170256_17	926549.KI421517_gene1185	5.475e-47	189.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,47NVM@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
CMS2_k127_1170256_12	1237149.C900_04588	3.872e-133	427.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,47JYP@768503|Cytophagia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS2_k127_1170256_10	1123277.KB893172_gene824	2.442e-147	472.0	COG0535@1|root,COG0535@2|Bacteria,4NJ4D@976|Bacteroidetes,47K2Y@768503|Cytophagia	976|Bacteroidetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS2_k127_1170256_2	926556.Echvi_0762	6.019e-244	757.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS2_k127_1170256_8	1237149.C900_01796	5.644e-154	496.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,47JES@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS2_k127_1170256_15	1237149.C900_01795	6.91e-68	240.0	28JI1@1|root,2Z9BG@2|Bacteria,4NMDW@976|Bacteroidetes,47Q2P@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1170256_20	1237149.C900_02851	1.839e-21	96.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,47RW5@768503|Cytophagia	976|Bacteroidetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS2_k127_1170256_16	1237149.C900_02852	2.771e-47	175.0	2E0QA@1|root,32W90@2|Bacteria,4NUC6@976|Bacteroidetes,47RSZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1170256_4	1237149.C900_02753	2.61e-210	663.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS2_k127_1170256_3	1237149.C900_02752	2.785e-213	669.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,47NY5@768503|Cytophagia	976|Bacteroidetes	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS2_k127_1170256_19	313606.M23134_00502	4.814e-32	130.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,47PP1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
CMS2_k127_1170256_9	153721.MYP_4536	4.048e-148	477.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,47M8P@768503|Cytophagia	976|Bacteroidetes	S	PFAM PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
CMS2_k127_1170256_6	1121859.KB890741_gene3696	1.819e-172	550.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,47JIA@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS2_k127_1170256_0	1237149.C900_02748	0.0	1103.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,47JD8@768503|Cytophagia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS2_k127_1170256_13	1237149.C900_02747	1.009e-129	421.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,47KGF@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS2_k127_1170256_11	1124780.ANNU01000028_gene962	1.07e-143	463.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,47KJZ@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS2_k127_1170256_7	1237149.C900_02605	3.721e-155	522.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,47MS3@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
CMS2_k127_1170256_5	1237149.C900_02606	4.893e-202	643.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,47KIC@768503|Cytophagia	976|Bacteroidetes	M	PFAM Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS2_k127_1170256_23	1230342.CTM_01624	2.61e-10	69.0	COG1776@1|root,COG1776@2|Bacteria,1V9D5@1239|Firmicutes,24GE0@186801|Clostridia,36IGE@31979|Clostridiaceae	186801|Clostridia	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
CMS2_k127_1170256_1	1286632.P278_08660	8.942e-305	945.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS2_k127_1174863_14	926562.Oweho_1239	2.873e-20	95.0	COG1629@1|root,COG1629@2|Bacteria,4NV7C@976|Bacteroidetes,1IK6Z@117743|Flavobacteriia	976|Bacteroidetes	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CMS2_k127_1174863_9	504487.JCM19302_4250	8.246e-84	284.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1I1JF@117743|Flavobacteriia	976|Bacteroidetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS2_k127_1174863_2	1392498.JQLH01000001_gene122	8.202e-151	498.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia,2PIM2@252356|Maribacter	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
CMS2_k127_1174863_16	313603.FB2170_07989	7.47e-10	64.0	2EDMN@1|root,337HG@2|Bacteria,4NWVI@976|Bacteroidetes,1I9SP@117743|Flavobacteriia	976|Bacteroidetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS2_k127_1174863_0	1239962.C943_00084	0.0	2618.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,4NF4F@976|Bacteroidetes	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS2_k127_1174863_1	1239962.C943_00085	3.776e-226	706.0	COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_7,RnfC_N,SLBB
CMS2_k127_1174863_4	1239962.C943_00086	7.608e-140	451.0	COG4658@1|root,COG4658@2|Bacteria,4NESE@976|Bacteroidetes,47XQE@768503|Cytophagia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS2_k127_1174863_11	1239962.C943_00087	2.482e-72	252.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CMS2_k127_1174863_7	1239962.C943_00088	4.054e-95	316.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_1174863_8	1239962.C943_00089	8.892e-93	307.0	COG4657@1|root,COG4657@2|Bacteria,4NGEZ@976|Bacteroidetes,47XMF@768503|Cytophagia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_1174863_5	1239962.C943_00091	2.482e-132	426.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	petH	GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02287,ko:K02641,ko:K15511	ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	iJN678.petH	CpcD,FAD_binding_6,Fer4,NAD_binding_1
CMS2_k127_1174863_3	1250005.PHEL85_1701	2.914e-141	452.0	COG2878@1|root,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes,1I99X@117743|Flavobacteriia	976|Bacteroidetes	C	Putative Fe-S cluster	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
CMS2_k127_1174863_15	153721.MYP_1231	5.757e-16	86.0	2A9A6@1|root,30YF4@2|Bacteria,4PC8F@976|Bacteroidetes,47WYN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1174863_10	1121897.AUGO01000002_gene2185	3.584e-79	291.0	2C80G@1|root,2Z7ZW@2|Bacteria,4NNAX@976|Bacteroidetes,1I0PF@117743|Flavobacteriia,2NSAP@237|Flavobacterium	976|Bacteroidetes	S	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
CMS2_k127_1174863_6	313603.FB2170_02335	1.036e-123	419.0	COG1305@1|root,COG1305@2|Bacteria,4PIKS@976|Bacteroidetes,1IFXQ@117743|Flavobacteriia,2PIVR@252356|Maribacter	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS2_k127_1174863_19	1121904.ARBP01000005_gene4486	2.533e-05	48.0	COG4700@1|root,COG4700@2|Bacteria,4NNDR@976|Bacteroidetes	976|Bacteroidetes	S	containing a divergent form of TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,PLDc_N,TPR_7,TPR_8
CMS2_k127_1174863_12	1121875.KB907559_gene534	3.177e-44	173.0	COG0657@1|root,COG0657@2|Bacteria,4NZNT@976|Bacteroidetes	976|Bacteroidetes	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS2_k127_1174863_17	1121930.AQXG01000010_gene3064	7.071e-09	57.0	COG0614@1|root,COG0614@2|Bacteria,4NQ88@976|Bacteroidetes,1IT7V@117747|Sphingobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CMS2_k127_117684_3	313595.P700755_000932	5.077e-14	73.0	COG1426@1|root,COG1426@2|Bacteria,4PM8V@976|Bacteroidetes,1I5EI@117743|Flavobacteriia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_117684_0	1185876.BN8_05762	1.044e-31	127.0	COG2026@1|root,COG2026@2|Bacteria,4NW0W@976|Bacteroidetes,47SBC@768503|Cytophagia	976|Bacteroidetes	DJ	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	RelE
CMS2_k127_117684_1	1408433.JHXV01000039_gene2182	1.108e-29	123.0	COG2801@1|root,COG2801@2|Bacteria,4NTJY@976|Bacteroidetes	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
CMS2_k127_117684_2	1380600.AUYN01000007_gene3408	5.619e-24	106.0	COG2801@1|root,COG2801@2|Bacteria,4NTJY@976|Bacteroidetes,1I37S@117743|Flavobacteriia	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
CMS2_k127_117702_1	313595.P700755_000932	5.077e-14	73.0	COG1426@1|root,COG1426@2|Bacteria,4PM8V@976|Bacteroidetes,1I5EI@117743|Flavobacteriia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_117702_0	643867.Ftrac_1969	4.509e-76	259.0	COG4185@1|root,COG4185@2|Bacteria,4NNKA@976|Bacteroidetes,47PUV@768503|Cytophagia	976|Bacteroidetes	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
CMS2_k127_117702_2	1307761.L21SP2_3313	2.633e-12	70.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
CMS2_k127_117702_3	1008457.BAEX01000088_gene2652	4.168e-10	60.0	COG1813@1|root,COG1813@2|Bacteria,4PMJE@976|Bacteroidetes,1IKJG@117743|Flavobacteriia	976|Bacteroidetes	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_118383_12	865937.Gilli_1209	6.707e-41	152.0	COG3093@1|root,COG3093@2|Bacteria,4NSBZ@976|Bacteroidetes,1I3BH@117743|Flavobacteriia,2P7JV@244698|Gillisia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CMS2_k127_118383_10	1249975.JQLP01000005_gene1519	3.806e-42	155.0	COG3549@1|root,COG3549@2|Bacteria,4NSZ2@976|Bacteroidetes,1I4AG@117743|Flavobacteriia,2P7MK@244698|Gillisia	976|Bacteroidetes	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CMS2_k127_118383_2	313628.LNTAR_06899	2.677e-201	677.0	COG2010@1|root,COG2133@1|root,COG2755@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,HEAT_2,Lipase_GDSL_2,ThuA
CMS2_k127_118383_3	1121007.AUML01000023_gene1185	1.593e-197	619.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,1HWT1@117743|Flavobacteriia	976|Bacteroidetes	P	COG0798 Arsenite efflux pump ACR3 and related	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS2_k127_118383_6	1120968.AUBX01000016_gene1525	2.879e-69	239.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,47JGT@768503|Cytophagia	976|Bacteroidetes	S	PFAM LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS2_k127_118383_8	1237149.C900_03152	3.988e-54	201.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,47NDD@768503|Cytophagia	976|Bacteroidetes	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS2_k127_118383_11	1237149.C900_03153	4.212e-41	159.0	COG3762@1|root,COG3762@2|Bacteria	2|Bacteria	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS2_k127_118383_15	865937.Gilli_0018	1.665e-18	89.0	COG1669@1|root,COG1669@2|Bacteria,4NV8X@976|Bacteroidetes,1I3DN@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS2_k127_118383_18	1280706.AUJE01000041_gene866	5.574e-09	58.0	COG1073@1|root,COG1073@2|Bacteria,1UKAH@1239|Firmicutes	1239|Firmicutes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS2_k127_118383_13	1121904.ARBP01000002_gene6796	4.736e-25	117.0	2F91A@1|root,341CZ@2|Bacteria,4P4B9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_118383_7	1317122.ATO12_24670	6.021e-59	211.0	COG2259@1|root,COG2259@2|Bacteria,4NK73@976|Bacteroidetes,1I0YP@117743|Flavobacteriia,2YJR6@290174|Aquimarina	976|Bacteroidetes	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_118383_14	1233951.IO90_09795	7.552e-19	96.0	2ABZY@1|root,33Q92@2|Bacteria,4P1Q2@976|Bacteroidetes,1I7CC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_118383_5	471854.Dfer_5409	8.29e-88	295.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,47M41@768503|Cytophagia	976|Bacteroidetes	S	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,Peptidase_S9
CMS2_k127_118383_17	1185876.BN8_02030	1.938e-10	66.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,47M41@768503|Cytophagia	976|Bacteroidetes	S	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,Peptidase_S9
CMS2_k127_118383_1	1288963.ADIS_3399	1.823e-221	694.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_118383_0	1392498.JQLH01000001_gene309	0.0	1035.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HYU9@117743|Flavobacteriia,2PIWF@252356|Maribacter	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_118383_16	865938.Weevi_0151	1.567e-10	65.0	2BJIX@1|root,32DVY@2|Bacteria,4NR83@976|Bacteroidetes,1I4HT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_118383_4	566466.NOR53_520	2.853e-93	319.0	COG2706@1|root,COG2706@2|Bacteria,1RB92@1224|Proteobacteria,1SG63@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS2_k127_118383_9	1408433.JHXV01000012_gene3953	2.967e-47	177.0	COG1434@1|root,COG1434@2|Bacteria,4NP6B@976|Bacteroidetes,1I2IA@117743|Flavobacteriia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS2_k127_1197043_0	929703.KE386491_gene3608	3.209e-220	711.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1197043_1	485917.Phep_1329	1.703e-142	465.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,1IRPH@117747|Sphingobacteriia	976|Bacteroidetes	G	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
CMS2_k127_1197043_4	1237149.C900_02514	4.962e-57	213.0	COG3489@1|root,COG3489@2|Bacteria,4NFAT@976|Bacteroidetes,47NBA@768503|Cytophagia	976|Bacteroidetes	S	Imelysin	-	-	-	ko:K07338	-	-	-	-	ko00000	-	-	-	Peptidase_M75
CMS2_k127_1197043_3	643867.Ftrac_2418	3.187e-70	252.0	28HNS@1|root,2Z7WY@2|Bacteria,4NDYC@976|Bacteroidetes,47RCV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4856)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4856
CMS2_k127_1197043_2	760192.Halhy_6252	5.914e-96	327.0	COG4299@1|root,COG4299@2|Bacteria,4NIQV@976|Bacteroidetes,1IR87@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CMS2_k127_1201993_0	1121904.ARBP01000005_gene4768	9.049e-194	609.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,47JDD@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1201993_3	1237149.C900_04066	7.268e-71	249.0	COG1216@1|root,COG1216@2|Bacteria,4NJQR@976|Bacteroidetes,47MWK@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_1201993_6	643867.Ftrac_0083	2.249e-18	98.0	COG2244@1|root,COG2244@2|Bacteria,4P9TC@976|Bacteroidetes,47S12@768503|Cytophagia	976|Bacteroidetes	S	polysaccharide biosynthetic process	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	-
CMS2_k127_1201993_5	313606.M23134_04601	5.243e-26	119.0	COG5653@1|root,COG5653@2|Bacteria,4NKJS@976|Bacteroidetes,47NWT@768503|Cytophagia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
CMS2_k127_1201993_7	84531.JMTZ01000128_gene391	0.0004367	49.0	COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,1S9FD@1236|Gammaproteobacteria,1X6EP@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
CMS2_k127_1201993_4	643867.Ftrac_0011	4.548e-60	211.0	COG2050@1|root,COG2050@2|Bacteria,4P2ZC@976|Bacteroidetes	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
CMS2_k127_1201993_1	398720.MED217_13334	7.989e-85	287.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1HYT7@117743|Flavobacteriia,2XJ9M@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_1201993_2	487796.Flav2ADRAFT_1625	5.219e-82	273.0	COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes,1HXAS@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
CMS2_k127_1208274_0	1237149.C900_02559	3.178e-211	665.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,47JY4@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
CMS2_k127_1208274_2	700598.Niako_0720	1.854e-199	632.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,1IP31@117747|Sphingobacteriia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS2_k127_1208274_1	487796.Flav2ADRAFT_1622	4.27e-202	642.0	COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,1HZVQ@117743|Flavobacteriia	976|Bacteroidetes	C	Oxidoreductase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS2_k127_1208274_3	616991.JPOO01000001_gene4413	1.968e-66	233.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1HY94@117743|Flavobacteriia,23FRQ@178469|Arenibacter	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS2_k127_1238615_5	1202532.FF52_08374	2.303e-17	86.0	COG2827@1|root,COG2827@2|Bacteria,4NUW1@976|Bacteroidetes,1I5HH@117743|Flavobacteriia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS2_k127_1238615_0	926549.KI421517_gene671	1.422e-101	336.0	COG2801@1|root,COG2801@2|Bacteria,4NIBY@976|Bacteroidetes,47PAT@768503|Cytophagia	976|Bacteroidetes	L	Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
CMS2_k127_1238615_3	927658.AJUM01000045_gene2	4.052e-38	144.0	COG2963@1|root,COG2963@2|Bacteria,4NSUA@976|Bacteroidetes,2G29G@200643|Bacteroidia,3XKFP@558415|Marinilabiliaceae	976|Bacteroidetes	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
CMS2_k127_1238615_1	760192.Halhy_5684	2.782e-87	291.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1ISDK@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_1238615_2	378806.STAUR_3895	4.071e-54	199.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1R85W@1224|Proteobacteria	1224|Proteobacteria	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
CMS2_k127_1238615_4	1120965.AUBV01000006_gene2235	3.694e-33	132.0	COG2957@1|root,COG2957@2|Bacteria,4NRPH@976|Bacteroidetes,47QUY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CMS2_k127_1241640_0	714943.Mucpa_1386	9.486e-85	306.0	COG0265@1|root,COG1404@1|root,COG0265@2|Bacteria,COG1404@2|Bacteria,4PKT1@976|Bacteroidetes,1IW78@117747|Sphingobacteriia	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2,fn3
CMS2_k127_1244804_12	926556.Echvi_1575	7.977e-28	115.0	COG1943@1|root,COG1943@2|Bacteria,4NJZI@976|Bacteroidetes,47PW0@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_1244804_1	1121904.ARBP01000007_gene3017	5.394e-288	893.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS2_k127_1244804_11	1237149.C900_00723	2.872e-35	142.0	2E7DW@1|root,331WY@2|Bacteria,4NUZQ@976|Bacteroidetes,47RNZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1244804_10	643867.Ftrac_2980	6.181e-58	205.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,47PPY@768503|Cytophagia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
CMS2_k127_1244804_8	381666.H16_A2216	3.235e-73	256.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2VTNF@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
CMS2_k127_1244804_3	504487.JCM19302_3744	1.279e-227	715.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1HZQ7@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS2_k127_1244804_7	865937.Gilli_2297	8.839e-105	353.0	29CKG@1|root,2ZZIT@2|Bacteria,4PFME@976|Bacteroidetes,1I7JJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1244804_4	1416760.AYMS01000025_gene2779	1.376e-156	503.0	COG4260@1|root,COG4260@2|Bacteria,4NHXG@976|Bacteroidetes,1I0MU@117743|Flavobacteriia	976|Bacteroidetes	S	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR
CMS2_k127_1244804_6	880071.Fleli_2454	1.303e-114	380.0	COG1996@1|root,COG1996@2|Bacteria,4NFZ3@976|Bacteroidetes	976|Bacteroidetes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1244804_5	388413.ALPR1_18068	7.604e-125	407.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47MIQ@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1244804_2	1237149.C900_02195	1.994e-241	754.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS2_k127_1244804_13	643867.Ftrac_1197	1.451e-23	108.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS2_k127_1244804_0	761193.Runsl_3094	0.0	1299.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS2_k127_1244804_14	1333507.AUTQ01000207_gene1531	9.884e-18	83.0	2CJ4Q@1|root,32S97@2|Bacteria,1N0B9@1224|Proteobacteria,1S97T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ethyl tert-butyl ether degradation	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
CMS2_k127_1244804_9	36875.HQ29_07965	3.135e-60	216.0	COG0666@1|root,COG1372@1|root,COG0666@2|Bacteria,COG1372@2|Bacteria,4NK85@976|Bacteroidetes,2FQQ2@200643|Bacteroidia,22Z1K@171551|Porphyromonadaceae	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	AXH,NADase_NGA
CMS2_k127_1247846_15	1121904.ARBP01000019_gene2784	4.447e-157	503.0	COG3525@1|root,COG3525@2|Bacteria,4NGV2@976|Bacteroidetes,47TJT@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20
CMS2_k127_1247846_43	485915.Dret_0948	4.526e-08	54.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria,2MGFG@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM multicopper oxidase type	cumA	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS2_k127_1247846_18	867902.Ornrh_1375	3.1e-137	447.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_1247846_9	1121904.ARBP01000085_gene3653	1.36e-177	572.0	COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,47NF5@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_1247846_25	1123248.KB893321_gene459	8.873e-87	294.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,1IRCI@117747|Sphingobacteriia	976|Bacteroidetes	G	Trehalose utilisation	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
CMS2_k127_1247846_6	1120966.AUBU01000017_gene703	2.95e-220	693.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KU8@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CMS2_k127_1247846_5	1237149.C900_00061	3.44e-236	757.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,47MWS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
CMS2_k127_1247846_32	1034807.FBFL15_1814	6.917e-63	220.0	COG1943@1|root,COG1943@2|Bacteria,4NR8E@976|Bacteroidetes,1IJ2F@117743|Flavobacteriia,2P0ID@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_1247846_1	1313301.AUGC01000012_gene1384	0.0	1191.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS2_k127_1247846_4	706587.Desti_0641	1.431e-241	765.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2MQ64@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CMS2_k127_1247846_23	491205.JARQ01000007_gene2991	1.177e-111	365.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,3ZPXV@59732|Chryseobacterium	976|Bacteroidetes	T	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS2_k127_1247846_34	573061.Clocel_2544	1.631e-52	196.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia,36F2I@31979|Clostridiaceae	186801|Clostridia	NT	Methyltransferase	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS2_k127_1247846_38	1124780.ANNU01000048_gene2151	5.109e-40	157.0	COG0565@1|root,COG0565@2|Bacteria	2|Bacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS2_k127_1247846_35	1408813.AYMG01000028_gene2442	1.024e-47	178.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1ITNU@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_1247846_31	697303.Thewi_1548	9.551e-66	238.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,42EMH@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
CMS2_k127_1247846_36	1168034.FH5T_11820	2.747e-46	171.0	COG0454@1|root,COG0456@2|Bacteria,4NT3M@976|Bacteroidetes,2FYWS@200643|Bacteroidia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_1247846_20	643867.Ftrac_1925	1.834e-127	416.0	COG1226@1|root,COG1226@2|Bacteria,4NMSS@976|Bacteroidetes,47UA5@768503|Cytophagia	976|Bacteroidetes	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
CMS2_k127_1247846_40	929713.NIASO_06430	1.147e-36	142.0	COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional repressor, CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS2_k127_1247846_37	1121904.ARBP01000009_gene4328	7.832e-41	171.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS2_k127_1247846_39	1121875.KB907549_gene2104	2.82e-38	147.0	COG3059@1|root,COG3059@2|Bacteria,4NNX8@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
CMS2_k127_1247846_11	742766.HMPREF9455_03572	1.76e-175	561.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia,22X3X@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS2_k127_1247846_7	1237149.C900_05890	2.034e-184	610.0	COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes,47MS8@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_1247846_17	1237149.C900_03983	1.455e-140	462.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS2_k127_1247846_30	1237149.C900_02771	1.471e-69	240.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,47PV2@768503|Cytophagia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
CMS2_k127_1247846_13	216432.CA2559_11013	4.94e-172	551.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS2_k127_1247846_14	1239962.C943_00719	9.168e-170	539.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS2_k127_1247846_10	1237149.C900_02768	1.38e-177	568.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS2_k127_1247846_42	1356852.N008_12035	1.004e-15	79.0	2A7GX@1|root,30WEH@2|Bacteria,4P9UT@976|Bacteroidetes,47S3Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1247846_16	1237149.C900_04413	3.768e-153	494.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,47K5F@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS2_k127_1247846_8	1237149.C900_04416	3.322e-182	579.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,47KB8@768503|Cytophagia	976|Bacteroidetes	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_1247846_29	1237149.C900_04417	2.728e-78	283.0	COG0683@1|root,COG0683@2|Bacteria,4PKN8@976|Bacteroidetes,47NJW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS2_k127_1247846_2	926549.KI421517_gene3894	3.791e-255	794.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS2_k127_1247846_0	643867.Ftrac_0827	0.0	1674.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS2_k127_1247846_22	643867.Ftrac_3594	3.545e-115	383.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,47MFH@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CMS2_k127_1247846_3	1237149.C900_04407	1.36e-249	790.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS2_k127_1247846_27	926556.Echvi_2921	1.082e-83	285.0	COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,47KFU@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_1247846_21	1237149.C900_02767	4.799e-126	409.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,47JAQ@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS2_k127_1247846_12	1237149.C900_02766	2.812e-174	551.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,47M82@768503|Cytophagia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS2_k127_1247846_24	1237149.C900_02765	1.356e-103	347.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,47N34@768503|Cytophagia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS2_k127_1247846_33	1237149.C900_02763	1.186e-61	220.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,47Q1F@768503|Cytophagia	976|Bacteroidetes	P	ZIP Zinc transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
CMS2_k127_1247846_28	1237149.C900_01486	3.929e-83	282.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_1247846_41	1124780.ANNU01000064_gene450	7.876e-19	103.0	COG3291@1|root,COG3291@2|Bacteria,4PHTU@976|Bacteroidetes,47P4N@768503|Cytophagia	976|Bacteroidetes	E	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_1247846_19	313606.M23134_02237	1.441e-136	475.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_125056_1	1249997.JHZW01000002_gene1571	2.748e-24	103.0	COG3344@1|root,COG3344@2|Bacteria,4NHMS@976|Bacteroidetes,1HZPH@117743|Flavobacteriia	976|Bacteroidetes	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
CMS2_k127_125056_2	1288963.ADIS_4707	7.201e-16	79.0	COG3344@1|root,COG3344@2|Bacteria,4NHMS@976|Bacteroidetes,47MYV@768503|Cytophagia	976|Bacteroidetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
CMS2_k127_125056_0	1122621.ATZA01000016_gene3811	6.016e-228	730.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ0T@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_125056_3	1538644.KO02_05270	4.526e-08	54.0	COG1484@1|root,COG1484@2|Bacteria,4NM7S@976|Bacteroidetes,1IVS8@117747|Sphingobacteriia	976|Bacteroidetes	O	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
CMS2_k127_1265853_4	1121904.ARBP01000032_gene2025	1.043e-205	647.0	COG0436@1|root,COG0436@2|Bacteria,4NFUY@976|Bacteroidetes,47MC8@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS2_k127_1265853_13	388413.ALPR1_02755	2.219e-145	470.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,47MAZ@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS2_k127_1265853_5	485917.Phep_1412	1.329e-191	607.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS2_k127_1265853_11	1120965.AUBV01000005_gene1543	5.059e-148	474.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,47K34@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS2_k127_1265853_15	1408473.JHXO01000012_gene442	7.11e-105	349.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,2FQ6R@200643|Bacteroidia	976|Bacteroidetes	S	esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS2_k127_1265853_3	1249975.JQLP01000001_gene3078	1.148e-207	662.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia,2P7H9@244698|Gillisia	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CMS2_k127_1265853_23	5911.EAR82986	2.873e-18	89.0	COG0450@1|root,KOG0852@2759|Eukaryota,3ZDU1@5878|Ciliophora	5878|Ciliophora	E	Protozoan cyanobacterial globin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin
CMS2_k127_1265853_19	1237149.C900_01767	8.848e-76	258.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CMS2_k127_1265853_1	1237149.C900_03138	3.722e-253	787.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,47KQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS2_k127_1265853_0	1237149.C900_03128	2.699e-257	810.0	COG2208@1|root,COG2208@2|Bacteria,4NJMJ@976|Bacteroidetes,47JNJ@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
CMS2_k127_1265853_21	1237149.C900_03127	1.253e-31	127.0	COG1366@1|root,COG1366@2|Bacteria,4NVHQ@976|Bacteroidetes,47RVX@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS2_k127_1265853_20	1121904.ARBP01000012_gene1187	1.133e-35	139.0	COG2172@1|root,COG2172@2|Bacteria,4NV3J@976|Bacteroidetes,47RU2@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS2_k127_1265853_7	1237149.C900_03125	2.669e-166	543.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
CMS2_k127_1265853_14	1237149.C900_03124	2.107e-114	377.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,47NE3@768503|Cytophagia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
CMS2_k127_1265853_12	1237149.C900_03123	5.511e-146	475.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,47JPW@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
CMS2_k127_1265853_8	1237149.C900_03122	8.814e-166	525.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KTK@768503|Cytophagia	976|Bacteroidetes	S	PFAM ATPase associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS2_k127_1265853_22	1356852.N008_09850	5.419e-24	107.0	COG2146@1|root,COG2146@2|Bacteria,4NV1B@976|Bacteroidetes,47S5J@768503|Cytophagia	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1265853_16	643867.Ftrac_2391	2.802e-100	334.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,47XHJ@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS2_k127_1265853_9	1123057.P872_06955	1.724e-164	523.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS2_k127_1265853_2	1237149.C900_03118	1.638e-229	715.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
CMS2_k127_1265853_10	1237149.C900_03116	6.227e-164	518.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,47JCC@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS2_k127_1265853_18	1237149.C900_03115	7.981e-90	299.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,47NAS@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS2_k127_1265853_17	1237149.C900_03114	7.287e-97	322.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,47PAU@768503|Cytophagia	976|Bacteroidetes	P	Inositol monophosphatase family	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS2_k127_1265853_6	1250232.JQNJ01000001_gene1947	6.421e-171	543.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1HX1B@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CMS2_k127_1283826_1	1237149.C900_04421	2.261e-143	468.0	COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia	976|Bacteroidetes	C	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
CMS2_k127_1283826_0	1237149.C900_04422	1.1e-156	507.0	28KMN@1|root,2ZA61@2|Bacteria,4NJ9P@976|Bacteroidetes,47P0N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062
CMS2_k127_1289596_14	1249997.JHZW01000003_gene3005	1.975e-12	67.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1HZ97@117743|Flavobacteriia,2PH89@252356|Maribacter	976|Bacteroidetes	E	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS2_k127_1289596_5	980584.AFPB01000007_gene1095	2.592e-89	299.0	COG4804@1|root,COG4804@2|Bacteria,4NE0Q@976|Bacteroidetes,1I0HU@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
CMS2_k127_1289596_0	1049564.TevJSym_bb00050	5.767e-242	763.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS2_k127_1289596_2	1049564.TevJSym_bb00040	4.228e-104	347.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS2_k127_1289596_8	1049564.TevJSym_bb00030	2.386e-57	226.0	COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CMS2_k127_1289596_4	382464.ABSI01000002_gene4375	1.021e-91	309.0	COG2878@1|root,COG2878@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_7
CMS2_k127_1289596_10	382464.ABSI01000002_gene4374	5.492e-35	156.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS2_k127_1289596_1	1049564.TevJSym_aq00710	2.648e-134	441.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
CMS2_k127_1289596_3	1049564.TevJSym_aq00700	7.5e-98	329.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS2_k127_1289596_9	1049564.TevJSym_aq00690	1.5e-49	184.0	COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
CMS2_k127_1289596_7	1049564.TevJSym_aq00680	2.913e-80	273.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfE2	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_1289596_6	1049564.TevJSym_aq00670	8.445e-84	283.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_1289596_11	1122176.KB903554_gene3837	4.695e-29	125.0	COG1404@1|root,COG1404@2|Bacteria,4NJHT@976|Bacteroidetes,1IUZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS2_k127_1289596_12	1168289.AJKI01000003_gene2747	1.143e-23	105.0	2DNXM@1|root,32ZP0@2|Bacteria,4NWRE@976|Bacteroidetes,2FZ1I@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1289596_16	1202532.FF52_13771	2.557e-08	59.0	COG3668@1|root,COG3668@2|Bacteria,4NXUR@976|Bacteroidetes,1II9D@117743|Flavobacteriia,2P0BT@237|Flavobacterium	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CMS2_k127_1289596_15	448385.sce9092	6.28e-11	68.0	COG4319@1|root,COG4319@2|Bacteria,1N1WC@1224|Proteobacteria	1224|Proteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_1289596_13	1237149.C900_04304	5.283e-16	78.0	COG1396@1|root,COG1396@2|Bacteria,4NR5F@976|Bacteroidetes,47VXZ@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_1290670_9	1237149.C900_04039	1.318e-39	151.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NWV@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_1290670_0	1122179.KB890419_gene24	0.0	1164.0	COG4447@1|root,COG4447@2|Bacteria,4NI14@976|Bacteroidetes	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_1290670_13	572265.HDEF_0755	5.609e-08	66.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,283BC@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS2_k127_1290670_3	1168034.FH5T_20710	5.974e-172	550.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_1290670_11	1123277.KB893184_gene4037	2.652e-32	132.0	2C45J@1|root,332RE@2|Bacteria,4NWCK@976|Bacteroidetes,47S73@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1290670_5	926549.KI421517_gene1516	8.484e-115	379.0	COG1647@1|root,COG1647@2|Bacteria,4NJCA@976|Bacteroidetes,47NWK@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS2_k127_1290670_12	1123035.ARLA01000023_gene980	9.571e-19	94.0	28KUE@1|root,2ZAB8@2|Bacteria,4PMSF@976|Bacteroidetes,1IJYN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1290670_7	1239962.C943_03769	1.66e-88	304.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_1290670_6	1249997.JHZW01000002_gene1713	2.245e-101	335.0	28HGK@1|root,2Z7SE@2|Bacteria,4NGDR@976|Bacteroidetes,1I856@117743|Flavobacteriia	976|Bacteroidetes	S	Malonate/sodium symporter MadM subunit	-	-	-	-	-	-	-	-	-	-	-	-	MadM
CMS2_k127_1290670_10	313596.RB2501_09085	1.506e-36	141.0	2CAQ0@1|root,32RRS@2|Bacteria,4NRRH@976|Bacteroidetes,1I9QS@117743|Flavobacteriia	976|Bacteroidetes	S	Malonate transporter MadL subunit	-	-	-	-	-	-	-	-	-	-	-	-	MadL
CMS2_k127_1290670_1	1249997.JHZW01000002_gene1715	6.707e-207	653.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1HZVU@117743|Flavobacteriia	976|Bacteroidetes	IQ	amp-binding	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
CMS2_k127_1290670_2	1121904.ARBP01000006_gene3720	6.074e-190	605.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47MZ0@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
CMS2_k127_1290670_8	641524.ADICYQ_3167	5.683e-63	218.0	COG2133@1|root,COG2133@2|Bacteria,4PNNH@976|Bacteroidetes,47KNR@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_1308242_9	388413.ALPR1_07475	4.266e-05	50.0	COG3437@1|root,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,47Q84@768503|Cytophagia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
CMS2_k127_1308242_7	517418.Ctha_0020	5.115e-30	123.0	COG0745@1|root,COG0745@2|Bacteria	517418.Ctha_0020|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1308242_2	1086011.HJ01_02684	5.698e-97	336.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,4NDUQ@976|Bacteroidetes,1HZ8B@117743|Flavobacteriia,2NVT8@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
CMS2_k127_1308242_5	1123277.KB893201_gene6435	7.253e-38	144.0	COG0577@1|root,COG0577@2|Bacteria,4NI0C@976|Bacteroidetes,47M9R@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_1308242_4	1121904.ARBP01000006_gene4049	1.357e-64	232.0	COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,47PWT@768503|Cytophagia	976|Bacteroidetes	E	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
CMS2_k127_1308242_0	313606.M23134_05167	2.64e-253	796.0	COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,47N77@768503|Cytophagia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
CMS2_k127_1308242_3	313603.FB2170_08949	6.083e-84	287.0	COG3439@1|root,COG3439@2|Bacteria,4NH52@976|Bacteroidetes,1I16N@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1308242_1	1121904.ARBP01000003_gene6153	1.656e-103	344.0	COG0667@1|root,COG0667@2|Bacteria,4NHAU@976|Bacteroidetes,47NRK@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_132935_0	1121875.KB907546_gene2710	0.0	1371.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,1HZ5J@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
CMS2_k127_132935_9	467661.RKLH11_3573	3.725e-121	402.0	COG5441@1|root,COG5441@2|Bacteria,1MX45@1224|Proteobacteria,2TUHA@28211|Alphaproteobacteria,3ZGA3@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,UPF0261
CMS2_k127_132935_8	314256.OG2516_16479	3.135e-122	397.0	COG5564@1|root,COG5564@2|Bacteria,1MXTY@1224|Proteobacteria,2TSJ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	TIM-barrel enzyme, possibly a dioxygenase	MA20_13935	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
CMS2_k127_132935_1	929703.KE386491_gene1729	2.436e-252	801.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_132935_2	929558.SMGD1_0536	6.693e-251	789.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2YTC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
CMS2_k127_132935_14	1089547.KB913013_gene3537	3.333e-24	103.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,47Q23@768503|Cytophagia	976|Bacteroidetes	L	transposase IS200-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_132935_13	886293.Sinac_2235	1.221e-47	180.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS2_k127_132935_3	929703.KE386491_gene4218	8.65e-197	622.0	COG1524@1|root,COG1524@2|Bacteria,4NGHN@976|Bacteroidetes,47JGA@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS2_k127_132935_7	1123057.P872_23620	4.443e-133	435.0	COG1082@1|root,COG1082@2|Bacteria,4NHXX@976|Bacteroidetes,47MGH@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_132935_6	504472.Slin_0084	2.668e-139	452.0	COG0337@1|root,COG0337@2|Bacteria,4NHE3@976|Bacteroidetes,47K3I@768503|Cytophagia	976|Bacteroidetes	E	3-dehydroquinate synthase	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS2_k127_132935_11	1453505.JASY01000017_gene4601	1.703e-75	263.0	COG0382@1|root,COG0382@2|Bacteria,4NIXM@976|Bacteroidetes,1HZ5B@117743|Flavobacteriia,2NYJS@237|Flavobacterium	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_132935_5	620914.JH621261_gene969	5.657e-157	498.0	COG1099@1|root,COG1099@2|Bacteria,4NHVD@976|Bacteroidetes,1I09X@117743|Flavobacteriia	976|Bacteroidetes	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
CMS2_k127_132935_12	1453505.JASY01000017_gene4599	1.017e-58	214.0	28JEH@1|root,2Z98N@2|Bacteria,4NJHC@976|Bacteroidetes,1I15N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_132935_15	1216967.L100_00610	9.591e-20	96.0	COG0457@1|root,COG0457@2|Bacteria,4NRXW@976|Bacteroidetes,1I2MJ@117743|Flavobacteriia,34RFG@308865|Elizabethkingia	976|Bacteroidetes	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS2_k127_132935_4	530564.Psta_0688	2.491e-165	532.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_132935_10	1185876.BN8_00013	4.72e-115	380.0	COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes,47NZQ@768503|Cytophagia	976|Bacteroidetes	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
CMS2_k127_1351714_20	1123276.KB893312_gene3009	3.661e-34	132.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,47MSJ@768503|Cytophagia	976|Bacteroidetes	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
CMS2_k127_1351714_12	929556.Solca_2525	7.586e-79	273.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1IPGU@117747|Sphingobacteriia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_1351714_3	1249997.JHZW01000003_gene3662	1.196e-175	564.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1HYG1@117743|Flavobacteriia,2PGAR@252356|Maribacter	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_1351714_5	1121904.ARBP01000013_gene317	4.217e-153	489.0	COG0388@1|root,COG0388@2|Bacteria,4NGWX@976|Bacteroidetes,47JH4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS2_k127_1351714_9	1313421.JHBV01000021_gene4855	3.805e-95	342.0	COG1629@1|root,COG4771@2|Bacteria,4NJAM@976|Bacteroidetes,1IYZQ@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS2_k127_1351714_11	313606.M23134_03841	1.303e-79	297.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47NIF@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
CMS2_k127_1351714_1	929556.Solca_2488	3.689e-289	910.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQMB@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CMS2_k127_1351714_24	1121875.KB907546_gene2760	6.164e-14	81.0	2C3TU@1|root,2ZBKB@2|Bacteria,4NMMF@976|Bacteroidetes,1I1HI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1351714_4	1500894.JQNN01000001_gene1467	3.208e-158	516.0	COG3291@1|root,COG3291@2|Bacteria,1QWZ9@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
CMS2_k127_1351714_7	313603.FB2170_15718	1.309e-116	387.0	COG0642@1|root,COG2205@2|Bacteria,4NG6V@976|Bacteroidetes,1HWTT@117743|Flavobacteriia,2PGGW@252356|Maribacter	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Response_reg
CMS2_k127_1351714_23	880070.Cycma_4894	1.811e-14	75.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
CMS2_k127_1351714_21	1392488.JHZY01000002_gene895	3.515e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia,2XKC5@283735|Leeuwenhoekiella	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_1351714_0	1237149.C900_00062	0.0	1229.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
CMS2_k127_1351714_2	1122176.KB903543_gene651	8.333e-260	810.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IPA2@117747|Sphingobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CMS2_k127_1351714_22	1189612.A33Q_2600	7.021e-20	96.0	28KSE@1|root,2ZBRS@2|Bacteria,4NNCR@976|Bacteroidetes,47P8I@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_1351714_14	1382359.JIAL01000001_gene2776	3.7e-65	229.0	COG3467@1|root,COG3467@2|Bacteria,3Y4HI@57723|Acidobacteria,2JMS6@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS2_k127_1351714_8	553177.CAPSP0001_2484	9.088e-104	345.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia,1EQRK@1016|Capnocytophaga	976|Bacteroidetes	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
CMS2_k127_1351714_19	1189612.A33Q_1700	1.226e-36	144.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
CMS2_k127_1351714_25	509635.N824_21805	1.227e-10	71.0	COG3595@1|root,COG3595@2|Bacteria,4NR7Q@976|Bacteroidetes,1ISXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_1351714_16	688270.Celal_3009	2.547e-43	163.0	COG0666@1|root,COG0666@2|Bacteria,4NSX8@976|Bacteroidetes,1I2UW@117743|Flavobacteriia,1FAD2@104264|Cellulophaga	976|Bacteroidetes	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
CMS2_k127_1351714_13	1122176.KB903545_gene885	1.937e-70	249.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1INST@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS2_k127_1351714_6	1237149.C900_00593	1.015e-147	477.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,47JJU@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_1351714_15	1279009.ADICEAN_00226	1.073e-48	178.0	29AZZ@1|root,2ZXYX@2|Bacteria,4PJYK@976|Bacteroidetes,47R16@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1351714_18	1227739.Hsw_1386	4.094e-41	161.0	COG1396@1|root,COG1396@2|Bacteria,4NHP0@976|Bacteroidetes,47UX6@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
CMS2_k127_1351714_17	980584.AFPB01000022_gene1043	5.619e-42	157.0	291R8@1|root,2ZPB9@2|Bacteria,4NPWY@976|Bacteroidetes,1I1XQ@117743|Flavobacteriia,4073G@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CesT,YbjN
CMS2_k127_1351714_10	1279009.ADICEAN_02812	8.382e-80	272.0	COG1842@1|root,COG1842@2|Bacteria,4NFSJ@976|Bacteroidetes,47PG9@768503|Cytophagia	976|Bacteroidetes	KT	Phage shock protein A (IM30) suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS2_k127_1377534_30	931276.Cspa_c03590	1.353e-50	190.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36KBS@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg,dCache_3,sCache_3_3
CMS2_k127_1377534_15	497965.Cyan7822_5299	1.485e-101	374.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3KH9M@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg,dCache_1
CMS2_k127_1377534_39	586416.GZ22_04665	2.795e-21	100.0	COG3575@1|root,COG3575@2|Bacteria,1V1YD@1239|Firmicutes,4HGK6@91061|Bacilli	91061|Bacilli	J	protein conserved in bacteria	-	-	-	ko:K09962	-	-	-	-	ko00000	-	-	-	NTP_transf_6
CMS2_k127_1377534_10	1124780.ANNU01000035_gene277	6.056e-132	424.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,47MF7@768503|Cytophagia	976|Bacteroidetes	IQ	TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_1377534_5	1121904.ARBP01000004_gene1065	9.792e-197	624.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS2_k127_1377534_36	1237149.C900_00993	1.75e-32	128.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the ClpS family	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS2_k127_1377534_21	1121481.AUAS01000001_gene4620	1.719e-81	276.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,47JZK@768503|Cytophagia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS2_k127_1377534_22	1122947.FR7_1058	5.76e-78	268.0	COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4H7AN@909932|Negativicutes	909932|Negativicutes	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CMS2_k127_1377534_26	1237149.C900_01862	6.152e-62	221.0	COG1309@1|root,COG2852@1|root,COG1309@2|Bacteria,COG2852@2|Bacteria,4NUSE@976|Bacteroidetes,47RNW@768503|Cytophagia	976|Bacteroidetes	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
CMS2_k127_1377534_28	1237149.C900_01864	6.204e-51	191.0	COG1073@1|root,COG1073@2|Bacteria,4NGDK@976|Bacteroidetes,47Q3Y@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
CMS2_k127_1377534_13	471854.Dfer_3760	3.726e-121	392.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47KDU@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_1377534_27	1123277.KB893173_gene1470	4.025e-56	201.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,47P8Y@768503|Cytophagia	976|Bacteroidetes	S	PFAM Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS2_k127_1377534_24	1237149.C900_01850	8.96e-75	267.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS2_k127_1377534_4	1237149.C900_04009	1.671e-252	782.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,47KGI@768503|Cytophagia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS2_k127_1377534_41	1121286.AUMT01000005_gene3051	7.782e-16	83.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,1I55E@117743|Flavobacteriia,3ZRZ9@59732|Chryseobacterium	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
CMS2_k127_1377534_40	1048983.EL17_13890	4.29e-19	98.0	2EDB5@1|root,3377G@2|Bacteria,4NZFE@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
CMS2_k127_1377534_2	1189612.A33Q_3940	5.571e-281	884.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47MDX@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1377534_16	1120968.AUBX01000011_gene3325	2.129e-101	336.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS2_k127_1377534_12	1089547.KB913013_gene1717	9.551e-122	398.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,47K7F@768503|Cytophagia	976|Bacteroidetes	G	Phosphomannose isomerase type I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS2_k127_1377534_38	313606.M23134_07546	1.787e-27	115.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,47QW9@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS2_k127_1377534_20	1237149.C900_02777	9.509e-85	291.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_1377534_33	313606.M23134_06350	4.657e-39	162.0	COG0642@1|root,COG2205@2|Bacteria,4NQ7H@976|Bacteroidetes,47QVS@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA
CMS2_k127_1377534_18	153721.MYP_4282	2.341e-91	306.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,47K0Q@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
CMS2_k127_1377534_31	1121859.KB890739_gene2407	4.978e-48	186.0	COG0797@1|root,COG1388@1|root,COG0797@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,47NR5@768503|Cytophagia	976|Bacteroidetes	M	PFAM LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
CMS2_k127_1377534_7	1237149.C900_02212	1.458e-174	557.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,47MQR@768503|Cytophagia	976|Bacteroidetes	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,Peptidase_S49,SDH_sah
CMS2_k127_1377534_23	679190.HMPREF0650_1503	2.348e-76	263.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,2FMHD@200643|Bacteroidia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS2_k127_1377534_11	1237149.C900_01000	1.111e-125	414.0	COG0308@1|root,COG0308@2|Bacteria,4PNPR@976|Bacteroidetes,47YF9@768503|Cytophagia	976|Bacteroidetes	E	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_1377534_17	269798.CHU_0783	4e-100	335.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,47K45@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
CMS2_k127_1377534_6	1237149.C900_00995	5.44e-181	575.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,47JJH@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_1377534_43	1121890.AUDO01000007_gene2479	4.419e-09	62.0	2CFVU@1|root,3373K@2|Bacteria,4NY6U@976|Bacteroidetes,1ID3F@117743|Flavobacteriia,2NX5E@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1377534_3	760192.Halhy_4150	7.509e-270	858.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,1IR4H@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS2_k127_1377534_37	1242864.D187_010254	2.039e-32	138.0	COG3358@1|root,COG3358@2|Bacteria,1RBIA@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CMS2_k127_1377534_14	865937.Gilli_2593	5.553e-105	347.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1HXF5@117743|Flavobacteriia,2P7D6@244698|Gillisia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
CMS2_k127_1377534_19	1317122.ATO12_04675	5.94e-86	289.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1HYYD@117743|Flavobacteriia,2YIUI@290174|Aquimarina	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
CMS2_k127_1377534_9	1137281.D778_01416	4.696e-146	474.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia	976|Bacteroidetes	P	COG3420 Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
CMS2_k127_1377534_34	746697.Aeqsu_0141	4.367e-35	138.0	COG4314@1|root,COG4314@2|Bacteria,4NVVP@976|Bacteroidetes,1I2Z0@117743|Flavobacteriia	976|Bacteroidetes	C	NosL	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS2_k127_1377534_25	1317122.ATO12_04690	7.992e-66	229.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1HXI6@117743|Flavobacteriia,2YITX@290174|Aquimarina	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS2_k127_1377534_1	1443665.JACA01000047_gene5266	0.0	1126.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,2YHS1@290174|Aquimarina	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS2_k127_1377534_29	865937.Gilli_2587	8.6e-51	186.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia,2P7JS@244698|Gillisia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS2_k127_1377534_32	1237149.C900_03373	5.043e-44	165.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes	976|Bacteroidetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_1377534_35	1317122.ATO12_04775	1.015e-32	131.0	COG1959@1|root,COG1959@2|Bacteria,4NPHI@976|Bacteroidetes,1I2QC@117743|Flavobacteriia,2YI3T@290174|Aquimarina	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS2_k127_1377534_8	468059.AUHA01000004_gene2247	2.65e-163	527.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,1IPYV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
CMS2_k127_1377534_0	566466.NOR53_1826	0.0	1469.0	COG4447@1|root,COG4447@2|Bacteria,1QYUM@1224|Proteobacteria,1SK40@1236|Gammaproteobacteria,1JC1S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_1393343_8	641524.ADICYQ_1811	5.406e-09	57.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
CMS2_k127_1393343_3	388413.ALPR1_15804	1.122e-154	501.0	COG0726@1|root,COG0726@2|Bacteria,4NXDC@976|Bacteroidetes,47WVS@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS2_k127_1393343_5	880070.Cycma_4306	1.787e-83	286.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,47NNT@768503|Cytophagia	976|Bacteroidetes	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
CMS2_k127_1393343_0	216432.CA2559_12953	1.995e-263	818.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS2_k127_1393343_7	1034347.CAHJ01000091_gene1624	2.328e-29	124.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,1ZCV5@1386|Bacillus	91061|Bacilli	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS2_k127_1393343_2	616991.JPOO01000001_gene3356	7.81e-188	599.0	COG0477@1|root,COG0607@1|root,COG0607@2|Bacteria,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,1HZ4T@117743|Flavobacteriia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_1393343_6	266117.Rxyl_2941	5.453e-46	173.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
CMS2_k127_1393343_1	487796.Flav2ADRAFT_1518	2.113e-212	666.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,1HXU3@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1393343_4	1392488.JHZY01000004_gene2166	3.135e-129	419.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1HYV8@117743|Flavobacteriia,2XIMI@283735|Leeuwenhoekiella	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_1398856_5	1121896.JMLU01000027_gene606	4.296e-60	214.0	COG1913@1|root,COG1913@2|Bacteria,4NQPV@976|Bacteroidetes,1I73V@117743|Flavobacteriia,2NWJQ@237|Flavobacterium	976|Bacteroidetes	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
CMS2_k127_1398856_8	376686.Fjoh_3029	9.518e-33	129.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N,RE_NgoFVII
CMS2_k127_1398856_7	945713.IALB_2474	2.212e-33	138.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
CMS2_k127_1398856_11	1392490.JHZX01000001_gene2135	3.472e-18	91.0	28W88@1|root,2ZI8T@2|Bacteria,4P94M@976|Bacteroidetes,1IBM7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1398856_2	1121918.ARWE01000001_gene2688	1.983e-128	424.0	COG0476@1|root,COG0476@2|Bacteria,1PZJS@1224|Proteobacteria	1224|Proteobacteria	H	uBA THIF-type NAD FAD binding	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
CMS2_k127_1398856_14	324925.Ppha_1247	0.000134	47.0	COG2184@1|root,COG2184@2|Bacteria	2|Bacteria	D	nucleotidyltransferase activity	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
CMS2_k127_1398856_10	1189612.A33Q_3161	4.409e-26	109.0	COG2336@1|root,COG2336@2|Bacteria,4NSWY@976|Bacteroidetes	976|Bacteroidetes	T	Transcriptional regulator antitoxin, MazE	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
CMS2_k127_1398856_6	1492738.FEM21_07090	2.888e-42	156.0	COG2337@1|root,COG2337@2|Bacteria,4NQA9@976|Bacteroidetes,1ID3B@117743|Flavobacteriia,2NX4U@237|Flavobacterium	976|Bacteroidetes	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	mazF	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CMS2_k127_1398856_13	1341181.FLJC2902T_28230	1.049e-05	59.0	COG0265@1|root,COG3291@1|root,COG4675@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,COG4675@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2P0S7@237|Flavobacterium	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
CMS2_k127_1398856_12	1487953.JMKF01000088_gene5446	2.644e-16	93.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1G08F@1117|Cyanobacteria,1H8J6@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SBBP
CMS2_k127_1398856_9	324925.Ppha_1247	8.19e-31	123.0	COG2184@1|root,COG2184@2|Bacteria	2|Bacteria	D	nucleotidyltransferase activity	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
CMS2_k127_1398856_0	1121875.KB907546_gene2691	2.127e-186	598.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1I0MT@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS2_k127_1398856_1	1121904.ARBP01000004_gene786	1.432e-128	424.0	COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,47K9E@768503|Cytophagia	976|Bacteroidetes	S	Kelch repeat	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
CMS2_k127_1398856_4	1168034.FH5T_06985	5.344e-96	318.0	COG0702@1|root,COG0702@2|Bacteria,4NGMR@976|Bacteroidetes	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS2_k127_1398856_3	398720.MED217_14185	2.337e-117	386.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,1I0ZQ@117743|Flavobacteriia,2XJWX@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
CMS2_k127_144312_0	1237149.C900_04426	1.785e-79	304.0	COG1404@1|root,COG2133@1|root,COG2374@1|root,COG3291@1|root,COG3468@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia	976|Bacteroidetes	Q	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PKD
CMS2_k127_144312_4	1121904.ARBP01000007_gene3005	5.392e-13	85.0	COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG3420@1|root,COG4733@1|root,COG4886@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4PHVF@976|Bacteroidetes,47SD5@768503|Cytophagia	976|Bacteroidetes	P	Leucine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,Laminin_G_3,VCBS
CMS2_k127_144312_3	1237149.C900_04425	1.124e-16	92.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS2_k127_144312_2	313606.M23134_02455	6.462e-21	105.0	COG3047@1|root,COG3047@2|Bacteria,4PM1M@976|Bacteroidetes,47XZM@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_144312_1	1237149.C900_04423	2.979e-52	199.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes,47NKP@768503|Cytophagia	976|Bacteroidetes	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS2_k127_1464822_5	1250232.JQNJ01000001_gene3794	5.186e-182	575.0	COG1649@1|root,COG1649@2|Bacteria,4NGFW@976|Bacteroidetes,1HYGF@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
CMS2_k127_1464822_4	1121904.ARBP01000060_gene1918	2.05e-184	583.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,47JGE@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1464822_0	1237149.C900_01776	0.0	1345.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,47K29@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
CMS2_k127_1464822_6	1279009.ADICEAN_01735	5.789e-177	569.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS2_k127_1464822_13	1121904.ARBP01000001_gene5925	2.775e-118	388.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47KNZ@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_1464822_25	926549.KI421517_gene1208	1.399e-35	143.0	COG2867@1|root,COG2867@2|Bacteria,4NNHS@976|Bacteroidetes,47P7J@768503|Cytophagia	976|Bacteroidetes	I	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
CMS2_k127_1464822_11	411154.GFO_3615	7.213e-127	412.0	COG3000@1|root,COG3000@2|Bacteria,4NI60@976|Bacteroidetes,1HX0M@117743|Flavobacteriia	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_1464822_26	1168034.FH5T_19660	1.752e-27	120.0	2BNB7@1|root,32GYU@2|Bacteria,4NQDS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1464822_8	929562.Emtol_2583	5.374e-136	445.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_1464822_22	1237149.C900_02737	3.883e-48	181.0	COG3595@1|root,COG3595@2|Bacteria,4NR7Q@976|Bacteroidetes,47XVG@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_1464822_12	1237149.C900_02725	2.716e-118	391.0	COG2067@1|root,COG2067@2|Bacteria,4PKQK@976|Bacteroidetes,47XZ1@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1464822_20	1237149.C900_02724	1.308e-64	228.0	COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,47PKF@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS2_k127_1464822_14	1089547.KB913013_gene2630	1.542e-105	347.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,47MC0@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS2_k127_1464822_2	1237149.C900_02722	0.0	1174.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,47JEC@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS2_k127_1464822_21	1237149.C900_02721	1.372e-64	225.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,47PD1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS2_k127_1464822_23	1237149.C900_02720	5.665e-47	174.0	COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS2_k127_1464822_19	153721.MYP_4827	3.48e-66	236.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,47KS4@768503|Cytophagia	976|Bacteroidetes	V	peptidase U61 LD-carboxypeptidase A	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
CMS2_k127_1464822_1	1121904.ARBP01000004_gene917	0.0	1237.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,4NFBV@976|Bacteroidetes,47K85@768503|Cytophagia	976|Bacteroidetes	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS2_k127_1464822_17	1123277.KB893194_gene5825	3.122e-83	287.0	COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes,47MCV@768503|Cytophagia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
CMS2_k127_1464822_24	1237149.C900_04497	6.874e-40	153.0	COG2318@1|root,COG2318@2|Bacteria,4NSP0@976|Bacteroidetes,47R5Z@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CMS2_k127_1464822_9	313598.MED152_05725	4.335e-129	418.0	COG0673@1|root,COG0673@2|Bacteria,4PI4T@976|Bacteroidetes,1HY7Z@117743|Flavobacteriia,3VWC3@52959|Polaribacter	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1464822_10	1408473.JHXO01000010_gene3756	6.501e-129	422.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,2FNQP@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
CMS2_k127_1464822_16	1453500.AT05_02455	4.944e-91	303.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1HZ0I@117743|Flavobacteriia	976|Bacteroidetes	S	Hexapeptide transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
CMS2_k127_1464822_7	1124780.ANNU01000005_gene2419	2.362e-149	481.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47KX7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS2_k127_1464822_3	643867.Ftrac_2667	5.283e-204	641.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,47JKM@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS2_k127_1464822_15	1191523.MROS_1166	3.816e-97	336.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS2_k127_1464822_18	926562.Oweho_3469	2.377e-75	256.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia,2PBG9@246874|Cryomorphaceae	976|Bacteroidetes	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
CMS2_k127_152642_14	880070.Cycma_1762	9.409e-95	321.0	COG4251@1|root,COG4251@2|Bacteria,4NHEM@976|Bacteroidetes,47QEB@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154,HATPase_c,HisKA,PAS,PAS_9
CMS2_k127_152642_1	1237149.C900_00745	0.0	1034.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,47KBD@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
CMS2_k127_152642_11	926562.Oweho_2780	4.778e-117	392.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia,2PBC1@246874|Cryomorphaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_152642_7	926562.Oweho_2781	9.115e-182	578.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia,2PBC9@246874|Cryomorphaceae	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
CMS2_k127_152642_8	926562.Oweho_2782	5.781e-175	566.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia,2PBEV@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS2_k127_152642_19	1408433.JHXV01000025_gene4041	1.482e-74	261.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,1HZEU@117743|Flavobacteriia,2PBD7@246874|Cryomorphaceae	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_152642_13	313603.FB2170_01357	7.74e-95	327.0	COG0330@1|root,COG0330@2|Bacteria,4NHJA@976|Bacteroidetes,1HZ37@117743|Flavobacteriia	976|Bacteroidetes	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS2_k127_152642_16	997296.PB1_12094	7.101e-85	286.0	COG4430@1|root,COG4430@2|Bacteria,1UYP9@1239|Firmicutes,4HDZD@91061|Bacilli,1ZDB7@1386|Bacillus	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	ydeI	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
CMS2_k127_152642_9	929713.NIASO_00660	9.421e-151	484.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,1INPE@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
CMS2_k127_152642_15	1443665.JACA01000034_gene2449	1.455e-86	292.0	COG2067@1|root,COG2067@2|Bacteria,4NGWZ@976|Bacteroidetes,1IJ7F@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CMS2_k127_152642_12	1250005.PHEL85_2317	3.067e-95	315.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia,3VW5G@52959|Polaribacter	976|Bacteroidetes	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS2_k127_152642_5	1296415.JACC01000050_gene1791	1.006e-210	666.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia,2YI8N@290174|Aquimarina	976|Bacteroidetes	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
CMS2_k127_152642_17	1347342.BN863_15090	1.702e-80	284.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,1HXGB@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS2_k127_152642_18	1286632.P278_03850	7.488e-78	267.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,1IMIZ@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_152642_2	1137281.D778_01514	2.919e-284	886.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,1HXGN@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS2_k127_152642_24	1286632.P278_03730	4.249e-05	47.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1I08M@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_152642_25	313603.FB2170_12971	7.814e-05	47.0	COG2207@1|root,COG2207@2|Bacteria,4NPH9@976|Bacteroidetes,1I1ZC@117743|Flavobacteriia,2PHTG@252356|Maribacter	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_152642_4	1380600.AUYN01000009_gene1244	3.921e-229	719.0	COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,1HYF8@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
CMS2_k127_152642_10	1121904.ARBP01000003_gene6268	1.382e-132	428.0	COG1409@1|root,COG1409@2|Bacteria,4NKP0@976|Bacteroidetes	976|Bacteroidetes	G	Calcineurin-like phosphoesterase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Metallophos,SASA
CMS2_k127_152642_22	531844.FIC_01835	2.022e-13	72.0	COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
CMS2_k127_152642_23	926556.Echvi_1400	2.716e-11	70.0	2DTFB@1|root,33K42@2|Bacteria,4NZPM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_152642_6	926556.Echvi_1401	5.828e-200	628.0	COG1538@1|root,COG1538@2|Bacteria,4NIE8@976|Bacteroidetes,47TA2@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_152642_21	926556.Echvi_1402	1.541e-20	93.0	2A933@1|root,30Y75@2|Bacteria,4PBYM@976|Bacteroidetes,47WIT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_152642_3	926556.Echvi_1403	5.351e-282	871.0	COG0845@1|root,COG0845@2|Bacteria,4NF6Y@976|Bacteroidetes,47SUU@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
CMS2_k127_152642_0	926556.Echvi_1404	0.0	1796.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JFH@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS2_k127_1647184_0	866536.Belba_0241	4.921e-248	798.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47XZE@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1647184_1	866536.Belba_0240	2.676e-69	251.0	COG2913@1|root,COG2913@2|Bacteria,4PMPG@976|Bacteroidetes,47N3C@768503|Cytophagia	976|Bacteroidetes	J	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_1783967_0	1121904.ARBP01000002_gene7111	3.04e-240	752.0	COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47MR5@768503|Cytophagia	976|Bacteroidetes	E	RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_1783967_1	1121904.ARBP01000002_gene7112	2.6e-186	589.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JHW@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1906424_1	1168034.FH5T_10340	2.54e-126	411.0	COG3177@1|root,COG3177@2|Bacteria,4NHPW@976|Bacteroidetes,2FQXS@200643|Bacteroidia	976|Bacteroidetes	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
CMS2_k127_1906424_4	349521.HCH_00833	0.000877	44.0	COG1073@1|root,COG1073@2|Bacteria,1RCY0@1224|Proteobacteria,1SZ5J@1236|Gammaproteobacteria,1XQRF@135619|Oceanospirillales	135619|Oceanospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS2_k127_1906424_2	1317122.ATO12_09275	3.59e-109	364.0	2DBJ5@1|root,2Z9IG@2|Bacteria,4NI72@976|Bacteroidetes,1I06W@117743|Flavobacteriia,2YIZX@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1906424_0	509635.N824_13940	6.786e-136	439.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1IRN3@117747|Sphingobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS2_k127_1906424_3	866536.Belba_1477	1.054e-82	281.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,47JB4@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS2_k127_1948393_0	1121904.ARBP01000019_gene2721	0.0	1026.0	COG0823@1|root,COG1262@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,47N2Q@768503|Cytophagia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS2_k127_1948393_2	643867.Ftrac_3376	1.019e-05	53.0	2EG8H@1|root,33A0B@2|Bacteria,4NY1M@976|Bacteroidetes,47SNZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2001374_1	313606.M23134_07613	5.909e-255	812.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47KVA@768503|Cytophagia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_2001374_3	518766.Rmar_2506	3.836e-102	348.0	COG0521@1|root,COG0521@2|Bacteria,4NHZS@976|Bacteroidetes	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like,SusD-like_2,SusD_RagB
CMS2_k127_2001374_0	1122176.KB903532_gene2674	0.0	1034.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,1IW0D@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_2001374_2	760192.Halhy_4561	8.092e-134	446.0	COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,1IW8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
CMS2_k127_2001374_4	1122176.KB903532_gene2672	0.0006003	48.0	2AM3F@1|root,31BXJ@2|Bacteria,4NPAN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_208931_9	643867.Ftrac_2823	1.072e-07	59.0	2EPSB@1|root,33HCU@2|Bacteria,4NYPB@976|Bacteroidetes,47SU9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_208931_7	1237149.C900_05472	6.509e-25	108.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,47RZJ@768503|Cytophagia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS2_k127_208931_3	643867.Ftrac_2035	3.528e-131	423.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,47MCF@768503|Cytophagia	976|Bacteroidetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
CMS2_k127_208931_0	1379270.AUXF01000001_gene1915	1.724e-219	691.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	CP_0318	-	-	ko:K06131,ko:K06132	ko00564,ko01100,map00564,map01100	-	R07390,R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS2_k127_208931_4	1380600.AUYN01000001_gene2643	4.853e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,4NH6Y@976|Bacteroidetes,1HXA4@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_208931_2	1144313.PMI10_03174	1.095e-131	425.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1HYU7@117743|Flavobacteriia,2NSWE@237|Flavobacterium	976|Bacteroidetes	Q	Ureidoglycolate lyase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS2_k127_208931_6	1121904.ARBP01000003_gene6192	2.098e-92	310.0	COG3618@1|root,COG3618@2|Bacteria,4NFGB@976|Bacteroidetes,47JKH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS2_k127_208931_5	1123057.P872_12500	3.318e-94	316.0	COG1028@1|root,COG1028@2|Bacteria,4NH6R@976|Bacteroidetes,47KYG@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K18333	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_208931_1	1127673.GLIP_0468	2.672e-136	445.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,4659F@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
CMS2_k127_208931_8	1453498.LG45_05260	1.957e-15	81.0	2C6MD@1|root,32ZRJ@2|Bacteria,4NVYE@976|Bacteroidetes,1I5BT@117743|Flavobacteriia,2NX57@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_210275_11	1128427.KB904821_gene1758	6.179e-42	161.0	COG3457@1|root,COG3457@2|Bacteria,1G485@1117|Cyanobacteria,1HA6G@1150|Oscillatoriales	1117|Cyanobacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
CMS2_k127_210275_3	1121007.AUML01000006_gene3132	4.109e-153	491.0	COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,1HZA0@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
CMS2_k127_210275_14	1168034.FH5T_15540	1.008e-14	75.0	2DFUX@1|root,2ZT8Y@2|Bacteria,4P92B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_210275_9	1120965.AUBV01000013_gene1342	3.354e-88	294.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,47PAR@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_210275_4	1237149.C900_04276	3.042e-143	479.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_210275_2	391603.FBALC1_01182	9.997e-154	495.0	COG0025@1|root,COG0025@2|Bacteria,4NF54@976|Bacteroidetes,1HYT6@117743|Flavobacteriia	976|Bacteroidetes	P	sodium proton antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS2_k127_210275_10	177437.HRM2_44880	1.003e-69	245.0	COG0454@1|root,COG0456@2|Bacteria,1RA90@1224|Proteobacteria,42QTT@68525|delta/epsilon subdivisions,2WMN9@28221|Deltaproteobacteria,2MJTM@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.264	ko:K21935	-	-	R11701	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
CMS2_k127_210275_1	290318.Cvib_1366	3.715e-157	508.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_210275_0	1123368.AUIS01000030_gene1244	1.672e-186	595.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
CMS2_k127_210275_12	886379.AEWI01000208_gene2430	4.082e-39	151.0	COG1846@1|root,COG1846@2|Bacteria,4NRNH@976|Bacteroidetes,2G26Q@200643|Bacteroidia,3XK68@558415|Marinilabiliaceae	976|Bacteroidetes	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS2_k127_210275_7	643867.Ftrac_2683	9.142e-110	362.0	COG0061@1|root,COG0061@2|Bacteria,4NG3P@976|Bacteroidetes,47M9J@768503|Cytophagia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
CMS2_k127_210275_6	1279009.ADICEAN_00872	2.015e-134	436.0	COG0330@1|root,COG0330@2|Bacteria,4NHKT@976|Bacteroidetes,47Q4F@768503|Cytophagia	976|Bacteroidetes	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS2_k127_210275_8	1279009.ADICEAN_00873	2.455e-108	354.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,47P8V@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS2_k127_210275_5	700598.Niako_4146	2.918e-136	445.0	COG0477@1|root,COG2814@2|Bacteria,4NG6X@976|Bacteroidetes,1IP4F@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Drug resistance transporter Bcr CflA subfamily	-	-	-	ko:K03446,ko:K07552	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.2,2.A.1.3	-	-	MFS_1
CMS2_k127_210275_15	1305737.JAFX01000001_gene1594	2.047e-08	56.0	COG2337@1|root,COG2337@2|Bacteria,4NYKT@976|Bacteroidetes	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CMS2_k127_210275_13	929562.Emtol_0738	2.424e-38	148.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,47JY8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS2_k127_2202458_13	1237149.C900_04345	2.109e-20	91.0	2BVK8@1|root,32Y0S@2|Bacteria,4NUUA@976|Bacteroidetes,47RXH@768503|Cytophagia	976|Bacteroidetes	S	Histone H1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hc1
CMS2_k127_2202458_0	1237149.C900_04344	1.702e-208	653.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,47KDV@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_2202458_8	886377.Murru_0931	5.298e-86	291.0	COG4221@1|root,COG4221@2|Bacteria,4PKIR@976|Bacteroidetes,1IJAA@117743|Flavobacteriia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_2202458_1	1305737.JAFX01000001_gene1163	2.296e-192	614.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS2_k127_2202458_2	1237149.C900_04342	4.446e-188	596.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,47NI5@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CMS2_k127_2202458_10	1048983.EL17_17370	2.241e-51	187.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,47JTY@768503|Cytophagia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS2_k127_2202458_9	387093.SUN_1550	1.109e-68	246.0	COG0554@1|root,COG0554@2|Bacteria,1PBI5@1224|Proteobacteria,42UC4@68525|delta/epsilon subdivisions,2YTEA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4-alpha-L-fucosyltransferase glycosyl transferase group 56	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_56
CMS2_k127_2202458_3	1517682.HW49_00730	1.793e-174	553.0	COG0399@1|root,COG0399@2|Bacteria,4NEIU@976|Bacteroidetes,2FPX9@200643|Bacteroidia,22ZF6@171551|Porphyromonadaceae	976|Bacteroidetes	E	COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS2_k127_2202458_12	880071.Fleli_1537	3.093e-36	146.0	COG0454@1|root,COG0456@2|Bacteria,4NTKC@976|Bacteroidetes,47SAX@768503|Cytophagia	976|Bacteroidetes	K	FR47-like protein	-	-	2.3.1.210	ko:K16704	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS2_k127_2202458_11	1137281.D778_02596	2.916e-37	150.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
CMS2_k127_2202458_6	886379.AEWI01000014_gene1414	1.084e-104	349.0	COG1215@1|root,COG1215@2|Bacteria,4NFUA@976|Bacteroidetes,2FPUN@200643|Bacteroidia,3XKCY@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
CMS2_k127_2202458_4	1237149.C900_04333	5.625e-162	521.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,47JF4@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
CMS2_k127_2202458_5	1237149.C900_04332	2.801e-135	445.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS2_k127_2202458_7	1124780.ANNU01000003_gene1402	1.433e-101	334.0	COG1760@1|root,COG1760@2|Bacteria,4NFXU@976|Bacteroidetes,47MYT@768503|Cytophagia	976|Bacteroidetes	E	Serine dehydratase beta chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_beta
CMS2_k127_2205603_9	745718.JADT01000026_gene525	2.111e-142	460.0	COG1305@1|root,COG1305@2|Bacteria,4NPWW@976|Bacteroidetes	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS2_k127_2205603_4	1237149.C900_03940	1.248e-226	711.0	COG0733@1|root,COG0733@2|Bacteria,4P0HG@976|Bacteroidetes,47XNW@768503|Cytophagia	976|Bacteroidetes	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
CMS2_k127_2205603_17	391587.KAOT1_13547	4.487e-31	128.0	2EDNQ@1|root,337IF@2|Bacteria,4NW0N@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
CMS2_k127_2205603_15	1250232.JQNJ01000001_gene450	5.612e-65	232.0	2DBQG@1|root,2ZADX@2|Bacteria,4PKKS@976|Bacteroidetes,1I1VX@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_2205603_0	1123278.KB893455_gene780	0.0	1099.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_2205603_7	760192.Halhy_5728	5.275e-162	523.0	COG0521@1|root,COG0521@2|Bacteria,4NHNF@976|Bacteroidetes,1IP72@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
CMS2_k127_2205603_23	1166018.FAES_5061	2.601e-10	70.0	2A2ZH@1|root,30RE0@2|Bacteria,4NP88@976|Bacteroidetes,47Q4Z@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
CMS2_k127_2205603_16	1121904.ARBP01000009_gene4183	2.607e-36	138.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,47R5P@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS2_k127_2205603_5	643867.Ftrac_0960	8.7e-190	603.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,47MY8@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS2_k127_2205603_8	1313421.JHBV01000049_gene20	7.513e-148	491.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1J0XQ@117747|Sphingobacteriia	976|Bacteroidetes	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2205603_3	1124780.ANNU01000006_gene2955	1.53e-253	811.0	COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes,47Y3I@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_2205603_11	1237149.C900_01524	8.307e-112	373.0	COG0520@1|root,COG0520@2|Bacteria,4NJ4E@976|Bacteroidetes,47MW6@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_2205603_1	1121904.ARBP01000001_gene5338	9.037e-315	977.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_2205603_20	1121904.ARBP01000001_gene5493	2.019e-16	91.0	28IM1@1|root,2Z8MK@2|Bacteria,4NIZ0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2205603_12	269798.CHU_0303	5.027e-108	353.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,47MBG@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	yadF	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS2_k127_2205603_19	714943.Mucpa_0753	1.541e-24	108.0	2ED5Q@1|root,3372E@2|Bacteria,4NUVW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2205603_22	313595.P700755_001759	1.677e-11	66.0	28J1N@1|root,2Z8YI@2|Bacteria,4NH1X@976|Bacteroidetes,1I0QB@117743|Flavobacteriia,4C43A@83612|Psychroflexus	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS2_k127_2205603_14	555500.I215_08571	3.269e-67	233.0	COG0664@1|root,COG0664@2|Bacteria,4NKGK@976|Bacteroidetes,1I2MF@117743|Flavobacteriia	976|Bacteroidetes	T	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS2_k127_2205603_13	1313421.JHBV01000031_gene1345	4.48e-97	322.0	COG3967@1|root,COG3967@2|Bacteria,4NJDN@976|Bacteroidetes,1IS2M@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
CMS2_k127_2205603_2	880070.Cycma_1169	4.633e-259	802.0	COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,47N9X@768503|Cytophagia	976|Bacteroidetes	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
CMS2_k127_2205603_6	880070.Cycma_1168	1.829e-182	574.0	COG2378@1|root,COG2378@2|Bacteria,4NGHM@976|Bacteroidetes,47MP3@768503|Cytophagia	976|Bacteroidetes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	PhyH,WYL
CMS2_k127_2205603_24	1193181.BN10_140045	9.954e-08	62.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria,4FJ7Y@85021|Intrasporangiaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS2_k127_2205603_10	867900.Celly_1480	1.66e-115	377.0	2CAD1@1|root,2Z81J@2|Bacteria,4NJ4C@976|Bacteroidetes,1I0Q2@117743|Flavobacteriia,1F95S@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2205603_25	869213.JCM21142_134717	0.0001479	46.0	COG3177@1|root,COG3177@2|Bacteria,4NFBY@976|Bacteroidetes,47MWT@768503|Cytophagia	976|Bacteroidetes	K	PFAM Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
CMS2_k127_2205603_18	1239962.C943_00321	4.84e-29	117.0	2AVPC@1|root,31MGE@2|Bacteria,4NQFW@976|Bacteroidetes,47R5H@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2283732_4	1089550.ATTH01000001_gene669	3.966e-156	516.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
CMS2_k127_2283732_2	1120966.AUBU01000013_gene470	1.066e-190	612.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,47M7Z@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_2283732_5	504487.JCM19302_2894	6.494e-131	426.0	COG3828@1|root,COG3828@2|Bacteria,4NFMU@976|Bacteroidetes,1HYYM@117743|Flavobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS2_k127_2283732_3	1120965.AUBV01000007_gene2630	6.981e-189	599.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,47THD@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_2283732_6	929556.Solca_3964	4.653e-127	430.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,1IQ3M@117747|Sphingobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_2283732_0	1121930.AQXG01000012_gene3213	0.0	1293.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,1IVI6@117747|Sphingobacteriia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS2_k127_2283732_7	1408433.JHXV01000033_gene1169	1.978e-81	277.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia,2PB38@246874|Cryomorphaceae	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
CMS2_k127_2283732_8	1286632.P278_03700	1.037e-79	270.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1I33C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_2283732_10	1347368.HG964404_gene5394	3.257e-36	145.0	COG1413@1|root,COG1413@2|Bacteria,1VTQX@1239|Firmicutes,4HTH7@91061|Bacilli	91061|Bacilli	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2283732_1	1123234.AUKI01000023_gene1970	2.154e-302	938.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_2283732_12	1122179.KB890449_gene132	1.028e-05	60.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_2283732_11	1121904.ARBP01000077_gene4901	3.286e-11	78.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_2283732_9	388413.ALPR1_10310	3.943e-77	258.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,47JZU@768503|Cytophagia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS2_k127_229290_6	1237149.C900_05268	2.124e-240	797.0	COG0419@1|root,COG0419@2|Bacteria,4NGQP@976|Bacteroidetes,47MNH@768503|Cytophagia	976|Bacteroidetes	L	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_32	153721.MYP_4062	2.48e-71	265.0	COG4733@1|root,COG4733@2|Bacteria,4NF53@976|Bacteroidetes,47MWJ@768503|Cytophagia	976|Bacteroidetes	S	SPTR Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_17	1185876.BN8_00772	2.465e-121	442.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB,TIG
CMS2_k127_229290_26	643867.Ftrac_2997	1.199e-87	329.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NRDH@976|Bacteroidetes	976|Bacteroidetes	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_229290_58	748280.NH8B_1021	1.088e-10	74.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,2KPN9@206351|Neisseriales	206351|Neisseriales	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,Rick_17kDa_Anti
CMS2_k127_229290_50	1237149.C900_05263	8.421e-34	148.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_49	313606.M23134_08192	1.838e-34	155.0	COG3179@1|root,COG3179@2|Bacteria,4NF8K@976|Bacteroidetes,47Q6C@768503|Cytophagia	976|Bacteroidetes	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CMS2_k127_229290_42	1237149.C900_05266	2.991e-48	194.0	COG4733@1|root,COG4733@2|Bacteria,4NWW8@976|Bacteroidetes,47VMK@768503|Cytophagia	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_45	1237149.C900_04357	7.358e-42	157.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,47Q5Z@768503|Cytophagia	976|Bacteroidetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS2_k127_229290_37	1237149.C900_04356	4.446e-64	240.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,47M7Q@768503|Cytophagia	976|Bacteroidetes	KMT	PFAM BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
CMS2_k127_229290_7	1237149.C900_04723	1.446e-221	691.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_229290_16	926556.Echvi_0146	2.015e-125	408.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,47JUZ@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS2_k127_229290_46	1121904.ARBP01000019_gene2720	8.088e-41	166.0	COG2353@1|root,COG2353@2|Bacteria,4PPMU@976|Bacteroidetes,47YPD@768503|Cytophagia	2|Bacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_24	1124780.ANNU01000028_gene991	3.549e-93	312.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS2_k127_229290_15	1124780.ANNU01000028_gene992	6.311e-131	434.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,47MQE@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CMS2_k127_229290_12	1237149.C900_04713	5.992e-164	533.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,47KE1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CMS2_k127_229290_44	761193.Runsl_0815	1.57e-45	174.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
CMS2_k127_229290_20	1237149.C900_04711	2.298e-107	362.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,47JWJ@768503|Cytophagia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_229290_53	1237149.C900_04710	8.467e-27	110.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,47S09@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS2_k127_229290_11	1237149.C900_04708	1.217e-166	535.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,47KJK@768503|Cytophagia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS2_k127_229290_23	1237149.C900_04707	1.526e-94	321.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,47NDQ@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
CMS2_k127_229290_2	1237149.C900_04706	0.0	1103.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,47JSR@768503|Cytophagia	976|Bacteroidetes	C	Phosphate acetyl butaryl transferase	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS2_k127_229290_31	1237149.C900_04705	1.054e-74	255.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,47N8D@768503|Cytophagia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS2_k127_229290_0	1237149.C900_04704	0.0	2945.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,47K4H@768503|Cytophagia	976|Bacteroidetes	D	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CMS2_k127_229290_40	746697.Aeqsu_0885	3.083e-54	193.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS2_k127_229290_56	742817.HMPREF9449_02788	5.314e-15	79.0	COG5652@1|root,COG5652@2|Bacteria,4PA3X@976|Bacteroidetes,2FVHF@200643|Bacteroidia	976|Bacteroidetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS2_k127_229290_22	1237149.C900_04701	3.755e-97	321.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_229290_13	1237149.C900_04691	1.98e-152	491.0	COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,47JQS@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CMS2_k127_229290_48	929556.Solca_1361	3.291e-37	145.0	2CD0I@1|root,30JWK@2|Bacteria,4P4YR@976|Bacteroidetes,1IY9W@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
CMS2_k127_229290_41	1279009.ADICEAN_01214	2.206e-52	192.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS2_k127_229290_39	1237149.C900_01031	2.081e-57	212.0	COG3827@1|root,COG3827@2|Bacteria,4PMMQ@976|Bacteroidetes,47Y53@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_14	1124780.ANNU01000005_gene2403	5.08e-141	460.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,47JVQ@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS2_k127_229290_4	1237149.C900_01029	1.153e-263	823.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,47JSM@768503|Cytophagia	976|Bacteroidetes	M	Penicillin-binding protein, dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS2_k127_229290_51	1121859.KB890738_gene3182	1.524e-32	132.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,47R21@768503|Cytophagia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_33	1237149.C900_01027	8.206e-70	245.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,47KWQ@768503|Cytophagia	976|Bacteroidetes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS2_k127_229290_9	1237149.C900_01026	4.705e-205	640.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,47JQ4@768503|Cytophagia	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS2_k127_229290_8	643867.Ftrac_2257	1.462e-216	682.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,47JQT@768503|Cytophagia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS2_k127_229290_38	504472.Slin_4818	3.127e-61	216.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,47KTP@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS2_k127_229290_34	643867.Ftrac_2481	5.023e-69	244.0	COG0382@1|root,COG0382@2|Bacteria,4NGNA@976|Bacteroidetes,47MCK@768503|Cytophagia	976|Bacteroidetes	H	PFAM UbiA prenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_229290_3	1237149.C900_01022	4.645e-264	841.0	COG4772@1|root,COG4772@2|Bacteria,4PKTE@976|Bacteroidetes,47KHE@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_229290_52	313606.M23134_07928	6.285e-27	115.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia	976|Bacteroidetes	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
CMS2_k127_229290_19	1237149.C900_01019	3.288e-117	380.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,47JC6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS2_k127_229290_29	1237149.C900_01018	7.515e-79	267.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,47P9Z@768503|Cytophagia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS2_k127_229290_10	1237149.C900_01015	1.634e-179	593.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_229290_30	1189612.A33Q_0540	2.858e-75	256.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,47JKF@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS2_k127_229290_36	1121129.KB903360_gene3561	2.251e-66	231.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,2FNWA@200643|Bacteroidia,22XMY@171551|Porphyromonadaceae	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS2_k127_229290_59	866536.Belba_0436	2.387e-09	62.0	2EK82@1|root,33DYE@2|Bacteria,4NYF0@976|Bacteroidetes,47SMK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS2_k127_229290_21	1237149.C900_01010	3.325e-97	319.0	COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,47JFG@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_229290_27	1237149.C900_03775	1.278e-86	299.0	COG4192@1|root,COG4192@2|Bacteria,4NFY7@976|Bacteroidetes,47MMQ@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
CMS2_k127_229290_1	1237149.C900_05718	0.0	1403.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_229290_18	1237149.C900_01981	6.8e-121	399.0	COG1215@1|root,COG1215@2|Bacteria,4NEG0@976|Bacteroidetes,47KET@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS2_k127_229290_25	1237149.C900_01982	1.463e-91	332.0	COG2911@1|root,COG3210@1|root,COG3637@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	oprH	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	OMP_b-brl,fn3
CMS2_k127_229290_60	700598.Niako_5175	1.079e-06	60.0	COG0226@1|root,COG0226@2|Bacteria,4PKPM@976|Bacteroidetes,1J0SY@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_229290_35	1237149.C900_01985	1.628e-68	248.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_229290_43	1121904.ARBP01000018_gene2694	4.722e-48	179.0	COG0560@1|root,COG0560@2|Bacteria,4NRRM@976|Bacteroidetes,47VIZ@768503|Cytophagia	976|Bacteroidetes	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,HAD
CMS2_k127_229290_28	1237149.C900_04195	6.981e-81	278.0	COG0382@1|root,COG0382@2|Bacteria,4NIRK@976|Bacteroidetes,47SWZ@768503|Cytophagia	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS2_k127_229290_57	391587.KAOT1_06302	2.886e-13	75.0	2CH0Y@1|root,3309M@2|Bacteria,4NY17@976|Bacteroidetes,1I6TX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_55	1434325.AZQN01000003_gene2799	5.706e-17	81.0	2EGPU@1|root,33AFZ@2|Bacteria,4NXYH@976|Bacteroidetes,47S90@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_229290_5	1121481.AUAS01000001_gene4532	6.516e-256	797.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS2_k127_2350544_5	926549.KI421517_gene3543	3.61e-74	261.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,47N5M@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the ABC transporter superfamily	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS2_k127_2350544_0	1453498.LG45_09280	0.0	1017.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,1HZ18@117743|Flavobacteriia,2NSWK@237|Flavobacterium	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS2_k127_2350544_8	1408433.JHXV01000008_gene58	2.632e-49	178.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,1I3D1@117743|Flavobacteriia,2PBSB@246874|Cryomorphaceae	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CMS2_k127_2350544_2	929556.Solca_3181	1.019e-140	460.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,1IPVT@117747|Sphingobacteriia	976|Bacteroidetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS2_k127_2350544_10	1121904.ARBP01000010_gene2239	5.087e-31	124.0	COG3288@1|root,COG3288@2|Bacteria,4NT78@976|Bacteroidetes,47RF1@768503|Cytophagia	976|Bacteroidetes	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
CMS2_k127_2350544_4	866536.Belba_3466	2.06e-101	343.0	COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,47KX8@768503|Cytophagia	976|Bacteroidetes	C	Alanine dehydrogenase/PNT, C-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS2_k127_2350544_6	1267535.KB906767_gene661	1.579e-66	241.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
CMS2_k127_2350544_7	886377.Murru_1936	1.399e-49	181.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,1I340@117743|Flavobacteriia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS2_k127_2350544_9	1356852.N008_09720	4.447e-31	130.0	2DYGZ@1|root,32V5E@2|Bacteria,4NSGC@976|Bacteroidetes,47SKW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3575)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
CMS2_k127_2350544_11	865937.Gilli_2304	5.388e-25	108.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
CMS2_k127_2350544_1	1121875.KB907548_gene1482	4.175e-167	536.0	COG1305@1|root,COG1305@2|Bacteria,4NKII@976|Bacteroidetes,1HZX3@117743|Flavobacteriia	976|Bacteroidetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS2_k127_2350544_3	41431.PCC8801_1140	3.277e-117	412.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3KH9M@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg,dCache_1
CMS2_k127_2424673_11	1137281.D778_00006	2.244e-71	250.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_2424673_22	880070.Cycma_2047	0.0002902	47.0	COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,47MS7@768503|Cytophagia	976|Bacteroidetes	S	PFAM amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_2424673_17	616991.JPOO01000003_gene2354	1.838e-17	85.0	COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,1I06U@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS2_k127_2424673_5	313603.FB2170_04530	8.822e-149	480.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia,2PGR5@252356|Maribacter	976|Bacteroidetes	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS2_k127_2424673_0	760192.Halhy_3998	1.418e-290	902.0	COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS2_k127_2424673_6	566466.NOR53_1326	1.733e-143	471.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1SK5X@1236|Gammaproteobacteria,1J8FM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_2424673_4	1121859.KB890738_gene3403	2.469e-161	536.0	COG4773@1|root,COG4773@2|Bacteria,4PP9G@976|Bacteroidetes,47YJ3@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_2424673_13	1121373.KB903624_gene2422	9.679e-54	205.0	2BUNJ@1|root,32PZE@2|Bacteria,4NQFC@976|Bacteroidetes,47VU5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2424673_8	1250232.JQNJ01000001_gene1986	3.765e-84	284.0	COG2940@1|root,COG2940@2|Bacteria,4NM5I@976|Bacteroidetes,1I1ME@117743|Flavobacteriia	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
CMS2_k127_2424673_9	1189612.A33Q_4372	1.251e-77	267.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,47N4G@768503|Cytophagia	976|Bacteroidetes	H	PFAM Tetrapyrrole (Corrin Porphyrin) Methylases	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS2_k127_2424673_3	1229487.AMYW01000019_gene2312	4.881e-215	673.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1HX18@117743|Flavobacteriia,2NSI7@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS2_k127_2424673_10	1189612.A33Q_0655	1.775e-77	278.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,47K28@768503|Cytophagia	976|Bacteroidetes	I	PFAM Outer membrane protein transport protein (OMPP1 FadL TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
CMS2_k127_2424673_16	1237149.C900_04730	5.247e-19	101.0	2CJG0@1|root,332HN@2|Bacteria,4NM27@976|Bacteroidetes,47M0N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2424673_1	1120965.AUBV01000001_gene3475	1.665e-268	831.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,47JTQ@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
CMS2_k127_2424673_2	1237149.C900_00798	1.308e-243	777.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,47JKP@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
CMS2_k127_2424673_14	1121373.KB903621_gene1916	9.883e-41	156.0	2CH1A@1|root,348NH@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS2_k127_2424673_12	1048983.EL17_09275	4.764e-61	218.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,47QCG@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS2_k127_2424673_15	1450525.JATV01000001_gene2575	3.192e-32	137.0	2DEWG@1|root,2ZPIW@2|Bacteria,4PMSE@976|Bacteroidetes,1I2HM@117743|Flavobacteriia,2NWP5@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2424673_20	421072.IO89_12030	1.654e-08	61.0	2FFNF@1|root,347JU@2|Bacteria,4P6PZ@976|Bacteroidetes,1IA77@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2424673_18	1349785.BAUG01000058_gene2528	2.345e-17	85.0	2DP84@1|root,330YJ@2|Bacteria,4NV1T@976|Bacteroidetes,1I5CN@117743|Flavobacteriia	976|Bacteroidetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS2_k127_2424673_7	867902.Ornrh_0373	2.023e-95	328.0	COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
CMS2_k127_2436133_61	1168289.AJKI01000003_gene2872	1.283e-46	179.0	COG2374@1|root,COG2374@2|Bacteria,4NHFV@976|Bacteroidetes,2G2AH@200643|Bacteroidia,3XKMR@558415|Marinilabiliaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Exo_endo_phos
CMS2_k127_2436133_28	1237149.C900_03288	3.545e-122	398.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,47K20@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS2_k127_2436133_33	1237149.C900_03289	9.14e-105	346.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,47N59@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS2_k127_2436133_46	1279009.ADICEAN_01813	7.79e-82	278.0	COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes,47M5I@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_2436133_7	1124780.ANNU01000003_gene1417	1.086e-269	844.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS2_k127_2436133_75	1124780.ANNU01000003_gene1416	3.245e-21	94.0	2EGC0@1|root,33A3T@2|Bacteria,4NXPB@976|Bacteroidetes,47SUC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_24	1121859.KB890740_gene3855	2.801e-135	445.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_2436133_21	1191523.MROS_1169	1.719e-150	483.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_2436133_40	926549.KI421517_gene2451	1.831e-92	312.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,47JAX@768503|Cytophagia	976|Bacteroidetes	S	S1 P1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
CMS2_k127_2436133_70	1189612.A33Q_1767	4.66e-30	120.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,47R98@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS2_k127_2436133_42	1121904.ARBP01000001_gene5955	8.248e-88	295.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS2_k127_2436133_62	926556.Echvi_0024	9.524e-45	171.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CMS2_k127_2436133_4	313606.M23134_01651	1.654e-293	921.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,47JAK@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS2_k127_2436133_81	643867.Ftrac_2868	1.718e-08	59.0	2DSW7@1|root,33HNN@2|Bacteria,4NY8S@976|Bacteroidetes,47SU0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_76	153721.MYP_77	8.976e-20	92.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,47S0D@768503|Cytophagia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS2_k127_2436133_8	1237149.C900_04994	2.742e-268	832.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,47KJE@768503|Cytophagia	976|Bacteroidetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS2_k127_2436133_80	1356852.N008_04800	3.813e-09	67.0	2C2QD@1|root,32RAV@2|Bacteria,4NS64@976|Bacteroidetes,47V36@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_16	1237149.C900_03299	4.928e-186	592.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,47JMA@768503|Cytophagia	976|Bacteroidetes	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS2_k127_2436133_51	880070.Cycma_3108	2.148e-73	252.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,47JZQ@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	pabA	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS2_k127_2436133_22	1237149.C900_03301	2.342e-148	476.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,47KKR@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS2_k127_2436133_38	1237149.C900_03302	6.22e-97	323.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,47JRX@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS2_k127_2436133_58	649349.Lbys_2385	1.51e-55	201.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,47N69@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS2_k127_2436133_12	1237149.C900_03304	3.477e-208	651.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,47KSV@768503|Cytophagia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_2436133_36	1305737.JAFX01000001_gene190	2.417e-100	335.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,47JYN@768503|Cytophagia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS2_k127_2436133_19	1237149.C900_03306	4.438e-159	507.0	COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,47KY7@768503|Cytophagia	976|Bacteroidetes	E	PFAM DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS2_k127_2436133_83	1124780.ANNU01000060_gene928	1.766e-07	56.0	2DNXM@1|root,32ZP0@2|Bacteria,4NWRE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_78	714943.Mucpa_3182	6.051e-15	78.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CMS2_k127_2436133_71	485918.Cpin_1605	9.136e-30	121.0	2C4KB@1|root,32YM4@2|Bacteria,4NUZU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_63	143224.JQMD01000002_gene2486	3.971e-43	168.0	2CJWE@1|root,30Y1E@2|Bacteria,4NNQQ@976|Bacteroidetes,1I40A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_26	385682.AFSL01000008_gene2634	3.623e-128	427.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,2FMPU@200643|Bacteroidia,3XIZ1@558415|Marinilabiliaceae	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS2_k127_2436133_29	1237149.C900_00515	1.713e-117	390.0	COG0750@1|root,COG0750@2|Bacteria,4NI5C@976|Bacteroidetes,47K57@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS2_k127_2436133_48	1237149.C900_03623	1.917e-79	274.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
CMS2_k127_2436133_44	861299.J421_4144	3.304e-82	281.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS2_k127_2436133_30	1237149.C900_04765	3.027e-117	381.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,47P4U@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
CMS2_k127_2436133_10	1305737.JAFX01000001_gene339	6.188e-238	745.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47JC1@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_2436133_68	1237149.C900_00012	1.206e-33	137.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,47QK5@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
CMS2_k127_2436133_79	1237149.C900_00540	2.052e-14	79.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS2_k127_2436133_34	926556.Echvi_2128	2.842e-101	338.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47PIS@768503|Cytophagia	976|Bacteroidetes	M	Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS2_k127_2436133_5	1237149.C900_04420	3.029e-293	918.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4P15I@976|Bacteroidetes,47X8A@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_2436133_25	1237149.C900_01560	2.512e-130	428.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,47KMT@768503|Cytophagia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS2_k127_2436133_32	761193.Runsl_3978	5.249e-106	354.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47KCD@768503|Cytophagia	976|Bacteroidetes	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CMS2_k127_2436133_11	1237149.C900_03429	2.646e-230	729.0	COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,47Y2W@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Reg_prop,Response_reg
CMS2_k127_2436133_15	1237149.C900_03428	6.683e-202	636.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47NKU@768503|Cytophagia	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
CMS2_k127_2436133_59	1237149.C900_03426	1.491e-53	194.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R0S@768503|Cytophagia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_2436133_23	1121104.AQXH01000001_gene1691	4.405e-138	451.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS2_k127_2436133_39	926549.KI421517_gene3486	4.799e-96	325.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,47M1Q@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS2_k127_2436133_6	1237149.C900_03423	5.452e-277	885.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CMS2_k127_2436133_31	1237149.C900_03422	6.343e-111	378.0	COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,47JSU@768503|Cytophagia	976|Bacteroidetes	H	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
CMS2_k127_2436133_69	1237149.C900_03421	2.056e-30	132.0	COG3087@1|root,COG3087@2|Bacteria,4NVU5@976|Bacteroidetes,47S99@768503|Cytophagia	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_2436133_35	1237149.C900_03420	4.031e-101	333.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,47N0M@768503|Cytophagia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_2436133_65	643867.Ftrac_0328	6.391e-39	149.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,47R2X@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS2_k127_2436133_73	643867.Ftrac_0329	2.718e-25	116.0	COG3170@1|root,COG3170@2|Bacteria,4PKQP@976|Bacteroidetes,47JDN@768503|Cytophagia	976|Bacteroidetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_74	1191523.MROS_1594	6.168e-23	115.0	COG3537@1|root,COG3537@2|Bacteria	2|Bacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
CMS2_k127_2436133_20	760192.Halhy_3752	1.396e-152	503.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,1IW1W@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS2_k127_2436133_45	1237149.C900_01808	3.459e-82	282.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,47JXA@768503|Cytophagia	976|Bacteroidetes	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS2_k127_2436133_1	1237149.C900_01809	0.0	1158.0	COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,47YIP@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_2436133_41	1189612.A33Q_0663	4.947e-89	305.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS2_k127_2436133_43	153721.MYP_4849	1.744e-85	288.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_2436133_56	880070.Cycma_0483	1.464e-56	204.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS2_k127_2436133_9	1237149.C900_01813	3.175e-262	846.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
CMS2_k127_2436133_18	1237149.C900_01814	1.211e-163	523.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,47KQT@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_47	1123277.KB893184_gene3969	8.223e-81	284.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47JF1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS2_k127_2436133_53	655815.ZPR_2982	1.242e-62	223.0	COG0725@1|root,COG0725@2|Bacteria,4NMPV@976|Bacteroidetes,1I1B0@117743|Flavobacteriia	976|Bacteroidetes	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS2_k127_2436133_49	1317122.ATO12_05795	1.588e-78	268.0	COG4149@1|root,COG4149@2|Bacteria,4NIXK@976|Bacteroidetes,1I0Y9@117743|Flavobacteriia,2YH6W@290174|Aquimarina	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS2_k127_2436133_52	123214.PERMA_1915	7.357e-70	246.0	COG3842@1|root,COG3842@2|Bacteria,2G4NC@200783|Aquificae	200783|Aquificae	E	PFAM ABC transporter	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K15497	ko02010,map02010	M00189,M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5,3.A.1.8	-	-	ABC_tran
CMS2_k127_2436133_77	643867.Ftrac_3230	8.748e-16	89.0	COG3437@1|root,COG3437@2|Bacteria,4P4ET@976|Bacteroidetes,47V8E@768503|Cytophagia	976|Bacteroidetes	KT	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_3	1237149.C900_04077	2.193e-318	986.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,47JD4@768503|Cytophagia	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS2_k127_2436133_55	1121904.ARBP01000004_gene1083	1.402e-57	217.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47XNU@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS2_k127_2436133_27	1237149.C900_04080	7.205e-123	396.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,47N33@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS2_k127_2436133_17	1237149.C900_00286	7.371e-186	619.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
CMS2_k127_2436133_54	1237149.C900_02657	6.718e-58	204.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2436133_57	1237149.C900_02658	9.763e-56	202.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RJQ@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_2436133_50	1237149.C900_04849	2.007e-78	278.0	COG1572@1|root,COG1572@2|Bacteria,4NQCQ@976|Bacteroidetes,47QPX@768503|Cytophagia	976|Bacteroidetes	S	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS2_k127_2436133_14	1305737.JAFX01000001_gene3538	5.196e-204	643.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,47KAQ@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
CMS2_k127_2436133_67	1279009.ADICEAN_03895	1.142e-36	145.0	COG2032@1|root,COG2032@2|Bacteria	2|Bacteria	P	superoxide dismutase activity	sodC	-	1.15.1.1	ko:K02674,ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	-	-	-	Sod_Cu
CMS2_k127_2436133_2	1237149.C900_01185	0.0	1028.0	COG1629@1|root,COG1629@2|Bacteria,4PKRD@976|Bacteroidetes,47KHW@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_2436133_66	445961.IW15_02135	4.119e-38	148.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,3ZS40@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS2_k127_2436133_37	1237149.C900_03611	8.626e-100	342.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,PSCyt1,RNB,S1,WD40
CMS2_k127_2436133_13	1237149.C900_03612	3.722e-204	673.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,Peptidase_M43,VCBS,fn3
CMS2_k127_2436133_0	1237149.C900_03613	0.0	1680.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia	976|Bacteroidetes	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
CMS2_k127_24779_4	929703.KE386491_gene4224	9.347e-91	312.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,47N3H@768503|Cytophagia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_24779_8	700598.Niako_6250	3.209e-37	146.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_24779_1	1237149.C900_04398	2.437e-269	851.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,47ME6@768503|Cytophagia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS2_k127_24779_3	388413.ALPR1_17218	1.745e-239	750.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS2_k127_24779_6	313603.FB2170_11406	7.804e-73	251.0	COG3023@1|root,COG3023@2|Bacteria,4NMIV@976|Bacteroidetes,1HY6G@117743|Flavobacteriia,2PGH4@252356|Maribacter	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
CMS2_k127_24779_5	1237149.C900_05257	2.318e-90	306.0	29N3N@1|root,33SHJ@2|Bacteria,4P1XQ@976|Bacteroidetes,47TMQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_24779_0	1237149.C900_05256	0.0	1306.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
CMS2_k127_24779_7	1120968.AUBX01000010_gene886	4.8e-61	219.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia	976|Bacteroidetes	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS2_k127_24779_2	1237149.C900_05293	2.743e-244	775.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_251335_5	525373.HMPREF0766_10858	8.973e-51	186.0	COG0170@1|root,COG0170@2|Bacteria,4NNH3@976|Bacteroidetes,1IS9R@117747|Sphingobacteriia	976|Bacteroidetes	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182,2.7.7.41	ko:K00981,ko:K18678	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R10659	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS2_k127_251335_6	313606.M23134_05183	2.302e-06	55.0	2AFVR@1|root,315YE@2|Bacteria,4PK8B@976|Bacteroidetes,47SSJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_251335_4	1550091.JROE01000002_gene1149	3.255e-61	218.0	COG0170@1|root,COG0170@2|Bacteria,4NNH3@976|Bacteroidetes,1IS9R@117747|Sphingobacteriia	976|Bacteroidetes	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182,2.7.7.41	ko:K00981,ko:K18678	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R10659	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS2_k127_251335_3	714943.Mucpa_6223	2.272e-135	439.0	COG5379@1|root,COG5379@2|Bacteria,4NIGH@976|Bacteroidetes,1J0CP@117747|Sphingobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
CMS2_k127_251335_0	1550091.JROE01000002_gene1151	0.0	1049.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,4NH4R@976|Bacteroidetes,1ISB2@117747|Sphingobacteriia	976|Bacteroidetes	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS2_k127_251335_2	1550091.JROE01000002_gene1152	3.405e-139	449.0	COG0382@1|root,COG0382@2|Bacteria,4NKPE@976|Bacteroidetes,1IW35@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_251335_1	153721.MYP_4591	1.58e-196	620.0	COG1257@1|root,COG1257@2|Bacteria,4NGN1@976|Bacteroidetes,47NJ8@768503|Cytophagia	976|Bacteroidetes	I	hydroxymethylglutaryl-CoA reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
CMS2_k127_2534036_4	1217703.F904_02974	3.934e-05	52.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,3NJV2@468|Moraxellaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,RHS,RHS_repeat
CMS2_k127_2534036_0	406818.XBJ1_1302	3.708e-33	131.0	COG1396@1|root,COG1396@2|Bacteria,1R044@1224|Proteobacteria,1S8G2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_2534036_2	330214.NIDE1715	7.772e-21	108.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat,VCBS
CMS2_k127_2550501_1	643867.Ftrac_0603	1.357e-190	619.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
CMS2_k127_2550501_3	643867.Ftrac_0604	2.771e-68	243.0	COG1596@1|root,COG1596@2|Bacteria,4NFXJ@976|Bacteroidetes,47R1R@768503|Cytophagia	976|Bacteroidetes	M	PFAM Polysaccharide biosynthesis export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
CMS2_k127_2550501_6	388413.ALPR1_09895	2.797e-25	109.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP,DegT_DnrJ_EryC1
CMS2_k127_2550501_0	391596.PBAL39_05243	9.223e-196	616.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,1IQAV@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS2_k127_2550501_5	1250006.JHZZ01000001_gene1416	4.034e-31	126.0	2DMPS@1|root,32SXU@2|Bacteria,4NTIT@976|Bacteroidetes,1I41A@117743|Flavobacteriia,3VXF5@52959|Polaribacter	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS2_k127_2550501_2	929556.Solca_4166	8.992e-147	471.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1IQ44@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS2_k127_2550501_4	335541.Swol_0701	1.279e-60	214.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	HTH_20,HTH_5,NTP_transf_2
CMS2_k127_2605241_0	1237149.C900_02057	9.799e-179	563.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,47MPT@768503|Cytophagia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_2605241_1	1121875.KB907548_gene1538	6.156e-162	517.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1HYFP@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS2_k127_2660506_2	760192.Halhy_5862	4.273e-65	247.0	COG4783@1|root,COG4783@2|Bacteria,4NM0X@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS2_k127_2660506_6	1123277.KB893217_gene4475	3.431e-05	51.0	2FB64@1|root,343CE@2|Bacteria,4P5E5@976|Bacteroidetes,47VYW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2660506_5	1443665.JACA01000014_gene4445	2.456e-20	95.0	2E4J8@1|root,32ZEA@2|Bacteria,4NW6Q@976|Bacteroidetes,1I69T@117743|Flavobacteriia,2YJEK@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2541
CMS2_k127_2660506_4	1392489.JPOL01000002_gene1620	1.67e-58	207.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1I17D@117743|Flavobacteriia,2XK0P@283735|Leeuwenhoekiella	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.17.2.1	ko:K18029	ko00760,ko01120,map00760,map01120	M00622	R09473	RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_2660506_0	655815.ZPR_2974	4.817e-251	794.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HZR9@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS2_k127_2660506_3	1229487.AMYW01000021_gene1731	4.961e-59	219.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZ3N@117743|Flavobacteriia,2NXGC@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_2660506_1	1121012.AUKX01000021_gene1700	1.576e-65	228.0	COG0664@1|root,COG0664@2|Bacteria,4PMAC@976|Bacteroidetes,1HXBX@117743|Flavobacteriia,23HR3@178469|Arenibacter	976|Bacteroidetes	T	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS2_k127_279405_8	1286632.P278_32200	8.553e-213	668.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
CMS2_k127_279405_12	1237149.C900_04351	7.372e-176	561.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,47JUJ@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme, glucanotransferase domain	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
CMS2_k127_279405_1	1237149.C900_04352	0.0	1028.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
CMS2_k127_279405_19	1237149.C900_02568	4.177e-132	430.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MGC@768503|Cytophagia	976|Bacteroidetes	K	PFAM Periplasmic binding protein LacI transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CMS2_k127_279405_28	641524.ADICYQ_0472	4.042e-47	171.0	COG4226@1|root,COG4226@2|Bacteria,4NSCC@976|Bacteroidetes,47SF5@768503|Cytophagia	976|Bacteroidetes	S	PFAM HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
CMS2_k127_279405_32	880070.Cycma_4487	1.654e-29	119.0	2E9T0@1|root,333Z2@2|Bacteria,4NUQI@976|Bacteroidetes,47SUM@768503|Cytophagia	976|Bacteroidetes	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS2_k127_279405_10	1237149.C900_01388	2.606e-196	626.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MR6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Alpha amylase, catalytic	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,BACON,DUF3459
CMS2_k127_279405_14	1296416.JACB01000051_gene2692	2.482e-156	500.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,1HZ07@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M19	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS2_k127_279405_29	1392489.JPOL01000002_gene835	6.127e-44	164.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1I1KB@117743|Flavobacteriia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS2_k127_279405_15	926559.JoomaDRAFT_1637	2.554e-151	490.0	COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,1HY9I@117743|Flavobacteriia	976|Bacteroidetes	EG	H gluconate symporter and related	gntT	-	-	ko:K06155	-	-	-	-	ko00000,ko02000	2.A.8.1.4	-	-	GntP_permease
CMS2_k127_279405_33	1173028.ANKO01000195_gene5993	7.769e-29	129.0	COG0642@1|root,COG2205@2|Bacteria,1G0TS@1117|Cyanobacteria,1H8JZ@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS2_k127_279405_26	877455.Metbo_0326	3.831e-63	235.0	COG0642@1|root,COG0784@1|root,COG3920@1|root,arCOG02335@2157|Archaea,arCOG06192@2157|Archaea,arCOG06537@2157|Archaea,2Y3ED@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,Response_reg
CMS2_k127_279405_13	1237149.C900_03281	2.845e-162	552.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,47YNN@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_279405_2	1237149.C900_03280	6.193e-293	940.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,47JEP@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_279405_36	1279009.ADICEAN_01818	3.351e-20	94.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,47R4M@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS2_k127_279405_37	1237149.C900_03278	2.748e-19	89.0	2E3I4@1|root,32YGK@2|Bacteria,4NUQ9@976|Bacteroidetes,47S6Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_279405_27	1197477.IA57_03060	1.601e-59	210.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
CMS2_k127_279405_38	1121904.ARBP01000004_gene950	8.603e-08	61.0	COG1999@1|root,COG1999@2|Bacteria,4NY1A@976|Bacteroidetes,47W0K@768503|Cytophagia	976|Bacteroidetes	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_279405_6	1237149.C900_05850	1.68e-226	708.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,47K1B@768503|Cytophagia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
CMS2_k127_279405_22	761193.Runsl_1018	6.943e-96	322.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,47JDA@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_279405_4	1237149.C900_00279	6.76e-239	751.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,47K91@768503|Cytophagia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS2_k127_279405_11	643867.Ftrac_0148	1.585e-177	559.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,47M06@768503|Cytophagia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS2_k127_279405_3	1237149.C900_00272	3.471e-246	765.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,47JRV@768503|Cytophagia	976|Bacteroidetes	E	PFAM Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS2_k127_279405_23	1408473.JHXO01000007_gene965	2.439e-92	314.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,2FNX3@200643|Bacteroidia	976|Bacteroidetes	S	Bile acid	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS2_k127_279405_31	391587.KAOT1_13997	2.769e-34	141.0	COG3279@1|root,COG3279@2|Bacteria,4NF8A@976|Bacteroidetes,1HZ0Z@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS2_k127_279405_35	504487.JCM19302_2219	1.291e-23	117.0	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_10,TPR_12,TPR_7,TPR_8,Y_Y_Y
CMS2_k127_279405_5	929562.Emtol_3540	2.462e-238	766.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47MAT@768503|Cytophagia	976|Bacteroidetes	CG	Cytochrome c, class I	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA
CMS2_k127_279405_21	521097.Coch_1306	5.858e-97	329.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZK0@117743|Flavobacteriia,1EQBM@1016|Capnocytophaga	976|Bacteroidetes	K	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_279405_7	1408473.JHXO01000003_gene2552	9.045e-225	720.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,2FNUV@200643|Bacteroidia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_279405_24	1121396.KB893077_gene743	1.377e-85	301.0	COG1228@1|root,COG3629@1|root,COG1228@2|Bacteria,COG3629@2|Bacteria,1Q0HP@1224|Proteobacteria,42URV@68525|delta/epsilon subdivisions,2WQQ1@28221|Deltaproteobacteria,2MPRD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_279405_9	485918.Cpin_5677	7.899e-205	641.0	COG3239@1|root,COG3239@2|Bacteria	2|Bacteria	I	unsaturated fatty acid biosynthetic process	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_279405_18	153721.MYP_2938	7.023e-135	438.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47TX7@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_279405_0	760192.Halhy_0750	0.0	1161.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,1IQJ2@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	cbgA_1	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS2_k127_279405_34	1122226.AUHX01000045_gene2582	1.294e-28	119.0	COG3093@1|root,COG3093@2|Bacteria,4NZ9K@976|Bacteroidetes	976|Bacteroidetes	K	addiction module antidote protein HigA	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_279405_25	626887.J057_16860	1.808e-63	228.0	COG3366@1|root,COG3366@2|Bacteria,1P2FE@1224|Proteobacteria,1RRXD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM nucleoside recognition domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_279405_30	431947.PGN_0754	1.545e-39	153.0	COG0791@1|root,COG0791@2|Bacteria,4NUNS@976|Bacteroidetes,2G39E@200643|Bacteroidia,231MB@171551|Porphyromonadaceae	976|Bacteroidetes	M	P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
CMS2_k127_279405_16	1121912.AUHD01000008_gene55	1.153e-150	490.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_279405_39	1124780.ANNU01000016_gene1861	2.617e-07	59.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_279405_20	760192.Halhy_1186	1.718e-125	415.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IVTA@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	3.5.1.32	ko:K01436,ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_279405_17	700598.Niako_6550	1.391e-137	445.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1IQIA@117747|Sphingobacteriia	976|Bacteroidetes	C	potassium channel beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_2936906_6	1042376.AFPK01000010_gene510	5.712e-19	86.0	2EG32@1|root,339V1@2|Bacteria,4NXHK@976|Bacteroidetes,1I69U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2936906_7	1121875.KB907549_gene2057	1.963e-06	51.0	2932B@1|root,2ZQJH@2|Bacteria,4P6ZB@976|Bacteroidetes,1IBVV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2936906_5	313606.M23134_04697	5.413e-27	119.0	COG3103@1|root,COG3103@2|Bacteria,4NIH7@976|Bacteroidetes,47P4Z@768503|Cytophagia	976|Bacteroidetes	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4
CMS2_k127_2936906_8	421531.IX38_17190	1.05e-05	53.0	COG4886@1|root,COG4886@2|Bacteria,4PKYN@976|Bacteroidetes,1IJHN@117743|Flavobacteriia,3ZUN3@59732|Chryseobacterium	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2936906_0	1237149.C900_03990	4.634e-243	757.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,47JG8@768503|Cytophagia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS2_k127_2936906_1	1237149.C900_03991	1.417e-237	742.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,47KC2@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS2_k127_2936906_4	643867.Ftrac_3606	1.86e-30	129.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2936906_3	1124780.ANNU01000054_gene3519	4.084e-109	358.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,47JJ9@768503|Cytophagia	976|Bacteroidetes	I	enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS2_k127_2936906_2	153721.MYP_4888	1.965e-132	433.0	COG0643@1|root,COG0643@2|Bacteria,4NG31@976|Bacteroidetes,47MM7@768503|Cytophagia	976|Bacteroidetes	NT	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS2_k127_30078_0	1249997.JHZW01000002_gene1571	6.071e-26	107.0	COG3344@1|root,COG3344@2|Bacteria,4NHMS@976|Bacteroidetes,1HZPH@117743|Flavobacteriia	976|Bacteroidetes	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
CMS2_k127_30078_1	1540257.JQMW01000011_gene1492	1.607e-23	113.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,36H7U@31979|Clostridiaceae	186801|Clostridia	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
CMS2_k127_3141025_0	1122176.KB903532_gene2517	0.0	1533.0	COG3383@1|root,COG3383@2|Bacteria,4PKV4@976|Bacteroidetes,1IX2V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	hndD	-	1.12.1.3,1.17.1.9	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS2_k127_3141025_2	859653.HIMB5_00002640	5.803e-182	584.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,4BPQM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Respiratory-chain NADH dehydrogenase 51 Kd subunit	fdsB	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS2_k127_3141025_7	1317122.ATO12_01120	3.221e-114	374.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,1I19N@117743|Flavobacteriia,2YI2A@290174|Aquimarina	976|Bacteroidetes	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS2_k127_3141025_1	1120965.AUBV01000010_gene2738	0.0	1079.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS2_k127_3141025_12	1237149.C900_01197	1.102e-49	182.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
CMS2_k127_3141025_13	761193.Runsl_4613	1.176e-26	114.0	COG0346@1|root,COG0346@2|Bacteria,4NTXG@976|Bacteroidetes,47R2Z@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_3141025_14	929703.KE386491_gene2893	2.788e-13	75.0	2C5P8@1|root,32U6D@2|Bacteria,4NSY7@976|Bacteroidetes,47R86@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3141025_11	153721.MYP_531	1.124e-59	226.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,47JRE@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
CMS2_k127_3141025_8	1237149.C900_04751	8.174e-103	341.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,47JBK@768503|Cytophagia	976|Bacteroidetes	S	Zn-ribbon protein, possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS2_k127_3141025_3	1121904.ARBP01000009_gene4217	7.601e-142	458.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,47JGH@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS2_k127_3141025_9	313606.M23134_05187	4.067e-89	305.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,47M44@768503|Cytophagia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS2_k127_3141025_6	1237149.C900_04748	3.464e-115	394.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,47JRI@768503|Cytophagia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
CMS2_k127_3141025_10	1237149.C900_04747	2.176e-78	267.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,47P6J@768503|Cytophagia	976|Bacteroidetes	FJ	Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CMS2_k127_3141025_4	1168289.AJKI01000002_gene2576	4.542e-122	400.0	COG0457@1|root,COG0457@2|Bacteria	1168289.AJKI01000002_gene2576|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3141025_5	153721.MYP_3706	1.586e-115	389.0	2C5KB@1|root,2ZCDW@2|Bacteria,4NMNY@976|Bacteroidetes,47PDN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3202488_29	573413.Spirs_1160	5.534e-32	130.0	COG0454@1|root,COG0456@2|Bacteria,2JB1N@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_3202488_9	1121904.ARBP01000004_gene1065	9.435e-154	500.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS2_k127_3202488_1	641524.ADICYQ_0052	1.111e-222	701.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47N97@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_3202488_11	1408813.AYMG01000010_gene540	6.791e-130	421.0	COG2234@1|root,COG2234@2|Bacteria,4NIQX@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS2_k127_3202488_20	518766.Rmar_2484	8.996e-88	299.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes	976|Bacteroidetes	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS2_k127_3202488_15	694427.Palpr_0725	1.146e-114	375.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,2FSSJ@200643|Bacteroidia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS2_k127_3202488_10	1120965.AUBV01000013_gene1337	2.245e-153	493.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_3202488_32	1237149.C900_02689	3.018e-24	102.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,47RX4@768503|Cytophagia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_3202488_12	880071.Fleli_1085	1.073e-129	420.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_3202488_3	216432.CA2559_05285	7.836e-193	608.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWZU@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the thiolase family	pcaF	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS2_k127_3202488_4	1120966.AUBU01000005_gene3813	4.14e-174	557.0	COG1228@1|root,COG1228@2|Bacteria,4P0JM@976|Bacteroidetes	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_3202488_8	1123248.KB893328_gene922	1.668e-157	504.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IW53@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_3202488_25	1237149.C900_00046	1.15e-56	202.0	COG5502@1|root,COG5502@2|Bacteria,4NN8N@976|Bacteroidetes,47W5C@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
CMS2_k127_3202488_34	595460.RRSWK_02061	1.113e-11	70.0	2EPJ9@1|root,33H5X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
CMS2_k127_3202488_2	688270.Celal_2938	3.589e-215	697.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS2_k127_3202488_13	1506583.JQJY01000008_gene3877	1.06e-120	397.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,1IIR4@117743|Flavobacteriia,2P03I@237|Flavobacterium	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS2_k127_3202488_0	1450525.JATV01000013_gene2927	1.754e-250	794.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,1I00H@117743|Flavobacteriia,2NV1D@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS2_k127_3202488_22	1396858.Q666_05615	2.412e-68	250.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
CMS2_k127_3202488_19	1408433.JHXV01000031_gene3257	7.061e-91	323.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia,2PB04@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
CMS2_k127_3202488_16	1279009.ADICEAN_03647	1.804e-107	359.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
CMS2_k127_3202488_31	1250232.JQNJ01000001_gene239	1.835e-24	110.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS2_k127_3202488_24	1288963.ADIS_4503	6.547e-60	214.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,47NYB@768503|Cytophagia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
CMS2_k127_3202488_28	1237149.C900_00045	5.01e-42	160.0	COG0645@1|root,COG0645@2|Bacteria,4NSKU@976|Bacteroidetes,47RG0@768503|Cytophagia	976|Bacteroidetes	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS2_k127_3202488_17	700598.Niako_2305	4.168e-98	331.0	COG2187@1|root,COG2187@2|Bacteria,4NKD3@976|Bacteroidetes,1IXH4@117747|Sphingobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
CMS2_k127_3202488_18	362418.IW19_15940	1.123e-92	308.0	COG3145@1|root,COG3145@2|Bacteria,4NFEG@976|Bacteroidetes,1HWRD@117743|Flavobacteriia,2NSMD@237|Flavobacterium	976|Bacteroidetes	L	2OG-Fe(II) oxygenase	alkB	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
CMS2_k127_3202488_33	926556.Echvi_3034	1.672e-23	101.0	COG4895@1|root,COG4895@2|Bacteria,4NUT0@976|Bacteroidetes,47RYA@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
CMS2_k127_3202488_26	1249975.JQLP01000005_gene2417	2.406e-55	201.0	COG3931@1|root,COG3931@2|Bacteria,4NMA3@976|Bacteroidetes,1I1FX@117743|Flavobacteriia,2P6RV@244698|Gillisia	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS2_k127_3202488_7	1237149.C900_03855	1.983e-159	512.0	COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes	976|Bacteroidetes	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
CMS2_k127_3202488_5	1237149.C900_03854	1.898e-172	554.0	COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,47P1C@768503|Cytophagia	976|Bacteroidetes	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
CMS2_k127_3202488_21	1237149.C900_03853	1.083e-76	264.0	COG3271@1|root,COG3271@2|Bacteria,4NN8E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
CMS2_k127_3202488_23	1237149.C900_03852	3.279e-68	236.0	COG1595@1|root,COG1595@2|Bacteria,4NNP4@976|Bacteroidetes,47P6Z@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_3202488_30	1223410.KN050846_gene2837	5.109e-25	105.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
CMS2_k127_3202488_14	1123248.KB893352_gene1783	1.118e-119	413.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
CMS2_k127_3202488_27	468059.AUHA01000006_gene3011	5.278e-52	187.0	COG0745@1|root,COG0745@2|Bacteria,4NQ69@976|Bacteroidetes,1ISWK@117747|Sphingobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_3202488_6	925409.KI911562_gene2742	2.178e-165	525.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1IPZU@117747|Sphingobacteriia	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
CMS2_k127_3229990_1	1237149.C900_03482	9.65e-279	866.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,47JVG@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS2_k127_3229990_8	1237149.C900_03483	4.794e-84	287.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,47KUM@768503|Cytophagia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS2_k127_3229990_16	926556.Echvi_3448	3.634e-41	157.0	COG1413@1|root,COG1413@2|Bacteria,4NPKR@976|Bacteroidetes,47PWP@768503|Cytophagia	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS2_k127_3229990_2	1237149.C900_03749	1.064e-220	706.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_3229990_10	153721.MYP_242	6.82e-71	244.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,47P6H@768503|Cytophagia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS2_k127_3229990_15	1124780.ANNU01000049_gene2219	9.769e-47	173.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,47PWR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3229990_3	1237149.C900_03862	2.618e-206	648.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,47JM9@768503|Cytophagia	976|Bacteroidetes	L	PFAM MgsA AAA ATPase C terminal	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS2_k127_3229990_14	1120968.AUBX01000018_gene2060	9.785e-54	196.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,47P9D@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
CMS2_k127_3229990_17	1250006.JHZZ01000001_gene2191	1.374e-36	147.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,3VW6J@52959|Polaribacter	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_3229990_6	1237149.C900_05494	8.821e-122	405.0	COG0477@1|root,COG2814@2|Bacteria,4NE7F@976|Bacteroidetes,47MD0@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS2_k127_3229990_7	1237149.C900_02106	2.885e-107	356.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,47JRS@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS2_k127_3229990_4	1237149.C900_04522	2.391e-149	483.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47M71@768503|Cytophagia	976|Bacteroidetes	T	Signal transduction histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS2_k127_3229990_9	1237149.C900_04521	1.974e-72	251.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,47PED@768503|Cytophagia	976|Bacteroidetes	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_3229990_5	1237149.C900_01734	7.243e-132	433.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,47MCP@768503|Cytophagia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_3229990_0	1121904.ARBP01000005_gene4592	9.983e-280	876.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,47KDI@768503|Cytophagia	976|Bacteroidetes	G	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
CMS2_k127_3229990_12	1239962.C943_00479	9.941e-56	211.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Collagen,Gln_amidase,OMP_b-brl_2
CMS2_k127_3229990_11	1237149.C900_03262	3.088e-64	235.0	COG3468@1|root,COG3468@2|Bacteria,4NEVR@976|Bacteroidetes	976|Bacteroidetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_3242154_41	1237149.C900_05519	3.505e-59	211.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_3242154_64	1042163.BRLA_c040610	3.743e-13	73.0	2EAD0@1|root,334GW@2|Bacteria,1VIU9@1239|Firmicutes,4HXYA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3242154_17	1237149.C900_00002	4.091e-155	496.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,47JPY@768503|Cytophagia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS2_k127_3242154_24	929703.KE386491_gene3267	1.582e-130	424.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,47K8J@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CMS2_k127_3242154_43	1237149.C900_03339	2.043e-53	194.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,47RBP@768503|Cytophagia	976|Bacteroidetes	I	PFAM PAP2 superfamily	ybjG	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS2_k127_3242154_21	1237149.C900_03342	3.143e-139	447.0	COG0408@1|root,COG0408@2|Bacteria,4NFZS@976|Bacteroidetes,47M0F@768503|Cytophagia	976|Bacteroidetes	H	PFAM coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS2_k127_3242154_2	1124780.ANNU01000032_gene1240	2.443e-305	949.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47JUS@768503|Cytophagia	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS2_k127_3242154_35	1237149.C900_05652	9.538e-77	259.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,47PUA@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS2_k127_3242154_15	1237149.C900_00938	3.552e-166	542.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,47JZB@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_3242154_30	1237149.C900_00937	5.578e-97	320.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,47MHB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS2_k127_3242154_26	1237149.C900_00936	1.546e-112	368.0	COG4783@1|root,COG4783@2|Bacteria,4PKN7@976|Bacteroidetes,47YC0@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS2_k127_3242154_23	755732.Fluta_2801	1.481e-135	436.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1HWQX@117743|Flavobacteriia,2PA8X@246874|Cryomorphaceae	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS2_k127_3242154_51	866536.Belba_2928	4.407e-35	139.0	COG1393@1|root,COG1393@2|Bacteria,4NXD1@976|Bacteroidetes,47SWP@768503|Cytophagia	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS2_k127_3242154_13	1237149.C900_01566	2.469e-184	587.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Sodium alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS2_k127_3242154_19	1237149.C900_01568	8.959e-148	475.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS2_k127_3242154_28	643867.Ftrac_0120	9.497e-108	354.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,47N5P@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS2_k127_3242154_18	153721.MYP_622	4.219e-153	495.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,47JEX@768503|Cytophagia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_3242154_6	1237149.C900_05140	1.773e-242	757.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS2_k127_3242154_61	269798.CHU_1358	2.251e-16	83.0	COG3063@1|root,COG3063@2|Bacteria,4PKQM@976|Bacteroidetes,47XZ3@768503|Cytophagia	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS2_k127_3242154_29	1120966.AUBU01000010_gene2759	4.185e-106	348.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,47KZ2@768503|Cytophagia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS2_k127_3242154_27	1120965.AUBV01000013_gene1285	4.484e-112	370.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,47JUQ@768503|Cytophagia	976|Bacteroidetes	C	Electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS2_k127_3242154_36	1237149.C900_05134	3.243e-74	254.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,47KJI@768503|Cytophagia	976|Bacteroidetes	L	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
CMS2_k127_3242154_5	1237149.C900_05130	1.051e-259	809.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,47JC3@768503|Cytophagia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS2_k127_3242154_10	1121875.KB907547_gene3019	2.887e-190	608.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS2_k127_3242154_31	1121904.ARBP01000038_gene2567	3.195e-96	324.0	COG1940@1|root,COG1940@2|Bacteria,4NHNJ@976|Bacteroidetes	976|Bacteroidetes	GK	rok family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS2_k127_3242154_34	1121904.ARBP01000038_gene2568	5.158e-85	295.0	COG0738@1|root,COG0738@2|Bacteria,4NHZ7@976|Bacteroidetes	976|Bacteroidetes	G	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS2_k127_3242154_25	742727.HMPREF9447_04166	4.044e-120	389.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,2FMFV@200643|Bacteroidia,4AQCC@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
CMS2_k127_3242154_3	1237149.C900_05125	2.676e-284	880.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,47JYW@768503|Cytophagia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS2_k127_3242154_46	1237149.C900_05124	3.199e-45	164.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS2_k127_3242154_49	1124780.ANNU01000023_gene3189	2.927e-39	156.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3242154_56	1237149.C900_05122	3.857e-26	111.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,47SC6@768503|Cytophagia	976|Bacteroidetes	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS2_k127_3242154_53	1237149.C900_05121	1.057e-29	131.0	2ECXC@1|root,336UI@2|Bacteria,4NV8T@976|Bacteroidetes,47RWP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3242154_50	1120966.AUBU01000002_gene2280	9.594e-38	148.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,47P8C@768503|Cytophagia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
CMS2_k127_3242154_12	1237149.C900_05119	7.989e-187	591.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,47JXW@768503|Cytophagia	976|Bacteroidetes	K	sigma54 specific, transcriptional regulator, Fis family	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS2_k127_3242154_7	1239962.C943_02999	3.957e-236	737.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,47MGS@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS2_k127_3242154_37	1189612.A33Q_2850	1.286e-69	239.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,47PIB@768503|Cytophagia	976|Bacteroidetes	S	carbonic anhydrase acetyltransferase	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS2_k127_3242154_47	643867.Ftrac_0745	2.369e-42	164.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R3F@768503|Cytophagia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_3242154_48	643867.Ftrac_0744	5.084e-42	161.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,47MRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS2_k127_3242154_0	1237149.C900_05108	0.0	1076.0	COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia	976|Bacteroidetes	C	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
CMS2_k127_3242154_1	1237149.C900_05107	0.0	1050.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes,47NKP@768503|Cytophagia	976|Bacteroidetes	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS2_k127_3242154_52	1121373.KB903632_gene414	8.793e-34	144.0	2E0MA@1|root,32W6I@2|Bacteria,4NNWD@976|Bacteroidetes,47Q2K@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_3242154_42	1237149.C900_05105	7.488e-54	204.0	COG1520@1|root,COG1520@2|Bacteria,4NEVC@976|Bacteroidetes,47KRP@768503|Cytophagia	976|Bacteroidetes	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3242154_44	1121897.AUGO01000013_gene3168	1.034e-49	206.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS2_k127_3242154_4	1237149.C900_03432	1.89e-265	893.0	COG3291@1|root,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia	976|Bacteroidetes	Q	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PKD
CMS2_k127_3242154_8	1237149.C900_00597	2.501e-231	748.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,47MQP@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3242154_9	1120966.AUBU01000001_gene1209	5.897e-223	703.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_3242154_33	1237149.C900_00595	1.013e-86	289.0	COG5405@1|root,COG5405@2|Bacteria,4NHZ8@976|Bacteroidetes,47MJS@768503|Cytophagia	976|Bacteroidetes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS2_k127_3242154_54	865938.Weevi_2053	7.992e-29	119.0	COG1393@1|root,COG1393@2|Bacteria,4NSA6@976|Bacteroidetes,1I40J@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS2_k127_3242154_32	1120965.AUBV01000007_gene2490	2.669e-88	301.0	COG0111@1|root,COG0111@2|Bacteria,4NE9J@976|Bacteroidetes,47JBD@768503|Cytophagia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
CMS2_k127_3242154_20	1237149.C900_00782	6.834e-147	471.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,47MQ3@768503|Cytophagia	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
CMS2_k127_3242154_38	714943.Mucpa_2582	5.483e-68	241.0	COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,1IWF7@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS2_k127_3242154_11	1168289.AJKI01000014_gene2087	1.278e-188	633.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,2G0D6@200643|Bacteroidia,3XIMN@558415|Marinilabiliaceae	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48,FlgD_ig
CMS2_k127_3242154_57	1123368.AUIS01000035_gene81	3.435e-24	109.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
CMS2_k127_3242154_63	984262.SGRA_3025	1.003e-15	80.0	COG0393@1|root,COG0393@2|Bacteria,4PK34@976|Bacteroidetes,1IUME@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CMS2_k127_3242154_66	1347393.HG726027_gene2267	3.911e-10	67.0	29F7N@1|root,3025B@2|Bacteria,4NNR8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS2_k127_3242154_16	1519464.HY22_06245	4.645e-163	529.0	COG2268@1|root,COG2268@2|Bacteria	2|Bacteria	T	Band 7 protein	yqiK	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
CMS2_k127_3242154_55	1237149.C900_00240	1.805e-26	111.0	COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS2_k127_3242154_39	1237149.C900_05758	7.185e-63	220.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3242154_59	1237149.C900_05757	1.765e-23	105.0	COG3339@1|root,COG3339@2|Bacteria,4NVFR@976|Bacteroidetes,47RD8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS2_k127_3242154_40	388413.ALPR1_03970	2.061e-61	213.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,47PUX@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS2_k127_3242154_22	269798.CHU_2702	3.382e-137	441.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,47JU5@768503|Cytophagia	976|Bacteroidetes	D	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS2_k127_3242154_14	1121875.KB907550_gene657	4.234e-180	573.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_3242154_60	1122605.KB893647_gene321	6.801e-23	105.0	28H8Z@1|root,30SVU@2|Bacteria,4NY56@976|Bacteroidetes	976|Bacteroidetes	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS2_k127_3242154_62	555779.Dthio_PD0622	2.991e-16	86.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,42UXZ@68525|delta/epsilon subdivisions,2WR0B@28221|Deltaproteobacteria,2MAZ1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	CheC, inhibitor of MCP methylation	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
CMS2_k127_3242154_58	632292.Calhy_0597	1.291e-23	104.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,42GI7@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS2_k127_3242154_45	1131812.JQMS01000001_gene1974	3.944e-48	190.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia,2P01I@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
CMS2_k127_3242154_65	344747.PM8797T_15426	2.545e-12	78.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
CMS2_k127_3264761_25	153721.MYP_3486	6.547e-05	45.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS2_k127_3264761_14	1237149.C900_01005	3.87e-53	205.0	COG0810@1|root,COG0810@2|Bacteria,4NSYT@976|Bacteroidetes,47W0H@768503|Cytophagia	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_C
CMS2_k127_3264761_13	1237149.C900_01006	2.003e-56	202.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,47P9F@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_3264761_2	1237149.C900_01007	3.354e-256	803.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
CMS2_k127_3264761_6	1237149.C900_01001	9.259e-115	381.0	COG2972@1|root,COG2972@2|Bacteria,4NIER@976|Bacteroidetes,47P26@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
CMS2_k127_3264761_8	1237149.C900_01002	1.441e-102	338.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,47KUT@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_3264761_1	1237149.C900_01004	3.151e-266	829.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47UI6@768503|Cytophagia	976|Bacteroidetes	U	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS2_k127_3264761_20	504487.JCM19302_4171	8.239e-22	104.0	2AZZ1@1|root,31S92@2|Bacteria,4NR5H@976|Bacteroidetes,1I0PY@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_3264761_4	761193.Runsl_3481	1.042e-161	537.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
CMS2_k127_3264761_15	1239962.C943_01704	1.375e-46	180.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
CMS2_k127_3264761_11	926549.KI421517_gene1934	5.579e-66	235.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3264761_19	1492737.FEM08_16910	3.298e-30	126.0	COG4083@1|root,COG4083@2|Bacteria,4NM52@976|Bacteroidetes,1I1BK@117743|Flavobacteriia,2NWGW@237|Flavobacterium	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	groEL	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS2_k127_3264761_17	880070.Cycma_0696	6.078e-37	145.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,47S81@768503|Cytophagia	976|Bacteroidetes	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
CMS2_k127_3264761_10	1124780.ANNU01000006_gene2896	3.591e-67	238.0	COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,47QA7@768503|Cytophagia	976|Bacteroidetes	S	Glucose-regulated metallo-peptidase M90	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
CMS2_k127_3264761_12	1237149.C900_04744	1.036e-58	213.0	29UMW@1|root,32RE0@2|Bacteria,4NPAH@976|Bacteroidetes,47PRV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3264761_0	1121904.ARBP01000009_gene4340	0.0	1037.0	COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4PNA4@976|Bacteroidetes,47YAQ@768503|Cytophagia	976|Bacteroidetes	CG	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
CMS2_k127_3264761_7	616991.JPOO01000003_gene203	1.746e-107	357.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1HY1C@117743|Flavobacteriia,23FT6@178469|Arenibacter	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_3264761_24	1443122.Z958_03065	2.222e-05	56.0	COG4932@1|root,COG4932@2|Bacteria,1V3NP@1239|Firmicutes,24J6W@186801|Clostridia,36IXS@31979|Clostridiaceae	186801|Clostridia	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS2_k127_3264761_26	335543.Sfum_0444	0.0004374	52.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria,42VJ7@68525|delta/epsilon subdivisions,2WS0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
CMS2_k127_3264761_23	1168034.FH5T_16970	2.72e-11	68.0	COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
CMS2_k127_3264761_9	1123057.P872_21265	3.706e-68	241.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47UNC@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3264761_5	1121875.KB907546_gene2674	9.907e-119	389.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,1I01K@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
CMS2_k127_3264761_3	866536.Belba_1302	5.711e-182	578.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS2_k127_3264761_16	866536.Belba_1301	2.065e-39	158.0	2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3264761_18	929556.Solca_2236	8.615e-34	134.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_3264761_21	1237149.C900_01451	8.414e-21	95.0	COG1943@1|root,COG1943@2|Bacteria,4NJZI@976|Bacteroidetes,47PW0@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_3265710_3	1123248.KB893325_gene1171	0.0	1068.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NHVG@976|Bacteroidetes,1IQPM@117747|Sphingobacteriia	976|Bacteroidetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
CMS2_k127_3265710_19	1121904.ARBP01000006_gene3852	5.625e-134	433.0	COG0726@1|root,COG0726@2|Bacteria,4NKYS@976|Bacteroidetes,47NF6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	pgdA	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS2_k127_3265710_8	616991.JPOO01000003_gene1612	8.28e-233	730.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,23HR7@178469|Arenibacter	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS2_k127_3265710_32	313603.FB2170_09296	5.802e-114	372.0	COG2133@1|root,COG2133@2|Bacteria,4NIMV@976|Bacteroidetes,1I02Z@117743|Flavobacteriia,2PGSP@252356|Maribacter	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_3265710_17	700598.Niako_4079	2.099e-140	449.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
CMS2_k127_3265710_62	1123248.KB893315_gene3111	1.509e-39	150.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1IYKS@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS2_k127_3265710_7	1122176.KB903598_gene4618	1.609e-239	752.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS2_k127_3265710_45	1111728.ATYS01000023_gene3991	7.197e-79	267.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.3.1.28	ko:K03271,ko:K12961	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005,ko03036	-	-	-	SIS_2
CMS2_k127_3265710_10	1237149.C900_03964	4.409e-216	687.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS2_k127_3265710_13	1237149.C900_03963	6.415e-169	547.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47JNN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
CMS2_k127_3265710_64	1237149.C900_03962	4.679e-38	144.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,47R60@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS2_k127_3265710_18	1189612.A33Q_0745	2.13e-136	444.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,47XWC@768503|Cytophagia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
CMS2_k127_3265710_37	1237149.C900_03960	1.058e-101	344.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,47XWD@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III, delta' subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
CMS2_k127_3265710_36	866536.Belba_0315	4.977e-103	343.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,47M9Y@768503|Cytophagia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
CMS2_k127_3265710_44	1237149.C900_03958	3.445e-82	281.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS2_k127_3265710_31	929703.KE386491_gene2277	3.761e-114	375.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,47MQV@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS2_k127_3265710_69	1197477.IA57_10625	5.699e-06	56.0	2CIHR@1|root,332YQ@2|Bacteria,4NVAM@976|Bacteroidetes,1I60E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3265710_23	1237149.C900_03873	1.195e-123	403.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,47KA8@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM YihY family protein (not ribonuclease BN)	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS2_k127_3265710_56	1237149.C900_03872	1.945e-52	188.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS2_k127_3265710_21	1237149.C900_03871	5.72e-132	429.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,47J93@768503|Cytophagia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS2_k127_3265710_58	1237149.C900_05499	1.67e-51	189.0	COG0349@1|root,COG0349@2|Bacteria,4NP3B@976|Bacteroidetes,47QFS@768503|Cytophagia	976|Bacteroidetes	J	3'-5' exonuclease	rnd	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
CMS2_k127_3265710_11	1237149.C900_05500	3.024e-201	637.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,47KKY@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM Na H antiporter NhaC	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
CMS2_k127_3265710_20	1121904.ARBP01000005_gene4880	5.235e-132	430.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS2_k127_3265710_30	1237149.C900_04589	2.165e-114	377.0	COG0226@1|root,COG0226@2|Bacteria,4NKND@976|Bacteroidetes,47PVA@768503|Cytophagia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_3265710_12	1237149.C900_04590	2.583e-170	541.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,47KHB@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_3265710_24	1237149.C900_04591	1.14e-119	389.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,47MA3@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3265710_35	1237149.C900_04592	4.061e-107	365.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
CMS2_k127_3265710_57	1237149.C900_04593	1.024e-51	194.0	2C97B@1|root,2ZAEJ@2|Bacteria,4NEK0@976|Bacteroidetes,47MC2@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility associated protien GldN	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3265710_9	1237149.C900_04594	2.746e-232	733.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,47JXP@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS2_k127_3265710_4	1237149.C900_04595	8.848e-300	937.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia	976|Bacteroidetes	M	Penicillin binding protein transpeptidase	pbpB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS2_k127_3265710_6	1237149.C900_04596	1.837e-254	811.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,47K0V@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeats	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
CMS2_k127_3265710_41	643867.Ftrac_2563	6.503e-88	298.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,47PPP@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_3265710_54	1237149.C900_04598	6.315e-53	189.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47RT9@768503|Cytophagia	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS2_k127_3265710_70	1121957.ATVL01000010_gene422	4.849e-05	48.0	2EFZ5@1|root,339RB@2|Bacteria,4NXH9@976|Bacteroidetes	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
CMS2_k127_3265710_33	1124780.ANNU01000006_gene2927	5.019e-112	370.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,47JYV@768503|Cytophagia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS2_k127_3265710_67	1288963.ADIS_2189	1.054e-22	99.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,47S5V@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS2_k127_3265710_60	1120966.AUBU01000008_gene2473	5.301e-46	171.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,47Q9K@768503|Cytophagia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS2_k127_3265710_61	866536.Belba_0654	8.376e-45	168.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS2_k127_3265710_5	1237149.C900_04605	1.22e-282	874.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,47JFI@768503|Cytophagia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS2_k127_3265710_25	1237149.C900_04606	3.945e-118	386.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,47JM0@768503|Cytophagia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS2_k127_3265710_50	1237149.C900_03498	5.426e-62	233.0	COG2885@1|root,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_3265710_51	1121859.KB890741_gene3772	9.437e-62	216.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,47P8B@768503|Cytophagia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS2_k127_3265710_59	1122971.BAME01000016_gene1900	1.542e-47	172.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,2FT28@200643|Bacteroidia,22Y6R@171551|Porphyromonadaceae	976|Bacteroidetes	S	MazG nucleotide pyrophosphohydrolase domain	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS2_k127_3265710_55	880071.Fleli_1077	7.731e-53	198.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,47Q2F@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
CMS2_k127_3265710_49	1237149.C900_03791	4.444e-63	218.0	COG2199@1|root,COG3706@2|Bacteria,4PKDN@976|Bacteroidetes,47QRP@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_3265710_15	1237149.C900_03789	2.624e-157	515.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS2_k127_3265710_42	1237149.C900_03788	2.725e-83	281.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
CMS2_k127_3265710_14	1124780.ANNU01000075_gene834	4.122e-162	519.0	COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,47JFQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS2_k127_3265710_40	1237149.C900_03785	2.974e-91	308.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,47K9N@768503|Cytophagia	976|Bacteroidetes	F	PFAM Phosphorylase superfamily	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS2_k127_3265710_46	1123057.P872_05800	1.057e-71	248.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,47PJQ@768503|Cytophagia	976|Bacteroidetes	S	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS2_k127_3265710_52	1237149.C900_03783	3.508e-56	212.0	28ICP@1|root,32QUE@2|Bacteria,4NR8Q@976|Bacteroidetes,47QZP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3265710_29	1237149.C900_03782	1.54e-114	383.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,47KPJ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
CMS2_k127_3265710_28	643867.Ftrac_2671	1.026e-115	379.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,47JHC@768503|Cytophagia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS2_k127_3265710_47	1237149.C900_03780	1.561e-69	241.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,47PRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
CMS2_k127_3265710_2	1237149.C900_03779	0.0	1084.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,47JI0@768503|Cytophagia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS2_k127_3265710_22	1189612.A33Q_0424	6.859e-130	424.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS2_k127_3265710_16	1121904.ARBP01000019_gene2813	7.706e-147	475.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia	976|Bacteroidetes	H	MoeZ MoeB domain	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CMS2_k127_3265710_38	760192.Halhy_5630	2.959e-99	334.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS2_k127_3265710_66	1121904.ARBP01000006_gene3726	1.59e-23	102.0	COG1977@1|root,COG1977@2|Bacteria,4NVP9@976|Bacteroidetes,47VNX@768503|Cytophagia	976|Bacteroidetes	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
CMS2_k127_3265710_27	1121904.ARBP01000006_gene3725	6.429e-117	387.0	COG4447@1|root,COG4447@2|Bacteria,4NKUX@976|Bacteroidetes,47U4I@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3265710_34	700598.Niako_5160	5.199e-109	359.0	COG1319@1|root,COG1319@2|Bacteria,4NFT8@976|Bacteroidetes,1IV94@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS2_k127_3265710_48	1382356.JQMP01000004_gene227	2.843e-66	229.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_3265710_1	700598.Niako_5158	0.0	1409.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,1IVK4@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS2_k127_3265710_53	700598.Niako_5157	1.396e-53	195.0	COG3427@1|root,COG3427@2|Bacteria,4NRMQ@976|Bacteroidetes	2|Bacteria	S	PFAM Carbon monoxide dehydrogenase subunit G (CoxG)	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS2_k127_3265710_26	760192.Halhy_5288	7.68e-118	385.0	COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes,1IW28@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ATPase associated with various cellular activities AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS2_k127_3265710_39	700598.Niako_5155	6.559e-98	332.0	COG3552@1|root,COG3552@2|Bacteria,4NK40@976|Bacteroidetes,1IWRV@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS2_k127_3265710_43	700598.Niako_5154	1.326e-82	285.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,4NP35@976|Bacteroidetes,1IVW7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
CMS2_k127_3265710_0	616991.JPOO01000001_gene2737	0.0	1526.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6B@976|Bacteroidetes,1HZB8@117743|Flavobacteriia,23H5B@178469|Arenibacter	976|Bacteroidetes	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
CMS2_k127_3265710_63	236814.IX39_10740	1.826e-39	154.0	2E4Y6@1|root,32ZS3@2|Bacteria,4NWH0@976|Bacteroidetes,1I50G@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082
CMS2_k127_326936_1	1237149.C900_04328	1.129e-141	453.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS2_k127_326936_4	1120965.AUBV01000004_gene799	6.128e-27	121.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,47SGM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_326936_0	761193.Runsl_0539	1.369e-277	885.0	COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4NKVN@976|Bacteroidetes,47MDT@768503|Cytophagia	976|Bacteroidetes	CG	Carbohydrate binding module (family 6)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
CMS2_k127_326936_2	1120965.AUBV01000005_gene1718	2.113e-121	399.0	COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,47KMQ@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS2_k127_326936_3	290512.Paes_2156	1.47e-61	219.0	COG5587@1|root,COG5587@2|Bacteria,1FEPB@1090|Chlorobi	1090|Chlorobi	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
CMS2_k127_3292304_5	1121007.AUML01000028_gene2105	6.989e-59	218.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	MORN,Peptidase_M48
CMS2_k127_3292304_8	869213.JCM21142_72631	7.274e-37	141.0	COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS2_k127_3292304_0	1168289.AJKI01000001_gene3661	3.414e-206	648.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,2FNEC@200643|Bacteroidia,3XJJF@558415|Marinilabiliaceae	976|Bacteroidetes	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS2_k127_3292304_7	1120965.AUBV01000001_gene3167	1.208e-44	179.0	COG1404@1|root,COG1404@2|Bacteria,4NI53@976|Bacteroidetes,47MBD@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8	-	-	3.4.21.62	ko:K01342	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8
CMS2_k127_3292304_6	1123057.P872_08630	9.865e-56	222.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47QEI@768503|Cytophagia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_17,TPR_8
CMS2_k127_3292304_2	1288963.ADIS_2438	1.104e-151	490.0	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,47KTV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
CMS2_k127_3292304_1	1120966.AUBU01000005_gene3591	1.06e-189	602.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes	976|Bacteroidetes	O	COG NOG08360 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS2_k127_3292304_4	1237149.C900_04995	3.068e-114	389.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NJKM@976|Bacteroidetes,47NZZ@768503|Cytophagia	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
CMS2_k127_3292304_3	1178825.ALIH01000011_gene1	5.055e-145	462.0	COG1230@1|root,COG1230@2|Bacteria,4NGFR@976|Bacteroidetes,1HWS2@117743|Flavobacteriia	976|Bacteroidetes	P	cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
CMS2_k127_3292304_12	1121904.ARBP01000035_gene1747	3.189e-08	58.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
CMS2_k127_3292304_9	153721.MYP_1231	3.431e-24	104.0	2A9A6@1|root,30YF4@2|Bacteria,4PC8F@976|Bacteroidetes,47WYN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3333998_1	1120965.AUBV01000012_gene1394	6.157e-08	55.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
CMS2_k127_3333998_0	1120965.AUBV01000006_gene2153	8.43e-189	601.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47N92@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_3343933_7	693979.Bache_0526	1.696e-10	69.0	COG3595@1|root,COG3595@2|Bacteria,4NX4P@976|Bacteroidetes,2G3DB@200643|Bacteroidia,4AWDV@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG16223 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_3343933_4	643867.Ftrac_1115	1.049e-48	189.0	2FI0F@1|root,3433Q@2|Bacteria,4P46Y@976|Bacteroidetes,47VJN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3343933_2	313606.M23134_08314	2.08e-54	197.0	COG1595@1|root,COG1595@2|Bacteria,4NU4K@976|Bacteroidetes,47UQA@768503|Cytophagia	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_3343933_1	1237149.C900_05603	4.855e-114	372.0	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,47K6K@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS2_k127_3343933_5	1517682.HW49_09705	1.6e-18	93.0	2F1S9@1|root,33USE@2|Bacteria,4P2N2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3343933_3	1237149.C900_00614	2.175e-51	184.0	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,47QB4@768503|Cytophagia	976|Bacteroidetes	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
CMS2_k127_3343933_0	1237149.C900_00616	1.615e-151	484.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47M49@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS2_k127_3343933_6	1168289.AJKI01000008_gene694	3.495e-11	65.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,3XJGG@558415|Marinilabiliaceae	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS2_k127_3363_3	1434325.AZQN01000004_gene1852	1.836e-128	415.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,47KEK@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
CMS2_k127_3363_8	1121481.AUAS01000012_gene376	2.625e-65	229.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,47PVC@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS2_k127_3363_6	1237149.C900_00199	4.19e-103	346.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,47JDC@768503|Cytophagia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS2_k127_3363_1	1237149.C900_00196	1.184e-218	683.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,47JDR@768503|Cytophagia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS2_k127_3363_5	1237149.C900_00195	1.258e-108	355.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,47K60@768503|Cytophagia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS2_k127_3363_4	1237149.C900_00194	8.43e-127	419.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,47KTD@768503|Cytophagia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
CMS2_k127_3363_0	1237149.C900_00193	0.0	1086.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,47JQ8@768503|Cytophagia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS2_k127_3363_7	1237149.C900_00192	8.295e-84	280.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,47P99@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS2_k127_3363_9	1120968.AUBX01000014_gene2251	5.449e-24	105.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes,47R73@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS2_k127_3363_2	1237149.C900_00190	1.732e-187	593.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,47JQ0@768503|Cytophagia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS2_k127_3390369_1	1237149.C900_04390	6.398e-220	689.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS2_k127_3390369_3	929562.Emtol_2016	1.665e-131	430.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,47M8R@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS2_k127_3390369_6	926549.KI421517_gene1967	1.506e-36	145.0	COG0746@1|root,COG0746@2|Bacteria,4NMYW@976|Bacteroidetes,47NQP@768503|Cytophagia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS2_k127_3390369_4	319236.JCM19294_1389	4.515e-99	333.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1HX0R@117743|Flavobacteriia,3HK1Y@363408|Nonlabens	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS2_k127_3390369_2	926559.JoomaDRAFT_2831	1.832e-134	434.0	COG1834@1|root,COG1834@2|Bacteria,4NEUJ@976|Bacteroidetes,1HWNG@117743|Flavobacteriia	976|Bacteroidetes	E	Cytochrome C biogenesis protein CcmF	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS2_k127_3390369_0	867900.Celly_2987	0.0	1253.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia,1F9VX@104264|Cellulophaga	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_3390369_7	1123057.P872_05155	1.196e-32	130.0	COG2314@1|root,COG2314@2|Bacteria,4NWIC@976|Bacteroidetes,47PUE@768503|Cytophagia	976|Bacteroidetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
CMS2_k127_3390369_8	869213.JCM21142_93917	3.246e-26	110.0	2EBA7@1|root,335AR@2|Bacteria,4NYHP@976|Bacteroidetes,47X50@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
CMS2_k127_3390369_5	362418.IW19_18160	4.616e-40	155.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,1I0Q1@117743|Flavobacteriia,2NS8W@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_3415_7	643867.Ftrac_2583	4.304e-19	100.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NQHU@976|Bacteroidetes,47R06@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
CMS2_k127_3415_2	1237149.C900_04937	3.27e-85	291.0	COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,47MFN@768503|Cytophagia	976|Bacteroidetes	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Phytase-like
CMS2_k127_3415_1	1189612.A33Q_4528	2.352e-120	396.0	COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,47NUW@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS2_k127_3415_3	1121904.ARBP01000006_gene4064	1.353e-83	299.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47JI8@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
CMS2_k127_3415_8	1237149.C900_04942	2.503e-18	85.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,47RUZ@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS2_k127_3415_6	1124780.ANNU01000090_gene319	4.237e-19	91.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,47S3A@768503|Cytophagia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS2_k127_3415_0	1237149.C900_04944	6.543e-200	636.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS2_k127_3415_5	1279009.ADICEAN_03511	1.847e-48	181.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,47NST@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS2_k127_3415_4	929556.Solca_4297	3.882e-56	200.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1IS0K@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
CMS2_k127_3440461_0	1239962.C943_03674	1.295e-229	756.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47KSH@768503|Cytophagia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,CarbopepD_reg_2,Plug
CMS2_k127_3440461_3	985255.APHJ01000019_gene522	6.975e-14	78.0	297G1@1|root,2ZUPC@2|Bacteria,4P908@976|Bacteroidetes,1IBQ8@117743|Flavobacteriia,2P7KC@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3440461_2	1267535.KB906767_gene2182	2.743e-85	291.0	COG0657@1|root,COG0657@2|Bacteria,3Y2TC@57723|Acidobacteria,2JIM8@204432|Acidobacteriia	204432|Acidobacteriia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS2_k127_3440461_1	1123035.ARLA01000007_gene630	6.758e-170	543.0	COG0249@1|root,COG0249@2|Bacteria,4NGEA@976|Bacteroidetes,1HYPR@117743|Flavobacteriia	976|Bacteroidetes	L	MutS domain V	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
CMS2_k127_3454723_2	1237149.C900_04554	0.0	1124.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,47JE2@768503|Cytophagia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS2_k127_3454723_9	762903.Pedsa_0190	7.07e-61	218.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1IS2Z@117747|Sphingobacteriia	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CMS2_k127_3454723_3	926551.KB900719_gene291	1.246e-204	646.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1HZYU@117743|Flavobacteriia,1ER0M@1016|Capnocytophaga	976|Bacteroidetes	G	F5 8 type C domain protein	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
CMS2_k127_3454723_12	1317122.ATO12_00115	0.0001823	50.0	2BU8Y@1|root,32PIF@2|Bacteria,4PAKP@976|Bacteroidetes,1ICHN@117743|Flavobacteriia,2YM2X@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3454723_10	1408473.JHXO01000005_gene1471	3.687e-33	135.0	COG1309@1|root,COG1309@2|Bacteria,4NW3D@976|Bacteroidetes	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_3454723_8	313606.M23134_01615	4.601e-89	301.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,47SW9@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS2_k127_3454723_4	1313421.JHBV01000042_gene3353	8.358e-112	374.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_3454723_5	1313421.JHBV01000042_gene3354	5.836e-103	348.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1IVIT@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_3454723_6	313606.M23134_01607	8.406e-103	338.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,47TWR@768503|Cytophagia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_3454723_7	1121904.ARBP01000002_gene6765	1.472e-92	317.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3454723_0	1121875.KB907547_gene3382	0.0	1521.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS2_k127_3454723_1	1122176.KB903537_gene1704	0.0	1410.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IR3P@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS2_k127_3454723_11	643867.Ftrac_1661	7.322e-14	73.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
CMS2_k127_3457442_0	1250005.PHEL85_0702	0.0	1139.0	COG0438@1|root,COG4632@1|root,COG0438@2|Bacteria,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes,1I6BU@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,fn3
CMS2_k127_3493191_7	313606.M23134_06196	2.251e-37	144.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_3493191_6	1279009.ADICEAN_01507	2.872e-61	217.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_3493191_2	616991.JPOO01000003_gene2342	1.884e-227	719.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,1HZ2A@117743|Flavobacteriia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3493191_9	926549.KI421517_gene1208	9.443e-30	126.0	COG2867@1|root,COG2867@2|Bacteria,4NNHS@976|Bacteroidetes,47P7J@768503|Cytophagia	976|Bacteroidetes	I	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
CMS2_k127_3493191_8	1406840.Q763_15635	2.201e-30	124.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS2_k127_3493191_5	616991.JPOO01000003_gene2489	6.2e-122	405.0	COG2610@1|root,COG2610@2|Bacteria,4NFQH@976|Bacteroidetes,1I149@117743|Flavobacteriia,23IHZ@178469|Arenibacter	976|Bacteroidetes	EG	GntP family permease	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
CMS2_k127_3493191_3	1250232.JQNJ01000001_gene473	4.054e-177	566.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,1HZG2@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_3493191_0	866536.Belba_3185	4.439e-297	930.0	COG1960@1|root,COG1960@2|Bacteria,4NF87@976|Bacteroidetes,47NXN@768503|Cytophagia	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.3.6	ko:K00232	ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146	M00087,M00113	R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_3493191_4	1237149.C900_01159	2.459e-126	410.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,47K35@768503|Cytophagia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS2_k127_3493191_1	643867.Ftrac_0852	4.58e-272	846.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,47MYG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS2_k127_3493191_10	9361.ENSDNOP00000019515	4.749e-11	69.0	COG0326@1|root,KOG0019@2759|Eukaryota,3996F@33154|Opisthokonta,3CDCC@33208|Metazoa,3DU0Z@33213|Bilateria,48H4P@7711|Chordata,49E1F@7742|Vertebrata	33208|Metazoa	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3514070_3	926549.KI421517_gene2398	1.207e-115	380.0	COG1082@1|root,COG1082@2|Bacteria,4NKJV@976|Bacteroidetes,47PJ1@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_3514070_0	616991.JPOO01000003_gene1581	1.252e-243	754.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1I5PN@117743|Flavobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_3514070_2	616991.JPOO01000003_gene1582	6.807e-129	417.0	COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_3514070_5	504472.Slin_2646	3.405e-77	268.0	COG1940@1|root,COG1940@2|Bacteria,4NH8S@976|Bacteroidetes,47J9G@768503|Cytophagia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS2_k127_3514070_4	616991.JPOO01000003_gene1583	1.338e-112	366.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes	976|Bacteroidetes	S	protein containing SIS (Sugar ISomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
CMS2_k127_3514070_6	1392498.JQLH01000001_gene3340	3.207e-35	136.0	COG1476@1|root,COG1476@2|Bacteria,4NRXY@976|Bacteroidetes,1IKAV@117743|Flavobacteriia	976|Bacteroidetes	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_3514070_1	688270.Celal_0409	5.738e-183	581.0	COG3550@1|root,COG3550@2|Bacteria,4NFYY@976|Bacteroidetes,1HXAI@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
CMS2_k127_3515889_46	1237149.C900_04582	3.667e-16	78.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_3515889_6	1237149.C900_01718	3.868e-217	683.0	COG1055@1|root,COG1055@2|Bacteria,4NGWD@976|Bacteroidetes,47KPC@768503|Cytophagia	976|Bacteroidetes	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
CMS2_k127_3515889_12	1237149.C900_04908	1.316e-177	564.0	COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes,47KWD@768503|Cytophagia	976|Bacteroidetes	E	Glu Leu Phe Val dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_3515889_11	1237149.C900_04029	1.14e-177	559.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,47MD1@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS2_k127_3515889_36	1120965.AUBV01000003_gene599	2.721e-47	175.0	COG0664@1|root,COG0664@2|Bacteria,4NQ89@976|Bacteroidetes,47QJZ@768503|Cytophagia	976|Bacteroidetes	T	PFAM Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS2_k127_3515889_27	929562.Emtol_0815	8.021e-90	312.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
CMS2_k127_3515889_17	1237149.C900_04026	2.563e-137	453.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,47KAE@768503|Cytophagia	976|Bacteroidetes	M	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
CMS2_k127_3515889_32	1237149.C900_04025	2.418e-68	239.0	2AEI8@1|root,331SH@2|Bacteria,4NWWM@976|Bacteroidetes,47S6K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3515889_28	1237149.C900_04024	1.964e-89	302.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS2_k127_3515889_38	761193.Runsl_4244	9.912e-39	147.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,47RC2@768503|Cytophagia	976|Bacteroidetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
CMS2_k127_3515889_15	1237149.C900_04022	1.481e-158	509.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,47MHR@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS2_k127_3515889_20	1237149.C900_04021	2.631e-110	364.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,47N7V@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
CMS2_k127_3515889_33	1453498.LG45_03400	6.633e-67	235.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1I1UF@117743|Flavobacteriia,2NVBJ@237|Flavobacterium	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3515889_39	865937.Gilli_0865	5.938e-38	144.0	COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,1I3VH@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
CMS2_k127_3515889_19	1237149.C900_00776	1.079e-120	401.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,47NWS@768503|Cytophagia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
CMS2_k127_3515889_21	1237149.C900_05070	8.946e-108	363.0	2CF5E@1|root,2ZFJ4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS2_k127_3515889_35	1279009.ADICEAN_01038	2.644e-51	190.0	2BXI0@1|root,2Z9A2@2|Bacteria,4NFDQ@976|Bacteroidetes,47QAC@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
CMS2_k127_3515889_2	1250278.JQNQ01000001_gene3177	3.964e-311	975.0	COG3934@1|root,COG3934@2|Bacteria,4NFVS@976|Bacteroidetes,1HZVW@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS2_k127_3515889_7	1121875.KB907549_gene2024	2.524e-214	676.0	COG2303@1|root,COG2303@2|Bacteria,4NMEP@976|Bacteroidetes,1IA7R@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
CMS2_k127_3515889_43	643867.Ftrac_3408	3.284e-23	108.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
CMS2_k127_3515889_14	1392498.JQLH01000001_gene2924	2.731e-168	538.0	COG0624@1|root,COG0624@2|Bacteria,4NJN0@976|Bacteroidetes,1I0Y3@117743|Flavobacteriia,2PI95@252356|Maribacter	976|Bacteroidetes	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_3515889_40	1121481.AUAS01000018_gene442	7.249e-36	140.0	COG3304@1|root,COG3304@2|Bacteria,4NQSS@976|Bacteroidetes,47RAQ@768503|Cytophagia	976|Bacteroidetes	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
CMS2_k127_3515889_13	1121904.ARBP01000001_gene5647	2.296e-177	559.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS2_k127_3515889_4	1519464.HY22_03410	5.769e-243	764.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1FDT3@1090|Chlorobi	1090|Chlorobi	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS2_k127_3515889_25	1237149.C900_00736	1.069e-101	337.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,47NAG@768503|Cytophagia	976|Bacteroidetes	J	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS2_k127_3515889_5	391587.KAOT1_07188	1.97e-224	720.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein related to penicillin acylase	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS2_k127_3515889_0	1237149.C900_00735	0.0	1355.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12
CMS2_k127_3515889_3	1305737.JAFX01000001_gene116	2.444e-306	972.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,47JW5@768503|Cytophagia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS2_k127_3515889_10	1227739.Hsw_3184	2.111e-184	587.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,47KR6@768503|Cytophagia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS2_k127_3515889_9	1313301.AUGC01000014_gene2457	2.309e-187	591.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS2_k127_3515889_18	1237149.C900_03678	8.781e-132	429.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,47JHT@768503|Cytophagia	976|Bacteroidetes	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS2_k127_3515889_24	1123057.P872_06725	3.854e-104	346.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,47JNH@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_3515889_41	517418.Ctha_0665	4.303e-35	141.0	COG0671@1|root,COG0671@2|Bacteria,1FFPS@1090|Chlorobi	1090|Chlorobi	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS2_k127_3515889_34	1121904.ARBP01000013_gene420	2.006e-66	248.0	COG0840@1|root,COG0840@2|Bacteria,4NIJR@976|Bacteroidetes,47XEI@768503|Cytophagia	976|Bacteroidetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,HAMP,MCPsignal
CMS2_k127_3515889_29	643867.Ftrac_0316	4.705e-83	283.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS2_k127_3515889_16	1237149.C900_03682	3.202e-142	457.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,47KZ9@768503|Cytophagia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_3515889_30	1434325.AZQN01000003_gene2268	9.379e-76	262.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47MMI@768503|Cytophagia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CMS2_k127_3515889_23	1237149.C900_03685	7.993e-106	368.0	COG5002@1|root,COG5002@2|Bacteria,4PKMH@976|Bacteroidetes,47XWJ@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_9,TPR_12
CMS2_k127_3515889_1	1237149.C900_03692	0.0	1005.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,47JRN@768503|Cytophagia	976|Bacteroidetes	F	PFAM Glutamine amidotransferase, class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7
CMS2_k127_3515889_31	1121904.ARBP01000010_gene2401	5.313e-71	253.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,47RSW@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS2_k127_3515889_44	1250006.JHZZ01000001_gene1660	4.008e-18	98.0	2EZ38@1|root,33S9G@2|Bacteria,4P0FQ@976|Bacteroidetes,1I8CU@117743|Flavobacteriia,3VWYX@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3515889_8	1042376.AFPK01000038_gene582	5.996e-202	642.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HYXG@117743|Flavobacteriia	976|Bacteroidetes	GM	Glycosyl transferase family 21	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_hydro_26,Glyco_hydro_2_C,Glyco_transf_21
CMS2_k127_3515889_26	1042376.AFPK01000038_gene578	1.698e-100	339.0	COG4124@1|root,COG4124@2|Bacteria,4PPF2@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
CMS2_k127_3515889_37	1408433.JHXV01000001_gene883	3.773e-44	168.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1I24A@117743|Flavobacteriia,2PBZM@246874|Cryomorphaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_3515889_22	1218173.BALCAV_0201095	7.877e-107	351.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,1ZCUB@1386|Bacillus	91061|Bacilli	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
CMS2_k127_3515889_45	592029.DDD_1268	4.269e-18	100.0	COG2885@1|root,COG2885@2|Bacteria,4NECX@976|Bacteroidetes,1HZVB@117743|Flavobacteriia	976|Bacteroidetes	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS2_k127_3536849_10	761193.Runsl_2560	1.391e-133	430.0	COG3828@1|root,COG3828@2|Bacteria,4PNCT@976|Bacteroidetes,47NTF@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS2_k127_3536849_3	761193.Runsl_2557	1.244e-223	700.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_3536849_13	509635.N824_15670	1.138e-105	357.0	COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,1IR1M@117747|Sphingobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS2_k127_3536849_8	1550091.JROE01000005_gene2105	3.788e-161	520.0	COG0673@1|root,COG0673@2|Bacteria,4NG5T@976|Bacteroidetes,1IRR9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Oxidoreduct_C
CMS2_k127_3536849_2	643867.Ftrac_1245	6.851e-272	863.0	COG4206@1|root,COG4206@2|Bacteria,4PKFW@976|Bacteroidetes,47Y2Y@768503|Cytophagia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
CMS2_k127_3536849_18	1121904.ARBP01000006_gene3739	2.242e-59	218.0	COG2972@1|root,COG2972@2|Bacteria,4NK1H@976|Bacteroidetes,47M46@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS2_k127_3536849_17	1121904.ARBP01000006_gene3738	9.876e-67	234.0	COG3279@1|root,COG3279@2|Bacteria,4NNIK@976|Bacteroidetes,47XE1@768503|Cytophagia	976|Bacteroidetes	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS2_k127_3536849_9	643867.Ftrac_0489	5.137e-157	505.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M80@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS2_k127_3536849_19	45351.EDO25595	2.71e-56	201.0	COG0386@1|root,KOG1651@2759|Eukaryota,3A1XE@33154|Opisthokonta,3BJ9B@33208|Metazoa	33208|Metazoa	O	glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CMS2_k127_3536849_14	1121104.AQXH01000001_gene984	5.001e-79	277.0	COG0665@1|root,COG0665@2|Bacteria,4NKQK@976|Bacteroidetes,1IWYI@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS2_k127_3536849_6	929703.KE386491_gene540	1.055e-175	574.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47N2K@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS2_k127_3536849_16	504472.Slin_5426	3.295e-71	243.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47XN3@768503|Cytophagia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_3536849_15	760192.Halhy_0717	4.616e-75	254.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1IWSE@117747|Sphingobacteriia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_3536849_0	1121875.KB907549_gene1727	0.0	1121.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_3536849_5	1237149.C900_03457	1.32e-179	571.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,47NB9@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_3536849_1	1237149.C900_03353	3.1e-276	856.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,47J97@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_3536849_11	1469557.JSWF01000033_gene1651	1.075e-122	404.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1HYD2@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS2_k127_3536849_7	1123234.AUKI01000023_gene1972	2.71e-170	545.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
CMS2_k127_3536849_4	1122176.KB903533_gene2443	1.239e-218	685.0	COG0673@1|root,COG0673@2|Bacteria,4NIF1@976|Bacteroidetes,1IVYW@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_3536849_20	1243664.CAVL020000019_gene3673	2.971e-43	170.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HCSH@91061|Bacilli,1ZCZY@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_3536849_12	1121904.ARBP01000009_gene4293	7.109e-112	367.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,47JFN@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_3536849_23	1123278.KB893522_gene2493	7.093e-05	47.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS2_k127_3546084_0	388413.ALPR1_18083	0.0	1486.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_3546084_15	1430440.MGMSRv2_2832	2.154e-09	68.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,2UA53@28211|Alphaproteobacteria,2JWXG@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_3546084_8	929562.Emtol_4153	2.511e-95	325.0	28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,47NT0@768503|Cytophagia	976|Bacteroidetes	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
CMS2_k127_3546084_11	700598.Niako_6499	4.093e-43	161.0	2C85M@1|root,31482@2|Bacteria,4NS0C@976|Bacteroidetes,1IYQ0@117747|Sphingobacteriia	976|Bacteroidetes	S	Stress responsive alpha-beta barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS2_k127_3546084_4	1121904.ARBP01000004_gene1108	4.993e-241	769.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_3546084_2	1237149.C900_03907	0.0	1061.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_3546084_9	596152.DesU5LDRAFT_2752	4.239e-47	186.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M7RA@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
CMS2_k127_3546084_13	1121904.ARBP01000008_gene3384	4.915e-38	159.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,4P2BP@976|Bacteroidetes	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_3546084_10	376686.Fjoh_2938	8.112e-45	171.0	COG0526@1|root,COG0526@2|Bacteria,4NPJ9@976|Bacteroidetes,1ICU2@117743|Flavobacteriia,2NUT1@237|Flavobacterium	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_2
CMS2_k127_3546084_5	1237149.C900_04830	2.462e-171	539.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,47JYS@768503|Cytophagia	976|Bacteroidetes	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS2_k127_3546084_3	761193.Runsl_2417	3.369e-277	869.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
CMS2_k127_3546084_14	504472.Slin_1748	1.471e-23	108.0	COG0500@1|root,COG2226@2|Bacteria,4NSPB@976|Bacteroidetes,47RD0@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_2,Methyltransf_25
CMS2_k127_3546084_12	1237149.C900_02050	9.47e-43	165.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHB@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_3546084_6	1121875.KB907550_gene664	1.196e-111	372.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
CMS2_k127_3546084_1	376686.Fjoh_4193	0.0	1174.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,2P0MK@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS2_k127_3546084_7	1121904.ARBP01000002_gene7112	2.321e-97	326.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JHW@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_3552277_56	1237149.C900_02074	7.519e-13	73.0	COG3411@1|root,COG3411@2|Bacteria,4P8H1@976|Bacteroidetes,47WRY@768503|Cytophagia	976|Bacteroidetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
CMS2_k127_3552277_13	1124780.ANNU01000019_gene1782	3.78e-162	519.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS2_k127_3552277_24	743722.Sph21_3382	3.122e-111	369.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS2_k127_3552277_47	866536.Belba_3559	3.731e-30	124.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,47RT6@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS2_k127_3552277_20	869213.JCM21142_41638	3.317e-124	409.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,47KXG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_3552277_29	926549.KI421517_gene3536	1.588e-90	306.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,47N0Z@768503|Cytophagia	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS2_k127_3552277_27	1237149.C900_00774	7.054e-93	321.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575,OmpA,PD40
CMS2_k127_3552277_34	1237149.C900_00773	3.098e-70	270.0	COG3209@1|root,COG3291@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	espK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07004,ko:K18491,ko:K20276	ko02024,ko04550,map02024,map04550	-	-	-	ko00000,ko00001,ko03000	-	-	-	CHU_C,CarboxypepD_reg,PKD
CMS2_k127_3552277_17	1250005.PHEL85_1913	1.135e-137	444.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1HYEZ@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS2_k127_3552277_10	1121904.ARBP01000003_gene6593	2.371e-196	624.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,47K1J@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS2_k127_3552277_31	1121904.ARBP01000004_gene928	1.669e-86	302.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,47NVA@768503|Cytophagia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS2_k127_3552277_37	1237149.C900_00826	3.379e-58	207.0	2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_10
CMS2_k127_3552277_36	1286632.P278_28410	5.479e-66	239.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1I0Q4@117743|Flavobacteriia	976|Bacteroidetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
CMS2_k127_3552277_46	1237149.C900_03507	9.999e-39	147.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,47RC7@768503|Cytophagia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS2_k127_3552277_26	1237149.C900_03508	3.539e-107	354.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,47JJY@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS2_k127_3552277_51	1237149.C900_03509	3.071e-23	100.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,47RU4@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS2_k127_3552277_19	1237149.C900_00775	5.146e-130	422.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes	976|Bacteroidetes	P	K -dependent Na Ca exchanger	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS2_k127_3552277_25	643867.Ftrac_2382	1.505e-108	356.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,47KRK@768503|Cytophagia	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS2_k127_3552277_39	1305737.JAFX01000001_gene2816	7.092e-51	183.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,47R44@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3552277_40	388413.ALPR1_01190	1.736e-48	175.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,47QTE@768503|Cytophagia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS2_k127_3552277_44	762903.Pedsa_3262	2.797e-41	163.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
CMS2_k127_3552277_9	1237149.C900_00922	5.681e-207	649.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,47JSB@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_3552277_23	1237149.C900_00921	3.522e-115	381.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS2_k127_3552277_22	1237149.C900_00920	1.379e-115	376.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_3552277_3	1237149.C900_00918	0.0	1571.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS2_k127_3552277_14	1237149.C900_04444	3.96e-157	504.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KGA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_3552277_54	1237149.C900_04443	6.385e-18	90.0	2EJD3@1|root,33D44@2|Bacteria,4NP3M@976|Bacteroidetes,47PW7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_3552277_1	1237149.C900_04442	0.0	1722.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,47JTE@768503|Cytophagia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS2_k127_3552277_30	1237149.C900_04441	1.069e-86	293.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS2_k127_3552277_2	643867.Ftrac_1723	0.0	1619.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS2_k127_3552277_4	1380600.AUYN01000001_gene2631	3.635e-304	952.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,1HXGZ@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS2_k127_3552277_6	313603.FB2170_00775	6.276e-270	850.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia,2PIWB@252356|Maribacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_3552277_42	1380600.AUYN01000001_gene2831	1.16e-43	162.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia	976|Bacteroidetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS2_k127_3552277_0	1124780.ANNU01000023_gene3163	0.0	1963.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,47JB7@768503|Cytophagia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS2_k127_3552277_7	643867.Ftrac_2524	2.77e-210	662.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,47M2V@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS2_k127_3552277_16	929562.Emtol_2825	6.276e-140	452.0	COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes,47U2G@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
CMS2_k127_3552277_15	1250232.JQNJ01000001_gene1811	6.382e-148	476.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes,1I089@117743|Flavobacteriia	976|Bacteroidetes	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
CMS2_k127_3552277_50	56110.Oscil6304_5921	2.062e-23	101.0	COG0298@1|root,COG0298@2|Bacteria,1G9FZ@1117|Cyanobacteria,1HDBE@1150|Oscillatoriales	1117|Cyanobacteria	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
CMS2_k127_3552277_11	504472.Slin_3880	1.059e-191	624.0	COG0068@1|root,COG0068@2|Bacteria,4NIZ1@976|Bacteroidetes,47TB5@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM NiFe hydrogenase maturation protein HypF	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
CMS2_k127_3552277_28	324925.Ppha_2052	1.643e-92	311.0	COG0378@1|root,COG0378@2|Bacteria,1FDPQ@1090|Chlorobi	1090|Chlorobi	KO	TIGRFAM hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
CMS2_k127_3552277_48	435591.BDI_1806	1.198e-25	109.0	COG0375@1|root,COG0375@2|Bacteria,4NWR5@976|Bacteroidetes,2FV7V@200643|Bacteroidia,22YT9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
CMS2_k127_3552277_12	700598.Niako_1264	1.518e-176	560.0	COG1740@1|root,COG1740@2|Bacteria,4NK1F@976|Bacteroidetes,1IRKT@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1740 Ni Fe-hydrogenase I small subunit	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
CMS2_k127_3552277_5	880073.Calab_3389	6.34e-286	887.0	COG0374@1|root,COG0374@2|Bacteria	2|Bacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hyaB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	iSbBS512_1146.SbBS512_E2342	NiFeSe_Hases
CMS2_k127_3552277_32	435591.BDI_1813	1.187e-81	279.0	COG1969@1|root,COG1969@2|Bacteria,4NIDY@976|Bacteroidetes,2FR26@200643|Bacteroidia,22VWC@171551|Porphyromonadaceae	976|Bacteroidetes	C	Domain of unknown function (DUF4405)	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
CMS2_k127_3552277_45	714943.Mucpa_5243	1.469e-40	156.0	COG0680@1|root,COG0680@2|Bacteria,4NRQY@976|Bacteroidetes,1IT7D@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0680 Ni Fe-hydrogenase maturation factor	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
CMS2_k127_3552277_38	643867.Ftrac_2626	5.512e-53	206.0	COG4251@1|root,COG4372@1|root,COG4251@2|Bacteria,COG4372@2|Bacteria,4NP5A@976|Bacteroidetes,47PX4@768503|Cytophagia	976|Bacteroidetes	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
CMS2_k127_3552277_52	388413.ALPR1_02740	1.685e-21	98.0	COG2146@1|root,COG2146@2|Bacteria,4NXMX@976|Bacteroidetes,47T2B@768503|Cytophagia	976|Bacteroidetes	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS2_k127_3552277_35	1120966.AUBU01000006_gene3137	8.629e-67	229.0	COG3565@1|root,COG3565@2|Bacteria,4NNHW@976|Bacteroidetes,47PTX@768503|Cytophagia	976|Bacteroidetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_3552277_49	1124780.ANNU01000078_gene764	9.563e-24	113.0	2BYCP@1|root,2ZAHR@2|Bacteria,4NJ23@976|Bacteroidetes,47NMK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3552277_41	1189612.A33Q_1545	3.631e-46	173.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,47QAA@768503|Cytophagia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
CMS2_k127_3552277_55	926562.Oweho_2181	4.567e-13	78.0	2AFQ6@1|root,315RZ@2|Bacteria,4PJXZ@976|Bacteroidetes,1IMQA@117743|Flavobacteriia,2PB7X@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CMS2_k127_3552277_53	926562.Oweho_2181	1.836e-19	96.0	2AFQ6@1|root,315RZ@2|Bacteria,4PJXZ@976|Bacteroidetes,1IMQA@117743|Flavobacteriia,2PB7X@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CMS2_k127_3552277_43	869213.JCM21142_215	4.095e-43	166.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,47PEP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CMS2_k127_3552277_21	1120968.AUBX01000015_gene3512	2.917e-117	396.0	COG1629@1|root,COG1629@2|Bacteria,4PM72@976|Bacteroidetes,47Y3N@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4139,DUF4140,Plug
CMS2_k127_3552277_33	1237149.C900_04853	4.239e-73	250.0	COG2316@1|root,COG2316@2|Bacteria,4NU4P@976|Bacteroidetes	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS2_k127_3552277_8	1237149.C900_01785	4.52e-208	655.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_3552277_18	1305737.JAFX01000001_gene3077	7.937e-135	443.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_3570288_9	1237149.C900_04808	7.511e-20	89.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS2_k127_3570288_6	411154.GFO_2878	4.616e-63	241.0	COG4932@1|root,COG4932@2|Bacteria,4NQ5A@976|Bacteroidetes,1IJZ3@117743|Flavobacteriia	976|Bacteroidetes	M	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,VCBS
CMS2_k127_3570288_10	714943.Mucpa_4651	2.187e-11	77.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IRNR@117747|Sphingobacteriia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SASA
CMS2_k127_3570288_3	1237149.C900_04811	8.067e-119	394.0	COG0438@1|root,COG0438@2|Bacteria,4NHPJ@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS2_k127_3570288_7	1121859.KB890754_gene826	1.996e-55	202.0	COG4122@1|root,COG4122@2|Bacteria,4NQW7@976|Bacteroidetes,47PP9@768503|Cytophagia	976|Bacteroidetes	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS2_k127_3570288_4	1124780.ANNU01000045_gene2331	1.941e-98	339.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,47MXC@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS2_k127_3570288_5	1250278.JQNQ01000001_gene2521	4.196e-85	293.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS2_k127_3570288_2	1305737.JAFX01000001_gene3626	1.899e-126	417.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS2_k127_3570288_0	1121104.AQXH01000003_gene415	1.155e-202	639.0	COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1IV0D@117747|Sphingobacteriia	976|Bacteroidetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CMS2_k127_3570288_1	1237149.C900_01857	7.108e-151	489.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS2_k127_3570288_8	1237149.C900_01803	5.698e-48	175.0	COG4891@1|root,COG4891@2|Bacteria,4NQ7V@976|Bacteroidetes,47RCX@768503|Cytophagia	976|Bacteroidetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS2_k127_364178_32	1237149.C900_04304	2.043e-49	177.0	COG1396@1|root,COG1396@2|Bacteria,4NR5F@976|Bacteroidetes,47VXZ@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_364178_30	1237149.C900_04303	2.201e-56	198.0	COG4679@1|root,COG4679@2|Bacteria,4NSFF@976|Bacteroidetes,47VI2@768503|Cytophagia	976|Bacteroidetes	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
CMS2_k127_364178_15	1286632.P278_22410	2.36e-178	569.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS2_k127_364178_33	1121904.ARBP01000007_gene3063	1.519e-45	169.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes	976|Bacteroidetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_364178_18	1237149.C900_01138	9.719e-150	484.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,47J9P@768503|Cytophagia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_364178_14	1279009.ADICEAN_03136	2.313e-183	577.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,47J9B@768503|Cytophagia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS2_k127_364178_25	1237149.C900_01135	6.949e-82	277.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,47P6K@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CMS2_k127_364178_34	1237149.C900_01134	2.588e-43	158.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
CMS2_k127_364178_6	1250278.JQNQ01000001_gene54	4.412e-287	904.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1HWZI@117743|Flavobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS2_k127_364178_36	1237149.C900_01125	5.707e-17	92.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,47SSI@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
CMS2_k127_364178_11	926549.KI421517_gene2062	9.998e-212	666.0	COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,47JSG@768503|Cytophagia	976|Bacteroidetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS2_k127_364178_3	1237149.C900_01122	0.0	1171.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,47M84@768503|Cytophagia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS2_k127_364178_5	1237149.C900_01121	3.681e-299	929.0	COG2885@1|root,COG2885@2|Bacteria,4NHWF@976|Bacteroidetes,47MMG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_364178_7	1237149.C900_05621	2.834e-263	822.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,47T90@768503|Cytophagia	976|Bacteroidetes	F	Formate--tetrahydrofolate ligase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS2_k127_364178_35	796620.VIBC2010_02003	7.838e-42	165.0	COG4123@1|root,COG4123@2|Bacteria,1PC8R@1224|Proteobacteria,1RM8S@1236|Gammaproteobacteria,1XTHE@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	yfiC	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
CMS2_k127_364178_29	1237149.C900_02216	2.264e-65	227.0	COG0431@1|root,COG0431@2|Bacteria,4NQV9@976|Bacteroidetes,47PTV@768503|Cytophagia	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CMS2_k127_364178_16	1237149.C900_05714	1.209e-163	532.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47MAI@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS2_k127_364178_19	945713.IALB_0990	2.461e-123	404.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_364178_17	1237149.C900_05870	1.332e-154	500.0	COG3193@1|root,COG3193@2|Bacteria,4NENU@976|Bacteroidetes,47N6Q@768503|Cytophagia	976|Bacteroidetes	S	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_364178_2	1237149.C900_05869	0.0	1199.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47K1M@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_364178_23	1237149.C900_02542	1.002e-86	299.0	COG1215@1|root,COG1215@2|Bacteria,4NMSY@976|Bacteroidetes,47NMB@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS2_k127_364178_26	1237149.C900_02541	1.877e-71	247.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,47P7A@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CMS2_k127_364178_24	1237149.C900_02540	1.668e-83	281.0	COG4445@1|root,COG4445@2|Bacteria,4NP3S@976|Bacteroidetes,47Q34@768503|Cytophagia	976|Bacteroidetes	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CMS2_k127_364178_27	1237149.C900_02539	9.198e-67	232.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,47M9N@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS2_k127_364178_13	1237149.C900_02538	6.704e-207	664.0	COG0508@1|root,COG0508@2|Bacteria,4PKNP@976|Bacteroidetes,47MW8@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
CMS2_k127_364178_4	742817.HMPREF9449_02821	2.991e-306	968.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,22W91@171551|Porphyromonadaceae	976|Bacteroidetes	P	CarboxypepD_reg-like domain	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_364178_12	1121912.AUHD01000007_gene518	6.827e-210	664.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1HWRV@117743|Flavobacteriia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_364178_20	1237149.C900_01386	3.815e-107	363.0	28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,47N1W@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein SusF_SusE	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
CMS2_k127_364178_1	1237149.C900_05632	0.0	1296.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
CMS2_k127_364178_22	1237149.C900_05631	3.778e-97	329.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,47KIV@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_364178_31	1124780.ANNU01000021_gene3000	5.991e-52	186.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,47Q8F@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
CMS2_k127_364178_10	1237149.C900_05629	8.216e-219	704.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,47M43@768503|Cytophagia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
CMS2_k127_364178_8	616991.JPOO01000003_gene2038	5.205e-252	786.0	COG0702@1|root,COG0702@2|Bacteria,4NHVQ@976|Bacteroidetes,1IIH3@117743|Flavobacteriia,23I0G@178469|Arenibacter	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_364178_0	1288963.ADIS_2085	0.0	1542.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KGQ@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CMS2_k127_364178_21	1237149.C900_02548	2.066e-104	353.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,47NEW@768503|Cytophagia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS2_k127_364178_38	1121904.ARBP01000004_gene872	1.071e-09	61.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS2_k127_364178_9	1237149.C900_02550	6.639e-251	787.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CMS2_k127_364178_28	926556.Echvi_4000	7.952e-66	234.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,47UKF@768503|Cytophagia	976|Bacteroidetes	S	PFAM Endonuclease Exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS2_k127_3647206_1	865937.Gilli_1323	9.399e-23	113.0	COG1345@1|root,COG1345@2|Bacteria,4PI0R@976|Bacteroidetes,1ICJE@117743|Flavobacteriia,2P7B2@244698|Gillisia	976|Bacteroidetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3647206_0	1237149.C900_01769	4.806e-318	984.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS2_k127_3651475_25	1237149.C900_02861	5.109e-22	99.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CMS2_k127_3651475_5	1237149.C900_04882	1.092e-150	490.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
CMS2_k127_3651475_12	1237149.C900_04098	3.077e-92	309.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
CMS2_k127_3651475_20	1237149.C900_04099	4.438e-54	193.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47PRC@768503|Cytophagia	976|Bacteroidetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS2_k127_3651475_24	1237149.C900_04100	3.166e-25	109.0	COG5496@1|root,COG5496@2|Bacteria,4P643@976|Bacteroidetes,47VXQ@768503|Cytophagia	976|Bacteroidetes	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3651475_7	1237149.C900_04101	5.489e-142	459.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS2_k127_3651475_0	1237149.C900_04102	0.0	1192.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47KQP@768503|Cytophagia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
CMS2_k127_3651475_14	1124780.ANNU01000044_gene531	3.133e-68	243.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
CMS2_k127_3651475_3	1237149.C900_04785	5.883e-191	601.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JKI@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_3651475_10	1150600.ADIARSV_3726	1.447e-106	355.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IPM0@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
CMS2_k127_3651475_22	1237149.C900_04788	7.617e-30	130.0	2E691@1|root,32WA1@2|Bacteria,4NT8M@976|Bacteroidetes,47R10@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3651475_1	1237149.C900_04789	0.0	1117.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS2_k127_3651475_2	1237149.C900_04790	1.4e-203	637.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47K8G@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS2_k127_3651475_21	1120965.AUBV01000001_gene3469	4.098e-36	141.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,47QPJ@768503|Cytophagia	976|Bacteroidetes	V	Type I restriction enzyme R Protein	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
CMS2_k127_3651475_6	1237149.C900_04795	7.434e-149	482.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,47JQM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS2_k127_3651475_16	1237149.C900_04796	7.231e-65	224.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,47PP4@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS2_k127_3651475_18	1237149.C900_04797	5.732e-60	213.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	ExbD
CMS2_k127_3651475_26	1237149.C900_04799	3.216e-16	82.0	2DDI9@1|root,2ZI7K@2|Bacteria,4P7HD@976|Bacteroidetes,47WMJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3651475_9	1237149.C900_04800	2.142e-114	374.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,47JQQ@768503|Cytophagia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_3651475_28	714943.Mucpa_1298	3.82e-07	52.0	COG1961@1|root,COG1961@2|Bacteria,4NHW0@976|Bacteroidetes,1IR5S@117747|Sphingobacteriia	976|Bacteroidetes	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
CMS2_k127_3651475_8	643867.Ftrac_0619	1.314e-133	434.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,47KWG@768503|Cytophagia	976|Bacteroidetes	EJ	TIGRFAM L-asparaginases, type I	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS2_k127_3651475_11	1237149.C900_04802	1.555e-95	318.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,47KE3@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS2_k127_3651475_23	1121373.KB903666_gene1280	2.919e-26	121.0	COG1215@1|root,COG1215@2|Bacteria,4NKDX@976|Bacteroidetes,47JFA@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
CMS2_k127_3651475_15	1121897.AUGO01000001_gene1214	3.588e-67	235.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia,2NSSP@237|Flavobacterium	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS2_k127_3651475_4	1237149.C900_04805	2.064e-186	590.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,47KA0@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
CMS2_k127_3651475_17	926549.KI421517_gene1529	4.063e-63	230.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,47KYN@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS2_k127_3651475_13	1237149.C900_04808	3.103e-76	261.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS2_k127_368950_3	468059.AUHA01000002_gene1279	2.244e-59	207.0	COG0346@1|root,COG0346@2|Bacteria,4NQCJ@976|Bacteroidetes,1IXZD@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_368950_4	742817.HMPREF9449_01710	1.935e-47	179.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,2FNHP@200643|Bacteroidia,22WXA@171551|Porphyromonadaceae	976|Bacteroidetes	K	Crp Fnr family	-	-	-	ko:K21556	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_368950_0	616991.JPOO01000003_gene1682	0.0	1215.0	COG3256@1|root,COG3256@2|Bacteria,4NG9H@976|Bacteroidetes,1HZ9Q@117743|Flavobacteriia	976|Bacteroidetes	P	nitric oxide reductase	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
CMS2_k127_368950_2	504472.Slin_6275	1.134e-114	376.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS2_k127_368950_1	1121904.ARBP01000026_gene688	4.48e-176	556.0	COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,47NU3@768503|Cytophagia	976|Bacteroidetes	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS2_k127_372176_27	1237149.C900_01065	2.548e-130	421.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,47KT4@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS2_k127_372176_66	926549.KI421517_gene236	7.817e-62	219.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,47PPE@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS2_k127_372176_16	1237149.C900_01063	6.53e-185	581.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,47JD5@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS2_k127_372176_42	1237149.C900_01062	5.709e-102	334.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,47K3X@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS2_k127_372176_59	1237149.C900_01061	1.976e-70	239.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,47Q07@768503|Cytophagia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS2_k127_372176_63	1237149.C900_01060	3.508e-63	218.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,47PRH@768503|Cytophagia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS2_k127_372176_97	216432.CA2559_05830	2.944e-14	73.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS2_k127_372176_79	1237149.C900_01058	9.839e-39	145.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,47RFD@768503|Cytophagia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS2_k127_372176_28	1237149.C900_01057	4.306e-129	415.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,47KDT@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS2_k127_372176_7	1237149.C900_01056	2.048e-228	713.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,47JRD@768503|Cytophagia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS2_k127_372176_68	1237149.C900_01055	4.485e-57	202.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,47PP0@768503|Cytophagia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS2_k127_372176_92	1237149.C900_01054	2.959e-19	88.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CMS2_k127_372176_46	1237149.C900_01053	9.813e-92	303.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,47M7G@768503|Cytophagia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS2_k127_372176_73	1305737.JAFX01000001_gene3393	1.095e-42	158.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,47RC9@768503|Cytophagia	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS2_k127_372176_57	1279009.ADICEAN_00777	1.944e-71	246.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,47PER@768503|Cytophagia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS2_k127_372176_67	1237149.C900_01050	3.276e-57	203.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS2_k127_372176_72	1237149.C900_01049	2.207e-43	159.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,47QB0@768503|Cytophagia	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS2_k127_372176_48	1237149.C900_01048	3.669e-90	299.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,47KSN@768503|Cytophagia	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS2_k127_372176_82	1515615.HQ41_04670	3.249e-38	146.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,2FT5V@200643|Bacteroidia,22Y4Z@171551|Porphyromonadaceae	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS2_k127_372176_61	1237149.C900_01046	7.175e-66	226.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,47PQH@768503|Cytophagia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS2_k127_372176_83	1089547.KB913013_gene2127	5.158e-36	137.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,47R6N@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS2_k127_372176_95	1237149.C900_01044	1.436e-16	80.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,47S5W@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS2_k127_372176_55	1237149.C900_01043	7.255e-75	252.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,47P74@768503|Cytophagia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS2_k127_372176_31	1237149.C900_01042	9.892e-127	408.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,47MFE@768503|Cytophagia	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS2_k127_372176_70	926556.Echvi_0250	5.954e-49	177.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,47QFH@768503|Cytophagia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS2_k127_372176_69	649349.Lbys_1826	4.342e-49	175.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,47QCA@768503|Cytophagia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS2_k127_372176_24	1237149.C900_01039	4.207e-137	439.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,47JS0@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS2_k127_372176_78	1237149.C900_01038	5.806e-41	152.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,47R4F@768503|Cytophagia	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS2_k127_372176_51	1237149.C900_01037	1.748e-84	285.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,47J8V@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS2_k127_372176_44	1237149.C900_01036	1.682e-98	326.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,47KMY@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS2_k127_372176_53	1237149.C900_03244	4.534e-79	273.0	2BK1P@1|root,32EEX@2|Bacteria,4NRXN@976|Bacteroidetes,47QMH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_372176_23	1237149.C900_03247	6.988e-144	467.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,47Y3V@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS2_k127_372176_4	1237149.C900_03248	4.249e-287	885.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,47KRX@768503|Cytophagia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS2_k127_372176_85	1237149.C900_03249	1.782e-31	124.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	ATP-synt_DE,ATP-synt_DE_N
CMS2_k127_372176_89	1237149.C900_03250	5.637e-24	104.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,47RYW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_372176_58	643867.Ftrac_1794	3.005e-71	247.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,47KV5@768503|Cytophagia	976|Bacteroidetes	J	Pseudouridine synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
CMS2_k127_372176_6	929703.KE386491_gene3582	1.034e-228	719.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,47JQE@768503|Cytophagia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CMS2_k127_372176_2	1237149.C900_03253	0.0	1056.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS2_k127_372176_18	1237149.C900_03255	1.011e-170	546.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,47KM0@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS2_k127_372176_77	649349.Lbys_3144	3.443e-41	158.0	COG0668@1|root,COG0668@2|Bacteria,4NMMB@976|Bacteroidetes,47VU0@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS2_k127_372176_74	1203606.HMPREF1526_02913	2.089e-41	160.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,36JUD@31979|Clostridiaceae	186801|Clostridia	M	Acetyltransferase GNAT family	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
CMS2_k127_372176_34	867900.Celly_2340	1.148e-120	405.0	COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,1HZJZ@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
CMS2_k127_372176_3	1121904.ARBP01000008_gene3405	0.0	1056.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47M35@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_372176_0	1317122.ATO12_16170	0.0	1173.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,2YI5F@290174|Aquimarina	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_372176_20	643867.Ftrac_1372	8.875e-157	542.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes	976|Bacteroidetes	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_8
CMS2_k127_372176_49	1122176.KB903551_gene4256	3.695e-89	308.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,1IU97@117747|Sphingobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS2_k127_372176_32	760192.Halhy_6136	1.028e-125	409.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1IQ15@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS2_k127_372176_15	1380600.AUYN01000009_gene1875	9.384e-187	592.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,1HZF9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
CMS2_k127_372176_37	1380600.AUYN01000009_gene1876	2.816e-107	356.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1HYG0@117743|Flavobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
CMS2_k127_372176_19	643867.Ftrac_2183	9.201e-165	532.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,47JJT@768503|Cytophagia	976|Bacteroidetes	P	PFAM Sodium sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS2_k127_372176_33	1237149.C900_03504	3.827e-125	406.0	COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,47MVC@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS2_k127_372176_103	1121890.AUDO01000009_gene74	1.948e-06	58.0	2ED1U@1|root,336YR@2|Bacteria,4NXS5@976|Bacteroidetes,1I49H@117743|Flavobacteriia,2NWDX@237|Flavobacterium	976|Bacteroidetes	S	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3244
CMS2_k127_372176_47	1392498.JQLH01000001_gene1807	1.876e-91	309.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS2_k127_372176_88	1237149.C900_05730	2.814e-25	107.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS2_k127_372176_40	1123057.P872_25110	1.464e-104	355.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS2_k127_372176_8	1237149.C900_05728	2.322e-227	711.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_372176_39	1121904.ARBP01000012_gene1255	8.072e-105	349.0	COG1052@1|root,COG1052@2|Bacteria,4NIHV@976|Bacteroidetes,47NBS@768503|Cytophagia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS2_k127_372176_22	307480.IW16_08780	9.499e-151	489.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1HZDM@117743|Flavobacteriia,3ZQIA@59732|Chryseobacterium	976|Bacteroidetes	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS2_k127_372176_17	1237149.C900_01604	1.492e-184	584.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,47K8V@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS2_k127_372176_36	1237149.C900_01603	6.206e-111	367.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS2_k127_372176_94	153721.MYP_173	2.211e-17	86.0	2E5E8@1|root,33066@2|Bacteria,4NWR2@976|Bacteroidetes,47S8F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_372176_12	1237149.C900_01599	2.981e-205	700.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_372176_29	1237149.C900_01598	3.11e-128	419.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_372176_21	1237149.C900_04399	9.503e-157	504.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,47KTS@768503|Cytophagia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS2_k127_372176_91	59374.Fisuc_1795	3.5e-20	95.0	COG0642@1|root,COG0784@1|root,COG2204@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_8,HisKA,Hpt,PAS_3,Response_reg,dCache_1
CMS2_k127_372176_76	1237149.C900_01631	2.833e-41	154.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,47S1E@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
CMS2_k127_372176_52	1237149.C900_01630	1.779e-82	299.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,47KA3@768503|Cytophagia	976|Bacteroidetes	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CMS2_k127_372176_26	1237149.C900_01627	1.327e-134	443.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CMS2_k127_372176_38	1279009.ADICEAN_01783	2.498e-105	353.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,47KQC@768503|Cytophagia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
CMS2_k127_372176_11	153721.MYP_3805	1.863e-210	670.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NHXQ@976|Bacteroidetes,47JFU@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS2_k127_372176_56	1237149.C900_01621	2.585e-73	254.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,47K17@768503|Cytophagia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS2_k127_372176_9	1237149.C900_01620	3.592e-226	705.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,47MQI@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS2_k127_372176_80	1237149.C900_01619	1.547e-38	146.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,47R56@768503|Cytophagia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS2_k127_372176_87	153721.MYP_3809	2.201e-30	125.0	2DNED@1|root,32UIS@2|Bacteria,4NUJS@976|Bacteroidetes,47RRD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_372176_13	1237149.C900_01617	3.793e-198	627.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,47JS3@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS2_k127_372176_50	926556.Echvi_2318	6.003e-86	303.0	COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,47M54@768503|Cytophagia	976|Bacteroidetes	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
CMS2_k127_372176_35	1189612.A33Q_1871	4.134e-111	364.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,47JF0@768503|Cytophagia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS2_k127_372176_84	1237149.C900_01614	1.094e-33	131.0	2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,47RX3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_372176_75	1237149.C900_01613	2.605e-41	155.0	COG0784@1|root,COG0784@2|Bacteria,4NQW4@976|Bacteroidetes,47Q9X@768503|Cytophagia	976|Bacteroidetes	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_372176_90	1408322.JHYK01000021_gene43	3.55e-22	112.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
CMS2_k127_372176_43	1048983.EL17_16620	1.242e-98	331.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,47KKI@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS2_k127_372176_60	1237149.C900_01610	3.253e-67	233.0	COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,47XYJ@768503|Cytophagia	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
CMS2_k127_372176_64	1237149.C900_02704	3.657e-63	223.0	COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes,47XM3@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS2_k127_372176_98	880071.Fleli_3469	9.527e-14	81.0	COG1262@1|root,COG1262@2|Bacteria,4NRP5@976|Bacteroidetes,47QCJ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_372176_25	761193.Runsl_2925	1.115e-134	439.0	COG0613@1|root,COG0613@2|Bacteria,4PMKK@976|Bacteroidetes,47NYR@768503|Cytophagia	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_372176_5	1237149.C900_02654	4.332e-247	774.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS2_k127_372176_65	1237149.C900_02655	2.674e-62	222.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911,SnoaL_4
CMS2_k127_372176_45	1237149.C900_00284	3.614e-94	316.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_372176_81	945713.IALB_0726	1.6e-38	152.0	COG2836@1|root,COG2836@2|Bacteria	2|Bacteria	K	Biogenesis protein	braZ	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2,Ferric_reduct
CMS2_k127_372176_96	1191523.MROS_1517	2.613e-16	84.0	COG3198@1|root,COG3198@2|Bacteria	2|Bacteria	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
CMS2_k127_372176_14	1237149.C900_03363	3.654e-192	610.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS2_k127_372176_62	1237149.C900_03364	6.419e-65	234.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS2_k127_372176_99	643867.Ftrac_1617	2.093e-12	68.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
CMS2_k127_372176_1	1237149.C900_03366	0.0	1121.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
CMS2_k127_372176_100	313606.M23134_07604	2.142e-12	68.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,47SPA@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS2_k127_372176_10	1121904.ARBP01000016_gene5290	8.929e-218	700.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CMS2_k127_372176_102	929703.KE386491_gene3668	6.914e-07	60.0	COG0589@1|root,COG0589@2|Bacteria,4NI7R@976|Bacteroidetes,47SXB@768503|Cytophagia	976|Bacteroidetes	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_372176_54	1237149.C900_00541	1.921e-75	263.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_372176_41	1237149.C900_05055	4.128e-104	349.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_372176_30	1237149.C900_05934	4.554e-127	445.0	COG3209@1|root,COG3291@1|root,COG3405@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CMS2_k127_3801593_2	1237149.C900_04421	2.028e-204	653.0	COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia	976|Bacteroidetes	C	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
CMS2_k127_3801593_5	1237149.C900_05585	6.105e-174	563.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
CMS2_k127_3801593_28	1541065.JRFE01000068_gene2700	1.658e-41	156.0	2CCSR@1|root,32RWC@2|Bacteria,1G7HK@1117|Cyanobacteria,3VN4G@52604|Pleurocapsales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS2_k127_3801593_16	1121007.AUML01000006_gene3000	4.062e-97	328.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia,2YJ2Y@290174|Aquimarina	976|Bacteroidetes	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS2_k127_3801593_10	269798.CHU_0163	1.129e-134	448.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CMS2_k127_3801593_6	760192.Halhy_2292	1.3e-168	544.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1IRN9@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase M1 membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
CMS2_k127_3801593_20	761193.Runsl_2490	1.286e-73	262.0	COG3876@1|root,COG3876@2|Bacteria,4P1CP@976|Bacteroidetes,47U2C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS2_k127_3801593_0	1313301.AUGC01000013_gene1288	0.0	1062.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF3991,Plug,TonB_dep_Rec,Toprim_2
CMS2_k127_3801593_12	1313301.AUGC01000013_gene1287	2.679e-131	432.0	28II1@1|root,2Z8J7@2|Bacteria,4NFJH@976|Bacteroidetes	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
CMS2_k127_3801593_8	517418.Ctha_0124	2.21e-143	464.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS2_k127_3801593_31	1121904.ARBP01000006_gene3781	8.96e-21	94.0	COG0640@1|root,COG0640@2|Bacteria,4NSHB@976|Bacteroidetes,47S82@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS2_k127_3801593_32	1460634.JCM19037_3455	1.438e-20	93.0	COG0425@1|root,COG0425@2|Bacteria,1VEEC@1239|Firmicutes,4HNQT@91061|Bacilli	91061|Bacilli	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
CMS2_k127_3801593_22	324925.Ppha_2326	8.185e-70	240.0	COG2210@1|root,COG2210@2|Bacteria,1FE9Q@1090|Chlorobi	1090|Chlorobi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS2_k127_3801593_24	309801.trd_0142	1.611e-60	222.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
CMS2_k127_3801593_33	1108045.GORHZ_118_00100	4.51e-19	92.0	COG2044@1|root,COG2044@2|Bacteria,2H50T@201174|Actinobacteria	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE_2
CMS2_k127_3801593_27	517418.Ctha_0140	1.115e-47	175.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS2_k127_3801593_13	517418.Ctha_0138	4.18e-106	348.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	dld	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
CMS2_k127_3801593_4	1051632.TPY_3530	2.294e-182	577.0	COG2048@1|root,COG2048@2|Bacteria,1V67B@1239|Firmicutes,248DI@186801|Clostridia	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS2_k127_3801593_9	562970.Btus_2496	4.93e-139	450.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Pyr_redox_2
CMS2_k127_3801593_26	517418.Ctha_0134	6.065e-54	198.0	2DPCA@1|root,331H2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3801593_3	309801.trd_0150	1.264e-187	594.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS2_k127_3801593_30	436114.SYO3AOP1_0897	4.537e-23	104.0	COG0509@1|root,COG0509@2|Bacteria,2G55V@200783|Aquificae	200783|Aquificae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS2_k127_3801593_14	882083.SacmaDRAFT_1928	6.039e-104	346.0	COG1856@1|root,COG1856@2|Bacteria,2H3RG@201174|Actinobacteria	201174|Actinobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
CMS2_k127_3801593_23	517418.Ctha_0128	8.922e-66	238.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,DUF116
CMS2_k127_3801593_34	1123368.AUIS01000031_gene1415	6.702e-19	92.0	2ECQ3@1|root,31692@2|Bacteria,1PX3E@1224|Proteobacteria,1T8SY@1236|Gammaproteobacteria,2NDD8@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3801593_7	882083.SacmaDRAFT_1930	3.449e-149	480.0	COG2516@1|root,COG2516@2|Bacteria,2H2JZ@201174|Actinobacteria	201174|Actinobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS2_k127_3801593_21	517418.Ctha_0132	6.953e-71	247.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	iAF987.Gmet_2266	CCG,ETF,Fer4_8
CMS2_k127_3801593_18	517418.Ctha_0131	5.733e-91	309.0	COG2025@1|root,COG2025@2|Bacteria,1FE6B@1090|Chlorobi	1090|Chlorobi	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS2_k127_3801593_1	882083.SacmaDRAFT_1933	2.107e-223	713.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4DYWI@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS2_k127_3801593_15	1123248.KB893381_gene961	5.764e-103	341.0	2DB9P@1|root,2Z7Y1@2|Bacteria,4NHQN@976|Bacteroidetes,1IYRD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_3801593_11	880070.Cycma_3799	6.368e-134	439.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,47N8C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3801593_19	985255.APHJ01000022_gene3180	5.453e-90	304.0	COG1216@1|root,COG1216@2|Bacteria,4NRM6@976|Bacteroidetes,1I3NR@117743|Flavobacteriia	976|Bacteroidetes	S	Putative rhamnosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhamno_transf
CMS2_k127_3801593_29	1121904.ARBP01000008_gene3223	2.833e-33	143.0	COG4251@1|root,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47MXR@768503|Cytophagia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
CMS2_k127_3801593_25	177437.HRM2_19520	7.864e-60	214.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,42V1Y@68525|delta/epsilon subdivisions,2WQ41@28221|Deltaproteobacteria,2MKZG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CMS2_k127_3801593_17	1124780.ANNU01000037_gene99	4.396e-94	313.0	COG0610@1|root,COG0610@2|Bacteria,4NFJ8@976|Bacteroidetes,47KT2@768503|Cytophagia	976|Bacteroidetes	L	Type I restriction enzyme R Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3387,HSDR_N,ResIII
CMS2_k127_3835587_6	1123057.P872_11935	6.154e-09	58.0	2FKSJ@1|root,34CD3@2|Bacteria,4P89S@976|Bacteroidetes,47WSU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3835587_2	1237149.C900_05006	1.277e-45	171.0	COG2318@1|root,COG2318@2|Bacteria,4NQ7Y@976|Bacteroidetes	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CMS2_k127_3835587_1	1265503.KB905166_gene934	1.203e-104	349.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
CMS2_k127_3835587_8	983548.Krodi_1040	1.42e-06	52.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,37EC0@326319|Dokdonia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_3835587_5	313603.FB2170_11651	1.676e-14	76.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI8X@252356|Maribacter	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_3835587_0	1454007.JAUG01000080_gene2278	1.523e-197	623.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_3835587_7	880070.Cycma_1810	1.339e-07	60.0	28NR7@1|root,2ZBQI@2|Bacteria,4NMCH@976|Bacteroidetes,47WBS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3835587_3	1317122.ATO12_05715	3.245e-37	143.0	COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,1I3SY@117743|Flavobacteriia,2YJI3@290174|Aquimarina	976|Bacteroidetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_3835587_4	313624.NSP_16770	2.427e-35	139.0	COG0614@1|root,COG0614@2|Bacteria,1G79B@1117|Cyanobacteria,1HNFV@1161|Nostocales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CMS2_k127_388115_2	1237149.C900_03613	1.683e-175	575.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia	976|Bacteroidetes	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
CMS2_k127_388115_6	1237149.C900_03614	1.736e-98	330.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_388115_12	643867.Ftrac_0101	7.418e-44	165.0	2DM4T@1|root,31QCU@2|Bacteria,4PK44@976|Bacteroidetes,47QH5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_388115_10	1237149.C900_01572	2.987e-49	181.0	COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes,47QR6@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_388115_7	1237149.C900_01575	1.45e-75	255.0	2C4H4@1|root,32CX0@2|Bacteria,4NRZ7@976|Bacteroidetes,47SG5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_388115_1	1237149.C900_01576	8.739e-178	565.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,47JSE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nucleoside recognition	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
CMS2_k127_388115_9	649639.Bcell_3463	3.422e-62	224.0	COG3386@1|root,COG3386@2|Bacteria,1V1TK@1239|Firmicutes,4HG0A@91061|Bacilli,1ZAVX@1386|Bacillus	91061|Bacilli	G	SMP-30/Gluconolaconase/LRE-like region	yvrE	GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
CMS2_k127_388115_11	376686.Fjoh_4594	3.576e-45	171.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1HY0K@117743|Flavobacteriia,2NSQY@237|Flavobacterium	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS2_k127_388115_13	1033802.SSPSH_000127	2.697e-17	84.0	COG4281@1|root,COG4281@2|Bacteria,1MZPP@1224|Proteobacteria,1SAD8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ACBP
CMS2_k127_388115_0	1237149.C900_01580	5.918e-226	706.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS2_k127_388115_5	1237149.C900_01581	2.852e-121	394.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,47MT6@768503|Cytophagia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS2_k127_388115_8	1237149.C900_01582	1.555e-73	258.0	COG0457@1|root,COG0457@2|Bacteria	1237149.C900_01582|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_388115_3	1120966.AUBU01000001_gene1102	2.108e-156	498.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,47JQN@768503|Cytophagia	976|Bacteroidetes	G	PFAM Transketolase, C-terminal domain	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_388115_4	1237149.C900_05650	1.32e-138	444.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,47JJD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS2_k127_393328_55	1434325.AZQN01000001_gene636	1.1e-42	163.0	COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,47PF2@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS2_k127_393328_54	1185876.BN8_05719	1.851e-44	166.0	COG0607@1|root,COG0607@2|Bacteria,4NQ61@976|Bacteroidetes,47Q3A@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_393328_40	643867.Ftrac_3362	1.803e-94	325.0	COG1216@1|root,COG1216@2|Bacteria,4PKUG@976|Bacteroidetes,47YDT@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS2_k127_393328_14	1237149.C900_04734	6.999e-189	601.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,47MJK@768503|Cytophagia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS2_k127_393328_41	1237149.C900_04733	2.557e-91	308.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_393328_28	1237149.C900_03379	6.169e-125	413.0	COG3203@1|root,COG3203@2|Bacteria,4NDYW@976|Bacteroidetes,47JMP@768503|Cytophagia	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS2_k127_393328_63	1121007.AUML01000022_gene844	3.837e-12	69.0	2EAEB@1|root,334HW@2|Bacteria,4NVVS@976|Bacteroidetes,1I529@117743|Flavobacteriia,2YJZS@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_393328_0	1286632.P278_17120	0.0	1248.0	COG0243@1|root,COG0243@2|Bacteria,4NG4N@976|Bacteroidetes,1HXQ0@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS2_k127_393328_44	1178825.ALIH01000002_gene934	1.81e-73	254.0	COG3043@1|root,COG3043@2|Bacteria,4NG82@976|Bacteroidetes,1HZDY@117743|Flavobacteriia	976|Bacteroidetes	C	anaerobic respiration	-	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	Cytochrome_C554,NapB
CMS2_k127_393328_50	1443665.JACA01000001_gene2624	1.178e-59	213.0	28JYU@1|root,2Z9NZ@2|Bacteria,4NKTR@976|Bacteroidetes,1I0RC@117743|Flavobacteriia,2YJ0V@290174|Aquimarina	976|Bacteroidetes	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
CMS2_k127_393328_17	1121007.AUML01000022_gene840	1.094e-169	537.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,1I01K@117743|Flavobacteriia,2YH5Q@290174|Aquimarina	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
CMS2_k127_393328_16	1121007.AUML01000022_gene839	3.2e-184	583.0	COG5557@1|root,COG5557@2|Bacteria,4NG2Z@976|Bacteroidetes,1I0YA@117743|Flavobacteriia,2YIPA@290174|Aquimarina	976|Bacteroidetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS2_k127_393328_47	1121931.AUHG01000015_gene1183	2.697e-64	224.0	COG0251@1|root,COG0251@2|Bacteria,4NP23@976|Bacteroidetes,1I1QV@117743|Flavobacteriia	976|Bacteroidetes	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,YjgF_endoribonc
CMS2_k127_393328_24	1304874.JAFY01000005_gene1625	2.245e-145	471.0	COG0520@1|root,COG0520@2|Bacteria,3TAAX@508458|Synergistetes	508458|Synergistetes	E	TIGRFAM cysteine desulfurase family protein, VC1184 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_393328_30	1189612.A33Q_1093	7.937e-120	390.0	COG3970@1|root,COG3970@2|Bacteria,4NGTH@976|Bacteroidetes,47MQU@768503|Cytophagia	976|Bacteroidetes	S	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
CMS2_k127_393328_53	1408473.JHXO01000011_gene2983	9.531e-46	167.0	COG3070@1|root,COG3070@2|Bacteria,4NQWP@976|Bacteroidetes,2FTFF@200643|Bacteroidia	976|Bacteroidetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS2_k127_393328_65	880070.Cycma_1589	2.068e-05	48.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_393328_61	643867.Ftrac_3221	3.864e-29	120.0	COG2149@1|root,COG2149@2|Bacteria,4NWFQ@976|Bacteroidetes,47SDS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
CMS2_k127_393328_19	926549.KI421517_gene466	7.166e-165	529.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M9H@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_393328_5	1237149.C900_04547	9.48e-257	797.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,47JKQ@768503|Cytophagia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS2_k127_393328_45	1237149.C900_04546	3.725e-73	252.0	2DPU6@1|root,333E2@2|Bacteria,4NW9K@976|Bacteroidetes,47RVJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_393328_11	1124780.ANNU01000016_gene1814	8.586e-199	634.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS2_k127_393328_29	1237149.C900_04543	8.545e-124	400.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS2_k127_393328_4	1237149.C900_04542	5.108e-258	802.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,47KAH@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS2_k127_393328_10	1121897.AUGO01000004_gene992	8.224e-205	645.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1HX25@117743|Flavobacteriia,2NT9E@237|Flavobacterium	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
CMS2_k127_393328_21	1237149.C900_00792	4.583e-163	519.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,47M9W@768503|Cytophagia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS2_k127_393328_33	1237149.C900_00793	1.107e-108	367.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,47PAS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS2_k127_393328_6	1237149.C900_03443	4.271e-226	715.0	COG1729@1|root,COG1729@2|Bacteria,4PKMW@976|Bacteroidetes,47JRZ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
CMS2_k127_393328_38	1237149.C900_03442	4.55e-102	351.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,47KXU@768503|Cytophagia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
CMS2_k127_393328_42	643867.Ftrac_2377	5.25e-90	304.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS2_k127_393328_2	1237149.C900_03440	4.889e-301	932.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS2_k127_393328_57	1237149.C900_03439	5.048e-40	153.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,47Q9Q@768503|Cytophagia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
CMS2_k127_393328_49	1237149.C900_03438	7.605e-63	217.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS2_k127_393328_1	1237149.C900_03437	9.43e-308	980.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,47NNE@768503|Cytophagia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
CMS2_k127_393328_56	1237149.C900_00058	1.637e-42	160.0	2CH3Z@1|root,32RP9@2|Bacteria,4NQUA@976|Bacteroidetes,47PY7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
CMS2_k127_393328_9	1237149.C900_00818	1.067e-215	682.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CMS2_k127_393328_13	1237149.C900_03511	1.355e-193	608.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47K4J@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_393328_8	1237149.C900_03512	5.253e-218	682.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS2_k127_393328_15	1237149.C900_03513	4.839e-188	589.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS2_k127_393328_18	743722.Sph21_1051	7.465e-167	529.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS2_k127_393328_22	929703.KE386491_gene1463	1.094e-153	490.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,47JPC@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS2_k127_393328_46	1317122.ATO12_17605	6e-71	244.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,1I4QS@117743|Flavobacteriia,2YKPE@290174|Aquimarina	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS2_k127_393328_36	1121904.ARBP01000022_gene3484	7.233e-103	340.0	COG3568@1|root,COG3568@2|Bacteria,4NMQ9@976|Bacteroidetes,47M9K@768503|Cytophagia	976|Bacteroidetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS2_k127_393328_27	616991.JPOO01000001_gene4356	2.894e-126	412.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,1HYIQ@117743|Flavobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CMS2_k127_393328_62	1123057.P872_00935	5.697e-20	91.0	2CIDP@1|root,32S8D@2|Bacteria,4NS8C@976|Bacteroidetes,47S8I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_393328_58	1286632.P278_15490	9.459e-39	147.0	COG0526@1|root,COG0526@2|Bacteria,4NQ6I@976|Bacteroidetes,1I2YE@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin	trxA_1	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CMS2_k127_393328_32	319236.JCM19294_1446	7.971e-110	358.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,1HWZW@117743|Flavobacteriia,3HJI2@363408|Nonlabens	976|Bacteroidetes	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS2_k127_393328_51	1237149.C900_00748	8e-53	194.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
CMS2_k127_393328_3	1237149.C900_00749	2.168e-259	814.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_393328_23	1237149.C900_00751	3.575e-147	477.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,47MV0@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_393328_48	1223410.KN050846_gene961	2.778e-64	226.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_393328_43	1237149.C900_02856	4.836e-89	301.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,47JZC@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS2_k127_393328_60	471854.Dfer_2660	9.618e-37	154.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,47JR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_393328_37	1237149.C900_02858	3.49e-102	338.0	COG2227@1|root,COG2227@2|Bacteria,4NFHE@976|Bacteroidetes,47JIB@768503|Cytophagia	976|Bacteroidetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS2_k127_393328_20	926549.KI421517_gene1597	5.088e-164	533.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,47JTP@768503|Cytophagia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CMS2_k127_393328_34	1237149.C900_00804	1.42e-108	357.0	COG0106@1|root,COG0106@2|Bacteria,4NK0E@976|Bacteroidetes,47NT9@768503|Cytophagia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_393328_12	1237149.C900_00811	3.801e-198	624.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,47JBT@768503|Cytophagia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS2_k127_393328_25	1121897.AUGO01000001_gene1445	3.595e-139	447.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia,2NS9D@237|Flavobacterium	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS2_k127_393328_59	880073.Calab_0150	4.448e-38	154.0	COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS2_k127_393328_52	1121875.KB907546_gene2611	1.294e-52	192.0	COG1082@1|root,COG1082@2|Bacteria,4P3HU@976|Bacteroidetes,1I99U@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_393328_39	1237149.C900_03634	8.96e-100	331.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,47PW3@768503|Cytophagia	976|Bacteroidetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C,YkuD
CMS2_k127_393328_31	649349.Lbys_0113	2.269e-110	362.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,47K38@768503|Cytophagia	976|Bacteroidetes	K	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
CMS2_k127_393328_26	1121904.ARBP01000003_gene6266	4.441e-127	415.0	COG2755@1|root,COG2755@2|Bacteria,4NEAZ@976|Bacteroidetes,47K65@768503|Cytophagia	976|Bacteroidetes	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_3
CMS2_k127_393328_35	985255.APHJ01000021_gene1587	2.201e-105	350.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia,2P7I0@244698|Gillisia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_393328_7	746697.Aeqsu_2887	1.441e-224	702.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	sad	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_393328_64	1250006.JHZZ01000001_gene1778	1.438e-06	50.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,1I2JH@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
CMS2_k127_397055_11	1178825.ALIH01000008_gene708	1.97e-15	80.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1HYKY@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS2_k127_397055_9	1237149.C900_01569	1.403e-59	210.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS2_k127_397055_0	1237149.C900_01570	0.0	1067.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
CMS2_k127_397055_2	1237149.C900_00016	3.05e-208	654.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS2_k127_397055_3	866536.Belba_2643	7.498e-143	460.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,47K71@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_397055_10	1296416.JACB01000037_gene1393	5.091e-37	142.0	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1I3Q8@117743|Flavobacteriia,2YJVC@290174|Aquimarina	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS2_k127_397055_7	929703.KE386491_gene2542	5.086e-89	300.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,47JB0@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_397055_13	927658.AJUM01000047_gene2944	1.33e-12	76.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_397055_15	307480.IW16_10180	1.018e-05	56.0	COG4412@1|root,COG4412@2|Bacteria,4PM4A@976|Bacteroidetes,1IJJ2@117743|Flavobacteriia,3ZUP5@59732|Chryseobacterium	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,FTP,PA,Peptidase_M36,Peptidase_M6
CMS2_k127_397055_6	109760.SPPG_04804T0	7.233e-90	307.0	COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi	4751|Fungi	Q	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS2_k127_397055_14	1237149.C900_01204	3.89e-06	57.0	COG4700@1|root,COG4700@2|Bacteria,4PPNH@976|Bacteroidetes,47YQ2@768503|Cytophagia	976|Bacteroidetes	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_397055_12	1237149.C900_01204	8.975e-13	77.0	COG4700@1|root,COG4700@2|Bacteria,4PPNH@976|Bacteroidetes,47YQ2@768503|Cytophagia	976|Bacteroidetes	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_397055_5	1237149.C900_01205	1.664e-121	397.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,47NJQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS2_k127_397055_4	1237149.C900_05806	6.126e-122	397.0	COG1108@1|root,COG1108@2|Bacteria,4NH3D@976|Bacteroidetes,47JST@768503|Cytophagia	976|Bacteroidetes	P	ABC 3 transport family	mntD	-	-	ko:K11709	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
CMS2_k127_397055_1	1237149.C900_03344	1.511e-254	811.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47K6V@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CMS2_k127_397055_8	929703.KE386491_gene2088	8.758e-60	215.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,47NSP@768503|Cytophagia	976|Bacteroidetes	J	PFAM SpoU rRNA Methylase family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS2_k127_3977381_1	153721.MYP_1562	1.553e-121	398.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS2_k127_3977381_2	1237149.C900_01804	1.072e-113	379.0	28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,47M50@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CMS2_k127_3977381_6	1237149.C900_01860	2.419e-75	259.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,47KXS@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS2_k127_3977381_9	1237149.C900_05879	3.83e-38	147.0	COG0824@1|root,COG0824@2|Bacteria,4NT54@976|Bacteroidetes,47RRM@768503|Cytophagia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
CMS2_k127_3977381_0	1239962.C943_03415	0.0	1249.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,47KA7@768503|Cytophagia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS2_k127_3977381_7	1237149.C900_00906	1.173e-49	181.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,47Q8I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Prokaryotic dksA traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS2_k127_3977381_5	1237149.C900_00905	1.006e-83	280.0	COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,47NG4@768503|Cytophagia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS2_k127_3977381_4	1124780.ANNU01000005_gene2527	1.739e-100	334.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,47JIE@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_3977381_3	1237149.C900_03175	8.98e-105	355.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,OmpA,PKD,Peptidase_M43,VPEP,fn3
CMS2_k127_3977381_11	1260251.SPISAL_06630	1.359e-10	66.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1WVZG@135613|Chromatiales	135613|Chromatiales	T	phosphate regulon transcriptional regulatory protein PhoB	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_3977381_8	153721.MYP_3441	6.33e-48	183.0	COG0642@1|root,COG2205@2|Bacteria,4NQHU@976|Bacteroidetes,47R06@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS2_k127_3977381_10	1237149.C900_03174	3.136e-15	81.0	COG5608@1|root,COG5608@2|Bacteria,4NVQ5@976|Bacteroidetes	976|Bacteroidetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
CMS2_k127_3981797_4	761193.Runsl_4249	2.866e-149	488.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,47MRG@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS2_k127_3981797_6	880070.Cycma_4469	1.948e-63	220.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PA8@768503|Cytophagia	976|Bacteroidetes	C	2Fe-2S -binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_3981797_0	1122176.KB903531_gene3054	6.887e-321	996.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IPWF@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_3981797_1	1123057.P872_05555	1.095e-264	825.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,47JQ2@768503|Cytophagia	976|Bacteroidetes	E	PFAM glucose-methanol-choline oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
CMS2_k127_3981797_8	1166018.FAES_0841	2.006e-45	170.0	28KSE@1|root,2ZBRS@2|Bacteria,4NNCR@976|Bacteroidetes,47P8I@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_3981797_5	1341181.FLJC2902T_16220	1.057e-66	238.0	28PX6@1|root,2ZCH8@2|Bacteria,4NNE6@976|Bacteroidetes,1I2RQ@117743|Flavobacteriia,2NTY4@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS2_k127_3981797_10	693746.OBV_00830	0.0001341	45.0	COG3949@1|root,COG3949@2|Bacteria,1UY6A@1239|Firmicutes,25DKX@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3981797_9	1443665.JACA01000001_gene3029	3.617e-21	102.0	2C257@1|root,32R9T@2|Bacteria,4NRWH@976|Bacteroidetes,1I3GT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_15
CMS2_k127_3981797_2	616991.JPOO01000003_gene1766	9.754e-220	691.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia,23G90@178469|Arenibacter	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS2_k127_3981797_3	1048983.EL17_11625	2.508e-154	495.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,47MUI@768503|Cytophagia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS2_k127_3981797_7	880070.Cycma_4845	1.414e-47	179.0	COG2133@1|root,COG2133@2|Bacteria,4PNNH@976|Bacteroidetes,47KNR@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_4009425_1	1237149.C900_04582	1.581e-115	376.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_4009425_2	1237149.C900_04581	3.923e-96	325.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS2_k127_4009425_3	1237149.C900_02855	1.715e-54	201.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,47MHM@768503|Cytophagia	976|Bacteroidetes	M	Lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS2_k127_4009425_0	1124780.ANNU01000017_gene1937	1.232e-162	518.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,47KHN@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
CMS2_k127_4009425_4	269798.CHU_3454	7.926e-17	82.0	COG4251@1|root,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,47NVD@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS2_k127_4065808_16	468059.AUHA01000006_gene2965	6.467e-14	77.0	2EHX5@1|root,33BNR@2|Bacteria,4NXNQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4065808_4	1121904.ARBP01000001_gene5644	3.893e-197	640.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,47MVB@768503|Cytophagia	976|Bacteroidetes	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS2_k127_4065808_10	592029.DDD_3464	2.341e-74	266.0	28JIH@1|root,2Z9BT@2|Bacteria,4NIF7@976|Bacteroidetes,1HYCU@117743|Flavobacteriia,3HJQS@363408|Nonlabens	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
CMS2_k127_4065808_3	504472.Slin_6586	2.066e-240	771.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,47JFD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
CMS2_k127_4065808_7	1121904.ARBP01000007_gene2928	1.011e-125	412.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,47JVV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CMS2_k127_4065808_5	1042376.AFPK01000036_gene1842	1.337e-161	515.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,1HZEI@117743|Flavobacteriia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4065808_11	1239962.C943_03666	7.616e-61	215.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,47PXK@768503|Cytophagia	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS2_k127_4065808_1	1296415.JACC01000027_gene1336	2.868e-315	970.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2YGW5@290174|Aquimarina	976|Bacteroidetes	E	Glutamine amidotransferase domain	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS2_k127_4065808_6	1237149.C900_05201	1.392e-127	421.0	COG1524@1|root,COG1524@2|Bacteria,4NFRQ@976|Bacteroidetes,47JI2@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS2_k127_4065808_12	1237149.C900_01127	2.341e-43	164.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS2_k127_4065808_2	1237149.C900_01133	1.131e-297	920.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47M5V@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_4065808_9	1237149.C900_00401	1.828e-76	259.0	COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,47PI0@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS2_k127_4065808_0	1237149.C900_03056	0.0	1260.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS2_k127_4065808_13	1408433.JHXV01000010_gene595	3.766e-36	142.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1I2YC@117743|Flavobacteriia,2PB73@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS2_k127_4065808_8	1237149.C900_00316	2.795e-114	371.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS2_k127_4065808_14	504487.JCM19302_3076	1.032e-28	120.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1I1ZF@117743|Flavobacteriia	976|Bacteroidetes	H	synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS2_k127_4088046_5	1279009.ADICEAN_01125	3.107e-85	284.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47JN7@768503|Cytophagia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS2_k127_4088046_2	1189612.A33Q_3163	2.699e-124	409.0	COG1373@1|root,COG1373@2|Bacteria,4NE3E@976|Bacteroidetes,47P2P@768503|Cytophagia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
CMS2_k127_4088046_4	1279009.ADICEAN_01124	1.032e-107	355.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,47NFE@768503|Cytophagia	976|Bacteroidetes	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS2_k127_4088046_6	485916.Dtox_2859	2.422e-63	231.0	COG0438@1|root,COG0438@2|Bacteria,1V5W1@1239|Firmicutes,24HV6@186801|Clostridia,263ZC@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
CMS2_k127_4088046_3	643867.Ftrac_2414	8.128e-122	404.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4088046_1	1237149.C900_02863	3.188e-157	504.0	COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,47Y4H@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS2_k127_4088046_0	1237149.C900_02861	0.0	1229.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CMS2_k127_4111243_13	1121104.AQXH01000002_gene660	8.902e-113	370.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS2_k127_4111243_28	1121286.AUMT01000001_gene410	1.686e-48	175.0	COG3254@1|root,COG3254@2|Bacteria,4NQAA@976|Bacteroidetes,1I46Z@117743|Flavobacteriia,3ZTP7@59732|Chryseobacterium	976|Bacteroidetes	S	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
CMS2_k127_4111243_18	1121904.ARBP01000019_gene2741	1.924e-91	307.0	COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,47JGG@768503|Cytophagia	976|Bacteroidetes	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS2_k127_4111243_22	1237149.C900_05616	1.944e-64	227.0	COG2353@1|root,COG2353@2|Bacteria,4NPGK@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS2_k127_4111243_23	1239962.C943_01794	5.983e-60	213.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_5	1122176.KB903565_gene3355	2.813e-183	589.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,1IW25@117747|Sphingobacteriia	976|Bacteroidetes	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS2_k127_4111243_15	620914.JH621271_gene1734	1.33e-101	341.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,1HWNT@117743|Flavobacteriia,2YGY7@290174|Aquimarina	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
CMS2_k127_4111243_21	1250232.JQNJ01000001_gene1069	5.784e-66	234.0	28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,1HZ05@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_7	1047013.AQSP01000139_gene2323	1.98e-177	580.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_4111243_2	1121904.ARBP01000004_gene900	2.256e-267	831.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS2_k127_4111243_19	616991.JPOO01000003_gene845	1.281e-85	288.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia,23H0X@178469|Arenibacter	976|Bacteroidetes	S	Alanine racemase, N-terminal domain	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS2_k127_4111243_8	1237149.C900_05470	6.392e-175	554.0	COG1363@1|root,COG1363@2|Bacteria,4NIW2@976|Bacteroidetes,47JPS@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS2_k127_4111243_32	1237149.C900_01186	3.691e-37	142.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,47RA2@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein, GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_34	1237149.C900_05847	1.736e-25	113.0	2ESEN@1|root,33JZB@2|Bacteria,4NZ9T@976|Bacteroidetes,47VE9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_10	1237149.C900_00289	3.984e-155	524.0	COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,47YDH@768503|Cytophagia	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_V_gamma,PDDEXK_1
CMS2_k127_4111243_29	391587.KAOT1_01270	3.407e-48	178.0	COG0457@1|root,COG0457@2|Bacteria,4NNWA@976|Bacteroidetes,1I350@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_17	1237149.C900_02634	2.673e-95	317.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,47PQP@768503|Cytophagia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_4111243_35	867900.Celly_0380	5.58e-21	103.0	2FKA3@1|root,34BXQ@2|Bacteria,4P68W@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_26	1279009.ADICEAN_02508	4.199e-51	184.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47PG1@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K01802,ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS2_k127_4111243_31	1237149.C900_05817	1.982e-42	162.0	COG0457@1|root,COG0457@2|Bacteria,4NN6J@976|Bacteroidetes,47PCR@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS2_k127_4111243_16	1237149.C900_05815	5.476e-96	321.0	2DBU8@1|root,2ZB4S@2|Bacteria,4PKQU@976|Bacteroidetes,47Y2Z@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS2_k127_4111243_11	487796.Flav2ADRAFT_0527	2.313e-142	454.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CMS2_k127_4111243_25	1237149.C900_05813	2.142e-53	202.0	COG0438@1|root,COG0438@2|Bacteria,4NMMT@976|Bacteroidetes,47PDF@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS2_k127_4111243_20	1237149.C900_05811	1.381e-83	282.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS2_k127_4111243_14	1237149.C900_05810	8.941e-106	351.0	COG0803@1|root,COG0803@2|Bacteria,4NGMC@976|Bacteroidetes,47M6W@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the bacterial solute-binding protein 9 family	mntA	-	-	ko:K09815,ko:K11707	ko02010,map02010	M00242,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS2_k127_4111243_12	1237149.C900_05809	1.092e-125	407.0	COG1121@1|root,COG1121@2|Bacteria,4NHZ9@976|Bacteroidetes,47KSI@768503|Cytophagia	976|Bacteroidetes	P	ATPases associated with a variety of cellular activities	troB	-	3.6.3.35	ko:K11710,ko:K19973	ko02010,map02010	M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
CMS2_k127_4111243_6	1237149.C900_05808	1.807e-179	571.0	COG1108@1|root,COG1321@1|root,COG1108@2|Bacteria,COG1321@2|Bacteria,4NH3D@976|Bacteroidetes,47MU3@768503|Cytophagia	976|Bacteroidetes	KP	ABC 3 transport family	mntC	-	-	ko:K11708	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3,Fe_dep_repr_C
CMS2_k127_4111243_9	1237149.C900_04745	1.175e-155	501.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47KYR@768503|Cytophagia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_4111243_3	1237149.C900_04746	1.055e-225	704.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,47MEQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_33	1121904.ARBP01000005_gene4824	6.321e-35	137.0	2DPIW@1|root,332A0@2|Bacteria,4NUNN@976|Bacteroidetes,47T5G@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111243_1	1237149.C900_00620	0.0	1011.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,47KIQ@768503|Cytophagia	976|Bacteroidetes	G	Trehalose-phosphatase	otsB	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
CMS2_k127_4111243_4	313606.M23134_00615	1.06e-217	702.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_4111243_0	1124780.ANNU01000037_gene153	0.0	1903.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
CMS2_k127_4111243_30	886377.Murru_0046	1.445e-44	167.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1I28K@117743|Flavobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CMS2_k127_4111243_24	1237149.C900_03646	7.482e-57	199.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,47QDT@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS2_k127_4111243_27	865937.Gilli_3289	2.903e-49	179.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2P6Z2@244698|Gillisia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS2_k127_4111723_43	1341155.FSS13T_23940	6.011e-65	246.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
CMS2_k127_4111723_34	755732.Fluta_1531	1.378e-88	301.0	COG3012@1|root,COG3228@1|root,COG3012@2|Bacteria,COG3228@2|Bacteria,4NGM9@976|Bacteroidetes,1HYPW@117743|Flavobacteriia,2PAS4@246874|Cryomorphaceae	976|Bacteroidetes	S	Glucose-regulated metallo-peptidase M90	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
CMS2_k127_4111723_73	1506583.JQJY01000008_gene3939	4.19e-06	49.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,1HY22@117743|Flavobacteriia,2NUAX@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
CMS2_k127_4111723_6	1237149.C900_03447	1.036e-236	748.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
CMS2_k127_4111723_66	1237149.C900_03448	1.602e-21	95.0	COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,47RUN@768503|Cytophagia	976|Bacteroidetes	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS2_k127_4111723_0	1250232.JQNJ01000001_gene498	0.0	1566.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_4111723_32	485918.Cpin_1727	5.18e-92	307.0	COG0637@1|root,COG0637@2|Bacteria,4PM6Z@976|Bacteroidetes	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS2_k127_4111723_38	1122179.KB890438_gene1586	7.359e-75	255.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1IQD8@117747|Sphingobacteriia	976|Bacteroidetes	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS2_k127_4111723_56	143224.JQMD01000002_gene4064	2.112e-43	171.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS2_k127_4111723_69	925409.KI911562_gene479	3.882e-17	83.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_4111723_54	1237149.C900_04011	2.579e-49	182.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,47QAU@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_4111723_68	1237149.C900_04012	1.726e-17	86.0	2DQ9W@1|root,335IW@2|Bacteria,4NX9R@976|Bacteroidetes,47SCH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111723_12	1121904.ARBP01000028_gene1668	3.354e-148	475.0	COG2041@1|root,COG2041@2|Bacteria,4NHQB@976|Bacteroidetes,47MUT@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS2_k127_4111723_4	1237149.C900_00628	9.278e-261	807.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS2_k127_4111723_49	1237149.C900_00629	2.07e-55	198.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,47PSK@768503|Cytophagia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS2_k127_4111723_30	1237149.C900_00630	1.228e-95	315.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,47MZS@768503|Cytophagia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS2_k127_4111723_9	1237149.C900_00631	2.074e-176	556.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS2_k127_4111723_63	1237149.C900_00633	1.826e-30	120.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,47S89@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS2_k127_4111723_62	1121904.ARBP01000002_gene7070	1.142e-35	141.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,47QNM@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
CMS2_k127_4111723_14	1237149.C900_00636	1.16e-140	453.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS2_k127_4111723_33	866536.Belba_2437	2.285e-91	307.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,47KWT@768503|Cytophagia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS2_k127_4111723_8	1237149.C900_00638	1.002e-178	570.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,47JTX@768503|Cytophagia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS2_k127_4111723_26	504472.Slin_0324	1.66e-99	334.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,47K6J@768503|Cytophagia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS2_k127_4111723_15	1237149.C900_00640	1.937e-135	435.0	COG1357@1|root,COG1357@2|Bacteria,4NY1Q@976|Bacteroidetes,47WKP@768503|Cytophagia	976|Bacteroidetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS2_k127_4111723_40	1237149.C900_00641	4.466e-68	234.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,47P7N@768503|Cytophagia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS2_k127_4111723_48	1237149.C900_00642	2.56e-57	201.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,47Q95@768503|Cytophagia	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS2_k127_4111723_13	1237149.C900_00643	6.003e-146	470.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,47K3D@768503|Cytophagia	976|Bacteroidetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS2_k127_4111723_7	1237149.C900_00644	1.281e-212	674.0	COG2937@1|root,COG2937@2|Bacteria,4NK5H@976|Bacteroidetes,47M20@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_4111723_72	1121904.ARBP01000003_gene6360	3.066e-09	66.0	2DGY2@1|root,2ZXQQ@2|Bacteria,4P8NT@976|Bacteroidetes,47WGD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111723_5	926556.Echvi_2793	2.279e-250	803.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,47KMB@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS2_k127_4111723_17	1123276.KB893251_gene3657	2.371e-132	442.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,47T9R@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_4111723_44	1122176.KB903548_gene1193	6.301e-63	222.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS2_k127_4111723_31	1237149.C900_01781	1.02e-94	316.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111723_2	1237149.C900_03459	0.0	1018.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
CMS2_k127_4111723_25	1237149.C900_03460	2.974e-103	341.0	COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,47MUR@768503|Cytophagia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS2_k127_4111723_21	1237149.C900_03461	2.803e-112	372.0	COG0392@1|root,COG0392@2|Bacteria,4NIWG@976|Bacteroidetes,47MPB@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS2_k127_4111723_52	926556.Echvi_1762	1.951e-50	185.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,47P6S@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS2_k127_4111723_53	643867.Ftrac_1918	1.139e-49	189.0	COG4856@1|root,COG4856@2|Bacteria,4NK5K@976|Bacteroidetes,47K4N@768503|Cytophagia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111723_64	1237149.C900_03470	1.804e-29	120.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,47R3A@768503|Cytophagia	976|Bacteroidetes	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS2_k127_4111723_45	1237149.C900_03471	3.287e-59	209.0	2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,47XYM@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS2_k127_4111723_61	1237149.C900_03472	8.244e-36	138.0	COG4980@1|root,COG4980@2|Bacteria,4NVHP@976|Bacteroidetes,47RXK@768503|Cytophagia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS2_k127_4111723_24	1237149.C900_03473	2.796e-105	353.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,47M4A@768503|Cytophagia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS2_k127_4111723_10	1237149.C900_03474	3.903e-167	533.0	COG0334@1|root,COG0334@2|Bacteria,4NF3I@976|Bacteroidetes,47MHP@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_4111723_3	1237149.C900_03476	2.084e-272	849.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS2_k127_4111723_11	1237149.C900_04914	1.374e-164	522.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47JEN@768503|Cytophagia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS2_k127_4111723_23	1237149.C900_02726	9.628e-108	356.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,47KI4@768503|Cytophagia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS2_k127_4111723_36	1237149.C900_02727	2.347e-77	265.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,47PRP@768503|Cytophagia	976|Bacteroidetes	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS2_k127_4111723_19	1237149.C900_02728	9.268e-130	417.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,47KEX@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	pcbD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS2_k127_4111723_46	1237149.C900_02730	1.324e-58	208.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,47S9N@768503|Cytophagia	976|Bacteroidetes	S	PFAM Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS2_k127_4111723_55	985255.APHJ01000035_gene51	8.803e-48	176.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1I1X6@117743|Flavobacteriia,2P6QZ@244698|Gillisia	976|Bacteroidetes	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS2_k127_4111723_22	926549.KI421517_gene396	6.698e-109	356.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,47K7U@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS2_k127_4111723_1	1239962.C943_01596	0.0	1027.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS2_k127_4111723_50	1237149.C900_01745	3.554e-55	196.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes,47Q9W@768503|Cytophagia	976|Bacteroidetes	O	Chaperonin 10 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
CMS2_k127_4111723_71	1237149.C900_01746	1.978e-11	67.0	2ECIG@1|root,336GN@2|Bacteria,4NX5X@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111723_35	1123057.P872_18130	3.807e-79	269.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,47JX7@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
CMS2_k127_4111723_41	1237149.C900_02207	4.746e-67	235.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,47NQ9@768503|Cytophagia	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_4111723_42	866536.Belba_2289	2.805e-65	226.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,47PE3@768503|Cytophagia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS2_k127_4111723_20	1237149.C900_02205	2.251e-126	410.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,47PSA@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
CMS2_k127_4111723_37	1237149.C900_02204	1.526e-75	263.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,47NP8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111723_60	269798.CHU_2664	1.333e-40	155.0	COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS2_k127_4111723_57	1237149.C900_02202	2.38e-43	162.0	COG2050@1|root,COG2050@2|Bacteria,4NT7R@976|Bacteroidetes,47RY0@768503|Cytophagia	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS2_k127_4111723_59	1237149.C900_02200	7.852e-41	155.0	COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47S5T@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS2_k127_4111723_16	1237149.C900_05514	1.205e-133	435.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS2_k127_4111723_51	1434325.AZQN01000004_gene1899	9.788e-51	194.0	2BQ9X@1|root,32J4V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4111723_65	929562.Emtol_3691	1.372e-23	104.0	COG2010@1|root,COG2010@2|Bacteria,4NTWV@976|Bacteroidetes,47REP@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c, class I	aniA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_4111723_39	1237149.C900_00531	1.058e-72	251.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS2_k127_4111723_47	1305737.JAFX01000001_gene103	7.227e-58	206.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,47PXS@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS2_k127_4111723_58	641524.ADICYQ_2103	4.502e-42	164.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia	976|Bacteroidetes	S	beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
CMS2_k127_4111723_28	643867.Ftrac_3380	1.67e-97	323.0	COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes,47N83@768503|Cytophagia	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_4111723_18	1048983.EL17_14735	2.431e-131	425.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,47JRY@768503|Cytophagia	976|Bacteroidetes	E	PFAM Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
CMS2_k127_4111723_29	1313301.AUGC01000007_gene524	2.364e-96	326.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes	976|Bacteroidetes	P	K transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS2_k127_4111997_2	313606.M23134_02869	3.197e-31	123.0	COG3565@1|root,COG3565@2|Bacteria,4NNHW@976|Bacteroidetes,47PTX@768503|Cytophagia	976|Bacteroidetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_4111997_0	926559.JoomaDRAFT_3399	4.397e-211	668.0	COG3039@1|root,COG3039@2|Bacteria,4PKH0@976|Bacteroidetes,1HXKB@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS2_k127_4111997_1	1492737.FEM08_18800	1.501e-56	203.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia,2NTT8@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS2_k127_4134826_20	313606.M23134_01293	1.244e-108	383.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
CMS2_k127_4134826_22	643867.Ftrac_1238	1.006e-99	334.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_4134826_33	886377.Murru_2174	1.419e-47	198.0	COG2931@1|root,COG5384@1|root,COG2931@2|Bacteria,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes,1IJ9Q@117743|Flavobacteriia	976|Bacteroidetes	JQ	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,TSP_3
CMS2_k127_4134826_2	643867.Ftrac_1239	6.199e-271	889.0	COG2911@1|root,COG4932@1|root,COG5644@1|root,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
CMS2_k127_4134826_27	1237149.C900_00021	2.266e-67	232.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,47PPX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
CMS2_k127_4134826_23	1392498.JQLH01000001_gene2605	1.607e-94	316.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1HZ1U@117743|Flavobacteriia,2PGJP@252356|Maribacter	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS2_k127_4134826_9	926556.Echvi_1513	9.628e-176	557.0	COG1082@1|root,COG1082@2|Bacteria,4NG75@976|Bacteroidetes,47JT2@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS2_k127_4134826_42	927658.AJUM01000037_gene1853	2.701e-12	67.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,2FV24@200643|Bacteroidia,3XKFT@558415|Marinilabiliaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_4134826_41	385682.AFSL01000092_gene738	2.438e-12	66.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,2FV24@200643|Bacteroidia,3XKFT@558415|Marinilabiliaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_4134826_11	1124780.ANNU01000067_gene428	1.833e-173	564.0	COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,47KWV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
CMS2_k127_4134826_6	1237149.C900_02227	1.684e-210	666.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,47MUN@768503|Cytophagia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS2_k127_4134826_3	1237149.C900_02228	9.872e-233	725.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,47K6I@768503|Cytophagia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS2_k127_4134826_28	1237149.C900_02229	1.508e-66	235.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,47PU4@768503|Cytophagia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
CMS2_k127_4134826_14	643867.Ftrac_3294	1.321e-150	489.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,47KY0@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_4134826_15	1237149.C900_02231	3.285e-134	437.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS2_k127_4134826_12	1237149.C900_02232	3.791e-173	550.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,47K3R@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS2_k127_4134826_17	866536.Belba_1651	2.06e-131	432.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,47KTX@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS2_k127_4134826_4	1237149.C900_02234	2.681e-214	670.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,47KEP@768503|Cytophagia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS2_k127_4134826_8	1237149.C900_02235	4.291e-199	631.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_4134826_0	1237149.C900_02236	6.335e-283	884.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,47K6U@768503|Cytophagia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
CMS2_k127_4134826_36	1237149.C900_02237	3.387e-34	134.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,47R7E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4134826_18	153721.MYP_4213	1.664e-118	387.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,47JJ6@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS2_k127_4134826_32	1237149.C900_02239	4.101e-58	205.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,47Q53@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS2_k127_4134826_10	1237149.C900_02247	1.641e-175	557.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,47KX3@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS2_k127_4134826_34	1392498.JQLH01000001_gene3623	1.54e-47	176.0	29VE2@1|root,30GUS@2|Bacteria,4NP29@976|Bacteroidetes,1I29M@117743|Flavobacteriia,2PIGW@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4134826_29	1120951.AUBG01000014_gene3181	1.24e-64	226.0	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,1I2VH@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Pentapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
CMS2_k127_4134826_30	1237149.C900_02248	1.22e-60	215.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,47QB1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS2_k127_4134826_21	1237149.C900_02249	7.956e-105	342.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,47KRI@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS2_k127_4134826_19	1237149.C900_02250	1.096e-110	360.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,47P80@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS2_k127_4134826_25	1237149.C900_02251	1.38e-79	273.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,47TVG@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
CMS2_k127_4134826_13	643867.Ftrac_1553	4.28e-170	544.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,47ND4@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
CMS2_k127_4134826_7	1237149.C900_02255	5.6e-207	651.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,47M23@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
CMS2_k127_4134826_26	926556.Echvi_2010	9.05e-68	237.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,47K5Q@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS2_k127_4134826_1	643867.Ftrac_3270	1.717e-272	855.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,47JBG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS2_k127_4134826_16	531844.FIC_01750	1.311e-133	428.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,1HZIX@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_4134826_31	926549.KI421517_gene2074	1.259e-58	213.0	2EHJH@1|root,336RS@2|Bacteria,4NX01@976|Bacteroidetes,47SDR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4134826_5	1123278.KB893623_gene3429	3.104e-214	677.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_4134826_35	1305737.JAFX01000001_gene1146	1.63e-41	161.0	2DBKF@1|root,2Z9SZ@2|Bacteria,4NFPX@976|Bacteroidetes,47SSY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4134826_40	313595.P700755_003718	9.455e-16	85.0	COG3656@1|root,COG4704@1|root,COG3656@2|Bacteria,COG4704@2|Bacteria,4PHV8@976|Bacteroidetes,1IG0Z@117743|Flavobacteriia,4C4H2@83612|Psychroflexus	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4134826_37	391598.FBBAL38_11469	3.611e-31	126.0	COG4704@1|root,COG5295@1|root,COG4704@2|Bacteria,COG5295@2|Bacteria,4NTMP@976|Bacteroidetes,1I4NQ@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
CMS2_k127_4134826_43	186497.PF1591	4.249e-05	47.0	COG2362@1|root,arCOG04080@2157|Archaea,2XVFH@28890|Euryarchaeota,243NH@183968|Thermococci	183968|Thermococci	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
CMS2_k127_4134826_24	1408473.JHXO01000009_gene3392	2.151e-88	296.0	COG4030@1|root,COG4030@2|Bacteria,4NHV9@976|Bacteroidetes,2FNZY@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS2_k127_4138972_22	760192.Halhy_1113	3.835e-66	237.0	COG0657@1|root,COG0657@2|Bacteria,4NNWF@976|Bacteroidetes	976|Bacteroidetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
CMS2_k127_4138972_2	1237149.C900_05420	2.176e-295	913.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
CMS2_k127_4138972_25	929703.KE386491_gene3229	1.725e-56	204.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,47Q1Q@768503|Cytophagia	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS2_k127_4138972_26	1237149.C900_05422	5.185e-49	177.0	COG0640@1|root,COG0640@2|Bacteria,4NRN0@976|Bacteroidetes,47QVI@768503|Cytophagia	976|Bacteroidetes	K	arsR family	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS2_k127_4138972_3	1123057.P872_02175	3.797e-231	725.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,47KMG@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_4138972_21	1237149.C900_05423	2.611e-69	241.0	2BBSK@1|root,325AS@2|Bacteria,4NR2Q@976|Bacteroidetes,47JP3@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_4138972_32	643867.Ftrac_2445	1.975e-40	153.0	COG0071@1|root,COG0071@2|Bacteria,4NSJB@976|Bacteroidetes,47R4W@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS2_k127_4138972_10	1237149.C900_03794	3.321e-147	479.0	COG1914@1|root,COG1914@2|Bacteria,4NEG8@976|Bacteroidetes,47TDM@768503|Cytophagia	976|Bacteroidetes	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS2_k127_4138972_23	1322246.BN4_12789	1.492e-65	246.0	COG0642@1|root,COG0715@1|root,COG0715@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	fgrL	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,PocR,Response_reg,Y_Y_Y
CMS2_k127_4138972_28	926549.KI421517_gene2180	5.434e-46	173.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,47QGN@768503|Cytophagia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_4138972_13	468059.AUHA01000003_gene1568	5.354e-93	321.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_4138972_14	1123276.KB893246_gene923	1.545e-90	311.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47MFI@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS2_k127_4138972_0	929556.Solca_1727	0.0	1228.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS2_k127_4138972_17	643867.Ftrac_2259	6.46e-79	273.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,47KA1@768503|Cytophagia	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS2_k127_4138972_16	926562.Oweho_2434	1.411e-86	316.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1I8HX@117743|Flavobacteriia,2PAB4@246874|Cryomorphaceae	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
CMS2_k127_4138972_7	1237149.C900_00911	1.694e-162	516.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,47JMK@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_4138972_15	926559.JoomaDRAFT_0304	3.557e-87	301.0	COG2265@1|root,COG2265@2|Bacteria,4PKBS@976|Bacteroidetes,1HXP3@117743|Flavobacteriia	976|Bacteroidetes	J	(SAM)-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95,Methyltransf_15
CMS2_k127_4138972_9	1237149.C900_04887	5.35e-149	477.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,47KFN@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS2_k127_4138972_8	1237149.C900_03224	1.948e-153	498.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,47NX6@768503|Cytophagia	976|Bacteroidetes	M	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
CMS2_k127_4138972_20	1124780.ANNU01000049_gene2195	4.962e-71	246.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,47PA2@768503|Cytophagia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS2_k127_4138972_18	1121859.KB890739_gene2108	7.127e-73	248.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,47PXE@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS2_k127_4138972_24	926549.KI421517_gene154	5.104e-58	211.0	COG3386@1|root,COG3386@2|Bacteria,4NK29@976|Bacteroidetes,47PWH@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
CMS2_k127_4138972_34	643867.Ftrac_0563	2.584e-17	87.0	2DS6V@1|root,33ETJ@2|Bacteria,4NY48@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4138972_11	1237149.C900_00543	1.469e-123	419.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CHU_C,DUF285,LRR_5,PKD,Peptidase_M43,fn3
CMS2_k127_4138972_31	880070.Cycma_0365	9.189e-42	156.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CMS2_k127_4138972_29	272562.CA_C0632	1.005e-44	171.0	COG0637@1|root,COG0637@2|Bacteria,1V1NW@1239|Firmicutes,24G37@186801|Clostridia,36IF1@31979|Clostridiaceae	186801|Clostridia	J	subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,HAD_2
CMS2_k127_4138972_6	313606.M23134_03383	4.887e-186	591.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,47K6M@768503|Cytophagia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS2_k127_4138972_12	1237149.C900_03492	9.331e-96	327.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
CMS2_k127_4138972_33	1237149.C900_03491	8.457e-28	118.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GerE,Mor,Response_reg,Y_Y_Y
CMS2_k127_4138972_1	1121904.ARBP01000001_gene5544	1e-322	1005.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47JCM@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CMS2_k127_4138972_4	1237149.C900_01787	1.132e-192	610.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS2_k127_4138972_19	1121898.Q766_14480	3.377e-71	249.0	COG3741@1|root,COG3741@2|Bacteria,4NIN9@976|Bacteroidetes,1I0JT@117743|Flavobacteriia,2NY9I@237|Flavobacterium	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS2_k127_4138972_27	1237149.C900_03495	4.494e-46	169.0	COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,47QK8@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
CMS2_k127_4138972_30	929562.Emtol_2321	1.084e-43	165.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CMS2_k127_4138972_5	1237149.C900_00764	3.03e-189	599.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CMS2_k127_4157497_15	1121930.AQXG01000011_gene1764	1.482e-87	294.0	COG0454@1|root,COG0454@2|Bacteria,4PKZU@976|Bacteroidetes	976|Bacteroidetes	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_4157497_2	1237149.C900_04841	4.87e-176	559.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,47JNE@768503|Cytophagia	976|Bacteroidetes	E	argininosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS2_k127_4157497_9	742766.HMPREF9455_02087	9.148e-122	398.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,2FMWZ@200643|Bacteroidia,22WTC@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_4157497_16	1443665.JACA01000033_gene1772	5.432e-84	286.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1HX1Q@117743|Flavobacteriia,2YIZ4@290174|Aquimarina	976|Bacteroidetes	E	Pyrroline-5-carboxylate reductase dimerisation	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS2_k127_4157497_4	999419.HMPREF1077_00504	3.527e-156	500.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,2FNR5@200643|Bacteroidia,22VXR@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_4157497_7	929703.KE386491_gene377	2.209e-126	411.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,47JPH@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS2_k127_4157497_17	1122176.KB903565_gene3394	6.695e-77	265.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1IPBE@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS2_k127_4157497_8	742767.HMPREF9456_00470	9.859e-125	408.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,2FN2Z@200643|Bacteroidia,22X74@171551|Porphyromonadaceae	976|Bacteroidetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_4157497_1	743722.Sph21_1042	5.28e-181	576.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
CMS2_k127_4157497_13	886377.Murru_1834	1.082e-93	315.0	28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,1HYRY@117743|Flavobacteriia	976|Bacteroidetes	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
CMS2_k127_4157497_6	1150600.ADIARSV_0897	9.225e-137	459.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	hyfB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12137,ko:K15828	-	-	-	-	ko00000,ko01000	-	-	iB21_1397.B21_02538,iECBD_1354.ECBD_1002,iECB_1328.ECB_02573,iECD_1391.ECD_02573,iECED1_1282.ECED1_3174,iECO111_1330.ECO111_3443,iECO26_1355.ECO26_3788,iECP_1309.ECP_2686,iEKO11_1354.EKO11_1252,iEcHS_1320.EcHS_A2859,iLF82_1304.LF82_1065,iNRG857_1313.NRG857_13330	Proton_antipo_M,Proton_antipo_N
CMS2_k127_4157497_14	1150600.ADIARSV_0898	3.501e-93	314.0	COG0650@1|root,COG0650@2|Bacteria,4P2YM@976|Bacteroidetes	976|Bacteroidetes	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
CMS2_k127_4157497_19	742725.HMPREF9450_01607	1.23e-34	140.0	COG4237@1|root,COG4237@2|Bacteria,4P642@976|Bacteroidetes,2G25J@200643|Bacteroidia,22UED@171550|Rikenellaceae	976|Bacteroidetes	C	Hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS2_k127_4157497_10	1150600.ADIARSV_0900	3.945e-118	395.0	COG0651@1|root,COG0651@2|Bacteria,4P1B6@976|Bacteroidetes	976|Bacteroidetes	CP	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
CMS2_k127_4157497_5	742725.HMPREF9450_01609	2.006e-139	459.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,4P295@976|Bacteroidetes,2G1PF@200643|Bacteroidia,22U63@171550|Rikenellaceae	976|Bacteroidetes	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
CMS2_k127_4157497_12	1150600.ADIARSV_3159	2.7e-98	327.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	ehrS	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2596	Fer4,Fer4_15,Fer4_7,Oxidored_q6
CMS2_k127_4157497_0	1121904.ARBP01000039_gene2522	4.64e-217	695.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47KTW@768503|Cytophagia	976|Bacteroidetes	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
CMS2_k127_4157497_22	1108849.XP_002568093.1	1.373e-06	57.0	COG0288@1|root,KOG1578@2759|Eukaryota,3A8NY@33154|Opisthokonta,3P7IJ@4751|Fungi,3QZJ1@4890|Ascomycota,20NE3@147545|Eurotiomycetes,3SDDS@5042|Eurotiales	4751|Fungi	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS2_k127_4157497_3	926556.Echvi_4027	4.854e-166	533.0	2BVKK@1|root,2Z8PC@2|Bacteria,4NF9X@976|Bacteroidetes,47KVJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CMS2_k127_4157497_18	760192.Halhy_4056	1.668e-59	209.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1ITHC@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
CMS2_k127_4157497_21	313606.M23134_00047	2.668e-13	72.0	COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes,47RZY@768503|Cytophagia	976|Bacteroidetes	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS2_k127_4157497_20	313606.M23134_06302	7.394e-24	106.0	COG0822@1|root,COG0822@2|Bacteria,4P667@976|Bacteroidetes	976|Bacteroidetes	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS2_k127_4157497_11	215803.DB30_6995	1.804e-113	379.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS2_k127_4157497_23	1123035.ARLA01000007_gene630	1.84e-05	48.0	COG0249@1|root,COG0249@2|Bacteria,4NGEA@976|Bacteroidetes,1HYPR@117743|Flavobacteriia	976|Bacteroidetes	L	MutS domain V	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
CMS2_k127_4160963_3	1121007.AUML01000006_gene3130	2.911e-25	106.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
CMS2_k127_4160963_2	324925.Ppha_0058	2.161e-37	143.0	2DBNW@1|root,32TXT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MqsR_toxin
CMS2_k127_4160963_1	324925.Ppha_0057	3.96e-106	353.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	ps301	-	-	-	-	-	-	-	-	-	-	-	DUF4065,HTH_3,MqsA_antitoxin
CMS2_k127_4160963_0	1121875.KB907550_gene737	5e-324	1002.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IIHD@117743|Flavobacteriia	976|Bacteroidetes	S	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS2_k127_4205282_13	313606.M23134_00345	1.591e-20	96.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,47R3Q@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM bacillithiol system protein YtxJ	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
CMS2_k127_4205282_8	1237149.C900_01773	3.49e-71	248.0	28MPU@1|root,2ZAYW@2|Bacteria,4NRQD@976|Bacteroidetes,47NJK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4205282_3	388413.ALPR1_04583	2.181e-168	531.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS2_k127_4205282_11	1237149.C900_04492	6.091e-38	146.0	2E4SF@1|root,32ZKW@2|Bacteria,4NV4G@976|Bacteroidetes,47RXS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
CMS2_k127_4205282_5	1237149.C900_04493	8.664e-110	361.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,47JJ8@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS2_k127_4205282_9	1380384.JADN01000003_gene743	3.346e-59	212.0	COG0500@1|root,COG2226@2|Bacteria,4NJ84@976|Bacteroidetes,1HXEK@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,NodS
CMS2_k127_4205282_10	926559.JoomaDRAFT_0762	4.483e-38	147.0	2DBIE@1|root,32TXH@2|Bacteria,4NSJE@976|Bacteroidetes,1I4ME@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4205282_6	1237149.C900_03096	4.267e-103	348.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,47JRK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
CMS2_k127_4205282_0	1237149.C900_03097	0.0	1992.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
CMS2_k127_4205282_4	1237149.C900_03098	1.388e-154	500.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,47NRA@768503|Cytophagia	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS2_k127_4205282_7	1237149.C900_03099	1.133e-100	331.0	COG0745@1|root,COG0745@2|Bacteria,4NGI5@976|Bacteroidetes,47NIM@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_4205282_1	1237149.C900_04576	0.0	1487.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS2_k127_4205282_2	886377.Murru_0073	1.301e-180	579.0	COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,1I137@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_4205282_12	1288963.ADIS_4862	1.207e-23	100.0	COG1426@1|root,COG1426@2|Bacteria,4PMNR@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_4205773_1	1121373.KB903632_gene553	2.421e-22	113.0	COG2911@1|root,COG2911@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
CMS2_k127_4205773_0	1237149.C900_03603	1.864e-219	698.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,47KE5@768503|Cytophagia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CMS2_k127_4221639_6	880070.Cycma_3321	8.376e-18	83.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,4NM1M@976|Bacteroidetes,47PMA@768503|Cytophagia	976|Bacteroidetes	K	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_M78
CMS2_k127_4221639_0	1250278.JQNQ01000001_gene1705	0.0	1671.0	COG0610@1|root,COG0610@2|Bacteria,4NFJ8@976|Bacteroidetes,1HXHQ@117743|Flavobacteriia	976|Bacteroidetes	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CMS2_k127_4221639_3	313595.P700755_000895	6.908e-112	374.0	COG0732@1|root,COG0732@2|Bacteria,4PIIH@976|Bacteroidetes,1INFW@117743|Flavobacteriia,4C4H6@83612|Psychroflexus	976|Bacteroidetes	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
CMS2_k127_4221639_2	616991.JPOO01000001_gene2762	8.197e-142	458.0	COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,4NHNX@976|Bacteroidetes,1I1A8@117743|Flavobacteriia	976|Bacteroidetes	K	Plasmid maintenance system antidote protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
CMS2_k127_4221639_4	616991.JPOO01000001_gene2761	6.651e-36	139.0	COG3549@1|root,COG3549@2|Bacteria,4NT4R@976|Bacteroidetes,1I6MK@117743|Flavobacteriia	976|Bacteroidetes	S	Plasmid maintenance system killer	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
CMS2_k127_4221639_1	1123234.AUKI01000013_gene1664	4.847e-316	970.0	COG0286@1|root,COG0286@2|Bacteria,4NG0E@976|Bacteroidetes,1HYSD@117743|Flavobacteriia	976|Bacteroidetes	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CMS2_k127_4221639_7	714943.Mucpa_6121	1.045e-09	67.0	2EPY9@1|root,33HIV@2|Bacteria,4NYZF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4221639_5	1115515.EV102420_14_01440	5.153e-35	140.0	2ABSC@1|root,3118T@2|Bacteria,1RDBX@1224|Proteobacteria,1S5RV@1236|Gammaproteobacteria,3XQYS@561|Escherichia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4235605_2	1121288.AULL01000013_gene1816	4.394e-12	80.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia,3ZNZ0@59732|Chryseobacterium	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
CMS2_k127_4235605_0	1237149.C900_03408	2.949e-46	192.0	COG2755@1|root,COG3209@1|root,COG4733@1|root,COG2755@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,4NJGD@976|Bacteroidetes,47VZA@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS2_k127_4235605_1	1296415.JACC01000003_gene3016	5.92e-24	119.0	COG3595@1|root,COG5498@1|root,COG3595@2|Bacteria,COG5498@2|Bacteria	2|Bacteria	M	chitin catabolic process	-	-	3.2.1.136	ko:K02358,ko:K15924	-	-	-	-	ko00000,ko01000,ko03012,ko03029,ko04147	-	GH5	-	CBM_6,Cellulase,DUF4097,F5_F8_type_C,PA14,RicinB_lectin_2
CMS2_k127_4245373_0	269799.Gmet_3341	1.666e-14	78.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2WQ5S@28221|Deltaproteobacteria,43VCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
CMS2_k127_4253437_5	926559.JoomaDRAFT_3155	6.593e-96	316.0	COG1082@1|root,COG1082@2|Bacteria,4NFKF@976|Bacteroidetes,1HZU8@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_4253437_4	1123248.KB893359_gene2154	1.368e-115	378.0	COG0726@1|root,COG0726@2|Bacteria,4NJK7@976|Bacteroidetes	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS2_k127_4253437_3	1122621.ATZA01000024_gene2145	1.198e-123	418.0	COG3284@1|root,COG3284@2|Bacteria	2|Bacteria	KQ	transcription factor binding	acoR	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GerE,HATPase_c,HTH_3,HTH_8,HisKA,PAS,PAS_4,PAS_8,PAS_9,Sigma54_activat
CMS2_k127_4253437_1	235909.GK0710	4.481e-160	509.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli,1WG18@129337|Geobacillus	91061|Bacilli	C	Transketolase, thiamine diphosphate binding domain	acoA	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
CMS2_k127_4253437_2	1382304.JNIL01000001_gene1518	1.664e-150	482.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_4253437_6	1382304.JNIL01000001_gene1517	3.63e-14	75.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HD9Z@91061|Bacilli,279NA@186823|Alicyclobacillaceae	91061|Bacilli	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_4253437_0	880070.Cycma_1880	0.0	1061.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia	976|Bacteroidetes	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
CMS2_k127_4253437_7	272559.BF9343_4107	0.0004789	52.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,4AM5H@815|Bacteroidaceae	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CMS2_k127_4262387_1	1237149.C900_01251	2.419e-13	78.0	COG3170@1|root,COG3170@2|Bacteria,4PNNG@976|Bacteroidetes,47SUJ@768503|Cytophagia	976|Bacteroidetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4262387_0	1124780.ANNU01000075_gene827	5.063e-153	492.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,47KSQ@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS2_k127_4262387_2	485918.Cpin_2165	5.049e-09	69.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,4NIJY@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
CMS2_k127_4299604_23	643867.Ftrac_0853	2.375e-10	72.0	COG3292@1|root,COG4372@1|root,COG3292@2|Bacteria,COG4372@2|Bacteria,4NGX0@976|Bacteroidetes,47NDW@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_8,PAS_9,Reg_prop,Y_Y_Y
CMS2_k127_4299604_4	1454007.JAUG01000001_gene3682	2.125e-187	609.0	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,1IQC3@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
CMS2_k127_4299604_21	1237149.C900_00540	1.284e-20	95.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS2_k127_4299604_13	1237149.C900_04630	2.649e-68	240.0	COG4843@1|root,COG4843@2|Bacteria,4NRH5@976|Bacteroidetes,47PXG@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
CMS2_k127_4299604_11	1237149.C900_00622	1.336e-108	358.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,47KHJ@768503|Cytophagia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS2_k127_4299604_8	1121904.ARBP01000002_gene6932	7.226e-158	503.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,47KPH@768503|Cytophagia	976|Bacteroidetes	E	Homocysteine S-methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS2_k127_4299604_1	1123278.KB893603_gene1864	0.0	1187.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,47K8Q@768503|Cytophagia	976|Bacteroidetes	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS2_k127_4299604_6	1237149.C900_01372	2.593e-176	556.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,47KQ7@768503|Cytophagia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS2_k127_4299604_12	1185876.BN8_04807	3.13e-94	316.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,47KB5@768503|Cytophagia	976|Bacteroidetes	E	Isopropylmalate homocitrate citramalate synthase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS2_k127_4299604_14	1237149.C900_01380	1.415e-66	232.0	COG0457@1|root,COG0457@2|Bacteria,4NUXH@976|Bacteroidetes,47XIV@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_8
CMS2_k127_4299604_5	1237149.C900_04385	1.456e-183	577.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,47J9X@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_4299604_2	1237149.C900_04383	1.161e-215	685.0	COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,47KBE@768503|Cytophagia	976|Bacteroidetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TPR_16,TPR_2,TPR_8
CMS2_k127_4299604_19	1237149.C900_04382	2.96e-29	117.0	COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,47RWN@768503|Cytophagia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
CMS2_k127_4299604_10	929562.Emtol_2961	3.317e-111	369.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,47K2G@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS2_k127_4299604_18	1237149.C900_04380	1.088e-38	147.0	COG0718@1|root,COG0718@2|Bacteria,4NQ37@976|Bacteroidetes,47R3V@768503|Cytophagia	976|Bacteroidetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS2_k127_4299604_9	1237149.C900_04378	4.828e-122	413.0	COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS2_k127_4299604_3	1121889.AUDM01000013_gene1856	1.64e-191	609.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2NSUV@237|Flavobacterium	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CMS2_k127_4299604_7	1239962.C943_03810	3.094e-172	551.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,47KPD@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS2_k127_4299604_16	643867.Ftrac_0764	3.73e-48	177.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,47QNZ@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS2_k127_4299604_15	1237149.C900_04701	2.371e-53	195.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_4299604_20	1237149.C900_04850	3.034e-25	111.0	COG2062@1|root,COG2062@2|Bacteria,4PMDV@976|Bacteroidetes,47Y2D@768503|Cytophagia	976|Bacteroidetes	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS2_k127_4299604_22	1237149.C900_00635	9.785e-14	76.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4299604_0	1237149.C900_02615	0.0	1541.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_4299604_17	198467.NP92_00070	2.624e-47	179.0	2DBYB@1|root,2ZBUC@2|Bacteria,1V738@1239|Firmicutes,4HFT2@91061|Bacilli,21VN7@150247|Anoxybacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_50	1237149.C900_03740	1.706e-56	210.0	28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,47RCK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_45	1121904.ARBP01000002_gene7200	4.114e-66	232.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,47M1W@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
CMS2_k127_4314240_40	1237149.C900_01794	2.456e-83	292.0	COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47MUM@768503|Cytophagia	976|Bacteroidetes	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS2_k127_4314240_5	1237149.C900_01793	0.0	1097.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes,47NP5@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS2_k127_4314240_41	643867.Ftrac_3316	4.001e-76	265.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,47JAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_4314240_44	1237149.C900_00705	3.747e-72	252.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,47PBZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
CMS2_k127_4314240_14	1120965.AUBV01000004_gene668	7.724e-208	662.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,47KZU@768503|Cytophagia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS2_k127_4314240_63	1237149.C900_00707	3.954e-09	62.0	2E1YR@1|root,32X7B@2|Bacteria,4NUBX@976|Bacteroidetes,47R5A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_22	1237149.C900_00708	2.29e-163	546.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47K15@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CMS2_k127_4314240_15	1237149.C900_00709	1.997e-196	617.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47JT9@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS2_k127_4314240_37	1237149.C900_01531	1.846e-94	317.0	COG2849@1|root,COG2849@2|Bacteria,4NK1X@976|Bacteroidetes,47NFY@768503|Cytophagia	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_57	117187.FVEG_08411T0	2.223e-24	119.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NW9Q@4751|Fungi,3QJDH@4890|Ascomycota,218YM@147550|Sordariomycetes,3TPUM@5125|Hypocreales,1FX25@110618|Nectriaceae	4751|Fungi	M	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,HET,NACHT
CMS2_k127_4314240_10	643867.Ftrac_2141	3.581e-250	780.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,47K1F@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS2_k127_4314240_61	1121481.AUAS01000008_gene3048	2.655e-13	77.0	29KB5@1|root,3078F@2|Bacteria,4NNX1@976|Bacteroidetes,47Q3E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_13	1237149.C900_04623	2.273e-221	701.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,47M5S@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS2_k127_4314240_32	1237149.C900_04621	3.128e-130	424.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,47N45@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	ygjT	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CMS2_k127_4314240_25	1279009.ADICEAN_00015	6.198e-157	511.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NTM4@976|Bacteroidetes,47RWF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_20	1123057.P872_05525	4.697e-181	571.0	COG2267@1|root,COG2267@2|Bacteria,4NFIJ@976|Bacteroidetes,47NQX@768503|Cytophagia	976|Bacteroidetes	I	Releases the N-terminal proline from various substrates	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS2_k127_4314240_30	153721.MYP_1451	1.278e-145	465.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,47JDE@768503|Cytophagia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS2_k127_4314240_43	1237149.C900_04001	1.401e-74	258.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47JI7@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_4314240_23	1237149.C900_03999	1.877e-159	539.0	COG0457@1|root,COG0457@2|Bacteria,4NGQ7@976|Bacteroidetes,47KHQ@768503|Cytophagia	976|Bacteroidetes	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
CMS2_k127_4314240_26	926556.Echvi_0091	3.399e-156	500.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,47MN7@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS2_k127_4314240_8	643867.Ftrac_1875	1.894e-274	865.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,47TVT@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
CMS2_k127_4314240_27	1237149.C900_01522	2.762e-155	523.0	COG3292@1|root,COG3292@2|Bacteria,4NNTX@976|Bacteroidetes,47U09@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_Y_Y
CMS2_k127_4314240_7	1237149.C900_03488	1.551e-300	932.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,47JAZ@768503|Cytophagia	976|Bacteroidetes	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
CMS2_k127_4314240_19	643867.Ftrac_3307	3.996e-183	578.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,47K13@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS2_k127_4314240_11	1237149.C900_00714	6.682e-235	734.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
CMS2_k127_4314240_28	1237149.C900_04627	8.394e-147	486.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
CMS2_k127_4314240_21	1237149.C900_04628	1.676e-165	541.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
CMS2_k127_4314240_18	1408813.AYMG01000011_gene818	3.673e-185	588.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS2_k127_4314240_3	761193.Runsl_2530	0.0	1215.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47YE9@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CMS2_k127_4314240_29	1123277.KB893172_gene845	4.026e-146	475.0	COG3193@1|root,COG3193@2|Bacteria,4NGTI@976|Bacteroidetes	976|Bacteroidetes	S	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_4314240_51	504472.Slin_4220	2.706e-56	205.0	2CE3R@1|root,33DMZ@2|Bacteria,4NZHH@976|Bacteroidetes,47UN3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_56	504472.Slin_4219	3.786e-29	122.0	2F8BT@1|root,340QV@2|Bacteria,4P400@976|Bacteroidetes,47VM1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_12	504472.Slin_4218	1.819e-225	722.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47NXA@768503|Cytophagia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3
CMS2_k127_4314240_47	643867.Ftrac_2655	6.132e-63	229.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,47M4P@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
CMS2_k127_4314240_31	880070.Cycma_2500	1.98e-130	425.0	COG0667@1|root,COG0667@2|Bacteria,4NF06@976|Bacteroidetes,47K7K@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_4314240_52	1124780.ANNU01000049_gene2210	3.534e-55	200.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
CMS2_k127_4314240_49	1237149.C900_03754	1.508e-57	203.0	2EFJ6@1|root,339BJ@2|Bacteria,4NUYU@976|Bacteroidetes,47VMH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_35	1237149.C900_03755	1.481e-106	353.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_1	1237149.C900_03756	0.0	1455.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,TerB
CMS2_k127_4314240_46	1237149.C900_03757	7.779e-65	222.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,47R7M@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
CMS2_k127_4314240_42	1279009.ADICEAN_01286	4.905e-75	256.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,47Q0I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_2	1237149.C900_03759	0.0	1334.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4NIXZ@976|Bacteroidetes,47MCW@768503|Cytophagia	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,PAS,PAS_4,PAS_9,SpoIIE
CMS2_k127_4314240_62	1124780.ANNU01000002_gene1489	1.567e-10	71.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
CMS2_k127_4314240_38	1279009.ADICEAN_01289	2.035e-86	290.0	COG2201@1|root,COG2201@2|Bacteria,4NNR3@976|Bacteroidetes,47PAB@768503|Cytophagia	976|Bacteroidetes	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
CMS2_k127_4314240_33	1237149.C900_03762	3.968e-123	399.0	COG1352@1|root,COG1352@2|Bacteria,4NFDS@976|Bacteroidetes,47JV5@768503|Cytophagia	976|Bacteroidetes	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS2_k127_4314240_17	1237149.C900_03765	1.064e-187	596.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47MT4@768503|Cytophagia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS2_k127_4314240_24	1237149.C900_03148	1.642e-157	508.0	COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,47KD3@768503|Cytophagia	976|Bacteroidetes	F	Deoxyguanosinetriphosphate triphosphohydrolase-like protein	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS2_k127_4314240_6	1237149.C900_03147	0.0	1030.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS2_k127_4314240_0	1237149.C900_03146	0.0	1669.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CMS2_k127_4314240_39	1237149.C900_03145	2.33e-86	289.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS2_k127_4314240_59	643867.Ftrac_2522	2.133e-19	94.0	2928S@1|root,2ZPTC@2|Bacteria,4P8WI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_4	1237149.C900_02054	0.0	1097.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47YDB@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CMS2_k127_4314240_64	468059.AUHA01000003_gene1637	1.957e-06	55.0	2CDET@1|root,2ZBN1@2|Bacteria,4NN6D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_48	1237149.C900_03067	2.128e-58	213.0	28M39@1|root,2ZAHI@2|Bacteria,4NM3I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4314240_34	313603.FB2170_06925	1.719e-120	392.0	COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,1HX87@117743|Flavobacteriia,2PGRG@252356|Maribacter	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_4314240_16	929562.Emtol_1718	5.635e-191	598.0	COG5285@1|root,COG5285@2|Bacteria,4NG3B@976|Bacteroidetes,47N28@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS2_k127_4314240_9	313595.P700755_002794	6.643e-272	845.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HZ5E@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_4314240_36	1121481.AUAS01000013_gene4256	8.897e-97	323.0	COG1028@1|root,COG1028@2|Bacteria,4NGYV@976|Bacteroidetes,47N9Y@768503|Cytophagia	976|Bacteroidetes	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS2_k127_4314240_53	143224.JQMD01000002_gene2710	2.531e-53	192.0	COG2318@1|root,COG2318@2|Bacteria,4NPTK@976|Bacteroidetes	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS2_k127_4314240_54	1250278.JQNQ01000001_gene1684	1.273e-43	166.0	COG1075@1|root,COG1075@2|Bacteria,4NIEZ@976|Bacteroidetes,1I0TU@117743|Flavobacteriia	976|Bacteroidetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
CMS2_k127_4314240_55	575590.HMPREF0156_00411	8.752e-31	124.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_4340848_0	641524.ADICYQ_5574	4.53e-227	705.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47MDV@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS2_k127_4340848_1	641524.ADICYQ_5575	2.015e-85	286.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CMS2_k127_4340848_3	1469557.JSWF01000019_gene299	2.497e-33	130.0	COG3609@1|root,COG3609@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
CMS2_k127_4340848_5	1227272.HMPREF1556_00984	2.312e-09	59.0	COG3943@1|root,COG3943@2|Bacteria,4NEGN@976|Bacteroidetes,2FM81@200643|Bacteroidia	976|Bacteroidetes	S	Toxin-antitoxin system, toxin component, Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
CMS2_k127_4340848_6	1123278.KB893450_gene6227	5.159e-05	46.0	COG4680@1|root,COG4680@2|Bacteria,4NSID@976|Bacteroidetes,47V89@768503|Cytophagia	976|Bacteroidetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HigB_toxin
CMS2_k127_4340848_4	886379.AEWI01000007_gene833	4.425e-30	121.0	COG5499@1|root,COG5499@2|Bacteria,4NSZ7@976|Bacteroidetes,2FXVN@200643|Bacteroidia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_26,HTH_3
CMS2_k127_4340848_2	755732.Fluta_0918	3.236e-40	168.0	COG3210@1|root,COG3210@2|Bacteria,4P1PQ@976|Bacteroidetes,1ICP0@117743|Flavobacteriia,2PBF7@246874|Cryomorphaceae	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4354263_4	1499967.BAYZ01000185_gene4530	1.808e-104	368.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
CMS2_k127_4354263_6	927677.ALVU02000001_gene1450	1.138e-46	187.0	COG5002@1|root,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,dCache_1
CMS2_k127_4354263_10	1048983.EL17_06970	6.189e-12	78.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47N6B@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_4354263_1	313603.FB2170_10424	2.667e-202	640.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia,2PGP8@252356|Maribacter	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_4354263_0	485917.Phep_2315	2.213e-284	882.0	COG0129@1|root,COG0129@2|Bacteria,4NEKY@976|Bacteroidetes,1IQEN@117747|Sphingobacteriia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
CMS2_k127_4354263_3	1123248.KB893338_gene2315	1.914e-110	362.0	COG1028@1|root,COG1028@2|Bacteria,4NF64@976|Bacteroidetes,1IQVT@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_4354263_7	1223410.KN050846_gene133	1.882e-21	101.0	2FA13@1|root,342A6@2|Bacteria,4P4HY@976|Bacteroidetes,1I9KT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4354263_2	1233951.IO90_14180	4.852e-177	572.0	COG0326@1|root,COG0326@2|Bacteria,4PKTZ@976|Bacteroidetes	976|Bacteroidetes	O	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
CMS2_k127_4354263_5	1121287.AUMU01000018_gene2521	1.944e-83	296.0	2AKI0@1|root,31BA0@2|Bacteria,4P988@976|Bacteroidetes,1IB6W@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4354521_2	1123371.ATXH01000006_gene816	0.0003703	43.0	COG1943@1|root,COG1943@2|Bacteria,2GI5R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_4354521_1	521674.Plim_1219	3.46e-09	61.0	2EJ1R@1|root,33CSX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4354521_0	857087.Metme_1952	2.763e-182	583.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1XGZ9@135618|Methylococcales	1236|Gammaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
CMS2_k127_4386457_12	655815.ZPR_0151	1.919e-06	51.0	COG2827@1|root,COG2827@2|Bacteria,4NW73@976|Bacteroidetes,1I5Z9@117743|Flavobacteriia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS2_k127_4386457_10	1237149.C900_00677	1.398e-22	100.0	COG3668@1|root,COG3668@2|Bacteria,4NUJP@976|Bacteroidetes	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CMS2_k127_4386457_3	313603.FB2170_02270	2.408e-178	562.0	COG0667@1|root,COG0667@2|Bacteria,4NHA1@976|Bacteroidetes,1HZQF@117743|Flavobacteriia,2PG5R@252356|Maribacter	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_4386457_7	1408433.JHXV01000004_gene3425	1.381e-64	227.0	COG1309@1|root,COG1309@2|Bacteria,4NTWF@976|Bacteroidetes,1I1HH@117743|Flavobacteriia,2PBTQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Bacterial transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
CMS2_k127_4386457_5	992406.RIA_1950	9.107e-101	340.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia	976|Bacteroidetes	CH	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS2_k127_4386457_0	1392498.JQLH01000001_gene2549	2.702e-286	893.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia,2PGPF@252356|Maribacter	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_4386457_11	1121875.KB907550_gene737	1.867e-17	84.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IIHD@117743|Flavobacteriia	976|Bacteroidetes	S	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS2_k127_4386457_4	1237149.C900_04877	8.937e-117	383.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47KF6@768503|Cytophagia	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_4386457_6	1185876.BN8_06692	1.011e-76	263.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,47KPQ@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS2_k127_4386457_2	1237149.C900_04875	1.667e-190	610.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia	976|Bacteroidetes	N	ABC transporter substrate-binding component GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS2_k127_4386457_8	1237149.C900_04874	1.877e-39	159.0	2E7J5@1|root,3321E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS2_k127_4386457_1	1237149.C900_04873	1.999e-191	602.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,47M1J@768503|Cytophagia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS2_k127_4392095_18	643867.Ftrac_0474	1.344e-114	378.0	COG0604@1|root,COG0604@2|Bacteria,4NF0Z@976|Bacteroidetes,47XCM@768503|Cytophagia	976|Bacteroidetes	C	COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS2_k127_4392095_7	1237149.C900_02822	1.76e-231	723.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47K0E@768503|Cytophagia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS2_k127_4392095_9	1124780.ANNU01000052_gene3584	4.982e-206	651.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,47K2Z@768503|Cytophagia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_4392095_0	1237149.C900_02826	0.0	1389.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS2_k127_4392095_25	1124780.ANNU01000052_gene3582	2.939e-61	218.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,47PR5@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS2_k127_4392095_28	1237149.C900_02828	9.561e-44	165.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,47QUB@768503|Cytophagia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS2_k127_4392095_20	1288963.ADIS_2649	6.491e-105	344.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,47MGG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS2_k127_4392095_27	1124780.ANNU01000052_gene3579	5.882e-51	183.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,47QAS@768503|Cytophagia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS2_k127_4392095_14	1237149.C900_00475	7.498e-141	451.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,47JX2@768503|Cytophagia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS2_k127_4392095_5	1237149.C900_00476	1.139e-240	768.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_4392095_12	880070.Cycma_0784	1.188e-148	477.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,47K90@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS2_k127_4392095_19	1237149.C900_01093	4.47e-111	365.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,47JJ3@768503|Cytophagia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
CMS2_k127_4392095_4	1237149.C900_01092	1.42e-270	840.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47JYJ@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS2_k127_4392095_24	1237149.C900_01090	3.407e-68	242.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,47MMF@768503|Cytophagia	976|Bacteroidetes	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS2_k127_4392095_22	1237149.C900_01089	1.079e-92	314.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,47M2P@768503|Cytophagia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CMS2_k127_4392095_1	1237149.C900_01088	6.375e-316	994.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,47JIS@768503|Cytophagia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4392095_2	1237149.C900_01087	1.121e-310	958.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,47M2W@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
CMS2_k127_4392095_31	1121373.KB903663_gene1230	2.202e-19	104.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	4.2.2.20,4.2.2.21	ko:K08961	-	-	-	-	ko00000,ko01000	-	-	-	CHU_C,Calx-beta,Lyase_8,Lyase_catalyt,PA14,SdrD_B
CMS2_k127_4392095_23	1237149.C900_01086	1.397e-84	311.0	COG3266@1|root,COG3291@1|root,COG3266@2|Bacteria,COG3291@2|Bacteria,4NUXN@976|Bacteroidetes,47S6U@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_4392095_16	1237149.C900_01085	9.513e-121	396.0	COG4772@1|root,COG4772@2|Bacteria,4NPH0@976|Bacteroidetes,47Q2J@768503|Cytophagia	976|Bacteroidetes	P	Pfam:DUF3308	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_4392095_6	1237149.C900_01084	4.75e-233	740.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_4392095_13	1237149.C900_01083	1.675e-141	459.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,47KMP@768503|Cytophagia	976|Bacteroidetes	E	PFAM Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
CMS2_k127_4392095_15	1120966.AUBU01000003_gene1693	8.323e-134	435.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes	976|Bacteroidetes	E	3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	aroF	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
CMS2_k127_4392095_21	153721.MYP_1441	3.142e-101	340.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,47JBE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS2_k127_4392095_17	1124780.ANNU01000017_gene1909	2.89e-120	398.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,47K1U@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS2_k127_4392095_10	1237149.C900_01074	2.516e-193	606.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,47MIG@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS2_k127_4392095_3	1313301.AUGC01000001_gene1411	1.963e-271	843.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS2_k127_4392095_11	1121904.ARBP01000012_gene1276	3.701e-160	511.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47KBZ@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
CMS2_k127_4392095_29	1124780.ANNU01000072_gene1066	8.694e-25	110.0	2DNFQ@1|root,32X9Z@2|Bacteria,4PNNB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4392095_30	1120966.AUBU01000002_gene1965	6.439e-24	103.0	COG2919@1|root,COG2919@2|Bacteria,4P9WW@976|Bacteroidetes,47S83@768503|Cytophagia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CMS2_k127_4392095_8	1237149.C900_01066	2.742e-231	720.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS2_k127_4392095_26	1239962.C943_00482	2.805e-58	203.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,47KT4@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS2_k127_4404872_4	1239962.C943_00313	1.815e-175	569.0	COG0362@1|root,COG3265@1|root,COG0362@2|Bacteria,COG3265@2|Bacteria,4NG05@976|Bacteroidetes,47NDJ@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2,SKI
CMS2_k127_4404872_0	926549.KI421517_gene3707	1.86e-280	893.0	COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4NKVN@976|Bacteroidetes,47MDT@768503|Cytophagia	976|Bacteroidetes	CG	Carbohydrate binding module (family 6)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
CMS2_k127_4404872_12	487796.Flav2ADRAFT_1680	2.625e-106	351.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,1HX7K@117743|Flavobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_4404872_8	595494.Tola_2884	5.24e-137	446.0	COG1312@1|root,COG1312@2|Bacteria,1MWYD@1224|Proteobacteria,1RR0Q@1236|Gammaproteobacteria,1Y5M7@135624|Aeromonadales	135624|Aeromonadales	G	D-mannonate dehydratase (UxuA)	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS2_k127_4404872_3	1380600.AUYN01000009_gene1169	2.93e-189	602.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1HYH2@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_4404872_6	487796.Flav2ADRAFT_1677	3.634e-139	454.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1HZMA@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_4404872_1	1239962.C943_00386	4.66e-232	743.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_4404872_7	1121930.AQXG01000001_gene1102	3.013e-137	463.0	COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_4404872_20	1506583.JQJY01000004_gene2642	1.885e-68	235.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I20A@117743|Flavobacteriia,2NUX6@237|Flavobacterium	976|Bacteroidetes	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS2_k127_4404872_24	313595.P700755_002821	3.147e-45	167.0	COG2402@1|root,COG2402@2|Bacteria,4NNQV@976|Bacteroidetes,1I1FT@117743|Flavobacteriia,4C4CU@83612|Psychroflexus	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
CMS2_k127_4404872_30	641524.ADICYQ_2579	4.608e-18	87.0	2DMNP@1|root,32SQ4@2|Bacteria,4NT2A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4404872_18	315730.BcerKBAB4_1882	2.817e-85	291.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,1ZD8D@1386|Bacillus	91061|Bacilli	S	Oxidoreductase	ycsN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_4404872_11	857087.Metme_3602	7.803e-111	371.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,1XDYZ@135618|Methylococcales	135618|Methylococcales	G	Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
CMS2_k127_4404872_21	504487.JCM19302_2426	3.064e-61	218.0	COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1I0H0@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS2_k127_4404872_28	1168289.AJKI01000001_gene3601	1.587e-25	108.0	2C85M@1|root,31BVK@2|Bacteria,4PK2A@976|Bacteroidetes,2G1M4@200643|Bacteroidia,3XKWF@558415|Marinilabiliaceae	976|Bacteroidetes	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS2_k127_4404872_23	1408433.JHXV01000006_gene2769	4.939e-46	170.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia,2PB36@246874|Cryomorphaceae	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS2_k127_4404872_22	1197477.IA57_10575	1.742e-60	217.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1HY3J@117743|Flavobacteriia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
CMS2_k127_4404872_13	1121904.ARBP01000015_gene210	5.957e-104	355.0	28ID4@1|root,2Z8FC@2|Bacteria,4NFYZ@976|Bacteroidetes,47NAT@768503|Cytophagia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4404872_17	1517682.HW49_11275	9.804e-87	292.0	COG1131@1|root,COG1131@2|Bacteria,4NDV7@976|Bacteroidetes,2FN84@200643|Bacteroidia,22XIR@171551|Porphyromonadaceae	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_4404872_10	1237149.C900_03167	7.343e-130	424.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS2_k127_4404872_2	1237149.C900_01521	9.25e-217	680.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47MQD@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009986,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_4404872_25	1237149.C900_00366	8.689e-40	154.0	COG1238@1|root,COG1238@2|Bacteria,4NMW6@976|Bacteroidetes,47VDA@768503|Cytophagia	976|Bacteroidetes	I	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS2_k127_4404872_29	643867.Ftrac_3247	9.877e-25	108.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS2_k127_4404872_16	1121904.ARBP01000001_gene5400	8.863e-88	299.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,DUF1080
CMS2_k127_4404872_27	1239962.C943_04388	3.771e-31	124.0	COG5662@1|root,COG5662@2|Bacteria,4P3CI@976|Bacteroidetes,47UWT@768503|Cytophagia	976|Bacteroidetes	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS2_k127_4404872_5	1178825.ALIH01000010_gene373	1.054e-163	523.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,1HYXX@117743|Flavobacteriia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340,3.2.1.197	ko:K20885,ko:K21065	-	-	R11397,R11398,R11544	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS2_k127_4404872_15	1237149.C900_00402	1.325e-92	314.0	COG0596@1|root,COG0596@2|Bacteria,4PNPN@976|Bacteroidetes,47XAU@768503|Cytophagia	976|Bacteroidetes	S	Ndr family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS2_k127_4404872_26	1538644.KO02_12010	7.295e-35	138.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes	976|Bacteroidetes	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS2_k127_4404872_14	1237149.C900_05555	2.856e-103	340.0	COG4894@1|root,COG4894@2|Bacteria,4NK2I@976|Bacteroidetes,47VBX@768503|Cytophagia	976|Bacteroidetes	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	Scramblase
CMS2_k127_4404872_31	1286632.P278_27940	8.675e-07	60.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HXMP@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_4404872_9	204669.Acid345_3040	2.262e-132	437.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS2_k127_4404872_19	411154.GFO_2906	1.326e-78	290.0	COG4932@1|root,COG4932@2|Bacteria,4NK3C@976|Bacteroidetes,1I0WF@117743|Flavobacteriia	976|Bacteroidetes	M	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4431170_7	1408473.JHXO01000013_gene561	1.554e-35	139.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FX61@200643|Bacteroidia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS2_k127_4431170_0	643867.Ftrac_1996	0.0	1122.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS2_k127_4431170_5	926556.Echvi_1181	1.583e-54	198.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,47P8Z@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS2_k127_4431170_4	926549.KI421517_gene165	2.022e-63	222.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,47PE9@768503|Cytophagia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS2_k127_4431170_8	1121930.AQXG01000009_gene270	1.134e-33	135.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS2_k127_4431170_6	926556.Echvi_0993	1.467e-46	179.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47KIJ@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
CMS2_k127_4431170_2	1237149.C900_03206	2.033e-130	424.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,47JVC@768503|Cytophagia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS2_k127_4431170_3	1089547.KB913013_gene2887	5.715e-69	235.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,47PQ3@768503|Cytophagia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS2_k127_4431170_9	1463881.KL591019_gene3457	6.748e-12	77.0	COG0438@1|root,COG0438@2|Bacteria,2GYA2@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS2_k127_4431170_1	926551.KB900738_gene133	1.118e-138	450.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia,1EQCG@1016|Capnocytophaga	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS2_k127_4446528_2	1121904.ARBP01000008_gene3424	2.48e-128	421.0	COG1506@1|root,COG1506@2|Bacteria,4PNN5@976|Bacteroidetes,47YBM@768503|Cytophagia	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS2_k127_4446528_4	616991.JPOO01000001_gene3530	3.141e-55	203.0	COG2197@1|root,COG2197@2|Bacteria,4NQZ6@976|Bacteroidetes	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3
CMS2_k127_4446528_0	643867.Ftrac_0533	1.268e-295	913.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47JG7@768503|Cytophagia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_4446528_7	522306.CAP2UW1_3533	3.08e-24	104.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	DUF1186,SEC-C,UPF0149
CMS2_k127_4446528_1	1122605.KB893643_gene709	2.645e-182	588.0	COG3934@1|root,COG3934@2|Bacteria,4NF13@976|Bacteroidetes,1IRK6@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CMS2_k127_4446528_10	1121007.AUML01000042_gene3411	7.611e-06	51.0	COG0251@1|root,COG0251@2|Bacteria,4NR3V@976|Bacteroidetes,1I36T@117743|Flavobacteriia,2YJG3@290174|Aquimarina	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS2_k127_4446528_3	1461693.ATO10_09273	3.439e-112	385.0	COG0682@1|root,COG0682@2|Bacteria,1R7B3@1224|Proteobacteria	1224|Proteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT,PAP2_3,PEMT
CMS2_k127_4446528_6	696748.ASU2_02250	1.475e-24	113.0	2E03A@1|root,32VS4@2|Bacteria,1N4NZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4446528_12	2880.D7FT46	0.0001952	52.0	COG1562@1|root,KOG1459@2759|Eukaryota	2759|Eukaryota	I	farnesyl-diphosphate farnesyltransferase activity	PSY	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009536,GO:0009975,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016119,GO:0016120,GO:0016740,GO:0016765,GO:0016767,GO:0016853,GO:0016860,GO:0042214,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045436,GO:0046148,GO:0046246,GO:0046905,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99,4.1.2.13,5.5.1.19	ko:K01623,ko:K02291,ko:K17841	ko00010,ko00030,ko00051,ko00680,ko00710,ko00906,ko01062,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map00906,map01062,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00097,M00165,M00167	R01068,R01070,R01829,R02065,R02568,R03824,R04218,R05341,R07270,R10177,R10508	RC00362,RC00438,RC00439,RC00603,RC00604,RC01004,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006,ko03036,ko04131,ko04147	-	-	-	SQS_PSY
CMS2_k127_4446528_5	472759.Nhal_2817	8.075e-42	162.0	COG1272@1|root,COG1272@2|Bacteria	2|Bacteria	K	protein, Hemolysin III	yplQ	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS2_k127_4446528_11	755732.Fluta_1871	0.0001196	56.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes	976|Bacteroidetes	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS2_k127_4446528_8	880071.Fleli_1577	2.219e-15	91.0	COG3386@1|root,COG3386@2|Bacteria,4PP7E@976|Bacteroidetes,47YII@768503|Cytophagia	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS2_k127_4446528_9	929556.Solca_0738	7.294e-10	73.0	COG3291@1|root,COG3291@2|Bacteria,4PHZU@976|Bacteroidetes,1IWHN@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_4457534_41	313606.M23134_03762	8.917e-53	200.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
CMS2_k127_4457534_31	1380600.AUYN01000001_gene2927	8.429e-86	295.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1HXU5@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS2_k127_4457534_1	1237149.C900_01447	4.914e-296	923.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,47KMU@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS2_k127_4457534_9	1408473.JHXO01000006_gene1129	2.732e-190	618.0	COG3211@1|root,COG4935@1|root,COG3211@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,2G16U@200643|Bacteroidia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
CMS2_k127_4457534_25	1237149.C900_00456	8.339e-108	353.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CMS2_k127_4457534_32	1288963.ADIS_3136	3.125e-84	282.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,47Q0N@768503|Cytophagia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CMS2_k127_4457534_11	1237149.C900_02512	1.272e-183	584.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47JWT@768503|Cytophagia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS2_k127_4457534_37	643867.Ftrac_0913	1.764e-64	223.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,47QD1@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
CMS2_k127_4457534_44	1121904.ARBP01000003_gene6457	9.989e-46	167.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,47QBC@768503|Cytophagia	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS2_k127_4457534_39	1237149.C900_05659	2.73e-59	208.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,47Q7A@768503|Cytophagia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
CMS2_k127_4457534_12	1237149.C900_05660	2.227e-177	564.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,47JNS@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS2_k127_4457534_30	1123057.P872_10400	1.115e-86	301.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,47K0R@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS2_k127_4457534_19	1288963.ADIS_2068	2.619e-135	434.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,47N88@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS2_k127_4457534_2	1237149.C900_05664	1.865e-282	871.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,47JZJ@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS2_k127_4457534_35	1237149.C900_05665	3.889e-69	237.0	COG1522@1|root,COG1522@2|Bacteria,4NHG9@976|Bacteroidetes,47PXD@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix ASNC type	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS2_k127_4457534_6	1237149.C900_04780	1.699e-250	783.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47K1E@768503|Cytophagia	976|Bacteroidetes	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS2_k127_4457534_49	1237149.C900_04776	7.727e-33	132.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4457534_27	313606.M23134_03769	3.195e-102	340.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,47MC7@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS2_k127_4457534_50	1237149.C900_02552	8.277e-32	130.0	2ENX1@1|root,33GHZ@2|Bacteria,4NXFU@976|Bacteroidetes,47WQI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4457534_4	1237149.C900_02551	7.598e-262	822.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,47KR4@768503|Cytophagia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS2_k127_4457534_42	1237149.C900_01408	5.454e-51	195.0	COG0484@1|root,COG0484@2|Bacteria,4NPWD@976|Bacteroidetes,47SGB@768503|Cytophagia	976|Bacteroidetes	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF805,DnaJ,TPR_16
CMS2_k127_4457534_23	1237149.C900_01409	1.129e-112	374.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,47M2T@768503|Cytophagia	976|Bacteroidetes	LU	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
CMS2_k127_4457534_52	926549.KI421517_gene3599	1.004e-28	118.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,47R35@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS2_k127_4457534_29	1124780.ANNU01000032_gene1251	1.003e-87	300.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_4457534_33	1237149.C900_01417	1.978e-71	252.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_4457534_0	1239962.C943_01965	0.0	1140.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,47KKH@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS2_k127_4457534_22	1237149.C900_01420	8.162e-116	384.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
CMS2_k127_4457534_47	1296416.JACB01000005_gene204	3.771e-38	143.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1HYG1@117743|Flavobacteriia,2YHUT@290174|Aquimarina	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_4457534_51	1313301.AUGC01000001_gene1816	4.621e-29	118.0	COG0640@1|root,COG0640@2|Bacteria,4NSHB@976|Bacteroidetes	976|Bacteroidetes	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS2_k127_4457534_46	1235803.C825_00211	3.105e-42	161.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
CMS2_k127_4457534_24	1237149.C900_02612	1.928e-112	370.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,47NTZ@768503|Cytophagia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS2_k127_4457534_26	1124780.ANNU01000024_gene3038	2.482e-102	345.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,47MTG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_4457534_38	643867.Ftrac_1013	1.239e-60	215.0	COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,47Q2B@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS2_k127_4457534_15	1124780.ANNU01000024_gene3040	8.943e-152	490.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes,47KV0@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
CMS2_k127_4457534_16	1237149.C900_02380	3.78e-144	471.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia	976|Bacteroidetes	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
CMS2_k127_4457534_5	1237149.C900_02381	1.109e-258	804.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_4457534_40	1237149.C900_02382	3.673e-58	204.0	COG0784@1|root,COG0784@2|Bacteria,4NRC9@976|Bacteroidetes,47QC7@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_4457534_7	1237149.C900_02383	2.68e-224	703.0	28KRY@1|root,2ZA9E@2|Bacteria,4NI1H@976|Bacteroidetes,47N4R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4457534_20	1237149.C900_00090	3.711e-126	408.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,47M4X@768503|Cytophagia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS2_k127_4457534_21	1237149.C900_00092	2.49e-121	394.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,47M3D@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS2_k127_4457534_43	1124780.ANNU01000043_gene336	2.513e-49	178.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,47Q9B@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS2_k127_4457534_34	880070.Cycma_2938	6.346e-71	241.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,47PQ7@768503|Cytophagia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS2_k127_4457534_36	1279009.ADICEAN_01448	2.629e-68	239.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,47KJC@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM pseudouridine synthase, RluA family	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS2_k127_4457534_13	643867.Ftrac_3711	5.519e-158	503.0	COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia	976|Bacteroidetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS2_k127_4457534_48	1237149.C900_02887	1.313e-34	137.0	COG1030@1|root,COG1030@2|Bacteria,4NW09@976|Bacteroidetes,47S4B@768503|Cytophagia	976|Bacteroidetes	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS2_k127_4457534_17	1237149.C900_02886	7.225e-143	478.0	COG0515@1|root,COG0515@2|Bacteria	1237149.C900_02886|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4457534_28	1124780.ANNU01000015_gene1995	3.802e-89	300.0	COG1028@1|root,COG1028@2|Bacteria,4NMH8@976|Bacteroidetes,47P21@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_4457534_53	1313421.JHBV01000039_gene2668	5.293e-25	113.0	COG0671@1|root,COG0671@2|Bacteria,4NR78@976|Bacteroidetes	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS2_k127_4457534_14	1237149.C900_05493	4.233e-154	493.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,47KHU@768503|Cytophagia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS2_k127_4457534_54	1237149.C900_05492	1.348e-09	65.0	2CH9X@1|root,33DG6@2|Bacteria,4NYSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4457534_18	643867.Ftrac_0939	8.262e-140	454.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS2_k127_4457534_8	1121373.KB903638_gene918	7.321e-220	698.0	COG0438@1|root,COG0438@2|Bacteria,4PKQN@976|Bacteroidetes,47K56@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycogen synthase	-	-	2.4.1.11	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3	-	Glycogen_syn
CMS2_k127_4457534_10	866536.Belba_3586	1.476e-189	603.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,47KIP@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
CMS2_k127_4457534_3	1336803.PHEL49_2629	6.431e-269	845.0	COG0457@1|root,COG3206@1|root,COG0457@2|Bacteria,COG3206@2|Bacteria,4NH33@976|Bacteroidetes,1HYMC@117743|Flavobacteriia,3VX4T@52959|Polaribacter	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_4457534_45	1237149.C900_05596	3.853e-45	170.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,47JBU@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS2_k127_4471341_9	1121904.ARBP01000013_gene400	2.147e-101	335.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,47SW9@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS2_k127_4471341_1	1122176.KB903587_gene4540	1.002e-178	568.0	COG4591@1|root,COG4591@2|Bacteria,4NJRI@976|Bacteroidetes	976|Bacteroidetes	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_4471341_2	1121904.ARBP01000013_gene398	3.42e-167	533.0	COG4591@1|root,COG4591@2|Bacteria,4NKUN@976|Bacteroidetes,47TP5@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CMS2_k127_4471341_7	1122176.KB903587_gene4542	2.425e-112	366.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IY1V@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_4471341_6	1121904.ARBP01000013_gene396	4.427e-136	443.0	28HAJ@1|root,2Z7MX@2|Bacteria,4NKQQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4471341_15	1122176.KB903587_gene4544	3.31e-49	182.0	COG1309@1|root,COG1309@2|Bacteria,4NU6H@976|Bacteroidetes	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_4471341_4	760192.Halhy_2757	2.808e-152	489.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1ISZC@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS2_k127_4471341_21	1166018.FAES_2628	9.586e-07	58.0	COG3266@1|root,COG3266@2|Bacteria,4NNQN@976|Bacteroidetes,47PZT@768503|Cytophagia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4471341_11	1124780.ANNU01000032_gene1245	6.842e-78	264.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,47P9H@768503|Cytophagia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS2_k127_4471341_8	1237149.C900_01201	6.461e-105	344.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,47P7V@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS2_k127_4471341_20	153721.MYP_1565	2.384e-07	63.0	2C4MF@1|root,300D5@2|Bacteria,4NPEA@976|Bacteroidetes,47RYT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4471341_18	1121373.KB903643_gene3617	3.652e-25	119.0	COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,47V9Y@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4471341_3	1121904.ARBP01000026_gene668	4.987e-159	515.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,47KCU@768503|Cytophagia	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4301
CMS2_k127_4471341_12	1237149.C900_03615	6.021e-77	265.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4471341_13	643867.Ftrac_1469	2.876e-59	208.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,47PV8@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
CMS2_k127_4471341_16	926549.KI421517_gene3630	2.515e-47	174.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS2_k127_4471341_5	1121904.ARBP01000016_gene5239	3.588e-149	485.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,47MVE@768503|Cytophagia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS2_k127_4471341_14	118173.KB235914_gene2162	1.98e-57	204.0	COG1443@1|root,COG1443@2|Bacteria,1GDFS@1117|Cyanobacteria	1117|Cyanobacteria	I	NUDIX domain	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
CMS2_k127_4471341_10	1089547.KB913013_gene2212	1.627e-89	303.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
CMS2_k127_4471341_0	313606.M23134_07221	1.619e-197	626.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS2_k127_4471341_17	1089547.KB913013_gene2210	1.17e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,47KPZ@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_4471341_19	525257.HMPREF0204_11871	2.801e-11	67.0	2DBB3@1|root,2Z85F@2|Bacteria,4NKCY@976|Bacteroidetes,1HZTC@117743|Flavobacteriia,3ZNK6@59732|Chryseobacterium	976|Bacteroidetes	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
CMS2_k127_4496532_3	1237149.C900_01139	3.818e-190	597.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,47K6D@768503|Cytophagia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS2_k127_4496532_7	1237149.C900_01140	1.166e-93	320.0	28NIY@1|root,2ZBK8@2|Bacteria,4NM7G@976|Bacteroidetes,47PEJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4496532_8	1237149.C900_01141	4.071e-84	290.0	COG4324@1|root,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia	976|Bacteroidetes	I	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
CMS2_k127_4496532_6	1189612.A33Q_0112	2.675e-94	314.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_4496532_5	1237149.C900_01144	1.435e-113	376.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,47JX1@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS2_k127_4496532_9	313595.P700755_002432	2.018e-64	241.0	2CW3Z@1|root,32SYZ@2|Bacteria,4NTGZ@976|Bacteroidetes,1I4XD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4496532_10	866536.Belba_0607	3.132e-57	203.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_4496532_1	1348583.ATLH01000023_gene670	1.985e-240	756.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia,1FA9X@104264|Cellulophaga	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS2_k127_4496532_15	313596.RB2501_04745	3.974e-05	51.0	2DBJ2@1|root,32TXJ@2|Bacteria,4NTRP@976|Bacteroidetes,1I43A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4496532_0	1408473.JHXO01000013_gene608	0.0	1633.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2G0EK@200643|Bacteroidia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS2_k127_4496532_12	1124780.ANNU01000033_gene1310	8.293e-43	172.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,47NKF@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_4496532_4	1408473.JHXO01000013_gene610	8.511e-150	494.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,2FMQN@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4
CMS2_k127_4496532_14	1121285.AUFK01000012_gene1914	8.78e-08	56.0	COG4244@1|root,COG4244@2|Bacteria,4NRDG@976|Bacteroidetes,1I8CZ@117743|Flavobacteriia,3ZTFW@59732|Chryseobacterium	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4496532_11	1124780.ANNU01000044_gene542	5.879e-50	192.0	COG5505@1|root,COG5505@2|Bacteria,4NPE1@976|Bacteroidetes,47V2U@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS2_k127_4496532_2	1124780.ANNU01000049_gene2171	4.247e-220	699.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47JCA@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS2_k127_4496532_13	1237149.C900_00507	1.737e-30	129.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4576693_17	163908.KB235896_gene1554	7.377e-25	106.0	COG1943@1|root,COG1943@2|Bacteria,1G5WC@1117|Cyanobacteria,1HNPX@1161|Nostocales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_4576693_14	641524.ADICYQ_2249	1.717e-35	141.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,47QWF@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS2_k127_4576693_4	1237149.C900_04727	3.603e-137	445.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,47JTZ@768503|Cytophagia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
CMS2_k127_4576693_10	1237149.C900_04726	9.006e-89	295.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
CMS2_k127_4576693_9	1454007.JAUG01000020_gene1601	4.866e-95	319.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS2_k127_4576693_6	1237149.C900_04724	1.348e-124	405.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,47JT6@768503|Cytophagia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
CMS2_k127_4576693_0	1237149.C900_00375	7.912e-266	825.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,47MCS@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS2_k127_4576693_12	1219065.VPR01S_07_01790	1.605e-57	209.0	COG1028@1|root,COG1028@2|Bacteria,1QWF5@1224|Proteobacteria,1T3XY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_4576693_13	1122179.KB890424_gene3600	6.24e-52	199.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Acetyltransf_6,Aminotran_1_2,FemAB_like
CMS2_k127_4576693_7	1122179.KB890424_gene3602	6.32e-108	363.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes	2|Bacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,KR,PP-binding,PS-DH
CMS2_k127_4576693_8	796940.HMPREF9628_00654	2.138e-99	342.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia,25SXJ@186804|Peptostreptococcaceae	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS2_k127_4576693_3	1107311.Q767_10525	3.14e-166	533.0	COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,1INE4@117743|Flavobacteriia,2NZ97@237|Flavobacterium	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS2_k127_4576693_11	880073.Calab_3790	4.725e-78	275.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_4576693_2	313603.FB2170_03955	2.87e-178	570.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia,2PHYR@252356|Maribacter	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
CMS2_k127_4576693_5	649349.Lbys_2686	1.668e-131	434.0	COG3385@1|root,COG3385@2|Bacteria,4P5DN@976|Bacteroidetes,47VRV@768503|Cytophagia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS2_k127_4576693_16	649349.Lbys_2685	6.394e-25	106.0	2CFGC@1|root,33FFI@2|Bacteria,4NZ32@976|Bacteroidetes,47WF6@768503|Cytophagia	976|Bacteroidetes	S	sptr putative	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4576693_18	1122621.ATZA01000060_gene1025	5.18e-13	72.0	COG1524@1|root,COG1524@2|Bacteria,4PP2Z@976|Bacteroidetes	976|Bacteroidetes	S	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ
CMS2_k127_4576693_1	643867.Ftrac_0241	3.825e-238	740.0	COG3550@1|root,COG3550@2|Bacteria,4NFYY@976|Bacteroidetes,47MNZ@768503|Cytophagia	976|Bacteroidetes	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
CMS2_k127_4576693_15	313595.P700755_000932	4.479e-25	107.0	COG1426@1|root,COG1426@2|Bacteria,4PM8V@976|Bacteroidetes,1I5EI@117743|Flavobacteriia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_4587380_24	1121481.AUAS01000018_gene468	8.024e-69	245.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,47KI0@768503|Cytophagia	976|Bacteroidetes	HP	ABC transporter	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS2_k127_4587380_17	1046627.BZARG_1447	1.416e-99	335.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,1HXH4@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS2_k127_4587380_18	1237149.C900_03808	1.308e-98	335.0	COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,47MZX@768503|Cytophagia	976|Bacteroidetes	P	PFAM periplasmic binding protein	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS2_k127_4587380_25	1123277.KB893173_gene1573	3.342e-67	240.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,47M9T@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS2_k127_4587380_8	1237149.C900_03797	6.51e-156	503.0	COG4252@1|root,COG4252@2|Bacteria,4NMM6@976|Bacteroidetes,47PFU@768503|Cytophagia	976|Bacteroidetes	T	CHASE2 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2
CMS2_k127_4587380_20	1237149.C900_03796	1.086e-92	313.0	2BHR8@1|root,32BUM@2|Bacteria,4NR4P@976|Bacteroidetes,47QNP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4587380_2	641524.ADICYQ_3274	0.0	1039.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,47P4T@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
CMS2_k127_4587380_9	761193.Runsl_3514	2.659e-153	487.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,47K03@768503|Cytophagia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
CMS2_k127_4587380_4	1237149.C900_00716	3.794e-217	680.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CMS2_k127_4587380_12	926556.Echvi_1587	2.986e-133	436.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,47KRS@768503|Cytophagia	976|Bacteroidetes	E	Alanine dehydrogenase PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS2_k127_4587380_40	761193.Runsl_1080	1.703e-12	69.0	2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4587380_5	1120966.AUBU01000012_gene28	7.512e-195	620.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS2_k127_4587380_39	1237149.C900_04482	1.889e-17	88.0	2EEHV@1|root,338BQ@2|Bacteria,4NWH5@976|Bacteroidetes,47SB4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4587380_30	1237149.C900_04481	9.85e-50	180.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,47QE4@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS2_k127_4587380_29	1237149.C900_04480	3.781e-53	194.0	COG1250@1|root,COG1250@2|Bacteria,4NWYY@976|Bacteroidetes,47VDX@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH
CMS2_k127_4587380_41	1313301.AUGC01000001_gene1623	3.995e-09	69.0	28J4T@1|root,2Z90P@2|Bacteria,4NHUC@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
CMS2_k127_4587380_10	1237149.C900_04466	9.211e-140	447.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,47KUD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
CMS2_k127_4587380_21	153721.MYP_2031	2.366e-81	279.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS2_k127_4587380_27	929556.Solca_3494	9.301e-55	194.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,1IT2H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS2_k127_4587380_14	1237149.C900_04463	4.106e-110	365.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,47JZY@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS2_k127_4587380_26	926549.KI421517_gene917	3.429e-58	206.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,47PFX@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
CMS2_k127_4587380_19	1237149.C900_04461	8.253e-94	312.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,47MH4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS2_k127_4587380_15	700598.Niako_6251	9.18e-102	339.0	COG1082@1|root,COG1082@2|Bacteria,4NJF7@976|Bacteroidetes,1ISEM@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_4587380_13	945713.IALB_2867	2.269e-132	435.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS2_k127_4587380_1	1237149.C900_00927	0.0	1040.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia	976|Bacteroidetes	E	Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS2_k127_4587380_23	1237149.C900_00926	4.002e-72	248.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,47MSF@768503|Cytophagia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS2_k127_4587380_32	926562.Oweho_3286	2.579e-49	182.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1I48G@117743|Flavobacteriia	976|Bacteroidetes	J	2',5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CMS2_k127_4587380_0	1237149.C900_02745	0.0	1310.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N
CMS2_k127_4587380_11	1237149.C900_02744	1.694e-135	442.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,47M0Q@768503|Cytophagia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
CMS2_k127_4587380_36	1237149.C900_02742	1.969e-34	135.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS2_k127_4587380_33	1237149.C900_02741	5.552e-48	189.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,47M3Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4587380_28	867902.Ornrh_0947	3.227e-54	193.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1I24B@117743|Flavobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
CMS2_k127_4587380_16	1237149.C900_02739	7.201e-100	332.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,47KG0@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS2_k127_4587380_3	1237149.C900_02738	6.832e-237	737.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS2_k127_4587380_34	376686.Fjoh_4204	4.01e-39	153.0	COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes,1I2S6@117743|Flavobacteriia,2NSZJ@237|Flavobacterium	976|Bacteroidetes	S	Molybdopterin-guanine dinucleotide biosynthesis protein MobA	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS2_k127_4587380_35	1286632.P278_06910	1.441e-34	141.0	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,1IJ06@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS2_k127_4587380_37	1336803.PHEL49_0572	1.432e-26	115.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,1I45Z@117743|Flavobacteriia,3VWRK@52959|Polaribacter	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
CMS2_k127_4587380_6	1237149.C900_03243	1.154e-185	586.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,47MD9@768503|Cytophagia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS2_k127_4587380_31	1237149.C900_03242	2.418e-49	181.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,47QCT@768503|Cytophagia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS2_k127_4587380_7	1124780.ANNU01000042_gene637	4.637e-164	522.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,47JCS@768503|Cytophagia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS2_k127_4587380_22	866536.Belba_0476	5.681e-77	261.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,47NHN@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
CMS2_k127_4651872_10	1239962.C943_01390	9.34e-144	466.0	COG1373@1|root,COG1373@2|Bacteria,4NE3E@976|Bacteroidetes,47P2P@768503|Cytophagia	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14
CMS2_k127_4651872_32	196627.cg2566	6.307e-08	67.0	COG3204@1|root,COG3204@2|Bacteria,2I94U@201174|Actinobacteria,22KFK@1653|Corynebacteriaceae	201174|Actinobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
CMS2_k127_4651872_1	1122176.KB903531_gene3073	1.549e-300	959.0	COG2312@1|root,COG2312@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
CMS2_k127_4651872_22	926556.Echvi_3630	1.968e-66	233.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,47PM4@768503|Cytophagia	976|Bacteroidetes	G	PFAM KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
CMS2_k127_4651872_13	926556.Echvi_3631	1.527e-119	392.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,47KKJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM PfkB	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS2_k127_4651872_16	1238184.CM001792_gene3021	1.317e-88	304.0	COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1U9RR@1239|Firmicutes,4IJY3@91061|Bacilli,23MD1@182709|Oceanobacillus	91061|Bacilli	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
CMS2_k127_4651872_29	1123037.AUDE01000009_gene1380	3.335e-25	113.0	2C73B@1|root,330Z7@2|Bacteria,4NMGE@976|Bacteroidetes,1I53Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4651872_21	1249997.JHZW01000003_gene2335	4.458e-67	233.0	COG2318@1|root,COG2318@2|Bacteria,4NRSP@976|Bacteroidetes	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CMS2_k127_4651872_4	1121859.KB890750_gene286	2.236e-237	747.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,47K7S@768503|Cytophagia	976|Bacteroidetes	G	PFAM D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
CMS2_k127_4651872_6	880070.Cycma_2706	5.402e-223	700.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,47KAP@768503|Cytophagia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
CMS2_k127_4651872_7	1121904.ARBP01000043_gene2119	2.767e-207	650.0	COG0738@1|root,COG0738@2|Bacteria,4NEB2@976|Bacteroidetes,47KY1@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_4651872_17	1121100.JCM6294_81	3.658e-78	271.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNAA@200643|Bacteroidia,4AKBQ@815|Bacteroidaceae	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
CMS2_k127_4651872_11	1123248.KB893326_gene1336	1.674e-139	448.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1IV4B@117747|Sphingobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS2_k127_4651872_18	504472.Slin_3963	3.041e-77	265.0	COG2159@1|root,COG2159@2|Bacteria,4NH6P@976|Bacteroidetes,47M0D@768503|Cytophagia	976|Bacteroidetes	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_4651872_5	452637.Oter_0062	4.64e-225	717.0	COG4993@1|root,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
CMS2_k127_4651872_2	926562.Oweho_0977	1.971e-285	883.0	COG1028@1|root,COG4221@1|root,COG1028@2|Bacteria,COG4221@2|Bacteria,4NFBX@976|Bacteroidetes,1HXN7@117743|Flavobacteriia,2PA78@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS2_k127_4651872_33	1249997.JHZW01000002_gene592	7.303e-05	52.0	COG0457@1|root,COG0457@2|Bacteria,4NJ3W@976|Bacteroidetes,1I05Q@117743|Flavobacteriia,2PG1H@252356|Maribacter	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CMS2_k127_4651872_26	574375.BAGA_18610	1.431e-36	142.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS2_k127_4651872_12	643867.Ftrac_0333	1.199e-138	447.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Succinylglutamate desuccinylase Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS2_k127_4651872_9	1121904.ARBP01000002_gene7255	1.181e-146	469.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,47KJX@768503|Cytophagia	976|Bacteroidetes	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
CMS2_k127_4651872_25	1121904.ARBP01000002_gene7254	3.564e-43	162.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS2_k127_4651872_19	388413.ALPR1_19333	7.766e-70	241.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47P9R@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS2_k127_4651872_23	1237149.C900_05318	1.283e-63	226.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47MTX@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS2_k127_4651872_24	1237149.C900_05317	5.341e-62	225.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS2_k127_4651872_27	1237149.C900_05315	7.626e-36	144.0	2C9AB@1|root,2ZB91@2|Bacteria,4NKQ3@976|Bacteroidetes,47M3Q@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4651872_8	1237149.C900_05314	2.887e-158	523.0	COG4206@1|root,COG4206@2|Bacteria,4NGBJ@976|Bacteroidetes,47J8T@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_4651872_31	641524.ADICYQ_1601	7.021e-15	83.0	2DQQ3@1|root,33818@2|Bacteria,4NVCN@976|Bacteroidetes,47VHM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4651872_14	1347342.BN863_14130	1.091e-113	371.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS2_k127_4651872_0	1517682.HW49_06575	0.0	1195.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,22W14@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS2_k127_4651872_15	925409.KI911562_gene1137	5.036e-101	334.0	COG2102@1|root,COG2102@2|Bacteria,4NFQ4@976|Bacteroidetes,1ISHV@117747|Sphingobacteriia	976|Bacteroidetes	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
CMS2_k127_4651872_28	926556.Echvi_3756	1.972e-31	126.0	2EAY8@1|root,334Z8@2|Bacteria,4NWBD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4651872_20	1237149.C900_03046	2.388e-69	251.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47NGK@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS2_k127_4651872_3	1237149.C900_03047	7.028e-249	790.0	COG4773@1|root,COG4773@2|Bacteria,4NI3Y@976|Bacteroidetes,47KSZ@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_4658616_5	1408473.JHXO01000012_gene358	2.832e-61	223.0	COG1820@1|root,COG1820@2|Bacteria,4NJ35@976|Bacteroidetes,2FMRP@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS2_k127_4658616_2	761193.Runsl_2608	1.741e-103	341.0	COG0363@1|root,COG0363@2|Bacteria,4NFCM@976|Bacteroidetes,47PHR@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
CMS2_k127_4658616_4	382464.ABSI01000010_gene3488	4.215e-76	276.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_4658616_0	1286632.P278_19450	1.238e-160	516.0	COG1073@1|root,COG1073@2|Bacteria,4NG6A@976|Bacteroidetes,1I062@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4658616_3	388413.ALPR1_14294	4.419e-93	329.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,47KZN@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_10,TPR_12,TPR_7,TPR_8
CMS2_k127_4658616_6	234267.Acid_5521	3.178e-15	79.0	COG0500@1|root,COG2226@2|Bacteria,3Y8V7@57723|Acidobacteria	57723|Acidobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4658616_1	1121396.KB893065_gene1612	7.941e-108	389.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2MNF7@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	WD40 repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_35,Pkinase,WD40
CMS2_k127_4669316_5	313628.LNTAR_01957	3.726e-71	251.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS2_k127_4669316_1	1121012.AUKX01000036_gene779	4.052e-146	472.0	COG3828@1|root,COG3828@2|Bacteria,4NJK6@976|Bacteroidetes,1I11T@117743|Flavobacteriia,23GTH@178469|Arenibacter	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS2_k127_4669316_2	530564.Psta_0703	1.062e-134	437.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_4669316_4	641524.ADICYQ_1329	1.934e-118	386.0	COG1082@1|root,COG1082@2|Bacteria,4NHGW@976|Bacteroidetes,47MTJ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS2_k127_4669316_3	143224.JQMD01000002_gene78	6.763e-123	400.0	COG1082@1|root,COG1082@2|Bacteria,4NHMP@976|Bacteroidetes,1I6H6@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS2_k127_4669316_0	504472.Slin_5004	0.0	1312.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NKGP@976|Bacteroidetes,47M97@768503|Cytophagia	976|Bacteroidetes	C	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_4796551_10	1121904.ARBP01000002_gene7111	3.741e-32	126.0	COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47MR5@768503|Cytophagia	976|Bacteroidetes	E	RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_4796551_1	616991.JPOO01000003_gene2111	3.827e-218	683.0	COG0673@1|root,COG0673@2|Bacteria,4NFFJ@976|Bacteroidetes,1HXQ4@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_4796551_6	1288963.ADIS_2849	6.337e-114	379.0	COG2133@1|root,COG2133@2|Bacteria,4PMM3@976|Bacteroidetes,47NGM@768503|Cytophagia	976|Bacteroidetes	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS2_k127_4796551_7	1434325.AZQN01000001_gene274	4.335e-110	363.0	COG1082@1|root,COG1082@2|Bacteria,4NI4H@976|Bacteroidetes,47MMY@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_4796551_9	1347342.BN863_30160	8.194e-45	168.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I28Y@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS2_k127_4796551_4	1121875.KB907550_gene854	4.047e-148	474.0	COG1638@1|root,COG1638@2|Bacteria,4NGV4@976|Bacteroidetes,1HZ02@117743|Flavobacteriia	976|Bacteroidetes	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS2_k127_4796551_8	1121875.KB907550_gene853	3.262e-56	199.0	COG3090@1|root,COG3090@2|Bacteria,4NNRW@976|Bacteroidetes,1I24H@117743|Flavobacteriia	976|Bacteroidetes	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS2_k127_4796551_2	1249997.JHZW01000002_gene133	2.024e-217	680.0	COG1593@1|root,COG1593@2|Bacteria,4NE5T@976|Bacteroidetes,1HX6G@117743|Flavobacteriia,2PG1G@252356|Maribacter	976|Bacteroidetes	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS2_k127_4796551_3	1178825.ALIH01000002_gene1120	3.465e-208	655.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CMS2_k127_4796551_5	926559.JoomaDRAFT_2666	1.196e-114	373.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1HWN3@117743|Flavobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_4796551_0	1392498.JQLH01000001_gene1637	1.22e-317	989.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1HZ97@117743|Flavobacteriia,2PH89@252356|Maribacter	976|Bacteroidetes	E	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS2_k127_4845888_1	1237149.C900_01189	4.425e-114	375.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS2_k127_4845888_0	761193.Runsl_5127	2.217e-251	791.0	COG0365@1|root,COG0365@2|Bacteria,4NINZ@976|Bacteroidetes,47MVK@768503|Cytophagia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS2_k127_4845888_4	1048983.EL17_03370	2.96e-34	134.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,47RJW@768503|Cytophagia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS2_k127_4845888_3	1250005.PHEL85_1633	2.936e-42	162.0	COG2197@1|root,COG2197@2|Bacteria,4PIAP@976|Bacteroidetes,1ICD1@117743|Flavobacteriia,3VX57@52959|Polaribacter	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_4845888_2	509635.N824_26735	5.345e-49	185.0	COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS2_k127_4845888_5	1443665.JACA01000001_gene2900	6.086e-08	62.0	2ECA3@1|root,3368F@2|Bacteria,4NW35@976|Bacteroidetes,1IM9X@117743|Flavobacteriia,2YITU@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4878792_0	313603.FB2170_06085	2.006e-281	880.0	COG3525@1|root,COG3525@2|Bacteria,4NH2R@976|Bacteroidetes,1I12J@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
CMS2_k127_4878792_26	1121007.AUML01000006_gene3032	2.047e-23	103.0	COG0745@1|root,COG0745@2|Bacteria,4NV35@976|Bacteroidetes,1I3HP@117743|Flavobacteriia,2YJIM@290174|Aquimarina	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_4878792_5	1237149.C900_03859	2.182e-136	441.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,47KXF@768503|Cytophagia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS2_k127_4878792_16	880071.Fleli_1256	1.915e-105	349.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,47KXZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS2_k127_4878792_8	313603.FB2170_04860	5.939e-133	431.0	COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,1IIZQ@117743|Flavobacteriia	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
CMS2_k127_4878792_10	468059.AUHA01000002_gene577	9.297e-129	417.0	COG0573@1|root,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,1IPVZ@117747|Sphingobacteriia	976|Bacteroidetes	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS2_k127_4878792_17	1121288.AULL01000007_gene1423	1.45e-97	326.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1I16J@117743|Flavobacteriia	976|Bacteroidetes	P	permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS2_k127_4878792_12	1237149.C900_04449	2.521e-123	399.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,47NU6@768503|Cytophagia	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS2_k127_4878792_22	1341155.FSS13T_14320	1.536e-55	201.0	COG0704@1|root,COG0704@2|Bacteria,4NNT5@976|Bacteroidetes,1I1UU@117743|Flavobacteriia,2NTDB@237|Flavobacterium	976|Bacteroidetes	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS2_k127_4878792_9	1237149.C900_04445	6.922e-131	436.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47N3M@768503|Cytophagia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
CMS2_k127_4878792_11	1237149.C900_04453	2.524e-128	421.0	COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,47K0B@768503|Cytophagia	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CMS2_k127_4878792_29	1341181.FLJC2902T_05260	0.0009772	47.0	2CED8@1|root,32YZ6@2|Bacteria,4NVDS@976|Bacteroidetes,1I5AZ@117743|Flavobacteriia,2NWVN@237|Flavobacterium	976|Bacteroidetes	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
CMS2_k127_4878792_20	929703.KE386491_gene2765	1.399e-82	282.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
CMS2_k127_4878792_6	1237149.C900_04459	2.896e-135	436.0	COG2207@1|root,COG2207@2|Bacteria,4NFHF@976|Bacteroidetes,47MM1@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_4878792_1	1237149.C900_04460	8.135e-208	650.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47JZA@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_4878792_18	1123248.KB893381_gene975	7.424e-94	318.0	COG0673@1|root,COG0673@2|Bacteria,4NHFK@976|Bacteroidetes,1IUZY@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_4878792_13	1237149.C900_03938	5.02e-119	414.0	COG1729@1|root,COG1729@2|Bacteria,4PP99@976|Bacteroidetes,47VYS@768503|Cytophagia	976|Bacteroidetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
CMS2_k127_4878792_14	1237149.C900_01165	5.549e-114	372.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,47K6T@768503|Cytophagia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
CMS2_k127_4878792_19	1237149.C900_01166	1.143e-87	297.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS2_k127_4878792_24	1358423.N180_18730	3.436e-31	123.0	COG4892@1|root,COG4892@2|Bacteria,4NSAM@976|Bacteroidetes,1ITM0@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome b5-like Heme Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
CMS2_k127_4878792_23	1519464.HY22_14165	4.354e-52	192.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS2_k127_4878792_3	1237149.C900_01169	2.399e-168	538.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS2_k127_4878792_15	1124780.ANNU01000051_gene2079	7.26e-107	355.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,47MPK@768503|Cytophagia	976|Bacteroidetes	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CMS2_k127_4878792_28	485917.Phep_0234	3.774e-07	59.0	COG1377@1|root,COG1377@2|Bacteria,4NMN3@976|Bacteroidetes,1ISAJ@117747|Sphingobacteriia	976|Bacteroidetes	NU	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4878792_27	929556.Solca_4232	1.649e-18	93.0	COG1377@1|root,COG1377@2|Bacteria,4NMN3@976|Bacteroidetes,1ITYV@117747|Sphingobacteriia	976|Bacteroidetes	NU	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4878792_25	1408813.AYMG01000011_gene840	1.518e-25	115.0	29GF6@1|root,303CZ@2|Bacteria,4NR6I@976|Bacteroidetes,1IT48@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS2_k127_4878792_21	1121930.AQXG01000001_gene1053	3.239e-56	212.0	28IVH@1|root,2Z8TX@2|Bacteria,4NEEW@976|Bacteroidetes,1IQEF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
CMS2_k127_4878792_7	1178825.ALIH01000004_gene2848	9.142e-134	433.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS2_k127_4878792_4	313606.M23134_03031	4.436e-168	539.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,47JBI@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS2_k127_4878792_2	1237149.C900_05293	8.502e-207	665.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_4939676_1	1237149.C900_04204	2.086e-54	202.0	COG3291@1|root,COG4099@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG4932@2|Bacteria,4NP7H@976|Bacteroidetes,47XCB@768503|Cytophagia	976|Bacteroidetes	M	Immunoglobulin like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4939676_2	471854.Dfer_2914	1.084e-07	64.0	COG0226@1|root,COG0226@2|Bacteria,4NKND@976|Bacteroidetes,47PVA@768503|Cytophagia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_4939676_0	1237149.C900_04202	3.934e-94	332.0	COG2353@1|root,COG4099@1|root,COG4733@1|root,COG5498@1|root,COG2353@2|Bacteria,COG4099@2|Bacteria,COG4733@2|Bacteria,COG5498@2|Bacteria	2|Bacteria	M	chitin catabolic process	-	-	3.2.1.136	ko:K02358,ko:K15924	-	-	-	-	ko00000,ko01000,ko03012,ko03029,ko04147	-	GH5	-	Abhydrolase_8,CBM_6,PA14,RicinB_lectin_2,fn3
CMS2_k127_5080683_0	218284.CCDN010000001_gene893	1.132e-12	72.0	28VWJ@1|root,2ZHXX@2|Bacteria,1W3TF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5092650_0	1499967.BAYZ01000080_gene893	7.289e-39	147.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K18830	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,TIR_2
CMS2_k127_5092650_2	1121456.ATVA01000015_gene2425	7.035e-05	49.0	COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,42WHD@68525|delta/epsilon subdivisions,2WSDG@28221|Deltaproteobacteria,2MDDQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS2_k127_5092650_1	706587.Desti_4932	7.672e-19	87.0	COG0662@1|root,COG0662@2|Bacteria,1N74G@1224|Proteobacteria	1224|Proteobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
CMS2_k127_5104078_1	421072.IO89_17465	3.124e-67	232.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,4NI8N@976|Bacteroidetes,1HZ7Z@117743|Flavobacteriia	976|Bacteroidetes	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
CMS2_k127_5104078_3	869213.JCM21142_3921	1.846e-19	91.0	COG3093@1|root,COG3093@2|Bacteria,4NMVH@976|Bacteroidetes,47WP5@768503|Cytophagia	976|Bacteroidetes	K	plasmid maintenance system antidote protein	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CMS2_k127_5104078_0	616991.JPOO01000003_gene41	1.049e-109	366.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,Polysacc_deac_1
CMS2_k127_5104078_2	1122176.KB903571_gene4790	2.068e-40	152.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IQ00@117747|Sphingobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_5105372_7	1237149.C900_04309	1.394e-65	226.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_5105372_5	1237149.C900_04310	5.203e-85	285.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_5105372_0	643867.Ftrac_3106	1.743e-249	775.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS2_k127_5105372_11	1216967.L100_08664	3.688e-14	81.0	COG3637@1|root,COG3637@2|Bacteria,4NVT2@976|Bacteroidetes,1I8VN@117743|Flavobacteriia,34RGW@308865|Elizabethkingia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_5105372_12	225400.XP_006779277.1	0.000611	46.0	KOG4295@1|root,KOG4295@2759|Eukaryota,39W2M@33154|Opisthokonta,3BFPP@33208|Metazoa,3D4UK@33213|Bilateria,48BPC@7711|Chordata,4972A@7742|Vertebrata,3J494@40674|Mammalia,4KPG4@9397|Chiroptera	33208|Metazoa	O	Tissue factor pathway inhibitor	TFPI2	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Kunitz_BPTI
CMS2_k127_5105372_8	1121904.ARBP01000010_gene2414	4.86e-61	217.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47PZB@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CMS2_k127_5105372_6	868131.MSWAN_1997	7.62e-69	240.0	COG4912@1|root,arCOG05122@2157|Archaea,2Y8HF@28890|Euryarchaeota,23PXI@183925|Methanobacteria	183925|Methanobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS2_k127_5105372_9	1235799.C818_02739	2.294e-39	147.0	COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,24MYT@186801|Clostridia,27PGR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
CMS2_k127_5105372_10	1048983.EL17_13010	1.011e-15	79.0	COG2161@1|root,COG2161@2|Bacteria,4NT64@976|Bacteroidetes,47SVX@768503|Cytophagia	976|Bacteroidetes	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
CMS2_k127_5105372_3	1123057.P872_24355	1.946e-163	524.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,47JDY@768503|Cytophagia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_5105372_1	926549.KI421517_gene39	7.698e-191	601.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CMS2_k127_5105372_4	655815.ZPR_2877	9.039e-116	385.0	COG0420@1|root,COG0420@2|Bacteria,4NEET@976|Bacteroidetes,1HYF2@117743|Flavobacteriia	976|Bacteroidetes	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
CMS2_k127_5105372_2	1392489.JPOL01000002_gene3129	1.304e-165	557.0	COG0419@1|root,COG0419@2|Bacteria,4NH9H@976|Bacteroidetes,1HYCM@117743|Flavobacteriia,2XHVX@283735|Leeuwenhoekiella	976|Bacteroidetes	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
CMS2_k127_5107525_0	1121897.AUGO01000002_gene2114	2.105e-103	348.0	COG3903@1|root,COG3903@2|Bacteria,4PA12@976|Bacteroidetes,1INJA@117743|Flavobacteriia,2NZTQ@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5112642_0	1123248.KB893317_gene4298	1.969e-294	910.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IWH6@117747|Sphingobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS2_k127_5112642_6	1123248.KB893317_gene4299	1.502e-25	114.0	2CDAN@1|root,309X8@2|Bacteria,4NP84@976|Bacteroidetes,1IUB9@117747|Sphingobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_5112642_3	1250278.JQNQ01000001_gene1163	1.922e-84	286.0	COG1346@1|root,COG1346@2|Bacteria,4NM6T@976|Bacteroidetes,1I1G7@117743|Flavobacteriia	976|Bacteroidetes	M	of murein	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
CMS2_k127_5112642_5	1250278.JQNQ01000001_gene1164	9.999e-39	147.0	COG1380@1|root,COG1380@2|Bacteria,4NT9H@976|Bacteroidetes,1I4M6@117743|Flavobacteriia	976|Bacteroidetes	S	LrgA family	-	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
CMS2_k127_5112642_1	1123248.KB893381_gene1115	1.63e-180	585.0	COG3589@1|root,COG3589@2|Bacteria,4NE7B@976|Bacteroidetes	976|Bacteroidetes	G	Pfam Glycoside hydrolase 97	-	-	-	-	-	-	-	-	-	-	-	-	GH97_C,GH97_N,Glyco_hydro_97
CMS2_k127_5112642_4	906888.JCM19314_1965	4.604e-80	270.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia,3HJJI@363408|Nonlabens	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS2_k127_5112642_2	1239962.C943_03674	8.577e-163	539.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47KSH@768503|Cytophagia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,CarbopepD_reg_2,Plug
CMS2_k127_5148951_0	927658.AJUM01000033_gene1418	3.295e-127	415.0	COG3177@1|root,COG3177@2|Bacteria,4NF0H@976|Bacteroidetes,2FPDB@200643|Bacteroidia,3XKFM@558415|Marinilabiliaceae	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
CMS2_k127_5148951_1	1237149.C900_02843	1.241e-13	75.0	COG3209@1|root,COG3209@2|Bacteria,4NQH6@976|Bacteroidetes	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_22	1237149.C900_04532	1.236e-78	267.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,47PUM@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_9	1237149.C900_04531	4.519e-175	559.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,47JUX@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldE	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS2_k127_5163986_23	643867.Ftrac_2590	2.602e-56	200.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS2_k127_5163986_16	313603.FB2170_07469	2.621e-99	335.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia,2PGRP@252356|Maribacter	976|Bacteroidetes	L	FES	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS2_k127_5163986_28	761193.Runsl_4607	3.833e-08	54.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes,47T08@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_5	1237149.C900_04526	1.295e-244	765.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,47KC6@768503|Cytophagia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS2_k127_5163986_19	1237149.C900_03193	5.33e-89	302.0	COG2017@1|root,COG2017@2|Bacteria,4NE32@976|Bacteroidetes,47KZH@768503|Cytophagia	976|Bacteroidetes	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_15	1237149.C900_03194	1.788e-138	450.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_5163986_6	1237149.C900_00885	2.173e-223	709.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
CMS2_k127_5163986_1	929562.Emtol_2257	0.0	1037.0	COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47M4N@768503|Cytophagia	976|Bacteroidetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS2_k127_5163986_3	616991.JPOO01000003_gene1732	9.493e-262	811.0	COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,1I00J@117743|Flavobacteriia,23HRP@178469|Arenibacter	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS2_k127_5163986_10	1089547.KB913013_gene4649	2.218e-169	556.0	COG4886@1|root,COG4886@2|Bacteria,4NG07@976|Bacteroidetes,47P4Q@768503|Cytophagia	976|Bacteroidetes	S	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
CMS2_k127_5163986_25	688270.Celal_4238	5.559e-35	149.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia,1F8YY@104264|Cellulophaga	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_7,TPR_8
CMS2_k127_5163986_27	1121012.AUKX01000047_gene2041	4.866e-28	128.0	COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia,23G06@178469|Arenibacter	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_10,TPR_12,TPR_7,TPR_8
CMS2_k127_5163986_14	1237149.C900_04082	9.051e-142	454.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,47J9D@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_5163986_17	1288963.ADIS_4135	4.063e-99	331.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,47JAY@768503|Cytophagia	976|Bacteroidetes	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS2_k127_5163986_30	1121904.ARBP01000034_gene1830	1.726e-05	57.0	2BUNJ@1|root,32PZE@2|Bacteria,4NQFC@976|Bacteroidetes,47VU5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_2	1305737.JAFX01000001_gene2847	5.57e-291	908.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,47JUE@768503|Cytophagia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS2_k127_5163986_20	1237149.C900_01523	4.376e-87	295.0	28IIU@1|root,2Z8JV@2|Bacteria,4NEFH@976|Bacteroidetes,47JU3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_11	1237149.C900_04925	1.327e-157	510.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,47PIJ@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM exonuclease, DNA polymerase III, epsilon subunit family	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
CMS2_k127_5163986_26	1237149.C900_02061	8.412e-34	139.0	2DGJ8@1|root,2ZW7H@2|Bacteria,4P7SP@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_21	1185876.BN8_05457	1.323e-79	271.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,47KW3@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS2_k127_5163986_0	1237149.C900_01516	0.0	1341.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,47JVJ@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
CMS2_k127_5163986_7	1317122.ATO12_21630	2.611e-181	574.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia,2YI8I@290174|Aquimarina	976|Bacteroidetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS2_k127_5163986_4	1237149.C900_00894	1.377e-253	799.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
CMS2_k127_5163986_24	1008457.BAEX01000095_gene2545	6.938e-36	142.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia,47HND@76831|Myroides	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_13	1048983.EL17_13750	1.63e-142	456.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,47KRT@768503|Cytophagia	976|Bacteroidetes	C	PFAM Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS2_k127_5163986_8	1237149.C900_00901	6.938e-179	569.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,47JED@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
CMS2_k127_5163986_18	1123248.KB893324_gene1673	1.554e-92	318.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1IVD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5163986_12	945713.IALB_1952	3.191e-154	490.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11
CMS2_k127_5164760_2	1237149.C900_01754	5.021e-63	219.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,47JVI@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS2_k127_5164760_4	1237149.C900_01753	1.836e-16	79.0	2E359@1|root,32P2Z@2|Bacteria,4NWAD@976|Bacteroidetes,47SNB@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
CMS2_k127_5164760_3	643867.Ftrac_2017	3.005e-28	114.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,47S6V@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS2_k127_5164760_0	387092.NIS_1187	1.32e-276	884.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS2_k127_5164760_1	1168289.AJKI01000014_gene2057	7.886e-73	248.0	COG2273@1|root,COG2273@2|Bacteria,4NGMJ@976|Bacteroidetes,2FQ32@200643|Bacteroidia,3XM1D@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 16	bglA_1	-	-	-	-	-	-	-	-	-	-	-	DUF4971,Glyco_hydro_16
CMS2_k127_5199060_13	1237149.C900_02878	2.698e-113	393.0	COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes,47S64@768503|Cytophagia	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS2_k127_5199060_30	1237149.C900_03083	4.125e-35	138.0	COG1017@1|root,COG1017@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Globin
CMS2_k127_5199060_28	1189612.A33Q_4424	2.947e-46	171.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,47QMM@768503|Cytophagia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS2_k127_5199060_10	1237149.C900_02882	4.674e-145	463.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,47K8P@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS2_k127_5199060_23	1237149.C900_02945	2.259e-59	211.0	COG2340@1|root,COG2340@2|Bacteria,4NRNN@976|Bacteroidetes,47RRN@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS2_k127_5199060_22	866536.Belba_1152	2.345e-64	223.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,47PCJ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS2_k127_5199060_21	1237149.C900_04663	1.067e-68	240.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,47PPQ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
CMS2_k127_5199060_9	1237149.C900_04665	1.976e-165	527.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,47M0Z@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS2_k127_5199060_16	1185876.BN8_05994	2.256e-91	314.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,47JMB@768503|Cytophagia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
CMS2_k127_5199060_34	1237149.C900_04667	4.049e-15	78.0	COG5512@1|root,COG5512@2|Bacteria,4NXIK@976|Bacteroidetes,47S8C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS2_k127_5199060_6	1121859.KB890757_gene1661	1.75e-234	728.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS2_k127_5199060_33	1124780.ANNU01000035_gene255	1.808e-22	98.0	COG0690@1|root,COG0690@2|Bacteria,4NX53@976|Bacteroidetes,47RVC@768503|Cytophagia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS2_k127_5199060_14	1237149.C900_04670	1.882e-100	329.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,47KBF@768503|Cytophagia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS2_k127_5199060_18	1237149.C900_04671	2.658e-80	269.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,47PEZ@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS2_k127_5199060_12	1237149.C900_04672	1.998e-116	380.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,47JJZ@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS2_k127_5199060_24	1123057.P872_23055	6.005e-58	207.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,47JGP@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS2_k127_5199060_26	866536.Belba_1701	1.063e-52	188.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,47PSQ@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS2_k127_5199060_1	1237149.C900_04675	0.0	2246.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,47JXH@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS2_k127_5199060_0	1237149.C900_04676	0.0	2492.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,47JP0@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS2_k127_5199060_27	1237149.C900_04677	2.622e-51	183.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,47R37@768503|Cytophagia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
CMS2_k127_5199060_20	926549.KI421517_gene267	6.93e-72	243.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,47PCE@768503|Cytophagia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS2_k127_5199060_19	1124780.ANNU01000035_gene245	3.97e-76	257.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,47P7P@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS2_k127_5199060_2	880070.Cycma_2587	0.0	1188.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_5199060_25	1237149.C900_04681	7.851e-57	199.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,47Q8W@768503|Cytophagia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS2_k127_5199060_31	755732.Fluta_0803	6.92e-30	122.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2PB27@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM single stranded DNA-binding protein (ssb)	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS2_k127_5199060_32	1305737.JAFX01000001_gene1341	9.869e-27	113.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,47QXI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
CMS2_k127_5199060_11	1121129.KB903367_gene2699	1.518e-138	455.0	COG1502@1|root,COG1502@2|Bacteria,4NE2W@976|Bacteroidetes,2FMEA@200643|Bacteroidia,22W66@171551|Porphyromonadaceae	976|Bacteroidetes	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS2_k127_5199060_5	1237149.C900_01880	2.431e-235	751.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,47KYC@768503|Cytophagia	976|Bacteroidetes	M	penicillin-binding protein 1C	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CMS2_k127_5199060_15	1237149.C900_01882	8.146e-97	332.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS2_k127_5199060_4	643867.Ftrac_2237	6.915e-280	866.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_5199060_29	1237149.C900_02070	7.763e-45	169.0	COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
CMS2_k127_5199060_8	313606.M23134_05244	4.416e-183	581.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_5199060_7	1121904.ARBP01000008_gene3427	1.06e-213	690.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_5199060_3	1121104.AQXH01000002_gene717	0.0	1174.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IW7V@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_5199060_17	1121904.ARBP01000006_gene3917	1.82e-90	299.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,47NC5@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS2_k127_5214424_4	643867.Ftrac_2218	3.723e-20	91.0	COG1215@1|root,COG1215@2|Bacteria,4PKM6@976|Bacteroidetes,47XW9@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_5214424_1	761193.Runsl_4693	3.189e-50	190.0	COG1216@1|root,COG1216@2|Bacteria,4PMS2@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_5214424_3	1042209.HK44_026175	4.801e-24	110.0	COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria,1YNS4@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS2_k127_5214424_2	913865.DOT_4238	7.143e-37	146.0	COG0110@1|root,COG0110@2|Bacteria,1VFFY@1239|Firmicutes	1239|Firmicutes	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS2_k127_5214424_0	525904.Tter_2802	4.282e-65	231.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS2_k127_5245403_4	762903.Pedsa_0637	1.234e-82	282.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1IQPQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS2_k127_5245403_5	4950.XP_003680372.1	1.244e-05	57.0	COG0457@1|root,KOG1126@2759|Eukaryota,38DG8@33154|Opisthokonta,3NW4C@4751|Fungi,3QK37@4890|Ascomycota,3RT06@4891|Saccharomycetes,3RZHQ@4893|Saccharomycetaceae	4751|Fungi	D	to Saccharomyces cerevisiae CDC27 (YBL084C)	CDC27	GO:0000070,GO:0000151,GO:0000152,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0022402,GO:0030071,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051276,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0090068,GO:0097159,GO:0098813,GO:0140014,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252	-	ko:K03350	ko04110,ko04111,ko04113,ko04114,ko04120,ko04914,ko05166,map04110,map04111,map04113,map04114,map04120,map04914,map05166	M00389	-	-	ko00000,ko00001,ko00002,ko01009,ko03036,ko04121	-	-	-	ANAPC3,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
CMS2_k127_5245403_2	1123248.KB893326_gene1452	6.73e-108	356.0	COG1082@1|root,COG1082@2|Bacteria,4NFMD@976|Bacteroidetes,1IVV3@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_5245403_0	1124780.ANNU01000025_gene3340	0.0	1107.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,47JGX@768503|Cytophagia	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,PD40
CMS2_k127_5245403_1	1406840.Q763_07515	1.432e-171	546.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,1HXI9@117743|Flavobacteriia,2NTWF@237|Flavobacterium	976|Bacteroidetes	S	Dehydrogenase	-	-	1.1.1.1	ko:K13953,ko:K13979	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS2_k127_5245403_3	926562.Oweho_1240	2.322e-85	295.0	COG5279@1|root,COG5279@2|Bacteria,4NKJ4@976|Bacteroidetes,1HZ5K@117743|Flavobacteriia,2PB8F@246874|Cryomorphaceae	976|Bacteroidetes	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS2_k127_5272823_3	643867.Ftrac_0352	5.347e-32	129.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes	976|Bacteroidetes	J	chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS2_k127_5272823_0	1237149.C900_05170	3.505e-262	819.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47MDS@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CMS2_k127_5272823_1	1408473.JHXO01000008_gene2856	5.55e-142	462.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase	-	-	2.6.1.1,2.6.1.88	ko:K00812,ko:K10907,ko:K14287	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08618	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_5272823_2	1280949.HAD_05125	5.82e-131	436.0	COG0405@1|root,COG0405@2|Bacteria,1Q089@1224|Proteobacteria,2U8PM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS2_k127_5291127_0	929703.KE386491_gene883	3.865e-164	529.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,47JRR@768503|Cytophagia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS2_k127_5311014_16	1305737.JAFX01000001_gene2831	2.805e-87	302.0	COG0438@1|root,COG0438@2|Bacteria,4NI16@976|Bacteroidetes,47KFJ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS2_k127_5311014_8	1121904.ARBP01000012_gene1293	5.1e-186	601.0	COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria	2|Bacteria	P	domain protein	yjbQ	-	-	ko:K03455,ko:K03499	-	-	-	-	ko00000,ko02000	2.A.37,2.A.38.1,2.A.38.4	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS2_k127_5311014_21	1124780.ANNU01000006_gene2903	7.516e-72	250.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,47KFE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
CMS2_k127_5311014_28	313603.FB2170_15583	1.205e-51	191.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	yxbB	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS2_k127_5311014_31	880071.Fleli_2856	8.413e-47	175.0	2BVCI@1|root,32QSK@2|Bacteria,4NS0Z@976|Bacteroidetes,47W1V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5311014_35	1380384.JADN01000003_gene948	7.165e-10	60.0	2BVCI@1|root,32QSK@2|Bacteria,4NS0Z@976|Bacteroidetes,1I3PQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5311014_4	1237149.C900_01463	7.038e-255	794.0	COG2303@1|root,COG2303@2|Bacteria,4NIU5@976|Bacteroidetes,47RDM@768503|Cytophagia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CMS2_k127_5311014_3	1121875.KB907549_gene1920	1.582e-267	831.0	COG5476@1|root,COG5476@2|Bacteria,4NG23@976|Bacteroidetes,1I0K5@117743|Flavobacteriia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS2_k127_5311014_12	1237149.C900_01735	9.59e-132	446.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,47MFU@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS2_k127_5311014_26	1237149.C900_01549	3.3e-54	196.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS2_k127_5311014_9	1237149.C900_01547	7.714e-183	585.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia	976|Bacteroidetes	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
CMS2_k127_5311014_22	1124780.ANNU01000006_gene2845	3.8e-64	225.0	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,47PFV@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_5311014_6	1237149.C900_00754	4.41e-228	716.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_5311014_13	1121904.ARBP01000010_gene2342	8.209e-122	403.0	COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_5311014_25	313606.M23134_01760	1.656e-55	211.0	COG5002@1|root,COG5002@2|Bacteria,4PKXY@976|Bacteroidetes	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
CMS2_k127_5311014_0	1237149.C900_04538	0.0	1482.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5311014_19	1237149.C900_04537	3.39e-78	270.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,47JQR@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS2_k127_5311014_15	153721.MYP_4450	8.588e-106	348.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS2_k127_5311014_23	1237149.C900_04549	4.547e-64	232.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,47XED@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
CMS2_k127_5311014_27	1237149.C900_04548	2.3e-53	196.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,47R3Y@768503|Cytophagia	976|Bacteroidetes	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
CMS2_k127_5311014_37	1121373.KB903622_gene2779	1.012e-06	55.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,47R3Y@768503|Cytophagia	976|Bacteroidetes	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
CMS2_k127_5311014_24	1443665.JACA01000007_gene184	1.864e-58	205.0	2C1EG@1|root,2Z7MZ@2|Bacteria,4NYQE@976|Bacteroidetes,1IBSY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5311014_2	1237149.C900_04649	5.467e-302	934.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,47KH2@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_5311014_7	1237149.C900_04650	2.017e-192	606.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JQD@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS2_k127_5311014_1	1237149.C900_04651	0.0	1311.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,47ME4@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS2_k127_5311014_30	866536.Belba_1012	5.672e-47	173.0	COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,47QHS@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS2_k127_5311014_29	1341181.FLJC2902T_25780	3.044e-48	195.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,1IKW5@117743|Flavobacteriia,2P01K@237|Flavobacterium	976|Bacteroidetes	T	Four helix bundle sensory module for signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_9
CMS2_k127_5311014_32	748727.CLJU_c38830	3.011e-32	145.0	COG2199@1|root,COG3706@2|Bacteria,1VJNQ@1239|Firmicutes,25FV2@186801|Clostridia,36UZC@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Peripla_BP_3
CMS2_k127_5311014_17	143224.JQMD01000002_gene3708	3.131e-87	296.0	COG1082@1|root,COG1082@2|Bacteria,4NIWS@976|Bacteroidetes,1I5YW@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS2_k127_5311014_11	886377.Murru_0617	2.443e-155	501.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,1HZ8W@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_5311014_33	1107311.Q767_07710	2.176e-23	113.0	COG3209@1|root,COG3209@2|Bacteria,4NRDA@976|Bacteroidetes,1I3N8@117743|Flavobacteriia,2NZ0Z@237|Flavobacterium	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5311014_18	153721.MYP_4547	1.52e-78	268.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,47MWN@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS2_k127_5311014_5	1237149.C900_02782	3.248e-246	763.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47K4Z@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_5311014_14	866536.Belba_1247	2.994e-106	351.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,47KPM@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS2_k127_5311014_20	1237149.C900_02779	6.859e-78	271.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,47JZ8@768503|Cytophagia	976|Bacteroidetes	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS2_k127_5311014_10	1237149.C900_02778	2.955e-170	538.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
CMS2_k127_5335223_15	1237149.C900_04304	7.599e-13	68.0	COG1396@1|root,COG1396@2|Bacteria,4NR5F@976|Bacteroidetes,47VXZ@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_5335223_2	1237149.C900_05294	4.045e-258	820.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_5335223_6	1122137.AQXF01000004_gene1524	2.294e-150	486.0	COG0477@1|root,COG2814@2|Bacteria,1QWEI@1224|Proteobacteria,2U6BP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
CMS2_k127_5335223_12	1124780.ANNU01000020_gene3260	1.898e-44	167.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,47QG8@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
CMS2_k127_5335223_5	1237149.C900_00949	1.517e-154	508.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,47KQH@768503|Cytophagia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS2_k127_5335223_4	643867.Ftrac_1088	1.992e-160	510.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,47K22@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
CMS2_k127_5335223_0	1124780.ANNU01000045_gene2285	6.395e-300	933.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,47JB3@768503|Cytophagia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS2_k127_5335223_14	385682.AFSL01000074_gene1233	3.247e-16	80.0	COG3630@1|root,COG3630@2|Bacteria,4NXVZ@976|Bacteroidetes,2G1YC@200643|Bacteroidia,3XKDF@558415|Marinilabiliaceae	976|Bacteroidetes	C	Sodium pump decarboxylase gamma subunit	-	-	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
CMS2_k127_5335223_1	1121904.ARBP01000007_gene2990	5.606e-286	889.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4NEQV@976|Bacteroidetes	976|Bacteroidetes	C	COG5016 Pyruvate oxaloacetate carboxyltransferase	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Biotin_lipoyl_2,HMGL-like,PYC_OADA
CMS2_k127_5335223_3	1121904.ARBP01000007_gene2989	2.895e-174	554.0	COG1883@1|root,COG1883@2|Bacteria,4NGCN@976|Bacteroidetes	976|Bacteroidetes	C	sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
CMS2_k127_5335223_8	1237149.C900_00381	4.048e-73	250.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47PTY@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_5335223_9	1237149.C900_00383	8.457e-73	254.0	COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,47Y4X@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_5335223_10	1237149.C900_00383	5.119e-59	213.0	COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,47Y4X@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_5335223_13	1121373.KB903643_gene3467	7.247e-33	133.0	2E2N8@1|root,32XRD@2|Bacteria,4NSR6@976|Bacteroidetes,47VN4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5335223_7	1237149.C900_04758	2.212e-92	338.0	COG4251@1|root,COG4251@2|Bacteria,4NIJY@976|Bacteroidetes,47U6D@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS
CMS2_k127_5335223_11	926559.JoomaDRAFT_2197	1.188e-54	194.0	COG2346@1|root,COG2346@2|Bacteria,4NQCV@976|Bacteroidetes,1I35V@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS2_k127_5348955_2	153721.MYP_4888	3.947e-138	452.0	COG0643@1|root,COG0643@2|Bacteria,4NG31@976|Bacteroidetes,47MM7@768503|Cytophagia	976|Bacteroidetes	NT	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS2_k127_5348955_5	153721.MYP_4869	2.049e-54	195.0	COG0835@1|root,COG0835@2|Bacteria,4NTK7@976|Bacteroidetes,47X59@768503|Cytophagia	976|Bacteroidetes	NT	Two component signalling adaptor domain	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS2_k127_5348955_3	153721.MYP_4871	1.468e-95	320.0	COG1352@1|root,COG1352@2|Bacteria,4NJ75@976|Bacteroidetes,47RGQ@768503|Cytophagia	976|Bacteroidetes	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS2_k127_5348955_4	869213.JCM21142_451	3.424e-57	210.0	COG0642@1|root,COG2205@2|Bacteria,4NNN3@976|Bacteroidetes,47USF@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS2_k127_5348955_6	385682.AFSL01000008_gene2579	1.918e-48	177.0	COG1871@1|root,COG1871@2|Bacteria,4NQUM@976|Bacteroidetes,2G1N1@200643|Bacteroidia,3XJZE@558415|Marinilabiliaceae	976|Bacteroidetes	NT	CheD chemotactic sensory transduction	cheD	-	-	-	-	-	-	-	-	-	-	-	CheD
CMS2_k127_5348955_1	573370.DMR_23750	1.04e-147	476.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,2M8VE@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB34H	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS2_k127_5348955_7	1237149.C900_03994	9.824e-41	160.0	2A7CX@1|root,334RT@2|Bacteria,4NVQR@976|Bacteroidetes,47RXJ@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_5348955_9	1313421.JHBV01000005_gene4531	5.641e-13	76.0	28V38@1|root,2ZH6M@2|Bacteria,4PPW0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5348955_8	1313301.AUGC01000003_gene2113	2.694e-33	132.0	COG2197@1|root,COG2197@2|Bacteria,4PPMZ@976|Bacteroidetes	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_5348955_11	1121011.AUCB01000021_gene3788	1.491e-06	59.0	28NAV@1|root,2ZBEH@2|Bacteria,4NJGP@976|Bacteroidetes,1I0G3@117743|Flavobacteriia,23HTB@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5348955_10	926549.KI421517_gene1436	8.125e-11	71.0	2E4RS@1|root,32ZKA@2|Bacteria,4NVN5@976|Bacteroidetes,47RDU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5348955_0	1123277.KB893195_gene5709	1.481e-235	756.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47K68@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5365584_0	1120965.AUBV01000004_gene1037	1.225e-175	571.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
CMS2_k127_5365584_4	886379.AEWI01000040_gene2784	3.924e-40	172.0	COG1418@1|root,COG2114@1|root,COG1418@2|Bacteria,COG2114@2|Bacteria,4NFAG@976|Bacteroidetes,2G21A@200643|Bacteroidia,3XIWF@558415|Marinilabiliaceae	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
CMS2_k127_5365584_3	1379698.RBG1_1C00001G0607	1.47e-49	202.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
CMS2_k127_5365584_2	1237149.C900_00650	1.215e-54	200.0	COG1943@1|root,COG1943@2|Bacteria,4NPWC@976|Bacteroidetes,47RHZ@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS2_k127_5365584_1	1408473.JHXO01000009_gene3392	3.991e-78	267.0	COG4030@1|root,COG4030@2|Bacteria,4NHV9@976|Bacteroidetes,2FNZY@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS2_k127_5432521_2	1237149.C900_03446	8.194e-142	471.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,47KGC@768503|Cytophagia	976|Bacteroidetes	L	PFAM DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
CMS2_k127_5432521_1	1237149.C900_04617	1.152e-155	513.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
CMS2_k127_5432521_0	1123057.P872_08200	8.869e-161	515.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CMS2_k127_5432521_3	1237149.C900_04619	1.9e-78	264.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,47PQS@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS2_k127_5464327_7	1434325.AZQN01000003_gene2786	9.449e-22	98.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47JJJ@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5464327_2	1296415.JACC01000011_gene570	3.019e-152	493.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1HY94@117743|Flavobacteriia,2YM0B@290174|Aquimarina	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS2_k127_5464327_0	143224.JQMD01000002_gene2503	0.0	1178.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_5464327_1	761193.Runsl_0234	2.393e-158	511.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_5464327_4	1237149.C900_01193	2.379e-86	294.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,47KM1@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CMS2_k127_5464327_8	1279009.ADICEAN_02323	1.099e-20	92.0	2DQ4W@1|root,334SC@2|Bacteria,4NUQX@976|Bacteroidetes,47RZV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3098
CMS2_k127_5464327_3	926556.Echvi_3275	7.476e-91	305.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS2_k127_5464327_5	866536.Belba_3569	7.811e-74	255.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,47P98@768503|Cytophagia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
CMS2_k127_5464327_9	1048983.EL17_08665	1.648e-11	64.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS2_k127_5500371_5	1237149.C900_04091	1.782e-136	436.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_5500371_3	1237149.C900_04092	6.201e-188	594.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,47N10@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_5500371_1	1237149.C900_04093	2.282e-235	735.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_5500371_8	485918.Cpin_0952	2.915e-116	390.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1IX7U@117747|Sphingobacteriia	976|Bacteroidetes	T	PAS PAC sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
CMS2_k127_5500371_10	643867.Ftrac_0060	1.318e-65	228.0	COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia	976|Bacteroidetes	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS2_k127_5500371_4	1122176.KB903537_gene1649	6.624e-166	529.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,1IW76@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_5500371_13	232346.JHQL01000007_gene1960	6.175e-30	123.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XKEP@135619|Oceanospirillales	135619|Oceanospirillales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS2_k127_5500371_0	313603.FB2170_04380	0.0	1242.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PGXR@252356|Maribacter	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_5500371_6	1124780.ANNU01000049_gene2169	7.66e-133	434.0	COG1404@1|root,COG1404@2|Bacteria,4NI53@976|Bacteroidetes,47MBD@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
CMS2_k127_5500371_11	1288963.ADIS_3236	1.436e-54	194.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,47QN1@768503|Cytophagia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
CMS2_k127_5500371_7	1121012.AUKX01000070_gene1860	1.428e-119	396.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,1HYYV@117743|Flavobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CMS2_k127_5500371_12	313606.M23134_07087	2.163e-33	138.0	28P2C@1|root,2ZBYG@2|Bacteria,4NMEQ@976|Bacteroidetes,47PKX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5500371_15	471874.PROSTU_04501	3.634e-05	54.0	COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1S0JJ@1236|Gammaproteobacteria,3Z7EQ@586|Providencia	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS2_k127_5500371_2	1121904.ARBP01000002_gene7252	2.216e-190	622.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_5500371_9	1121904.ARBP01000006_gene3917	2.239e-83	279.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,47NC5@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS2_k127_55171_1	471854.Dfer_4999	1.181e-99	329.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS2_k127_55171_2	643867.Ftrac_2001	1.234e-91	308.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS2_k127_55171_5	1408433.JHXV01000027_gene3708	6.195e-46	169.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,Cytochrome_P460,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M
CMS2_k127_55171_3	1120966.AUBU01000027_gene529	2.121e-90	299.0	COG2128@1|root,COG2128@2|Bacteria,4NH2M@976|Bacteroidetes,47PX1@768503|Cytophagia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS2_k127_55171_0	1041826.FCOL_05735	2.647e-123	400.0	COG2207@1|root,COG2207@2|Bacteria,4NIW3@976|Bacteroidetes,1I0M9@117743|Flavobacteriia,2P0EF@237|Flavobacterium	976|Bacteroidetes	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_55171_6	504472.Slin_2273	3.144e-10	63.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS2_k127_55171_4	746697.Aeqsu_3156	1.527e-58	206.0	COG0454@1|root,COG0454@2|Bacteria,4NPMJ@976|Bacteroidetes,1I2CX@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_55171_7	862965.PARA_13210	2.484e-09	59.0	2ATIV@1|root,31J2V@2|Bacteria,1QI4I@1224|Proteobacteria,1TFY1@1236|Gammaproteobacteria,1YAFM@135625|Pasteurellales	135625|Pasteurellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5523266_1	1121007.AUML01000066_gene591	3.691e-22	108.0	COG3209@1|root,COG3209@2|Bacteria,4NWZN@976|Bacteroidetes,1I52Z@117743|Flavobacteriia,2YM4H@290174|Aquimarina	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5523266_0	984262.SGRA_3924	1.327e-22	109.0	COG3209@1|root,COG3209@2|Bacteria,4NURR@976|Bacteroidetes,1IYN7@117747|Sphingobacteriia	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5532257_1	1237149.C900_01101	2.952e-210	680.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CMS2_k127_5532257_3	1122176.KB903548_gene1207	5.112e-160	510.0	COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,1IP1W@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS2_k127_5532257_2	1123248.KB893326_gene1256	1.201e-181	569.0	COG0451@1|root,COG0451@2|Bacteria,4NHPA@976|Bacteroidetes,1IVQF@117747|Sphingobacteriia	976|Bacteroidetes	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS2_k127_5532257_0	616991.JPOO01000001_gene4502	1.597e-235	734.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,1HYAT@117743|Flavobacteriia,23G1H@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
CMS2_k127_5532257_4	1089547.KB913013_gene4338	7.105e-123	398.0	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,47NTC@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS2_k127_5532257_5	1317122.ATO12_10165	1.152e-104	342.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia,2YIIY@290174|Aquimarina	976|Bacteroidetes	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS2_k127_5532257_6	926562.Oweho_1894	6.74e-101	339.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,1HXW5@117743|Flavobacteriia,2PAFU@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
CMS2_k127_5552949_0	153721.MYP_3046	0.0	1022.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
CMS2_k127_5552949_2	388413.ALPR1_16264	4.51e-151	486.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,47JI6@768503|Cytophagia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS2_k127_5552949_4	313606.M23134_04128	6.596e-124	437.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47Y2E@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS2_k127_5552949_6	313606.M23134_06660	1.982e-72	257.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,4NGZ0@976|Bacteroidetes,47PW9@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,Response_reg
CMS2_k127_5552949_1	1305737.JAFX01000001_gene170	1.33e-286	900.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47N4P@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS2_k127_5552949_10	643867.Ftrac_2337	5.932e-16	79.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS2_k127_5552949_8	313606.M23134_07610	1.292e-31	128.0	COG2153@1|root,COG2153@2|Bacteria,4NT5M@976|Bacteroidetes,47Q2T@768503|Cytophagia	976|Bacteroidetes	S	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS2_k127_5552949_3	1124780.ANNU01000021_gene2975	4.986e-146	468.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,47JUG@768503|Cytophagia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS2_k127_5552949_5	1237149.C900_02698	1.186e-74	258.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,47PDG@768503|Cytophagia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
CMS2_k127_5552949_9	1120966.AUBU01000002_gene2011	6.088e-28	115.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,47R4E@768503|Cytophagia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS2_k127_5552949_11	1211814.CAPG01000082_gene3799	1.464e-06	51.0	2BF4Y@1|root,328X8@2|Bacteria,1UB8H@1239|Firmicutes,4IMM8@91061|Bacilli,1ZKEI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5552949_7	929556.Solca_1658	8.755e-56	199.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_5604948_2	760192.Halhy_3044	4.15e-24	111.0	COG1266@1|root,COG1266@2|Bacteria,4P5RH@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS2_k127_5604948_1	643867.Ftrac_0354	1.858e-51	183.0	COG2824@1|root,COG2824@2|Bacteria,4NEFZ@976|Bacteroidetes,47QCE@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
CMS2_k127_5604948_0	1408813.AYMG01000020_gene2932	1.317e-74	255.0	COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,1IRWW@117747|Sphingobacteriia	976|Bacteroidetes	O	2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
CMS2_k127_5612753_7	1279009.ADICEAN_00473	6.228e-79	272.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47KVA@768503|Cytophagia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5612753_10	391603.FBALC1_08003	8.117e-74	261.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS2_k127_5612753_12	1239962.C943_00869	9.46e-60	212.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5M@976|Bacteroidetes,47QQ5@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
CMS2_k127_5612753_20	1313301.AUGC01000008_gene508	7.612e-24	105.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS2_k127_5612753_1	1124780.ANNU01000019_gene1733	3.541e-171	558.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47MTM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
CMS2_k127_5612753_9	1538644.KO02_07070	3.931e-77	263.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS2_k127_5612753_4	1237149.C900_04961	4.127e-113	371.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,47K0S@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS2_k127_5612753_0	1120965.AUBV01000001_gene3527	1e-323	996.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,47K4P@768503|Cytophagia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS2_k127_5612753_11	643867.Ftrac_1274	5.165e-61	218.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,47QV5@768503|Cytophagia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
CMS2_k127_5612753_14	1120965.AUBV01000001_gene3404	1.401e-54	193.0	2BXI1@1|root,32R1C@2|Bacteria,4NR9I@976|Bacteroidetes,47QU5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5612753_3	1237149.C900_04972	2.125e-138	447.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,47JR7@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS2_k127_5612753_17	880071.Fleli_3147	2.008e-46	170.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS2_k127_5612753_15	1121904.ARBP01000016_gene5251	1.638e-51	184.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,47QAX@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS2_k127_5612753_8	929562.Emtol_3992	1.349e-77	275.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS2_k127_5612753_13	1313421.JHBV01000005_gene4530	9.832e-60	216.0	COG1352@1|root,COG1352@2|Bacteria,4NFDS@976|Bacteroidetes,1IPVV@117747|Sphingobacteriia	976|Bacteroidetes	NT	PFAM MCP methyltransferase, CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS2_k127_5612753_21	1121904.ARBP01000011_gene1576	6.931e-19	94.0	28V38@1|root,2ZH6M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5612753_2	1313301.AUGC01000003_gene2111	1.37e-150	497.0	COG0643@1|root,COG0643@2|Bacteria,4NG31@976|Bacteroidetes	976|Bacteroidetes	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS2_k127_5612753_6	1121904.ARBP01000011_gene1578	1.356e-106	355.0	COG2201@1|root,COG2201@2|Bacteria,4NHMU@976|Bacteroidetes,47RD5@768503|Cytophagia	976|Bacteroidetes	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS2_k127_5612753_16	1121904.ARBP01000011_gene1579	2.277e-47	172.0	COG2197@1|root,COG2197@2|Bacteria,4PPMZ@976|Bacteroidetes	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_5612753_19	1121904.ARBP01000011_gene1580	5.55e-25	109.0	COG1871@1|root,COG1871@2|Bacteria	2|Bacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
CMS2_k127_5612753_18	1121904.ARBP01000011_gene1581	4.883e-44	166.0	COG0835@1|root,COG0835@2|Bacteria,4NTWG@976|Bacteroidetes,47RJU@768503|Cytophagia	976|Bacteroidetes	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS2_k127_5612753_5	1121904.ARBP01000011_gene1582	2.98e-111	370.0	COG0840@1|root,COG2202@1|root,COG0840@2|Bacteria,COG2202@2|Bacteria,4PI90@976|Bacteroidetes,47TC1@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5617577_26	1265503.KB905162_gene3610	2.854e-42	177.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5617577_38	313596.RB2501_04510	1.983e-05	58.0	2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
CMS2_k127_5617577_21	1122603.ATVI01000005_gene3497	9.19e-70	263.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5617577_33	1265503.KB905166_gene652	1.483e-21	104.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5617577_15	468059.AUHA01000003_gene1834	6.687e-162	531.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg,TPR_12,TPR_8
CMS2_k127_5617577_2	468059.AUHA01000003_gene1835	0.0	1231.0	COG1404@1|root,COG1404@2|Bacteria,4NHSQ@976|Bacteroidetes,1IWJ1@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS2_k127_5617577_37	746697.Aeqsu_2760	8.558e-06	59.0	2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
CMS2_k127_5617577_31	1122603.ATVI01000005_gene3497	3.321e-25	123.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5617577_9	313606.M23134_07119	8.08e-289	906.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,47Y3C@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5617577_28	1237149.C900_03225	1.378e-38	147.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,47RVQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
CMS2_k127_5617577_17	1317122.ATO12_06625	5.79e-148	477.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia,2YJ9Z@290174|Aquimarina	976|Bacteroidetes	E	Aminotransferase class-V	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_5617577_11	1237149.C900_04148	1.755e-209	665.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS2_k127_5617577_7	1237149.C900_04147	1.519e-309	968.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia	976|Bacteroidetes	G	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS2_k127_5617577_22	1237149.C900_00898	5.422e-69	243.0	2DGJB@1|root,32U7C@2|Bacteria,4NUFJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5617577_24	1237149.C900_04232	6.879e-53	189.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,47R94@768503|Cytophagia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS2_k127_5617577_14	1237149.C900_04233	5.911e-167	543.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,47JCU@768503|Cytophagia	976|Bacteroidetes	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS2_k127_5617577_29	1121859.KB890750_gene98	3.92e-32	126.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,47R7H@768503|Cytophagia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS2_k127_5617577_6	1237149.C900_04235	0.0	1029.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,47KTE@768503|Cytophagia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS2_k127_5617577_13	1237149.C900_04236	2.061e-170	536.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_5617577_16	1237149.C900_04237	1.406e-156	498.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,47JQX@768503|Cytophagia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_5617577_19	880070.Cycma_3135	3.418e-97	323.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47K51@768503|Cytophagia	976|Bacteroidetes	S	PFAM GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS2_k127_5617577_32	762903.Pedsa_3788	4.324e-23	106.0	2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,1ISA1@117747|Sphingobacteriia	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_5617577_10	643867.Ftrac_0843	4.446e-234	736.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,47JQ2@768503|Cytophagia	976|Bacteroidetes	E	PFAM glucose-methanol-choline oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
CMS2_k127_5617577_8	1237149.C900_05833	1.635e-293	922.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_5617577_23	1237149.C900_05832	6.783e-61	216.0	COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,47MWP@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
CMS2_k127_5617577_1	1237149.C900_05830	0.0	1308.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,47JQZ@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
CMS2_k127_5617577_4	1237149.C900_05827	0.0	1071.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,47JS9@768503|Cytophagia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS2_k127_5617577_5	1237149.C900_05835	0.0	1054.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,47MA2@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS2_k127_5617577_20	1279009.ADICEAN_00395	1.489e-80	271.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,47PC6@768503|Cytophagia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS2_k127_5617577_30	1237149.C900_05837	5.158e-26	108.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,47RYG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS2_k127_5617577_25	1237149.C900_05838	1.223e-52	188.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,47QDB@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS2_k127_5617577_12	926562.Oweho_1274	2.382e-183	599.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia,2PAGV@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS2_k127_5617577_18	1237149.C900_05504	5.049e-134	439.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,47JF5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS2_k127_5617577_27	643867.Ftrac_2576	4.702e-40	161.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,47KXV@768503|Cytophagia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CMS2_k127_5617577_0	1237149.C900_05507	0.0	1576.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia	976|Bacteroidetes	L	Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011
CMS2_k127_5617577_3	1237149.C900_02668	0.0	1164.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,47KK6@768503|Cytophagia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
CMS2_k127_5654218_32	643867.Ftrac_3626	1.299e-24	112.0	COG2909@1|root,COG2909@2|Bacteria,4PBPM@976|Bacteroidetes,47W4T@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
CMS2_k127_5654218_3	616991.JPOO01000001_gene3173	6.701e-273	887.0	COG2885@1|root,COG3291@1|root,COG5644@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,COG5644@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia	976|Bacteroidetes	DZ	TIGRFAM Bacterial surface protein 26-residue repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,DUF285,TIG,TSP_3
CMS2_k127_5654218_37	1469557.JSWF01000012_gene1201	2.706e-06	62.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	-	-	4.6.1.13	ko:K01771	ko00562,map00562	-	R03332	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Crystall,DUF1028,MAM,fn3
CMS2_k127_5654218_8	313606.M23134_01687	7.15e-162	515.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,47NGE@768503|Cytophagia	976|Bacteroidetes	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS2_k127_5654218_9	1123248.KB893321_gene480	1.003e-158	530.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_5654218_30	880070.Cycma_4319	1.307e-28	115.0	COG0053@1|root,COG0053@2|Bacteria,4NVGY@976|Bacteroidetes,47SZY@768503|Cytophagia	976|Bacteroidetes	P	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	MerC
CMS2_k127_5654218_28	471854.Dfer_1571	1.863e-33	144.0	28K2Q@1|root,2Z9S1@2|Bacteria,4NH0K@976|Bacteroidetes,47MG8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
CMS2_k127_5654218_12	1185876.BN8_00142	1.282e-133	443.0	COG0561@1|root,COG0561@2|Bacteria,4NFSF@976|Bacteroidetes,47MAQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	GO:0000272,GO:0001871,GO:0003674,GO:0005488,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0030246,GO:0030247,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_5654218_1	760192.Halhy_5557	0.0	1041.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1J0GI@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5654218_29	1121904.ARBP01000017_gene5107	8.173e-30	126.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyco_hydro_cc,Sigma70_r2,Sigma70_r4_2
CMS2_k127_5654218_22	234267.Acid_6568	4.409e-79	274.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_5654218_11	745718.JADT01000001_gene1669	3.426e-136	457.0	COG2849@1|root,COG2849@2|Bacteria,4NJB4@976|Bacteroidetes,1I0QY@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352,MORN_2
CMS2_k127_5654218_7	1237149.C900_05324	1.201e-163	523.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,47JIH@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS2_k127_5654218_4	641524.ADICYQ_4401	1.019e-221	694.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_5654218_35	391587.KAOT1_08829	1.814e-13	76.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5654218_24	1185876.BN8_01480	2.263e-74	253.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_5654218_20	1237149.C900_02547	2.695e-81	280.0	COG0589@1|root,COG0589@2|Bacteria,4NFSG@976|Bacteroidetes,47NF9@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_5654218_14	1237149.C900_02546	1.534e-127	417.0	COG1932@1|root,COG1932@2|Bacteria,4PKN4@976|Bacteroidetes,47J9A@768503|Cytophagia	976|Bacteroidetes	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS2_k127_5654218_2	1237149.C900_01327	5.538e-309	956.0	COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,47MQ2@768503|Cytophagia	976|Bacteroidetes	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
CMS2_k127_5654218_33	929703.KE386491_gene193	5.694e-23	104.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1,Rhodanese
CMS2_k127_5654218_13	1121904.ARBP01000010_gene2261	1.941e-130	436.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,47JS5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
CMS2_k127_5654218_18	1121904.ARBP01000003_gene6234	1.647e-93	320.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,47K5Z@768503|Cytophagia	976|Bacteroidetes	HQ	PFAM chorismate binding enzyme	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
CMS2_k127_5654218_26	1121904.ARBP01000006_gene3995	4.35e-48	175.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,47QEZ@768503|Cytophagia	976|Bacteroidetes	Q	PFAM thioesterase superfamily	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
CMS2_k127_5654218_23	1237149.C900_04753	2.638e-76	262.0	COG0406@1|root,COG0406@2|Bacteria,4NFX5@976|Bacteroidetes,47JSV@768503|Cytophagia	976|Bacteroidetes	G	phosphoglycerate mutase family	gpm	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS2_k127_5654218_16	1121011.AUCB01000011_gene1733	3.428e-105	347.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,1HYAH@117743|Flavobacteriia,23HUN@178469|Arenibacter	976|Bacteroidetes	S	Creatinine amidohydrolase	crnA	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS2_k127_5654218_15	655815.ZPR_4168	7.47e-121	404.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS2_k127_5654218_17	1122176.KB903543_gene466	5.367e-100	336.0	COG3608@1|root,COG3608@2|Bacteria,4NJRY@976|Bacteroidetes,1J09U@117747|Sphingobacteriia	976|Bacteroidetes	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS2_k127_5654218_31	649761.HMPREF0973_01409	1.917e-27	119.0	COG0115@1|root,COG0115@2|Bacteria,4NSFJ@976|Bacteroidetes,2FNQJ@200643|Bacteroidia	976|Bacteroidetes	EH	Psort location Cytoplasmic, score 8.96	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
CMS2_k127_5654218_19	1500281.JQKZ01000038_gene3129	3.356e-91	310.0	COG0147@1|root,COG0147@2|Bacteria,4NFKB@976|Bacteroidetes,1HX4G@117743|Flavobacteriia,3ZP2I@59732|Chryseobacterium	976|Bacteroidetes	EH	Aminobenzoate synthetase	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
CMS2_k127_5654218_10	313628.LNTAR_19822	2.465e-158	507.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yisS	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_5654218_6	485918.Cpin_7279	1.631e-189	596.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1IQDJ@117747|Sphingobacteriia	976|Bacteroidetes	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS2_k127_5654218_34	1237149.C900_01363	9.725e-22	99.0	2DZQQ@1|root,32VGE@2|Bacteria,4NYQ2@976|Bacteroidetes	976|Bacteroidetes	S	Transmembrane family 220, helix	-	-	-	-	-	-	-	-	-	-	-	-	TMEM220
CMS2_k127_5654218_21	1122225.AULQ01000001_gene1824	8.51e-81	277.0	COG0101@1|root,COG0101@2|Bacteria,4NG3N@976|Bacteroidetes,1HX0T@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS2_k127_5654218_25	1123400.KB904761_gene2508	3.233e-73	250.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
CMS2_k127_5654218_5	313603.FB2170_14638	1.369e-190	602.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,1HYBZ@117743|Flavobacteriia,2PG71@252356|Maribacter	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_5654218_27	1453500.AT05_03740	7.66e-47	176.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,1HZSP@117743|Flavobacteriia	976|Bacteroidetes	S	sialic acid o-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS2_k127_5654218_0	1237149.C900_04837	0.0	1530.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47N7Y@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS2_k127_5754535_1	1237149.C900_03550	1.447e-302	944.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47JBR@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS2_k127_5754535_7	643867.Ftrac_0033	3.852e-57	204.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,47Q9G@768503|Cytophagia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
CMS2_k127_5754535_5	643867.Ftrac_3473	4.161e-111	366.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,47JDP@768503|Cytophagia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS2_k127_5754535_6	1123276.KB893283_gene5128	2.173e-70	247.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS2_k127_5754535_4	926559.JoomaDRAFT_2065	1.686e-118	391.0	COG0696@1|root,COG0696@2|Bacteria,4PNG1@976|Bacteroidetes,1IKG8@117743|Flavobacteriia	976|Bacteroidetes	G	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
CMS2_k127_5754535_0	1120966.AUBU01000005_gene3809	0.0	1324.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes	976|Bacteroidetes	T	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6,Sortilin-Vps10
CMS2_k127_5754535_3	865937.Gilli_3208	6.063e-138	450.0	COG3385@1|root,COG3385@2|Bacteria,4NG39@976|Bacteroidetes,1HY95@117743|Flavobacteriia	976|Bacteroidetes	L	Pfam Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
CMS2_k127_5754535_2	1121904.ARBP01000008_gene3427	1.063e-201	655.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_585490_2	1500281.JQKZ01000009_gene3067	3.61e-27	112.0	2AWH3@1|root,31NDJ@2|Bacteria,4NRPZ@976|Bacteroidetes,1I4Y0@117743|Flavobacteriia,3ZSBB@59732|Chryseobacterium	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3
CMS2_k127_585490_0	1233950.IW22_07345	5.978e-118	383.0	COG3361@1|root,COG3361@2|Bacteria,4NFDT@976|Bacteroidetes,1I03M@117743|Flavobacteriia,3ZR58@59732|Chryseobacterium	976|Bacteroidetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
CMS2_k127_585490_1	269798.CHU_1869	3.671e-82	281.0	COG0500@1|root,COG2226@2|Bacteria,4NGMD@976|Bacteroidetes,47PNY@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS2_k127_585490_3	1392490.JHZX01000001_gene1142	6.113e-26	109.0	2AVPC@1|root,31MGE@2|Bacteria,4NQFW@976|Bacteroidetes,1I37U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5860063_1	886377.Murru_0969	3.411e-264	832.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,1HZJK@117743|Flavobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
CMS2_k127_5860063_0	1120966.AUBU01000012_gene70	1.191e-292	915.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_5860063_4	391596.PBAL39_10671	6.818e-65	229.0	COG0500@1|root,COG2226@2|Bacteria,4PM1K@976|Bacteroidetes,1IRV8@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS2_k127_5860063_2	1120968.AUBX01000015_gene3700	1.17e-225	721.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_5860063_7	1046627.BZARG_2276	1.173e-10	70.0	28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,1I3WF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5860063_5	1237149.C900_00803	2.546e-44	169.0	29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,47RB5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5860063_3	1237149.C900_00802	4.823e-198	644.0	COG4206@1|root,COG4206@2|Bacteria,4PKF2@976|Bacteroidetes,47JDS@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5860063_6	1313301.AUGC01000004_gene2226	8.703e-34	135.0	COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the Fur family	zur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS2_k127_5939733_0	643867.Ftrac_2449	0.0	1114.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,47KGB@768503|Cytophagia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
CMS2_k127_5939733_1	1237149.C900_01779	1.984e-231	720.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,47KFI@768503|Cytophagia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CMS2_k127_5939733_3	1237149.C900_01778	1.596e-29	123.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,47R9C@768503|Cytophagia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS2_k127_5939733_2	1237149.C900_01777	5.242e-124	405.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS2_k127_5939733_4	1313421.JHBV01000046_gene244	2.169e-11	72.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476
CMS2_k127_5953190_5	861299.J421_0649	5.624e-76	267.0	COG0596@1|root,COG0596@2|Bacteria	861299.J421_0649|-	S	hydrolase activity, acting on ester bonds	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
CMS2_k127_5953190_3	1121481.AUAS01000014_gene2321	6.048e-112	370.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,47M8V@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_5953190_4	1237149.C900_01428	3.959e-78	262.0	COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,47P72@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS2_k127_5953190_1	1046627.BZARG_1338	9.397e-299	926.0	COG2936@1|root,COG2936@2|Bacteria,4NHGT@976|Bacteroidetes,1HYGE@117743|Flavobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
CMS2_k127_5953190_8	1189612.A33Q_2600	1.117e-26	116.0	28KSE@1|root,2ZBRS@2|Bacteria,4NNCR@976|Bacteroidetes,47P8I@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_5953190_2	1380600.AUYN01000009_gene1076	6.654e-230	724.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1I7RS@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS2_k127_5953190_6	880070.Cycma_4469	1.005e-74	256.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PA8@768503|Cytophagia	976|Bacteroidetes	C	2Fe-2S -binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_5953190_0	1120965.AUBV01000010_gene2764	0.0	1069.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KPV@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_6144988_11	688270.Celal_2293	1.325e-71	256.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1I0Z6@117743|Flavobacteriia,1F9ZQ@104264|Cellulophaga	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_6144988_15	1237149.C900_02052	8.748e-67	232.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_6144988_14	1120966.AUBU01000006_gene3292	6.752e-68	234.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
CMS2_k127_6144988_7	1189612.A33Q_2320	6.385e-108	361.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,47KBG@768503|Cytophagia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS2_k127_6144988_17	1122605.KB893643_gene920	2.525e-64	233.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1IRSV@117747|Sphingobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
CMS2_k127_6144988_21	1185876.BN8_03528	1.696e-15	78.0	COG2608@1|root,COG2608@2|Bacteria,4NURN@976|Bacteroidetes,47SNP@768503|Cytophagia	976|Bacteroidetes	P	PFAM Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
CMS2_k127_6144988_1	1380384.JADN01000006_gene2438	1.638e-252	799.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS2_k127_6144988_12	1121904.ARBP01000049_gene4419	2.427e-70	242.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,47PX9@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_6144988_20	1237149.C900_03235	1.592e-36	143.0	2E5FG@1|root,33075@2|Bacteria,4NWB7@976|Bacteroidetes,47QE3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6144988_5	643867.Ftrac_1936	1.991e-124	405.0	COG1363@1|root,COG1363@2|Bacteria,4NH34@976|Bacteroidetes,47MR1@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS2_k127_6144988_0	411154.GFO_0327	3.188e-306	952.0	COG0155@1|root,COG1895@1|root,COG0155@2|Bacteria,COG1895@2|Bacteria,4NENW@976|Bacteroidetes,1HWQ6@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	sir	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr
CMS2_k127_6144988_8	991.IW20_06095	9.006e-92	308.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1HX5W@117743|Flavobacteriia,2NSQI@237|Flavobacterium	976|Bacteroidetes	H	Uroporphyrin-III C-methyltransferase	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CMS2_k127_6144988_13	1123234.AUKI01000013_gene1609	1.923e-69	240.0	COG1648@1|root,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,1HYI1@117743|Flavobacteriia	976|Bacteroidetes	H	COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
CMS2_k127_6144988_4	1004149.AFOE01000018_gene532	9.132e-155	495.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_6144988_19	1122179.KB890439_gene1629	2.03e-40	151.0	COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,1IU16@117747|Sphingobacteriia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	thcC	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS2_k127_6144988_6	1122225.AULQ01000012_gene487	2.58e-108	354.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1HYTC@117743|Flavobacteriia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS2_k127_6144988_10	1237149.C900_04310	3.787e-77	262.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_6144988_16	1237149.C900_04309	1.502e-64	224.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_6144988_3	1209072.ALBT01000024_gene3776	2.814e-182	582.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1FG89@10|Cellvibrio	1236|Gammaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854,ko:K19168	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000,ko02048	-	-	-	FGGY_C,FGGY_N
CMS2_k127_6144988_2	1121011.AUCB01000015_gene45	6.368e-229	715.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1HXW8@117743|Flavobacteriia,23G0V@178469|Arenibacter	976|Bacteroidetes	G	Catalyzes the interconversion of D-xylose to D-xylulose	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
CMS2_k127_6144988_9	555500.I215_03088	6.821e-86	289.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1HZ7M@117743|Flavobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_6144988_18	376686.Fjoh_1434	4.057e-48	196.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia,2NSPN@237|Flavobacterium	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M_N
CMS2_k127_6183750_0	330214.NIDE1715	2.476e-18	100.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat,VCBS
CMS2_k127_6191586_9	1237149.C900_01728	6.238e-21	94.0	COG2921@1|root,COG2921@2|Bacteria,4P9XR@976|Bacteroidetes,47S9P@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
CMS2_k127_6191586_1	1237149.C900_01727	1.736e-197	637.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,47KBN@768503|Cytophagia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
CMS2_k127_6191586_4	1237149.C900_01726	1.633e-157	507.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,47KQX@768503|Cytophagia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS2_k127_6191586_8	1237149.C900_01725	2.541e-43	164.0	COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes,47R6J@768503|Cytophagia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
CMS2_k127_6191586_6	643867.Ftrac_1016	4.579e-52	208.0	2EBR7@1|root,335R4@2|Bacteria,4P6KN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6191586_3	643867.Ftrac_1017	2.05e-188	609.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CMS2_k127_6191586_0	643867.Ftrac_1018	1.013e-208	696.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NMWW@976|Bacteroidetes,47SGQ@768503|Cytophagia	976|Bacteroidetes	L	SUPERFAMILY SSF53098, Polynucleotidyl transferase, Ribonuclease H fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974,NB-ARC,Sel1,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
CMS2_k127_6191586_2	388413.ALPR1_05020	5.572e-193	610.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_6191586_5	1120966.AUBU01000013_gene407	3.257e-68	234.0	2C88U@1|root,2ZAHP@2|Bacteria,4NK63@976|Bacteroidetes,47NBI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
CMS2_k127_6191586_7	1124780.ANNU01000005_gene2358	1.851e-44	166.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,47QBK@768503|Cytophagia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS2_k127_6194904_39	1250005.PHEL85_1741	3.072e-08	64.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI1V@976|Bacteroidetes,1HWSH@117743|Flavobacteriia,3VVIG@52959|Polaribacter	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
CMS2_k127_6194904_32	880070.Cycma_3016	8.458e-34	143.0	COG3325@1|root,COG3325@2|Bacteria,4NNUM@976|Bacteroidetes,47PUW@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
CMS2_k127_6194904_37	471854.Dfer_2908	3.099e-21	100.0	COG0526@1|root,COG0526@2|Bacteria,4NW95@976|Bacteroidetes	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin,Thioredoxin_8
CMS2_k127_6194904_8	1150600.ADIARSV_0073	2.9e-195	625.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
CMS2_k127_6194904_19	330214.NIDE3880	7.394e-107	353.0	COG2326@1|root,COG2326@2|Bacteria	2|Bacteria	S	polyphosphate kinase activity	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
CMS2_k127_6194904_31	1124780.ANNU01000066_gene387	3.12e-36	142.0	2DN0J@1|root,32UI3@2|Bacteria,4NT4U@976|Bacteroidetes,47R55@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6194904_9	1120965.AUBV01000007_gene2535	2.068e-190	599.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,47KCH@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
CMS2_k127_6194904_4	1124780.ANNU01000066_gene385	2.787e-239	752.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,47KI8@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS2_k127_6194904_15	1237149.C900_05645	6.157e-127	413.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47UAQ@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS2_k127_6194904_1	517418.Ctha_1886	8.384e-274	852.0	COG4147@1|root,COG4147@2|Bacteria,1FDIY@1090|Chlorobi	1090|Chlorobi	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS2_k127_6194904_36	1121012.AUKX01000005_gene3638	2.906e-30	121.0	COG4327@1|root,COG4327@2|Bacteria,4NSV7@976|Bacteroidetes,1I3X5@117743|Flavobacteriia,23HJ7@178469|Arenibacter	976|Bacteroidetes	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
CMS2_k127_6194904_35	1288963.ADIS_4617	5.285e-31	126.0	2E0TJ@1|root,32WB7@2|Bacteria,4NTAN@976|Bacteroidetes,47RC3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6194904_10	1120968.AUBX01000009_gene527	2.074e-186	589.0	COG2041@1|root,COG2041@2|Bacteria,4NEIQ@976|Bacteroidetes,47KB3@768503|Cytophagia	976|Bacteroidetes	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS2_k127_6194904_0	1237149.C900_01449	0.0	1077.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,47K1X@768503|Cytophagia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS2_k127_6194904_33	7739.XP_002589382.1	1.127e-31	139.0	COG4886@1|root,KOG0617@2759|Eukaryota,KOG0619@2759|Eukaryota,38E6Q@33154|Opisthokonta,3BE4G@33208|Metazoa,3D0J2@33213|Bilateria,483Q5@7711|Chordata	33154|Opisthokonta	KLT	maintenance of epithelial cell apical/basal polarity	-	-	-	-	-	-	-	-	-	-	-	-	Death,LRR_4,LRR_8,Pkinase,Pkinase_Tyr,TIR_2
CMS2_k127_6194904_28	643867.Ftrac_1186	5.122e-46	168.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS2_k127_6194904_7	1237149.C900_05079	3.397e-201	638.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,47K0W@768503|Cytophagia	976|Bacteroidetes	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
CMS2_k127_6194904_6	1237149.C900_05078	3.606e-202	647.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47JEK@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS2_k127_6194904_5	1237149.C900_05076	1.901e-227	707.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,47KQK@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_6194904_16	1121011.AUCB01000026_gene2923	9.12e-122	400.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1I009@117743|Flavobacteriia,23GV6@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_6194904_12	1237149.C900_03608	4.314e-174	556.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,47MPX@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS2_k127_6194904_24	1121904.ARBP01000007_gene2921	1.969e-69	248.0	COG2203@1|root,COG2203@2|Bacteria,4NICW@976|Bacteroidetes	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
CMS2_k127_6194904_29	1122179.KB890457_gene2083	1.82e-44	167.0	COG1416@1|root,COG1416@2|Bacteria,4NVVJ@976|Bacteroidetes,1IYQX@117747|Sphingobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS2_k127_6194904_25	1121904.ARBP01000019_gene2715	1.104e-62	243.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,4PNTS@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
CMS2_k127_6194904_20	1237149.C900_03719	2.771e-98	333.0	2CG1Y@1|root,2Z9QX@2|Bacteria,4NJI6@976|Bacteroidetes,47PFJ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS2_k127_6194904_13	1237149.C900_03717	1.707e-137	443.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS2_k127_6194904_2	385682.AFSL01000053_gene478	2.232e-247	774.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,2FMVI@200643|Bacteroidia,3XIUZ@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS2_k127_6194904_34	688270.Celal_0279	1.593e-31	128.0	COG3437@1|root,COG3437@2|Bacteria,4P49T@976|Bacteroidetes,1I2Y1@117743|Flavobacteriia,1F9GJ@104264|Cellulophaga	976|Bacteroidetes	T	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_6194904_23	643867.Ftrac_3702	2.709e-75	276.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,47XFA@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
CMS2_k127_6194904_27	643867.Ftrac_3471	4.188e-48	179.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_6194904_11	1237149.C900_01203	3.071e-186	590.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JS8@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS2_k127_6194904_22	1237149.C900_01202	3.92e-91	316.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PSU@768503|Cytophagia	976|Bacteroidetes	S	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS2_k127_6194904_14	1120965.AUBV01000010_gene2893	3.081e-133	431.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,47JZR@768503|Cytophagia	976|Bacteroidetes	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS2_k127_6194904_26	1237149.C900_04768	4.602e-56	198.0	COG1366@1|root,COG1366@2|Bacteria,4NTPB@976|Bacteroidetes,47R1F@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
CMS2_k127_6194904_18	1237149.C900_04769	1.072e-115	379.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,47KGX@768503|Cytophagia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS2_k127_6194904_21	1237149.C900_04770	5.338e-98	326.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,47J8X@768503|Cytophagia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS2_k127_6194904_3	1237149.C900_02470	9.903e-244	767.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47KHA@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS2_k127_6194904_38	1121904.ARBP01000007_gene2926	8.361e-12	75.0	COG2067@1|root,COG2067@2|Bacteria,4PK2U@976|Bacteroidetes,47QDY@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6194904_17	1237149.C900_02467	1.419e-120	401.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,47K9R@768503|Cytophagia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS2_k127_6194904_30	1123234.AUKI01000016_gene3010	2.179e-36	145.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS2_k127_6194904_40	443143.GM18_0341	2.283e-05	49.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6195204_1	643867.Ftrac_2196	0.000686	44.0	28KMN@1|root,2ZA61@2|Bacteria,4NJ9P@976|Bacteroidetes,47P0N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062
CMS2_k127_6195204_0	1237149.C900_04423	3.579e-263	817.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes,47NKP@768503|Cytophagia	976|Bacteroidetes	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS2_k127_6197688_28	1237149.C900_04554	2.265e-45	166.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,47JE2@768503|Cytophagia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS2_k127_6197688_11	1288963.ADIS_1163	1.022e-175	559.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_6197688_31	1237149.C900_05678	4.008e-35	136.0	COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,47XZ0@768503|Cytophagia	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS2_k127_6197688_9	1237149.C900_04306	4.882e-218	685.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS2_k127_6197688_2	1121859.KB890738_gene3041	4.412e-268	843.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,47JK7@768503|Cytophagia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
CMS2_k127_6197688_36	1121904.ARBP01000077_gene4901	5.622e-17	96.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_6197688_39	1121904.ARBP01000022_gene3498	3.138e-07	64.0	COG1520@1|root,COG5276@1|root,COG1520@2|Bacteria,COG5276@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS2_k127_6197688_8	313596.RB2501_16209	4.093e-235	732.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,1HZDE@117743|Flavobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_6197688_26	929703.KE386491_gene3568	4.572e-58	227.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,47P5E@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
CMS2_k127_6197688_38	469595.CSAG_00308	4.022e-12	68.0	COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,1S2F9@1236|Gammaproteobacteria,3WXAW@544|Citrobacter	1236|Gammaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	ybcI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
CMS2_k127_6197688_1	1296416.JACB01000031_gene2572	5e-324	1017.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia,2YGWZ@290174|Aquimarina	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_6197688_14	153721.MYP_4598	7.267e-167	539.0	COG0318@1|root,COG0318@2|Bacteria,4NM3E@976|Bacteroidetes,47K5A@768503|Cytophagia	976|Bacteroidetes	IQ	AMP-binding enzyme	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
CMS2_k127_6197688_20	714943.Mucpa_6225	6.157e-93	315.0	COG1247@1|root,COG1247@2|Bacteria,4NPQH@976|Bacteroidetes,1IXNQ@117747|Sphingobacteriia	976|Bacteroidetes	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6197688_35	1158294.JOMI01000001_gene1841	3.27e-19	88.0	COG1670@1|root,COG1670@2|Bacteria,4NN0F@976|Bacteroidetes,2FWSX@200643|Bacteroidia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS2_k127_6197688_10	1408473.JHXO01000009_gene3261	1.876e-192	603.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,2FYMX@200643|Bacteroidia	976|Bacteroidetes	C	Malate/L-lactate dehydrogenase	-	-	1.1.1.130	ko:K08092	ko00040,ko00053,map00040,map00053	-	R02637,R02639	RC00238	ko00000,ko00001,ko01000	-	-	-	Ldh_2
CMS2_k127_6197688_16	1237149.C900_05167	9.715e-124	404.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,47N7G@768503|Cytophagia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6197688_30	1237149.C900_05166	4.333e-41	160.0	28MYR@1|root,32XFW@2|Bacteria,4NUHA@976|Bacteroidetes,47RQ0@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_6197688_3	1237149.C900_03188	4.94e-261	816.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,47M0I@768503|Cytophagia	976|Bacteroidetes	P	Voltage gated chloride channel	clcB	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS2_k127_6197688_24	1124780.ANNU01000018_gene1633	4.267e-62	220.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,47QBX@768503|Cytophagia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
CMS2_k127_6197688_23	643867.Ftrac_1853	1.275e-70	245.0	COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes,47RE3@768503|Cytophagia	976|Bacteroidetes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CMS2_k127_6197688_27	1189612.A33Q_4297	3.569e-51	187.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,47R6S@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
CMS2_k127_6197688_33	760192.Halhy_4452	3.223e-32	131.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1ISIF@117747|Sphingobacteriia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CMS2_k127_6197688_5	1121904.ARBP01000032_gene1999	5.146e-250	779.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,47KHI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS2_k127_6197688_19	1124780.ANNU01000030_gene1155	9.387e-110	377.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
CMS2_k127_6197688_15	1124780.ANNU01000030_gene1156	1.11e-132	446.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
CMS2_k127_6197688_17	860228.Ccan_08420	1.237e-112	374.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1HWX7@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS2_k127_6197688_25	1237149.C900_01722	1.027e-60	217.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K36@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS2_k127_6197688_22	1237149.C900_01723	3.306e-89	310.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,47N37@768503|Cytophagia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6197688_18	1237149.C900_01724	3.284e-112	376.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,47MJ6@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS2_k127_6197688_37	649349.Lbys_2161	3.486e-13	77.0	COG1564@1|root,COG1564@2|Bacteria,4NGJH@976|Bacteroidetes,47MV1@768503|Cytophagia	976|Bacteroidetes	H	thiamine pyrophosphokinase	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
CMS2_k127_6197688_21	1237149.C900_02789	1.326e-90	305.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,47MAX@768503|Cytophagia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
CMS2_k127_6197688_6	1380600.AUYN01000006_gene429	2.456e-247	781.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS2_k127_6197688_12	376686.Fjoh_3990	2.244e-171	550.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1HY99@117743|Flavobacteriia,2NSKP@237|Flavobacterium	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_6197688_29	1480694.DC28_03655	5.843e-42	163.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	MA20_22965	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_6197688_13	1237149.C900_00688	3.438e-171	542.0	COG3177@1|root,COG3177@2|Bacteria,4NSD2@976|Bacteroidetes,47TWH@768503|Cytophagia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Penicillinase_R
CMS2_k127_6197688_0	143224.JQMD01000002_gene1787	0.0	1066.0	COG2755@1|root,COG4244@1|root,COG2755@2|Bacteria,COG4244@2|Bacteria,4NG6K@976|Bacteroidetes,1HZ9V@117743|Flavobacteriia	976|Bacteroidetes	E	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS2_k127_6197688_4	616991.JPOO01000001_gene3217	1.755e-259	806.0	COG3119@1|root,COG3119@2|Bacteria,4NGYE@976|Bacteroidetes,1I7XZ@117743|Flavobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS2_k127_6197688_7	1168034.FH5T_18050	1.209e-246	771.0	COG3177@1|root,COG3177@2|Bacteria,4NG08@976|Bacteroidetes	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
CMS2_k127_6197688_34	1121481.AUAS01000018_gene444	1.712e-27	113.0	COG3668@1|root,COG3668@2|Bacteria,4NW7E@976|Bacteroidetes,47S0X@768503|Cytophagia	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CMS2_k127_6197688_42	1121481.AUAS01000018_gene445	1.025e-05	51.0	2A95X@1|root,30YAH@2|Bacteria,4PC26@976|Bacteroidetes,47WPU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6197688_40	445961.IW15_01785	8.651e-07	59.0	2DV4I@1|root,33U08@2|Bacteria,4P2GF@976|Bacteroidetes,1I8KC@117743|Flavobacteriia,3ZPPP@59732|Chryseobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4919)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4919
CMS2_k127_6241777_16	1123278.KB893388_gene5716	1.581e-69	238.0	COG2080@1|root,COG2080@2|Bacteria,4NPUP@976|Bacteroidetes,47KVH@768503|Cytophagia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_6241777_0	760192.Halhy_2824	0.0	1327.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,1IV5J@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS2_k127_6241777_13	760192.Halhy_2825	1.1e-86	295.0	COG1319@1|root,COG1319@2|Bacteria,4NE3W@976|Bacteroidetes,1IUZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS2_k127_6241777_9	700598.Niako_0794	2.517e-119	390.0	COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes,1IW0P@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ATPase associated with various cellular activities AAA_3	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS2_k127_6241777_15	760192.Halhy_2471	2.894e-77	272.0	COG3552@1|root,COG3552@2|Bacteria,4NKWF@976|Bacteroidetes,1IW0S@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS2_k127_6241777_1	1122176.KB903609_gene5178	7.306e-279	869.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IPSM@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS2_k127_6241777_10	1232410.KI421425_gene1541	3.252e-118	388.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria,43S6E@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	acuI	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS2_k127_6241777_17	1279009.ADICEAN_00322	4.198e-52	188.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,47QBC@768503|Cytophagia	2|Bacteria	S	FeS assembly SUF system protein	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
CMS2_k127_6241777_11	1237149.C900_04823	3.806e-100	332.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,47VWV@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
CMS2_k127_6241777_18	1237149.C900_04822	1.469e-48	180.0	COG3460@1|root,COG3460@2|Bacteria	2|Bacteria	Q	phenylacetate catabolic process	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
CMS2_k127_6241777_5	1237149.C900_04821	1.862e-186	585.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,47TVD@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
CMS2_k127_6241777_8	1237149.C900_01872	9.097e-151	484.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,47MDN@768503|Cytophagia	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS2_k127_6241777_14	525373.HMPREF0766_11214	4.912e-83	279.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1IQ0S@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS2_k127_6241777_3	926549.KI421517_gene739	2.601e-225	705.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,47JAE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS2_k127_6241777_6	555500.I215_02528	6.57e-170	541.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,1HX9B@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS2_k127_6241777_7	1121904.ARBP01000007_gene2943	9.619e-163	527.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6241777_4	1121904.ARBP01000026_gene635	2.701e-201	649.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
CMS2_k127_6241777_2	1249997.JHZW01000003_gene2060	1.32e-234	731.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,1I081@117743|Flavobacteriia,2PGR4@252356|Maribacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
CMS2_k127_6241777_19	1380600.AUYN01000007_gene3408	2.056e-31	135.0	COG2801@1|root,COG2801@2|Bacteria,4NTJY@976|Bacteroidetes,1I37S@117743|Flavobacteriia	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
CMS2_k127_6241777_20	1121904.ARBP01000066_gene2210	6.832e-19	96.0	COG1876@1|root,COG3209@1|root,COG1876@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	cwlK	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,DUF2809,PG_binding_1,Peptidase_M15_4,VanY
CMS2_k127_6241777_22	929704.Myrod_3214	1.041e-07	59.0	2ABZD@1|root,311GW@2|Bacteria,4PGAH@976|Bacteroidetes,1I6UK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6241777_12	1124780.ANNU01000035_gene293	6.048e-93	317.0	COG2133@1|root,COG3209@1|root,COG2133@2|Bacteria,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,47KAA@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6248958_8	1232410.KI421413_gene485	3.429e-83	280.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria,43UFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS2_k127_6248958_9	1237149.C900_04190	1.432e-82	287.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,47PQF@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
CMS2_k127_6248958_0	1237149.C900_04189	0.0	1311.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,47K30@768503|Cytophagia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS2_k127_6248958_13	1237149.C900_01235	5.97e-58	214.0	2EG6T@1|root,339YP@2|Bacteria,4NXNK@976|Bacteroidetes,47T48@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6248958_12	1237149.C900_01234	1.255e-61	218.0	2C093@1|root,34BBZ@2|Bacteria,4P53B@976|Bacteroidetes,47VVT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6248958_2	1237149.C900_01230	3.289e-213	687.0	COG1629@1|root,COG4771@2|Bacteria,4PKKT@976|Bacteroidetes,47KRF@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CMS2_k127_6248958_7	1237149.C900_01229	2.834e-102	336.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,47N3P@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS2_k127_6248958_5	1279009.ADICEAN_01972	5.02e-110	375.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,47KS3@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS2_k127_6248958_17	641524.ADICYQ_5620	1.32e-10	70.0	298K1@1|root,2ZVQX@2|Bacteria,4NNNX@976|Bacteroidetes,47Q8A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6248958_14	929562.Emtol_3721	3.746e-23	106.0	COG0135@1|root,COG0135@2|Bacteria,4NMKY@976|Bacteroidetes,47PJ8@768503|Cytophagia	976|Bacteroidetes	E	isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS2_k127_6248958_1	1237149.C900_00028	1.048e-239	759.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CMS2_k127_6248958_6	1237149.C900_00026	7.682e-109	359.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6248958_11	1237149.C900_04349	1.405e-62	239.0	COG0457@1|root,COG0457@2|Bacteria,4PJN4@976|Bacteroidetes,47NZ0@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6248958_10	1237149.C900_04036	9.322e-82	288.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
CMS2_k127_6248958_4	313606.M23134_07780	1.331e-146	477.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_6248958_3	1237149.C900_04039	1.22e-172	565.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NWV@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_624978_0	192952.MM_2345	4.688e-215	677.0	COG3666@1|root,arCOG03514@2157|Archaea,2Y5BN@28890|Euryarchaeota,2NBF1@224756|Methanomicrobia	224756|Methanomicrobia	L	Transposase DDE domain	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
CMS2_k127_6419824_0	290512.Paes_2385	1.691e-79	272.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_6419824_2	1191523.MROS_0493	8.329e-13	75.0	2EJN9@1|root,33DD4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6419824_1	1150621.SMUL_0722	8.338e-16	83.0	2BYFY@1|root,33EM6@2|Bacteria,1NIAK@1224|Proteobacteria,432Y1@68525|delta/epsilon subdivisions,2YSQQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_642526_6	1120966.AUBU01000019_gene275	1.697e-17	82.0	COG1396@1|root,COG1396@2|Bacteria,4NWG8@976|Bacteroidetes,47STE@768503|Cytophagia	976|Bacteroidetes	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_642526_8	1120966.AUBU01000019_gene275	0.0009222	42.0	COG1396@1|root,COG1396@2|Bacteria,4NWG8@976|Bacteroidetes,47STE@768503|Cytophagia	976|Bacteroidetes	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_642526_5	762903.Pedsa_0334	2.777e-38	145.0	COG2026@1|root,COG2026@2|Bacteria,4NW0W@976|Bacteroidetes,1IU0G@117747|Sphingobacteriia	976|Bacteroidetes	DJ	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	RelE
CMS2_k127_642526_2	1121104.AQXH01000006_gene2332	1.302e-102	345.0	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes,1IYDP@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_642526_0	1237149.C900_02066	3.942e-163	526.0	COG0076@1|root,COG0076@2|Bacteria,4NGZB@976|Bacteroidetes	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS2_k127_642526_4	1237149.C900_04570	7.903e-49	176.0	COG0599@1|root,COG0599@2|Bacteria,4NNPC@976|Bacteroidetes,47QDA@768503|Cytophagia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS2_k127_642526_1	1237149.C900_04571	3.064e-146	471.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,47KUF@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
CMS2_k127_642526_3	1237149.C900_04572	1.756e-98	326.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,47JII@768503|Cytophagia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS2_k127_6449767_2	1313301.AUGC01000005_gene263	3.439e-163	523.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes	976|Bacteroidetes	O	Collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CMS2_k127_6449767_6	1237149.C900_04318	1.869e-16	81.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes,47SE5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CMS2_k127_6449767_4	1237149.C900_00017	1.736e-144	467.0	COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,47P9V@768503|Cytophagia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
CMS2_k127_6449767_1	1237149.C900_00018	0.0	1346.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47NPA@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS2_k127_6449767_3	1237149.C900_00020	4.982e-157	507.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,47RSG@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_6449767_0	1237149.C900_05488	0.0	1935.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
CMS2_k127_6449767_5	1124780.ANNU01000008_gene2666	3.458e-121	397.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_6461090_33	1408473.JHXO01000005_gene1655	1.19e-09	60.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS2_k127_6461090_25	1121104.AQXH01000001_gene1497	3.089e-37	153.0	COG4538@1|root,COG4538@2|Bacteria,4PKKQ@976|Bacteroidetes	976|Bacteroidetes	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SnoaL_2
CMS2_k127_6461090_2	649349.Lbys_0664	3.475e-260	807.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_6461090_12	1237149.C900_02193	5.251e-153	490.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS2_k127_6461090_21	1237149.C900_02192	1.783e-45	176.0	2BPYJ@1|root,32ISF@2|Bacteria,4NRVJ@976|Bacteroidetes,47QN3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6461090_15	1237149.C900_02191	2.141e-136	439.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS2_k127_6461090_32	643867.Ftrac_0404	4.189e-12	71.0	2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes,47SN3@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
CMS2_k127_6461090_10	1124780.ANNU01000024_gene3094	1.492e-171	566.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,47KJ6@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
CMS2_k127_6461090_13	1237149.C900_02185	3.492e-145	462.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,47JJC@768503|Cytophagia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS2_k127_6461090_3	1237149.C900_02184	1.188e-257	798.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,47JFB@768503|Cytophagia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CMS2_k127_6461090_16	1237149.C900_02183	3.285e-119	392.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,47J9Z@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS2_k127_6461090_11	643867.Ftrac_3535	7.252e-155	500.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,47JI5@768503|Cytophagia	976|Bacteroidetes	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
CMS2_k127_6461090_4	1237149.C900_02181	2.828e-253	789.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,47KVF@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
CMS2_k127_6461090_26	153721.MYP_3795	5.705e-36	141.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,47RDS@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised P-loop hydrolase UPF0079	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS2_k127_6461090_9	1237149.C900_02179	1.72e-187	594.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47J94@768503|Cytophagia	976|Bacteroidetes	E	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS2_k127_6461090_1	1313301.AUGC01000003_gene2158	0.0	1219.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS2_k127_6461090_8	1286632.P278_20460	3.005e-198	629.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS2_k127_6461090_5	1237149.C900_04904	3.468e-212	665.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,47KTT@768503|Cytophagia	976|Bacteroidetes	Q	fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
CMS2_k127_6461090_20	1237149.C900_03604	6.478e-61	220.0	COG2067@1|root,COG2067@2|Bacteria,4NVCH@976|Bacteroidetes,47SCX@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS2_k127_6461090_19	643867.Ftrac_0923	4.901e-80	269.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia	976|Bacteroidetes	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
CMS2_k127_6461090_24	313590.MED134_04904	1.169e-41	159.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I37G@117743|Flavobacteriia,37F1D@326319|Dokdonia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS2_k127_6461090_7	880071.Fleli_4001	2.153e-202	657.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
CMS2_k127_6461090_22	1121011.AUCB01000007_gene1381	7.404e-45	173.0	COG4632@1|root,COG4632@2|Bacteria,4NQZB@976|Bacteroidetes,1IIJ0@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
CMS2_k127_6461090_0	1121904.ARBP01000018_gene2599	0.0	1324.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,47MI0@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
CMS2_k127_6461090_18	643867.Ftrac_0458	3.959e-104	345.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,47N85@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
CMS2_k127_6461090_17	391596.PBAL39_06336	1.821e-104	349.0	COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes,1IQA4@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_6461090_35	1122603.ATVI01000005_gene3497	1.081e-08	57.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6461090_6	1484460.JSWG01000011_gene1711	9.875e-210	664.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CMS2_k127_6461090_31	376686.Fjoh_4389	8.88e-13	70.0	2D2Z4@1|root,32TDX@2|Bacteria,4NVF7@976|Bacteroidetes,1I5X1@117743|Flavobacteriia,2NXA3@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
CMS2_k127_6461090_30	163908.KB235896_gene262	5.679e-13	79.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,1G2VV@1117|Cyanobacteria,1HQES@1161|Nostocales	1117|Cyanobacteria	Q	Laminin G domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS2_k127_6461090_34	926562.Oweho_1412	6.787e-09	58.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CMS2_k127_6461090_27	1343739.PAP_07515	4.581e-29	127.0	arCOG09492@1|root,arCOG09492@2157|Archaea,2Y3AH@28890|Euryarchaeota,244X9@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6461090_29	332101.JIBU02000041_gene1447	4.559e-18	90.0	COG1846@1|root,COG1846@2|Bacteria,1VJ5F@1239|Firmicutes,24RS1@186801|Clostridia,36NZ3@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS2_k127_6461090_23	1279009.ADICEAN_02091	2.73e-44	164.0	COG4068@1|root,COG4068@2|Bacteria,4NR5U@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
CMS2_k127_6461090_14	641526.ADIWIN_0320	2.502e-144	468.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
CMS2_k127_6546761_6	1237149.C900_01970	2.167e-43	164.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS2_k127_6546761_5	1121957.ATVL01000006_gene2981	7.273e-81	278.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6546761_1	1237149.C900_03312	8.446e-223	699.0	COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,47NRN@768503|Cytophagia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS2_k127_6546761_4	1237149.C900_03318	7.725e-99	328.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_6546761_7	643867.Ftrac_3124	5.797e-32	138.0	COG2335@1|root,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS2_k127_6546761_3	1122176.KB903541_gene235	5.279e-134	434.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,1IYDA@117747|Sphingobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS2_k127_6546761_2	1237149.C900_05610	1.29e-150	484.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,47KY6@768503|Cytophagia	976|Bacteroidetes	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	dmpP	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS2_k127_6546761_0	1237149.C900_05611	4.952e-250	784.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS2_k127_6595073_6	1121898.Q766_12485	4.028e-120	389.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,1HZHQ@117743|Flavobacteriia,2NVH2@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_6595073_3	1313301.AUGC01000017_gene795	1.92e-161	524.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes	976|Bacteroidetes	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS2_k127_6595073_10	485918.Cpin_0162	7.924e-94	325.0	COG1119@1|root,COG1119@2|Bacteria,4NEWY@976|Bacteroidetes,1INTA@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
CMS2_k127_6595073_11	926549.KI421517_gene1917	6.47e-74	256.0	COG2755@1|root,COG2755@2|Bacteria,4NMUB@976|Bacteroidetes,47P6Y@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS2_k127_6595073_2	1121904.ARBP01000004_gene830	4.043e-207	661.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,47M73@768503|Cytophagia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CMS2_k127_6595073_17	1121373.KB903640_gene3754	1.18e-38	156.0	COG2017@1|root,COG2017@2|Bacteria,4NKUK@976|Bacteroidetes,47KGR@768503|Cytophagia	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS2_k127_6595073_8	1121904.ARBP01000001_gene5464	5.592e-96	318.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,47JCH@768503|Cytophagia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS2_k127_6595073_4	1237149.C900_05675	1.029e-147	477.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS2_k127_6595073_5	1237149.C900_05673	1.14e-132	434.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,47KVD@768503|Cytophagia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS2_k127_6595073_0	382464.ABSI01000012_gene2022	1.219e-313	983.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,46S9M@74201|Verrucomicrobia,2IVIZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CJ	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS2_k127_6595073_12	1158338.JNLJ01000001_gene915	3.428e-61	222.0	COG0123@1|root,COG0123@2|Bacteria,2G3QH@200783|Aquificae	200783|Aquificae	BQ	PFAM histone deacetylase superfamily	acuC2	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS2_k127_6595073_7	1237149.C900_00267	4.112e-104	343.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,47JE4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS2_k127_6595073_15	1237149.C900_00268	2.833e-55	200.0	COG0241@1|root,COG0241@2|Bacteria,4NNDD@976|Bacteroidetes,47QM8@768503|Cytophagia	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
CMS2_k127_6595073_9	1237149.C900_01608	7.371e-95	317.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS2_k127_6595073_16	1279009.ADICEAN_01198	1.002e-50	193.0	COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS2_k127_6595073_14	1185876.BN8_02367	8.345e-57	205.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_6595073_1	1237149.C900_00619	7.034e-292	905.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,47MRU@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
CMS2_k127_6595073_13	1237149.C900_00618	5.416e-60	210.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,47PAF@768503|Cytophagia	976|Bacteroidetes	G	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS2_k127_6672434_7	1237149.C900_04608	1.233e-187	615.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
CMS2_k127_6672434_9	926549.KI421517_gene1502	9.154e-172	555.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS2_k127_6672434_8	1237149.C900_05642	3.447e-172	544.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,47JAR@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS2_k127_6672434_18	1237149.C900_01196	4.198e-87	291.0	COG1595@1|root,COG1595@2|Bacteria,4NX8R@976|Bacteroidetes,47PIG@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF,Sigma70_r2
CMS2_k127_6672434_27	1237149.C900_04074	5.467e-22	99.0	COG3093@1|root,COG3093@2|Bacteria,4PC9U@976|Bacteroidetes,47X26@768503|Cytophagia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
CMS2_k127_6672434_11	1237149.C900_03263	3.017e-153	496.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia	976|Bacteroidetes	C	PFAM Class III cytochrome C family	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
CMS2_k127_6672434_0	1237149.C900_03264	0.0	1347.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
CMS2_k127_6672434_3	1237149.C900_03265	3.714e-276	851.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS2_k127_6672434_17	1237149.C900_03266	3.262e-87	290.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,47K4U@768503|Cytophagia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase membrane protein	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS2_k127_6672434_21	1237149.C900_03267	5.445e-72	248.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,47PEX@768503|Cytophagia	976|Bacteroidetes	C	PFAM Cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_6672434_6	1237149.C900_03268	1.361e-200	632.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,47JUF@768503|Cytophagia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6672434_12	1237149.C900_03269	6.331e-133	432.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,47JF8@768503|Cytophagia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CMS2_k127_6672434_2	1237149.C900_03270	0.0	1064.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,47JBQ@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS2_k127_6672434_13	1237149.C900_03272	1.409e-124	405.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS2_k127_6672434_20	1239962.C943_00688	8.755e-74	252.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,47NS2@768503|Cytophagia	976|Bacteroidetes	C	PFAM cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS2_k127_6672434_15	761193.Runsl_2973	2.07e-116	377.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,47JVP@768503|Cytophagia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS2_k127_6672434_26	1237149.C900_03275	7.311e-29	119.0	COG5605@1|root,COG5605@2|Bacteria,4NTVI@976|Bacteroidetes,47R14@768503|Cytophagia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
CMS2_k127_6672434_19	1237149.C900_03407	2.587e-83	286.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CMS2_k127_6672434_23	1237149.C900_03405	7.976e-65	232.0	COG0589@1|root,COG0589@2|Bacteria,4NQZP@976|Bacteroidetes,47Q8P@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_6672434_14	1237149.C900_03404	2.432e-120	404.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
CMS2_k127_6672434_4	1237149.C900_01975	5.268e-240	753.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47KUQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS2_k127_6672434_25	1237149.C900_01977	5.563e-33	135.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_6672434_22	1121904.ARBP01000005_gene4739	6.12e-71	264.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
CMS2_k127_6672434_1	1380600.AUYN01000009_gene1868	0.0	1124.0	COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4PNA4@976|Bacteroidetes,1IK7X@117743|Flavobacteriia	976|Bacteroidetes	CG	Trehalose utilisation	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
CMS2_k127_6672434_29	926549.KI421517_gene2850	2.031e-17	93.0	COG1629@1|root,COG1629@2|Bacteria,4PP8J@976|Bacteroidetes,47YJ2@768503|Cytophagia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_6672434_5	1237149.C900_02626	1.304e-231	728.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	paaN	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS2_k127_6672434_16	1237149.C900_02624	1.382e-96	321.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,47P85@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
CMS2_k127_6672434_10	1120965.AUBV01000001_gene3186	8.662e-154	496.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia	976|Bacteroidetes	S	CinA-like protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS2_k127_6695344_1	926551.KB900715_gene2201	2.218e-06	51.0	2DFVK@1|root,2ZTBH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6695344_0	643867.Ftrac_0248	2.763e-48	183.0	COG1470@1|root,COG3209@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,47MBZ@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,TSP_3
CMS2_k127_6696579_5	926549.KI421517_gene2894	1.092e-112	376.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,47MDG@768503|Cytophagia	976|Bacteroidetes	M	PFAM 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS2_k127_6696579_6	1237149.C900_03736	3.394e-108	359.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,47JC5@768503|Cytophagia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CMS2_k127_6696579_20	866536.Belba_3086	3.364e-05	50.0	2ERUU@1|root,33JE1@2|Bacteria,4NZ11@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6696579_2	1120965.AUBV01000013_gene1356	1.097e-177	572.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CMS2_k127_6696579_3	1408473.JHXO01000002_gene3859	1.312e-174	553.0	COG0667@1|root,COG0667@2|Bacteria,4NHA1@976|Bacteroidetes,2FPYX@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_6696579_7	867900.Celly_3055	2.707e-95	320.0	28IGK@1|root,2Z8I1@2|Bacteria,4NP5T@976|Bacteroidetes,1I756@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6696579_12	1123278.KB893581_gene978	8.049e-35	141.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_6696579_14	761193.Runsl_1949	2.459e-21	102.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_6696579_0	1121011.AUCB01000007_gene1247	2.731e-317	983.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_6696579_19	1123248.KB893319_gene4001	1.457e-08	59.0	COG0657@1|root,COG0657@2|Bacteria,4NKQT@976|Bacteroidetes,1IVD0@117747|Sphingobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS2_k127_6696579_16	745718.JADT01000017_gene1043	4.184e-20	96.0	2C3QT@1|root,32YUW@2|Bacteria,4NWNZ@976|Bacteroidetes,1I6M5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6696579_4	1237149.C900_00367	1.208e-154	494.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,47JH0@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS2_k127_6696579_8	1123057.P872_08935	8.828e-92	315.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,47MJP@768503|Cytophagia	976|Bacteroidetes	E	Putative serine dehydratase domain	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS2_k127_6696579_18	1484460.JSWG01000004_gene2667	3.909e-10	69.0	2E7ZY@1|root,332EA@2|Bacteria,4NX22@976|Bacteroidetes,1I5B0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6696579_15	1236508.BAKF01000024_gene1764	1.554e-20	95.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,2FSYQ@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS2_k127_6696579_9	1237149.C900_00242	1.981e-59	214.0	COG3599@1|root,COG3599@2|Bacteria,4NQDF@976|Bacteroidetes,47QRC@768503|Cytophagia	976|Bacteroidetes	D	TIGRFAM DivIVA domain	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
CMS2_k127_6696579_10	1239962.C943_00002	8.481e-58	212.0	COG2319@1|root,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,47JUN@768503|Cytophagia	976|Bacteroidetes	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS2_k127_6696579_13	1124780.ANNU01000030_gene1161	1.367e-32	137.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,47RPQ@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
CMS2_k127_6696579_17	1120968.AUBX01000009_gene524	2.304e-13	77.0	COG0526@1|root,COG0526@2|Bacteria,4NSUU@976|Bacteroidetes,47R9W@768503|Cytophagia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_6696579_1	1189612.A33Q_0734	8.756e-242	756.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,47MUV@768503|Cytophagia	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS2_k127_6717236_5	1127692.HMPREF9075_01034	2.642e-148	490.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,1ER6Z@1016|Capnocytophaga	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS2_k127_6717236_3	1168034.FH5T_01490	2.379e-261	824.0	COG1208@1|root,COG1208@2|Bacteria,4NGYR@976|Bacteroidetes,2FMJ4@200643|Bacteroidia	976|Bacteroidetes	JM	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
CMS2_k127_6717236_6	1168034.FH5T_01495	1.338e-48	187.0	COG1595@1|root,COG2202@1|root,COG1595@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF4157,HATPase_c,PAS,PAS_3,PAS_9,SatD,Sigma70_r2
CMS2_k127_6717236_1	1121481.AUAS01000001_gene4791	0.0	1071.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47YD7@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CMS2_k127_6717236_4	1434325.AZQN01000003_gene2617	1.64e-152	498.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,47JQF@768503|Cytophagia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_6717236_2	1189612.A33Q_1584	1.837e-305	970.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47M08@768503|Cytophagia	976|Bacteroidetes	S	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
CMS2_k127_6717236_0	1279009.ADICEAN_03159	0.0	1084.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47MGE@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
CMS2_k127_6717236_7	1237149.C900_02559	3.315e-09	61.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,47JY4@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
CMS2_k127_6814167_7	1237149.C900_01754	5.642e-109	354.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,47JVI@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS2_k127_6814167_13	1123073.KB899244_gene186	1.339e-12	79.0	COG1470@1|root,COG3209@1|root,COG5184@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,1N55D@1224|Proteobacteria,1T481@1236|Gammaproteobacteria,1XD8U@135614|Xanthomonadales	135614|Xanthomonadales	DMZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
CMS2_k127_6814167_12	1341155.FSS13T_07760	6.216e-16	86.0	28JHY@1|root,2Z9BE@2|Bacteria,4NGKG@976|Bacteroidetes,1I1EX@117743|Flavobacteriia,2NSJW@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6814167_9	641524.ADICYQ_2353	8.951e-55	199.0	2E7UT@1|root,3329Q@2|Bacteria,4NUQ3@976|Bacteroidetes,47SB3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6814167_11	880071.Fleli_1503	3.182e-33	135.0	COG4969@1|root,COG4969@2|Bacteria,4NVUE@976|Bacteroidetes,47WY3@768503|Cytophagia	976|Bacteroidetes	NU	Belongs to the N-Me-Phe pilin family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6814167_3	929703.KE386491_gene2315	7.926e-165	529.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,47JIU@768503|Cytophagia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS2_k127_6814167_6	714943.Mucpa_5541	3.151e-135	439.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1IP7N@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS2_k127_6814167_8	313594.PI23P_07145	1.743e-57	209.0	COG1414@1|root,COG1414@2|Bacteria,4NHTZ@976|Bacteroidetes,1I3H4@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K13641,ko:K19333	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
CMS2_k127_6814167_5	1122176.KB903587_gene4462	7.872e-146	470.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1IPQV@117747|Sphingobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CMS2_k127_6814167_4	313598.MED152_12754	2.809e-156	503.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,3VVVU@52959|Polaribacter	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS2_k127_6814167_1	1237149.C900_03232	2.571e-249	781.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,47JWD@768503|Cytophagia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS2_k127_6814167_2	1237149.C900_03231	4.98e-190	601.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,47JAB@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS2_k127_6814167_14	1166018.FAES_4827	1.044e-10	72.0	2DBER@1|root,2Z8TN@2|Bacteria,4NK2P@976|Bacteroidetes,47P45@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6814167_0	1123234.AUKI01000011_gene1102	1.6e-250	784.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HXMU@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_6814167_10	1121904.ARBP01000019_gene2715	3.64e-46	175.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,4PNTS@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
CMS2_k127_6860142_0	63737.Npun_R0801	3.878e-150	490.0	COG3385@1|root,COG3385@2|Bacteria,1GQDD@1117|Cyanobacteria	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6860142_1	344747.PM8797T_10619	4.588e-26	117.0	2BHNJ@1|root,32BRF@2|Bacteria,2J3N6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6895612_1	1237149.C900_05842	2.34e-267	852.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47NIF@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
CMS2_k127_6895612_11	1237149.C900_05843	1.62e-45	175.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47QIE@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_6895612_12	643867.Ftrac_3781	4.112e-41	153.0	2DIAB@1|root,302ID@2|Bacteria,4P6WW@976|Bacteroidetes,47WND@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6895612_13	643867.Ftrac_3780	4.223e-27	112.0	2EIHU@1|root,33C96@2|Bacteria,4NY5F@976|Bacteroidetes,47SZZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
CMS2_k127_6895612_3	1121904.ARBP01000010_gene2284	1.458e-117	381.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,47JWX@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS2_k127_6895612_2	388413.ALPR1_12890	2.213e-139	454.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,47K0F@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CMS2_k127_6895612_6	1237149.C900_03416	3.379e-88	295.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,47JY6@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS2_k127_6895612_0	760192.Halhy_4486	9.171e-268	846.0	COG1449@1|root,COG1449@2|Bacteria,4NFKK@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
CMS2_k127_6895612_10	1121875.KB907549_gene1942	1.982e-63	226.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,1HWW1@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS2_k127_6895612_7	926556.Echvi_3720	3.041e-78	265.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,47JY5@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS2_k127_6895612_5	929562.Emtol_4113	1.385e-113	388.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,47K4G@768503|Cytophagia	976|Bacteroidetes	M	COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_6895612_4	1237149.C900_00003	2.142e-114	374.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,47JCR@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_6895612_9	1189612.A33Q_0928	9.244e-69	242.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,47JZ5@768503|Cytophagia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS2_k127_6895612_8	313596.RB2501_04115	2.422e-71	244.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS2_k127_6961516_3	869213.JCM21142_400	2.356e-30	132.0	2D6WA@1|root,32TMZ@2|Bacteria,4NU16@976|Bacteroidetes,47VUX@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS2_k127_6961516_0	1408473.JHXO01000016_gene1934	2.291e-147	482.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FR8P@200643|Bacteroidia	976|Bacteroidetes	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS2_k127_6961516_2	1408473.JHXO01000016_gene1933	1.772e-88	297.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,2FT12@200643|Bacteroidia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS2_k127_6961516_1	313606.M23134_01800	9.075e-137	441.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47TXK@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_7092318_1	886377.Murru_0595	4.563e-288	891.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HZ5E@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_7092318_5	616991.JPOO01000001_gene4417	1.962e-155	499.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1I0IH@117743|Flavobacteriia,23FZZ@178469|Arenibacter	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS2_k127_7092318_3	1144313.PMI10_02675	2.699e-257	799.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,1HYCR@117743|Flavobacteriia,2NT4Q@237|Flavobacterium	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
CMS2_k127_7092318_6	926559.JoomaDRAFT_2659	4.524e-135	431.0	COG0235@1|root,COG0235@2|Bacteria,4NGMP@976|Bacteroidetes,1HYQV@117743|Flavobacteriia	976|Bacteroidetes	G	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS2_k127_7092318_2	1121887.AUDK01000018_gene3286	8.93e-279	865.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,1HZHT@117743|Flavobacteriia,2NSRX@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CMS2_k127_7092318_0	1250232.JQNJ01000001_gene512	5.477e-314	972.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IIHD@117743|Flavobacteriia	976|Bacteroidetes	S	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
CMS2_k127_7092318_7	398720.MED217_11589	3.62e-15	76.0	COG3507@1|root,COG3507@2|Bacteria,4NFU3@976|Bacteroidetes,1HYQR@117743|Flavobacteriia,2XK4V@283735|Leeuwenhoekiella	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
CMS2_k127_7092318_8	1121898.Q766_05685	4.36e-06	52.0	COG3507@1|root,COG3507@2|Bacteria,4NIHD@976|Bacteroidetes,1I86D@117743|Flavobacteriia,2NTQQ@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	GH43_C,Glyco_hydro_43
CMS2_k127_7092318_4	926559.JoomaDRAFT_2665	2.587e-253	789.0	COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,1HZE1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CMS2_k127_753632_4	1120965.AUBV01000012_gene1394	3.168e-19	92.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
CMS2_k127_753632_1	641524.ADICYQ_2310	7.772e-90	305.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,47PK2@768503|Cytophagia	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
CMS2_k127_753632_0	1189612.A33Q_3279	3.177e-120	436.0	COG1352@1|root,COG2201@1|root,COG2202@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,47XZS@768503|Cytophagia	976|Bacteroidetes	T	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
CMS2_k127_753632_2	926549.KI421517_gene3764	2.889e-71	248.0	COG1192@1|root,COG1192@2|Bacteria,4NGFE@976|Bacteroidetes,47NCJ@768503|Cytophagia	976|Bacteroidetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS2_k127_753632_3	1184267.A11Q_309	3.479e-43	164.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2MTRS@213481|Bdellovibrionales,2WIX9@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,dCache_1,sCache_2
CMS2_k127_777594_14	1111730.ATTM01000002_gene1204	1.081e-37	143.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia,2NUSC@237|Flavobacterium	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
CMS2_k127_777594_12	1123008.KB905692_gene243	4.387e-51	184.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,2FYF3@200643|Bacteroidia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS2_k127_777594_1	1237149.C900_00490	4.564e-256	794.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47JS2@768503|Cytophagia	976|Bacteroidetes	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS2_k127_777594_11	1249997.JHZW01000002_gene708	4.136e-60	211.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2PHD4@252356|Maribacter	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS2_k127_777594_3	1237149.C900_03179	2.23e-117	392.0	COG0402@1|root,COG0402@2|Bacteria,4NG64@976|Bacteroidetes,47UD9@768503|Cytophagia	976|Bacteroidetes	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_777594_16	1278307.KB906970_gene1073	1.459e-12	74.0	2FHFB@1|root,3499D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_777594_7	1121373.KB903635_gene871	5.748e-85	293.0	COG0451@1|root,COG0451@2|Bacteria,4NKKZ@976|Bacteroidetes,47XKD@768503|Cytophagia	976|Bacteroidetes	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS2_k127_777594_10	1121904.ARBP01000002_gene6688	4.901e-68	239.0	COG1349@1|root,COG1349@2|Bacteria,4NI1F@976|Bacteroidetes,47MTV@768503|Cytophagia	976|Bacteroidetes	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
CMS2_k127_777594_8	1237149.C900_04550	4.821e-82	280.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,47KUT@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_777594_4	1237149.C900_03750	5.592e-115	374.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS2_k127_777594_9	1237149.C900_03751	5.438e-70	244.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,47PC8@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_777594_5	926562.Oweho_1690	5.515e-107	351.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia,2PAN0@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_777594_13	996306.SSUR61_0289	7.075e-40	154.0	COG0454@1|root,COG0456@2|Bacteria,1VDFK@1239|Firmicutes,4HMHW@91061|Bacilli,1WSB3@1307|Streptococcus suis	91061|Bacilli	K	Acetyltransferase (GNAT) domain	XK27_03150	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS2_k127_777594_6	1123008.KB905695_gene2543	2.748e-90	304.0	COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,2FM31@200643|Bacteroidia,22WGI@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS2_k127_777594_2	1123008.KB905695_gene2544	8.844e-138	449.0	COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,2FN24@200643|Bacteroidia,22WMQ@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_777594_0	1121930.AQXG01000001_gene1592	4.009e-300	939.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IP3R@117747|Sphingobacteriia	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CMS2_k127_777594_15	1343739.PAP_06500	1.964e-19	89.0	COG1476@1|root,arCOG01864@2157|Archaea,2Y089@28890|Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
CMS2_k127_802343_4	760192.Halhy_0605	1.126e-64	226.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1IT6C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CMS2_k127_802343_3	1121012.AUKX01000010_gene1995	4.737e-132	448.0	COG1073@1|root,COG2755@1|root,COG1073@2|Bacteria,COG2755@2|Bacteria,4NG53@976|Bacteroidetes,1I165@117743|Flavobacteriia,23H3Z@178469|Arenibacter	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Peptidase_S9
CMS2_k127_802343_2	1237149.C900_01118	5.833e-174	556.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,47JDH@768503|Cytophagia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS2_k127_802343_1	1237149.C900_01117	2.227e-188	594.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS2_k127_802343_0	1237149.C900_01115	1.408e-255	795.0	COG0318@1|root,COG0318@2|Bacteria,4NDYR@976|Bacteroidetes,47JUW@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS2_k127_802343_5	1237149.C900_01969	7.832e-44	170.0	COG3291@1|root,COG3291@2|Bacteria,4NV3K@976|Bacteroidetes,47W7K@768503|Cytophagia	976|Bacteroidetes	C	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_90931_3	1237149.C900_04800	0.0004156	47.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,47JQQ@768503|Cytophagia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_90931_2	925409.KI911562_gene2727	7.751e-52	190.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS2_k127_90931_0	616991.JPOO01000003_gene988	2.603e-150	482.0	COG4123@1|root,COG4123@2|Bacteria,4NGDY@976|Bacteroidetes,1HZFW@117743|Flavobacteriia,23FUP@178469|Arenibacter	976|Bacteroidetes	S	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS2_k127_90931_1	398720.MED217_01150	6.735e-67	234.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,1HWP4@117743|Flavobacteriia,2XJU9@283735|Leeuwenhoekiella	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS2_k127_946024_3	1267535.KB906767_gene4776	2.978e-32	132.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria,2JMQ5@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_946024_4	388413.ALPR1_02245	2.431e-24	120.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,47P48@768503|Cytophagia	976|Bacteroidetes	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_7,TPR_8
CMS2_k127_946024_2	1384056.N787_03775	3.656e-36	158.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,1T5R6@1236|Gammaproteobacteria,1XDGT@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4
CMS2_k127_946024_5	1121929.KB898665_gene2674	7.043e-13	73.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,4HAF7@91061|Bacilli,4702W@74385|Gracilibacillus	91061|Bacilli	KT	helix_turn_helix, arabinose operon control protein	tctD	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
CMS2_k127_946024_0	1519464.HY22_02010	5.762e-121	397.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N,Peptidase_S8
CMS2_k127_946024_1	1237149.C900_05679	2.696e-119	391.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47N8Q@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS2_k127_981901_4	573413.Spirs_1821	1.452e-41	164.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,2J6N2@203691|Spirochaetes	203691|Spirochaetes	NT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	cheA-1	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS2_k127_981901_5	1121413.JMKT01000011_gene2372	2.59e-37	143.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,42SAC@68525|delta/epsilon subdivisions,2WP7J@28221|Deltaproteobacteria,2MBHN@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	cheY34H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS2_k127_981901_1	926549.KI421517_gene3764	3.97e-57	207.0	COG1192@1|root,COG1192@2|Bacteria,4NGFE@976|Bacteroidetes,47NCJ@768503|Cytophagia	976|Bacteroidetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS2_k127_981901_0	1279009.ADICEAN_00853	2.805e-97	339.0	COG0840@1|root,COG0840@2|Bacteria,4NIJR@976|Bacteroidetes,47XEI@768503|Cytophagia	976|Bacteroidetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
CMS2_k127_981901_3	391603.FBALC1_00807	6.464e-45	173.0	2DBBT@1|root,2Z8AC@2|Bacteria,4NIRZ@976|Bacteroidetes,1HZMZ@117743|Flavobacteriia	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS2_k127_981901_2	153721.MYP_4869	2.835e-49	181.0	COG0835@1|root,COG0835@2|Bacteria,4NTK7@976|Bacteroidetes,47X59@768503|Cytophagia	976|Bacteroidetes	NT	Two component signalling adaptor domain	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
## 3534 queries scanned
## Total time (seconds): 135.9213047027588
## Rate: 26.00 q/s