## Sat Nov  9 01:00:23 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS2_bin.66.fa -m mmseqs --itype genome -o CMS2_bin.66 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS2_bin.66 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS2_k127_1023427_2	313596.RB2501_05180	0.000752	48.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded DNA-binding protein	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS2_k127_1023427_1	313596.RB2501_05185	1.53e-287	888.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HYK4@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS2_k127_1023427_0	313596.RB2501_05195	0.0	1301.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_1024728_0	929562.Emtol_1587	1.673e-187	593.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47NB7@768503|Cytophagia	976|Bacteroidetes	CH	FAD binding domain	-	-	1.14.13.218	ko:K20940	ko00405,ko01130,map00405,map01130	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS2_k127_1024728_2	929562.Emtol_1586	3.383e-73	250.0	2DMP1@1|root,32SS8@2|Bacteria,4NQY9@976|Bacteroidetes,47QNE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
CMS2_k127_1024728_1	929562.Emtol_1585	8.597e-170	542.0	COG0477@1|root,COG2814@2|Bacteria,4NI75@976|Bacteroidetes,47M13@768503|Cytophagia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4,Sugar_tr
CMS2_k127_1036733_1	313596.RB2501_14994	5.022e-121	401.0	COG0111@1|root,COG0111@2|Bacteria,4NE9J@976|Bacteroidetes,1HZ5Z@117743|Flavobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
CMS2_k127_1036733_2	313596.RB2501_14999	1.497e-56	202.0	28PYW@1|root,2ZCID@2|Bacteria,4NN0N@976|Bacteroidetes,1I1ED@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1036733_0	313596.RB2501_15004	4.201e-167	527.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HZ5R@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_1037175_1	313596.RB2501_03310	4.645e-159	506.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
CMS2_k127_1037175_3	313596.RB2501_03305	2.001e-39	151.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1I40T@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CMS2_k127_1037175_0	313596.RB2501_03300	5.167e-241	752.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,1HY1A@117743|Flavobacteriia	976|Bacteroidetes	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS2_k127_1037175_2	313596.RB2501_03295	3.939e-111	364.0	COG2267@1|root,COG2267@2|Bacteria,4PKJZ@976|Bacteroidetes,1IJBC@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS2_k127_1037175_4	313596.RB2501_03290	4.304e-16	78.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1HX38@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS2_k127_1043864_1	313596.RB2501_10287	2.128e-23	101.0	28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1HZAP@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
CMS2_k127_1043864_0	404380.Gbem_3669	1.781e-122	405.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42MEY@68525|delta/epsilon subdivisions,2WM0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS2_k127_1064151_8	313596.RB2501_00961	8.39e-100	327.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,1IIHC@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS2_k127_1064151_9	313596.RB2501_00951	3.692e-53	190.0	COG3350@1|root,COG3350@2|Bacteria,4NRFU@976|Bacteroidetes,1I3FC@117743|Flavobacteriia	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CMS2_k127_1064151_0	313596.RB2501_00941	0.0	1705.0	COG3250@1|root,COG3408@1|root,COG3250@2|Bacteria,COG3408@2|Bacteria,4NESP@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS2_k127_1064151_2	313596.RB2501_00936	3.37e-273	844.0	COG1457@1|root,COG1457@2|Bacteria,4NHHC@976|Bacteroidetes,1HX92@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1064151_3	313596.RB2501_00931	6.617e-216	673.0	COG1304@1|root,COG1304@2|Bacteria,4NEBK@976|Bacteroidetes,1HXKE@117743|Flavobacteriia	976|Bacteroidetes	C	Dehydrogenase	lldD	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
CMS2_k127_1064151_5	313596.RB2501_00926	3.451e-181	577.0	COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes,1HYQ6@117743|Flavobacteriia	976|Bacteroidetes	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
CMS2_k127_1064151_4	313596.RB2501_00921	3.465e-203	640.0	COG4952@1|root,COG4952@2|Bacteria,4NFWW@976|Bacteroidetes,1HYPA@117743|Flavobacteriia	976|Bacteroidetes	M	sugar isomerase	-	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	-
CMS2_k127_1064151_1	313596.RB2501_00916	0.0	1219.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,4NEM0@976|Bacteroidetes,1HXU6@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
CMS2_k127_1064151_6	313596.RB2501_00911	5.227e-173	547.0	COG1609@1|root,COG1725@1|root,COG1609@2|Bacteria,COG1725@2|Bacteria,4NFB7@976|Bacteroidetes,1HYFS@117743|Flavobacteriia	976|Bacteroidetes	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
CMS2_k127_1064151_7	1185876.BN8_03209	7.889e-165	534.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NIKG@976|Bacteroidetes,47MEK@768503|Cytophagia	976|Bacteroidetes	C	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH
CMS2_k127_1084745_0	313596.RB2501_11527	6.347e-270	841.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS2_k127_1084745_1	313596.RB2501_11532	3.528e-131	423.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrophosphatase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
CMS2_k127_1084745_2	313596.RB2501_11537	3.34e-93	310.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1HXAF@117743|Flavobacteriia	976|Bacteroidetes	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS2_k127_1084915_0	313596.RB2501_04255	0.0	1447.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
CMS2_k127_1084915_4	1348583.ATLH01000029_gene1458	3.163e-68	239.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1I17W@117743|Flavobacteriia,1F961@104264|Cellulophaga	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS2_k127_1084915_3	313596.RB2501_04240	1.6e-77	262.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1I17F@117743|Flavobacteriia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS2_k127_1084915_1	1121875.KB907550_gene788	2.309e-303	959.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K02305,ko:K08738	ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00529,M00595	R00294,R10151	RC02794,RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.10,3.D.4.6	-	-	Cytochrom_C,HEAT_2
CMS2_k127_1084915_2	313596.RB2501_04235	5.65e-110	357.0	COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,1I079@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_1089069_1	313596.RB2501_02935	2.318e-198	622.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1HY3E@117743|Flavobacteriia	976|Bacteroidetes	G	phosphorylase	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
CMS2_k127_1089069_0	313596.RB2501_13019	6.083e-202	637.0	COG0205@1|root,COG0205@2|Bacteria,4NKKM@976|Bacteroidetes,1HZSD@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS2_k127_1089069_3	313596.RB2501_02940	4.804e-57	207.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1I2XZ@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1089069_2	313596.RB2501_02945	1.199e-68	234.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1HYAM@117743|Flavobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1095032_1	864702.OsccyDRAFT_4275	1.439e-26	121.0	COG2267@1|root,COG2267@2|Bacteria,1GQMB@1117|Cyanobacteria	1117|Cyanobacteria	I	TIGRFAM proline-specific peptidases, Bacillus coagulans-type subfamily	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS2_k127_1095032_0	502347.ESCAB7627_0579	2.344e-57	207.0	COG0363@1|root,COG0363@2|Bacteria,1R8UH@1224|Proteobacteria,1RY0A@1236|Gammaproteobacteria,3XNZ8@561|Escherichia	1236|Gammaproteobacteria	G	galactosamine-6-phosphate isomerase activity	agaI	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016853,GO:0016860,GO:0016861,GO:0043877,GO:0044424,GO:0044444,GO:0044464	-	ko:K02080	ko00052,map00052	-	R08365	RC00163	ko00000,ko00001,ko01000	-	-	iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979	Glucosamine_iso
CMS2_k127_1095032_2	1121957.ATVL01000012_gene839	8.615e-12	64.0	2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,47QYD@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_1105974_1	1121875.KB907547_gene3089	1.496e-114	372.0	COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,1HYTU@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
CMS2_k127_1105974_0	313596.RB2501_08625	3.129e-183	583.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1HWY6@117743|Flavobacteriia	976|Bacteroidetes	S	Flavoprotein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS2_k127_1105974_2	313596.RB2501_08620	7.683e-111	364.0	COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,1HYHS@117743|Flavobacteriia	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS2_k127_1129010_8	1250232.JQNJ01000001_gene173	7.562e-65	228.0	COG0500@1|root,COG2226@2|Bacteria,4NHAE@976|Bacteroidetes,1HYTJ@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS2_k127_1129010_4	313596.RB2501_00301	1.437e-170	539.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia	976|Bacteroidetes	M	Murein transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS2_k127_1129010_5	313596.RB2501_00306	1.976e-102	337.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
CMS2_k127_1129010_9	1121875.KB907546_gene2811	5.954e-49	177.0	COG2388@1|root,COG2388@2|Bacteria,4NVBP@976|Bacteroidetes,1I41N@117743|Flavobacteriia	976|Bacteroidetes	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
CMS2_k127_1129010_1	313596.RB2501_00316	2.518e-231	721.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS2_k127_1129010_2	313596.RB2501_00321	2.524e-197	620.0	COG1208@1|root,COG1208@2|Bacteria,4PM6W@976|Bacteroidetes,1IJJT@117743|Flavobacteriia	976|Bacteroidetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,NTP_transf_4
CMS2_k127_1129010_10	1348583.ATLH01000011_gene386	3.77e-43	158.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1I3YC@117743|Flavobacteriia,1F9IH@104264|Cellulophaga	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL31 family	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS2_k127_1129010_6	313596.RB2501_00336	2.35e-70	245.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,1I2ZA@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
CMS2_k127_1129010_3	313596.RB2501_00341	2.184e-177	559.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1HXT8@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_1129010_0	313596.RB2501_00351	1.23e-301	931.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1HXUQ@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS2_k127_1129010_7	313596.RB2501_00356	1.449e-67	233.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS2_k127_1142443_1	313606.M23134_06801	3.825e-112	381.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,47Y1Q@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_1142443_0	1185876.BN8_04279	1.23e-196	623.0	COG2072@1|root,COG2072@2|Bacteria,4NKS6@976|Bacteroidetes,47MF8@768503|Cytophagia	976|Bacteroidetes	P	Flavin-binding monooxygenase-like	hapE	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_3
CMS2_k127_1142443_2	391603.FBALC1_03312	2.257e-30	123.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS2_k127_117284_3	1250005.PHEL85_3026	1.036e-07	53.0	COG0296@1|root,COG0296@2|Bacteria,4NSTP@976|Bacteroidetes,1I4C7@117743|Flavobacteriia,3VWNK@52959|Polaribacter	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
CMS2_k127_117284_0	313596.RB2501_03235	9.331e-134	435.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,1HZ16@117743|Flavobacteriia	976|Bacteroidetes	E	selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_117284_1	313596.RB2501_03240	4.478e-41	163.0	COG0262@1|root,COG0262@2|Bacteria,4NTP8@976|Bacteroidetes,1I3X6@117743|Flavobacteriia	976|Bacteroidetes	H	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
CMS2_k127_117284_2	313596.RB2501_03245	1.645e-35	138.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
CMS2_k127_118933_2	313596.RB2501_12809	1.208e-60	210.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia	976|Bacteroidetes	FJ	Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CMS2_k127_118933_1	985255.APHJ01000054_gene2128	2.106e-91	311.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1HX36@117743|Flavobacteriia,2P5N6@244698|Gillisia	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS2_k127_118933_0	313596.RB2501_12794	3.114e-157	498.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HY58@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS2_k127_1216516_3	313596.RB2501_15269	1.501e-30	124.0	2CJFR@1|root,32SKT@2|Bacteria,4NTS6@976|Bacteroidetes,1I4KT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1216516_2	313596.RB2501_15274	1.841e-62	221.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1I30V@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS2_k127_1216516_1	143224.JQMD01000002_gene766	4.255e-93	306.0	COG1522@1|root,COG1522@2|Bacteria,4NHG9@976|Bacteroidetes,1HXEQ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS2_k127_1216516_0	313596.RB2501_15284	2.559e-104	347.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_121768_0	313596.RB2501_01605	8.287e-303	935.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS2_k127_121768_3	1270193.JARP01000005_gene3681	3.311e-92	320.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,1HXB9@117743|Flavobacteriia,2NT88@237|Flavobacterium	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS2_k127_121768_5	313596.RB2501_01595	2.953e-40	155.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1I5AD@117743|Flavobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CMS2_k127_121768_2	313596.RB2501_01590	2.204e-100	330.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1HXSB@117743|Flavobacteriia	976|Bacteroidetes	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS2_k127_121768_4	313596.RB2501_01585	2.166e-48	178.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1I30B@117743|Flavobacteriia	976|Bacteroidetes	I	Biotin carboxyl carrier protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
CMS2_k127_121768_1	313596.RB2501_01580	2.329e-179	569.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1HXNP@117743|Flavobacteriia	976|Bacteroidetes	I	Biotin carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS2_k127_1238406_3	313596.RB2501_15184	8.288e-72	244.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS2_k127_1238406_0	313596.RB2501_15179	4.677e-167	528.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
CMS2_k127_1238406_1	313596.RB2501_15174	5.285e-131	422.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_1238406_2	313596.RB2501_15169	5.114e-76	262.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_125779_2	143224.JQMD01000002_gene3647	5.114e-44	161.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_125779_1	313596.RB2501_04195	2.179e-230	720.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS2_k127_125779_0	313596.RB2501_04200	8.936e-232	724.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1HXW7@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase family 109	nagA	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_125779_3	313596.RB2501_04205	7.4e-30	119.0	COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,1IJB4@117743|Flavobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
CMS2_k127_1258269_2	266748.HY04_10940	6.409e-106	352.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia,3ZR2A@59732|Chryseobacterium	976|Bacteroidetes	T	Bacterial regulatory proteins, crp family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
CMS2_k127_1258269_6	886377.Murru_1325	1.113e-16	85.0	2CED8@1|root,32YZ6@2|Bacteria,4NVDS@976|Bacteroidetes,1I5AZ@117743|Flavobacteriia	976|Bacteroidetes	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
CMS2_k127_1258269_4	313603.FB2170_00375	5.827e-38	146.0	COG4980@1|root,COG4980@2|Bacteria,4NRSE@976|Bacteroidetes,1I46Y@117743|Flavobacteriia,2PIS4@252356|Maribacter	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS2_k127_1258269_3	641524.ADICYQ_4478	1.155e-55	203.0	COG1595@1|root,COG1595@2|Bacteria,4NGYM@976|Bacteroidetes	976|Bacteroidetes	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
CMS2_k127_1258269_5	616991.JPOO01000001_gene4483	1.244e-36	142.0	2CBAQ@1|root,32U2I@2|Bacteria,4NTIM@976|Bacteroidetes,1I3ZJ@117743|Flavobacteriia,23HJ6@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1258269_1	313596.RB2501_09610	4.036e-165	528.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,1HYDJ@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CMS2_k127_1258269_0	313596.RB2501_09605	0.0	1162.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
CMS2_k127_1268322_3	313596.RB2501_04190	9.489e-57	200.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_1268322_0	313596.RB2501_04185	2.275e-244	760.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,1HZG2@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_1268322_1	143224.JQMD01000002_gene3655	4.178e-208	653.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,1HWJT@117743|Flavobacteriia	976|Bacteroidetes	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CMS2_k127_1268322_2	313596.RB2501_04180	2.874e-94	316.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,1HXIX@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome c biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CMS2_k127_1268322_4	313596.RB2501_04175	9.261e-47	171.0	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,1I2TV@117743|Flavobacteriia	976|Bacteroidetes	P	cytochrome cbb3 oxidase maturation protein CcoH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
CMS2_k127_1275763_0	313596.RB2501_15504	0.0	1569.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
CMS2_k127_1275763_1	313596.RB2501_15499	3.454e-99	327.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1HX2Z@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS2_k127_1275763_2	313596.RB2501_12682	8.075e-20	88.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1HXCC@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS2_k127_1277791_5	313596.RB2501_01650	2.984e-21	93.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_1277791_2	886377.Murru_0257	1.159e-73	259.0	COG3021@1|root,COG3021@2|Bacteria,4PKDH@976|Bacteroidetes,1HYUN@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS2_k127_1277791_3	313596.RB2501_01640	4.014e-37	142.0	2C9TE@1|root,32RPW@2|Bacteria,4NSGI@976|Bacteroidetes,1I446@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1277791_1	313596.RB2501_01635	3.212e-81	275.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,1I2IW@117743|Flavobacteriia	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
CMS2_k127_1277791_0	313596.RB2501_01630	2.591e-318	979.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1HY4X@117743|Flavobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS2_k127_1277791_4	616991.JPOO01000001_gene3709	1.707e-28	115.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia,23H1Z@178469|Arenibacter	976|Bacteroidetes	E	Dihydrodipicolinate reductase, C-terminus	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS2_k127_128434_1	886377.Murru_0822	8.875e-246	763.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS2_k127_128434_3	313596.RB2501_09185	3.069e-119	387.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,1HX10@117743|Flavobacteriia	976|Bacteroidetes	S	Methanol dehydrogenase	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS2_k127_128434_6	641524.ADICYQ_3304	4.349e-21	98.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,47QCD@768503|Cytophagia	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
CMS2_k127_128434_4	1250232.JQNJ01000001_gene735	1.674e-109	356.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1HXSV@117743|Flavobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS2_k127_128434_5	313596.RB2501_09200	4.323e-59	205.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1I2UP@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS2_k127_128434_2	313596.RB2501_09205	3.292e-191	599.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HX46@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase, M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_128434_0	313596.RB2501_09210	0.0	1356.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS2_k127_1322025_0	313596.RB2501_03735	2.408e-191	597.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CMS2_k127_1322025_2	313596.RB2501_03740	8.658e-72	246.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1I2U1@117743|Flavobacteriia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS2_k127_1322025_1	313596.RB2501_03745	2.288e-155	496.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,1HWM6@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS2_k127_134757_1	1249975.JQLP01000005_gene621	3.041e-106	348.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1HZDH@117743|Flavobacteriia,2P5C5@244698|Gillisia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_134757_0	1392498.JQLH01000001_gene2627	6.172e-168	538.0	28JFD@1|root,2Z99B@2|Bacteria,4NFQJ@976|Bacteroidetes,1IEQR@117743|Flavobacteriia,2PIM4@252356|Maribacter	976|Bacteroidetes	S	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
CMS2_k127_134757_2	313596.RB2501_14954	5.574e-36	139.0	COG2304@1|root,COG2304@2|Bacteria,4NI4I@976|Bacteroidetes,1HZMV@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS2_k127_1348328_7	143224.JQMD01000002_gene3198	4.538e-14	71.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia	976|Bacteroidetes	C	Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS2_k127_1348328_4	313596.RB2501_06605	2.16e-103	342.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS2_k127_1348328_0	313596.RB2501_06610	3.642e-233	732.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1HXT7@117743|Flavobacteriia	976|Bacteroidetes	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degQ	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS2_k127_1348328_5	1249997.JHZW01000002_gene1011	3.979e-64	220.0	COG0599@1|root,COG0639@1|root,COG0599@2|Bacteria,COG0639@2|Bacteria,4NFPU@976|Bacteroidetes,1IIYZ@117743|Flavobacteriia,2PHDX@252356|Maribacter	976|Bacteroidetes	T	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Metallophos_2
CMS2_k127_1348328_1	1250232.JQNJ01000001_gene1297	6.516e-183	576.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,1HXPJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
CMS2_k127_1348328_3	313596.RB2501_06625	2.64e-107	358.0	COG1309@1|root,COG1309@2|Bacteria,4NI80@976|Bacteroidetes,1HWTP@117743|Flavobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
CMS2_k127_1348328_2	143224.JQMD01000002_gene3187	9.606e-112	371.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1HYH4@117743|Flavobacteriia	976|Bacteroidetes	M	heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CMS2_k127_1348328_6	1121100.JCM6294_289	5.034e-36	138.0	COG0463@1|root,COG0463@2|Bacteria,4NGJK@976|Bacteroidetes,2FM49@200643|Bacteroidia,4AM20@815|Bacteroidaceae	976|Bacteroidetes	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254
CMS2_k127_1353344_1	1041826.FCOL_05720	5.743e-158	502.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia,2NUSI@237|Flavobacterium	976|Bacteroidetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
CMS2_k127_1353344_4	1223410.KN050846_gene2422	2.178e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,4NMSQ@976|Bacteroidetes,1I1P9@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_1353344_2	746697.Aeqsu_1756	1.153e-143	461.0	COG0596@1|root,COG0596@2|Bacteria,4NZUP@976|Bacteroidetes,1HZ6I@117743|Flavobacteriia	976|Bacteroidetes	S	Releases the N-terminal proline from various substrates	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS2_k127_1353344_0	204669.Acid345_1900	2.146e-182	593.0	COG2936@1|root,COG2936@2|Bacteria,3Y6W3@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS2_k127_1353344_3	1469557.JSWF01000032_gene3156	6.57e-76	262.0	2E3AK@1|root,30JD7@2|Bacteria,4NPG4@976|Bacteroidetes,1I2KJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1353344_5	329726.AM1_3715	1.074e-32	127.0	COG0376@1|root,COG0376@2|Bacteria,1G1NM@1117|Cyanobacteria	1117|Cyanobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS2_k127_13712_1	313596.RB2501_11297	1.871e-139	450.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS2_k127_13712_0	313596.RB2501_11292	6.795e-202	634.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS2_k127_1385994_0	313596.RB2501_14494	8.286e-247	764.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS2_k127_1385994_1	867900.Celly_2769	5.799e-41	153.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1HX2N@117743|Flavobacteriia,1F7Q8@104264|Cellulophaga	976|Bacteroidetes	M	COGs COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_1394580_0	313596.RB2501_10452	9.794e-291	895.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS2_k127_1394580_3	313596.RB2501_10462	1.711e-38	148.0	2DSID@1|root,32UT8@2|Bacteria,4NTWM@976|Bacteroidetes,1I4NX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1394580_1	313596.RB2501_10467	1.349e-167	531.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS2_k127_1394580_2	313596.RB2501_10472	1.688e-115	374.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS2_k127_1418520_3	313596.RB2501_16179	4.812e-47	171.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CMS2_k127_1418520_1	313596.RB2501_16174	2.681e-102	338.0	28JHY@1|root,2Z9BE@2|Bacteria,4NGKG@976|Bacteroidetes,1I1EX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1418520_2	313596.RB2501_16169	2.143e-56	205.0	2E6PN@1|root,331A0@2|Bacteria,4NUUD@976|Bacteroidetes,1I5A3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1418520_0	313596.RB2501_16164	1.104e-180	571.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1HX1G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS2_k127_1489789_1	313596.RB2501_03785	0.0	1444.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS2_k127_1489789_3	313596.RB2501_03780	9.249e-166	526.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia	976|Bacteroidetes	E	asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
CMS2_k127_1489789_4	313596.RB2501_03775	6.767e-89	304.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1I1FE@117743|Flavobacteriia	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
CMS2_k127_1489789_2	313596.RB2501_03770	1.778e-229	714.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HWPQ@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS2_k127_1489789_5	1121875.KB907550_gene892	5.543e-55	193.0	COG0526@1|root,COG0526@2|Bacteria,4PKJW@976|Bacteroidetes,1IJB9@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS2_k127_1489789_0	313596.RB2501_03760	0.0	1934.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IJBA@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CMS2_k127_1493928_1	313603.FB2170_17131	1.642e-131	424.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1HXB5@117743|Flavobacteriia,2PGXZ@252356|Maribacter	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
CMS2_k127_1493928_0	313596.RB2501_03105	1.85e-185	592.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS2_k127_1493928_2	313596.RB2501_03100	8.433e-101	336.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
CMS2_k127_1505515_3	1380600.AUYN01000009_gene1188	1.865e-94	313.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS2_k127_1505515_0	313596.RB2501_03185	0.0	1322.0	COG3203@1|root,COG3203@2|Bacteria,4PKBJ@976|Bacteroidetes,1HYG6@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_1505515_1	926559.JoomaDRAFT_1972	2.592e-190	599.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1HWQC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_1505515_2	313596.RB2501_03195	2.818e-134	430.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS2_k127_151699_2	313596.RB2501_11822	5.844e-178	560.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS2_k127_151699_1	313596.RB2501_11817	3.117e-235	735.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
CMS2_k127_151699_4	313596.RB2501_11812	5.786e-117	383.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,1HX2I@117743|Flavobacteriia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
CMS2_k127_151699_7	143224.JQMD01000002_gene4270	6.351e-19	92.0	2E6UP@1|root,331EC@2|Bacteria,4NUYV@976|Bacteroidetes,1I59A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_151699_3	313596.RB2501_11802	1.286e-157	507.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,1HYJ7@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
CMS2_k127_151699_0	313596.RB2501_11792	1.25e-294	909.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1HYHI@117743|Flavobacteriia	976|Bacteroidetes	J	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS2_k127_151699_5	313596.RB2501_11787	1.491e-46	168.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1I41M@117743|Flavobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS2_k127_151699_6	313596.RB2501_11782	1e-35	138.0	2E695@1|root,330X7@2|Bacteria,4NVE0@976|Bacteroidetes,1I53C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1534070_1	313596.RB2501_11537	3.735e-116	377.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1HXAF@117743|Flavobacteriia	976|Bacteroidetes	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS2_k127_1534070_3	1392498.JQLH01000001_gene1224	9.21e-32	124.0	2CTUX@1|root,32SU5@2|Bacteria,4NSSU@976|Bacteroidetes,1I51I@117743|Flavobacteriia,2PHNH@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1534070_2	313596.RB2501_11547	1.721e-81	274.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1I2I3@117743|Flavobacteriia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS2_k127_1534070_0	313596.RB2501_11552	3.951e-184	584.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1HXX6@117743|Flavobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT,PMT_2
CMS2_k127_1544819_5	313596.RB2501_02865	7.842e-17	80.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1HWQM@117743|Flavobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS2_k127_1544819_3	313596.RB2501_02860	1.981e-160	512.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS2_k127_1544819_2	313596.RB2501_02855	6.351e-224	700.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1HX68@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_1544819_4	313596.RB2501_02850	1.614e-105	346.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1I27S@117743|Flavobacteriia	976|Bacteroidetes	M	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
CMS2_k127_1544819_0	313596.RB2501_02845	2.66e-253	784.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS2_k127_1544819_1	313596.RB2501_02840	2.312e-236	737.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS2_k127_1549039_0	313596.RB2501_02395	1.837e-192	605.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_1549039_1	313596.RB2501_02390	5.571e-184	586.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
CMS2_k127_1576660_4	313596.RB2501_15699	3.284e-47	175.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1HXFC@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS2_k127_1576660_0	313596.RB2501_15704	6.154e-301	936.0	COG3920@1|root,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,TPR_12,TPR_8
CMS2_k127_1576660_1	1249997.JHZW01000003_gene2194	7.955e-134	429.0	COG3279@1|root,COG3279@2|Bacteria,4NF8A@976|Bacteroidetes,1HZ0Z@117743|Flavobacteriia,2PH7H@252356|Maribacter	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS2_k127_1576660_2	313596.RB2501_15719	1.629e-114	377.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,1HWR2@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_1576660_3	313596.RB2501_15724	1.615e-99	329.0	2CB9H@1|root,2Z8UH@2|Bacteria,4NHAQ@976|Bacteroidetes,1HYUV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_1577436_5	980584.AFPB01000015_gene580	1.322e-16	80.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1I19R@117743|Flavobacteriia,406H6@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	F	Formyl transferase	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS2_k127_1577436_3	313596.RB2501_07525	3.06e-96	321.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,1HXD6@117743|Flavobacteriia	976|Bacteroidetes	L	double-stranded RNA RNA-DNA hybrid binding protein	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
CMS2_k127_1577436_1	313596.RB2501_07520	8.134e-158	508.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1HY55@117743|Flavobacteriia	976|Bacteroidetes	G	sugar kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS2_k127_1577436_0	313596.RB2501_07515	0.0	1114.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS2_k127_1577436_2	1286632.P278_26710	7.501e-112	362.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS2_k127_1577436_4	313596.RB2501_07500	3.917e-25	107.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
CMS2_k127_1589156_4	1250232.JQNJ01000001_gene3887	3.793e-134	436.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia	976|Bacteroidetes	S	Sodium bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS2_k127_1589156_5	313596.RB2501_09080	2.89e-99	329.0	28HGK@1|root,2Z7SE@2|Bacteria,4NGDR@976|Bacteroidetes,1I856@117743|Flavobacteriia	976|Bacteroidetes	S	Malonate/sodium symporter MadM subunit	-	-	-	-	-	-	-	-	-	-	-	-	MadM
CMS2_k127_1589156_7	313596.RB2501_09085	1.211e-47	178.0	2CAQ0@1|root,32RRS@2|Bacteria,4NRRH@976|Bacteroidetes,1I9QS@117743|Flavobacteriia	976|Bacteroidetes	S	Malonate transporter MadL subunit	-	-	-	-	-	-	-	-	-	-	-	-	MadL
CMS2_k127_1589156_1	313596.RB2501_09090	2.815e-243	759.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1HZVU@117743|Flavobacteriia	976|Bacteroidetes	IQ	amp-binding	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
CMS2_k127_1589156_8	504472.Slin_0599	1.333e-31	141.0	COG2318@1|root,COG2318@2|Bacteria,4NNJ3@976|Bacteroidetes,47RJ8@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CMS2_k127_1589156_0	313596.RB2501_09095	1.559e-291	898.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1HXRM@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1589156_3	313596.RB2501_09100	1.223e-176	555.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,1HZVH@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS2_k127_1589156_11	1336243.JAEA01000001_gene1852	9.202e-12	73.0	COG4319@1|root,COG4319@2|Bacteria,1R2GQ@1224|Proteobacteria,2TZK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_1589156_2	1121875.KB907548_gene1620	9.741e-202	634.0	COG0520@1|root,COG0520@2|Bacteria,4NJCB@976|Bacteroidetes,1I0MB@117743|Flavobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_1589156_10	1223410.KN050846_gene2831	6.148e-24	111.0	2E3AK@1|root,30JD7@2|Bacteria,4NPG4@976|Bacteroidetes,1I2KR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1589156_6	1120965.AUBV01000005_gene1661	3.337e-67	234.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS2_k127_1593274_0	313603.FB2170_08664	0.0	1478.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PGZ8@252356|Maribacter	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_1593274_1	313596.RB2501_08995	0.0	1341.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
CMS2_k127_1593274_5	313596.RB2501_09000	4.651e-211	659.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS2_k127_1593274_3	313596.RB2501_09005	9.297e-285	876.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_1593274_8	313596.RB2501_09010	1.654e-111	362.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1593274_4	313596.RB2501_09015	9.299e-283	874.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
CMS2_k127_1593274_6	313596.RB2501_09020	1.056e-174	550.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility	gldN	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1593274_7	313596.RB2501_09025	2.165e-145	472.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1HWR8@117743|Flavobacteriia	976|Bacteroidetes	E	fad dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS2_k127_1593274_2	313596.RB2501_09030	0.0	1002.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWY2@117743|Flavobacteriia	976|Bacteroidetes	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_1593274_9	313596.RB2501_09035	5.88e-56	203.0	COG4886@1|root,COG4886@2|Bacteria,4NI2K@976|Bacteroidetes,1I0CI@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Leucine Rich Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_4,LRR_8
CMS2_k127_1608535_4	1046627.BZARG_1754	2.697e-06	53.0	COG2010@1|root,COG2010@2|Bacteria,4NIRV@976|Bacteroidetes,1HX5S@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF3365
CMS2_k127_1608535_2	1250232.JQNJ01000001_gene1599	4.057e-253	786.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia	976|Bacteroidetes	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS2_k127_1608535_0	313596.RB2501_07245	1.692e-266	824.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia	976|Bacteroidetes	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS2_k127_1608535_1	313596.RB2501_07240	3.389e-261	815.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,1HYC4@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS2_k127_1608535_3	1296416.JACB01000005_gene168	1.749e-105	345.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia,2YHQ0@290174|Aquimarina	976|Bacteroidetes	T	Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_1626926_0	385682.AFSL01000089_gene918	1.461e-216	687.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,2FN3P@200643|Bacteroidia,3XJHK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
CMS2_k127_1636031_2	313596.RB2501_15604	5.426e-08	58.0	COG1393@1|root,COG1393@2|Bacteria,4NSA6@976|Bacteroidetes,1I40J@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS2_k127_1636031_1	886377.Murru_2994	4.605e-185	582.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1HXZY@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS2_k127_1636031_0	313596.RB2501_15574	0.0	1063.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,1IJQ0@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CMS2_k127_1656727_0	313596.RB2501_04125	7.212e-243	752.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CMS2_k127_1656727_1	1004149.AFOE01000028_gene1774	7.587e-31	125.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1HX39@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS2_k127_1681882_0	1392498.JQLH01000001_gene1867	5.774e-164	520.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia,2PG8G@252356|Maribacter	976|Bacteroidetes	E	Aminotransferase class-V	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS2_k127_1681882_1	313596.RB2501_15334	1.097e-88	297.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
CMS2_k127_1699674_12	313596.RB2501_07480	2.246e-66	229.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,1HXRU@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_1699674_5	313596.RB2501_07470	4.209e-119	387.0	COG0589@1|root,COG0589@2|Bacteria,4NIWH@976|Bacteroidetes,1HXPX@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_1699674_13	313596.RB2501_07465	6.13e-66	229.0	COG0454@1|root,COG0456@2|Bacteria,4NPA8@976|Bacteroidetes,1I18M@117743|Flavobacteriia	976|Bacteroidetes	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_1699674_1	313596.RB2501_07460	1.367e-195	619.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS2_k127_1699674_7	313596.RB2501_07455	6.078e-114	372.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS2_k127_1699674_11	313596.RB2501_07445	2.276e-79	271.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,1I173@117743|Flavobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS2_k127_1699674_3	313596.RB2501_07440	2.296e-135	434.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia	976|Bacteroidetes	S	UDP-2,3-diacylglucosamine hydrolase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
CMS2_k127_1699674_0	313596.RB2501_07435	3.76e-267	833.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS2_k127_1699674_15	313596.RB2501_07430	2.086e-60	211.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,1I275@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS2_k127_1699674_9	1223410.KN050846_gene1735	8.172e-101	331.0	COG2128@1|root,COG2128@2|Bacteria,4NEJZ@976|Bacteroidetes,1HXPF@117743|Flavobacteriia	976|Bacteroidetes	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS2_k127_1699674_8	1250232.JQNJ01000001_gene1157	1.979e-102	338.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1HX5Y@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS2_k127_1699674_10	313596.RB2501_07410	3.967e-95	317.0	28KJI@1|root,2ZA4I@2|Bacteria,4NFR7@976|Bacteroidetes,1I30H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1699674_4	1250232.JQNJ01000001_gene1159	4.101e-121	390.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1HY1G@117743|Flavobacteriia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
CMS2_k127_1699674_2	313596.RB2501_07400	1.105e-161	516.0	COG0787@1|root,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1HWKS@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
CMS2_k127_1699674_14	313596.RB2501_07395	1.271e-64	223.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS2_k127_1699674_6	313596.RB2501_07390	4.168e-118	383.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_1705745_1	1392498.JQLH01000001_gene2940	3.932e-26	108.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia,2PGID@252356|Maribacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_1705745_2	1122179.KB890416_gene2646	3.61e-12	76.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
CMS2_k127_1705745_0	313596.RB2501_01021	4.06e-276	856.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_1710522_0	313596.RB2501_14989	2.07e-291	899.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	res	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
CMS2_k127_1710522_1	313596.RB2501_14984	8.296e-168	529.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,1HWQB@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS2_k127_173953_4	313596.RB2501_03715	1.88e-140	447.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
CMS2_k127_173953_1	313596.RB2501_03710	2.064e-308	947.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS2_k127_173953_5	313596.RB2501_03705	6.469e-101	329.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS2_k127_173953_6	313596.RB2501_03700	9.878e-89	295.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1HYBP@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_173953_2	313596.RB2501_03695	1.156e-250	777.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_173953_3	1348583.ATLH01000029_gene1334	1.504e-196	616.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia,1F8GP@104264|Cellulophaga	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, transmembrane domain	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CMS2_k127_173953_0	1250232.JQNJ01000001_gene2020	0.0	1083.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS2_k127_1748255_2	1122179.KB890433_gene4022	3.242e-144	464.0	COG2130@1|root,COG2130@2|Bacteria,4NGHX@976|Bacteroidetes,1IPTJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Zinc-binding dehydrogenase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N
CMS2_k127_1748255_4	313603.FB2170_14713	2.096e-119	390.0	COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,1IIGJ@117743|Flavobacteriia,2PIHR@252356|Maribacter	976|Bacteroidetes	IQ	KR domain	-	-	1.3.1.25	ko:K05783	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113	RC00271,RC01326,RC01327	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS2_k127_1748255_3	313596.RB2501_07225	9.832e-142	469.0	2C5U1@1|root,2Z80K@2|Bacteria,4NG4G@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1748255_0	1121875.KB907550_gene624	1.15e-153	497.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS2_k127_1748255_1	1178825.ALIH01000010_gene421	1.474e-149	486.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS2_k127_1748255_5	313596.RB2501_07230	5.193e-59	206.0	COG5349@1|root,COG5349@2|Bacteria,4NQ7W@976|Bacteroidetes,1I31N@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS2_k127_1801171_1	313596.RB2501_04120	5.062e-72	255.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1HX39@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS2_k127_1801171_0	313596.RB2501_04115	0.0	1043.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS2_k127_1808285_2	313596.RB2501_11637	2.094e-116	379.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_1808285_0	313596.RB2501_11652	9.885e-295	908.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1HYII@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_1808285_1	313596.RB2501_11657	2.011e-292	906.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HZDJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_1815174_5	313596.RB2501_11182	7.404e-113	372.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1HXRB@117743|Flavobacteriia	976|Bacteroidetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Lipocalin_2
CMS2_k127_1815174_6	1004149.AFOE01000009_gene2096	1.718e-64	228.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1I181@117743|Flavobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS2_k127_1815174_2	313596.RB2501_11192	1.967e-210	658.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1HXKY@117743|Flavobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS2_k127_1815174_4	1249997.JHZW01000001_gene3965	1.969e-127	415.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1HXY0@117743|Flavobacteriia,2PGA0@252356|Maribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS2_k127_1815174_1	313596.RB2501_11202	3.047e-218	684.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1HXQA@117743|Flavobacteriia	976|Bacteroidetes	CP	ABC transporter (Permease)	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS2_k127_1815174_3	313596.RB2501_11207	5.976e-130	421.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1HYUA@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS2_k127_1815174_0	313596.RB2501_11212	9.551e-226	703.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWRZ@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_1815174_7	313596.RB2501_11217	3.561e-39	149.0	28XYU@1|root,2ZJUQ@2|Bacteria,4NMNJ@976|Bacteroidetes,1I1SH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1830536_3	313596.RB2501_02220	1.082e-106	347.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_1830536_2	313596.RB2501_02225	4.335e-123	398.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1HYYA@117743|Flavobacteriia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS2_k127_1830536_5	313603.FB2170_16316	8.269e-31	122.0	2BZQB@1|root,32Y98@2|Bacteria,4NVDQ@976|Bacteroidetes,1I5G0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1830536_1	313596.RB2501_02230	2.06e-248	774.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1HYG1@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_1830536_0	313596.RB2501_02240	0.0	1405.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1HWZI@117743|Flavobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS2_k127_1830536_4	313596.RB2501_02245	1.593e-97	323.0	COG3663@1|root,COG3663@2|Bacteria,4NEZ4@976|Bacteroidetes,1HY0W@117743|Flavobacteriia	976|Bacteroidetes	L	G T U mismatch-specific DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1840232_0	313596.RB2501_03905	0.0	1399.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS2_k127_1840232_5	867900.Celly_1819	3.922e-45	169.0	29GBC@1|root,30398@2|Bacteria,4NNZ8@976|Bacteroidetes,1I26D@117743|Flavobacteriia,1F9E8@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1840232_6	313603.FB2170_03285	1.443e-15	85.0	2D460@1|root,32TGC@2|Bacteria,4NQMR@976|Bacteroidetes,1I4CI@117743|Flavobacteriia,2PHS0@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1840232_2	313596.RB2501_03910	8.68e-180	567.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS2_k127_1840232_1	313596.RB2501_03915	2.695e-210	657.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS2_k127_1840232_3	313596.RB2501_03920	1.302e-158	512.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1HWPY@117743|Flavobacteriia	976|Bacteroidetes	M	Transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS2_k127_1840232_4	313596.RB2501_03930	5.178e-78	262.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CMS2_k127_1841995_7	313596.RB2501_14524	9.177e-23	97.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1HXIE@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS2_k127_1841995_6	313596.RB2501_14529	7.544e-53	189.0	COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes,1I2WV@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS2_k127_1841995_3	313596.RB2501_14534	4.035e-286	897.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1HZ97@117743|Flavobacteriia	976|Bacteroidetes	E	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS2_k127_1841995_2	313596.RB2501_14544	0.0	1384.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS2_k127_1841995_1	313596.RB2501_14549	0.0	1554.0	COG0308@1|root,COG0308@2|Bacteria,4NEJR@976|Bacteroidetes,1HYMW@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS2_k127_1841995_4	1392498.JQLH01000001_gene1738	1.436e-123	398.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1HXT0@117743|Flavobacteriia,2PGE9@252356|Maribacter	976|Bacteroidetes	S	Possible lysine decarboxylase	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS2_k127_1841995_0	313596.RB2501_14559	0.0	1663.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS2_k127_1841995_5	313596.RB2501_14564	2.733e-86	287.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1I08A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1841995_8	1250006.JHZZ01000001_gene2144	2.42e-15	82.0	COG1573@1|root,COG1573@2|Bacteria,4NECP@976|Bacteroidetes,1HWXH@117743|Flavobacteriia,3VX2G@52959|Polaribacter	976|Bacteroidetes	L	Domain of unknown function (DUF4130	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
CMS2_k127_1864601_3	313596.RB2501_01625	3.928e-70	243.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS2_k127_1864601_2	313596.RB2501_01620	2.807e-87	292.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1I18T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1864601_1	313596.RB2501_01615	1.098e-138	453.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS2_k127_1864601_0	313596.RB2501_01610	4.375e-146	464.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia	976|Bacteroidetes	D	chromosome partitioning	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS2_k127_1864601_4	1178825.ALIH01000001_gene2696	4.586e-68	233.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS2_k127_1869295_2	313596.RB2501_07585	1.724e-113	368.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS2_k127_1869295_0	313596.RB2501_07580	0.0	1024.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HY6N@117743|Flavobacteriia	976|Bacteroidetes	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS2_k127_1869295_1	313596.RB2501_07575	4.963e-196	613.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1HWWV@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS2_k127_1869295_3	313596.RB2501_07565	3.287e-59	209.0	COG2954@1|root,COG2954@2|Bacteria,4NNGE@976|Bacteroidetes,1I1YE@117743|Flavobacteriia	976|Bacteroidetes	S	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
CMS2_k127_1869295_4	1178825.ALIH01000003_gene2161	2.378e-18	85.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS2_k127_1874509_5	616991.JPOO01000001_gene3836	2.356e-28	116.0	2BAFY@1|root,323WE@2|Bacteria,4NQ3E@976|Bacteroidetes,1I30F@117743|Flavobacteriia,23HCR@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1874509_1	313596.RB2501_12712	1.692e-163	521.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,1HYD6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1874509_4	313596.RB2501_12702	2.879e-54	199.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_1874509_3	313596.RB2501_12702	1.05e-92	310.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_1874509_0	313596.RB2501_12697	7.691e-230	717.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia	976|Bacteroidetes	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS2_k127_1874509_2	1004149.AFOE01000050_gene2654	5.635e-147	468.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1HZ8D@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS2_k127_1884414_4	1121890.AUDO01000005_gene1603	0.0005555	44.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,1I3ZA@117743|Flavobacteriia,2NWSI@237|Flavobacterium	976|Bacteroidetes	S	diacylglyceryl transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1884414_2	313596.RB2501_15354	4.715e-58	205.0	2AISX@1|root,3199U@2|Bacteria,4NQ7A@976|Bacteroidetes,1I3B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1884414_1	926559.JoomaDRAFT_2432	9.244e-59	208.0	28NQG@1|root,2ZBPZ@2|Bacteria,4NN1Z@976|Bacteroidetes,1I1W1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1884414_0	926559.JoomaDRAFT_2431	5.258e-86	293.0	COG1131@1|root,COG1131@2|Bacteria,4NIXI@976|Bacteroidetes,1HZ1P@117743|Flavobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_1884414_3	1286632.P278_16240	1.565e-56	213.0	COG1277@1|root,COG1277@2|Bacteria,4NICG@976|Bacteroidetes,1HZNH@117743|Flavobacteriia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
CMS2_k127_1885836_1	313596.RB2501_09110	4.809e-125	402.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,1HYKF@117743|Flavobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	AMPK1_CBM,CBM_48,Esterase
CMS2_k127_1885836_0	1121875.KB907547_gene3050	3.481e-187	599.0	COG0596@1|root,COG0596@2|Bacteria,4NQYB@976|Bacteroidetes,1I318@117743|Flavobacteriia	976|Bacteroidetes	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS2_k127_1885836_6	1189619.pgond44_14793	1.97e-22	108.0	2E3AK@1|root,32TSR@2|Bacteria,4NT8N@976|Bacteroidetes,1I449@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1885836_7	1223410.KN050846_gene2831	4.608e-21	104.0	2E3AK@1|root,30JD7@2|Bacteria,4NPG4@976|Bacteroidetes,1I2KR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1885836_8	1123037.AUDE01000014_gene350	8.496e-20	91.0	28WBK@1|root,2ZIC0@2|Bacteria,4P7B5@976|Bacteroidetes,1IBE5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1885836_5	1408473.JHXO01000009_gene3256	2.271e-46	171.0	COG4319@1|root,COG4319@2|Bacteria,4NSIN@976|Bacteroidetes	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_1885836_3	1007103.AFHW01000025_gene361	2.537e-96	339.0	COG1555@1|root,COG1555@2|Bacteria,1VTMY@1239|Firmicutes	1239|Firmicutes	L	COG1555 DNA uptake protein and related DNA-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CMS2_k127_1885836_2	313596.RB2501_14159	9.26e-110	362.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
CMS2_k127_1885836_4	1121007.AUML01000017_gene464	5.325e-65	226.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia,2YGKD@290174|Aquimarina	976|Bacteroidetes	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS2_k127_1944859_1	313596.RB2501_12442	0.0	1086.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
CMS2_k127_1944859_7	313596.RB2501_12447	5.066e-201	634.0	COG1470@1|root,COG1470@2|Bacteria,4NGFF@976|Bacteroidetes,1HZZG@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_1944859_8	313596.RB2501_12452	4.042e-196	619.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1HZEC@117743|Flavobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS2_k127_1944859_9	313596.RB2501_12457	1.106e-67	233.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes,1I3MJ@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
CMS2_k127_1944859_4	313596.RB2501_12462	2.579e-304	938.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,1HYJT@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_1944859_0	313596.RB2501_12467	0.0	1154.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia	976|Bacteroidetes	E	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_1944859_6	313596.RB2501_12472	4.507e-225	709.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
CMS2_k127_1944859_5	313596.RB2501_12477	3.224e-238	742.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS2_k127_1944859_12	1123507.ATVQ01000001_gene1773	3.897e-08	62.0	COG0259@1|root,COG0259@2|Bacteria,2H7ZA@201174|Actinobacteria,1WBXB@1268|Micrococcaceae	201174|Actinobacteria	H	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS2_k127_1944859_2	313596.RB2501_12502	8.351e-311	955.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS2_k127_1944859_3	313596.RB2501_12507	2.367e-305	950.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia	976|Bacteroidetes	EM	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
CMS2_k127_1944859_11	313596.RB2501_12512	1.846e-60	212.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1I2VB@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS2_k127_1944859_10	313596.RB2501_12517	1.089e-60	215.0	COG5661@1|root,COG5661@2|Bacteria,4NW11@976|Bacteroidetes,1I32R@117743|Flavobacteriia	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
CMS2_k127_198609_1	313596.RB2501_09620	8.371e-160	512.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_198609_0	313603.FB2170_17391	1.394e-172	542.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia,2PGP2@252356|Maribacter	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_2004372_2	616991.JPOO01000003_gene272	2.805e-30	122.0	2CMQC@1|root,32SFB@2|Bacteria,4NU5B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2004372_1	1249997.JHZW01000003_gene3407	2.901e-97	330.0	COG1376@1|root,COG1376@2|Bacteria,4NEE0@976|Bacteroidetes,1HXKU@117743|Flavobacteriia,2PI5M@252356|Maribacter	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
CMS2_k127_2004372_0	1121875.KB907547_gene3400	1.726e-170	542.0	COG3000@1|root,COG3000@2|Bacteria,4NISR@976|Bacteroidetes,1I0K6@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_2004372_3	1123234.AUKI01000011_gene1292	9.016e-05	44.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS2_k127_2007216_5	1250232.JQNJ01000001_gene3346	6.991e-40	154.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1HY79@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalase	treA	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase,Trehalase_Ca-bi
CMS2_k127_2007216_2	313596.RB2501_05230	2.502e-67	233.0	COG4319@1|root,COG4319@2|Bacteria,4NNSF@976|Bacteroidetes,1I234@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
CMS2_k127_2007216_7	313596.RB2501_05235	3.967e-26	113.0	2E2SQ@1|root,32XUY@2|Bacteria,4NTRQ@976|Bacteroidetes,1I42U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2007216_1	313596.RB2501_05240	5.148e-161	511.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS2_k127_2007216_0	313596.RB2501_05245	3.612e-250	777.0	COG0189@1|root,COG4067@1|root,COG0189@2|Bacteria,COG4067@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia	976|Bacteroidetes	HJ	Ribosomal protein S6 modification	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,Zn_protease
CMS2_k127_2007216_3	616991.JPOO01000001_gene2885	7.539e-45	168.0	COG3565@1|root,COG3565@2|Bacteria,4NRZG@976|Bacteroidetes,1I304@117743|Flavobacteriia	976|Bacteroidetes	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_2007216_4	313596.RB2501_05250	2.475e-43	160.0	2CJFR@1|root,32RQT@2|Bacteria,4NSHX@976|Bacteroidetes,1I4E2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2007216_6	313596.RB2501_05255	9.254e-36	135.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS2_k127_2014099_3	313596.RB2501_00861	1.368e-112	372.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1HYG0@117743|Flavobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
CMS2_k127_2014099_1	313596.RB2501_00856	1.728e-234	730.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,1HZF9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
CMS2_k127_2014099_0	313596.RB2501_00851	0.0	1073.0	COG3408@1|root,COG3408@2|Bacteria,4NHHR@976|Bacteroidetes,1I003@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C
CMS2_k127_2014099_2	313596.RB2501_00846	6.57e-143	460.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_2023235_2	313596.RB2501_09230	3.96e-38	143.0	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,1I1C4@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS2_k127_2023235_0	313596.RB2501_09225	1.849e-315	972.0	COG3186@1|root,COG3186@2|Bacteria,4NEX5@976|Bacteroidetes,1HX7H@117743|Flavobacteriia	976|Bacteroidetes	E	Pfam Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
CMS2_k127_2023235_1	1197477.IA57_02190	7.7e-89	302.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1HX8X@117743|Flavobacteriia	976|Bacteroidetes	E	Gscfa family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
CMS2_k127_2038314_10	313596.RB2501_08740	1.397e-156	500.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,1HWNT@117743|Flavobacteriia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
CMS2_k127_2038314_5	313596.RB2501_08735	1.071e-198	627.0	COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,1HY83@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
CMS2_k127_2038314_1	313596.RB2501_08730	3.834e-289	893.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,1HYWP@117743|Flavobacteriia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase domain protein	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
CMS2_k127_2038314_19	313596.RB2501_08725	1.48e-112	367.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,1HX0G@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_2038314_0	313596.RB2501_08720	3.953e-301	925.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
CMS2_k127_2038314_16	313596.RB2501_08715	6.509e-124	410.0	COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,1HY19@117743|Flavobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS2_k127_2038314_21	1189619.pgond44_09226	1.477e-20	99.0	COG1216@1|root,COG1216@2|Bacteria,4PKUG@976|Bacteroidetes,1IJFI@117743|Flavobacteriia,4C32S@83612|Psychroflexus	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS2_k127_2038314_18	313596.RB2501_08710	1.009e-114	371.0	COG0454@1|root,COG0454@2|Bacteria,4PKZU@976|Bacteroidetes,1IJKT@117743|Flavobacteriia	976|Bacteroidetes	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_2038314_4	313596.RB2501_08705	1.217e-216	677.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1HZAN@117743|Flavobacteriia	976|Bacteroidetes	E	argininosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS2_k127_2038314_9	313596.RB2501_08700	4.945e-161	512.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1HYTR@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_2038314_13	313596.RB2501_08695	7.054e-145	465.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1HX1Q@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS2_k127_2038314_6	313596.RB2501_08690	2.69e-194	611.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1HXQB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_2038314_11	313596.RB2501_08685	4.528e-156	498.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1HYDI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS2_k127_2038314_17	313596.RB2501_08680	4.676e-115	375.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1HYH7@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS2_k127_2038314_7	313596.RB2501_08675	2.013e-189	599.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1HY61@117743|Flavobacteriia	976|Bacteroidetes	E	Acetylornithine deacetylase	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_2038314_3	313596.RB2501_08670	2.981e-220	689.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1HX0C@117743|Flavobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
CMS2_k127_2038314_15	313596.RB2501_08660	3.417e-144	461.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1HXDH@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_2038314_14	313596.RB2501_08655	3.316e-144	465.0	COG0382@1|root,COG0382@2|Bacteria,4NGNA@976|Bacteroidetes,1HX57@117743|Flavobacteriia	976|Bacteroidetes	H	Prenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_2038314_8	313596.RB2501_08650	2.11e-168	532.0	COG1577@1|root,COG1577@2|Bacteria,4NDYJ@976|Bacteroidetes,1HX9R@117743|Flavobacteriia	976|Bacteroidetes	I	mevalonate kinase	mvaK	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS2_k127_2038314_12	313596.RB2501_08645	9.162e-149	479.0	COG3407@1|root,COG3407@2|Bacteria,4NDYX@976|Bacteroidetes,1HY6U@117743|Flavobacteriia	976|Bacteroidetes	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS2_k127_2038314_20	313596.RB2501_08640	2.629e-68	235.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,1I2B8@117743|Flavobacteriia	976|Bacteroidetes	T	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	tspO	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
CMS2_k127_2038314_2	313596.RB2501_08635	1.123e-231	723.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,1HX3Z@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS2_k127_2042705_0	313596.RB2501_15614	0.0	1051.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IJ8N@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
CMS2_k127_2042705_2	313596.RB2501_15619	3.136e-25	106.0	2E3TF@1|root,32YQY@2|Bacteria,4NUMK@976|Bacteroidetes,1I52K@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2042705_1	313596.RB2501_15624	7.484e-152	484.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1HX3F@117743|Flavobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS2_k127_2069356_0	313596.RB2501_14349	2.377e-230	723.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein related to penicillin acylase	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS2_k127_2077042_0	313596.RB2501_02705	0.0	1316.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CMS2_k127_2077042_4	313596.RB2501_02700	8.276e-89	298.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1HY9B@117743|Flavobacteriia	976|Bacteroidetes	J	rna methyltransferase	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS2_k127_2077042_2	313596.RB2501_02695	1.091e-120	391.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1HXZH@117743|Flavobacteriia	976|Bacteroidetes	S	porT protein	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_2077042_3	313596.RB2501_02690	1.731e-109	359.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1HX52@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS2_k127_2077042_1	313596.RB2501_02685	4.045e-249	773.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,1HWX3@117743|Flavobacteriia	976|Bacteroidetes	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS2_k127_2077042_5	313596.RB2501_02680	1.879e-79	267.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,1HXPV@117743|Flavobacteriia	976|Bacteroidetes	P	Trk-type K transport systems, membrane components	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS2_k127_2080968_2	313596.RB2501_09625	3.586e-141	449.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_2080968_0	313596.RB2501_09630	6.854e-210	661.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1HY15@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2080968_4	313596.RB2501_09635	1.881e-64	224.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia	976|Bacteroidetes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CMS2_k127_2080968_1	313596.RB2501_09640	3.324e-204	636.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS2_k127_2080968_3	888059.HMPREF9071_1268	1.481e-96	322.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia,1EQQ9@1016|Capnocytophaga	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_2082617_1	1121875.KB907553_gene123	9.729e-201	634.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
CMS2_k127_2082617_2	313596.RB2501_06330	7.396e-76	258.0	COG3637@1|root,COG3637@2|Bacteria,4NW7Z@976|Bacteroidetes,1I5D8@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS2_k127_2082617_0	313596.RB2501_06335	0.0	1082.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_2083361_4	313596.RB2501_13284	1.062e-22	100.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CMS2_k127_2083361_3	313596.RB2501_13279	5.008e-73	248.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2083361_1	313596.RB2501_13274	4.218e-146	465.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS2_k127_2083361_0	313596.RB2501_13269	1.282e-241	751.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1HX3N@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
CMS2_k127_2083361_2	313596.RB2501_13264	2.886e-134	432.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS2_k127_2087590_0	313596.RB2501_02810	4.627e-214	670.0	COG4099@1|root,COG4099@2|Bacteria,4PDKA@976|Bacteroidetes,1I0RG@117743|Flavobacteriia	976|Bacteroidetes	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
CMS2_k127_2087590_2	1348583.ATLH01000016_gene3441	1.964e-89	302.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,1HXMM@117743|Flavobacteriia,1F9YP@104264|Cellulophaga	976|Bacteroidetes	EG	EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
CMS2_k127_2087590_1	313596.RB2501_02815	2.465e-124	407.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_2087590_3	886377.Murru_2020	9.038e-57	206.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1I1X6@117743|Flavobacteriia	976|Bacteroidetes	S	YqeY-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS2_k127_2101471_0	1121875.KB907547_gene3464	6.469e-153	490.0	29MQ2@1|root,308MT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2101471_1	1121875.KB907547_gene3492	1.061e-130	430.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,1HZV3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
CMS2_k127_2101471_3	525257.HMPREF0204_10715	9e-54	200.0	2ACPQ@1|root,312AB@2|Bacteria,4PH6I@976|Bacteroidetes,1IH2F@117743|Flavobacteriia,3ZSVW@59732|Chryseobacterium	976|Bacteroidetes	S	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2268
CMS2_k127_2101471_2	1121875.KB907556_gene575	9.772e-69	243.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1HYE8@117743|Flavobacteriia	976|Bacteroidetes	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CMS2_k127_2101471_4	1121904.ARBP01000002_gene6773	2.614e-22	100.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47MN1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS2_k127_2111179_7	313596.RB2501_08040	2.836e-42	156.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1HX6M@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
CMS2_k127_2111179_3	313596.RB2501_08035	2.176e-148	484.0	COG0304@1|root,COG0304@2|Bacteria,4NGJD@976|Bacteroidetes,1HYKN@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS2_k127_2111179_1	313596.RB2501_08030	8.186e-186	589.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes,1HX8M@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
CMS2_k127_2111179_2	313596.RB2501_08025	7.894e-153	497.0	COG1807@1|root,COG1807@2|Bacteria,4NJ43@976|Bacteroidetes,1HX9S@117743|Flavobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS2_k127_2111179_5	1250232.JQNJ01000001_gene979	2.975e-74	258.0	COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,1HZ59@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS2_k127_2111179_6	313596.RB2501_08015	1.292e-47	177.0	2APBA@1|root,31EDH@2|Bacteria,4NPIT@976|Bacteroidetes,1I25X@117743|Flavobacteriia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS2_k127_2111179_4	313596.RB2501_08010	4.341e-117	388.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,1HY28@117743|Flavobacteriia	976|Bacteroidetes	H	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_2111179_9	143224.JQMD01000002_gene2826	7.354e-37	147.0	COG1247@1|root,COG1247@2|Bacteria,4NP40@976|Bacteroidetes,1I20J@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_2111179_8	313596.RB2501_08005	1.121e-39	149.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1I5R2@117743|Flavobacteriia	976|Bacteroidetes	C	COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit)	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CMS2_k127_2111179_0	313596.RB2501_08000	1.296e-306	942.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS2_k127_2133615_2	143224.JQMD01000002_gene1942	2.358e-133	434.0	COG1524@1|root,COG1524@2|Bacteria,4NGHN@976|Bacteroidetes,1HZPJ@117743|Flavobacteriia	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS2_k127_2133615_0	313596.RB2501_12834	1.921e-169	549.0	COG1082@1|root,COG1082@2|Bacteria,4NHXX@976|Bacteroidetes,1HZSN@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2133615_1	313596.RB2501_12829	2.656e-169	539.0	COG0337@1|root,COG0337@2|Bacteria,4NHE3@976|Bacteroidetes,1I0VF@117743|Flavobacteriia	976|Bacteroidetes	E	3-dehydroquinate synthase	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS2_k127_2138421_4	313596.RB2501_06465	5.043e-80	270.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_2138421_1	313596.RB2501_06470	7.853e-115	387.0	COG3266@1|root,COG3266@2|Bacteria,4NH1U@976|Bacteroidetes,1HX0D@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_2138421_3	313596.RB2501_06475	8.189e-112	366.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia	976|Bacteroidetes	I	acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_2138421_0	313596.RB2501_06480	2.108e-182	575.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS2_k127_2138421_2	313596.RB2501_06485	2.129e-113	376.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1HXG0@117743|Flavobacteriia	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
CMS2_k127_2138421_5	313596.RB2501_06495	6.967e-54	193.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_213858_0	313596.RB2501_03355	2.723e-289	906.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1HXHN@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
CMS2_k127_213858_1	313596.RB2501_03345	1.385e-146	467.0	2BVTQ@1|root,2Z7J9@2|Bacteria,4NGSY@976|Bacteroidetes,1HWRX@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
CMS2_k127_213858_2	313603.FB2170_02795	1.877e-23	99.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1IJBB@117743|Flavobacteriia,2PGG0@252356|Maribacter	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS2_k127_2147868_1	1461693.ATO10_09273	1.551e-77	276.0	COG0682@1|root,COG0682@2|Bacteria,1R7B3@1224|Proteobacteria	1224|Proteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT,PAP2_3,PEMT
CMS2_k127_2147868_0	1121875.KB907547_gene2897	3.423e-81	280.0	COG5504@1|root,COG5504@2|Bacteria,4NJ10@976|Bacteroidetes,1HZGD@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF2268
CMS2_k127_2147868_2	1353276.JADR01000009_gene1788	5.159e-05	46.0	2E3AK@1|root,32R5K@2|Bacteria,4PQ29@976|Bacteroidetes,1IKYS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2149755_16	1348583.ATLH01000031_gene2154	3.658e-77	260.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,1F8Z4@104264|Cellulophaga	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS2_k127_2149755_4	313596.RB2501_07980	5.599e-247	775.0	28IHD@1|root,2Z8IK@2|Bacteria,4NF9V@976|Bacteroidetes,1HY20@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
CMS2_k127_2149755_9	1392498.JQLH01000001_gene3729	7.044e-151	480.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1HXJZ@117743|Flavobacteriia,2PG6Y@252356|Maribacter	976|Bacteroidetes	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
CMS2_k127_2149755_13	313596.RB2501_07970	1.895e-116	381.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1HXD5@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS2_k127_2149755_18	313596.RB2501_07965	1.157e-59	207.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,1I1ZA@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS2_k127_2149755_8	313596.RB2501_07960	1.679e-168	537.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1HXYD@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS2_k127_2149755_6	313596.RB2501_07955	2.035e-193	608.0	COG2382@1|root,COG2382@2|Bacteria,4PKIX@976|Bacteroidetes,1IJAG@117743|Flavobacteriia	976|Bacteroidetes	P	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
CMS2_k127_2149755_3	313596.RB2501_07950	4.01e-247	768.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1HY3T@117743|Flavobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS2_k127_2149755_7	313596.RB2501_07945	3.236e-180	568.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1HY7T@117743|Flavobacteriia	976|Bacteroidetes	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_2149755_10	313596.RB2501_07940	6.526e-149	479.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1HY7R@117743|Flavobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS2_k127_2149755_0	313596.RB2501_07930	9.76e-300	935.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1HY4T@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_2149755_1	313596.RB2501_07925	2.113e-298	919.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS2_k127_2149755_11	313596.RB2501_07920	1.323e-136	443.0	2DPRW@1|root,3334N@2|Bacteria,4NJ3S@976|Bacteroidetes,1HZ3B@117743|Flavobacteriia	976|Bacteroidetes	J	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2149755_17	1121012.AUKX01000002_gene3389	6.052e-74	255.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1I22C@117743|Flavobacteriia,23FWY@178469|Arenibacter	976|Bacteroidetes	S	Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
CMS2_k127_2149755_5	313596.RB2501_07910	2.38e-243	762.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
CMS2_k127_2149755_15	886377.Murru_1098	1.353e-95	319.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia	976|Bacteroidetes	S	amidohydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS2_k127_2149755_19	313596.RB2501_07900	1.295e-52	191.0	COG0666@1|root,COG0666@2|Bacteria,4NSX8@976|Bacteroidetes,1I2UW@117743|Flavobacteriia	976|Bacteroidetes	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
CMS2_k127_2149755_14	688270.Celal_1184	1.139e-114	387.0	COG4085@1|root,COG4085@2|Bacteria,4NIB0@976|Bacteroidetes,1HWVQ@117743|Flavobacteriia,1F8AG@104264|Cellulophaga	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,LTD
CMS2_k127_2149755_2	313596.RB2501_07890	9.078e-251	802.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1HYS9@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug
CMS2_k127_2149755_12	313596.RB2501_07885	9.833e-121	394.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HX79@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_21583_1	143224.JQMD01000002_gene882	1.381e-94	312.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1HYQE@117743|Flavobacteriia	976|Bacteroidetes	G	L-sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS2_k127_21583_0	1121875.KB907548_gene1529	0.0	1158.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1I0HE@117743|Flavobacteriia	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_21583_2	313596.RB2501_14804	2.592e-47	172.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1I911@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_2176480_2	1004149.AFOE01000006_gene2038	1.068e-105	346.0	COG1064@1|root,COG1064@2|Bacteria,4NTXE@976|Bacteroidetes,1IJWX@117743|Flavobacteriia	976|Bacteroidetes	S	Alanine dehydrogenase/PNT, C-terminal domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS2_k127_2176480_0	313603.FB2170_15613	2.487e-138	445.0	COG1597@1|root,COG1597@2|Bacteria,4NGPY@976|Bacteroidetes,1IIYP@117743|Flavobacteriia	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS2_k127_2176480_1	391587.KAOT1_09251	1.178e-120	397.0	COG4242@1|root,COG4242@2|Bacteria,4NIBM@976|Bacteroidetes,1HWYN@117743|Flavobacteriia	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
CMS2_k127_2176480_3	1120965.AUBV01000006_gene2226	4.079e-90	304.0	COG3703@1|root,COG3703@2|Bacteria,4NRNA@976|Bacteroidetes	976|Bacteroidetes	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS2_k127_2176480_4	639030.JHVA01000001_gene2264	8.918e-09	61.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	fosB2	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS2_k127_2183778_2	313596.RB2501_07725	3.742e-172	543.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS2_k127_2183778_0	313596.RB2501_07720	5.574e-264	822.0	COG0578@1|root,COG0578@2|Bacteria,4PKIZ@976|Bacteroidetes	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS2_k127_2183778_7	313596.RB2501_07715	7.31e-41	153.0	COG2329@1|root,COG2329@2|Bacteria,4NS8X@976|Bacteroidetes,1I3WG@117743|Flavobacteriia	976|Bacteroidetes	S	involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS2_k127_2183778_5	655815.ZPR_0326	1.7e-57	202.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2183778_4	313603.FB2170_06855	1.422e-63	222.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia,2PHF9@252356|Maribacter	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS2_k127_2183778_6	313596.RB2501_07700	9.273e-49	180.0	COG2340@1|root,COG2340@2|Bacteria,4NNKS@976|Bacteroidetes,1I1XU@117743|Flavobacteriia	976|Bacteroidetes	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS2_k127_2183778_3	1121875.KB907547_gene3299	2.415e-92	308.0	COG1917@1|root,COG1917@2|Bacteria,4PKJ0@976|Bacteroidetes,1IJAI@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
CMS2_k127_2183778_1	313596.RB2501_07690	3.967e-246	765.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_218753_1	313596.RB2501_01885	6.045e-103	337.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1HY9T@117743|Flavobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS2_k127_218753_0	313596.RB2501_01880	1.524e-203	642.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia	976|Bacteroidetes	C	dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_218753_2	313596.RB2501_01875	3.766e-94	311.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS2_k127_2209256_3	313596.RB2501_05280	6.353e-70	239.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
CMS2_k127_2209256_4	1004149.AFOE01000033_gene692	2.103e-64	222.0	COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
CMS2_k127_2209256_2	313596.RB2501_05270	3.462e-97	324.0	28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,1HZ05@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2209256_0	313596.RB2501_05265	2.016e-275	851.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1HXKA@117743|Flavobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS2_k127_2209256_1	1121007.AUML01000003_gene2619	7.114e-100	327.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia,2YH3E@290174|Aquimarina	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS2_k127_2209612_0	313596.RB2501_02650	1.608e-303	934.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1HYV0@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
CMS2_k127_2209612_4	313596.RB2501_02665	6.473e-98	325.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1HYFU@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS2_k127_2209612_1	313596.RB2501_02670	5.485e-213	668.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS2_k127_2209612_2	313596.RB2501_02675	2.911e-211	665.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_2209612_3	313596.RB2501_02680	3.074e-203	634.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,1HXPV@117743|Flavobacteriia	976|Bacteroidetes	P	Trk-type K transport systems, membrane components	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS2_k127_2212900_5	1178825.ALIH01000006_gene1534	4.858e-86	292.0	COG0730@1|root,COG0730@2|Bacteria,4NFTT@976|Bacteroidetes,1HWXF@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_2212900_2	313596.RB2501_11867	2.22e-135	436.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia	976|Bacteroidetes	O	molecular chaperone	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS2_k127_2212900_3	313596.RB2501_11877	7.596e-116	376.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,1HZKS@117743|Flavobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS2_k127_2212900_0	313596.RB2501_11882	7.303e-210	659.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1HXJE@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS2_k127_2212900_1	313596.RB2501_11887	1.56e-142	460.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1HZI0@117743|Flavobacteriia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
CMS2_k127_2212900_6	1121875.KB907549_gene2104	4.047e-41	156.0	COG3059@1|root,COG3059@2|Bacteria,4NNX8@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
CMS2_k127_2212900_7	313596.RB2501_11892	1.062e-40	152.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1I3YR@117743|Flavobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS2_k127_2212900_4	313596.RB2501_11897	2.835e-111	367.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_2212900_9	313596.RB2501_11902	2.533e-05	48.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,1HYJ8@117743|Flavobacteriia	976|Bacteroidetes	K	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
CMS2_k127_2232386_8	313596.RB2501_13189	3.396e-34	132.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1HYZ1@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
CMS2_k127_2232386_6	1120966.AUBU01000001_gene775	9.423e-101	337.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,47JUA@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CMS2_k127_2232386_0	313596.RB2501_13194	4.551e-256	794.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,1HYAT@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
CMS2_k127_2232386_3	313596.RB2501_13199	2.984e-134	438.0	COG2265@1|root,COG2265@2|Bacteria,4PKBS@976|Bacteroidetes,1HXP3@117743|Flavobacteriia	976|Bacteroidetes	J	(SAM)-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95,Methyltransf_15
CMS2_k127_2232386_1	313596.RB2501_13204	2.19e-153	492.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,1HYDA@117743|Flavobacteriia	976|Bacteroidetes	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS2_k127_2232386_4	313596.RB2501_13209	3.158e-111	363.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1HXQK@117743|Flavobacteriia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CMS2_k127_2232386_5	313596.RB2501_13214	5.783e-105	349.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1HY0K@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS2_k127_2232386_7	313596.RB2501_13219	8.38e-42	156.0	COG3070@1|root,COG3070@2|Bacteria,4NTQF@976|Bacteroidetes,1II85@117743|Flavobacteriia	976|Bacteroidetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS2_k127_2232386_2	313596.RB2501_13224	4.776e-148	471.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS2_k127_223423_2	313596.RB2501_15334	1.864e-30	125.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
CMS2_k127_223423_1	886377.Murru_3071	1.476e-67	231.0	COG1145@1|root,COG1145@2|Bacteria,4NNF9@976|Bacteroidetes,1I1ZJ@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
CMS2_k127_223423_0	313596.RB2501_15324	1.273e-141	456.0	COG0417@1|root,COG0417@2|Bacteria,4NGEJ@976|Bacteroidetes,1HXZC@117743|Flavobacteriia	976|Bacteroidetes	L	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_2248695_1	313603.FB2170_09206	2.058e-262	816.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CMS2_k127_2248695_2	1121875.KB907546_gene2494	6.033e-209	656.0	COG3250@1|root,COG3250@2|Bacteria,4NHRV@976|Bacteroidetes,1IKPT@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
CMS2_k127_2248695_0	1347342.BN863_18730	0.0	1097.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes,1HYBU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2251170_3	313596.RB2501_03290	2.36e-95	316.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1HX38@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS2_k127_2251170_2	313596.RB2501_03285	2.867e-97	322.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia	976|Bacteroidetes	S	Acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS2_k127_2251170_0	313596.RB2501_03280	1.012e-138	445.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1HY0R@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS2_k127_2251170_1	313596.RB2501_03275	1.038e-131	423.0	COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,1I060@117743|Flavobacteriia	976|Bacteroidetes	M	Inorganic polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS2_k127_2251170_4	313596.RB2501_03270	6.677e-75	256.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS2_k127_2319593_1	1121875.KB907550_gene641	6.218e-172	544.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1HZ1W@117743|Flavobacteriia	976|Bacteroidetes	T	Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
CMS2_k127_2319593_3	1121875.KB907551_gene965	1.167e-40	160.0	28KEX@1|root,2ZA14@2|Bacteria,4PAQ1@976|Bacteroidetes,1I8NT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2319593_2	313596.RB2501_10567	6.138e-52	191.0	2AVDM@1|root,31M58@2|Bacteria,4NUN6@976|Bacteroidetes,1I278@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
CMS2_k127_2319593_0	313596.RB2501_10562	1.114e-254	796.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1HX0N@117743|Flavobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS2_k127_2324169_11	313596.RB2501_11552	2.258e-39	150.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1HXX6@117743|Flavobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT,PMT_2
CMS2_k127_2324169_9	688270.Celal_2643	2.885e-83	285.0	COG0392@1|root,COG0392@2|Bacteria,4NMZ1@976|Bacteroidetes,1I0GR@117743|Flavobacteriia,1F9SP@104264|Cellulophaga	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS2_k127_2324169_1	313596.RB2501_11562	5.563e-180	568.0	COG0463@1|root,COG0463@2|Bacteria,4PMAN@976|Bacteroidetes,1IJPP@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_2324169_3	313596.RB2501_11567	1.428e-135	439.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1HWNS@117743|Flavobacteriia	976|Bacteroidetes	E	periplasmic protein kinase ArgK and related	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS2_k127_2324169_7	313596.RB2501_11572	5.453e-86	287.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,1I1SZ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CMS2_k127_2324169_8	313596.RB2501_11582	1.603e-84	284.0	COG1595@1|root,COG1595@2|Bacteria,4NN0Y@976|Bacteroidetes,1I0F7@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_2324169_15	926559.JoomaDRAFT_0316	1.337e-05	54.0	2BAFY@1|root,323WE@2|Bacteria,4NQ3E@976|Bacteroidetes,1I30F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2324169_2	313596.RB2501_11592	2.063e-164	530.0	28IKH@1|root,2Z8M8@2|Bacteria,4NFVI@976|Bacteroidetes,1HWNR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2324169_5	313596.RB2501_11597	2.548e-94	314.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HXRV@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS2_k127_2324169_10	313596.RB2501_11602	5.007e-59	211.0	COG0739@1|root,COG0739@2|Bacteria,4NN4Q@976|Bacteroidetes,1I1CW@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_2324169_6	313596.RB2501_11617	6.126e-90	303.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1HYXD@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS2_k127_2324169_4	313596.RB2501_11622	1.189e-120	390.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1HY18@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_2324169_0	313596.RB2501_11627	0.0	1303.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1HZCQ@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_2324169_12	313596.RB2501_11632	3.616e-22	97.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1I15K@117743|Flavobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
CMS2_k127_2342167_1	313596.RB2501_11902	5.275e-107	351.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,1HYJ8@117743|Flavobacteriia	976|Bacteroidetes	K	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
CMS2_k127_2342167_0	313596.RB2501_11907	1.837e-191	606.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1HWM0@117743|Flavobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
CMS2_k127_2344262_7	313603.FB2170_10946	1.407e-48	177.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1HWQ2@117743|Flavobacteriia,2PFZU@252356|Maribacter	976|Bacteroidetes	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_2344262_6	313596.RB2501_15139	1.539e-86	294.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1HXYC@117743|Flavobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS2_k127_2344262_0	313596.RB2501_15144	5.373e-196	616.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
CMS2_k127_2344262_5	313596.RB2501_15149	5.523e-128	417.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1HYNA@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_2344262_1	313596.RB2501_15154	1.732e-176	562.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS2_k127_2344262_2	313596.RB2501_15159	1.005e-150	479.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS2_k127_2344262_3	313596.RB2501_15164	2.443e-148	473.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1HXP9@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS2_k127_2344262_4	313596.RB2501_15169	5.694e-139	452.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2351561_9	746697.Aeqsu_1582	1.861e-09	58.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1I3YF@117743|Flavobacteriia	976|Bacteroidetes	O	Nitrogen fixation protein NifU	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
CMS2_k127_2351561_0	1121875.KB907547_gene3157	5.918e-197	618.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1HWR0@117743|Flavobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS2_k127_2351561_6	313596.RB2501_08425	5.197e-57	199.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1I2Y7@117743|Flavobacteriia	976|Bacteroidetes	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CMS2_k127_2351561_5	313596.RB2501_08420	4.976e-100	329.0	COG1280@1|root,COG1280@2|Bacteria,4NRV8@976|Bacteroidetes,1HY8C@117743|Flavobacteriia	976|Bacteroidetes	E	Pfam LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS2_k127_2351561_3	313596.RB2501_08415	3.125e-116	377.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1HXZG@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS2_k127_2351561_1	313596.RB2501_08410	6.753e-171	542.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1HXVZ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS2_k127_2351561_2	313596.RB2501_08405	3.613e-128	411.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_2351561_7	313596.RB2501_08400	9.568e-40	151.0	2E8RM@1|root,3332M@2|Bacteria,4NUWG@976|Bacteroidetes,1I59N@117743|Flavobacteriia	976|Bacteroidetes	S	secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2351561_8	313596.RB2501_08395	2.946e-33	131.0	COG2374@1|root,COG2374@2|Bacteria,4NKW3@976|Bacteroidetes,1IJPF@117743|Flavobacteriia	976|Bacteroidetes	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CMS2_k127_2351561_4	313596.RB2501_08390	2.98e-104	346.0	COG1541@1|root,COG1541@2|Bacteria,4PKAN@976|Bacteroidetes,1HX4F@117743|Flavobacteriia	976|Bacteroidetes	H	PFAM Acyl-protein synthetase, LuxE	luxE	-	-	-	-	-	-	-	-	-	-	-	LuxE
CMS2_k127_2380428_2	313596.RB2501_15264	1.993e-140	452.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS2_k127_2380428_1	313596.RB2501_15259	1.43e-195	617.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1HWSR@117743|Flavobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
CMS2_k127_2380428_3	313596.RB2501_15254	7.693e-47	171.0	2CT98@1|root,32SSW@2|Bacteria,4NSGA@976|Bacteroidetes,1I40N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
CMS2_k127_2380428_0	313596.RB2501_15249	8.689e-232	720.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS2_k127_2421067_7	313596.RB2501_02495	4.136e-55	199.0	COG0454@1|root,COG0456@2|Bacteria,4NQ82@976|Bacteroidetes,1I2X6@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_2421067_1	313596.RB2501_02500	4.481e-97	321.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1HYQJ@117743|Flavobacteriia	976|Bacteroidetes	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
CMS2_k127_2421067_4	1121012.AUKX01000014_gene2707	2.247e-65	228.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1I2HK@117743|Flavobacteriia,23H0Y@178469|Arenibacter	976|Bacteroidetes	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS2_k127_2421067_9	313596.RB2501_02510	4.637e-38	145.0	COG1826@1|root,COG1826@2|Bacteria,4NSAK@976|Bacteroidetes,1I40K@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS2_k127_2421067_0	313596.RB2501_02515	0.0	1382.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS2_k127_2421067_5	313596.RB2501_02520	2.407e-59	209.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1I2EY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2421067_2	313596.RB2501_02525	1.102e-91	308.0	28Z2A@1|root,2ZKUT@2|Bacteria,4NSQ0@976|Bacteroidetes,1I0GS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_2421067_3	313596.RB2501_02530	7.799e-89	300.0	28IMZ@1|root,2Z8NF@2|Bacteria,4NIZ8@976|Bacteroidetes,1I0D0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_2421067_8	313596.RB2501_02535	1.07e-49	200.0	COG1511@1|root,COG3210@1|root,COG5295@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,4NJQ0@976|Bacteroidetes,1I01W@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2421067_6	1249997.JHZW01000003_gene3624	3.31e-59	229.0	COG0406@1|root,COG1511@1|root,COG3210@1|root,COG5644@1|root,COG0406@2|Bacteria,COG1511@2|Bacteria,COG3210@2|Bacteria,COG5644@2|Bacteria,4PKI0@976|Bacteroidetes,1HYWF@117743|Flavobacteriia,2PIGN@252356|Maribacter	976|Bacteroidetes	U	PFAM Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
CMS2_k127_2439991_4	313596.RB2501_02915	5.222e-13	69.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS2_k127_2439991_3	313596.RB2501_02920	2.027e-26	116.0	2E3G3@1|root,32YEY@2|Bacteria,4NSGS@976|Bacteroidetes,1I4CR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2439991_1	313596.RB2501_02925	2.056e-101	334.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS2_k127_2439991_0	313596.RB2501_02930	1.333e-105	348.0	COG0589@1|root,COG0589@2|Bacteria,4NQA1@976|Bacteroidetes,1I2WM@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_2439991_2	313596.RB2501_02935	1.024e-69	239.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1HY3E@117743|Flavobacteriia	976|Bacteroidetes	G	phosphorylase	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
CMS2_k127_2467654_1	313596.RB2501_07840	5.727e-226	702.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
CMS2_k127_2467654_0	313596.RB2501_07835	0.0	1182.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
CMS2_k127_2467654_2	313596.RB2501_07830	6.561e-32	125.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS2_k127_2500562_1	886377.Murru_0392	6.139e-156	499.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1HY1B@117743|Flavobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CMS2_k127_2500562_0	313596.RB2501_11132	1.327e-237	737.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1HYDV@117743|Flavobacteriia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS2_k127_2534820_1	1249997.JHZW01000002_gene699	2.789e-76	261.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1HXQ5@117743|Flavobacteriia,2PGM7@252356|Maribacter	976|Bacteroidetes	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS2_k127_2534820_0	313596.RB2501_04980	0.0	1280.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
CMS2_k127_2535952_3	1250232.JQNJ01000001_gene780	2.494e-24	103.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS2_k127_2535952_2	313596.RB2501_00806	1.252e-35	142.0	COG0845@1|root,COG0845@2|Bacteria,4NSWM@976|Bacteroidetes,1I1UM@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
CMS2_k127_2535952_1	313596.RB2501_00811	2.093e-158	509.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,1HXSD@117743|Flavobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_2535952_0	313596.RB2501_00816	0.0	1955.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
CMS2_k127_2535952_4	313596.RB2501_00821	3.072e-18	87.0	2DBJ2@1|root,32TXJ@2|Bacteria,4NTRP@976|Bacteroidetes,1I43A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2591157_10	313596.RB2501_01650	4.57e-75	254.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_2591157_5	313596.RB2501_01655	1.155e-134	432.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1HX94@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
CMS2_k127_2591157_0	313596.RB2501_01660	2.795e-279	869.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1HWX8@117743|Flavobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS2_k127_2591157_12	313596.RB2501_01665	3.52e-43	160.0	2D57J@1|root,32TIE@2|Bacteria,4NSGD@976|Bacteroidetes,1I46S@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2591157_8	313596.RB2501_01670	6.447e-77	260.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,1I18R@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS2_k127_2591157_6	313596.RB2501_01675	2.325e-118	385.0	COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,1IJP8@117743|Flavobacteriia	976|Bacteroidetes	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
CMS2_k127_2591157_2	313596.RB2501_01685	1.863e-189	595.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1HX8P@117743|Flavobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
CMS2_k127_2591157_14	313596.RB2501_01690	8.983e-26	113.0	2CC77@1|root,32S0M@2|Bacteria,4NS9F@976|Bacteroidetes,1I3Y8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
CMS2_k127_2591157_13	313596.RB2501_01695	9.483e-36	138.0	COG5512@1|root,COG5512@2|Bacteria,4NSDR@976|Bacteroidetes,1I46E@117743|Flavobacteriia	976|Bacteroidetes	S	Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS2_k127_2591157_9	313603.FB2170_09546	2.126e-76	262.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1I1AD@117743|Flavobacteriia,2PHDN@252356|Maribacter	976|Bacteroidetes	F	NDK	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS2_k127_2591157_4	313596.RB2501_01710	5.579e-141	455.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia	976|Bacteroidetes	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS2_k127_2591157_11	313596.RB2501_01715	5.611e-75	256.0	COG0545@1|root,COG0545@2|Bacteria,4NN5Q@976|Bacteroidetes,1I2A2@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	gldI	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
CMS2_k127_2591157_3	313596.RB2501_01720	4.186e-165	527.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
CMS2_k127_2591157_1	313596.RB2501_01725	4.487e-198	631.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,1HWUA@117743|Flavobacteriia	976|Bacteroidetes	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_2591157_7	313596.RB2501_01730	2.932e-118	387.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1HX8A@117743|Flavobacteriia	976|Bacteroidetes	S	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
CMS2_k127_2617541_4	1121875.KB907548_gene1623	3.509e-18	87.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CMS2_k127_2617541_2	1121875.KB907550_gene717	2.131e-131	445.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
CMS2_k127_2617541_3	313596.RB2501_09335	4.923e-121	396.0	28KH6@1|root,2ZA2R@2|Bacteria,4NI7X@976|Bacteroidetes,1HYH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2617541_1	313596.RB2501_09355	2.151e-277	857.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1HWNF@117743|Flavobacteriia	976|Bacteroidetes	E	NADPH-dependent glutamate synthase beta chain and related	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS2_k127_2617541_0	313596.RB2501_09360	0.0	1256.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS2_k127_2622475_1	1189619.pgond44_05365	5.453e-270	839.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia,4C43R@83612|Psychroflexus	976|Bacteroidetes	F	Formate--tetrahydrofolate ligase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS2_k127_2622475_0	1122176.KB903537_gene1670	0.0	1033.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1IWR2@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
CMS2_k127_2632687_2	313596.RB2501_12552	3.153e-102	334.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1HWQ1@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS2_k127_2632687_1	313596.RB2501_12557	1.022e-161	513.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS2_k127_2632687_0	313596.RB2501_12562	1.578e-263	823.0	COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1HZMD@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS2_k127_2632687_3	313596.RB2501_12567	2.491e-08	55.0	COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,1HZA9@117743|Flavobacteriia	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS2_k127_2639514_1	760192.Halhy_2061	3.028e-84	289.0	COG0665@1|root,COG0665@2|Bacteria,4NKQK@976|Bacteroidetes,1IWYI@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS2_k127_2639514_0	760192.Halhy_5255	1.204e-144	469.0	COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,1IR7C@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
CMS2_k127_2639514_2	1233950.IW22_23485	3.889e-47	179.0	2C312@1|root,2Z7N1@2|Bacteria,4NFNW@976|Bacteroidetes,1I541@117743|Flavobacteriia,3ZRGY@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2639514_3	1242864.D187_007077	1.072e-35	142.0	2E3VP@1|root,32YSV@2|Bacteria,1RFZF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2662075_8	313596.RB2501_04115	1.891e-27	114.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS2_k127_2662075_1	313596.RB2501_04110	1.893e-182	580.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS2_k127_2662075_0	313596.RB2501_04105	1.112e-268	835.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CMS2_k127_2662075_3	313596.RB2501_04100	5.52e-131	423.0	COG0583@1|root,COG0583@2|Bacteria,4NGAB@976|Bacteroidetes,1HZVD@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS2_k127_2662075_5	313596.RB2501_04095	1.188e-88	295.0	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,1I1BE@117743|Flavobacteriia	976|Bacteroidetes	C	nitroreductase	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_2662075_6	313596.RB2501_04090	1.382e-75	258.0	COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,1I3ED@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
CMS2_k127_2662075_7	313596.RB2501_04085	7.559e-54	194.0	COG0810@1|root,COG0810@2|Bacteria,4PKJV@976|Bacteroidetes,1IJB8@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2662075_4	313596.RB2501_04080	3.715e-103	336.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1HWX6@117743|Flavobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS2_k127_2662075_2	313596.RB2501_04075	2.722e-168	537.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1HWJX@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS2_k127_267407_4	313596.RB2501_00766	1.054e-57	205.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1HWNA@117743|Flavobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
CMS2_k127_267407_1	313596.RB2501_00761	1.651e-96	321.0	COG3595@1|root,COG3595@2|Bacteria,4NIA2@976|Bacteroidetes,1I0CY@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_267407_0	313596.RB2501_00756	7.223e-265	826.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
CMS2_k127_267407_3	1121875.KB907546_gene2744	4.014e-59	205.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1I2SA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
CMS2_k127_267407_2	313596.RB2501_00746	1.711e-64	224.0	COG1680@1|root,COG1680@2|Bacteria,4NQF7@976|Bacteroidetes,1I2XA@117743|Flavobacteriia	976|Bacteroidetes	V	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_267407_5	313596.RB2501_00741	1.28e-10	61.0	COG3296@1|root,COG3296@2|Bacteria,4NUD1@976|Bacteroidetes,1I4G4@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
CMS2_k127_2691593_1	313596.RB2501_12642	1.028e-146	468.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWVS@117743|Flavobacteriia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS2_k127_2691593_4	1250232.JQNJ01000001_gene2532	1.359e-55	199.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1I1AG@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS2_k127_2691593_3	313596.RB2501_12647	3.447e-68	235.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I1Y2@117743|Flavobacteriia	976|Bacteroidetes	O	Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS2_k127_2691593_2	313596.RB2501_12652	2.698e-95	316.0	2DI3V@1|root,32UAD@2|Bacteria,4NUQE@976|Bacteroidetes,1I2BK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2691593_0	313596.RB2501_12662	6.783e-228	709.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
CMS2_k127_2694430_2	313596.RB2501_09550	2.397e-110	361.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,1HZHT@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CMS2_k127_2694430_1	1121897.AUGO01000014_gene3466	1.413e-125	405.0	COG0235@1|root,COG0235@2|Bacteria,4NGMP@976|Bacteroidetes,1HYQV@117743|Flavobacteriia,2NU5E@237|Flavobacterium	976|Bacteroidetes	G	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS2_k127_2694430_0	1250232.JQNJ01000001_gene508	9.504e-257	798.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,1HYCR@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
CMS2_k127_2722615_1	1121875.KB907550_gene814	4.759e-129	417.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1HXF5@117743|Flavobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
CMS2_k127_2722615_2	313603.FB2170_03775	3.691e-101	334.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1ICAB@117743|Flavobacteriia,2PIJH@252356|Maribacter	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
CMS2_k127_2722615_0	1121011.AUCB01000002_gene445	2.871e-146	466.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia,23G8V@178469|Arenibacter	976|Bacteroidetes	P	Domain present in carbohydrate binding proteins and sugar hydrolses	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
CMS2_k127_2731387_3	1122621.ATZA01000051_gene2841	5.565e-70	243.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,1IP7E@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3533 conserved	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
CMS2_k127_2731387_1	313596.RB2501_13134	9.424e-284	878.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1HZ06@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS2_k127_2731387_2	313596.RB2501_13139	1.701e-106	349.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1HY30@117743|Flavobacteriia	976|Bacteroidetes	E	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase_phd,Peptidase_S9
CMS2_k127_2731387_0	313596.RB2501_13144	0.0	1628.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_2740705_0	313596.RB2501_00876	1.247e-245	768.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,1HY8Y@117743|Flavobacteriia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase concanavalin-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS2_k127_2742940_3	555500.I215_08652	5.99e-54	190.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia	976|Bacteroidetes	EF	ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS2_k127_2742940_1	1121875.KB907550_gene710	1.921e-91	304.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1HWZN@117743|Flavobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS2_k127_2742940_0	313596.RB2501_04970	5.01e-93	309.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS2_k127_2742940_2	313596.RB2501_04975	7.612e-83	280.0	COG4733@1|root,COG4733@2|Bacteria,4NQRS@976|Bacteroidetes,1I3C0@117743|Flavobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2742940_4	313596.RB2501_04980	1.1e-19	92.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
CMS2_k127_2752248_2	1443665.JACA01000041_gene1576	1.303e-125	406.0	COG0580@1|root,COG0580@2|Bacteria,4NFW4@976|Bacteroidetes,1HXX1@117743|Flavobacteriia,2YGRF@290174|Aquimarina	976|Bacteroidetes	G	Major intrinsic protein	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
CMS2_k127_2752248_1	1286632.P278_18360	2.376e-272	843.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS2_k127_2752248_0	313596.RB2501_09505	6.483e-316	972.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1HWMX@117743|Flavobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS2_k127_2782829_3	313596.RB2501_09660	4.929e-38	143.0	2EI2Y@1|root,33BUE@2|Bacteria,4NZ4J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2782829_2	313596.RB2501_09655	7.957e-109	358.0	COG1028@1|root,COG1028@2|Bacteria,4PKBF@976|Bacteroidetes,1IJ6G@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_2782829_1	313596.RB2501_09650	4.484e-135	437.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1HYWG@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS2_k127_2782829_0	313596.RB2501_09645	1.999e-142	454.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_2794067_0	1121875.KB907549_gene1886	1.52e-84	281.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,1HYVR@117743|Flavobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.7	ko:K01502	ko00643,ko01120,map00643,map01120	-	R05358	RC01336	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS2_k127_2794067_1	1250232.JQNJ01000001_gene1228	2.458e-78	282.0	COG0400@1|root,COG0400@2|Bacteria,4NJ8E@976|Bacteroidetes,1HXED@117743|Flavobacteriia	976|Bacteroidetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2864510_1	313596.RB2501_12934	4.262e-100	328.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS2_k127_2864510_0	313596.RB2501_12929	2.345e-142	456.0	COG1091@1|root,COG1091@2|Bacteria,4NF71@976|Bacteroidetes,1HZ17@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS2_k127_2864510_3	313596.RB2501_12919	2.951e-37	143.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1I40R@117743|Flavobacteriia	976|Bacteroidetes	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS2_k127_2864510_2	1197477.IA57_12585	6.125e-49	177.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1HY9V@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS2_k127_2871349_9	362418.IW19_05770	3.384e-55	194.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1I2X2@117743|Flavobacteriia,2NWT5@237|Flavobacterium	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
CMS2_k127_2871349_4	1120965.AUBV01000009_gene3003	1.069e-128	422.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,47M6K@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_2871349_11	1121875.KB907550_gene728	9.918e-17	85.0	2E6MW@1|root,3318G@2|Bacteria,4NWFR@976|Bacteroidetes,1I55U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2871349_3	313596.RB2501_08800	1.594e-132	430.0	COG4857@1|root,COG4857@2|Bacteria,4NHKI@976|Bacteroidetes,1I08V@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphotransferase enzyme family	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS2_k127_2871349_0	313596.RB2501_08795	1.055e-170	548.0	COG1397@1|root,COG1397@2|Bacteria,4NISQ@976|Bacteroidetes,1I112@117743|Flavobacteriia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS2_k127_2871349_10	313596.RB2501_08775	1.161e-23	100.0	2E6MW@1|root,3318G@2|Bacteria,4NWFR@976|Bacteroidetes,1I55U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2871349_7	313596.RB2501_08765	1.532e-78	267.0	COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,1I1FQ@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS2_k127_2871349_5	1004149.AFOE01000018_gene603	6.809e-123	398.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS2_k127_2871349_1	313596.RB2501_08755	1.695e-168	533.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1HYS0@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
CMS2_k127_2871349_6	313596.RB2501_08750	2.083e-82	281.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,1HY5E@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
CMS2_k127_2871349_8	1121875.KB907547_gene3061	9.561e-75	258.0	COG1215@1|root,COG1215@2|Bacteria,4NF6C@976|Bacteroidetes,1HYAR@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_2871349_2	313596.RB2501_08745	1.327e-149	478.0	COG0860@1|root,COG0860@2|Bacteria,4NHZA@976|Bacteroidetes,1HXWY@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CMS2_k127_2872821_1	313596.RB2501_03205	2.04e-114	372.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1HXCB@117743|Flavobacteriia	976|Bacteroidetes	S	UvrB UvrC	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
CMS2_k127_2872821_0	313596.RB2501_03200	1.459e-145	465.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS2_k127_2875493_3	643867.Ftrac_1861	1.661e-30	133.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
CMS2_k127_2875493_4	1209072.ALBT01000038_gene2455	1.393e-22	111.0	COG2207@1|root,COG2207@2|Bacteria,1R8G9@1224|Proteobacteria,1RZ2D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_2875493_2	1120965.AUBV01000014_gene1145	5.775e-40	159.0	2E3AK@1|root,2ZC5I@2|Bacteria,4NMX3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2875493_0	391603.FBALC1_03307	5.249e-115	391.0	29X8I@1|root,30IXV@2|Bacteria,4P0MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2875493_1	391603.FBALC1_03312	3.54e-73	257.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS2_k127_2887151_1	313596.RB2501_05705	2.063e-317	979.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1I09S@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS2_k127_2887151_2	313596.RB2501_05700	2.441e-233	722.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1HXJT@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS2_k127_2887151_6	313596.RB2501_05695	1.079e-118	385.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1HZDS@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_2887151_4	313596.RB2501_05690	5.749e-143	456.0	COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,1HYUY@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_2887151_5	313596.RB2501_05685	1.471e-125	408.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia	976|Bacteroidetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS2_k127_2887151_7	313596.RB2501_05680	1.858e-102	336.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1HXN2@117743|Flavobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS2_k127_2887151_8	313596.RB2501_05675	5.534e-101	333.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS2_k127_2887151_10	313596.RB2501_05670	6.339e-44	164.0	2E4DF@1|root,332AR@2|Bacteria,4NW43@976|Bacteroidetes,1I5T3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2887151_9	886377.Murru_1533	2.237e-79	272.0	2DBKF@1|root,2Z9SZ@2|Bacteria,4NFPX@976|Bacteroidetes,1HZFY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2887151_3	1484460.JSWG01000004_gene2564	2.404e-221	700.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,1HYFK@117743|Flavobacteriia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
CMS2_k127_2887151_0	886377.Murru_1534	0.0	1082.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia	976|Bacteroidetes	U	phosphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
CMS2_k127_2890186_2	1250232.JQNJ01000001_gene2245	8.905e-152	483.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
CMS2_k127_2890186_5	313596.RB2501_02745	1.502e-65	227.0	COG0517@1|root,COG0517@2|Bacteria,4NQYH@976|Bacteroidetes,1I24R@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS2_k127_2890186_3	313596.RB2501_02740	4.031e-101	333.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1HX41@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS2_k127_2890186_4	1122605.KB893625_gene1828	1.292e-70	243.0	COG2514@1|root,COG2514@2|Bacteria,4NMJC@976|Bacteroidetes,1ISH3@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS2_k127_2890186_1	313596.RB2501_02735	6.898e-176	552.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_2890186_0	313596.RB2501_02725	0.0	1263.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1HWNZ@117743|Flavobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS2_k127_2890532_2	313596.RB2501_15414	2.811e-68	233.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,1HYMD@117743|Flavobacteriia	976|Bacteroidetes	S	dehydrogenases and related proteins	gfo	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_2890532_1	313596.RB2501_15394	3.817e-106	349.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
CMS2_k127_2890532_0	313596.RB2501_15384	1.635e-108	354.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1HWJY@117743|Flavobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS2_k127_2897693_3	313596.RB2501_12964	1.393e-13	70.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS2_k127_2897693_2	313596.RB2501_12959	3.849e-66	228.0	2E3JI@1|root,32YHX@2|Bacteria,4NUTH@976|Bacteroidetes,1I59V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2897693_1	313596.RB2501_12954	5.955e-203	644.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1HXCP@117743|Flavobacteriia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS2_k127_2897693_0	313596.RB2501_12949	8.198e-257	800.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
CMS2_k127_2903639_0	313596.RB2501_06335	5.931e-266	822.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_2910891_2	313596.RB2501_11657	6.034e-137	439.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HZDJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_2910891_1	313596.RB2501_11662	4.566e-185	586.0	COG3920@1|root,COG3920@2|Bacteria,4NEMC@976|Bacteroidetes,1HZHX@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2
CMS2_k127_2910891_0	313596.RB2501_11667	0.0	1572.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS2_k127_291729_6	313596.RB2501_03355	7.087e-45	166.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1HXHN@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
CMS2_k127_291729_4	313596.RB2501_03360	2.815e-122	394.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,1HYC6@117743|Flavobacteriia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS2_k127_291729_1	313596.RB2501_03365	1.625e-253	796.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1HWJS@117743|Flavobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS2_k127_291729_3	313596.RB2501_03370	1.753e-171	583.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia	976|Bacteroidetes	FH	Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
CMS2_k127_291729_5	313596.RB2501_03375	1.44e-82	277.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia	976|Bacteroidetes	J	Methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CMS2_k127_291729_0	313596.RB2501_03380	0.0	1422.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS2_k127_291729_2	616991.JPOO01000001_gene3356	1.356e-193	610.0	COG0477@1|root,COG0607@1|root,COG0607@2|Bacteria,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,1HZ4T@117743|Flavobacteriia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_2953435_4	313596.RB2501_01525	4.037e-38	145.0	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,1I3TU@117743|Flavobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS2_k127_2953435_2	313596.RB2501_01520	1.934e-127	418.0	COG1082@1|root,COG1082@2|Bacteria,4NIDT@976|Bacteroidetes,1I800@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_2953435_1	1121875.KB907546_gene2713	1.093e-219	689.0	COG2610@1|root,COG2610@2|Bacteria,4NFQH@976|Bacteroidetes,1I149@117743|Flavobacteriia	976|Bacteroidetes	EG	GntP family permease	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
CMS2_k127_2953435_0	1121875.KB907546_gene2712	0.0	1022.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,1HYTD@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_2953435_3	1250232.JQNJ01000001_gene431	1.226e-49	181.0	2C0KK@1|root,33JVZ@2|Bacteria,4NZH9@976|Bacteroidetes,1I84C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2959783_3	313596.RB2501_13129	3.187e-148	495.0	COG1629@1|root,COG1629@2|Bacteria,4PMAR@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CMS2_k127_2959783_1	313596.RB2501_13124	3.992e-185	582.0	COG2159@1|root,COG2159@2|Bacteria,4NK6T@976|Bacteroidetes,1I2BN@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS2_k127_2959783_0	313596.RB2501_13119	5.116e-234	751.0	COG1231@1|root,COG1231@2|Bacteria,4PMAQ@976|Bacteroidetes,1IMSK@117743|Flavobacteriia	976|Bacteroidetes	E	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
CMS2_k127_2959783_5	1336803.PHEL49_0743	2.525e-42	161.0	2A813@1|root,30X1F@2|Bacteria,4NP0A@976|Bacteroidetes,1I2B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2959783_6	1249997.JHZW01000003_gene3372	3.072e-18	87.0	2E7YU@1|root,332D8@2|Bacteria,4NV36@976|Bacteroidetes,1I554@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2959783_4	1286632.P278_20790	1.539e-50	184.0	COG1393@1|root,COG1393@2|Bacteria,4NSWE@976|Bacteroidetes,1I56N@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
CMS2_k127_2959783_2	926559.JoomaDRAFT_2671	4.711e-168	535.0	2CDRA@1|root,2Z7QN@2|Bacteria,4NHVB@976|Bacteroidetes,1HZZX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2965490_0	313596.RB2501_16179	4.464e-133	428.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CMS2_k127_2965490_4	313596.RB2501_16184	4.504e-77	271.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1HYRJ@117743|Flavobacteriia	976|Bacteroidetes	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
CMS2_k127_2965490_2	313596.RB2501_00005	1.027e-122	402.0	COG3828@1|root,COG3828@2|Bacteria,4NHIY@976|Bacteroidetes,1HYIS@117743|Flavobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS2_k127_2965490_3	313596.RB2501_16204	9.633e-90	300.0	COG1272@1|root,COG1272@2|Bacteria,4NM95@976|Bacteroidetes,1HYZQ@117743|Flavobacteriia	976|Bacteroidetes	S	membrane protein, hemolysin III homolog	hly-III	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS2_k127_2965490_1	313596.RB2501_16209	9.672e-128	408.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,1HZDE@117743|Flavobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_2972559_1	313596.RB2501_07180	6.318e-28	115.0	2E3AK@1|root,320TI@2|Bacteria,4NRX2@976|Bacteroidetes,1I3SJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2972559_0	313596.RB2501_00576	0.0	1253.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_2986103_2	313596.RB2501_06365	4.133e-120	388.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1HWPS@117743|Flavobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS2_k127_2986103_0	313596.RB2501_06370	0.0	1269.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia	976|Bacteroidetes	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS2_k127_2986103_1	313596.RB2501_06375	3.39e-142	453.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1HYVV@117743|Flavobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CMS2_k127_2991760_4	313596.RB2501_04070	7.952e-73	250.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS2_k127_2991760_7	1121898.Q766_20910	2.604e-45	166.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia,2NWU9@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
CMS2_k127_2991760_3	313596.RB2501_04060	4.74e-97	325.0	28JKT@1|root,2Z9DG@2|Bacteria,4NJJK@976|Bacteroidetes,1HYPI@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
CMS2_k127_2991760_5	313596.RB2501_04055	6.178e-60	210.0	2C85M@1|root,31GSX@2|Bacteria,4NQEM@976|Bacteroidetes,1I48Z@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Stress responsive alpha-beta barrel	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS2_k127_2991760_6	313596.RB2501_04050	1.052e-51	184.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1I2YP@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS2_k127_2991760_2	313596.RB2501_04040	2.964e-176	559.0	COG4192@1|root,COG4192@2|Bacteria,4NFY7@976|Bacteroidetes,1HX1N@117743|Flavobacteriia	976|Bacteroidetes	T	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
CMS2_k127_2991760_1	313596.RB2501_04025	1.786e-247	769.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1HX16@117743|Flavobacteriia	976|Bacteroidetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_2991760_0	313596.RB2501_04020	0.0	1095.0	COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
CMS2_k127_2997196_1	313596.RB2501_02195	6.756e-147	466.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1HXSE@117743|Flavobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS2_k127_2997196_4	1249997.JHZW01000003_gene3655	1.529e-91	306.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1HWU0@117743|Flavobacteriia,2PH1P@252356|Maribacter	976|Bacteroidetes	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS2_k127_2997196_0	313596.RB2501_02205	1.639e-165	527.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1HY2Y@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS2_k127_2997196_3	313596.RB2501_02210	1.084e-97	325.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1HYHC@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS2_k127_2997196_5	313596.RB2501_02215	3.184e-74	258.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1I1CD@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS2_k127_2997196_2	886377.Murru_2135	1.984e-123	398.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_3015687_2	1123234.AUKI01000013_gene1590	2.032e-05	48.0	COG4319@1|root,COG4319@2|Bacteria,4NT0G@976|Bacteroidetes,1I4DA@117743|Flavobacteriia	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
CMS2_k127_3015687_1	388413.ALPR1_02070	3.57e-66	229.0	COG2080@1|root,COG2080@2|Bacteria,4NPVY@976|Bacteroidetes	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_3015687_0	616991.JPOO01000003_gene1728	1.293e-310	963.0	COG1529@1|root,COG1529@2|Bacteria,4NG6Q@976|Bacteroidetes,1IIS1@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_3042728_2	313596.RB2501_15969	1.007e-109	363.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS2_k127_3042728_1	313596.RB2501_15964	1.112e-123	402.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,1HXZR@117743|Flavobacteriia	976|Bacteroidetes	J	Ion transporter	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS2_k127_3042728_0	313596.RB2501_15959	5.702e-156	500.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,1HWK3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
CMS2_k127_3042728_3	313596.RB2501_15954	4.679e-58	204.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS2_k127_3047087_2	1121875.KB907547_gene2900	9.464e-63	220.0	299NP@1|root,2ZWR1@2|Bacteria,4NP8Q@976|Bacteroidetes,1I269@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3047087_1	1250232.JQNJ01000001_gene744	8.557e-146	466.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS2_k127_3047087_0	313596.RB2501_09165	2.14e-247	769.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HWXA@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS2_k127_3047087_3	319225.Plut_1185	3.876e-08	55.0	COG3876@1|root,COG3876@2|Bacteria,1FDF0@1090|Chlorobi	1090|Chlorobi	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS2_k127_3053538_6	313596.RB2501_11487	6.363e-27	112.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1I2XJ@117743|Flavobacteriia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS2_k127_3053538_1	313596.RB2501_11482	5.766e-148	472.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CMS2_k127_3053538_2	313596.RB2501_11477	2.036e-124	403.0	COG1216@1|root,COG1216@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_3053538_4	313603.FB2170_00840	2.238e-72	248.0	COG3475@1|root,COG3475@2|Bacteria,4NWA7@976|Bacteroidetes,1I7WP@117743|Flavobacteriia	976|Bacteroidetes	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
CMS2_k127_3053538_5	616991.JPOO01000001_gene4340	1.792e-64	228.0	COG0615@1|root,COG0615@2|Bacteria,4NM8I@976|Bacteroidetes,1I5SQ@117743|Flavobacteriia	976|Bacteroidetes	IM	Cytidylyltransferase-like	aepX	-	2.7.7.39,5.4.2.9	ko:K00980,ko:K01841	ko00440,ko00564,ko01100,ko01120,ko01130,map00440,map00564,map01100,map01120,map01130	-	R00661,R00856	RC00002,RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,PEP_mutase
CMS2_k127_3053538_3	616991.JPOO01000001_gene4336	6.962e-102	336.0	COG1213@1|root,COG1213@2|Bacteria,4NF7V@976|Bacteroidetes,1I0N7@117743|Flavobacteriia	976|Bacteroidetes	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS2_k127_3053538_0	616991.JPOO01000001_gene4335	2.5e-154	497.0	COG1216@1|root,COG1887@1|root,COG1216@2|Bacteria,COG1887@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia,23G85@178469|Arenibacter	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
CMS2_k127_3071697_9	313596.RB2501_02405	5.632e-98	323.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,1HY9X@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS2_k127_3071697_6	313596.RB2501_02410	3.762e-129	419.0	COG5343@1|root,COG5343@2|Bacteria,4NH0S@976|Bacteroidetes,1HY07@117743|Flavobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
CMS2_k127_3071697_13	1286632.P278_02670	9.338e-27	111.0	2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,1I51R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3071697_12	313596.RB2501_02420	2.173e-75	258.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,1I19Q@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_3071697_2	313596.RB2501_02425	4.348e-171	539.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1HXXW@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS2_k127_3071697_4	313596.RB2501_02430	1.081e-162	517.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HXVU@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS2_k127_3071697_0	313596.RB2501_02435	1.253e-317	988.0	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
CMS2_k127_3071697_8	313596.RB2501_02440	9.179e-115	378.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS2_k127_3071697_3	313596.RB2501_02445	5.764e-164	522.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1HXRQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS2_k127_3071697_5	313596.RB2501_02450	4.958e-141	451.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS2_k127_3071697_1	313596.RB2501_02455	2.052e-253	786.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia	976|Bacteroidetes	CH	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS2_k127_3071697_11	313596.RB2501_02475	7.534e-97	327.0	COG0740@1|root,COG0740@2|Bacteria,4NF77@976|Bacteroidetes,1HXAR@117743|Flavobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS2_k127_3071697_10	313596.RB2501_02480	7.252e-98	326.0	28NPC@1|root,2ZBPA@2|Bacteria,4NMF8@976|Bacteroidetes,1I1A0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3071697_7	313596.RB2501_02485	1.11e-127	413.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1I0Z6@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_3076749_3	313596.RB2501_03825	1.004e-28	118.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,1HXD0@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CMS2_k127_3076749_1	313596.RB2501_03830	3.979e-135	432.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS2_k127_3076749_2	1121875.KB907550_gene878	1.845e-86	289.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1HYRH@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS2_k127_3076749_0	313596.RB2501_03840	2.335e-173	549.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS2_k127_3077180_0	1121875.KB907547_gene2932	7.117e-179	571.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1I1R3@117743|Flavobacteriia	976|Bacteroidetes	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CMS2_k127_3077180_1	313596.RB2501_03090	8.555e-127	416.0	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes,1I0SG@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_3077180_2	313596.RB2501_03095	7.888e-95	319.0	28PIV@1|root,2ZC8P@2|Bacteria,4NGE2@976|Bacteroidetes,1I08D@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_3077180_3	313596.RB2501_03100	9.308e-48	171.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
CMS2_k127_3096460_1	313596.RB2501_03970	1.282e-173	548.0	COG1593@1|root,COG1593@2|Bacteria,4NE5T@976|Bacteroidetes,1HX6G@117743|Flavobacteriia	976|Bacteroidetes	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS2_k127_3096460_0	313596.RB2501_03965	9.857e-242	752.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1HYH2@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_3096460_2	313596.RB2501_03960	2.464e-65	224.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1HZMA@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_3097381_3	313596.RB2501_13654	1.637e-118	389.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1HX0Y@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CMS2_k127_3097381_2	313596.RB2501_13649	1.805e-130	428.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1HX64@117743|Flavobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS2_k127_3097381_7	1121875.KB907556_gene579	6.538e-44	160.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1I43K@117743|Flavobacteriia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS2_k127_3097381_4	313596.RB2501_13639	7.534e-108	350.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1HXJN@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS2_k127_3097381_5	313596.RB2501_13634	9.515e-93	315.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1HYPS@117743|Flavobacteriia	976|Bacteroidetes	EH	Aminotransferase class IV	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS2_k127_3097381_6	313596.RB2501_13629	1.269e-65	226.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS2_k127_3097381_0	1121875.KB907549_gene1898	2.239e-195	638.0	COG1983@1|root,COG5373@1|root,COG1983@2|Bacteria,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1HZB4@117743|Flavobacteriia	976|Bacteroidetes	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS2_k127_3097381_1	313596.RB2501_13609	3.503e-147	477.0	COG2905@1|root,COG2905@2|Bacteria,4NDZ8@976|Bacteroidetes,1HWQU@117743|Flavobacteriia	976|Bacteroidetes	T	signal-transduction protein containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS2_k127_3108123_2	313596.RB2501_00831	8.855e-76	258.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1HX1F@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde	-	-	1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220	-	R00264,R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS2_k127_3108123_0	555500.I215_10425	5.802e-236	742.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS2_k127_3108123_1	313596.RB2501_00826	5.931e-95	317.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1HY93@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
CMS2_k127_3109835_0	313596.RB2501_15024	1.112e-234	746.0	COG0457@1|root,COG1368@1|root,COG0457@2|Bacteria,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS2_k127_3109835_1	313596.RB2501_15019	2.19e-146	473.0	COG0457@1|root,COG0457@2|Bacteria,4NGMH@976|Bacteroidetes,1HZM6@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_19
CMS2_k127_311353_3	313596.RB2501_08335	3.615e-99	327.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS2_k127_311353_5	313596.RB2501_08340	2.332e-40	154.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1I3ZS@117743|Flavobacteriia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS2_k127_311353_0	313596.RB2501_08345	2.288e-311	958.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS2_k127_311353_2	313596.RB2501_08350	3.218e-149	473.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1HWMQ@117743|Flavobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS2_k127_311353_4	313596.RB2501_08355	6.302e-77	263.0	28QB8@1|root,2ZCTU@2|Bacteria,4NP7R@976|Bacteroidetes,1I1M5@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
CMS2_k127_311353_1	313596.RB2501_08360	1.243e-209	663.0	COG1807@1|root,COG1807@2|Bacteria,4NEU7@976|Bacteroidetes,1HZQP@117743|Flavobacteriia	976|Bacteroidetes	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS2_k127_3131135_2	1004149.AFOE01000048_gene35	1.116e-22	102.0	2E6K6@1|root,3316Y@2|Bacteria,4NT3A@976|Bacteroidetes,1I409@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3131135_0	313596.RB2501_14779	1.551e-90	307.0	28PY8@1|root,2ZCHZ@2|Bacteria,4NMGG@976|Bacteroidetes,1I1JV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3131135_1	313596.RB2501_14784	1.443e-84	287.0	COG0793@1|root,COG4976@1|root,COG0793@2|Bacteria,COG4976@2|Bacteria,4NIS9@976|Bacteroidetes,1HZR4@117743|Flavobacteriia	976|Bacteroidetes	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS2_k127_3136224_3	761193.Runsl_0033	2.086e-57	205.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,47JIU@768503|Cytophagia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS2_k127_3136224_8	1121012.AUKX01000010_gene1953	2.132e-12	74.0	2EATR@1|root,334VH@2|Bacteria,4NWVE@976|Bacteroidetes,1I58X@117743|Flavobacteriia,23HP5@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3136224_2	1121007.AUML01000033_gene2788	2.445e-130	424.0	COG0683@1|root,COG0683@2|Bacteria,4NIVQ@976|Bacteroidetes,1HZ6K@117743|Flavobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3136224_0	398720.MED217_17130	0.0	1021.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,2XJHM@283735|Leeuwenhoekiella	976|Bacteroidetes	F	Ribonucleotide reductase, barrel domain	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS2_k127_3136224_1	504487.JCM19302_1469	6.272e-228	710.0	COG0208@1|root,COG0208@2|Bacteria,4NGDD@976|Bacteroidetes,1HY1Y@117743|Flavobacteriia	976|Bacteroidetes	F	Ribonucleotide Reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_sm
CMS2_k127_3136224_4	1121875.KB907550_gene727	6.803e-47	172.0	2DDNY@1|root,2ZIRM@2|Bacteria,4P8P6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3136224_6	1121104.AQXH01000001_gene1547	6.416e-32	134.0	2E3AK@1|root,32YA3@2|Bacteria,4PAQ0@976|Bacteroidetes,1IZWF@117747|Sphingobacteriia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3136224_7	1121875.KB907547_gene3032	9.783e-20	91.0	2E3AK@1|root,2ZC4K@2|Bacteria,4NMMM@976|Bacteroidetes,1I1F6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3147250_1	313596.RB2501_01890	4.811e-266	824.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS2_k127_3147250_2	445961.IW15_03185	3.086e-10	66.0	COG3637@1|root,COG3637@2|Bacteria,4NRZ4@976|Bacteroidetes,1I2ZK@117743|Flavobacteriia,3ZRPK@59732|Chryseobacterium	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3147250_0	886377.Murru_2196	0.0	1084.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXUG@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
CMS2_k127_3188602_0	313596.RB2501_12672	0.0	1021.0	COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,1HZ0S@117743|Flavobacteriia	976|Bacteroidetes	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
CMS2_k127_3188602_1	313596.RB2501_12662	1.304e-42	157.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
CMS2_k127_3207685_0	313596.RB2501_11437	9.516e-203	633.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1HYBW@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleoid-associated protein NdpA	-	-	-	-	-	-	-	-	-	-	-	-	NA37
CMS2_k127_3207685_2	313596.RB2501_11442	7.708e-76	269.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1I189@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CMS2_k127_3207685_1	313596.RB2501_11447	5.63e-153	492.0	COG1612@1|root,COG1612@2|Bacteria,4NEBR@976|Bacteroidetes,1HWUP@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS2_k127_3207685_3	1123234.AUKI01000024_gene2160	1.396e-18	85.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1HX65@117743|Flavobacteriia	976|Bacteroidetes	J	TRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS2_k127_3247766_1	313603.FB2170_11866	2.605e-155	496.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1HZCI@117743|Flavobacteriia,2PGP9@252356|Maribacter	976|Bacteroidetes	P	Integral membrane protein TerC family	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CMS2_k127_3247766_0	313596.RB2501_14764	7.773e-188	594.0	COG0477@1|root,COG2814@2|Bacteria,4NG6X@976|Bacteroidetes,1HY2F@117743|Flavobacteriia	976|Bacteroidetes	EGP	Drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K03446,ko:K07552	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.2,2.A.1.3	-	-	MFS_1
CMS2_k127_3281_6	1121875.KB907551_gene1056	5.158e-66	227.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,1HXN8@117743|Flavobacteriia	976|Bacteroidetes	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
CMS2_k127_3281_8	313596.RB2501_06920	2.912e-52	189.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,1I23R@117743|Flavobacteriia	976|Bacteroidetes	S	(GNAT) family	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
CMS2_k127_3281_7	313596.RB2501_06925	1.653e-60	211.0	2AMQ7@1|root,31CKD@2|Bacteria,4NQVK@976|Bacteroidetes,1I2S8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3281_3	313596.RB2501_06930	4.069e-180	569.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1I009@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_3281_0	313596.RB2501_06935	0.0	1026.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1HZK3@117743|Flavobacteriia	976|Bacteroidetes	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
CMS2_k127_3281_5	313596.RB2501_06940	1.153e-80	279.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1HZ3G@117743|Flavobacteriia	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CMS2_k127_3281_4	313596.RB2501_06945	1.189e-114	377.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1HYHP@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrroloquinoline quinone biosynthesis protein PqqB	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
CMS2_k127_3281_1	313596.RB2501_06950	1.57e-271	843.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1HYZ4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS2_k127_3281_9	143224.JQMD01000002_gene3120	6.272e-30	123.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1I41Y@117743|Flavobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS2_k127_3281_2	313596.RB2501_06960	3.497e-208	653.0	COG0517@1|root,COG3572@1|root,COG0517@2|Bacteria,COG3572@2|Bacteria,4NGW0@976|Bacteroidetes,1HYC5@117743|Flavobacteriia	976|Bacteroidetes	H	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
CMS2_k127_3300997_0	313596.RB2501_02635	2.701e-219	686.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
CMS2_k127_3300997_1	313596.RB2501_02640	1.404e-134	439.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,1HXB0@117743|Flavobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
CMS2_k127_3300997_2	313596.RB2501_02645	3.386e-74	250.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1I21R@117743|Flavobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS2_k127_3300997_3	313596.RB2501_02650	5.473e-08	53.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1HYV0@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
CMS2_k127_3347119_4	1121875.KB907547_gene3271	2.358e-49	176.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS2_k127_3347119_2	313596.RB2501_07810	3.104e-63	224.0	2CHIM@1|root,332W8@2|Bacteria,4NWW0@976|Bacteroidetes,1I5A9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3347119_1	313596.RB2501_07815	4.949e-108	352.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1HYAA@117743|Flavobacteriia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS2_k127_3347119_3	313596.RB2501_07820	3.412e-60	213.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS2_k127_3347119_0	313596.RB2501_07830	4.879e-277	857.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS2_k127_3362605_0	313596.RB2501_14289	5.468e-320	987.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS2_k127_3362605_1	313596.RB2501_14284	1.014e-29	119.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1HX3V@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
CMS2_k127_3383242_6	688270.Celal_0103	5.749e-56	198.0	COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,1I24N@117743|Flavobacteriia,1F9AY@104264|Cellulophaga	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS2_k127_3383242_1	313596.RB2501_00401	4.236e-308	952.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1HXQU@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS2_k127_3383242_9	388413.ALPR1_19898	6.952e-42	158.0	COG2318@1|root,COG2318@2|Bacteria,4NSEY@976|Bacteroidetes,47RM1@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS2_k127_3383242_0	313596.RB2501_00386	0.0	2046.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CMS2_k127_3383242_3	313596.RB2501_00381	1.238e-182	580.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1HXH7@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
CMS2_k127_3383242_4	313596.RB2501_00376	2.923e-135	438.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,1HWUF@117743|Flavobacteriia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
CMS2_k127_3383242_10	313596.RB2501_00371	1.303e-38	151.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3383242_7	313596.RB2501_00366	6.138e-49	179.0	2E7DN@1|root,331WR@2|Bacteria,4NVC6@976|Bacteroidetes,1I4D2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3383242_5	313596.RB2501_00361	3.367e-80	271.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1I18Y@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_3383242_2	313596.RB2501_00356	3.286e-240	748.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS2_k127_3391908_7	313596.RB2501_07600	1.882e-81	278.0	COG0457@1|root,COG3103@1|root,COG0457@2|Bacteria,COG3103@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
CMS2_k127_3391908_0	313596.RB2501_07605	5.179e-288	893.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
CMS2_k127_3391908_6	313596.RB2501_07610	6.045e-94	315.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia	976|Bacteroidetes	H	tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS2_k127_3391908_3	313596.RB2501_07615	3.092e-180	568.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS2_k127_3391908_4	313596.RB2501_07620	2.523e-177	560.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1HWY3@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CMS2_k127_3391908_1	313596.RB2501_07625	7.723e-224	716.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3391908_5	313596.RB2501_07630	1.396e-158	502.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS2_k127_3391908_2	313596.RB2501_07635	1.255e-187	589.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS2_k127_339214_7	313596.RB2501_15444	2.944e-21	94.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia	976|Bacteroidetes	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_339214_6	616991.JPOO01000003_gene733	5.437e-42	156.0	COG4818@1|root,COG4818@2|Bacteria,4NUVP@976|Bacteroidetes,1I44F@117743|Flavobacteriia,23HBI@178469|Arenibacter	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_339214_3	313596.RB2501_15454	2.125e-88	299.0	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,1HXVK@117743|Flavobacteriia	976|Bacteroidetes	S	Phospholipase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS2_k127_339214_4	313596.RB2501_15459	4.202e-74	252.0	2CEU1@1|root,32S0H@2|Bacteria,4NM9W@976|Bacteroidetes,1I2DG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_339214_1	313596.RB2501_15464	2.2e-130	419.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1HX58@117743|Flavobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS2_k127_339214_0	313596.RB2501_15469	8.588e-292	898.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_339214_5	313596.RB2501_15474	1.34e-73	250.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia	976|Bacteroidetes	O	Thiol peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS2_k127_339214_2	313596.RB2501_15479	1.088e-108	355.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1HX6E@117743|Flavobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS2_k127_3400943_0	313596.RB2501_11452	6.071e-224	699.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1HX65@117743|Flavobacteriia	976|Bacteroidetes	J	TRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS2_k127_3400943_1	313596.RB2501_11457	1.077e-86	289.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,1HZTW@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
CMS2_k127_3400943_2	313603.FB2170_00855	3.649e-17	82.0	COG1216@1|root,COG1887@1|root,COG1216@2|Bacteria,COG1887@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia,2PGDM@252356|Maribacter	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
CMS2_k127_3416060_4	313596.RB2501_01570	4.884e-151	484.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1HWX7@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS2_k127_3416060_3	616991.JPOO01000001_gene4388	6.234e-158	516.0	COG1472@1|root,COG1472@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia,23GHR@178469|Arenibacter	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3
CMS2_k127_3416060_1	313596.RB2501_01560	6.487e-232	722.0	COG0477@1|root,COG2814@2|Bacteria,4NG5F@976|Bacteroidetes,1HZCC@117743|Flavobacteriia	976|Bacteroidetes	EGP	Major Facilitator	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CMS2_k127_3416060_0	313596.RB2501_01555	0.0	1177.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1HYUH@117743|Flavobacteriia	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
CMS2_k127_3416060_6	313596.RB2501_01550	3.209e-134	430.0	COG1349@1|root,COG1349@2|Bacteria,4NE7U@976|Bacteroidetes,1HZX7@117743|Flavobacteriia	976|Bacteroidetes	K	COG1349 Transcriptional regulators of sugar metabolism	glcR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
CMS2_k127_3416060_5	313596.RB2501_01545	2.399e-145	464.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
CMS2_k127_3416060_2	313596.RB2501_01540	3.449e-192	604.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,1HXFV@117743|Flavobacteriia	976|Bacteroidetes	G	Glucose sorbosone	gdhB	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
CMS2_k127_3429039_0	313596.RB2501_15929	7.172e-112	366.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS2_k127_3429039_3	1121011.AUCB01000024_gene3296	4.735e-72	245.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1I191@117743|Flavobacteriia,23FWT@178469|Arenibacter	976|Bacteroidetes	O	SmpB protein	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS2_k127_3429039_2	313596.RB2501_15919	1.097e-96	321.0	28JI1@1|root,2Z9BG@2|Bacteria,4NMDW@976|Bacteroidetes,1I1PA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3429039_4	616991.JPOO01000003_gene839	7.966e-59	209.0	COG0406@1|root,COG0406@2|Bacteria,4NQWA@976|Bacteroidetes,1I38J@117743|Flavobacteriia,23H6H@178469|Arenibacter	976|Bacteroidetes	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS2_k127_3429039_1	313596.RB2501_15909	2.26e-108	368.0	COG3064@1|root,COG3064@2|Bacteria,4NJ62@976|Bacteroidetes,1HZKK@117743|Flavobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_3492256_0	313596.RB2501_03615	0.0	1553.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CMS2_k127_3492256_8	313596.RB2501_03620	1.001e-96	319.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS2_k127_3492256_1	313596.RB2501_03625	0.0	1269.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1HXS7@117743|Flavobacteriia	976|Bacteroidetes	C	Malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS2_k127_3492256_3	313596.RB2501_03635	1.783e-257	798.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
CMS2_k127_3492256_5	313596.RB2501_03640	2.073e-160	509.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS2_k127_3492256_10	313596.RB2501_03645	2.557e-72	248.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1I33C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_3492256_11	886377.Murru_1863	8.601e-51	183.0	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes,1I4Q6@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
CMS2_k127_3492256_7	886377.Murru_1862	5.554e-102	335.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,1I0EY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3492256_6	886377.Murru_1861	1.332e-132	432.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1HZDH@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_3492256_4	313596.RB2501_03660	1.629e-196	615.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1HX4Q@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS2_k127_3492256_2	313596.RB2501_03670	1.458e-307	946.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS2_k127_3492256_9	313596.RB2501_03680	2.271e-73	259.0	COG1664@1|root,COG1664@2|Bacteria,4NMVQ@976|Bacteroidetes,1I1WV@117743|Flavobacteriia	976|Bacteroidetes	M	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS2_k127_3492256_12	1286632.P278_23360	1.446e-21	93.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS2_k127_3494292_4	926559.JoomaDRAFT_1237	6.004e-89	305.0	COG2819@1|root,COG2819@2|Bacteria,4NGAG@976|Bacteroidetes,1HZR3@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	CBM_20,Esterase
CMS2_k127_3494292_9	1120966.AUBU01000022_gene3014	4.216e-26	117.0	2C312@1|root,2Z7N1@2|Bacteria,4NFNW@976|Bacteroidetes,47UK9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3494292_1	313596.RB2501_05505	8.875e-246	763.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS2_k127_3494292_3	313596.RB2501_05510	5.728e-113	368.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS2_k127_3494292_8	1121875.KB907553_gene38	1.068e-31	124.0	COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,1I54J@117743|Flavobacteriia	976|Bacteroidetes	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS2_k127_3494292_0	313596.RB2501_05520	0.0	1185.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1HXDK@117743|Flavobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
CMS2_k127_3494292_10	1121011.AUCB01000006_gene1066	7.917e-07	52.0	2ACEC@1|root,311ZV@2|Bacteria,4PGUS@976|Bacteroidetes,1IFRN@117743|Flavobacteriia,23IHI@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3494292_7	313596.RB2501_05530	6.732e-37	144.0	COG4206@1|root,COG4206@2|Bacteria,4PHBK@976|Bacteroidetes,1IBU8@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CMS2_k127_3494292_6	313596.RB2501_05535	1.164e-44	165.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,1I45Z@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
CMS2_k127_3494292_5	313596.RB2501_05540	1.877e-53	191.0	2DXDA@1|root,32V39@2|Bacteria,4NTBE@976|Bacteroidetes,1I4BN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3494292_2	1250232.JQNJ01000001_gene1509	3.459e-160	507.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_3499851_2	313596.RB2501_01046	3.574e-40	149.0	COG1917@1|root,COG1917@2|Bacteria,4NNR7@976|Bacteroidetes,1I1YT@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_3499851_1	313596.RB2501_01016	4.485e-88	291.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1I17D@117743|Flavobacteriia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_3499851_0	1121012.AUKX01000056_gene1661	0.0	1105.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia,23HRA@178469|Arenibacter	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_3499851_3	886377.Murru_0516	8.272e-33	128.0	2C0KK@1|root,33JVZ@2|Bacteria,4NZH9@976|Bacteroidetes,1I84C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3500722_0	313596.RB2501_14379	3.732e-153	492.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_3521909_4	886377.Murru_0451	1.821e-19	89.0	29EPR@1|root,301MK@2|Bacteria,4NQPA@976|Bacteroidetes,1I2MQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3521909_3	1121011.AUCB01000003_gene2516	3.086e-93	317.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1HWJW@117743|Flavobacteriia,23H1T@178469|Arenibacter	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS2_k127_3521909_2	616991.JPOO01000003_gene2298	9.663e-122	396.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1HXP0@117743|Flavobacteriia,23GNP@178469|Arenibacter	976|Bacteroidetes	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS2_k127_3521909_1	313603.FB2170_00470	1.296e-130	421.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1HX62@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS2_k127_3521909_0	313596.RB2501_09590	1.955e-236	741.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,1HYGZ@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	DUF4980,Glyco_hydro_32C,Glyco_hydro_32N
CMS2_k127_3531934_9	641526.ADIWIN_3602	2.516e-47	173.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1HWQ2@117743|Flavobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_3531934_8	313596.RB2501_15129	5.278e-57	203.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I37G@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS2_k127_3531934_4	313596.RB2501_15124	1.318e-126	409.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,1HWXB@117743|Flavobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_3531934_6	313596.RB2501_15119	1.374e-88	296.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1HXHW@117743|Flavobacteriia	976|Bacteroidetes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
CMS2_k127_3531934_1	313596.RB2501_15114	6.709e-224	696.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1HWJG@117743|Flavobacteriia	976|Bacteroidetes	S	protein with a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS2_k127_3531934_0	313596.RB2501_15109	2.878e-259	805.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1HX9Z@117743|Flavobacteriia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
CMS2_k127_3531934_7	313596.RB2501_15104	8.938e-60	211.0	2AT1D@1|root,31IHB@2|Bacteria,4NRT6@976|Bacteroidetes,1I3QM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3531934_2	313596.RB2501_15094	1.971e-151	486.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS2_k127_3531934_3	313596.RB2501_15079	1.863e-147	471.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1HXVM@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_3531934_5	313603.FB2170_11206	8.29e-126	406.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1HWYR@117743|Flavobacteriia,2PGX8@252356|Maribacter	976|Bacteroidetes	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS2_k127_3554288_3	313596.RB2501_07280	6.451e-51	181.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia	976|Bacteroidetes	S	transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_3554288_2	313596.RB2501_07275	3.717e-92	305.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia	976|Bacteroidetes	S	YeeE YedE family	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_3554288_0	313596.RB2501_07270	1.914e-221	691.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,1HZW9@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_3554288_1	1121875.KB907546_gene2729	2.681e-163	519.0	COG2041@1|root,COG2041@2|Bacteria,4NEIQ@976|Bacteroidetes,1I0IA@117743|Flavobacteriia	976|Bacteroidetes	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS2_k127_3557496_0	313596.RB2501_00076	0.0	1179.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS2_k127_3557496_1	1121875.KB907546_gene2852	8.226e-136	434.0	COG3279@1|root,COG3279@2|Bacteria,4NFN4@976|Bacteroidetes,1HYAZ@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS2_k127_3557496_2	313596.RB2501_00066	1.465e-62	217.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1I21M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS2_k127_3557496_3	1121875.KB907546_gene2854	2.201e-46	168.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1I2TD@117743|Flavobacteriia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS2_k127_3571107_1	313596.RB2501_11632	2.507e-95	314.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1I15K@117743|Flavobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
CMS2_k127_3571107_0	313596.RB2501_11637	0.0	1330.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_3575073_11	313596.RB2501_02315	1.508e-41	153.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1I1ZH@117743|Flavobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS2_k127_3575073_1	313596.RB2501_02320	0.0	1218.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS2_k127_3575073_7	313596.RB2501_02325	5.693e-101	331.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1HZ9W@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
CMS2_k127_3575073_5	313596.RB2501_02330	1.512e-132	427.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1HXPT@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS2_k127_3575073_9	504487.JCM19302_3104	1.449e-72	250.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1HXNW@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS2_k127_3575073_12	313596.RB2501_02340	3.983e-34	133.0	COG4281@1|root,COG4281@2|Bacteria	2|Bacteria	I	acyl-coa-binding protein	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	ACBP
CMS2_k127_3575073_6	313596.RB2501_02345	3.929e-129	415.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,1HYAH@117743|Flavobacteriia	976|Bacteroidetes	S	Creatinine amidohydrolase	crnA	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS2_k127_3575073_2	313596.RB2501_02350	3.12e-220	689.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1I0AT@117743|Flavobacteriia	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_3575073_8	926559.JoomaDRAFT_0646	1.787e-83	284.0	COG0745@1|root,COG0745@2|Bacteria,4NMAC@976|Bacteroidetes,1I1ST@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_3575073_3	313596.RB2501_02365	2.384e-193	611.0	COG0642@1|root,COG2205@2|Bacteria,4PMA5@976|Bacteroidetes,1IJP9@117743|Flavobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_3575073_4	313596.RB2501_02375	1.599e-192	608.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,1I0KC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS2_k127_3575073_0	313596.RB2501_02380	0.0	1535.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS2_k127_3575073_10	313596.RB2501_02385	7.865e-66	227.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS2_k127_3582010_3	1207076.ALAT01000184_gene2778	3.317e-26	109.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,1RYFE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Mandelate Racemase Muconate Lactonizing	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0050023,GO:0071704,GO:1901575	4.2.1.6,4.2.1.68	ko:K01684,ko:K18334	ko00051,ko00052,ko01100,ko01120,map00051,map00052,map01100,map01120	M00552	R03033,R03688	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS2_k127_3582010_2	1123277.KB893195_gene5526	1.459e-98	327.0	COG1028@1|root,COG1028@2|Bacteria,4NGYN@976|Bacteroidetes,47MXU@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS2_k127_3582010_0	313596.RB2501_00991	4.523e-145	464.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1HYU7@117743|Flavobacteriia	976|Bacteroidetes	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS2_k127_3582010_1	485917.Phep_2314	5.193e-102	340.0	COG3386@1|root,COG3386@2|Bacteria,4NMJX@976|Bacteroidetes,1IS6S@117747|Sphingobacteriia	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
CMS2_k127_3599339_6	1121012.AUKX01000048_gene1949	2.459e-08	60.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase,Zn_ribbon_recom
CMS2_k127_3599339_2	313596.RB2501_12994	0.0	1060.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
CMS2_k127_3599339_3	313596.RB2501_12989	2.432e-208	652.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HX7B@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS2_k127_3599339_5	313596.RB2501_12984	2.887e-105	347.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia	976|Bacteroidetes	M	Hydrolase Nlp P60	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
CMS2_k127_3599339_4	313596.RB2501_12979	5.307e-187	592.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1HX8F@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
CMS2_k127_3599339_0	313596.RB2501_12974	0.0	1500.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS2_k127_3599339_1	616991.JPOO01000001_gene3885	0.0	1453.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia,23GWG@178469|Arenibacter	976|Bacteroidetes	O	C-terminal, D2-small domain, of ClpB protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS2_k127_3601076_7	313596.RB2501_01730	2.368e-24	107.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1HX8A@117743|Flavobacteriia	976|Bacteroidetes	S	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
CMS2_k127_3601076_5	313596.RB2501_01740	1.158e-43	163.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS2_k127_3601076_2	313596.RB2501_01745	3.198e-115	377.0	COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,1HXZW@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS2_k127_3601076_1	313596.RB2501_01750	5.302e-192	607.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS2_k127_3601076_4	1121875.KB907547_gene3395	1.899e-45	167.0	2AFVV@1|root,315YK@2|Bacteria,4NQ4S@976|Bacteroidetes,1I2VI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3601076_0	313596.RB2501_06320	2.501e-259	807.0	COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,1I137@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_3601076_6	402612.FP0766	3.396e-37	143.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia,2NUSI@237|Flavobacterium	976|Bacteroidetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
CMS2_k127_3607176_6	313596.RB2501_05385	3.024e-24	106.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,1HZDQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3607176_2	313596.RB2501_05380	8.031e-78	267.0	28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes,1I0C7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3607176_4	1122134.KB893650_gene1300	3.472e-43	168.0	COG0454@1|root,COG0456@2|Bacteria,1RJDS@1224|Proteobacteria,1SAWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS2_k127_3607176_1	313596.RB2501_05365	1.035e-122	403.0	COG2010@1|root,COG2010@2|Bacteria,4PMA9@976|Bacteroidetes,1HXRI@117743|Flavobacteriia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_3607176_0	313596.RB2501_05360	0.0	1676.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_3607176_3	313596.RB2501_05355	1.304e-51	190.0	2E47V@1|root,32Z3R@2|Bacteria,4NX7P@976|Bacteroidetes,1I616@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3607176_5	760192.Halhy_3002	4.276e-37	149.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1IP1V@117747|Sphingobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS2_k127_3607176_7	395493.BegalDRAFT_2096	1.325e-19	104.0	COG0457@1|root,COG0457@2|Bacteria,1MWRF@1224|Proteobacteria,1S182@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Pfam Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7,TPR_8
CMS2_k127_3621754_6	313596.RB2501_15194	6.16e-40	149.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1HWK9@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS2_k127_3621754_1	313596.RB2501_15199	3.913e-281	866.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CMS2_k127_3621754_2	313596.RB2501_15204	6.389e-187	587.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS2_k127_3621754_3	313596.RB2501_15209	1.299e-183	583.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
CMS2_k127_3621754_0	313596.RB2501_15214	1.506e-296	914.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1HY11@117743|Flavobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
CMS2_k127_3621754_5	313596.RB2501_15219	2.254e-46	168.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11
CMS2_k127_3621754_4	313596.RB2501_15224	1.12e-48	177.0	COG2932@1|root,COG2932@2|Bacteria,4NRR6@976|Bacteroidetes,1I4RY@117743|Flavobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3621754_7	1121875.KB907548_gene1377	4.356e-10	64.0	29IQ8@1|root,33161@2|Bacteria,4NVDJ@976|Bacteroidetes,1I66B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3629585_1	313596.RB2501_13574	1.322e-99	331.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia	976|Bacteroidetes	N	gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS2_k127_3629585_0	313596.RB2501_13569	2.505e-168	538.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia	976|Bacteroidetes	N	Gliding motility protein GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS2_k127_3632115_3	1004149.AFOE01000020_gene3123	4.281e-17	94.0	COG1404@1|root,COG4386@1|root,COG1404@2|Bacteria,COG4386@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	bhp	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	B_lectin,CHU_C,Calx-beta
CMS2_k127_3632115_2	313596.RB2501_09585	2.22e-62	219.0	2C59T@1|root,305DH@2|Bacteria,4NNXD@976|Bacteroidetes,1I259@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3632115_1	313596.RB2501_09580	3.126e-83	281.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1IJPJ@117743|Flavobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS2_k127_3632115_0	1121875.KB907549_gene1763	2.257e-103	353.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
CMS2_k127_3634634_4	616991.JPOO01000001_gene4190	9.951e-82	277.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS2_k127_3634634_3	1538644.KO02_19140	3.712e-181	589.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1IP14@117747|Sphingobacteriia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
CMS2_k127_3634634_2	313596.RB2501_04560	1.121e-248	770.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS2_k127_3634634_0	313596.RB2501_04555	0.0	1781.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1HX66@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
CMS2_k127_3634634_1	313596.RB2501_04540	4.008e-264	816.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1HXW8@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of D-xylose to D-xylulose	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
CMS2_k127_3634634_5	313596.RB2501_04535	2.323e-79	268.0	COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,1HXH0@117743|Flavobacteriia	976|Bacteroidetes	G	Carbohydrate kinase	xylB_2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS2_k127_3635688_4	313596.RB2501_11112	3.718e-63	217.0	COG1522@1|root,COG1522@2|Bacteria,4NNMR@976|Bacteroidetes,1I21F@117743|Flavobacteriia	976|Bacteroidetes	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS2_k127_3635688_5	313596.RB2501_11107	4.68e-59	207.0	2A5FE@1|root,30U5C@2|Bacteria,4NQNR@976|Bacteroidetes,1IJ1J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3635688_0	313596.RB2501_11102	0.0	1871.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS2_k127_3635688_6	313596.RB2501_11067	5.123e-16	80.0	2E9FR@1|root,333P1@2|Bacteria,4NUSM@976|Bacteroidetes,1I5QZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3635688_2	313596.RB2501_11062	9.026e-120	391.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1HX31@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS2_k127_3635688_1	313596.RB2501_11057	9.531e-200	627.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1HYAP@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS2_k127_3635688_3	313596.RB2501_11047	1.234e-73	250.0	COG2146@1|root,COG2146@2|Bacteria,4PMAK@976|Bacteroidetes,1I2JM@117743|Flavobacteriia	976|Bacteroidetes	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS2_k127_3635688_7	471854.Dfer_4180	5.215e-07	51.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,47JG0@768503|Cytophagia	976|Bacteroidetes	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS2_k127_3650494_0	313596.RB2501_06350	0.0	1476.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
CMS2_k127_3650494_2	391603.FBALC1_16297	2.554e-19	91.0	2DNGD@1|root,32XCZ@2|Bacteria,4NSM2@976|Bacteroidetes,1I4Q7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3650494_1	313596.RB2501_06345	4.382e-238	747.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1HZDM@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS2_k127_3700716_2	1408433.JHXV01000027_gene3751	2.574e-09	58.0	2E3AK@1|root,32YA3@2|Bacteria,4NUYM@976|Bacteroidetes,1I52E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3700716_0	313596.RB2501_14084	1.308e-227	716.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS2_k127_3700716_1	313596.RB2501_14094	4.843e-182	572.0	COG0524@1|root,COG0524@2|Bacteria,4NJIK@976|Bacteroidetes,1I00V@117743|Flavobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS2_k127_3703891_5	313596.RB2501_16089	9.589e-47	181.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1HY82@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
CMS2_k127_3703891_2	313596.RB2501_16084	4.714e-102	341.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,1HWX9@117743|Flavobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_3703891_6	932213.SPM24T3_20664	2.141e-20	99.0	COG1011@1|root,COG1011@2|Bacteria,1PGNF@1224|Proteobacteria,1RRDC@1236|Gammaproteobacteria,3ZZX7@613|Serratia	1236|Gammaproteobacteria	S	Haloacid dehalogenase-like hydrolase	yihX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050308	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS2_k127_3703891_1	313596.RB2501_16074	1.946e-149	484.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1HX8D@117743|Flavobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS2_k127_3703891_4	313596.RB2501_16069	5.189e-71	243.0	COG0454@1|root,COG0456@2|Bacteria,4NNG9@976|Bacteroidetes,1I23X@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	yjgM	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS2_k127_3703891_3	313596.RB2501_16064	1.196e-100	341.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
CMS2_k127_3703891_0	313596.RB2501_16059	1.04e-256	797.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS2_k127_3707045_3	1121012.AUKX01000012_gene2263	2.533e-173	550.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia,23GQ5@178469|Arenibacter	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_3707045_2	313596.RB2501_15319	1.19e-204	641.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1HWMK@117743|Flavobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS2_k127_3707045_0	313596.RB2501_15314	0.0	1121.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS2_k127_3707045_1	313596.RB2501_15309	1.521e-228	710.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
CMS2_k127_3707275_0	313596.RB2501_13744	0.0	1246.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS2_k127_3707275_2	313596.RB2501_13749	5.984e-63	221.0	COG0668@1|root,COG0668@2|Bacteria,4NMMB@976|Bacteroidetes,1I2BV@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS2_k127_3707275_1	313596.RB2501_13759	4.473e-69	239.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1I17Y@117743|Flavobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS2_k127_3707275_3	313596.RB2501_13764	2.027e-20	91.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
CMS2_k127_3717924_3	1250232.JQNJ01000001_gene1020	3.718e-122	400.0	COG0277@1|root,COG0277@2|Bacteria,4NGC5@976|Bacteroidetes,1I144@117743|Flavobacteriia	976|Bacteroidetes	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
CMS2_k127_3717924_5	643867.Ftrac_1111	1.683e-35	137.0	COG2350@1|root,COG2350@2|Bacteria,4NVYH@976|Bacteroidetes,47SH9@768503|Cytophagia	976|Bacteroidetes	S	PFAM YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
CMS2_k127_3717924_0	1131812.JQMS01000001_gene40	2.754e-278	879.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
CMS2_k127_3717924_1	313596.RB2501_01760	1.799e-205	646.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,1I0HW@117743|Flavobacteriia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS2_k127_3717924_4	1396141.BATP01000058_gene2018	8.276e-58	210.0	COG5507@1|root,COG5507@2|Bacteria,46UZW@74201|Verrucomicrobia,2IUBU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
CMS2_k127_3717924_6	1237149.C900_04318	4.909e-20	100.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes,47SE5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CMS2_k127_3717924_2	1313301.AUGC01000005_gene263	6.858e-195	616.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes	976|Bacteroidetes	O	Collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CMS2_k127_3745735_0	313596.RB2501_06585	0.0	1047.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1HXND@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
CMS2_k127_3745735_12	313603.FB2170_05650	1.182e-62	220.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia,2PHCT@252356|Maribacter	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS2_k127_3745735_18	313603.FB2170_05645	3.372e-23	100.0	2DPF8@1|root,331U0@2|Bacteria,4NX8B@976|Bacteroidetes,1I64D@117743|Flavobacteriia	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
CMS2_k127_3745735_16	313596.RB2501_06570	9.883e-41	156.0	2BY49@1|root,32U9Y@2|Bacteria,4NSER@976|Bacteroidetes,1I4B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3745735_4	313596.RB2501_06565	6.946e-195	617.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS2_k127_3745735_17	313596.RB2501_06560	9.055e-29	115.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS2_k127_3745735_10	313596.RB2501_06555	8.364e-76	257.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS2_k127_3745735_13	313596.RB2501_06550	1.054e-57	205.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1I28E@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS2_k127_3745735_1	313596.RB2501_06545	4.75e-313	962.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS2_k127_3745735_5	313596.RB2501_06540	1.205e-143	460.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS2_k127_3745735_15	313596.RB2501_06535	7.569e-41	162.0	2E7B3@1|root,331UH@2|Bacteria,4NUQ4@976|Bacteroidetes,1I5N0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3745735_2	313596.RB2501_06530	1.523e-243	762.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CMS2_k127_3745735_11	313596.RB2501_06525	6.661e-68	233.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS2_k127_3745735_9	313596.RB2501_06520	1.373e-87	300.0	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	-	-	-	ko:K08309,ko:K11935,ko:K20543	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01011,ko02000	1.B.55.3	GH23	-	BCSC_C,TPR_12,TPR_16,TPR_19,TPR_6,TPR_8
CMS2_k127_3745735_7	313596.RB2501_06515	4.132e-106	350.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1HX5K@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
CMS2_k127_3745735_3	313596.RB2501_06510	4.366e-198	623.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1HWW3@117743|Flavobacteriia	976|Bacteroidetes	D	peptidase M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_3745735_6	313596.RB2501_06505	4.771e-135	434.0	COG0656@1|root,COG0656@2|Bacteria,4NFTA@976|Bacteroidetes,1HXQP@117743|Flavobacteriia	976|Bacteroidetes	S	Reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_3745735_8	1121875.KB907551_gene1132	1.79e-89	297.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia	976|Bacteroidetes	I	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS2_k127_3745735_14	313596.RB2501_06495	7.993e-55	195.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_3767131_2	1121875.KB907552_gene277	6.784e-48	172.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1HXIP@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS2_k127_3767131_1	1121875.KB907552_gene278	7.136e-65	227.0	28RUM@1|root,2ZE6Z@2|Bacteria,4NMVD@976|Bacteroidetes,1I1P3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3767131_0	313596.RB2501_03340	1.038e-263	815.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1IJBB@117743|Flavobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS2_k127_3775628_2	313596.RB2501_03850	5.957e-144	458.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia	976|Bacteroidetes	K	RNA polymerase sigma54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS2_k127_3775628_7	313596.RB2501_03855	2.556e-88	297.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,1I1C6@117743|Flavobacteriia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3775628_6	313596.RB2501_03860	1.926e-92	308.0	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS2_k127_3775628_8	313596.RB2501_03865	4.419e-87	289.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,1I1CY@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS2_k127_3775628_5	1121875.KB907550_gene871	1.674e-109	356.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1HYCZ@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS2_k127_3775628_11	313596.RB2501_03875	1.453e-45	169.0	2AT2U@1|root,31IIU@2|Bacteria,4NS9K@976|Bacteroidetes,1I3WD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3775628_3	1121875.KB907550_gene869	2.925e-136	437.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_3775628_1	313596.RB2501_03885	7.517e-165	526.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia	976|Bacteroidetes	EJ	GlutRNAGln amidotransferase subunit D	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS2_k127_3775628_4	313596.RB2501_03890	3.362e-113	370.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1HXDX@117743|Flavobacteriia	976|Bacteroidetes	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS2_k127_3775628_10	313596.RB2501_03895	2.334e-51	185.0	COG3577@1|root,COG3577@2|Bacteria,4NNI0@976|Bacteroidetes,1I1Z6@117743|Flavobacteriia	976|Bacteroidetes	S	protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
CMS2_k127_3775628_0	1121875.KB907550_gene865	7.621e-196	618.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_3775628_9	313596.RB2501_03905	3.121e-65	224.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS2_k127_3794931_1	313596.RB2501_08325	5.306e-123	396.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia	976|Bacteroidetes	S	zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS2_k127_3794931_2	313596.RB2501_08330	9.526e-92	302.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1HYHU@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS2_k127_3794931_0	313596.RB2501_08335	1.135e-128	413.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS2_k127_3802911_6	1121957.ATVL01000008_gene4224	8.483e-13	74.0	2DTRJ@1|root,33MDI@2|Bacteria,4NVIB@976|Bacteroidetes,47RU9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3802911_2	1249997.JHZW01000002_gene1551	3.414e-106	351.0	COG4221@1|root,COG4221@2|Bacteria,4PKIR@976|Bacteroidetes,1IJAA@117743|Flavobacteriia,2PICC@252356|Maribacter	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_3802911_1	313596.RB2501_10712	2.619e-118	387.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1I084@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CMS2_k127_3802911_0	313596.RB2501_10652	1.01e-185	589.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1HYKQ@117743|Flavobacteriia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
CMS2_k127_3802911_4	313596.RB2501_10642	4.535e-91	301.0	COG4502@1|root,COG4502@2|Bacteria,4NQDT@976|Bacteroidetes,1I1FP@117743|Flavobacteriia	976|Bacteroidetes	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
CMS2_k127_3802911_3	1296416.JACB01000004_gene1153	3.106e-101	338.0	arCOG10603@1|root,32SV6@2|Bacteria,4NJM3@976|Bacteroidetes,1HXZQ@117743|Flavobacteriia,2YKMX@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_381301_0	313596.RB2501_00426	7.904e-295	909.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1HXCS@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_381301_1	1250232.JQNJ01000001_gene3760	3.589e-206	646.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWRC@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS2_k127_381301_2	313596.RB2501_00411	1.267e-180	567.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS2_k127_3816004_3	313596.RB2501_06585	3.639e-78	265.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1HXND@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
CMS2_k127_3816004_2	313603.FB2170_05660	3.964e-119	385.0	COG1131@1|root,COG1131@2|Bacteria,4NDV7@976|Bacteroidetes,1HWXK@117743|Flavobacteriia,2PGCQ@252356|Maribacter	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_3816004_0	313596.RB2501_06595	5.547e-253	788.0	28ID4@1|root,2Z8FC@2|Bacteria,4NFYZ@976|Bacteroidetes,1HXPK@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3816004_1	313596.RB2501_06600	5.539e-121	396.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia	976|Bacteroidetes	C	Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS2_k127_383100_1	1250232.JQNJ01000001_gene2402	1.663e-188	591.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,1HY4I@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS2_k127_383100_0	313596.RB2501_01905	0.0	1206.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1HX05@117743|Flavobacteriia	976|Bacteroidetes	E	Aminoacyl peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_3861411_4	388413.ALPR1_08893	3.792e-74	251.0	COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia	976|Bacteroidetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS2_k127_3861411_5	1443665.JACA01000053_gene3321	2.237e-43	163.0	COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,1I41T@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS2_k127_3861411_0	313596.RB2501_01775	0.0	1318.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS2_k127_3861411_3	313596.RB2501_01780	1.373e-86	288.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1I19U@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS2_k127_3861411_1	313596.RB2501_01785	4.516e-245	763.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS2_k127_3861411_2	313596.RB2501_01790	3.058e-173	549.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
CMS2_k127_3879035_1	760192.Halhy_0911	9.498e-66	236.0	COG0657@1|root,COG2382@1|root,COG0657@2|Bacteria,COG2382@2|Bacteria,4PKKH@976|Bacteroidetes,1J0WF@117747|Sphingobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
CMS2_k127_3879035_0	313596.RB2501_00876	5.622e-206	646.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,1HY8Y@117743|Flavobacteriia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase concanavalin-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS2_k127_3891815_5	313596.RB2501_00711	0.0001924	46.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1HY7E@117743|Flavobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS2_k127_3891815_4	313596.RB2501_00706	1.572e-25	106.0	2E59P@1|root,3301Z@2|Bacteria,4NUUS@976|Bacteroidetes,1I52U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3891815_0	313596.RB2501_00701	9.246e-167	527.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1HXGU@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS2_k127_3891815_2	313596.RB2501_00686	1.308e-54	197.0	COG0454@1|root,COG0456@2|Bacteria,4NHRI@976|Bacteroidetes,1HZCX@117743|Flavobacteriia	976|Bacteroidetes	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,HTH_27,MarR,MarR_2
CMS2_k127_3891815_1	1121875.KB907546_gene2757	7.531e-110	364.0	COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes,1HYV9@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_3891815_3	313596.RB2501_00681	1.264e-44	164.0	2ETFQ@1|root,33KZK@2|Bacteria,4NXGS@976|Bacteroidetes,1I6K5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3892931_0	1121011.AUCB01000017_gene3856	2.885e-301	926.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia,23GZM@178469|Arenibacter	976|Bacteroidetes	O	Uncharacterized protein family (UPF0051)	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS2_k127_3892931_2	313596.RB2501_05910	8.644e-57	199.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS2_k127_3892931_1	313596.RB2501_05895	9.613e-177	561.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1HWNB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS2_k127_3903977_3	1250232.JQNJ01000001_gene1278	2.226e-82	274.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1HXRK@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
CMS2_k127_3903977_0	313596.RB2501_13299	5.866e-188	588.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1HXPZ@117743|Flavobacteriia	976|Bacteroidetes	EH	sulfate adenylyltransferase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS2_k127_3903977_2	313596.RB2501_13304	2.841e-89	298.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,1I20M@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS2_k127_3903977_4	313596.RB2501_13309	1.974e-69	237.0	COG3205@1|root,COG3205@2|Bacteria,4NV6E@976|Bacteroidetes,1I208@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
CMS2_k127_3903977_1	313596.RB2501_13314	1.15e-113	374.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,1HXAV@117743|Flavobacteriia	976|Bacteroidetes	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS2_k127_3933075_2	313596.RB2501_13784	1.12e-111	364.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1IJ8Q@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS2_k127_3933075_1	313596.RB2501_13789	1.509e-130	419.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS2_k127_3933075_0	313596.RB2501_13794	1.399e-296	926.0	COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_10,TPR_12,TPR_7,TPR_8
CMS2_k127_3944417_9	313596.RB2501_05610	6.479e-24	101.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia	976|Bacteroidetes	P	Chloride channel protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS2_k127_3944417_1	313596.RB2501_05605	0.0	1009.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS2_k127_3944417_0	313596.RB2501_05600	0.0	1877.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS2_k127_3944417_3	313596.RB2501_05595	5.296e-172	548.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS2_k127_3944417_2	313596.RB2501_05590	2.501e-202	637.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_3944417_7	143224.JQMD01000002_gene3383	5.626e-83	279.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1I0I9@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_3944417_5	313596.RB2501_05570	5.628e-155	500.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS2_k127_3944417_6	1121875.KB907553_gene55	2.143e-120	398.0	COG0644@1|root,COG0644@2|Bacteria,4NDTU@976|Bacteroidetes,1HYHZ@117743|Flavobacteriia	976|Bacteroidetes	C	lycopene cyclase	crtY	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
CMS2_k127_3944417_8	313596.RB2501_05545	2.672e-71	244.0	COG2318@1|root,COG2318@2|Bacteria,4NS3A@976|Bacteroidetes,1I2YI@117743|Flavobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CMS2_k127_3944417_4	1250232.JQNJ01000001_gene1509	1.291e-165	530.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_3960811_4	313596.RB2501_14424	5.953e-38	142.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,1HZAW@117743|Flavobacteriia	976|Bacteroidetes	E	Acetolactate synthase small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
CMS2_k127_3960811_0	313596.RB2501_14419	4.4e-323	994.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1HXF9@117743|Flavobacteriia	976|Bacteroidetes	E	acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS2_k127_3960811_1	313596.RB2501_14414	1.304e-317	977.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS2_k127_3960811_2	313596.RB2501_14409	2.431e-109	360.0	COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,1HXTB@117743|Flavobacteriia	976|Bacteroidetes	E	Allophanate hydrolase subunit 2	-	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
CMS2_k127_3960811_3	1250232.JQNJ01000001_gene3503	1.158e-57	203.0	COG2049@1|root,COG2049@2|Bacteria,4NMNT@976|Bacteroidetes,1I1C1@117743|Flavobacteriia	976|Bacteroidetes	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
CMS2_k127_3969287_0	313596.RB2501_12032	3.7e-176	555.0	COG1082@1|root,COG1082@2|Bacteria,4NEUS@976|Bacteroidetes,1I65S@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	iolI	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_3969287_1	313596.RB2501_04460	1.185e-26	111.0	COG5544@1|root,COG5544@2|Bacteria,4NWYR@976|Bacteroidetes,1I596@117743|Flavobacteriia	976|Bacteroidetes	S	Lipoprotein	-	-	-	ko:K05811	-	-	-	-	ko00000	-	-	-	-
CMS2_k127_3992498_2	886377.Murru_0596	2.925e-163	522.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1HZCR@117743|Flavobacteriia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS2_k127_3992498_1	1250232.JQNJ01000001_gene506	1.027e-307	947.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HZ5E@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_3992498_3	616991.JPOO01000003_gene2301	1.257e-75	259.0	COG0558@1|root,COG0558@2|Bacteria,4NHGH@976|Bacteroidetes,1HZ13@117743|Flavobacteriia	976|Bacteroidetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS2_k127_3992498_4	313596.RB2501_07180	1.431e-61	221.0	2E3AK@1|root,320TI@2|Bacteria,4NRX2@976|Bacteroidetes,1I3SJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3992498_0	313596.RB2501_09500	7.466e-313	962.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HX4R@117743|Flavobacteriia	976|Bacteroidetes	P	arylsulfatase a	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS2_k127_4050108_2	1121875.KB907547_gene3475	1.554e-20	95.0	COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,1I5M1@117743|Flavobacteriia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
CMS2_k127_4050108_0	313596.RB2501_00561	1.287e-207	652.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_4050108_1	1122176.KB903565_gene3264	3.215e-63	220.0	28PQP@1|root,2ZCCM@2|Bacteria,4NSQ2@976|Bacteroidetes,1IZYZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
CMS2_k127_4058575_1	1408473.JHXO01000007_gene826	9.313e-50	198.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
CMS2_k127_4058575_0	313596.RB2501_14364	3.533e-174	564.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M_N
CMS2_k127_4058575_2	886377.Murru_0465	1.59e-12	67.0	28I8D@1|root,2Z80E@2|Bacteria,4NG48@976|Bacteroidetes,1I0U8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
CMS2_k127_4059022_1	313596.RB2501_11287	3.917e-62	216.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1I2S7@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
CMS2_k127_4059022_0	313596.RB2501_11282	1.883e-190	599.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia	976|Bacteroidetes	E	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_4071189_3	1250232.JQNJ01000001_gene1606	1.393e-37	141.0	COG2041@1|root,COG2041@2|Bacteria,4NEIQ@976|Bacteroidetes,1I0IA@117743|Flavobacteriia	976|Bacteroidetes	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS2_k127_4071189_2	313596.RB2501_07260	4.21e-48	180.0	2E0TJ@1|root,32WB7@2|Bacteria,4NTAN@976|Bacteroidetes,1I25N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4071189_0	313603.FB2170_14978	3.698e-165	523.0	COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,1HWTG@117743|Flavobacteriia,2PGKD@252356|Maribacter	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_4071189_1	313596.RB2501_07250	8.905e-50	184.0	COG0607@1|root,COG0607@2|Bacteria,4NQ61@976|Bacteroidetes,1I2V7@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_4071189_5	1249975.JQLP01000001_gene3465	1.245e-09	67.0	COG1794@1|root,COG1794@2|Bacteria,4NI4F@976|Bacteroidetes,1IIB7@117743|Flavobacteriia,2P7EK@244698|Gillisia	976|Bacteroidetes	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
CMS2_k127_4071189_4	1250232.JQNJ01000001_gene1603	1.324e-25	109.0	COG2010@1|root,COG2010@2|Bacteria,4NIRV@976|Bacteroidetes,1HX5S@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF3365
CMS2_k127_4108487_1	313596.RB2501_05205	5.562e-82	274.0	COG2524@1|root,COG2524@2|Bacteria,4PKJK@976|Bacteroidetes,1I18Z@117743|Flavobacteriia	976|Bacteroidetes	K	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS2_k127_4108487_2	143224.JQMD01000002_gene3458	1.374e-31	126.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
CMS2_k127_4108487_0	313596.RB2501_05195	4.255e-102	336.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_4124778_2	313596.RB2501_03110	6.633e-299	922.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1IMSC@117743|Flavobacteriia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS2_k127_4124778_5	313596.RB2501_03110	2.687e-171	545.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1IMSC@117743|Flavobacteriia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS2_k127_4124778_8	1249997.JHZW01000003_gene3852	2.752e-107	350.0	COG0175@1|root,COG0175@2|Bacteria,4PH3N@976|Bacteroidetes,1HWTX@117743|Flavobacteriia,2PG8D@252356|Maribacter	976|Bacteroidetes	EH	Phosphoadenosine phosphosulfate reductase family	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS2_k127_4124778_9	313596.RB2501_03140	1.026e-69	240.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1I1Z9@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS2_k127_4124778_4	313596.RB2501_03145	3.215e-225	701.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1IJ8Q@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS2_k127_4124778_0	313596.RB2501_03150	0.0	1842.0	COG0460@1|root,COG0527@1|root,COG2021@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,COG2021@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Abhydrolase_1,Homoserine_dh,NAD_binding_3
CMS2_k127_4124778_3	313596.RB2501_03155	8.114e-238	738.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1HX18@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS2_k127_4124778_7	313596.RB2501_03160	1.062e-133	430.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
CMS2_k127_4124778_6	313596.RB2501_03165	2.687e-158	504.0	COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,1HX0X@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
CMS2_k127_4124778_1	313596.RB2501_03175	7.651e-304	938.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS2_k127_4159299_0	313596.RB2501_07780	5.975e-268	827.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_4159299_1	313596.RB2501_07775	1.894e-195	615.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1HXPE@117743|Flavobacteriia	976|Bacteroidetes	E	cystathionine	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CMS2_k127_4159299_5	313596.RB2501_07770	1.054e-84	287.0	28JBH@1|root,2Z967@2|Bacteria,4NNHF@976|Bacteroidetes,1HYEA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
CMS2_k127_4159299_7	313596.RB2501_07765	3.417e-42	158.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1I450@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS2_k127_4159299_3	313596.RB2501_07760	2.042e-136	439.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_4159299_6	313596.RB2501_07755	2.648e-60	212.0	COG0824@1|root,COG0824@2|Bacteria,4NS45@976|Bacteroidetes,1I1HB@117743|Flavobacteriia	976|Bacteroidetes	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS2_k127_4159299_2	313596.RB2501_07750	6.435e-166	528.0	COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1HY76@117743|Flavobacteriia	976|Bacteroidetes	S	related to 2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS2_k127_4159299_4	313596.RB2501_07745	1.649e-108	356.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,1HY3H@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
CMS2_k127_41948_0	313596.RB2501_10422	0.0	1483.0	COG0457@1|root,COG1729@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3903@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CMS2_k127_41948_1	313596.RB2501_10427	2.035e-272	848.0	COG1629@1|root,COG4771@2|Bacteria,4PKB3@976|Bacteroidetes,1IJ66@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
CMS2_k127_41948_2	313596.RB2501_10432	6.038e-50	183.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS2_k127_4224667_2	313596.RB2501_11377	1.453e-230	719.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1HYKT@117743|Flavobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS2_k127_4224667_4	313596.RB2501_11372	8.337e-102	335.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,1I23T@117743|Flavobacteriia	976|Bacteroidetes	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
CMS2_k127_4224667_1	313596.RB2501_11367	3.302e-238	739.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1HXB7@117743|Flavobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS2_k127_4224667_5	1249997.JHZW01000001_gene4002	4.355e-81	272.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia,2PGYJ@252356|Maribacter	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
CMS2_k127_4224667_3	487796.Flav2ADRAFT_1402	5.41e-190	607.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1HYQE@117743|Flavobacteriia	976|Bacteroidetes	G	L-sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
CMS2_k127_4224667_0	313596.RB2501_11357	1.157e-269	833.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1HWYC@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS2_k127_4229697_1	313596.RB2501_07785	2.632e-90	304.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1I1E3@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS2_k127_4229697_0	313596.RB2501_07800	0.0	1947.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CMS2_k127_4252106_2	313596.RB2501_06830	5.685e-162	516.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS2_k127_4252106_1	313596.RB2501_06835	9.354e-169	533.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS2_k127_4252106_0	313596.RB2501_06855	2.397e-260	806.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1HXAH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS2_k127_4263262_5	1122176.KB903537_gene1670	4.436e-31	129.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1IWR2@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
CMS2_k127_4263262_1	313596.RB2501_10065	1.011e-85	286.0	COG1595@1|root,COG1595@2|Bacteria,4NMCX@976|Bacteroidetes,1I1EN@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_4263262_0	313596.RB2501_10070	5.646e-269	839.0	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4263262_2	67315.JOBD01000014_gene6715	3.042e-51	184.0	COG0346@1|root,COG0346@2|Bacteria,2IHR7@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_4263262_3	313598.MED152_16397	4.203e-43	162.0	COG0454@1|root,COG0456@2|Bacteria,4NSH4@976|Bacteroidetes,1I419@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
CMS2_k127_4263262_4	1123248.KB893319_gene4016	3.355e-31	126.0	COG2764@1|root,COG2764@2|Bacteria,4P63R@976|Bacteroidetes	976|Bacteroidetes	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_429033_7	351160.RCIX1712	3.294e-10	63.0	COG5646@1|root,arCOG09457@2157|Archaea,2Y6W7@28890|Euryarchaeota,2NAY6@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS2_k127_429033_3	313596.RB2501_11432	9.449e-195	611.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1HX5R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_429033_4	313596.RB2501_11427	7.248e-154	497.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1HY13@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_429033_5	1250232.JQNJ01000001_gene235	9.001e-136	436.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,1HYGY@117743|Flavobacteriia	976|Bacteroidetes	S	Excinuclease ABC subunit B	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
CMS2_k127_429033_1	313596.RB2501_11417	1.059e-245	771.0	COG3391@1|root,COG5492@1|root,COG3391@2|Bacteria,COG5492@2|Bacteria,4NJ74@976|Bacteroidetes,1HY1J@117743|Flavobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS2_k127_429033_2	313596.RB2501_11412	6.652e-203	644.0	COG3391@1|root,COG3391@2|Bacteria,4P1V0@976|Bacteroidetes,1I7XM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS2_k127_429033_0	313596.RB2501_11402	0.0	1189.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS2_k127_429033_6	313596.RB2501_11397	7.718e-37	139.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS2_k127_4293702_2	313596.RB2501_04170	1.193e-257	799.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS2_k127_4293702_3	1121875.KB907550_gene822	8.56e-136	438.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS2_k127_4293702_5	886377.Murru_1778	8.478e-19	87.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
CMS2_k127_4293702_0	1004149.AFOE01000027_gene1843	0.0	1361.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
CMS2_k127_4293702_6	1250005.PHEL85_1483	9.124e-17	82.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia,3VWUI@52959|Polaribacter	976|Bacteroidetes	P	Cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS2_k127_4293702_1	313596.RB2501_04145	0.0	1172.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1HXJI@117743|Flavobacteriia	976|Bacteroidetes	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CMS2_k127_4293702_4	313596.RB2501_04140	6.15e-106	346.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_4351427_4	886377.Murru_0299	5.375e-20	90.0	2DMKZ@1|root,32SAQ@2|Bacteria,4NS7K@976|Bacteroidetes,1I49R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4351427_2	313596.RB2501_11757	5.226e-50	184.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1I1ZP@117743|Flavobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
CMS2_k127_4351427_1	313596.RB2501_11762	5.758e-57	203.0	2AFY2@1|root,3161T@2|Bacteria,4NRC0@976|Bacteroidetes,1I33T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4351427_0	313596.RB2501_11767	2.408e-197	619.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1HXF8@117743|Flavobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS2_k127_4351427_5	394221.Mmar10_0063	4.151e-12	68.0	COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,2UGFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
CMS2_k127_4355934_2	313596.RB2501_08820	1.322e-115	377.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS2_k127_4355934_1	313596.RB2501_08825	7.412e-180	571.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4355934_0	313596.RB2501_08830	1.025e-207	650.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,1HWMR@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS2_k127_4364591_0	313596.RB2501_03615	0.0	2199.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CMS2_k127_4364591_10	1250232.JQNJ01000001_gene2030	7.056e-58	212.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS2_k127_4364591_11	313596.RB2501_03605	1.904e-30	124.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS2_k127_4364591_3	313596.RB2501_03600	2.981e-123	398.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_4364591_2	313596.RB2501_03595	2.302e-157	499.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1HXXM@117743|Flavobacteriia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS2_k127_4364591_7	313596.RB2501_03590	1.289e-85	287.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1I1D8@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS2_k127_4364591_1	313596.RB2501_03585	9.377e-173	546.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS2_k127_4364591_9	313596.RB2501_03580	5.855e-66	226.0	2AVR2@1|root,31MIB@2|Bacteria,4NQKM@976|Bacteroidetes,1I2UX@117743|Flavobacteriia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
CMS2_k127_4364591_6	313596.RB2501_03570	1.399e-91	306.0	29WBK@1|root,30HX5@2|Bacteria,4NMWM@976|Bacteroidetes,1I1KG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4364591_4	313596.RB2501_03565	4.999e-112	366.0	COG1999@1|root,COG1999@2|Bacteria,4NGHC@976|Bacteroidetes,1HXW6@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	ypmQ	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS2_k127_4364591_8	313596.RB2501_03560	1.025e-77	263.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
CMS2_k127_4364591_12	1121011.AUCB01000007_gene1282	1.061e-19	90.0	2E3I4@1|root,32YGK@2|Bacteria,4NUQ9@976|Bacteroidetes,1I53J@117743|Flavobacteriia,23HPH@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4364591_5	313596.RB2501_03550	2.348e-103	338.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_4369119_1	313596.RB2501_15824	4.193e-157	497.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1HXV7@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_4369119_0	313596.RB2501_15829	2.362e-191	607.0	COG1225@1|root,COG1225@2|Bacteria,4NH32@976|Bacteroidetes,1HWQJ@117743|Flavobacteriia	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
CMS2_k127_4369119_2	313596.RB2501_15834	1.458e-129	417.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1HXUY@117743|Flavobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS2_k127_4369119_3	313596.RB2501_15839	3.463e-113	371.0	COG4221@1|root,COG4221@2|Bacteria,4NGKR@976|Bacteroidetes,1HYM0@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	vdlC	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_439396_6	1121875.KB907547_gene3302	8.07e-67	231.0	COG3743@1|root,COG3743@2|Bacteria,4NQAU@976|Bacteroidetes,1I38D@117743|Flavobacteriia	976|Bacteroidetes	S	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_439396_5	313596.RB2501_07675	1.429e-113	370.0	COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,1HWXJ@117743|Flavobacteriia	976|Bacteroidetes	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	pphA	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
CMS2_k127_439396_2	313596.RB2501_07660	9.418e-148	474.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,1HYAW@117743|Flavobacteriia	976|Bacteroidetes	G	Sugar kinases, ribokinase family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS2_k127_439396_0	313596.RB2501_07655	6.367e-284	885.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,4NI8U@976|Bacteroidetes,1HYGV@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
CMS2_k127_439396_1	313596.RB2501_07650	2.245e-189	596.0	COG2865@1|root,COG2865@2|Bacteria,4NEF5@976|Bacteroidetes,1HYUG@117743|Flavobacteriia	976|Bacteroidetes	K	PFAM Divergent AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
CMS2_k127_439396_4	313596.RB2501_07645	8.675e-120	388.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_439396_3	313596.RB2501_07640	1.828e-123	402.0	COG4989@1|root,COG4989@2|Bacteria,4NENV@976|Bacteroidetes,1HY8B@117743|Flavobacteriia	976|Bacteroidetes	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_4405726_0	313596.RB2501_05640	4.248e-229	715.0	COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,1HYIN@117743|Flavobacteriia	976|Bacteroidetes	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS2_k127_4405726_1	1249997.JHZW01000002_gene850	1.994e-177	563.0	COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,1HXMY@117743|Flavobacteriia,2PI6T@252356|Maribacter	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CMS2_k127_4410134_1	1122179.KB890425_gene3420	4.596e-46	171.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS2_k127_4410134_0	1249997.JHZW01000003_gene3137	1.331e-167	536.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia,2PHZ7@252356|Maribacter	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_4427755_4	1121875.KB907549_gene1921	1.008e-61	219.0	COG4461@1|root,COG4461@2|Bacteria,4NIBZ@976|Bacteroidetes,1I0CW@117743|Flavobacteriia	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PliI
CMS2_k127_4427755_0	313596.RB2501_12302	0.0	1028.0	COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes,1HZ27@117743|Flavobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_4427755_1	1121012.AUKX01000056_gene1657	1.45e-181	575.0	COG0667@1|root,COG0667@2|Bacteria,4PI89@976|Bacteroidetes,1IG3Q@117743|Flavobacteriia,23IEN@178469|Arenibacter	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_4427755_3	313596.RB2501_01046	2.069e-69	237.0	COG1917@1|root,COG1917@2|Bacteria,4NNR7@976|Bacteroidetes,1I1YT@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_4427755_2	313596.RB2501_01021	1.436e-95	316.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_4431193_0	313596.RB2501_15544	1.21e-234	728.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1HWW2@117743|Flavobacteriia	976|Bacteroidetes	H	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_4431193_1	313596.RB2501_15549	8.143e-194	608.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1HX09@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_4437406_0	760192.Halhy_2533	5.377e-282	874.0	COG2303@1|root,COG2303@2|Bacteria,4NHJT@976|Bacteroidetes,1IRDW@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS2_k127_4437406_2	1121875.KB907549_gene2065	4.738e-185	587.0	COG2885@1|root,COG2885@2|Bacteria,4NI3U@976|Bacteroidetes,1I04E@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
CMS2_k127_4437406_1	1121875.KB907547_gene3397	2.047e-276	869.0	COG2133@1|root,COG2133@2|Bacteria,4NJ2B@976|Bacteroidetes,1IANY@117743|Flavobacteriia	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4437406_5	1121875.KB907547_gene3473	1.286e-20	94.0	2DFWP@1|root,2ZTGY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4437406_3	391603.FBALC1_13067	1.099e-30	132.0	2E3AK@1|root,32YA3@2|Bacteria,4NUYM@976|Bacteroidetes,1IIAT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4437406_4	1121875.KB907559_gene533	1.051e-26	123.0	2E3AK@1|root,30JD7@2|Bacteria,4NPG4@976|Bacteroidetes,1I2KJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4443082_6	313596.RB2501_09950	8.031e-24	100.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1I17M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS2_k127_4443082_0	313596.RB2501_09955	9.043e-264	815.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS2_k127_4443082_5	745718.JADT01000008_gene3144	1.26e-37	141.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1I3WQ@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS2_k127_4443082_7	867900.Celly_2168	1.456e-15	76.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia,1FAKN@104264|Cellulophaga	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS2_k127_4443082_4	313603.FB2170_02405	5.51e-65	223.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1I1ZW@117743|Flavobacteriia,2PHHC@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein S13/S18	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS2_k127_4443082_3	313596.RB2501_09975	1.011e-74	252.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1I1GI@117743|Flavobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS2_k127_4443082_2	313596.RB2501_09980	7.375e-116	374.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1HWWF@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS2_k127_4443082_1	1121875.KB907546_gene2330	2.181e-170	537.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS2_k127_4456853_3	313596.RB2501_16164	1.014e-46	172.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1HX1G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS2_k127_4456853_0	313596.RB2501_16159	8.778e-230	716.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1HZCP@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_4456853_2	313596.RB2501_16154	1.051e-63	219.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1I1YF@117743|Flavobacteriia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS2_k127_4456853_1	313596.RB2501_16149	2.507e-87	289.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1HXFN@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS2_k127_4466546_0	313596.RB2501_02960	9.058e-194	610.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS2_k127_4466546_2	313596.RB2501_02955	4.699e-106	346.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_4466546_1	313596.RB2501_02950	6.676e-139	451.0	COG0171@1|root,COG0171@2|Bacteria,4NEXG@976|Bacteroidetes,1HYCI@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
CMS2_k127_4466546_3	313596.RB2501_02945	2.158e-67	234.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1HYAM@117743|Flavobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4474576_0	313596.RB2501_04255	0.0	1113.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
CMS2_k127_4474576_4	1121012.AUKX01000020_gene1909	7.365e-56	196.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1I2SS@117743|Flavobacteriia,23HC0@178469|Arenibacter	976|Bacteroidetes	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS2_k127_4474576_1	313596.RB2501_04265	9.464e-165	521.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1HXKI@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS2_k127_4474576_2	344747.PM8797T_10429	1.355e-139	451.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_4474576_3	1449076.JOOE01000004_gene369	3.624e-57	207.0	COG5285@1|root,COG5285@2|Bacteria,1R7DG@1224|Proteobacteria,2TTB2@28211|Alphaproteobacteria,2K7VF@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS2_k127_4500915_5	313596.RB2501_05920	1.139e-101	332.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1HWTU@117743|Flavobacteriia	976|Bacteroidetes	O	Part of SUF system involved in inserting iron-sulfur clusters into proteins	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS2_k127_4500915_0	313596.RB2501_05925	6.491e-252	781.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia	976|Bacteroidetes	O	assembly protein, SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS2_k127_4500915_2	313596.RB2501_05930	5.306e-230	716.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS2_k127_4500915_7	313596.RB2501_05935	2.517e-71	243.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
CMS2_k127_4500915_8	313596.RB2501_05940	3.855e-57	201.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS2_k127_4500915_6	313596.RB2501_05945	2.332e-72	247.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1I1A5@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
CMS2_k127_4500915_3	313596.RB2501_05950	7.899e-159	509.0	28J46@1|root,2Z906@2|Bacteria,4NFYM@976|Bacteroidetes,1HX14@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
CMS2_k127_4500915_1	313596.RB2501_05955	1.322e-231	720.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1HXBZ@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS2_k127_4500915_4	1121875.KB907549_gene1761	1.224e-151	490.0	COG0457@1|root,COG1874@1|root,COG3206@1|root,COG0457@2|Bacteria,COG1874@2|Bacteria,COG3206@2|Bacteria,4NH33@976|Bacteroidetes,1HYMC@117743|Flavobacteriia	976|Bacteroidetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4501405_2	313596.RB2501_10452	8.164e-89	293.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS2_k127_4501405_0	313596.RB2501_10447	0.0	1068.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS2_k127_4501405_3	313596.RB2501_10442	4.744e-77	262.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1I2EF@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CMS2_k127_4501405_1	313596.RB2501_10437	5.04e-238	746.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia	976|Bacteroidetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS2_k127_4501405_4	313596.RB2501_10432	1.556e-53	195.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS2_k127_4505893_0	313596.RB2501_06050	1.223e-240	750.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HWYG@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS2_k127_4505893_1	926569.ANT_29640	1.66e-42	161.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS2_k127_4522655_1	1379270.AUXF01000007_gene964	1.485e-214	680.0	COG0308@1|root,COG0308@2|Bacteria,1ZU50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS2_k127_4522655_0	1379270.AUXF01000007_gene963	1.042e-215	680.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS2_k127_4522655_2	1227488.C477_10013	2.744e-18	89.0	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,23WU7@183963|Halobacteria	183963|Halobacteria	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS2_k127_4535465_4	1121012.AUKX01000032_gene673	2.02e-58	204.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1HWYJ@117743|Flavobacteriia,23GP0@178469|Arenibacter	976|Bacteroidetes	J	Elongation factor TS	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS2_k127_4535465_1	1250232.JQNJ01000001_gene1972	1.909e-176	559.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1HWUX@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS2_k127_4535465_3	1392498.JQLH01000001_gene684	6.575e-64	220.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1I21V@117743|Flavobacteriia,2PHEM@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein S9/S16	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS2_k127_4535465_2	313596.RB2501_03805	4.201e-80	268.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1I170@117743|Flavobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS2_k127_4535465_0	313596.RB2501_03800	0.0	1464.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_4535465_5	1296415.JACC01000007_gene2475	3.148e-39	147.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia,2YHNB@290174|Aquimarina	976|Bacteroidetes	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS2_k127_4555948_1	313596.RB2501_03410	4.104e-14	72.0	2EA78@1|root,334BX@2|Bacteria,4NVC4@976|Bacteroidetes,1I51G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4555948_0	313596.RB2501_03415	2.381e-193	613.0	COG2885@1|root,COG2885@2|Bacteria,4NHCS@976|Bacteroidetes,1HZ8F@117743|Flavobacteriia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
CMS2_k127_4556766_1	313596.RB2501_15524	1.444e-44	166.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS2_k127_4556766_0	313596.RB2501_15519	1.837e-139	451.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1HWNP@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS2_k127_4579651_2	313596.RB2501_13609	5.453e-146	467.0	COG2905@1|root,COG2905@2|Bacteria,4NDZ8@976|Bacteroidetes,1HWQU@117743|Flavobacteriia	976|Bacteroidetes	T	signal-transduction protein containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS2_k127_4579651_4	313596.RB2501_13604	2.57e-63	224.0	COG0847@1|root,COG0847@2|Bacteria,4NMUI@976|Bacteroidetes,1I1K8@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS2_k127_4579651_1	313596.RB2501_13594	5.75e-163	517.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1HWM5@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS2_k127_4579651_0	313596.RB2501_13589	1.792e-170	553.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1HWPZ@117743|Flavobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS2_k127_4579651_3	313596.RB2501_13584	4.223e-137	440.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1HX11@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
CMS2_k127_4580494_6	313596.RB2501_02125	2.819e-25	105.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1I50J@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS2_k127_4580494_1	313596.RB2501_02130	1.734e-217	678.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_4580494_3	1250232.JQNJ01000001_gene2365	8.007e-54	200.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1HX4K@117743|Flavobacteriia	976|Bacteroidetes	L	COG1555 DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CMS2_k127_4580494_0	313596.RB2501_02150	0.0	1116.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Biotin_lipoyl,Na_Ala_symp,SprB
CMS2_k127_4580494_2	313596.RB2501_02155	5.65e-166	527.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia	976|Bacteroidetes	P	K transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS2_k127_4580494_5	143224.JQMD01000002_gene2107	2.01e-37	141.0	COG1983@1|root,COG1983@2|Bacteria,4NSQE@976|Bacteroidetes,1I55A@117743|Flavobacteriia	976|Bacteroidetes	KT	PspC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4580494_4	313596.RB2501_02165	4.175e-40	149.0	COG0607@1|root,COG0607@2|Bacteria,4NTEZ@976|Bacteroidetes,1I4AC@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_459575_2	313596.RB2501_11222	9.817e-121	390.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,1HWS5@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotide phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS2_k127_459575_0	313596.RB2501_11227	1.034e-229	720.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS2_k127_459575_1	313596.RB2501_11232	4.544e-151	482.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
CMS2_k127_459575_4	688270.Celal_0360	2.189e-28	115.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia,1FAJK@104264|Cellulophaga	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_459575_3	1250232.JQNJ01000001_gene272	3.35e-51	182.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS2_k127_4605365_3	313596.RB2501_02895	2.537e-32	126.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1HWZ0@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS2_k127_4605365_2	313596.RB2501_02890	5.619e-42	157.0	2C8IP@1|root,32RM9@2|Bacteria,4NSFN@976|Bacteroidetes,1I40E@117743|Flavobacteriia	976|Bacteroidetes	-	-	mraW	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4605365_0	313596.RB2501_02885	0.0	1176.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1HXSX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
CMS2_k127_4605365_1	313596.RB2501_02880	2.349e-229	718.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1HXA8@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_4610096_5	1218108.KB908291_gene747	3.082e-63	223.0	COG0500@1|root,COG2226@2|Bacteria,4NJ84@976|Bacteroidetes,1HXEK@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,NodS
CMS2_k127_4610096_8	1317122.ATO12_17820	5.347e-32	129.0	COG3832@1|root,COG3832@2|Bacteria,4NPAB@976|Bacteroidetes,1I2GF@117743|Flavobacteriia,2YKHY@290174|Aquimarina	976|Bacteroidetes	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS2_k127_4610096_1	869213.JCM21142_41395	1.18e-241	753.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
CMS2_k127_4610096_3	869213.JCM21142_41394	2.804e-122	399.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
CMS2_k127_4610096_2	869213.JCM21142_41393	1.592e-134	439.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,4NGUP@976|Bacteroidetes	976|Bacteroidetes	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
CMS2_k127_4610096_4	980584.AFPB01000066_gene3350	5.34e-69	241.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1HXI2@117743|Flavobacteriia,406IS@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS2_k127_4610096_9	1250232.JQNJ01000001_gene3508	7.613e-21	93.0	COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,1HYHM@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_4610096_6	504472.Slin_5238	1.26e-55	198.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,47QGD@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS2_k127_4610096_7	313596.RB2501_10672	3.924e-44	168.0	COG3797@1|root,COG3797@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS2_k127_4610096_0	1122179.KB890431_gene4241	1.154e-256	801.0	COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4647308_2	313596.RB2501_07480	5.831e-58	201.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,1HXRU@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_4647308_0	313596.RB2501_07485	0.0	1112.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CMS2_k127_4647308_1	313596.RB2501_07490	7.855e-248	769.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
CMS2_k127_4651799_4	1392490.JHZX01000001_gene426	8.18e-26	108.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS2_k127_4651799_0	313596.RB2501_12407	0.0	1201.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1HX1R@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS2_k127_4651799_3	1121011.AUCB01000024_gene3244	3.826e-26	109.0	2E37G@1|root,32Y75@2|Bacteria,4NV4S@976|Bacteroidetes,1I5D1@117743|Flavobacteriia,23HJP@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4651799_1	313596.RB2501_12422	9.99e-144	467.0	COG1929@1|root,COG1929@2|Bacteria,4NFK8@976|Bacteroidetes,1HXJ7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
CMS2_k127_4651799_2	313596.RB2501_12427	3.482e-30	120.0	28PKM@1|root,300JA@2|Bacteria,4NMW7@976|Bacteroidetes,1I276@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
CMS2_k127_4661127_2	313596.RB2501_07560	9.581e-168	535.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS2_k127_4661127_0	313596.RB2501_07555	8.163e-276	852.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS2_k127_4661127_4	313596.RB2501_07550	1.238e-50	183.0	2E4I5@1|root,32ZD8@2|Bacteria,4NV9B@976|Bacteroidetes,1I50D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4661127_3	313596.RB2501_07545	9.113e-141	449.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1HWRQ@117743|Flavobacteriia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS2_k127_4661127_1	313596.RB2501_07540	3.445e-255	788.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1HWXE@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS2_k127_4661127_5	1004149.AFOE01000049_gene1936	7.289e-39	147.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1I3VI@117743|Flavobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS2_k127_4661127_6	313596.RB2501_07530	7.165e-10	60.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1I19R@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS2_k127_4668912_8	616991.JPOO01000001_gene4498	1.092e-37	144.0	29EPR@1|root,301MK@2|Bacteria,4NQPA@976|Bacteroidetes,1I2MQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4668912_0	886377.Murru_0441	4.513e-218	691.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS2_k127_4668912_3	313596.RB2501_09595	1.624e-81	283.0	28HPY@1|root,2Z7XS@2|Bacteria,4NJIW@976|Bacteroidetes,1HZBP@117743|Flavobacteriia	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
CMS2_k127_4668912_7	313603.FB2170_00410	7.71e-58	204.0	COG5502@1|root,COG5502@2|Bacteria,4NN8N@976|Bacteroidetes,1I1CJ@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
CMS2_k127_4668912_2	313603.FB2170_00405	2.145e-90	312.0	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia	976|Bacteroidetes	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS2_k127_4668912_6	886377.Murru_2232	1.794e-67	237.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1I1DS@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS2_k127_4668912_1	313596.RB2501_09600	1.195e-125	407.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_4668912_5	616991.JPOO01000001_gene4458	2.14e-72	254.0	COG0589@1|root,COG0589@2|Bacteria,4NFS1@976|Bacteroidetes,1HZIQ@117743|Flavobacteriia,23G45@178469|Arenibacter	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_4668912_4	616991.JPOO01000001_gene4491	1.46e-74	259.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1I2IR@117743|Flavobacteriia,23IHQ@178469|Arenibacter	976|Bacteroidetes	T	Universal stress protein family	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
CMS2_k127_4680048_0	313596.RB2501_10587	1.439e-148	475.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS2_k127_4680048_1	1348583.ATLH01000005_gene936	2.933e-90	303.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia,1F7U8@104264|Cellulophaga	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS2_k127_4680048_3	1121875.KB907547_gene3425	9.174e-52	191.0	2F6NY@1|root,33Z5D@2|Bacteria,4P4RE@976|Bacteroidetes,1I9WX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4680048_2	313596.RB2501_10577	1.609e-77	263.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS2_k127_4680048_4	665571.STHERM_c15490	2.458e-37	149.0	2E8ZQ@1|root,33397@2|Bacteria,2J942@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4691790_0	1121875.KB907547_gene2936	0.0	1045.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
CMS2_k127_4691790_3	398720.MED217_15225	1.213e-87	295.0	COG1051@1|root,COG1051@2|Bacteria,4PMRX@976|Bacteroidetes,1IJY0@117743|Flavobacteriia	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_4691790_2	313596.RB2501_04010	3.686e-285	884.0	COG2114@1|root,COG2114@2|Bacteria,4PMA6@976|Bacteroidetes,1IJPA@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,Guanylate_cyc
CMS2_k127_4691790_4	313596.RB2501_04015	8.871e-70	237.0	COG0745@1|root,COG0745@2|Bacteria,4NVP7@976|Bacteroidetes,1I5B4@117743|Flavobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_4691790_1	313596.RB2501_04020	2.38e-287	887.0	COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
CMS2_k127_4695617_8	313596.RB2501_04205	1.623e-80	271.0	COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,1IJB4@117743|Flavobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
CMS2_k127_4695617_6	313596.RB2501_04210	6.977e-95	323.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1HWQZ@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphotransferase enzyme family	nahK	-	-	-	-	-	-	-	-	-	-	-	APH
CMS2_k127_4695617_1	1121875.KB907550_gene796	5.578e-238	738.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_4695617_3	313603.FB2170_03995	1.293e-174	555.0	COG4638@1|root,COG4638@2|Bacteria,4NJ33@976|Bacteroidetes,1HZFM@117743|Flavobacteriia	976|Bacteroidetes	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
CMS2_k127_4695617_4	1121875.KB907550_gene794	2.44e-168	539.0	COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,1HYXV@117743|Flavobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294,ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
CMS2_k127_4695617_5	1121875.KB907550_gene793	4.593e-108	357.0	COG1834@1|root,COG1834@2|Bacteria,4NGKJ@976|Bacteroidetes,1I0NU@117743|Flavobacteriia	976|Bacteroidetes	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS2_k127_4695617_7	313603.FB2170_03980	2.111e-85	290.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,1HWPP@117743|Flavobacteriia,2PGDY@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase (PrmA)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
CMS2_k127_4695617_2	313596.RB2501_04225	6.18e-233	730.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS2_k127_4695617_0	313596.RB2501_04230	0.0	1359.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,1HX7C@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2
CMS2_k127_4695617_9	313596.RB2501_04235	5.363e-56	203.0	COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,1I079@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_4703055_2	313596.RB2501_03850	1.694e-107	351.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia	976|Bacteroidetes	K	RNA polymerase sigma54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS2_k127_4703055_0	313596.RB2501_03845	2.586e-262	814.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1HWYW@117743|Flavobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS2_k127_4703055_1	313596.RB2501_03840	3.403e-220	690.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS2_k127_47258_1	1250232.JQNJ01000001_gene2743	1.19e-87	304.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_47258_0	926549.KI421517_gene1644	1.105e-295	915.0	COG0129@1|root,COG0129@2|Bacteria,4NEKY@976|Bacteroidetes,47K3U@768503|Cytophagia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
CMS2_k127_47258_2	313596.RB2501_00976	1.029e-71	248.0	COG1028@1|root,COG1028@2|Bacteria,4NF64@976|Bacteroidetes,1I22H@117743|Flavobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_4780845_8	1280944.HY17_16170	1.714e-38	151.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
CMS2_k127_4780845_4	313596.RB2501_09575	1.472e-156	499.0	COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,1HXBT@117743|Flavobacteriia	976|Bacteroidetes	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS2_k127_4780845_6	1121875.KB907546_gene2237	8.377e-128	411.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1HZJ2@117743|Flavobacteriia	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS2_k127_4780845_1	655815.ZPR_4334	0.0	1020.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,1HZIM@117743|Flavobacteriia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
CMS2_k127_4780845_0	760192.Halhy_0750	0.0	1122.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,1IQJ2@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	cbgA_1	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS2_k127_4780845_7	313596.RB2501_09560	4.641e-120	390.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1HWN3@117743|Flavobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_4780845_3	313596.RB2501_09555	1.844e-269	837.0	COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,1HZE1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CMS2_k127_4780845_2	1250232.JQNJ01000001_gene511	7.613e-285	888.0	COG3534@1|root,COG3534@2|Bacteria,4NGKW@976|Bacteroidetes,1HZE9@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C,CBM_4_9
CMS2_k127_4780845_5	313596.RB2501_09550	1.347e-147	470.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,1HZHT@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CMS2_k127_4813038_7	1121875.KB907546_gene2693	1.577e-48	181.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_4813038_5	1121875.KB907546_gene2694	5.786e-75	262.0	COG3712@1|root,COG3712@2|Bacteria,4NJA2@976|Bacteroidetes,1HYI5@117743|Flavobacteriia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
CMS2_k127_4813038_6	1121875.KB907546_gene2695	4.431e-73	250.0	COG1595@1|root,COG1595@2|Bacteria,4NMSP@976|Bacteroidetes,1I1J2@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_4813038_4	1121875.KB907546_gene2696	1.957e-102	345.0	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4813038_3	1121875.KB907546_gene2697	8.172e-116	380.0	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4813038_1	1121875.KB907548_gene1491	4.392e-141	470.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
CMS2_k127_4813038_8	1121875.KB907549_gene2064	3.572e-23	104.0	COG2044@1|root,COG2044@2|Bacteria,4P2I4@976|Bacteroidetes,1I8SH@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS2_k127_4813038_0	1121875.KB907546_gene2759	2.907e-318	987.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS2_k127_4813038_2	313596.RB2501_14259	1.405e-123	400.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1HZ91@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_482354_3	1121875.KB907546_gene2504	1.778e-86	290.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,1I2DE@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Fn3_assoc,Metallophos,PA14
CMS2_k127_482354_5	1249975.JQLP01000005_gene598	1.914e-21	96.0	2DNXG@1|root,32ZNF@2|Bacteria,4NV9Z@976|Bacteroidetes,1I563@117743|Flavobacteriia,2P739@244698|Gillisia	976|Bacteroidetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
CMS2_k127_482354_2	1250232.JQNJ01000001_gene755	7.848e-188	596.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1HYGI@117743|Flavobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_482354_0	313596.RB2501_09045	0.0	1752.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS2_k127_482354_1	313596.RB2501_09040	2.634e-192	604.0	COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,1HY9N@117743|Flavobacteriia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS2_k127_482354_4	313596.RB2501_09035	4.488e-29	117.0	COG4886@1|root,COG4886@2|Bacteria,4NI2K@976|Bacteroidetes,1I0CI@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Leucine Rich Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_4,LRR_8
CMS2_k127_482583_5	553177.CAPSP0001_0387	6.024e-23	98.0	COG1541@1|root,COG1541@2|Bacteria,4PKAN@976|Bacteroidetes,1HX4F@117743|Flavobacteriia,1ETI6@1016|Capnocytophaga	976|Bacteroidetes	H	Acyl-protein synthetase, LuxE	luxE	-	-	-	-	-	-	-	-	-	-	-	LuxE
CMS2_k127_482583_0	313596.RB2501_08385	6.557e-237	738.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS2_k127_482583_3	313596.RB2501_08380	4.864e-101	339.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
CMS2_k127_482583_4	313596.RB2501_08375	2.208e-34	136.0	2E5JY@1|root,330B6@2|Bacteria,4NV2G@976|Bacteroidetes,1I56S@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
CMS2_k127_482583_1	313596.RB2501_08370	1.228e-231	722.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1HXNI@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_482583_2	313596.RB2501_08365	6.487e-134	431.0	COG0463@1|root,COG0463@2|Bacteria,4PM68@976|Bacteroidetes,1IJKP@117743|Flavobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS2_k127_482583_6	886377.Murru_0995	6.057e-06	57.0	COG1807@1|root,COG1807@2|Bacteria,4NEU7@976|Bacteroidetes,1HZQP@117743|Flavobacteriia	976|Bacteroidetes	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS2_k127_4838801_1	313596.RB2501_15664	7.112e-93	308.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1HY1C@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_4838801_3	313603.FB2170_12811	7.055e-31	121.0	2E4WC@1|root,32ZQG@2|Bacteria,4NUNE@976|Bacteroidetes,1I503@117743|Flavobacteriia,2PHSN@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4838801_0	313596.RB2501_15654	0.0	1034.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HXQY@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_4838801_2	313596.RB2501_15639	1.083e-91	308.0	COG2220@1|root,COG2220@2|Bacteria,4NFJ4@976|Bacteroidetes,1HYS8@117743|Flavobacteriia	976|Bacteroidetes	S	of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS2_k127_4851497_3	313596.RB2501_14289	4.142e-86	287.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS2_k127_4851497_6	313596.RB2501_14294	1.27e-46	170.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1I2YQ@117743|Flavobacteriia	976|Bacteroidetes	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS2_k127_4851497_1	1347342.BN863_24360	7.654e-236	738.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,1HWVE@117743|Flavobacteriia	976|Bacteroidetes	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
CMS2_k127_4851497_2	313596.RB2501_14304	3.713e-215	672.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-lyase	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS2_k127_4851497_4	313596.RB2501_14309	2.184e-67	233.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I2AJ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS2_k127_4851497_0	313596.RB2501_14314	2.214e-256	795.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWJZ@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS2_k127_4851497_5	313596.RB2501_14319	1.344e-49	182.0	COG3503@1|root,COG3503@2|Bacteria,4NG0X@976|Bacteroidetes,1HWX2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS2_k127_4857044_2	313596.RB2501_11832	5.178e-61	213.0	COG0526@1|root,COG0526@2|Bacteria,4NNPY@976|Bacteroidetes,1I228@117743|Flavobacteriia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS2_k127_4857044_0	313596.RB2501_11827	0.0	1423.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS2_k127_4857044_3	313596.RB2501_13459	2.021e-60	212.0	COG2032@1|root,COG2032@2|Bacteria,4NGGW@976|Bacteroidetes,1HY8P@117743|Flavobacteriia	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CMS2_k127_4857044_1	313596.RB2501_13459	1.135e-61	218.0	COG2032@1|root,COG2032@2|Bacteria,4NGGW@976|Bacteroidetes,1HY8P@117743|Flavobacteriia	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CMS2_k127_4875498_8	1250232.JQNJ01000001_gene2746	7.452e-37	143.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia	976|Bacteroidetes	P	COG3420 Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
CMS2_k127_4875498_7	1046627.BZARG_1501	3.03e-43	164.0	COG4314@1|root,COG4314@2|Bacteria,4NVVP@976|Bacteroidetes,1I2Z0@117743|Flavobacteriia	976|Bacteroidetes	C	NosL	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS2_k127_4875498_2	313603.FB2170_03795	4.465e-100	328.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1HXI6@117743|Flavobacteriia,2PIQX@252356|Maribacter	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS2_k127_4875498_0	313603.FB2170_03800	0.0	1206.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,2PIK7@252356|Maribacter	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS2_k127_4875498_3	1250232.JQNJ01000001_gene2751	4.331e-77	262.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia	976|Bacteroidetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS2_k127_4875498_4	313603.FB2170_03810	2.97e-66	230.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1I1GF@117743|Flavobacteriia,2PIMA@252356|Maribacter	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_4875498_6	1250232.JQNJ01000001_gene2753	7.211e-51	184.0	COG1959@1|root,COG1959@2|Bacteria,4NPHI@976|Bacteroidetes,1I2QC@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS2_k127_4875498_5	313596.RB2501_05475	3.137e-54	196.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1I1GF@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_4875498_1	313596.RB2501_00961	1.592e-169	541.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,1IIHC@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS2_k127_488159_4	313596.RB2501_00446	1.597e-88	300.0	COG4538@1|root,COG4538@2|Bacteria,4PKKQ@976|Bacteroidetes,1HYE5@117743|Flavobacteriia	976|Bacteroidetes	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SnoaL_2
CMS2_k127_488159_1	1250232.JQNJ01000001_gene3766	1.935e-227	711.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1HX25@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
CMS2_k127_488159_0	313596.RB2501_00466	1.345e-283	879.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS2_k127_488159_2	313596.RB2501_00471	2.336e-218	683.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HZRU@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_488159_3	313596.RB2501_00476	1.48e-181	576.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,1HZM2@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Trehalose utilisation	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA
CMS2_k127_4883453_0	313596.RB2501_00841	2.377e-185	588.0	COG0025@1|root,COG0025@2|Bacteria,4NF54@976|Bacteroidetes,1HYT6@117743|Flavobacteriia	976|Bacteroidetes	P	sodium proton antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS2_k127_4883453_1	865937.Gilli_3385	1.523e-141	463.0	28JFD@1|root,2Z99B@2|Bacteria,4NFQJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OprD
CMS2_k127_4897535_5	313596.RB2501_09785	9.006e-138	441.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4897535_7	313596.RB2501_09780	1.525e-80	274.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1HXJ3@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS2_k127_4897535_9	313596.RB2501_09775	3.75e-57	203.0	294EW@1|root,2ZRUR@2|Bacteria,4NPA3@976|Bacteroidetes,1I38U@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
CMS2_k127_4897535_1	313596.RB2501_09770	7.174e-229	717.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan synthetase	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_4897535_6	313596.RB2501_09760	4.111e-117	388.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1HY8Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_4897535_10	313596.RB2501_09755	3.137e-56	204.0	2DM2K@1|root,31G7J@2|Bacteria,4NQIU@976|Bacteroidetes,1I2UQ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS2_k127_4897535_4	313596.RB2501_09750	8.892e-183	575.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1HXN1@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS2_k127_4897535_3	313596.RB2501_09745	1.908e-191	602.0	COG0563@1|root,COG0634@1|root,COG0563@2|Bacteria,COG0634@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
CMS2_k127_4897535_2	313596.RB2501_09740	5.78e-199	625.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1HXZB@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CMS2_k127_4897535_8	313596.RB2501_09735	1.246e-74	253.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS2_k127_4897535_0	313596.RB2501_09730	1.238e-310	963.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS2_k127_490263_4	313596.RB2501_06735	9.046e-138	445.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1HX7N@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS2_k127_490263_5	313603.FB2170_05820	1.921e-80	279.0	2C1V9@1|root,3098U@2|Bacteria,4NP7M@976|Bacteroidetes,1IEAC@117743|Flavobacteriia,2PGSD@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_490263_1	313596.RB2501_06745	6.497e-306	943.0	COG0664@1|root,COG0664@2|Bacteria,4NEWA@976|Bacteroidetes,1HWPV@117743|Flavobacteriia	976|Bacteroidetes	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_490263_2	313596.RB2501_06750	2.673e-256	796.0	COG0318@1|root,COG0318@2|Bacteria,4NDYR@976|Bacteroidetes,1HXTW@117743|Flavobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS2_k127_490263_3	313596.RB2501_06755	2.379e-162	514.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_490263_6	313596.RB2501_06760	1.498e-23	100.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS2_k127_490263_0	313596.RB2501_06765	1.889e-317	992.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,SPOR
CMS2_k127_4904649_0	313596.RB2501_00796	5.346e-236	738.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS2_k127_4904649_5	1380600.AUYN01000006_gene371	3.665e-62	220.0	COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,1I0ZH@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CMS2_k127_4904649_4	1121007.AUML01000026_gene1827	1.294e-88	298.0	COG3182@1|root,COG3182@2|Bacteria,4NFK9@976|Bacteroidetes,1HWKV@117743|Flavobacteriia,2YHN4@290174|Aquimarina	976|Bacteroidetes	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
CMS2_k127_4904649_2	313596.RB2501_00786	3.479e-196	627.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1HYRA@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4
CMS2_k127_4904649_1	616991.JPOO01000001_gene4514	6.17e-207	658.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia,23G8D@178469|Arenibacter	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS2_k127_4904649_3	313596.RB2501_00781	4.648e-183	575.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1HXE2@117743|Flavobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_4904649_6	313596.RB2501_00776	6.202e-37	140.0	2DTB4@1|root,32UUV@2|Bacteria,4NSRC@976|Bacteroidetes,1I40G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4913916_1	313596.RB2501_09325	1e-323	1004.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
CMS2_k127_4913916_0	313596.RB2501_09320	0.0	1896.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD,Sortilin-Vps10,TSP_3
CMS2_k127_4913916_2	313596.RB2501_09315	5.17e-86	290.0	COG4733@1|root,COG4733@2|Bacteria,4NQRS@976|Bacteroidetes,1I3C0@117743|Flavobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4913916_3	1237149.C900_04953	2.788e-13	75.0	2AM3F@1|root,31BXJ@2|Bacteria,4NPAN@976|Bacteroidetes,47PK8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4913945_1	313596.RB2501_00025	3.972e-105	346.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,1HY5I@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
CMS2_k127_4913945_0	313596.RB2501_00030	5.607e-215	669.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1HWZT@117743|Flavobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS2_k127_4913945_3	313596.RB2501_00035	7.971e-81	273.0	COG1443@1|root,COG1443@2|Bacteria,4NRS2@976|Bacteroidetes,1I2UY@117743|Flavobacteriia	976|Bacteroidetes	I	Hydrolase of MutT (Nudix) family protein	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_4913945_2	313596.RB2501_00040	7.408e-91	303.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1HX0E@117743|Flavobacteriia	976|Bacteroidetes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS2_k127_4915272_3	1121875.KB907547_gene3004	4.473e-89	294.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia	976|Bacteroidetes	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS2_k127_4915272_2	313596.RB2501_08935	8.217e-119	387.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,1HWJM@117743|Flavobacteriia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS2_k127_4915272_6	688270.Celal_0906	1.183e-49	182.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1I35P@117743|Flavobacteriia,1FACX@104264|Cellulophaga	976|Bacteroidetes	S	TIGRFAM rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4915272_0	313596.RB2501_08925	0.0	1152.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS2_k127_4915272_1	1121012.AUKX01000013_gene2117	5.578e-179	569.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1HXI4@117743|Flavobacteriia,23FUM@178469|Arenibacter	976|Bacteroidetes	D	Cell cycle protein	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS2_k127_4915272_7	313596.RB2501_08915	5.393e-46	173.0	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes,1HYJF@117743|Flavobacteriia	976|Bacteroidetes	F	COG1864 DNA RNA endonuclease G, NUC1	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
CMS2_k127_4915272_9	1392498.JQLH01000001_gene3488	2.426e-16	84.0	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes,1HYJF@117743|Flavobacteriia,2PGYG@252356|Maribacter	976|Bacteroidetes	F	DNA/RNA non-specific endonuclease	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
CMS2_k127_4915272_5	1249997.JHZW01000002_gene1609	5.04e-81	273.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I20A@117743|Flavobacteriia,2PHBZ@252356|Maribacter	976|Bacteroidetes	O	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS2_k127_4915272_4	313596.RB2501_08905	1.998e-84	283.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HX5F@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS2_k127_4915272_8	616991.JPOO01000003_gene650	6.811e-40	156.0	COG1917@1|root,COG1917@2|Bacteria,4NS3U@976|Bacteroidetes,1I3FI@117743|Flavobacteriia,23IBR@178469|Arenibacter	976|Bacteroidetes	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,DUF4437
CMS2_k127_4918498_1	1121875.KB907550_gene648	7.558e-136	441.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1HY79@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalase	treA	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase,Trehalase_Ca-bi
CMS2_k127_4918498_2	313596.RB2501_05225	4.374e-106	349.0	COG0457@1|root,COG0457@2|Bacteria,4NM69@976|Bacteroidetes,1I0UE@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4918498_3	313596.RB2501_05215	5.087e-76	263.0	COG0451@1|root,COG0451@2|Bacteria,4NMWC@976|Bacteroidetes,1I18Q@117743|Flavobacteriia	976|Bacteroidetes	GM	COG0451 Nucleoside-diphosphate-sugar	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,NAD_binding_2
CMS2_k127_4918498_0	313596.RB2501_05210	9.353e-309	960.0	COG2234@1|root,COG2234@2|Bacteria,4PKJJ@976|Bacteroidetes,1HX9M@117743|Flavobacteriia	976|Bacteroidetes	G	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS2_k127_4933976_3	313596.RB2501_09730	1.747e-34	132.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS2_k127_4933976_4	1121011.AUCB01000005_gene2449	5.563e-33	131.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia,23HKJ@178469|Arenibacter	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
CMS2_k127_4933976_2	313596.RB2501_09720	1.173e-86	289.0	COG1595@1|root,COG1595@2|Bacteria,4NHNI@976|Bacteroidetes,1HY4K@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_4933976_5	313596.RB2501_09715	1.561e-21	95.0	2DP5F@1|root,330KU@2|Bacteria,4NV42@976|Bacteroidetes,1I5KT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4933976_1	313596.RB2501_09710	1.736e-91	311.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1HWRB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4933976_0	313596.RB2501_09705	0.0	1230.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
CMS2_k127_4938731_3	313596.RB2501_02000	4.735e-131	425.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,1HXBP@117743|Flavobacteriia	976|Bacteroidetes	G	isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS2_k127_4938731_8	313603.FB2170_16101	1.103e-26	112.0	2E43R@1|root,32Z02@2|Bacteria,4NVFS@976|Bacteroidetes,1I51B@117743|Flavobacteriia,2PHST@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4938731_5	313596.RB2501_01990	1.098e-86	293.0	28V2E@1|root,2ZH5W@2|Bacteria,4NH6Z@976|Bacteroidetes,1I04G@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369
CMS2_k127_4938731_2	313596.RB2501_01980	3.004e-221	691.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1HX29@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS2_k127_4938731_0	313596.RB2501_01975	0.0	1135.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_4938731_1	313596.RB2501_01970	0.0	1009.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HX1V@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS2_k127_4938731_4	313596.RB2501_01965	2.429e-112	368.0	28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,1HZ0J@117743|Flavobacteriia	976|Bacteroidetes	S	S1 P1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
CMS2_k127_4938731_6	313596.RB2501_01945	7.961e-69	239.0	COG2258@1|root,COG2258@2|Bacteria,4NGQN@976|Bacteroidetes,1I049@117743|Flavobacteriia	976|Bacteroidetes	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS2_k127_4938731_7	313596.RB2501_01940	3.634e-50	181.0	2E0NT@1|root,32W7U@2|Bacteria,4NTP9@976|Bacteroidetes,1I4V2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4949132_3	1237149.C900_02070	9.258e-70	241.0	COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
CMS2_k127_4949132_5	136037.KDR22010	8.172e-05	47.0	KOG0773@1|root,KOG0773@2759|Eukaryota,39S2F@33154|Opisthokonta,3BBCP@33208|Metazoa,3CRXU@33213|Bilateria,41VZ5@6656|Arthropoda,3SKVA@50557|Insecta	33208|Metazoa	K	DNA binding. It is involved in the biological process described with regulation of transcription, DNA-templated	TGIF1	GO:0000003,GO:0000122,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000982,GO:0000987,GO:0001012,GO:0001067,GO:0001077,GO:0001078,GO:0001227,GO:0001228,GO:0001654,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0003002,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003712,GO:0003714,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007275,GO:0007276,GO:0007283,GO:0007368,GO:0007389,GO:0007399,GO:0007423,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0008432,GO:0009058,GO:0009059,GO:0009653,GO:0009790,GO:0009792,GO:0009799,GO:0009855,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010470,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0010720,GO:0014020,GO:0016070,GO:0016331,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0021915,GO:0022008,GO:0022414,GO:0022603,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032774,GO:0032924,GO:0034641,GO:0034645,GO:0034654,GO:0035148,GO:0035239,GO:0035295,GO:0038092,GO:0042127,GO:0043009,GO:0043010,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0045995,GO:0046332,GO:0046483,GO:0048145,GO:0048146,GO:0048232,GO:0048385,GO:0048387,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048598,GO:0048609,GO:0048646,GO:0048699,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051716,GO:0051960,GO:0051962,GO:0060041,GO:0060255,GO:0060284,GO:0060429,GO:0060562,GO:0060606,GO:0065007,GO:0070013,GO:0070410,GO:0071704,GO:0072175,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000026,GO:2000112,GO:2000113,GO:2001141	-	ko:K19383,ko:K19553	ko04350,map04350	-	-	-	ko00000,ko00001,ko03000	-	-	-	Homeobox_KN
CMS2_k127_4949132_0	313596.RB2501_00271	0.0	1784.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS2_k127_4949132_4	313596.RB2501_00276	3.933e-21	93.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1I50B@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS2_k127_4949132_2	143224.JQMD01000002_gene469	1.526e-75	263.0	2E676@1|root,2ZBSV@2|Bacteria,4NN7A@976|Bacteroidetes,1II99@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4949132_1	313596.RB2501_00286	8.698e-85	283.0	28J86@1|root,2Z93E@2|Bacteria,4NJYR@976|Bacteroidetes,1I0EG@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4951833_5	313596.RB2501_06425	0.0004585	44.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1HY5F@117743|Flavobacteriia	976|Bacteroidetes	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS2_k127_4951833_0	313596.RB2501_06430	0.0	1312.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS2_k127_4951833_3	313596.RB2501_06435	5.006e-54	196.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1I2XD@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
CMS2_k127_4951833_1	1250232.JQNJ01000001_gene1335	1.262e-205	644.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
CMS2_k127_4951833_2	313596.RB2501_06445	4.816e-189	597.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
CMS2_k127_4951833_4	143224.JQMD01000002_gene3227	3.256e-38	143.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1HY3S@117743|Flavobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS2_k127_4952425_2	313596.RB2501_13229	7.142e-162	514.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
CMS2_k127_4952425_0	313596.RB2501_13234	1.855e-190	597.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1HWWG@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS2_k127_4952425_1	886377.Murru_2295	8.899e-184	578.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HYY3@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS2_k127_4952425_3	143224.JQMD01000002_gene1449	2.1e-31	124.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1HXM2@117743|Flavobacteriia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS2_k127_4959401_8	313596.RB2501_02580	8.71e-45	164.0	COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol-disulfide isomerase and thioredoxins	txn	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
CMS2_k127_4959401_1	313596.RB2501_02585	8.946e-152	483.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1HXCX@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS2_k127_4959401_3	313596.RB2501_02590	1.653e-130	424.0	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,1HXEZ@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS2_k127_4959401_2	313596.RB2501_02595	5.301e-135	437.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS2_k127_4959401_7	313596.RB2501_02600	8.269e-55	194.0	2ADU8@1|root,313JX@2|Bacteria,4NQA4@976|Bacteroidetes,1I2S9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4959401_0	313596.RB2501_02605	6.737e-280	861.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,1HWV9@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS2_k127_4959401_4	313596.RB2501_02610	1.562e-125	406.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,1HX59@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS2_k127_4959401_6	1348583.ATLH01000029_gene1129	2.941e-118	382.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,1HXGP@117743|Flavobacteriia,1F8K5@104264|Cellulophaga	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS2_k127_4959401_5	313596.RB2501_02620	1.51e-121	393.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,1HZG0@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
CMS2_k127_4959401_9	313603.FB2170_16716	7.571e-34	130.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia,2PG04@252356|Maribacter	976|Bacteroidetes	C	NQR2, RnfD, RnfE family	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
CMS2_k127_4960238_2	504472.Slin_2318	1.653e-117	388.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_4960238_3	1049564.TevJSym_am00450	2.243e-12	70.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1J4PD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_4960238_0	634956.Geoth_2367	1.726e-159	508.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1WFNM@129337|Geobacillus	91061|Bacilli	C	Transketolase, pyrimidine binding domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_4960238_1	235909.GK0710	2.125e-153	491.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli,1WG18@129337|Geobacillus	91061|Bacilli	C	Transketolase, thiamine diphosphate binding domain	acoA	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
CMS2_k127_4975304_3	313596.RB2501_06425	8.941e-113	365.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1HY5F@117743|Flavobacteriia	976|Bacteroidetes	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS2_k127_4975304_2	1250232.JQNJ01000001_gene1339	7.986e-122	397.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1HWRK@117743|Flavobacteriia	976|Bacteroidetes	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS2_k127_4975304_5	313596.RB2501_06410	5.384e-09	58.0	2EM2X@1|root,33ESE@2|Bacteria,4NYI9@976|Bacteroidetes,1I6UY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4975304_4	313596.RB2501_06405	8.162e-55	197.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,1I26T@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	paiA	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS2_k127_4975304_1	1250232.JQNJ01000001_gene1675	3.232e-175	556.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,1HYBE@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_4975304_0	313596.RB2501_06390	1.001e-180	572.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_4985817_6	313596.RB2501_03445	1.057e-41	154.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS2_k127_4985817_4	1317122.ATO12_01120	7.185e-98	327.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,1I19N@117743|Flavobacteriia,2YI2A@290174|Aquimarina	976|Bacteroidetes	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS2_k127_4985817_1	1122176.KB903532_gene2516	3.324e-264	826.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
CMS2_k127_4985817_0	1296416.JACB01000003_gene720	0.0	1566.0	COG3383@1|root,COG3383@2|Bacteria,4PKV4@976|Bacteroidetes,1IKVD@117743|Flavobacteriia,2YKIF@290174|Aquimarina	976|Bacteroidetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	hndD	-	1.12.1.3,1.17.1.9	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS2_k127_4985817_7	1121004.ATVC01000098_gene703	1.037e-11	72.0	COG0664@1|root,COG0664@2|Bacteria,1PEQ9@1224|Proteobacteria,2W9DI@28216|Betaproteobacteria,2KTHP@206351|Neisseriales	206351|Neisseriales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS2_k127_4985817_2	1121875.KB907548_gene1638	1.152e-220	692.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4985817_3	886377.Murru_1896	5.692e-146	466.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia	976|Bacteroidetes	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS2_k127_4985817_5	313596.RB2501_03425	3.013e-53	201.0	COG1361@1|root,COG2730@1|root,COG2885@1|root,COG3209@1|root,COG1361@2|Bacteria,COG2730@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,4NG16@976|Bacteroidetes,1HY10@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SdrD_B
CMS2_k127_499463_2	313596.RB2501_09250	4.588e-94	312.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1HYCP@117743|Flavobacteriia	976|Bacteroidetes	NU	Mannosyl-glycoprotein	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
CMS2_k127_499463_1	313596.RB2501_09255	4.723e-226	706.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1HWQS@117743|Flavobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_499463_0	313596.RB2501_09275	1.38e-248	773.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS2_k127_499463_3	313596.RB2501_09280	3.484e-28	114.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
CMS2_k127_5007379_8	616991.JPOO01000001_gene3836	2.61e-07	53.0	2BAFY@1|root,323WE@2|Bacteria,4NQ3E@976|Bacteroidetes,1I30F@117743|Flavobacteriia,23HCR@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5007379_5	1392498.JQLH01000001_gene2847	8.773e-82	276.0	COG1595@1|root,COG1595@2|Bacteria,4NFXX@976|Bacteroidetes,1HZT5@117743|Flavobacteriia,2PGYD@252356|Maribacter	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_5007379_0	313596.RB2501_12744	0.0	1366.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS2_k127_5007379_3	313596.RB2501_12749	5.504e-101	334.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS2_k127_5007379_1	1121875.KB907549_gene1823	0.0	1095.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1HXPG@117743|Flavobacteriia	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS2_k127_5007379_4	313596.RB2501_12764	2.991e-96	316.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1HXQM@117743|Flavobacteriia	976|Bacteroidetes	F	pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS2_k127_5007379_2	313603.FB2170_15238	3.603e-175	551.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1HXQ7@117743|Flavobacteriia,2PGU6@252356|Maribacter	976|Bacteroidetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS2_k127_5007379_6	313596.RB2501_12774	7.855e-47	170.0	2CP87@1|root,32SIN@2|Bacteria,4NS9S@976|Bacteroidetes,1I3VG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5007379_7	313596.RB2501_12779	7.501e-31	122.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS2_k127_5008881_15	1250232.JQNJ01000001_gene943	1.281e-12	69.0	COG2146@1|root,COG2146@2|Bacteria,4NP7U@976|Bacteroidetes,1I3AW@117743|Flavobacteriia	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5008881_6	313596.RB2501_08190	2.427e-81	273.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS2_k127_5008881_11	313596.RB2501_08195	1.585e-37	141.0	COG0640@1|root,COG0640@2|Bacteria,4NS8H@976|Bacteroidetes,1I4BK@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS2_k127_5008881_7	313596.RB2501_08200	1.817e-76	261.0	COG5658@1|root,COG5658@2|Bacteria,4NNCF@976|Bacteroidetes,1I1PF@117743|Flavobacteriia	976|Bacteroidetes	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
CMS2_k127_5008881_9	313596.RB2501_08205	1.8e-56	199.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1I1YY@117743|Flavobacteriia	976|Bacteroidetes	FG	HIT family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS2_k127_5008881_12	313596.RB2501_08210	2.515e-34	137.0	2E6VJ@1|root,331F5@2|Bacteria,4NUPN@976|Bacteroidetes,1I5JT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5008881_0	313596.RB2501_08215	2.665e-209	654.0	COG5000@1|root,COG5000@2|Bacteria,4PKJN@976|Bacteroidetes,1IJB1@117743|Flavobacteriia	976|Bacteroidetes	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_5008881_2	313596.RB2501_08220	3.05e-126	410.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS2_k127_5008881_8	1004149.AFOE01000002_gene2251	4.403e-61	212.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
CMS2_k127_5008881_1	313596.RB2501_08230	2.686e-178	569.0	COG2031@1|root,COG2031@2|Bacteria,4NIRP@976|Bacteroidetes,1HWM3@117743|Flavobacteriia	976|Bacteroidetes	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
CMS2_k127_5008881_4	313596.RB2501_08235	7.23e-94	312.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1HY9J@117743|Flavobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS2_k127_5008881_10	313596.RB2501_08245	6.148e-45	169.0	2C0PB@1|root,331E0@2|Bacteria,4NUMG@976|Bacteroidetes,1I58I@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5008881_3	313596.RB2501_08250	3.329e-98	322.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1HYH3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS2_k127_5008881_14	1392498.JQLH01000001_gene1350	2.486e-15	81.0	2E4GQ@1|root,32ZBW@2|Bacteria,4NWCC@976|Bacteroidetes,1I57G@117743|Flavobacteriia,2PIPD@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5008881_5	1348583.ATLH01000001_gene3790	9.509e-85	287.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,1HZEU@117743|Flavobacteriia,1F8F4@104264|Cellulophaga	976|Bacteroidetes	K	PFAM Transcription regulator, TetR-like, DNA-binding, bacterial archaeal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_5008881_13	906888.JCM19314_3476	3.317e-18	86.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia,3HJCV@363408|Nonlabens	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS2_k127_5055178_0	313596.RB2501_02290	1.782e-258	806.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1HYNG@117743|Flavobacteriia	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_5055178_1	313596.RB2501_02295	1.408e-94	312.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1HZFF@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_5057300_0	313596.RB2501_10050	1.572e-319	989.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5072102_1	313596.RB2501_08850	2.486e-91	303.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
CMS2_k127_5072102_0	313596.RB2501_08845	2.567e-207	653.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS2_k127_5072102_2	1121875.KB907547_gene3025	8.567e-23	99.0	2DQIW@1|root,33758@2|Bacteria,4NV6U@976|Bacteroidetes,1I5DB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5075822_2	1123248.KB893320_gene3928	5.784e-29	119.0	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,1IQ14@117747|Sphingobacteriia	976|Bacteroidetes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS2_k127_5075822_1	761193.Runsl_1022	2.435e-87	302.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,47JA8@768503|Cytophagia	976|Bacteroidetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS2_k127_5075822_0	929562.Emtol_2016	5.58e-119	395.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,47M8R@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS2_k127_5075822_3	313596.RB2501_14934	5.052e-18	86.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia	976|Bacteroidetes	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CMS2_k127_5089870_4	700598.Niako_5157	2.502e-15	78.0	COG3427@1|root,COG3427@2|Bacteria,4NRMQ@976|Bacteroidetes	2|Bacteria	S	PFAM Carbon monoxide dehydrogenase subunit G (CoxG)	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS2_k127_5089870_0	700598.Niako_5158	0.0	1282.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,1IVK4@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS2_k127_5089870_2	518766.Rmar_2765	1.039e-72	248.0	COG2080@1|root,COG2080@2|Bacteria,4NPTH@976|Bacteroidetes	976|Bacteroidetes	C	PFAM 2Fe-2S binding	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_5089870_1	760192.Halhy_5285	1.481e-106	353.0	COG1319@1|root,COG1319@2|Bacteria,4NFT8@976|Bacteroidetes,1IV94@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS2_k127_5089870_3	1288963.ADIS_2511	2.481e-70	246.0	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,47KUY@768503|Cytophagia	976|Bacteroidetes	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS2_k127_5091897_1	313596.RB2501_11727	3.055e-193	604.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS2_k127_5091897_2	313596.RB2501_11722	3.093e-170	538.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS2_k127_5091897_5	313596.RB2501_11717	1.77e-139	452.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS2_k127_5091897_7	1506583.JQJY01000005_gene2300	3.117e-52	186.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,1I23Q@117743|Flavobacteriia,2NW8M@237|Flavobacterium	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS2_k127_5091897_4	313596.RB2501_11707	3.428e-146	466.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS2_k127_5091897_6	313596.RB2501_11702	1.622e-103	343.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS2_k127_5091897_3	313596.RB2501_11697	3.108e-149	482.0	28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,1HWQW@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CMS2_k127_5091897_0	313596.RB2501_11692	2.52e-297	928.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HY5T@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS2_k127_5093844_2	980584.AFPB01000088_gene242	7.333e-109	357.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,1HXBY@117743|Flavobacteriia,40660@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	J	RNA pseudouridylate synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
CMS2_k127_5093844_4	1004149.AFOE01000004_gene2284	7.686e-42	159.0	COG0597@1|root,COG0597@2|Bacteria,4NNP3@976|Bacteroidetes,1I23N@117743|Flavobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS2_k127_5093844_1	313596.RB2501_15784	3.122e-150	479.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1HXEE@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS2_k127_5093844_3	313596.RB2501_15779	7.435e-52	199.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,1I2T9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
CMS2_k127_5093844_0	313596.RB2501_15774	1.325e-244	760.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1HXUH@117743|Flavobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CMS2_k127_5094732_4	688270.Celal_0743	5.251e-79	267.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1HXFU@117743|Flavobacteriia,1F8ZT@104264|Cellulophaga	976|Bacteroidetes	M	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS2_k127_5094732_1	313596.RB2501_09675	4.749e-232	726.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1HXBV@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
CMS2_k127_5094732_2	616991.JPOO01000003_gene1564	3.298e-140	449.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1HXNN@117743|Flavobacteriia,23GJY@178469|Arenibacter	976|Bacteroidetes	Q	ATPases associated with a variety of cellular activities	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS2_k127_5094732_3	313596.RB2501_09685	1.399e-138	442.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS2_k127_5094732_0	313596.RB2501_09690	1.248e-251	786.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS2_k127_5113440_2	313596.RB2501_12677	6.545e-293	904.0	COG3281@1|root,COG3281@2|Bacteria,4PMAP@976|Bacteroidetes,1HZME@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalose synthase	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH
CMS2_k127_5113440_1	391587.KAOT1_09566	0.0	1037.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1HXCC@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS2_k127_5113440_0	313596.RB2501_12687	0.0	1531.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
CMS2_k127_5116679_2	313596.RB2501_15994	1.691e-75	259.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1I0BY@117743|Flavobacteriia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
CMS2_k127_5116679_1	313596.RB2501_15999	9.113e-135	436.0	COG1216@1|root,COG1216@2|Bacteria,4NFS6@976|Bacteroidetes,1IJCJ@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
CMS2_k127_5116679_0	1004149.AFOE01000017_gene792	1.832e-157	497.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1HYEY@117743|Flavobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_5121678_0	313596.RB2501_10125	2.275e-268	831.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I0C1@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_5121678_2	313596.RB2501_10120	1.623e-136	440.0	COG2267@1|root,COG2267@2|Bacteria,4PKB9@976|Bacteroidetes,1IJ6A@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
CMS2_k127_5121678_4	313596.RB2501_10115	1.517e-77	265.0	COG3565@1|root,COG3565@2|Bacteria,4NNHW@976|Bacteroidetes,1I212@117743|Flavobacteriia	976|Bacteroidetes	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_5121678_1	1121875.KB907546_gene2350	7.921e-182	571.0	COG0667@1|root,COG0667@2|Bacteria,4NHA1@976|Bacteroidetes,1HZQF@117743|Flavobacteriia	976|Bacteroidetes	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_5121678_3	143224.JQMD01000002_gene1996	1.753e-111	371.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,1HYIQ@117743|Flavobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CMS2_k127_5165812_6	313596.RB2501_02580	1.513e-10	63.0	COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol-disulfide isomerase and thioredoxins	txn	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
CMS2_k127_5165812_0	313596.RB2501_02575	1.012e-282	873.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1HWJU@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS2_k127_5165812_4	313603.FB2170_16661	1.04e-21	94.0	2E5KA@1|root,330BH@2|Bacteria,4NXD5@976|Bacteroidetes,1I5TV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5165812_7	1121011.AUCB01000005_gene2290	2.081e-09	59.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,1IMQR@117743|Flavobacteriia,23H6B@178469|Arenibacter	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS2_k127_5165812_2	313596.RB2501_02555	2.265e-108	352.0	COG1876@1|root,COG1876@2|Bacteria,4NFA4@976|Bacteroidetes,1HYP4@117743|Flavobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	-	-	-	-	-	-	-	-	-	-	VanY
CMS2_k127_5165812_8	313596.RB2501_02555	0.0003039	45.0	COG1876@1|root,COG1876@2|Bacteria,4NFA4@976|Bacteroidetes,1HYP4@117743|Flavobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	-	-	-	-	-	-	-	-	-	-	VanY
CMS2_k127_5165812_1	313596.RB2501_02550	5.542e-154	495.0	COG1361@1|root,COG1361@2|Bacteria,4NIPH@976|Bacteroidetes,1I08H@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS2_k127_5165812_5	1178825.ALIH01000006_gene1515	1.978e-13	80.0	2DP40@1|root,330F7@2|Bacteria,4NV4R@976|Bacteroidetes,1I5CM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5165812_3	1121012.AUKX01000069_gene2939	1.023e-21	105.0	COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1IEJC@117743|Flavobacteriia,23HZX@178469|Arenibacter	976|Bacteroidetes	MUW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
CMS2_k127_5166327_4	504487.JCM19302_4189	5.414e-22	103.0	COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,1HYC5@117743|Flavobacteriia	976|Bacteroidetes	H	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
CMS2_k127_5166327_2	313596.RB2501_06965	2.054e-157	507.0	COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,1HZQK@117743|Flavobacteriia	976|Bacteroidetes	E	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
CMS2_k127_5166327_0	313596.RB2501_06970	0.0	1004.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS2_k127_5166327_1	313596.RB2501_06975	2.107e-252	788.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS2_k127_5166327_3	313596.RB2501_06980	8.371e-127	409.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1HYGQ@117743|Flavobacteriia	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS2_k127_51706_0	313596.RB2501_07385	4.177e-279	865.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl endopeptidase	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS2_k127_51706_1	313596.RB2501_07390	3.112e-51	182.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_5184370_0	1121875.KB907549_gene1761	5.794e-295	914.0	COG0457@1|root,COG1874@1|root,COG3206@1|root,COG0457@2|Bacteria,COG1874@2|Bacteria,COG3206@2|Bacteria,4NH33@976|Bacteroidetes,1HYMC@117743|Flavobacteriia	976|Bacteroidetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5202501_0	313596.RB2501_10472	0.0	1191.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS2_k127_5229881_6	1250232.JQNJ01000001_gene3813	8.638e-36	138.0	28KSE@1|root,2ZBRS@2|Bacteria,4NNCR@976|Bacteroidetes,1I1W2@117743|Flavobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_5229881_0	313596.RB2501_02785	0.0	1047.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1HWUY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CMS2_k127_5229881_4	1121875.KB907556_gene556	3.78e-79	272.0	2A6M8@1|root,30VF2@2|Bacteria,4NNJ4@976|Bacteroidetes,1I2FJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
CMS2_k127_5229881_2	1317122.ATO12_17535	1.136e-87	294.0	COG3047@1|root,COG3047@2|Bacteria,4NPKA@976|Bacteroidetes,1I1SB@117743|Flavobacteriia,2YHZH@290174|Aquimarina	976|Bacteroidetes	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
CMS2_k127_5229881_5	313596.RB2501_02780	5.883e-73	252.0	2DRNY@1|root,32URC@2|Bacteria,4NST3@976|Bacteroidetes,1I448@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS2_k127_5229881_1	1358423.N180_07365	8.414e-157	509.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IRC7@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
CMS2_k127_5229881_3	1137281.D778_02127	3.817e-81	277.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,1HXNZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_523163_2	313596.RB2501_05635	1.194e-189	597.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
CMS2_k127_523163_1	313596.RB2501_05630	4.111e-293	909.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1HYDB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
CMS2_k127_523163_3	1121875.KB907553_gene67	1.732e-79	267.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1I17S@117743|Flavobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
CMS2_k127_523163_4	313596.RB2501_05620	1.051e-29	118.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I558@117743|Flavobacteriia	976|Bacteroidetes	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_523163_0	313596.RB2501_05610	2.227e-293	906.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia	976|Bacteroidetes	P	Chloride channel protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS2_k127_5243248_0	313596.RB2501_11282	3.212e-238	744.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia	976|Bacteroidetes	E	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_5243248_1	313596.RB2501_11277	3.018e-118	389.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,1HZQ9@117743|Flavobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS2_k127_5264315_0	1239962.C943_01005	0.0	1022.0	COG1262@1|root,COG1262@2|Bacteria,4NJRT@976|Bacteroidetes,47TU9@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_5264315_1	1121875.KB907546_gene2402	1.166e-181	574.0	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,1HZUR@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
CMS2_k127_5264315_4	1250232.JQNJ01000001_gene1032	2.932e-72	247.0	COG2930@1|root,COG2930@2|Bacteria,4NP71@976|Bacteroidetes,1I20I@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Family of	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
CMS2_k127_5264315_2	1122179.KB890469_gene491	7.055e-171	541.0	COG5285@1|root,COG5285@2|Bacteria,4NG3B@976|Bacteroidetes	976|Bacteroidetes	Q	PFAM Phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS2_k127_5264315_5	1250232.JQNJ01000001_gene2827	3.31e-45	171.0	2ATWF@1|root,31JFP@2|Bacteria,4NQ9K@976|Bacteroidetes,1I3SN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5264315_3	946077.W5A_06446	1.107e-100	336.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1I95J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5266845_2	313596.RB2501_15729	2.479e-102	337.0	COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,1HYJ6@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
CMS2_k127_5266845_8	1300350.DSW25_01510	2.575e-42	157.0	2ADBR@1|root,31316@2|Bacteria,1RD6U@1224|Proteobacteria,2U75P@28211|Alphaproteobacteria,3ZXDP@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2853
CMS2_k127_5266845_1	313596.RB2501_15739	9.932e-242	762.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,1HXR0@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
CMS2_k127_5266845_4	313596.RB2501_15744	1.974e-90	310.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,1HX5V@117743|Flavobacteriia	976|Bacteroidetes	HQ	Isochorismate synthase	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
CMS2_k127_5266845_7	1223410.KN050846_gene312	4.491e-43	161.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1I2BT@117743|Flavobacteriia	976|Bacteroidetes	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
CMS2_k127_5266845_5	313596.RB2501_15754	4.771e-68	237.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,1HZK4@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
CMS2_k127_5266845_6	313596.RB2501_15759	2.087e-67	233.0	COG1670@1|root,COG1670@2|Bacteria,4NM3W@976|Bacteroidetes,1I1MN@117743|Flavobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS2_k127_5266845_3	313596.RB2501_15764	1.641e-90	307.0	28KYI@1|root,2ZAE3@2|Bacteria,4NK21@976|Bacteroidetes,1HZ7T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5266845_0	313596.RB2501_15769	3.176e-289	892.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1HWQ0@117743|Flavobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS2_k127_5295096_4	313596.RB2501_00081	1.581e-165	524.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1HWMA@117743|Flavobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS2_k127_5295096_5	1137281.D778_00449	2.89e-127	440.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1HXPC@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS2_k127_5295096_8	313596.RB2501_00091	1.861e-63	220.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1I1AB@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CMS2_k127_5295096_1	886377.Murru_0543	2.087e-308	958.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1HZYU@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-fucosidase	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
CMS2_k127_5295096_0	313596.RB2501_00101	0.0	1093.0	COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,1HY3Y@117743|Flavobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
CMS2_k127_5295096_10	313596.RB2501_00116	2.608e-55	201.0	COG2020@1|root,COG2020@2|Bacteria,4NPVN@976|Bacteroidetes,1I2QK@117743|Flavobacteriia	976|Bacteroidetes	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS2_k127_5295096_7	313596.RB2501_00121	1.17e-74	261.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1I1CS@117743|Flavobacteriia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS2_k127_5295096_3	313596.RB2501_00126	4.055e-257	803.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HWMB@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS2_k127_5295096_6	313596.RB2501_00131	1.626e-124	403.0	COG1629@1|root,COG1629@2|Bacteria,4PKUT@976|Bacteroidetes,1IJFW@117743|Flavobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_5295096_2	313596.RB2501_00136	5.659e-283	878.0	COG0366@1|root,COG0366@2|Bacteria,4NGC8@976|Bacteroidetes,1HWR1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
CMS2_k127_5295096_9	1286632.P278_19990	4.284e-62	219.0	28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,1HYW5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5307742_4	313596.RB2501_05975	7.64e-21	99.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS2_k127_5307742_0	313596.RB2501_05980	1.396e-181	573.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1HYD7@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
CMS2_k127_5307742_3	313596.RB2501_05985	1.736e-31	124.0	COG1680@1|root,COG1680@2|Bacteria,4PKDG@976|Bacteroidetes,1HY39@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_5307742_2	313596.RB2501_05985	5.126e-149	481.0	COG1680@1|root,COG1680@2|Bacteria,4PKDG@976|Bacteroidetes,1HY39@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_5307742_1	313596.RB2501_05990	1.141e-169	537.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1HX0W@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS2_k127_5307742_5	1144343.PMI41_04580	8.58e-11	63.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,2U4TZ@28211|Alphaproteobacteria,43NTB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS2_k127_5309991_2	313596.RB2501_16029	1.897e-07	53.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS2_k127_5309991_0	313596.RB2501_16034	4.301e-123	400.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS2_k127_5309991_1	313596.RB2501_16039	8.536e-66	226.0	2E7SQ@1|root,3327W@2|Bacteria,4NUWY@976|Bacteroidetes,1I5CR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5315744_0	313596.RB2501_09280	1.227e-293	905.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
CMS2_k127_5315744_5	1380384.JADN01000006_gene2534	3.02e-21	95.0	COG0401@1|root,COG0401@2|Bacteria,4NUY1@976|Bacteroidetes,1I50E@117743|Flavobacteriia	976|Bacteroidetes	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
CMS2_k127_5315744_4	313596.RB2501_09285	2.241e-84	286.0	29Q6S@1|root,30B5S@2|Bacteria,4NIX7@976|Bacteroidetes,1I0R1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5315744_2	313596.RB2501_09290	1.252e-114	373.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1HXZT@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS2_k127_5315744_3	313596.RB2501_09295	1.462e-92	309.0	28P2C@1|root,2ZBYG@2|Bacteria,4NMEQ@976|Bacteroidetes,1I19G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5315744_1	313596.RB2501_09305	2.434e-157	501.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,1HZ3X@117743|Flavobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
CMS2_k127_5321552_5	1392498.JQLH01000001_gene2999	3.478e-38	150.0	COG2201@1|root,COG2201@2|Bacteria,4NSJ9@976|Bacteroidetes,1I4AV@117743|Flavobacteriia,2PHJX@252356|Maribacter	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_5321552_0	313596.RB2501_02280	2.257e-200	642.0	COG0642@1|root,COG2205@2|Bacteria,4PKI2@976|Bacteroidetes,1IJ9S@117743|Flavobacteriia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9
CMS2_k127_5321552_3	313596.RB2501_02275	3.071e-77	260.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1I1BI@117743|Flavobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS2_k127_5321552_1	313596.RB2501_02270	3.744e-160	509.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1HXXI@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS2_k127_5321552_2	313596.RB2501_02265	3.856e-95	315.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1I0RX@117743|Flavobacteriia	976|Bacteroidetes	M	serine threonine protein kinase	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
CMS2_k127_5321552_4	313596.RB2501_02260	8.928e-61	214.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_533770_2	1250005.PHEL85_0093	1.776e-112	381.0	COG2905@1|root,COG2905@2|Bacteria,4NDZ8@976|Bacteroidetes,1HWQU@117743|Flavobacteriia	976|Bacteroidetes	T	signal-transduction protein containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS2_k127_533770_0	313596.RB2501_13069	0.0	1205.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS2_k127_533770_1	313596.RB2501_13064	1.043e-313	970.0	COG4147@1|root,COG4147@2|Bacteria,4NHPT@976|Bacteroidetes,1HXQN@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS2_k127_533770_5	1121011.AUCB01000009_gene1914	3.471e-39	147.0	COG4327@1|root,COG4327@2|Bacteria,4NSV7@976|Bacteroidetes,1I3X5@117743|Flavobacteriia,23HJ7@178469|Arenibacter	976|Bacteroidetes	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
CMS2_k127_533770_3	1121875.KB907549_gene2097	5.765e-58	212.0	COG0589@1|root,COG0589@2|Bacteria,4NGD6@976|Bacteroidetes,1HYDX@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein UspA and related nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_533770_6	1286171.EAL2_c15250	1.135e-18	92.0	COG1371@1|root,COG1371@2|Bacteria,1VX66@1239|Firmicutes,252E3@186801|Clostridia	186801|Clostridia	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
CMS2_k127_533770_4	1121875.KB907549_gene1741	4.778e-55	195.0	COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,1HYNX@117743|Flavobacteriia	976|Bacteroidetes	S	RNA 2',3'-cyclic phosphate--5'-hydroxyl ligase	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS2_k127_53736_3	313596.RB2501_11147	2.469e-57	202.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,1I4DC@117743|Flavobacteriia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS2_k127_53736_2	313603.FB2170_01172	2.386e-65	225.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,2PHDS@252356|Maribacter	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
CMS2_k127_53736_0	313596.RB2501_11167	2.665e-183	578.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HY87@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS2_k127_53736_4	313596.RB2501_11172	1.506e-39	156.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1I2WA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
CMS2_k127_53736_1	313596.RB2501_11177	7.13e-86	289.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
CMS2_k127_53839_7	313596.RB2501_03070	0.0008195	42.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia	976|Bacteroidetes	V	Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_53839_2	313596.RB2501_03075	1.085e-120	390.0	COG2859@1|root,COG2859@2|Bacteria,4NI76@976|Bacteroidetes,1HZJF@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
CMS2_k127_53839_0	313596.RB2501_03080	2.188e-128	414.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,1HWW1@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS2_k127_53839_4	313596.RB2501_03085	2.094e-84	286.0	COG2968@1|root,COG2968@2|Bacteria,4NQGC@976|Bacteroidetes,1I2DK@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CMS2_k127_53839_1	1122176.KB903543_gene502	1.245e-127	415.0	COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,1IYJY@117747|Sphingobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS2_k127_53839_5	926562.Oweho_2535	4.314e-48	175.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia,2PBSD@246874|Cryomorphaceae	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_53839_3	1122179.KB890427_gene3857	7.398e-102	338.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1IV08@117747|Sphingobacteriia	976|Bacteroidetes	E	Arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS2_k127_53839_6	1121875.KB907547_gene2932	1.253e-41	154.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1I1R3@117743|Flavobacteriia	976|Bacteroidetes	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CMS2_k127_542761_1	504472.Slin_2066	4.837e-60	217.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,47P54@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF1624,DUF418
CMS2_k127_542761_0	1120965.AUBV01000004_gene1040	6.336e-101	336.0	COG1228@1|root,COG1228@2|Bacteria,4NGGD@976|Bacteroidetes,47R4K@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,SnoaL_2
CMS2_k127_5446217_2	1121875.KB907546_gene2739	3.871e-12	68.0	2DTB4@1|root,32UUV@2|Bacteria,4NSRC@976|Bacteroidetes,1I40G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5446217_1	313596.RB2501_00771	2.313e-95	325.0	COG0156@1|root,COG0156@2|Bacteria,4NKC1@976|Bacteroidetes,1HXSJ@117743|Flavobacteriia	976|Bacteroidetes	H	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS2_k127_5446217_0	313596.RB2501_00766	1.336e-96	317.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1HWNA@117743|Flavobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
CMS2_k127_5452904_0	1121875.KB907547_gene3455	2.327e-238	741.0	COG0471@1|root,COG0471@2|Bacteria,4NPCY@976|Bacteroidetes,1I05J@117743|Flavobacteriia	976|Bacteroidetes	P	2-oxoglutarate translocator	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
CMS2_k127_5452904_2	1286632.P278_00700	6.385e-55	196.0	2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CMS2_k127_5452904_1	1286632.P278_00540	4.288e-155	500.0	COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,1HWPK@117743|Flavobacteriia	976|Bacteroidetes	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_5452904_3	504487.JCM19302_3363	2.433e-44	170.0	2E3AK@1|root,32SYY@2|Bacteria,4NSTE@976|Bacteroidetes,1IIAV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5452904_6	1168034.FH5T_09910	8.652e-14	78.0	290G7@1|root,2ZN59@2|Bacteria,4P86U@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5452904_4	1121875.KB907547_gene3450	5.458e-19	93.0	COG4319@1|root,COG4319@2|Bacteria,4NTU3@976|Bacteroidetes	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS2_k127_5452904_5	1121875.KB907547_gene3125	7.712e-15	75.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_5468876_7	313596.RB2501_01795	8.342e-159	506.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1HX4E@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_5468876_2	313596.RB2501_01800	2.628e-226	708.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,4NG1I@976|Bacteroidetes,1HXHP@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS2_k127_5468876_8	313596.RB2501_01805	2.597e-125	408.0	COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,1HYAC@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
CMS2_k127_5468876_4	313596.RB2501_01810	2.165e-178	569.0	COG2035@1|root,COG2035@2|Bacteria,4NDU1@976|Bacteroidetes,1HYB3@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF368
CMS2_k127_5468876_10	313603.FB2170_09246	2.486e-83	283.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia,2PGQX@252356|Maribacter	976|Bacteroidetes	E	Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
CMS2_k127_5468876_0	313596.RB2501_01820	6.407e-290	916.0	COG1256@1|root,COG1256@2|Bacteria,4PKD3@976|Bacteroidetes,1HX3Q@117743|Flavobacteriia	976|Bacteroidetes	N	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
CMS2_k127_5468876_1	313596.RB2501_01825	1.489e-256	797.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS2_k127_5468876_3	313596.RB2501_01835	2.583e-224	708.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia	976|Bacteroidetes	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS2_k127_5468876_5	313596.RB2501_01845	4.367e-174	549.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS2_k127_5468876_15	886377.Murru_2207	8.944e-20	89.0	2E359@1|root,32Y58@2|Bacteria,4NV78@976|Bacteroidetes,1I50N@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
CMS2_k127_5468876_14	886377.Murru_2206	8.468e-30	118.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS2_k127_5468876_13	313596.RB2501_01855	8.302e-37	140.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1I3YG@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS2_k127_5468876_6	313596.RB2501_01860	2.712e-166	532.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1HWME@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS2_k127_5468876_11	313596.RB2501_01865	6.19e-49	177.0	COG2198@1|root,COG2198@2|Bacteria,4NVS6@976|Bacteroidetes,1I5MU@117743|Flavobacteriia	976|Bacteroidetes	T	(Hpt) domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
CMS2_k127_5468876_9	313596.RB2501_01870	1.959e-102	336.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1HX6X@117743|Flavobacteriia	976|Bacteroidetes	Q	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS2_k127_5468876_12	313596.RB2501_01875	4.251e-43	158.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS2_k127_549318_1	1121875.KB907549_gene1732	7.039e-42	157.0	2AXFQ@1|root,31PF8@2|Bacteria,4NQN3@976|Bacteroidetes,1I3BT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_549318_0	313596.RB2501_13114	1.355e-227	711.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1HXWF@117743|Flavobacteriia	976|Bacteroidetes	EGP	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS2_k127_5507106_1	313596.RB2501_03015	1.727e-190	601.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1HWZ7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS2_k127_5507106_6	1237149.C900_03631	2.081e-52	190.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,47XD5@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS2_k127_5507106_8	1121904.ARBP01000034_gene1816	5.27e-42	160.0	COG3324@1|root,COG3324@2|Bacteria,4NR6W@976|Bacteroidetes,47RGH@768503|Cytophagia	976|Bacteroidetes	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_5507106_7	313596.RB2501_03005	1.367e-42	162.0	COG3187@1|root,COG3187@2|Bacteria,4NR9M@976|Bacteroidetes,1I3FH@117743|Flavobacteriia	976|Bacteroidetes	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
CMS2_k127_5507106_9	1121898.Q766_02395	1.718e-18	95.0	2DSHF@1|root,33G4S@2|Bacteria,4NZ6J@976|Bacteroidetes,1I6RK@117743|Flavobacteriia,2NZC0@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5507106_0	313596.RB2501_03000	9.093e-212	661.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS2_k127_5507106_2	313596.RB2501_02995	1.19e-189	596.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
CMS2_k127_5507106_3	313596.RB2501_02985	3.125e-176	556.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1HWY7@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS2_k127_5507106_5	1392498.JQLH01000001_gene3366	1.263e-56	201.0	COG1416@1|root,COG1416@2|Bacteria,4NTE5@976|Bacteroidetes,1I9GD@117743|Flavobacteriia,2PINI@252356|Maribacter	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS2_k127_5507106_4	313596.RB2501_02980	4.611e-69	241.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_5553280_9	1121875.KB907546_gene2677	1.593e-09	59.0	COG2010@1|root,COG2010@2|Bacteria,4NX4D@976|Bacteroidetes,1I5CI@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5553280_3	313603.FB2170_12601	4.68e-106	353.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1I0TY@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5553280_2	1121875.KB907546_gene2674	1.82e-144	464.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,1I01K@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
CMS2_k127_5553280_1	866536.Belba_1302	4.117e-198	625.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS2_k127_5553280_5	866536.Belba_1301	6.238e-61	220.0	2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5553280_6	1121875.KB907546_gene2671	4.513e-45	166.0	COG2010@1|root,COG2010@2|Bacteria,4NV2A@976|Bacteroidetes,1I5FJ@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_5553280_4	1121875.KB907546_gene2670	1.154e-99	340.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Porphobil_deam,Shikimate_DH
CMS2_k127_5553280_7	1121875.KB907546_gene2669	1.17e-38	154.0	28PU4@1|root,2ZCF6@2|Bacteria,4NTXA@976|Bacteroidetes,1I497@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5553280_0	313596.RB2501_01535	0.0	2178.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NFBH@976|Bacteroidetes,1HZK7@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
CMS2_k127_5556399_5	313596.RB2501_10372	2.311e-127	409.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1HWVY@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS2_k127_5556399_1	313596.RB2501_10377	9.82e-188	591.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,1HYGW@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001,PHP
CMS2_k127_5556399_8	886377.Murru_0528	2.24e-18	87.0	2ENBC@1|root,33FYZ@2|Bacteria,4NY4C@976|Bacteroidetes,1I70M@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5556399_3	313596.RB2501_10387	2.47e-148	474.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1HXM5@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS2_k127_5556399_0	1250232.JQNJ01000001_gene430	0.0	1065.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia	976|Bacteroidetes	T	gtp-binding protein typa	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_5556399_4	313596.RB2501_10397	3.249e-139	445.0	COG1940@1|root,COG1940@2|Bacteria,4NFNR@976|Bacteroidetes,1HZGY@117743|Flavobacteriia	976|Bacteroidetes	GK	Transcriptional regulator sugar kinase	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS2_k127_5556399_7	1121875.KB907546_gene2448	4.621e-37	143.0	COG0494@1|root,COG0494@2|Bacteria,4NQHG@976|Bacteroidetes,1I32J@117743|Flavobacteriia	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_5556399_2	313596.RB2501_10402	5.357e-181	573.0	COG0477@1|root,COG2814@2|Bacteria,4NHGU@976|Bacteroidetes,1I0MN@117743|Flavobacteriia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS2_k127_5556399_6	313596.RB2501_10407	9.529e-40	148.0	COG1216@1|root,COG1216@2|Bacteria,4NI4Q@976|Bacteroidetes,1HXTR@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5565655_0	313596.RB2501_09060	1.108e-170	541.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,1HXRG@117743|Flavobacteriia	976|Bacteroidetes	U	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS2_k127_5565655_2	1121887.AUDK01000016_gene1851	6.853e-34	137.0	2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,1IERS@117743|Flavobacteriia,2NZA8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1705
CMS2_k127_5565655_1	313603.FB2170_13056	3.742e-42	158.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,1I2DE@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Fn3_assoc,Metallophos,PA14
CMS2_k127_5577098_0	1121890.AUDO01000004_gene2087	1.94e-175	591.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia,2NUQZ@237|Flavobacterium	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
CMS2_k127_5577098_1	616991.JPOO01000001_gene4473	2.705e-67	231.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS2_k127_5577098_2	313596.RB2501_09615	1.052e-13	78.0	29AVZ@1|root,2ZXV4@2|Bacteria,4P6S1@976|Bacteroidetes,1IB4R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5585106_1	313603.FB2170_02590	2.459e-132	430.0	COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,1HYHT@117743|Flavobacteriia,2PG0K@252356|Maribacter	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5585106_5	313596.RB2501_09795	1.086e-69	245.0	290I6@1|root,2ZN71@2|Bacteria,4NM5S@976|Bacteroidetes,1I19E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5585106_0	313596.RB2501_09800	2.817e-229	714.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1HXHG@117743|Flavobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS2_k127_5585106_6	911045.PSE_2387	3.644e-19	89.0	COG1226@1|root,302MR@2|Bacteria,1N49G@1224|Proteobacteria	1224|Proteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
CMS2_k127_5585106_3	313596.RB2501_09805	6.18e-99	332.0	COG0705@1|root,COG4765@1|root,COG0705@2|Bacteria,COG4765@2|Bacteria,4NGT3@976|Bacteroidetes,1HXF0@117743|Flavobacteriia	976|Bacteroidetes	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_5585106_2	1250232.JQNJ01000001_gene613	6.704e-102	340.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1HX8Z@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS2_k127_5585106_4	313603.FB2170_02560	2.946e-98	327.0	COG0526@1|root,COG0526@2|Bacteria,4PMBW@976|Bacteroidetes,1IJR4@117743|Flavobacteriia,2PGKV@252356|Maribacter	976|Bacteroidetes	CO	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS2_k127_5597348_2	1392488.JHZY01000004_gene1948	2.296e-28	118.0	COG4148@1|root,COG4148@2|Bacteria,4NVZD@976|Bacteroidetes,1I5X0@117743|Flavobacteriia,2XJPR@283735|Leeuwenhoekiella	976|Bacteroidetes	P	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
CMS2_k127_5597348_0	1121875.KB907549_gene1945	8.824e-110	359.0	COG4149@1|root,COG4149@2|Bacteria,4NIXK@976|Bacteroidetes,1I0Y9@117743|Flavobacteriia	976|Bacteroidetes	P	Molybdate ABC transporter permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS2_k127_5597348_1	1237149.C900_04291	7.319e-102	340.0	COG3842@1|root,COG3842@2|Bacteria,4NK56@976|Bacteroidetes,47MCQ@768503|Cytophagia	976|Bacteroidetes	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
CMS2_k127_5597348_3	313596.RB2501_05430	5.044e-09	58.0	COG3295@1|root,COG3295@2|Bacteria,4PMAA@976|Bacteroidetes,1IJPC@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
CMS2_k127_5613213_9	1121875.KB907550_gene948	4.529e-36	138.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS2_k127_5613213_6	313596.RB2501_03450	7.045e-123	397.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1HXX5@117743|Flavobacteriia	976|Bacteroidetes	T	response regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_5613213_0	313596.RB2501_03455	4.215e-275	859.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXUR@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,SNAP,TPR_12,TPR_16,TPR_7,TPR_8
CMS2_k127_5613213_3	313596.RB2501_03460	1.99e-146	475.0	COG2304@1|root,COG2304@2|Bacteria,4NEGD@976|Bacteroidetes,1HY72@117743|Flavobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS2_k127_5613213_2	313596.RB2501_03480	9.911e-199	625.0	COG2885@1|root,COG2885@2|Bacteria,4NH36@976|Bacteroidetes,1HWN0@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CMS2_k127_5613213_4	313596.RB2501_03485	1.976e-143	460.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
CMS2_k127_5613213_1	313596.RB2501_03495	7.907e-275	861.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
CMS2_k127_5613213_5	313596.RB2501_03500	2.678e-136	438.0	COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,1HXEP@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	mscS3	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
CMS2_k127_5613213_7	313596.RB2501_03505	1.159e-78	268.0	2A5Z8@1|root,30URD@2|Bacteria,4PFPQ@976|Bacteroidetes,1I6A8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5613213_8	313596.RB2501_03510	3.349e-51	184.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS2_k127_5654119_0	1250232.JQNJ01000001_gene2855	0.0	1299.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS2_k127_5654119_1	313596.RB2501_13494	3.171e-99	329.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1I2CE@117743|Flavobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS2_k127_5654119_2	1121875.KB907556_gene551	4.99e-20	89.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
CMS2_k127_5658393_4	1353276.JADR01000008_gene889	2.471e-40	152.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1HZ1U@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS2_k127_5658393_5	1121875.KB907551_gene965	1.322e-37	151.0	28KEX@1|root,2ZA14@2|Bacteria,4PAQ1@976|Bacteroidetes,1I8NT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5658393_6	313596.RB2501_12142	2.71e-18	94.0	2E3AK@1|root,32YA3@2|Bacteria,4NUYM@976|Bacteroidetes,1I52E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5658393_2	1223410.KN050846_gene2831	1.956e-57	209.0	2E3AK@1|root,30JD7@2|Bacteria,4NPG4@976|Bacteroidetes,1I2KR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5658393_0	1121875.KB907547_gene3471	3.241e-230	721.0	2C20F@1|root,32R9J@2|Bacteria,4P0SP@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CMS2_k127_5658393_1	1120965.AUBV01000004_gene1040	4.823e-66	230.0	COG1228@1|root,COG1228@2|Bacteria,4NGGD@976|Bacteroidetes,47R4K@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,SnoaL_2
CMS2_k127_5672468_0	313596.RB2501_03210	5.234e-242	752.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia	976|Bacteroidetes	F	nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CMS2_k127_5672468_1	1286632.P278_22070	1.7e-65	226.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1HX2F@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS2_k127_5676948_2	1239962.C943_00070	1.996e-67	233.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47KDB@768503|Cytophagia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
CMS2_k127_5676948_1	1120966.AUBU01000008_gene2373	2.626e-150	480.0	COG2159@1|root,COG2159@2|Bacteria,4NK6T@976|Bacteroidetes,47MSC@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS2_k127_5676948_0	1249997.JHZW01000003_gene3776	0.0	1684.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI8X@252356|Maribacter	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_5676948_3	1048983.EL17_11625	2.776e-62	217.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,47MUI@768503|Cytophagia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS2_k127_5685068_1	313596.RB2501_00141	1.424e-38	145.0	COG3324@1|root,COG3324@2|Bacteria,4NSBC@976|Bacteroidetes,1I3WN@117743|Flavobacteriia	976|Bacteroidetes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_5685068_0	1121875.KB907547_gene3460	3.263e-136	449.0	COG2067@1|root,COG2067@2|Bacteria,4NRUP@976|Bacteroidetes,1I6RT@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5685068_2	1286632.P278_19990	1.928e-27	117.0	28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,1HYW5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5689440_4	313603.FB2170_07574	5.089e-42	155.0	COG2146@1|root,COG2146@2|Bacteria,4NP7U@976|Bacteroidetes,1I3AW@117743|Flavobacteriia,2PHJN@252356|Maribacter	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5689440_0	313596.RB2501_08175	0.0	1172.0	COG4774@1|root,COG4774@2|Bacteria,4PKSG@976|Bacteroidetes,1IJEN@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS2_k127_5689440_1	313596.RB2501_08155	2.05e-312	980.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,1HYEB@117743|Flavobacteriia	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,DUF4301
CMS2_k127_5689440_5	313596.RB2501_08145	4.597e-38	145.0	COG0011@1|root,COG0011@2|Bacteria,4NSNT@976|Bacteroidetes,1I3X9@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM Protein of	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
CMS2_k127_5689440_3	313596.RB2501_08140	2.023e-100	330.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1HYHB@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
CMS2_k127_5689440_2	313596.RB2501_08135	3.802e-262	811.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1HWQ7@117743|Flavobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS2_k127_5753691_4	1392498.JQLH01000001_gene3641	7.921e-47	169.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia,2PH3A@252356|Maribacter	976|Bacteroidetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS2_k127_5753691_0	313596.RB2501_08315	0.0	1669.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
CMS2_k127_5753691_1	313596.RB2501_08305	5.714e-141	456.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1HXFX@117743|Flavobacteriia	976|Bacteroidetes	D	Required for cell division and gliding motility	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CMS2_k127_5753691_6	313596.RB2501_08300	2.23e-33	131.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1I3VV@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
CMS2_k127_5753691_2	313596.RB2501_08295	2.472e-120	391.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1HWSY@117743|Flavobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS2_k127_5753691_3	313596.RB2501_08290	1.527e-110	361.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
CMS2_k127_5753691_5	886377.Murru_1015	2.357e-36	141.0	COG0810@1|root,COG0810@2|Bacteria,4NN8A@976|Bacteroidetes,1I18J@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5805947_1	313596.RB2501_08570	0.0	1081.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_5805947_0	313596.RB2501_08575	0.0	1530.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
CMS2_k127_5805947_2	313596.RB2501_08580	7.834e-218	680.0	COG0446@1|root,COG0446@2|Bacteria,4P0D3@976|Bacteroidetes,1IJPG@117743|Flavobacteriia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CMS2_k127_5817493_2	313596.RB2501_11342	1.615e-82	276.0	COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes,1I7AI@117743|Flavobacteriia	976|Bacteroidetes	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
CMS2_k127_5817493_6	688270.Celal_0344	3.969e-43	162.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,1I340@117743|Flavobacteriia,1F9JA@104264|Cellulophaga	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS2_k127_5817493_1	143224.JQMD01000002_gene4175	3.601e-151	481.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1HWWP@117743|Flavobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS2_k127_5817493_0	1443665.JACA01000003_gene775	5.882e-191	602.0	COG1730@1|root,COG1730@2|Bacteria,4NHZT@976|Bacteroidetes,1HZM3@117743|Flavobacteriia	976|Bacteroidetes	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CMS2_k127_5817493_5	1121011.AUCB01000004_gene2826	1.616e-46	175.0	COG4659@1|root,COG4659@2|Bacteria,4NPUB@976|Bacteroidetes,1I2MB@117743|Flavobacteriia,23HDD@178469|Arenibacter	976|Bacteroidetes	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
CMS2_k127_5817493_4	886377.Murru_0359	1.083e-54	196.0	2CCRG@1|root,30F34@2|Bacteria,4NP6P@976|Bacteroidetes,1I2CY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5817493_3	313596.RB2501_11357	1.35e-65	225.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1HWYC@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS2_k127_5827841_6	1178825.ALIH01000011_gene28	1.044e-68	241.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1I19I@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
CMS2_k127_5827841_0	313596.RB2501_08955	4.041e-309	951.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1HX8K@117743|Flavobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS2_k127_5827841_8	313596.RB2501_08960	3.165e-49	176.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1I3WW@117743|Flavobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS2_k127_5827841_7	313596.RB2501_08965	1.994e-53	190.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,1I418@117743|Flavobacteriia	976|Bacteroidetes	U	Preprotein translocase	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS2_k127_5827841_4	313596.RB2501_08970	7.764e-124	403.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,1HZ4X@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5827841_5	313596.RB2501_08975	3.683e-80	271.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1I1XM@117743|Flavobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
CMS2_k127_5827841_2	313596.RB2501_08980	3.2e-218	683.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1HXHS@117743|Flavobacteriia	976|Bacteroidetes	K	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS2_k127_5827841_1	313596.RB2501_08985	2.005e-259	807.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS2_k127_5827841_3	313596.RB2501_08990	2.132e-185	587.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,1HYS1@117743|Flavobacteriia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS2_k127_5827841_9	1121875.KB907547_gene2980	9.647e-45	166.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_5861603_4	313596.RB2501_05750	3.19e-50	182.0	28KSE@1|root,2ZA9S@2|Bacteria,4NKV8@976|Bacteroidetes,1I1N7@117743|Flavobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_5861603_2	313596.RB2501_05740	1.196e-158	505.0	COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes,1HYV9@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_5861603_3	1249997.JHZW01000002_gene864	7.435e-61	213.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,1I4NU@117743|Flavobacteriia,2PHD2@252356|Maribacter	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CMS2_k127_5861603_0	313596.RB2501_05730	3.892e-210	659.0	COG0477@1|root,COG2814@2|Bacteria,4PKJD@976|Bacteroidetes,1IJAV@117743|Flavobacteriia	976|Bacteroidetes	EGP	Nucleoside H symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
CMS2_k127_5861603_1	313596.RB2501_05725	5.999e-197	616.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,1HYBZ@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Major facilitator superfamily MFS-1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_5906153_4	1004149.AFOE01000007_gene1459	8.447e-58	205.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1HYZ1@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
CMS2_k127_5906153_1	313596.RB2501_13184	8.735e-168	539.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,1HYXX@117743|Flavobacteriia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340,3.2.1.197	ko:K20885,ko:K21065	-	-	R11397,R11398,R11544	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS2_k127_5906153_2	313596.RB2501_13164	6.152e-133	428.0	COG1082@1|root,COG1082@2|Bacteria,4NFMD@976|Bacteroidetes,1HZAA@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_5906153_3	1121875.KB907555_gene355	2.079e-109	358.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1HYT7@117743|Flavobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_5906153_0	1121875.KB907555_gene354	0.0	1075.0	COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes,1HXAS@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
CMS2_k127_5906153_5	313596.RB2501_13154	5.573e-29	119.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CMS2_k127_5916960_0	313596.RB2501_08600	0.0	1279.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
CMS2_k127_5916960_1	313596.RB2501_08595	2.886e-29	118.0	COG0637@1|root,COG0637@2|Bacteria,4NEEH@976|Bacteroidetes,1HX4N@117743|Flavobacteriia	976|Bacteroidetes	S	beta-phosphoglucomutase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS2_k127_5925441_1	313596.RB2501_05340	2.715e-75	259.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,1I1J9@117743|Flavobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS2_k127_5925441_0	509635.N824_13235	3.567e-172	558.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CMS2_k127_5925576_1	313596.RB2501_16099	5.868e-256	790.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1HX45@117743|Flavobacteriia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS2_k127_5925576_9	313596.RB2501_16104	3.767e-59	208.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1I1Z5@117743|Flavobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS2_k127_5925576_5	313596.RB2501_16109	5.24e-106	348.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1HXGW@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS2_k127_5925576_7	143224.JQMD01000002_gene542	1.819e-83	282.0	COG0741@1|root,COG0741@2|Bacteria,4NMIF@976|Bacteroidetes,1I1GE@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan-binding protein LysM	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5925576_3	313596.RB2501_16119	1.576e-160	514.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1HWPX@117743|Flavobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS2_k127_5925576_8	1121012.AUKX01000041_gene3278	5.038e-66	230.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,1I27H@117743|Flavobacteriia,23FRB@178469|Arenibacter	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
CMS2_k127_5925576_4	313596.RB2501_16129	4.271e-109	358.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1HY3U@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS2_k127_5925576_2	313596.RB2501_16134	1.261e-229	717.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1HXT7@117743|Flavobacteriia	976|Bacteroidetes	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
CMS2_k127_5925576_0	313596.RB2501_16139	1.466e-259	806.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS2_k127_5925576_6	313596.RB2501_16144	1.14e-87	293.0	28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,1I3WF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5925576_10	1406840.Q763_05665	8.274e-19	89.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1HXFN@117743|Flavobacteriia,2NSVS@237|Flavobacterium	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS2_k127_596182_0	313596.RB2501_15059	7.667e-196	621.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	sad	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_596182_1	313596.RB2501_15049	2.508e-55	195.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
CMS2_k127_5963096_2	313596.RB2501_11312	1.93e-82	274.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,1HXU3@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_5963096_3	1408473.JHXO01000005_gene1608	3.591e-75	259.0	COG0412@1|root,COG0412@2|Bacteria,4NKMA@976|Bacteroidetes,2FTW8@200643|Bacteroidia	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS2_k127_5963096_6	1288963.ADIS_0316	2.091e-52	192.0	COG4430@1|root,COG4430@2|Bacteria,4NKNI@976|Bacteroidetes,47RFJ@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
CMS2_k127_5963096_0	313596.RB2501_11322	1.372e-204	646.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1HWV8@117743|Flavobacteriia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_5963096_7	313596.RB2501_11327	5.365e-42	160.0	2E8QI@1|root,3331H@2|Bacteria,4NX0G@976|Bacteroidetes,1I545@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5963096_1	313596.RB2501_11332	3.073e-166	530.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS2_k127_5963096_5	313596.RB2501_11337	8.8e-55	199.0	2E6PT@1|root,331A4@2|Bacteria,4NVEZ@976|Bacteroidetes,1I5S3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_5963096_4	313596.RB2501_11342	4.14e-56	198.0	COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes,1I7AI@117743|Flavobacteriia	976|Bacteroidetes	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
CMS2_k127_597328_5	313596.RB2501_14784	6.142e-05	47.0	COG0793@1|root,COG4976@1|root,COG0793@2|Bacteria,COG4976@2|Bacteria,4NIS9@976|Bacteroidetes,1HZR4@117743|Flavobacteriia	976|Bacteroidetes	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS2_k127_597328_4	485917.Phep_0279	5.505e-06	56.0	2E5XB@1|root,330M9@2|Bacteria,4NW0P@976|Bacteroidetes,1IU5F@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4251)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4251
CMS2_k127_597328_3	555500.I215_03168	1.238e-11	72.0	2E5XB@1|root,32TRA@2|Bacteria,4NSFZ@976|Bacteroidetes,1I41W@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4251)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4251
CMS2_k127_597328_1	1237149.C900_04106	1.296e-41	155.0	COG0640@1|root,COG0640@2|Bacteria,4NQ33@976|Bacteroidetes,47QAK@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS2_k127_597328_0	313596.RB2501_14804	1.252e-196	616.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1I911@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_5975741_2	313596.RB2501_09305	6.84e-70	249.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,1HZ3X@117743|Flavobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
CMS2_k127_5975741_1	313596.RB2501_09310	1.717e-95	316.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1HWSB@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS2_k127_5975741_0	411154.GFO_2922	3.26e-281	878.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_5982399_1	313596.RB2501_07500	4.335e-191	613.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
CMS2_k127_5982399_0	313596.RB2501_07495	8.48e-229	711.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_5982678_0	313596.RB2501_05320	5.441e-102	345.0	COG1680@1|root,COG1680@2|Bacteria,4NF42@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_5982678_1	1392488.JHZY01000002_gene382	1.696e-88	297.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1HX81@117743|Flavobacteriia,2XIBC@283735|Leeuwenhoekiella	976|Bacteroidetes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS2_k127_5987078_0	313596.RB2501_14494	4.295e-182	573.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS2_k127_5987078_1	313596.RB2501_14499	3.786e-147	473.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZEJ@117743|Flavobacteriia	976|Bacteroidetes	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CMS2_k127_5987078_2	886377.Murru_3228	5.772e-40	154.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1HX8T@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
CMS2_k127_6001497_14	313596.RB2501_14749	8.352e-38	145.0	COG1544@1|root,COG1544@2|Bacteria,4NS9B@976|Bacteroidetes,1I4CZ@117743|Flavobacteriia	976|Bacteroidetes	J	Sigma 54 modulation protein S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS2_k127_6001497_1	313596.RB2501_14694	0.0	1080.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS2_k127_6001497_5	313596.RB2501_14689	3.995e-182	572.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,1HWU5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CMS2_k127_6001497_13	1122225.AULQ01000001_gene1860	5.206e-47	170.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1I2UU@117743|Flavobacteriia	976|Bacteroidetes	J	Translation initiation factor	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
CMS2_k127_6001497_6	313596.RB2501_14679	4.268e-172	543.0	2DBAY@1|root,2Z84S@2|Bacteria,4NGXD@976|Bacteroidetes,1HXHD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
CMS2_k127_6001497_7	1121875.KB907548_gene1440	1.405e-118	387.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1HYDH@117743|Flavobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS2_k127_6001497_8	313603.FB2170_11906	4.638e-115	376.0	COG0715@1|root,COG0715@2|Bacteria,4NETN@976|Bacteroidetes,1HYVJ@117743|Flavobacteriia,2PH62@252356|Maribacter	976|Bacteroidetes	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
CMS2_k127_6001497_10	313596.RB2501_14664	3.574e-110	359.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS2_k127_6001497_17	251221.35211431	5.904e-06	56.0	2EAFX@1|root,334J9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6001497_2	313596.RB2501_14659	0.0	1011.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1HX0J@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
CMS2_k127_6001497_12	313596.RB2501_14654	1.669e-61	214.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia	976|Bacteroidetes	S	Thiol-disulfide oxidoreductase	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS2_k127_6001497_3	313596.RB2501_14634	1.136e-237	740.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS2_k127_6001497_4	313596.RB2501_14629	2.046e-184	581.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS2_k127_6001497_9	1004149.AFOE01000004_gene2372	2.181e-111	366.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1HY0C@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
CMS2_k127_6001497_0	313596.RB2501_14619	0.0	1474.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia	976|Bacteroidetes	C	FAD linked	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
CMS2_k127_6001497_11	313596.RB2501_14614	1.267e-89	297.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1I1YP@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6001497_15	313596.RB2501_14609	1.586e-15	79.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CMS2_k127_6004670_1	313596.RB2501_03715	1.261e-276	857.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
CMS2_k127_6004670_2	313596.RB2501_03720	1.527e-254	790.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
CMS2_k127_6004670_3	313596.RB2501_03725	2.882e-46	170.0	2C8TJ@1|root,32RMV@2|Bacteria,4NSAA@976|Bacteroidetes,1I54A@117743|Flavobacteriia	976|Bacteroidetes	S	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_6004670_0	313596.RB2501_03730	4.63e-311	956.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
CMS2_k127_6010010_0	313596.RB2501_00496	5.825e-263	814.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HWVV@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
CMS2_k127_604842_1	313596.RB2501_03270	6.365e-121	391.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS2_k127_604842_0	313596.RB2501_03265	0.0	1504.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS2_k127_604842_2	313596.RB2501_03260	4.206e-111	366.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1HXE0@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS2_k127_604842_4	313596.RB2501_03255	1.781e-71	245.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1I1AX@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS2_k127_604842_3	313596.RB2501_03250	1.984e-103	346.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1HX4S@117743|Flavobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CMS2_k127_604842_5	313596.RB2501_03245	1.105e-32	128.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
CMS2_k127_6059708_14	313596.RB2501_05810	2.864e-26	108.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia	976|Bacteroidetes	U	UPF0056 membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS2_k127_6059708_15	616991.JPOO01000003_gene2678	1.193e-17	85.0	2C4ZA@1|root,30ZR1@2|Bacteria,4PE1D@976|Bacteroidetes,1IEF7@117743|Flavobacteriia,23HP3@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6059708_0	313596.RB2501_05820	1.323e-281	871.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1HXSR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS2_k127_6059708_11	1121012.AUKX01000008_gene106	1.922e-76	258.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia,23H9Y@178469|Arenibacter	976|Bacteroidetes	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
CMS2_k127_6059708_12	313596.RB2501_05830	2.503e-76	260.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS2_k127_6059708_7	313596.RB2501_05835	5.437e-124	400.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,1HYUI@117743|Flavobacteriia	976|Bacteroidetes	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
CMS2_k127_6059708_13	313596.RB2501_05840	1.784e-74	251.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
CMS2_k127_6059708_8	313596.RB2501_05845	3.124e-122	395.0	COG0204@1|root,COG0204@2|Bacteria,4NHC8@976|Bacteroidetes,1HY24@117743|Flavobacteriia	976|Bacteroidetes	I	acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_6059708_9	313596.RB2501_05850	3.717e-103	338.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1HX55@117743|Flavobacteriia	976|Bacteroidetes	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
CMS2_k127_6059708_1	313596.RB2501_05855	1.11e-279	863.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1HXRM@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_6059708_4	313596.RB2501_05860	3.437e-171	543.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1HYJS@117743|Flavobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS2_k127_6059708_2	313596.RB2501_05865	6.042e-259	807.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NH2P@976|Bacteroidetes,1HXG7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6059708_6	313596.RB2501_05870	2.582e-128	417.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS2_k127_6059708_3	313596.RB2501_05875	1.123e-250	780.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1HXA7@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_6059708_10	313596.RB2501_05880	6.118e-82	276.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS2_k127_6059708_5	313596.RB2501_05885	3.784e-165	531.0	COG1114@1|root,COG1114@2|Bacteria,4NHB9@976|Bacteroidetes,1HXUK@117743|Flavobacteriia	976|Bacteroidetes	E	branched-chain amino acid transport system II carrier protein	brnQ	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
CMS2_k127_6065114_4	313596.RB2501_11857	4.18e-86	289.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,1HYMG@117743|Flavobacteriia	976|Bacteroidetes	E	Glycine D-amino acid	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
CMS2_k127_6065114_2	313596.RB2501_11852	3.026e-129	418.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,1HWT4@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
CMS2_k127_6065114_0	313596.RB2501_11847	3.806e-246	767.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS2_k127_6065114_1	313596.RB2501_11842	1.145e-150	479.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1HXBH@117743|Flavobacteriia	976|Bacteroidetes	I	Phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
CMS2_k127_6065114_3	313596.RB2501_11837	5.007e-88	293.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1I1A9@117743|Flavobacteriia	976|Bacteroidetes	I	hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
CMS2_k127_6074599_1	1121875.KB907548_gene1528	2.654e-185	592.0	COG2355@1|root,COG2355@2|Bacteria,4NI3V@976|Bacteroidetes,1I0XS@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
CMS2_k127_6074599_4	313596.RB2501_14884	2.631e-101	336.0	COG1028@1|root,COG1028@2|Bacteria,4NMH8@976|Bacteroidetes,1I4HV@117743|Flavobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_6074599_7	313596.RB2501_14879	7.504e-29	116.0	2E52B@1|root,32ZVI@2|Bacteria,4NUUC@976|Bacteroidetes,1I5DV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6074599_6	313596.RB2501_14869	3.064e-61	218.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1I2YF@117743|Flavobacteriia	976|Bacteroidetes	O	Peroxiredoxin	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
CMS2_k127_6074599_2	313596.RB2501_14844	3.348e-142	457.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1HWKK@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_6074599_0	313596.RB2501_14839	0.0	1183.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_6074599_3	313596.RB2501_14824	5.628e-108	359.0	COG3401@1|root,COG3401@2|Bacteria,4NKNR@976|Bacteroidetes,1I02K@117743|Flavobacteriia	976|Bacteroidetes	S	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6074599_5	143224.JQMD01000002_gene882	3.629e-85	286.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1HYQE@117743|Flavobacteriia	976|Bacteroidetes	G	L-sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS2_k127_610003_1	1121875.KB907547_gene2936	7.24e-17	81.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
CMS2_k127_610003_0	1250232.JQNJ01000001_gene2191	4.786e-256	795.0	COG2936@1|root,COG2936@2|Bacteria,4NHGT@976|Bacteroidetes,1HYGE@117743|Flavobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
CMS2_k127_6107417_11	391603.FBALC1_11552	1.144e-33	134.0	COG2972@1|root,COG2972@2|Bacteria,4NIVE@976|Bacteroidetes,1HYCB@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS2_k127_6107417_10	1336803.PHEL49_1006	8.506e-68	237.0	COG3279@1|root,COG3279@2|Bacteria,4NFZT@976|Bacteroidetes,1HYGC@117743|Flavobacteriia,3VXGM@52959|Polaribacter	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS2_k127_6107417_6	1239962.C943_04290	3.402e-160	511.0	COG0657@1|root,COG0657@2|Bacteria,4PKKH@976|Bacteroidetes,47P2Y@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS2_k127_6107417_2	313596.RB2501_09400	1.736e-237	743.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,1HY2P@117743|Flavobacteriia	976|Bacteroidetes	P	arylsulfatase a	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CMS2_k127_6107417_5	313596.RB2501_09395	8.573e-179	567.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CMS2_k127_6107417_7	313596.RB2501_09390	1.122e-129	420.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1HX6B@117743|Flavobacteriia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS2_k127_6107417_9	313596.RB2501_09385	6.412e-68	233.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS2_k127_6107417_8	313596.RB2501_09380	9.084e-127	408.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1HXWI@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_6107417_1	313596.RB2501_09375	1.538e-241	751.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS2_k127_6107417_3	313596.RB2501_09370	2.506e-235	734.0	COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes,1HXP5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_6107417_4	313596.RB2501_09365	3.793e-214	668.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS2_k127_6107417_0	313596.RB2501_09360	0.0	1501.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS2_k127_61173_2	1408473.JHXO01000005_gene1790	8.045e-75	255.0	COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes,2FYGT@200643|Bacteroidia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS2_k127_61173_0	388413.ALPR1_08898	1.344e-181	577.0	COG2851@1|root,COG2851@2|Bacteria,4NHKQ@976|Bacteroidetes,47MP2@768503|Cytophagia	976|Bacteroidetes	C	Na+/H+ antiporter family	-	-	-	ko:K03300	-	-	-	-	ko00000	2.A.11	-	-	CitMHS
CMS2_k127_61173_1	388413.ALPR1_08903	8.553e-144	473.0	COG3185@1|root,COG3185@2|Bacteria,4NGFD@976|Bacteroidetes,47N1N@768503|Cytophagia	976|Bacteroidetes	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
CMS2_k127_6123570_1	1121875.KB907549_gene2044	1.57e-126	406.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS2_k127_6123570_0	313596.RB2501_12377	4.102e-251	778.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1HXI3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6123570_2	313596.RB2501_12382	9.227e-116	378.0	COG0561@1|root,COG0561@2|Bacteria,4NG7K@976|Bacteroidetes,1HY6R@117743|Flavobacteriia	976|Bacteroidetes	S	of the HAD superfamily	supH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS2_k127_6123570_4	313596.RB2501_12387	2.44e-64	223.0	COG0432@1|root,COG0432@2|Bacteria,4NNMN@976|Bacteroidetes,1I21B@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS2_k127_6123570_5	1121011.AUCB01000032_gene2037	2.439e-63	218.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia,23HB7@178469|Arenibacter	976|Bacteroidetes	J	Ribosomal protein L20	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS2_k127_6123570_6	555500.I215_14119	6.286e-24	102.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1I52P@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS2_k127_6123570_3	1392490.JHZX01000001_gene426	5.021e-84	280.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS2_k127_6142136_2	313596.RB2501_06830	2.257e-75	256.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS2_k127_6142136_1	1121875.KB907551_gene1069	1.33e-147	475.0	COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,1HYBV@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
CMS2_k127_6142136_0	313596.RB2501_06825	0.0	1112.0	COG0419@1|root,COG0419@2|Bacteria,4PMAD@976|Bacteroidetes,1IJPD@117743|Flavobacteriia	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6142444_2	313596.RB2501_11042	7.803e-208	650.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS2_k127_6142444_0	313596.RB2501_11037	0.0	1267.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
CMS2_k127_6142444_1	313596.RB2501_11032	1.086e-215	670.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1HXPA@117743|Flavobacteriia	976|Bacteroidetes	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS2_k127_6142444_4	143224.JQMD01000002_gene4113	7.848e-125	407.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1HXR1@117743|Flavobacteriia	976|Bacteroidetes	P	Ca2 Na antiporter	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS2_k127_6142444_6	313596.RB2501_11017	2.702e-60	210.0	COG3682@1|root,COG3682@2|Bacteria,4NT4V@976|Bacteroidetes,1I2YY@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS2_k127_6142444_3	313596.RB2501_11012	1.39e-180	584.0	COG1629@1|root,COG4219@1|root,COG4219@2|Bacteria,COG4771@2|Bacteria,4NDWS@976|Bacteroidetes,1HX6K@117743|Flavobacteriia	976|Bacteroidetes	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Plug
CMS2_k127_6142444_7	313596.RB2501_10997	1.041e-19	90.0	2EMAM@1|root,33EZM@2|Bacteria,4NXGW@976|Bacteroidetes,1I693@117743|Flavobacteriia	976|Bacteroidetes	S	SsrA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6142444_5	313596.RB2501_10992	2.035e-86	289.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1I29Z@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS2_k127_6150789_3	616991.JPOO01000003_gene1492	9.163e-42	161.0	COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,1HYHT@117743|Flavobacteriia,23GXX@178469|Arenibacter	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6150789_1	1121875.KB907546_gene2292	1.091e-59	212.0	2E7WJ@1|root,302JY@2|Bacteria,4NNPN@976|Bacteroidetes,1I21E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6150789_0	1121012.AUKX01000021_gene1709	1.444e-88	299.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1I188@117743|Flavobacteriia,23H3U@178469|Arenibacter	976|Bacteroidetes	S	HAD-hyrolase-like	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS2_k127_6150789_2	616991.JPOO01000003_gene1495	1.433e-53	192.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia,23FX0@178469|Arenibacter	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6162453_5	313596.RB2501_06640	2.046e-18	87.0	28JCX@1|root,2Z97G@2|Bacteria,4NII8@976|Bacteroidetes,1I0YE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6162453_4	313596.RB2501_06645	1.392e-29	119.0	2E670@1|root,330VJ@2|Bacteria,4NV1K@976|Bacteroidetes,1I58V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6162453_1	313596.RB2501_06650	6.795e-203	639.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1HXGE@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS2_k127_6162453_2	1250232.JQNJ01000001_gene1289	2.211e-185	582.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS2_k127_6162453_0	313596.RB2501_06665	3.355e-223	698.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1HXT6@117743|Flavobacteriia	976|Bacteroidetes	M	sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
CMS2_k127_6162453_3	1189619.pgond44_13422	1.535e-55	196.0	COG1922@1|root,COG1922@2|Bacteria,4NJGT@976|Bacteroidetes,1I0I3@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
CMS2_k127_6184754_2	1123073.KB899241_gene1898	1.998e-10	61.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,1X4F1@135614|Xanthomonadales	1236|Gammaproteobacteria	E	GMC oxidoreductase	neoG	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CMS2_k127_6184754_0	1454007.JAUG01000047_gene512	2.788e-130	425.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_6184754_1	1267211.KI669560_gene254	1.888e-26	114.0	2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,1ISA1@117747|Sphingobacteriia	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_620096_0	1250232.JQNJ01000001_gene498	0.0	1843.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS2_k127_620096_2	1250232.JQNJ01000001_gene1716	1.364e-14	78.0	2DCZP@1|root,2ZFY1@2|Bacteria,4PQ12@976|Bacteroidetes,1IKY7@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein S21	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S21
CMS2_k127_620096_1	1123277.KB893211_gene4414	6.227e-164	518.0	COG1082@1|root,COG1082@2|Bacteria,4NK9X@976|Bacteroidetes,47KBS@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS2_k127_620241_2	313596.RB2501_13724	4.352e-111	372.0	COG3204@1|root,COG3204@2|Bacteria,4NJBU@976|Bacteroidetes,1HZA5@117743|Flavobacteriia	976|Bacteroidetes	L	pilus organization	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_620241_6	313596.RB2501_13719	1.574e-65	231.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS2_k127_620241_4	313596.RB2501_13714	4.954e-98	324.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1HX5Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	with different specificities (Related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_620241_1	313596.RB2501_13709	8.641e-200	630.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1HXRR@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS2_k127_620241_0	313603.FB2170_10424	2.223e-251	781.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia,2PGP8@252356|Maribacter	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_620241_7	313596.RB2501_13689	9.719e-45	166.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,1I5MP@117743|Flavobacteriia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
CMS2_k127_620241_5	313596.RB2501_13684	1.221e-73	250.0	COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,1I32P@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_620241_3	313596.RB2501_13679	2.54e-101	337.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1HXX4@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS2_k127_6227338_7	616991.JPOO01000003_gene1441	8.741e-12	69.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1HX0R@117743|Flavobacteriia,23GHH@178469|Arenibacter	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS2_k127_6227338_4	313596.RB2501_10020	9.897e-153	486.0	COG1834@1|root,COG1834@2|Bacteria,4NEUJ@976|Bacteroidetes,1HWNG@117743|Flavobacteriia	976|Bacteroidetes	E	Cytochrome C biogenesis protein CcmF	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS2_k127_6227338_0	313596.RB2501_10015	5.303e-250	775.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1HWVX@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS2_k127_6227338_2	313596.RB2501_10010	1.37e-245	767.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1HZ60@117743|Flavobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS2_k127_6227338_1	313596.RB2501_10005	1.105e-249	775.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1HWRR@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS2_k127_6227338_3	313596.RB2501_09995	9.874e-219	683.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1HXZ3@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS2_k127_6227338_5	313596.RB2501_09990	2.093e-77	264.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia	976|Bacteroidetes	J	ribosomal protein l17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS2_k127_6227338_6	313596.RB2501_09985	1.306e-25	105.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS2_k127_6243514_2	1121875.KB907547_gene3442	2.436e-105	349.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,1I9UW@117743|Flavobacteriia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS2_k127_6243514_3	1121875.KB907547_gene3443	1.351e-49	180.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
CMS2_k127_6243514_0	388413.ALPR1_16144	5.024e-261	811.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,47JRY@768503|Cytophagia	976|Bacteroidetes	E	PFAM Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CMS2_k127_6243514_1	1239962.C943_04615	5.444e-123	410.0	COG4287@1|root,COG4287@2|Bacteria,4NI0U@976|Bacteroidetes,47KB9@768503|Cytophagia	976|Bacteroidetes	S	PhoPQ-activated pathogenicity-related protein	-	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
CMS2_k127_6251928_0	1121875.KB907553_gene125	3.108e-181	574.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1HXUV@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS2_k127_6252520_0	1121875.KB907549_gene1766	1.482e-251	783.0	COG2072@1|root,COG2072@2|Bacteria,4NGC0@976|Bacteroidetes	976|Bacteroidetes	P	flavoprotein involved in K transport	-	-	1.14.13.148	ko:K18277	ko00680,map00680	-	R05623	RC00058	ko00000,ko00001,ko01000	-	-	-	FMO-like
CMS2_k127_6252520_1	1121875.KB907548_gene1609	7.627e-223	703.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,1HZSK@117743|Flavobacteriia	976|Bacteroidetes	P	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_6252520_3	1121875.KB907548_gene1612	1.767e-67	237.0	COG0596@1|root,COG0596@2|Bacteria,4PNQK@976|Bacteroidetes,1IKAD@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6252520_2	1121875.KB907547_gene3433	1.186e-191	606.0	COG3118@1|root,COG3118@2|Bacteria,4PMAJ@976|Bacteroidetes,1IJPK@117743|Flavobacteriia	976|Bacteroidetes	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS2_k127_6292354_9	313596.RB2501_08435	6.218e-16	77.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1I3YF@117743|Flavobacteriia	976|Bacteroidetes	O	Nitrogen fixation protein NifU	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
CMS2_k127_6292354_2	313596.RB2501_08440	3.553e-197	617.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_6292354_7	313596.RB2501_08445	1.172e-48	175.0	COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,1I32H@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin	thcC	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS2_k127_6292354_6	313603.FB2170_07989	6.483e-49	177.0	2EDMN@1|root,337HG@2|Bacteria,4NWVI@976|Bacteroidetes,1I9SP@117743|Flavobacteriia	976|Bacteroidetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS2_k127_6292354_0	313603.FB2170_07984	0.0	1953.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1HXEG@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS2_k127_6292354_5	1121875.KB907547_gene3137	2.524e-62	215.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	fdx1	-	-	ko:K03522,ko:K05337	-	-	-	-	ko00000,ko04147	-	-	-	Fer4,Fer4_7
CMS2_k127_6292354_1	313603.FB2170_07974	0.0	1023.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1I09M@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS2_k127_6292354_3	313603.FB2170_07969	1.933e-195	612.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1I0PA@117743|Flavobacteriia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS2_k127_6292354_4	313603.FB2170_10161	1.579e-91	303.0	COG4657@1|root,COG4657@2|Bacteria,4PPXA@976|Bacteroidetes,1I9U6@117743|Flavobacteriia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_6292354_8	313603.FB2170_10156	3.199e-33	129.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_6303854_4	313596.RB2501_14504	3.632e-53	187.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1HX8T@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
CMS2_k127_6303854_1	313596.RB2501_14509	1.687e-168	533.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1HY7B@117743|Flavobacteriia	976|Bacteroidetes	N	flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS2_k127_6303854_0	313596.RB2501_14514	3.748e-169	542.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1HXBB@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS2_k127_6303854_3	313596.RB2501_14519	8.106e-71	242.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia	976|Bacteroidetes	V	Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
CMS2_k127_6303854_2	313596.RB2501_14524	1.382e-149	477.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1HXIE@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS2_k127_6306166_0	313596.RB2501_09845	7.589e-204	636.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1HY04@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_6306166_4	1197477.IA57_08260	1.873e-53	192.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1I2VK@117743|Flavobacteriia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS2_k127_6306166_2	867900.Celly_2146	8.11e-117	377.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1HXHF@117743|Flavobacteriia,1F814@104264|Cellulophaga	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS2_k127_6306166_3	313596.RB2501_09860	8.925e-107	349.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,1HXZA@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS2_k127_6306166_7	1348583.ATLH01000005_gene785	8.673e-45	163.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,1I45R@117743|Flavobacteriia,1F9HZ@104264|Cellulophaga	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS2_k127_6306166_1	313596.RB2501_09870	1.178e-162	513.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1HXDV@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS2_k127_6306166_5	313596.RB2501_09875	2.175e-53	188.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS2_k127_6306166_6	980584.AFPB01000138_gene2702	1.172e-48	175.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1I18F@117743|Flavobacteriia,406B8@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	J	Ribosomal protein L22p/L17e	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS2_k127_632762_8	1336803.PHEL49_0732	6.612e-53	192.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes,1IMXZ@117743|Flavobacteriia,3VX5W@52959|Polaribacter	976|Bacteroidetes	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS2_k127_632762_2	1336803.PHEL49_0732	4.926e-80	273.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes,1IMXZ@117743|Flavobacteriia,3VX5W@52959|Polaribacter	976|Bacteroidetes	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS2_k127_632762_9	926559.JoomaDRAFT_0567	2.836e-51	189.0	COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes,1HYNR@117743|Flavobacteriia	976|Bacteroidetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_632762_7	313596.RB2501_13044	1.951e-54	197.0	COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes,1HYNR@117743|Flavobacteriia	976|Bacteroidetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_632762_10	313596.RB2501_13054	3.184e-44	169.0	COG3467@1|root,COG3467@2|Bacteria,4NQFR@976|Bacteroidetes,1I2TN@117743|Flavobacteriia	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS2_k127_632762_0	313596.RB2501_13039	1.093e-136	443.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1HYV8@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS2_k127_632762_1	1121011.AUCB01000022_gene3682	2.038e-114	379.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,4NK8R@976|Bacteroidetes,1I0Y1@117743|Flavobacteriia,23FP3@178469|Arenibacter	976|Bacteroidetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
CMS2_k127_632762_5	1121875.KB907549_gene1743	1.897e-71	249.0	COG1073@1|root,COG1073@2|Bacteria,4NMFG@976|Bacteroidetes,1I1R1@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS2_k127_632762_6	1121875.KB907549_gene1742	3.719e-65	229.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,1I19C@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
CMS2_k127_632762_4	1121875.KB907549_gene1739	3.459e-73	253.0	COG0500@1|root,COG2226@2|Bacteria,4NPPQ@976|Bacteroidetes,1I7D1@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS2_k127_632762_11	1121875.KB907549_gene1738	1.469e-25	106.0	COG3360@1|root,COG3360@2|Bacteria,4NURJ@976|Bacteroidetes,1I534@117743|Flavobacteriia	976|Bacteroidetes	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS2_k127_632762_3	616991.JPOO01000001_gene2804	1.366e-74	261.0	COG1503@1|root,COG1503@2|Bacteria,4NHJS@976|Bacteroidetes,1I0YD@117743|Flavobacteriia,23GPS@178469|Arenibacter	976|Bacteroidetes	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6332612_6	313596.RB2501_08525	2.343e-31	123.0	COG0622@1|root,COG0622@2|Bacteria,4NGFH@976|Bacteroidetes,1HYAG@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS2_k127_6332612_1	313596.RB2501_08475	1.222e-216	679.0	COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,1HY9I@117743|Flavobacteriia	976|Bacteroidetes	EG	H gluconate symporter and related	gntT	-	-	ko:K06155	-	-	-	-	ko00000,ko02000	2.A.8.1.4	-	-	GntP_permease
CMS2_k127_6332612_5	313596.RB2501_08470	1.177e-72	247.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1I1KB@117743|Flavobacteriia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS2_k127_6332612_3	313596.RB2501_08465	1.846e-150	484.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,1HZBK@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid aldolase or racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS2_k127_6332612_2	313596.RB2501_08460	9.827e-178	561.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,1HZ07@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M19	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS2_k127_6332612_4	313596.RB2501_08455	6.715e-103	338.0	2D1GA@1|root,32TAN@2|Bacteria,4NSH6@976|Bacteroidetes,1I4HJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6332612_0	313596.RB2501_08450	0.0	1167.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,1HZJK@117743|Flavobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
CMS2_k127_6368984_3	313596.RB2501_06020	2.667e-93	310.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS2_k127_6368984_1	313596.RB2501_06015	7.169e-121	396.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1HXKZ@117743|Flavobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
CMS2_k127_6368984_4	313596.RB2501_06010	2.356e-74	265.0	COG1587@1|root,COG1587@2|Bacteria,4NNSC@976|Bacteroidetes,1I2TT@117743|Flavobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS2_k127_6368984_0	313596.RB2501_06005	2.853e-193	606.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1HY0P@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS2_k127_6368984_2	1173263.Syn7502_02516	7.958e-102	340.0	COG0408@1|root,COG0408@2|Bacteria,1G1PA@1117|Cyanobacteria,1GZ1D@1129|Synechococcus	1117|Cyanobacteria	H	Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS2_k127_6377369_4	1250232.JQNJ01000001_gene3813	1.494e-38	145.0	28KSE@1|root,2ZBRS@2|Bacteria,4NNCR@976|Bacteroidetes,1I1W2@117743|Flavobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CMS2_k127_6377369_0	313596.RB2501_02795	0.0	1219.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_6377369_2	313596.RB2501_01016	5.014e-88	291.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1I17D@117743|Flavobacteriia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_6377369_1	761193.Runsl_0459	5.816e-139	448.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47JBA@768503|Cytophagia	976|Bacteroidetes	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_6377369_3	1004149.AFOE01000059_gene436	3.703e-69	248.0	2CJWE@1|root,30Y1E@2|Bacteria,4NNQQ@976|Bacteroidetes,1I40A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6383670_1	313596.RB2501_10277	9.374e-30	131.0	2E380@1|root,32Y7Q@2|Bacteria,4NV9Y@976|Bacteroidetes,1IIY0@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
CMS2_k127_6383670_0	313596.RB2501_10282	1.71e-94	337.0	COG1629@1|root,COG1629@2|Bacteria,4NF6X@976|Bacteroidetes,1IJH8@117743|Flavobacteriia	976|Bacteroidetes	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg
CMS2_k127_6385741_2	313596.RB2501_10407	1.551e-73	248.0	COG1216@1|root,COG1216@2|Bacteria,4NI4Q@976|Bacteroidetes,1HXTR@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6385741_0	313596.RB2501_10412	3.108e-267	833.0	COG3118@1|root,COG3118@2|Bacteria,4PMAJ@976|Bacteroidetes,1IJPK@117743|Flavobacteriia	976|Bacteroidetes	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS2_k127_6385741_1	313596.RB2501_10417	4.382e-131	419.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS2_k127_6385741_3	313596.RB2501_10422	0.0008264	43.0	COG0457@1|root,COG1729@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3903@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CMS2_k127_6407907_0	313596.RB2501_01920	0.0	1084.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia	976|Bacteroidetes	O	Molecular chaperone	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
CMS2_k127_644277_4	143224.JQMD01000002_gene1693	6.597e-21	93.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia	976|Bacteroidetes	G	Transporter	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
CMS2_k127_644277_2	1120966.AUBU01000001_gene778	2.247e-102	338.0	COG1028@1|root,COG1028@2|Bacteria,4NH6R@976|Bacteroidetes,47KYG@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K18333	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_644277_0	1286632.P278_18890	1.643e-286	899.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,1HXGZ@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS2_k127_644277_3	1004149.AFOE01000050_gene2612	4.829e-89	302.0	COG3618@1|root,COG3618@2|Bacteria,4NFGB@976|Bacteroidetes,1HYCT@117743|Flavobacteriia	976|Bacteroidetes	S	amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS2_k127_644277_1	1392498.JQLH01000001_gene2736	2.917e-198	623.0	COG4948@1|root,COG4948@2|Bacteria,4NGZF@976|Bacteroidetes,1HZJ0@117743|Flavobacteriia,2PIA7@252356|Maribacter	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS2_k127_6461521_6	313596.RB2501_05165	2.824e-53	189.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1HY16@117743|Flavobacteriia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CMS2_k127_6461521_2	1121875.KB907550_gene662	1.154e-149	479.0	COG4975@1|root,COG4975@2|Bacteria,4NF22@976|Bacteroidetes	976|Bacteroidetes	G	Fatty acid elongase 3-ketoacyl-CoA synthase 1	glcU	-	-	ko:K05340	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Ureide_permease
CMS2_k127_6461521_5	1121875.KB907550_gene663	9.76e-91	308.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,1I0DD@117743|Flavobacteriia	976|Bacteroidetes	G	Sugar kinase	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS2_k127_6461521_4	1121875.KB907550_gene664	1.213e-136	449.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
CMS2_k127_6461521_3	313596.RB2501_05155	2.257e-137	442.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,1HWMH@117743|Flavobacteriia	976|Bacteroidetes	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS2_k127_6461521_0	313596.RB2501_05150	0.0	1151.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS2_k127_6461521_1	313596.RB2501_05145	4.062e-290	893.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1I0C6@117743|Flavobacteriia	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS2_k127_6493820_0	313596.RB2501_02490	3.44e-232	722.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS2_k127_6493820_1	313596.RB2501_02485	3.598e-140	449.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1I0Z6@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_6513086_7	616991.JPOO01000001_gene3539	2.629e-131	436.0	COG0469@1|root,COG0469@2|Bacteria,4NGQX@976|Bacteroidetes,1I0TA@117743|Flavobacteriia,23G5M@178469|Arenibacter	976|Bacteroidetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
CMS2_k127_6513086_13	313596.RB2501_10177	2.764e-69	239.0	COG0668@1|root,COG0668@2|Bacteria,4NP36@976|Bacteroidetes,1I1XC@117743|Flavobacteriia	976|Bacteroidetes	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6513086_0	313596.RB2501_10182	1.628e-270	838.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
CMS2_k127_6513086_8	886377.Murru_0624	8.519e-112	364.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1HWTZ@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS2_k127_6513086_10	313596.RB2501_10192	5.39e-92	309.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6513086_12	313596.RB2501_10197	1.527e-79	274.0	COG2227@1|root,COG2227@2|Bacteria,4PKW0@976|Bacteroidetes,1IJNX@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase domain	cypM_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS2_k127_6513086_11	313596.RB2501_10202	3.322e-80	270.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1HZQ3@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS2_k127_6513086_6	1121875.KB907546_gene2361	1.2e-149	477.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,1HXQV@117743|Flavobacteriia	976|Bacteroidetes	I	Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_6513086_5	313596.RB2501_10212	5.757e-189	597.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS2_k127_6513086_3	313596.RB2501_10217	4.363e-223	696.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS2_k127_6513086_9	313596.RB2501_10232	1.864e-93	314.0	COG2017@1|root,COG2017@2|Bacteria,4NHSZ@976|Bacteroidetes,1I00K@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
CMS2_k127_6513086_4	313596.RB2501_10252	9.937e-217	681.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,1HWK3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
CMS2_k127_6513086_2	313596.RB2501_10257	6.075e-234	728.0	COG0151@1|root,COG0151@2|Bacteria,4NKDM@976|Bacteroidetes,1HYCA@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, C domain	-	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C
CMS2_k127_6513086_14	313596.RB2501_10262	4.957e-54	195.0	COG0454@1|root,COG0456@2|Bacteria,4NVPH@976|Bacteroidetes,1I5U2@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS2_k127_6513086_16	1286632.P278_29870	3.456e-07	54.0	COG3637@1|root,COG3637@2|Bacteria,4NMMV@976|Bacteroidetes,1I1GG@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6513086_1	1120966.AUBU01000002_gene2268	1.422e-263	815.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47UQJ@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS2_k127_6533252_2	313596.RB2501_03030	4.084e-149	477.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CMS2_k127_6533252_5	313596.RB2501_03035	4.114e-74	251.0	29WC5@1|root,30HXS@2|Bacteria,4NNWN@976|Bacteroidetes,1I218@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6533252_0	313596.RB2501_03045	6.243e-215	670.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia	976|Bacteroidetes	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
CMS2_k127_6533252_3	313596.RB2501_03050	9e-143	460.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1HWRY@117743|Flavobacteriia	976|Bacteroidetes	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS2_k127_6533252_1	313596.RB2501_03055	4.8e-194	612.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1HXQX@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_6533252_4	313603.FB2170_17106	1.997e-101	332.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1HXCT@117743|Flavobacteriia,2PGI1@252356|Maribacter	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
CMS2_k127_6535267_6	313603.FB2170_13396	9.728e-05	45.0	2E7SQ@1|root,3327W@2|Bacteria,4NUWY@976|Bacteroidetes,1I5CR@117743|Flavobacteriia,2PHC3@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6535267_3	313596.RB2501_16044	8.392e-90	302.0	COG0737@1|root,COG0737@2|Bacteria,4NR6D@976|Bacteroidetes,1HXWU@117743|Flavobacteriia	976|Bacteroidetes	F	5'-nucleotidase	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
CMS2_k127_6535267_2	313596.RB2501_16049	4.613e-141	459.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1HZAE@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS2_k127_6535267_1	313603.FB2170_16021	9.02e-147	469.0	KOG1573@1|root,2Z822@2|Bacteria,4NFQF@976|Bacteroidetes,1I0JN@117743|Flavobacteriia,2PHC1@252356|Maribacter	976|Bacteroidetes	S	Myo-inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
CMS2_k127_6535267_0	313603.FB2170_16026	1.51e-267	831.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HXMU@117743|Flavobacteriia,2PGEK@252356|Maribacter	976|Bacteroidetes	S	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_6535267_5	313596.RB2501_16054	2.542e-37	142.0	2C4KB@1|root,32YM4@2|Bacteria,4NUZU@976|Bacteroidetes,1I4R3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6535267_4	1250232.JQNJ01000001_gene3641	1.8e-56	199.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS2_k127_6541228_0	313596.RB2501_11502	0.0	1094.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,1HZ2Z@117743|Flavobacteriia	976|Bacteroidetes	QU	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS2_k127_6541228_1	313596.RB2501_11507	3.295e-278	863.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
CMS2_k127_6541228_3	313596.RB2501_11512	2.293e-86	291.0	COG2755@1|root,COG2755@2|Bacteria,4NMGQ@976|Bacteroidetes,1I27M@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS2_k127_6541228_2	313596.RB2501_11522	7.728e-122	395.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1HYD5@117743|Flavobacteriia	976|Bacteroidetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pectate_lyase_3,SGL
CMS2_k127_6542942_1	313596.RB2501_02070	0.0	1202.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1HYVS@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS2_k127_6542942_0	313596.RB2501_02075	0.0	2436.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS2_k127_6542942_5	313596.RB2501_02080	7.991e-62	214.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS2_k127_6542942_3	313596.RB2501_02085	1.772e-88	294.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1HXJG@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS2_k127_6542942_2	313596.RB2501_02090	5.243e-130	420.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1HZJ6@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS2_k127_6542942_4	313596.RB2501_02095	3.051e-80	270.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1I18G@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS2_k127_6548672_1	313596.RB2501_12849	3.618e-85	287.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS2_k127_6548672_2	313596.RB2501_12854	1.914e-66	232.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1I185@117743|Flavobacteriia	976|Bacteroidetes	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS2_k127_6548672_0	313596.RB2501_12859	1.01e-121	396.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,1I24J@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
CMS2_k127_6548672_3	1392490.JHZX01000001_gene118	5.759e-48	179.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,1HYZT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6548672_4	313603.FB2170_15178	4.959e-13	69.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia,2PH06@252356|Maribacter	976|Bacteroidetes	L	PIF1-like helicase	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
CMS2_k127_6555982_4	1121887.AUDK01000010_gene1408	3.106e-150	482.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1HYT2@117743|Flavobacteriia,2NV1V@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CMS2_k127_6555982_3	880070.Cycma_4027	4.287e-163	516.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,47JFJ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	pabB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS2_k127_6555982_0	1305737.JAFX01000001_gene170	0.0	1106.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47N4P@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS2_k127_6555982_8	1453500.AT05_00630	0.0001534	49.0	2E373@1|root,32Y6V@2|Bacteria,4NWZF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6555982_7	926562.Oweho_0443	6.566e-51	183.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,1I3D1@117743|Flavobacteriia,2PBSB@246874|Cryomorphaceae	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CMS2_k127_6555982_5	468059.AUHA01000002_gene563	9.764e-135	452.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
CMS2_k127_6555982_1	1239962.C943_04509	3.185e-174	560.0	COG2937@1|root,COG2937@2|Bacteria,4PPET@976|Bacteroidetes,47YMT@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the GPAT DAPAT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6555982_2	1239962.C943_04508	6.663e-172	552.0	COG2837@1|root,COG2837@2|Bacteria,4P6QA@976|Bacteroidetes,47VZZ@768503|Cytophagia	976|Bacteroidetes	P	iron assimilation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6555982_6	1239962.C943_04507	1.644e-64	224.0	2DBCN@1|root,2Z8EJ@2|Bacteria,4NR8H@976|Bacteroidetes,47QZ8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6556222_1	1286632.P278_24050	1.007e-231	747.0	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,1HWWZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_6556222_0	313596.RB2501_07865	5.255e-275	853.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1HXFR@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS2_k127_6556222_2	313603.FB2170_07150	3.59e-189	599.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1HY2X@117743|Flavobacteriia,2PGI4@252356|Maribacter	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_6556222_3	313596.RB2501_07855	1.253e-170	539.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1HWPD@117743|Flavobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CMS2_k127_6556222_4	313596.RB2501_07850	2.126e-124	404.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS2_k127_6558861_12	313596.RB2501_05070	1.656e-54	192.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
CMS2_k127_6558861_6	313596.RB2501_05065	1.049e-71	244.0	COG0394@1|root,COG0394@2|Bacteria,4NNN6@976|Bacteroidetes,1I2XM@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS2_k127_6558861_7	313596.RB2501_05060	2.509e-69	238.0	COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,1I246@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS2_k127_6558861_9	313596.RB2501_05055	3.056e-62	217.0	2DBYA@1|root,2ZBU9@2|Bacteria,4NPNW@976|Bacteroidetes,1IJ0Y@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6558861_13	313596.RB2501_05050	2.4e-53	188.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1I2TQ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS2_k127_6558861_14	313596.RB2501_05045	9.641e-50	179.0	COG2314@1|root,COG2314@2|Bacteria,4NSVZ@976|Bacteroidetes,1I3HF@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
CMS2_k127_6558861_8	313596.RB2501_05040	2.607e-67	233.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1I1XF@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_6558861_10	313596.RB2501_05035	4.151e-60	224.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS2_k127_6558861_3	313596.RB2501_05020	1.886e-148	475.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS2_k127_6558861_11	1123037.AUDE01000021_gene2148	4.001e-56	198.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS2_k127_6558861_1	313596.RB2501_05015	6.167e-240	748.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1HX2X@117743|Flavobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS2_k127_6558861_5	620914.JH621257_gene1268	1.675e-94	319.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1HXMG@117743|Flavobacteriia,2YIZH@290174|Aquimarina	976|Bacteroidetes	J	Ribosomal RNA adenine dimethylases	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS2_k127_6558861_16	1110697.NCAST_34_00940	8.216e-13	73.0	COG2105@1|root,COG2105@2|Bacteria,2IC9E@201174|Actinobacteria,4G2YY@85025|Nocardiaceae	201174|Actinobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT,Lipase_GDSL_2
CMS2_k127_6558861_15	313596.RB2501_05005	7.351e-39	151.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
CMS2_k127_6558861_0	313596.RB2501_05000	4.164e-281	874.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
CMS2_k127_6558861_2	313596.RB2501_04995	5.902e-216	676.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1HY6A@117743|Flavobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS2_k127_6558861_4	313596.RB2501_04990	7.499e-114	373.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,1HYIU@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
CMS2_k127_657822_1	313596.RB2501_00040	3.864e-120	389.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1HX0E@117743|Flavobacteriia	976|Bacteroidetes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS2_k127_657822_2	313596.RB2501_00051	1.965e-75	256.0	295MU@1|root,2ZSZ8@2|Bacteria,4NP18@976|Bacteroidetes,1I1YU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_657822_0	1121875.KB907546_gene2856	0.0	1662.0	COG1629@1|root,COG1629@2|Bacteria,4PM06@976|Bacteroidetes,1IJK3@117743|Flavobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
CMS2_k127_657822_3	313596.RB2501_00056	3.324e-14	72.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1I202@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS2_k127_6586646_3	1443665.JACA01000001_gene3120	5.197e-65	229.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia,2YGVR@290174|Aquimarina	976|Bacteroidetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS2_k127_6586646_4	313596.RB2501_06805	6.322e-56	209.0	COG2825@1|root,COG2825@2|Bacteria,4NN8F@976|Bacteroidetes,1I21G@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS2_k127_6586646_5	313596.RB2501_06800	3.565e-40	152.0	2CNQU@1|root,32SHJ@2|Bacteria,4NSMZ@976|Bacteroidetes,1I4C3@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CMS2_k127_6586646_0	313596.RB2501_06795	1.808e-211	661.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1HXGT@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
CMS2_k127_6586646_1	313596.RB2501_06790	4.613e-209	655.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1HX73@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS2_k127_6586646_2	313596.RB2501_06785	7.174e-68	238.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia	976|Bacteroidetes	M	Lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS2_k127_6590581_1	313596.RB2501_12814	2.664e-106	349.0	28JEH@1|root,2Z98N@2|Bacteria,4NJHC@976|Bacteroidetes,1I15N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6590581_0	313596.RB2501_12819	1.719e-180	566.0	COG1099@1|root,COG1099@2|Bacteria,4NHVD@976|Bacteroidetes,1I09X@117743|Flavobacteriia	976|Bacteroidetes	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
CMS2_k127_6590581_2	313596.RB2501_12824	7.604e-93	313.0	COG0382@1|root,COG0382@2|Bacteria,4NIXM@976|Bacteroidetes,1HZ5B@117743|Flavobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_6605739_1	313596.RB2501_00676	9.678e-77	262.0	COG2808@1|root,COG2808@2|Bacteria,4NINW@976|Bacteroidetes,1HZF0@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
CMS2_k127_6605739_0	313596.RB2501_00661	2.02e-199	632.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,1HWNJ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2TM,His_kinase
CMS2_k127_6605739_3	616991.JPOO01000003_gene967	4.232e-33	130.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,1HWNJ@117743|Flavobacteriia,23H61@178469|Arenibacter	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2TM,His_kinase
CMS2_k127_6605739_2	313596.RB2501_00651	2.621e-44	164.0	COG2972@1|root,COG2972@2|Bacteria,4NST1@976|Bacteroidetes,1I4BM@117743|Flavobacteriia	976|Bacteroidetes	T	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
CMS2_k127_6605739_4	1121875.KB907546_gene2772	2.796e-27	118.0	COG2972@1|root,COG2972@2|Bacteria,4NV6K@976|Bacteroidetes,1I567@117743|Flavobacteriia	976|Bacteroidetes	T	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
CMS2_k127_6608653_4	313596.RB2501_11252	2.043e-09	62.0	COG0454@1|root,COG0456@2|Bacteria,4NSKZ@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS2_k127_6608653_1	313596.RB2501_11257	1.063e-84	286.0	COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,1I172@117743|Flavobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS2_k127_6608653_0	616991.JPOO01000003_gene1001	2.691e-106	357.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia,23GWH@178469|Arenibacter	976|Bacteroidetes	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS2_k127_6608653_2	867900.Celly_2990	1.446e-17	95.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia,1F8MZ@104264|Cellulophaga	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS2_k127_6608653_3	1341155.FSS13T_07550	1.99e-13	74.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1HWXS@117743|Flavobacteriia,2NTEG@237|Flavobacterium	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS2_k127_6615562_0	313596.RB2501_12537	5.856e-305	944.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS2_k127_6615562_1	1250232.JQNJ01000001_gene2993	9.44e-213	678.0	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,1HXZS@117743|Flavobacteriia	976|Bacteroidetes	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS2_k127_6615562_2	313596.RB2501_12552	1.919e-121	391.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1HWQ1@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS2_k127_6621622_1	313596.RB2501_14229	5.033e-204	642.0	COG2885@1|root,COG2885@2|Bacteria,4PMAU@976|Bacteroidetes,1IJPT@117743|Flavobacteriia	976|Bacteroidetes	M	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_6621622_0	313596.RB2501_14234	4.85e-261	814.0	COG3109@1|root,COG3109@2|Bacteria	2|Bacteria	T	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities	proQ	-	-	ko:K03607	-	-	-	-	ko00000	-	-	-	PorP_SprF,ProQ,SPOR
CMS2_k127_6621622_3	313596.RB2501_14244	8.647e-94	311.0	COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,1IINH@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_6621622_2	1121875.KB907546_gene2693	6.803e-185	592.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_6660118_0	313596.RB2501_14604	6.577e-168	536.0	COG5276@1|root,COG5276@2|Bacteria,4NIBK@976|Bacteroidetes,1I07Z@117743|Flavobacteriia	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS2_k127_6660118_2	313596.RB2501_14599	1.934e-114	371.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1HYWY@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_6660118_1	313596.RB2501_14594	4.616e-126	409.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1HYHF@117743|Flavobacteriia	976|Bacteroidetes	M	Lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS2_k127_6674477_1	1121875.KB907550_gene828	2.073e-63	227.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_6674477_0	313603.FB2170_03670	1.343e-105	355.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.40	ko:K05989,ko:K20541	-	-	-	-	ko00000,ko01000,ko02000	4.D.3.1.6	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,fn3
CMS2_k127_6687739_0	1121012.AUKX01000035_gene844	0.0	1135.0	COG2010@1|root,COG2010@2|Bacteria,4NFP6@976|Bacteroidetes,1HYTP@117743|Flavobacteriia,23GJ7@178469|Arenibacter	976|Bacteroidetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,PSCyt1,PSCyt2,PSD1
CMS2_k127_6691433_2	313596.RB2501_15444	1.166e-161	515.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia	976|Bacteroidetes	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_6691433_1	313596.RB2501_15439	2.795e-257	807.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1HYC9@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
CMS2_k127_6691433_3	313596.RB2501_15434	9.256e-149	479.0	COG1086@1|root,COG1215@1|root,COG1086@2|Bacteria,COG1215@2|Bacteria,4PMAY@976|Bacteroidetes,1IJPZ@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_6691433_5	313596.RB2501_15429	3.91e-103	340.0	COG2755@1|root,COG2755@2|Bacteria,4NHBT@976|Bacteroidetes,1HYY1@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS2_k127_6691433_6	313596.RB2501_15424	5.958e-85	286.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,1HY52@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6691433_0	313596.RB2501_15419	1.587e-291	900.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1HXGY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CMS2_k127_6691433_4	313596.RB2501_15414	2.119e-112	368.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,1HYMD@117743|Flavobacteriia	976|Bacteroidetes	S	dehydrogenases and related proteins	gfo	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_6692993_1	313596.RB2501_00596	1.624e-79	270.0	COG2032@1|root,COG2032@2|Bacteria,4NM88@976|Bacteroidetes,1I17T@117743|Flavobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
CMS2_k127_6692993_0	313596.RB2501_00581	5.913e-104	342.0	COG3637@1|root,COG3637@2|Bacteria,4PKKK@976|Bacteroidetes,1HYEJ@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CMS2_k127_6692993_2	1392498.JQLH01000001_gene2498	3.352e-40	150.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia,2PII7@252356|Maribacter	976|Bacteroidetes	EU	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
CMS2_k127_6693459_3	655815.ZPR_2447	5.109e-28	117.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_6693459_0	313596.RB2501_08565	0.0	1649.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS2_k127_6693459_1	313596.RB2501_08560	5.038e-228	712.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1HY94@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS2_k127_6693459_2	313596.RB2501_08555	6.264e-118	387.0	COG4978@1|root,COG4978@2|Bacteria,4NHII@976|Bacteroidetes,1HYVM@117743|Flavobacteriia	976|Bacteroidetes	KT	PFAM Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
CMS2_k127_671561_1	313596.RB2501_08525	1.223e-135	433.0	COG0622@1|root,COG0622@2|Bacteria,4NGFH@976|Bacteroidetes,1HYAG@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS2_k127_671561_2	313596.RB2501_08545	2.983e-108	357.0	COG3386@1|root,COG3386@2|Bacteria,4NK29@976|Bacteroidetes,1HZAI@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
CMS2_k127_671561_0	1121875.KB907547_gene3101	6.355e-304	937.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HXMU@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS2_k127_6717457_1	313596.RB2501_10587	6.587e-144	459.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS2_k127_6717457_7	1121875.KB907546_gene2484	5.023e-57	207.0	298D5@1|root,30PYQ@2|Bacteria,4NNR2@976|Bacteroidetes,1I21A@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
CMS2_k127_6717457_2	313596.RB2501_10597	1.269e-140	449.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
CMS2_k127_6717457_5	313596.RB2501_10602	2.649e-118	386.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS2_k127_6717457_6	313596.RB2501_10607	9.904e-87	291.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1HWSC@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
CMS2_k127_6717457_0	313596.RB2501_10612	1.102e-177	566.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
CMS2_k127_6717457_3	616991.JPOO01000001_gene3993	3.455e-123	398.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1HY7Y@117743|Flavobacteriia,23GTB@178469|Arenibacter	976|Bacteroidetes	G	Triosephosphate isomerase	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS2_k127_6717457_4	313596.RB2501_10622	2.309e-118	390.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS2_k127_6717457_8	313596.RB2501_10627	0.0001024	46.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the ClpS family	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS2_k127_6732965_2	313596.RB2501_05725	1.908e-13	70.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,1HYBZ@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Major facilitator superfamily MFS-1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_6732965_0	313596.RB2501_05720	5.403e-231	717.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,1HXIS@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_6732965_1	313596.RB2501_05710	1.012e-69	239.0	COG4405@1|root,COG4405@2|Bacteria,4NPD7@976|Bacteroidetes,1I2BF@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG4405 conserved	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
CMS2_k127_6742891_11	313596.RB2501_04460	1.245e-08	58.0	COG5544@1|root,COG5544@2|Bacteria,4NWYR@976|Bacteroidetes,1I596@117743|Flavobacteriia	976|Bacteroidetes	S	Lipoprotein	-	-	-	ko:K05811	-	-	-	-	ko00000	-	-	-	-
CMS2_k127_6742891_8	1313301.AUGC01000006_gene37	4.946e-45	169.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes	976|Bacteroidetes	J	2',5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CMS2_k127_6742891_6	1123248.KB893386_gene1933	2.745e-79	276.0	COG2187@1|root,COG2187@2|Bacteria,4NKD3@976|Bacteroidetes,1IXH4@117747|Sphingobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
CMS2_k127_6742891_9	1122179.KB890428_gene2913	1.153e-35	141.0	COG0645@1|root,COG0645@2|Bacteria,4NSKU@976|Bacteroidetes,1J033@117747|Sphingobacteriia	976|Bacteroidetes	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS2_k127_6742891_10	313596.RB2501_04470	6.37e-31	124.0	COG4103@1|root,COG4103@2|Bacteria,4NWM3@976|Bacteroidetes,1I5QJ@117743|Flavobacteriia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6742891_7	313596.RB2501_04475	1.629e-51	186.0	COG3651@1|root,COG3651@2|Bacteria,4NQDE@976|Bacteroidetes,1I2UH@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
CMS2_k127_6742891_5	313603.FB2170_14863	1.133e-100	331.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1HX32@117743|Flavobacteriia,2PGTZ@252356|Maribacter	976|Bacteroidetes	F	Uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
CMS2_k127_6742891_4	1121875.KB907550_gene743	3.082e-117	388.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1HWZC@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS2_k127_6742891_2	1121875.KB907549_gene2086	1.67e-161	515.0	COG3507@1|root,COG3507@2|Bacteria,4NEWE@976|Bacteroidetes,1HYQA@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynB	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS2_k127_6742891_1	313596.RB2501_04520	2.16e-185	586.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1HY45@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS2_k127_6742891_3	313596.RB2501_04525	1.283e-117	382.0	COG1028@1|root,COG1028@2|Bacteria,4NIH6@976|Bacteroidetes,1IIGH@117743|Flavobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS2_k127_6742891_0	313596.RB2501_04530	1.346e-222	694.0	COG3661@1|root,COG3661@2|Bacteria,4NHE2@976|Bacteroidetes,1HZ1N@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 67 family	aguA	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
CMS2_k127_674798_8	313596.RB2501_05140	3.579e-67	230.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1HYER@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS2_k127_674798_11	313596.RB2501_05135	4.481e-41	156.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS2_k127_674798_6	313596.RB2501_05130	5.07e-117	379.0	COG0527@1|root,COG0527@2|Bacteria,4NJDY@976|Bacteroidetes,1HYZX@117743|Flavobacteriia	976|Bacteroidetes	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_674798_2	313596.RB2501_05125	0.0	1153.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1HWJH@117743|Flavobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS2_k127_674798_0	313596.RB2501_05120	0.0	1788.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS2_k127_674798_7	313596.RB2501_05110	2.783e-93	311.0	COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,1I1BT@117743|Flavobacteriia	976|Bacteroidetes	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS2_k127_674798_1	313596.RB2501_05105	0.0	1401.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1HWQ9@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS2_k127_674798_9	313596.RB2501_05090	2.679e-63	224.0	COG4103@1|root,COG4103@2|Bacteria,4NNTQ@976|Bacteroidetes,1I292@117743|Flavobacteriia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS2_k127_674798_5	313596.RB2501_05085	6.794e-202	630.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1HX4M@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the FBPase class 1 family	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
CMS2_k127_674798_10	616991.JPOO01000001_gene2969	4.026e-63	220.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,1I258@117743|Flavobacteriia,23H6M@178469|Arenibacter	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_674798_4	313596.RB2501_05075	1.321e-220	689.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS2_k127_674798_3	313596.RB2501_05070	3.589e-284	876.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
CMS2_k127_6761506_6	67257.JODR01000015_gene5921	6.366e-26	110.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS2_k127_6761506_5	1461693.ATO10_09278	5.554e-26	118.0	2E03A@1|root,32VS4@2|Bacteria,1N4NZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6761506_7	1121104.AQXH01000001_gene1547	5.531e-25	114.0	2E3AK@1|root,32YA3@2|Bacteria,4PAQ0@976|Bacteroidetes,1IZWF@117747|Sphingobacteriia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6761506_0	1123248.KB893325_gene1224	5.544e-59	211.0	arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6761506_4	1121875.KB907546_gene2692	4.806e-26	119.0	2E3AK@1|root,32TSR@2|Bacteria,4NT8N@976|Bacteroidetes,1I449@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6761506_3	1121875.KB907550_gene764	1.845e-28	124.0	2E3AK@1|root,331MR@2|Bacteria,4NXD2@976|Bacteroidetes,1I65G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6761506_1	1120965.AUBV01000014_gene1146	7.843e-59	212.0	2E3AK@1|root,32SYY@2|Bacteria,4NSTE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6761506_2	313603.FB2170_14253	1.312e-54	199.0	2E3AK@1|root,2ZC5I@2|Bacteria,4NMX3@976|Bacteroidetes,1I1BU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6761506_8	1178825.ALIH01000007_gene1757	7.68e-06	53.0	2E3AK@1|root,331MR@2|Bacteria,4NXD2@976|Bacteroidetes,1I65G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6774191_1	313596.RB2501_03400	1.746e-50	181.0	COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,1I1DV@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	sanA	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
CMS2_k127_6774191_0	1124780.ANNU01000049_gene2169	1.879e-137	453.0	COG1404@1|root,COG1404@2|Bacteria,4NI53@976|Bacteroidetes,47MBD@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
CMS2_k127_6774191_2	1353276.JADR01000008_gene889	1.444e-15	77.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1HZ1U@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS2_k127_6778923_4	313596.RB2501_15864	3.139e-99	329.0	COG4585@1|root,COG4585@2|Bacteria,4NEPS@976|Bacteroidetes,1HYQ1@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_7,TPR_8
CMS2_k127_6778923_3	313596.RB2501_15869	1.547e-114	372.0	COG2197@1|root,COG2197@2|Bacteria,4NHNP@976|Bacteroidetes,1I09Z@117743|Flavobacteriia	976|Bacteroidetes	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_6778923_6	313596.RB2501_15874	8.015e-50	188.0	2DH75@1|root,32U8S@2|Bacteria,4NTVF@976|Bacteroidetes,1I4RG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6778923_1	313596.RB2501_15879	9.055e-234	727.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1HXUW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS2_k127_6778923_0	313596.RB2501_15884	7.364e-246	763.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
CMS2_k127_6778923_2	313596.RB2501_15889	8.125e-207	648.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes,1HWJF@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6778923_7	1341181.FLJC2902T_24650	5.974e-23	103.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1I47G@117743|Flavobacteriia,2NWTE@237|Flavobacterium	976|Bacteroidetes	O	general stress protein	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
CMS2_k127_6778923_5	313596.RB2501_15899	4.989e-71	243.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS2_k127_6786169_4	1121897.AUGO01000015_gene3323	3.523e-64	223.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia,2NWE8@237|Flavobacterium	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS2_k127_6786169_5	313596.RB2501_07030	2.339e-54	193.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1I2VE@117743|Flavobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS2_k127_6786169_2	313596.RB2501_07025	2.881e-187	591.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1HX67@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
CMS2_k127_6786169_0	313596.RB2501_07020	4.963e-196	613.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
CMS2_k127_6786169_1	313596.RB2501_07010	1.849e-188	595.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
CMS2_k127_6786169_3	313596.RB2501_07005	2.584e-135	439.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,1HWTA@117743|Flavobacteriia	976|Bacteroidetes	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_6793904_2	313596.RB2501_15824	1.471e-134	430.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1HXV7@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_6793904_6	313603.FB2170_13166	1.885e-39	161.0	28UMD@1|root,2ZGRX@2|Bacteria,4NN28@976|Bacteroidetes,1I19Y@117743|Flavobacteriia,2PHFS@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6793904_4	313596.RB2501_15819	1.497e-95	318.0	2CCJ7@1|root,2ZA02@2|Bacteria,4NGH8@976|Bacteroidetes,1HXKM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6793904_5	1121875.KB907548_gene1266	5.738e-45	169.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I17E@117743|Flavobacteriia	976|Bacteroidetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS2_k127_6793904_0	313596.RB2501_15809	0.0	1229.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS2_k127_6793904_1	313596.RB2501_15804	4.194e-221	688.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1HXG5@117743|Flavobacteriia	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS2_k127_6793904_3	1121875.KB907548_gene1270	1.734e-109	355.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,1HX9B@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS2_k127_6803560_0	1121875.KB907548_gene1625	1.525e-169	542.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
CMS2_k127_6804365_9	313596.RB2501_12372	2.045e-11	64.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS2_k127_6804365_2	313596.RB2501_12367	1.968e-190	596.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS2_k127_6804365_1	313596.RB2501_12362	1.306e-199	626.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1HWXZ@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS2_k127_6804365_0	313596.RB2501_12357	7.424e-220	684.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS2_k127_6804365_4	313596.RB2501_12352	1.172e-152	485.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS2_k127_6804365_3	1250232.JQNJ01000001_gene2445	2.477e-177	558.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1HWWI@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	tktC	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_6804365_6	313596.RB2501_12342	4.517e-91	303.0	COG3637@1|root,COG3637@2|Bacteria,4NM4E@976|Bacteroidetes,1I1FR@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
CMS2_k127_6804365_5	313596.RB2501_12337	5.787e-104	347.0	COG0545@1|root,COG0545@2|Bacteria,4NJPK@976|Bacteroidetes,1HY2J@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
CMS2_k127_6804365_7	313596.RB2501_12332	1.337e-54	193.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,1I22D@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CMS2_k127_6804365_8	313603.FB2170_00090	1.078e-14	74.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia,2PHA2@252356|Maribacter	976|Bacteroidetes	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS2_k127_680866_3	313596.RB2501_15684	1.024e-86	293.0	COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,1HX5P@117743|Flavobacteriia	976|Bacteroidetes	IQ	O-succinylbenzoic acid--CoA ligase	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS2_k127_680866_1	313596.RB2501_15679	6.321e-233	726.0	COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1HYUR@117743|Flavobacteriia	976|Bacteroidetes	E	Xaa-Pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CMS2_k127_680866_2	313596.RB2501_15674	4.412e-215	684.0	COG0457@1|root,COG4676@1|root,COG0457@2|Bacteria,COG4676@2|Bacteria,4NGJS@976|Bacteroidetes,1HWZQ@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CMS2_k127_680866_0	313596.RB2501_15669	2.074e-304	945.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS2_k127_680866_4	313596.RB2501_15664	2.402e-48	175.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1HY1C@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_6819516_1	313596.RB2501_13779	1.273e-133	430.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HX7D@117743|Flavobacteriia	976|Bacteroidetes	V	Multidrug transporter MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS2_k127_6819516_0	313596.RB2501_13774	0.0	1657.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome c biogenesis	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS2_k127_6819516_3	1380384.JADN01000003_gene656	1.556e-47	182.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1HZIC@117743|Flavobacteriia	976|Bacteroidetes	S	NADP oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
CMS2_k127_6819516_2	313596.RB2501_13764	4.175e-58	203.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
CMS2_k127_6831229_8	313596.RB2501_14489	5.595e-142	452.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1HX2N@117743|Flavobacteriia	976|Bacteroidetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_6831229_11	313596.RB2501_14484	2.111e-85	290.0	COG1360@1|root,COG1360@2|Bacteria,4NPRG@976|Bacteroidetes,1I2FT@117743|Flavobacteriia	976|Bacteroidetes	N	Flagellar Motor Protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS2_k127_6831229_10	313596.RB2501_14479	2.293e-91	304.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1I253@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6831229_6	313596.RB2501_14474	5.175e-158	505.0	COG4667@1|root,COG4667@2|Bacteria,4NF0K@976|Bacteroidetes,1HX96@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS2_k127_6831229_4	313596.RB2501_14469	2.247e-228	727.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CMS2_k127_6831229_0	313596.RB2501_14464	0.0	1101.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS2_k127_6831229_3	313596.RB2501_14454	6.452e-276	851.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1HWPT@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS2_k127_6831229_9	313596.RB2501_14449	4.243e-110	359.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1HXVV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS2_k127_6831229_2	313596.RB2501_14444	2.025e-279	864.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,1HYF9@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS2_k127_6831229_7	313596.RB2501_14439	3.367e-153	494.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1HXZV@117743|Flavobacteriia	976|Bacteroidetes	EGP	major facilitator	araJ	-	-	ko:K08156	-	-	-	-	ko00000,ko02000	2.A.1.2.14	-	-	MFS_1,Sugar_tr
CMS2_k127_6831229_1	313596.RB2501_14434	2.536e-298	919.0	COG1012@1|root,COG1012@2|Bacteria,4NEQ2@976|Bacteroidetes,1HYQ7@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	gapN	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_6831229_5	313596.RB2501_14429	1.15e-190	597.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1HYM2@117743|Flavobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS2_k127_6837089_5	313596.RB2501_15024	1.548e-17	85.0	COG0457@1|root,COG1368@1|root,COG0457@2|Bacteria,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS2_k127_6837089_0	313596.RB2501_15029	2.095e-260	811.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1HY02@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
CMS2_k127_6837089_1	313596.RB2501_15034	8.349e-159	526.0	COG1413@1|root,COG1413@2|Bacteria,4NGY4@976|Bacteroidetes,1II9U@117743|Flavobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS2_k127_6837089_4	1249997.JHZW01000003_gene2687	1.509e-44	166.0	COG0745@1|root,COG0745@2|Bacteria,4NQNT@976|Bacteroidetes,1I3AQ@117743|Flavobacteriia,2PHM2@252356|Maribacter	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_6837089_2	313596.RB2501_15044	1.451e-150	495.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,Y_Y_Y
CMS2_k127_6837089_3	313596.RB2501_15049	6.669e-103	338.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
CMS2_k127_6843499_4	555500.I215_06222	5.328e-32	132.0	COG3934@1|root,COG3934@2|Bacteria,4PMNF@976|Bacteroidetes,1I3IN@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
CMS2_k127_6843499_0	313596.RB2501_10030	4.666e-239	745.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1HY1N@117743|Flavobacteriia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
CMS2_k127_6843499_1	313596.RB2501_10035	3.421e-57	203.0	2AHD2@1|root,317Q0@2|Bacteria,4NQE4@976|Bacteroidetes,1I319@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6843499_3	1121904.ARBP01000006_gene3872	3.699e-39	148.0	COG0346@1|root,COG0346@2|Bacteria,4NQRN@976|Bacteroidetes,47RXX@768503|Cytophagia	976|Bacteroidetes	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
CMS2_k127_6843499_2	313596.RB2501_10040	8.674e-40	150.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS2_k127_6847651_0	313596.RB2501_00476	0.0	1411.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,1HZM2@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Trehalose utilisation	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA
CMS2_k127_6847651_2	313596.RB2501_00486	4.576e-197	623.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HYZH@117743|Flavobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS2_k127_6847651_4	313596.RB2501_00491	2.169e-74	254.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,1I39B@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS2_k127_6847651_1	313596.RB2501_00496	0.0	1271.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HWVV@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
CMS2_k127_6847651_3	313596.RB2501_00501	3.383e-159	506.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS2_k127_685132_2	1250232.JQNJ01000001_gene3666	1.655e-62	224.0	28PKM@1|root,300JA@2|Bacteria,4NMW7@976|Bacteroidetes,1I276@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
CMS2_k127_685132_1	313596.RB2501_12432	2.277e-112	372.0	28PKM@1|root,300JA@2|Bacteria,4NMW7@976|Bacteroidetes,1I276@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
CMS2_k127_685132_0	313596.RB2501_12437	0.0	1348.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_685132_3	313596.RB2501_12442	7.268e-14	72.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
CMS2_k127_6853659_0	313596.RB2501_12307	0.0	1397.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS2_k127_6853659_2	1168289.AJKI01000011_gene493	1.169e-123	404.0	COG1052@1|root,COG1052@2|Bacteria,4NIHV@976|Bacteroidetes,2FPG0@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS2_k127_6853659_3	313596.RB2501_01136	1.407e-99	338.0	COG3279@1|root,COG3279@2|Bacteria,4NHZR@976|Bacteroidetes,1HY42@117743|Flavobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS2_k127_6853659_1	313596.RB2501_01131	4.649e-124	404.0	COG2972@1|root,COG2972@2|Bacteria,4NKSP@976|Bacteroidetes,1HZTX@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS2_k127_6878578_0	1121012.AUKX01000031_gene1054	7.164e-233	728.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,23GYV@178469|Arenibacter	976|Bacteroidetes	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS2_k127_6878578_2	313596.RB2501_14584	1.713e-80	272.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
CMS2_k127_6878578_1	313596.RB2501_14579	4.779e-176	560.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia	976|Bacteroidetes	E	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS2_k127_6902818_3	313596.RB2501_07005	1.059e-40	150.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,1HWTA@117743|Flavobacteriia	976|Bacteroidetes	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS2_k127_6902818_0	313596.RB2501_06995	0.0	1112.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1HYG5@117743|Flavobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS2_k127_6902818_1	886377.Murru_1298	3.549e-295	919.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,4PKJ5@976|Bacteroidetes,1HY50@117743|Flavobacteriia	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS2_k127_6902818_2	313596.RB2501_06985	1.236e-152	492.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1HX48@117743|Flavobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_6922268_0	1121012.AUKX01000004_gene3498	1.48e-274	850.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia,23HV4@178469|Arenibacter	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
CMS2_k127_6948459_2	313596.RB2501_10090	4.819e-219	684.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,1I15X@117743|Flavobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS2_k127_6948459_3	313596.RB2501_10080	6.266e-158	501.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1HY41@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS2_k127_6948459_4	655815.ZPR_0216	4.116e-41	157.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1I3II@117743|Flavobacteriia	976|Bacteroidetes	M	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS2_k127_6948459_0	1121875.KB907546_gene2346	1.503e-249	774.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1HXT4@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS2_k127_6948459_1	313596.RB2501_05390	1.129e-235	740.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HZW3@117743|Flavobacteriia	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS2_k127_6948459_5	926559.JoomaDRAFT_1821	7.03e-16	83.0	2C7PH@1|root,32RJJ@2|Bacteria,4NTQM@976|Bacteroidetes,1I4UU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CMS2_k127_6957460_2	313596.RB2501_14319	6.289e-94	311.0	COG3503@1|root,COG3503@2|Bacteria,4NG0X@976|Bacteroidetes,1HWX2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS2_k127_6957460_1	313596.RB2501_14339	3.498e-149	484.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1HYBN@117743|Flavobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
CMS2_k127_6957460_0	313596.RB2501_14344	1.109e-288	899.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS2_k127_697939_3	313596.RB2501_00266	2.307e-50	184.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,1I2C8@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS2_k127_697939_4	313596.RB2501_00261	5.693e-37	145.0	COG2010@1|root,COG2010@2|Bacteria,4NVNJ@976|Bacteroidetes,1I68I@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_697939_1	313596.RB2501_00251	8.457e-152	482.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_697939_0	313596.RB2501_00246	1.456e-214	678.0	COG0362@1|root,COG0362@2|Bacteria,4NG05@976|Bacteroidetes,1HXYX@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2,SKI
CMS2_k127_697939_2	313596.RB2501_00231	5.354e-55	194.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,1I345@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_697939_5	313596.RB2501_00226	2.285e-17	82.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1HYTA@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS2_k127_7014755_2	886377.Murru_2444	3.964e-47	173.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS2_k127_7014755_0	313596.RB2501_12939	2.085e-206	649.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1HX2J@117743|Flavobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CMS2_k127_7014755_1	313596.RB2501_12944	1.309e-142	458.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1HWW7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS2_k127_7018961_0	313596.RB2501_00201	2.073e-239	747.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1HXNC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS2_k127_7018961_2	313596.RB2501_00211	1.447e-158	508.0	COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,1HWUZ@117743|Flavobacteriia	976|Bacteroidetes	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS2_k127_7018961_3	313596.RB2501_00216	2.155e-135	438.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,1HXH4@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS2_k127_7018961_4	313596.RB2501_00221	1.452e-100	335.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,1HWNQ@117743|Flavobacteriia	976|Bacteroidetes	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS2_k127_7018961_1	313596.RB2501_00226	1.864e-171	546.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1HYTA@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS2_k127_7022524_2	313596.RB2501_16009	2.942e-144	467.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CMS2_k127_7022524_1	1121875.KB907548_gene1225	7.956e-148	473.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1HWJN@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
CMS2_k127_7022524_0	313596.RB2501_16019	1.742e-191	607.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS2_k127_7022524_4	1250232.JQNJ01000001_gene3627	8.553e-52	184.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1I2X0@117743|Flavobacteriia	976|Bacteroidetes	S	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
CMS2_k127_7022524_3	313596.RB2501_16029	8.543e-125	402.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS2_k127_702666_3	313596.RB2501_08040	7.722e-164	518.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1HX6M@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
CMS2_k127_702666_5	313596.RB2501_08045	1.318e-154	492.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1HWP6@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
CMS2_k127_702666_11	313596.RB2501_08050	5.251e-53	193.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1I25J@117743|Flavobacteriia	976|Bacteroidetes	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS2_k127_702666_0	313596.RB2501_08055	0.0	1036.0	COG3408@1|root,COG3408@2|Bacteria,4NHUB@976|Bacteroidetes,1I0MR@117743|Flavobacteriia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
CMS2_k127_702666_1	313596.RB2501_08060	2.081e-296	914.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia	976|Bacteroidetes	J	ribonuclease G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS2_k127_702666_15	746697.Aeqsu_1354	1.333e-06	49.0	2DTGS@1|root,33K9M@2|Bacteria,4NYMF@976|Bacteroidetes,1I6Q5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_702666_12	1004149.AFOE01000003_gene2198	6.835e-53	186.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS2_k127_702666_4	313596.RB2501_08070	4.002e-155	497.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia	976|Bacteroidetes	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS2_k127_702666_9	313596.RB2501_08075	1.509e-69	238.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I27K@117743|Flavobacteriia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS2_k127_702666_2	313596.RB2501_08080	8.557e-227	708.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated protein GldE	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS2_k127_702666_7	313596.RB2501_08085	1.012e-83	281.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1I1EE@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_702666_6	313596.RB2501_08090	6.6e-137	441.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1HXSW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_702666_14	313596.RB2501_08095	1.21e-39	152.0	2DPRW@1|root,3334N@2|Bacteria,4NVB9@976|Bacteroidetes,1I5MZ@117743|Flavobacteriia	976|Bacteroidetes	J	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_702666_10	313596.RB2501_08115	1.386e-56	201.0	2AV2W@1|root,31KST@2|Bacteria,4NRSK@976|Bacteroidetes,1I39E@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
CMS2_k127_702666_8	313596.RB2501_08120	1.275e-76	261.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
CMS2_k127_702666_13	313596.RB2501_08125	1.019e-45	166.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1I2S0@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS2_k127_7037304_1	313596.RB2501_10512	1.257e-223	704.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS2_k127_7037304_4	313596.RB2501_10507	6.481e-125	402.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HYCK@117743|Flavobacteriia	976|Bacteroidetes	H	gtp cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS2_k127_7037304_0	313596.RB2501_10502	7.029e-278	859.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1HY1F@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
CMS2_k127_7037304_8	313596.RB2501_10497	2.014e-33	130.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1I3W5@117743|Flavobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS2_k127_7037304_2	313596.RB2501_10492	4.124e-179	563.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,1HYU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
CMS2_k127_7037304_7	1004149.AFOE01000005_gene2264	3.944e-54	195.0	COG1430@1|root,COG1430@2|Bacteria,4NQ5G@976|Bacteroidetes,1I2TF@117743|Flavobacteriia	976|Bacteroidetes	S	acr, cog1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS2_k127_7037304_6	1004149.AFOE01000005_gene2265	2.96e-56	201.0	COG1670@1|root,COG1670@2|Bacteria,4NNE4@976|Bacteroidetes,1I1AJ@117743|Flavobacteriia	976|Bacteroidetes	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS2_k127_7037304_5	1121875.KB907546_gene2700	9.284e-93	312.0	2A6M8@1|root,30VF2@2|Bacteria,4NNJ4@976|Bacteroidetes,1I2FJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_7037304_9	643867.Ftrac_2337	9.823e-27	110.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS2_k127_7037304_3	313596.RB2501_10482	1.189e-172	550.0	COG1119@1|root,COG1119@2|Bacteria,4NEWY@976|Bacteroidetes,1HXS0@117743|Flavobacteriia	976|Bacteroidetes	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
CMS2_k127_704257_0	1250232.JQNJ01000001_gene164	0.0	1032.0	COG3023@1|root,COG3023@2|Bacteria,4PKIH@976|Bacteroidetes,1IJA2@117743|Flavobacteriia	976|Bacteroidetes	V	Alpha-glucosidase	-	-	3.2.1.20,3.2.1.3	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01790,R01791,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31,GH97	-	GH97_C,GH97_N,Glyco_hydro_97
CMS2_k127_704257_1	313596.RB2501_07740	3.432e-68	235.0	COG2010@1|root,COG2010@2|Bacteria,4NMHQ@976|Bacteroidetes,1I1IQ@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_704257_2	313596.RB2501_07745	2.38e-19	88.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,1HY3H@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
CMS2_k127_7073131_4	313596.RB2501_14264	6.097e-43	159.0	COG0778@1|root,COG0778@2|Bacteria,4NF4K@976|Bacteroidetes,1HY0I@117743|Flavobacteriia	976|Bacteroidetes	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_7073131_2	313596.RB2501_14269	2.617e-191	603.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1HZDU@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
CMS2_k127_7073131_1	313596.RB2501_14274	2.73e-200	634.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1HXKR@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS2_k127_7073131_0	313596.RB2501_14279	4.691e-238	745.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS2_k127_7073131_3	313596.RB2501_14284	1.738e-71	242.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1HX3V@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
CMS2_k127_7083380_2	313596.RB2501_05405	5.843e-41	154.0	2DP4K@1|root,32UKA@2|Bacteria,4NU4M@976|Bacteroidetes,1I3XW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_7083380_0	313596.RB2501_05410	0.0	1927.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
CMS2_k127_7083380_1	313596.RB2501_05415	2.104e-121	400.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
CMS2_k127_7083380_3	313596.RB2501_05430	3.786e-37	140.0	COG3295@1|root,COG3295@2|Bacteria,4PMAA@976|Bacteroidetes,1IJPC@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
CMS2_k127_7087445_6	313596.RB2501_03980	2.008e-46	170.0	COG1638@1|root,COG1638@2|Bacteria,4NGV4@976|Bacteroidetes,1HZ02@117743|Flavobacteriia	976|Bacteroidetes	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS2_k127_7087445_4	1250232.JQNJ01000001_gene3888	2.534e-106	348.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,1HYMQ@117743|Flavobacteriia	976|Bacteroidetes	G	Aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
CMS2_k127_7087445_2	1004149.AFOE01000043_gene1722	5.209e-195	611.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1HXXT@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS2_k127_7087445_1	313596.RB2501_03985	2.244e-224	703.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,1HY2E@117743|Flavobacteriia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
CMS2_k127_7087445_3	313596.RB2501_03990	2.143e-170	542.0	COG0673@1|root,COG0673@2|Bacteria,4NFGY@976|Bacteroidetes,1HZUQ@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_7087445_5	313596.RB2501_11947	5.664e-105	350.0	COG0596@1|root,COG0596@2|Bacteria,4NHS0@976|Bacteroidetes,1I5GA@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS2_k127_7087445_0	616991.JPOO01000003_gene1789	9.792e-300	930.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,23GF9@178469|Arenibacter	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS2_k127_7089505_0	313596.RB2501_03960	2.364e-172	543.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1HZMA@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_7089505_1	313596.RB2501_03955	6.642e-108	353.0	COG3970@1|root,COG3970@2|Bacteria,4NGTH@976|Bacteroidetes,1I0WA@117743|Flavobacteriia	976|Bacteroidetes	S	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
CMS2_k127_711399_9	313596.RB2501_08905	1.134e-16	80.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HX5F@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS2_k127_711399_0	313596.RB2501_08900	0.0	1207.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CMS2_k127_711399_7	313596.RB2501_08890	1.574e-40	151.0	2E33D@1|root,32Y3H@2|Bacteria,4NVRK@976|Bacteroidetes,1I502@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_711399_4	313596.RB2501_08885	3.271e-182	577.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS2_k127_711399_6	313596.RB2501_08880	4.543e-70	242.0	COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,1I2VP@117743|Flavobacteriia	976|Bacteroidetes	M	NlpC P60 family	nlpC	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	LysM,NLPC_P60
CMS2_k127_711399_5	313596.RB2501_08875	5.449e-165	542.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia	976|Bacteroidetes	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
CMS2_k127_711399_2	1121875.KB907547_gene3019	2.828e-281	869.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS2_k127_711399_1	313596.RB2501_08865	0.0	1172.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1HY3A@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS2_k127_711399_3	313596.RB2501_08860	2.031e-199	631.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
CMS2_k127_711399_8	1450525.JATV01000003_gene1743	4.649e-17	83.0	COG1577@1|root,COG1577@2|Bacteria,4NEXC@976|Bacteroidetes,1HY6C@117743|Flavobacteriia,2NTEC@237|Flavobacterium	976|Bacteroidetes	I	GHMP kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_723296_2	313596.RB2501_13679	1.294e-34	134.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1HXX4@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS2_k127_723296_0	313596.RB2501_13674	6.865e-263	813.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1HWNU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS2_k127_723296_1	616991.JPOO01000003_gene136	2.688e-57	200.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia,23GQP@178469|Arenibacter	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
CMS2_k127_734571_2	1250232.JQNJ01000001_gene1252	1.332e-07	55.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS2_k127_734571_0	313596.RB2501_06815	0.0	1050.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1HWN4@117743|Flavobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS2_k127_734571_1	313596.RB2501_06820	1.992e-43	162.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1I2W7@117743|Flavobacteriia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
CMS2_k127_734571_3	985255.APHJ01000021_gene1782	0.0005311	42.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia,2P5HX@244698|Gillisia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
CMS2_k127_797776_1	313596.RB2501_15359	3.329e-36	138.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,1I3ZA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_797776_2	1348583.ATLH01000022_gene2342	0.0005155	46.0	2BYFQ@1|root,311GK@2|Bacteria,4PGA6@976|Bacteroidetes,1IH5E@117743|Flavobacteriia,1FAHD@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_797776_0	313596.RB2501_15369	0.0	1052.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS2_k127_820090_8	313596.RB2501_03510	8.283e-35	135.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS2_k127_820090_2	313596.RB2501_03515	6.839e-204	644.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1HWPI@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS2_k127_820090_4	1121875.KB907550_gene937	1.047e-184	583.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HXN4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
CMS2_k127_820090_1	1121875.KB907550_gene936	3.592e-226	705.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	macB_3	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_820090_7	1121100.JCM6294_3349	1.125e-69	252.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FNZ2@200643|Bacteroidia,4AMP5@815|Bacteroidaceae	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_820090_5	313596.RB2501_03535	7.491e-130	420.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_820090_3	313596.RB2501_03540	4.464e-201	630.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HXN4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
CMS2_k127_820090_0	313596.RB2501_03545	2.456e-240	746.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_820090_6	313596.RB2501_03550	1.921e-115	374.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS2_k127_841228_1	1121875.KB907547_gene3416	4.699e-123	400.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NJ7B@976|Bacteroidetes	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS2_k127_841228_0	1121875.KB907547_gene3420	2.437e-188	593.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,1HYMD@117743|Flavobacteriia	976|Bacteroidetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS2_k127_841228_3	641526.ADIWIN_0445	6.176e-36	146.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes,1I33Z@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_841228_2	391603.FBALC1_11552	5.906e-64	226.0	COG2972@1|root,COG2972@2|Bacteria,4NIVE@976|Bacteroidetes,1HYCB@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CMS2_k127_862862_14	886377.Murru_2801	4.389e-31	123.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1HY30@117743|Flavobacteriia	976|Bacteroidetes	E	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Peptidase_S9
CMS2_k127_862862_8	313596.RB2501_07320	2.995e-117	383.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,1HX82@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS2_k127_862862_7	313596.RB2501_07325	1.559e-131	423.0	COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,1HX1K@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_862862_0	313596.RB2501_07330	4.42e-317	979.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1HWTC@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS2_k127_862862_4	1121875.KB907547_gene3370	2.033e-168	535.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1HX1B@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CMS2_k127_862862_11	616991.JPOO01000003_gene2336	1.802e-81	275.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia,23GSG@178469|Arenibacter	976|Bacteroidetes	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS2_k127_862862_3	313596.RB2501_07345	7.852e-173	548.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1HWZ8@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS2_k127_862862_10	313596.RB2501_07350	1.323e-85	286.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
CMS2_k127_862862_13	313596.RB2501_07355	9.896e-35	132.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1I53M@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS2_k127_862862_2	313596.RB2501_07360	1.96e-187	588.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1HX72@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS2_k127_862862_12	313596.RB2501_07365	1.477e-70	243.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1I1AS@117743|Flavobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS2_k127_862862_1	313596.RB2501_07370	7.389e-289	888.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia	976|Bacteroidetes	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS2_k127_862862_6	313596.RB2501_07375	1.627e-157	505.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS2_k127_862862_15	143224.JQMD01000002_gene3043	4.93e-29	121.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,1I55E@117743|Flavobacteriia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
CMS2_k127_862862_5	313596.RB2501_07380	2.851e-165	524.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,1HXA2@117743|Flavobacteriia	976|Bacteroidetes	E	ABC transporter	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS2_k127_862862_9	313596.RB2501_07385	4.009e-108	351.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl endopeptidase	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS2_k127_866959_2	313596.RB2501_14954	4.866e-144	460.0	COG2304@1|root,COG2304@2|Bacteria,4NI4I@976|Bacteroidetes,1HZMV@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS2_k127_866959_0	313596.RB2501_14964	7.237e-236	739.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS2_k127_866959_3	313596.RB2501_14969	4.336e-93	311.0	COG3023@1|root,COG3023@2|Bacteria,4NMIV@976|Bacteroidetes,1HY6G@117743|Flavobacteriia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
CMS2_k127_866959_4	313596.RB2501_14974	5.115e-38	149.0	COG3584@1|root,COG3584@2|Bacteria,4NSKX@976|Bacteroidetes,1I48D@117743|Flavobacteriia	976|Bacteroidetes	S	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_866959_1	143224.JQMD01000002_gene857	5.451e-170	544.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HY9H@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_866959_5	1380600.AUYN01000001_gene2303	2.052e-07	55.0	COG3919@1|root,COG3919@2|Bacteria,4NMVY@976|Bacteroidetes,1I6Q7@117743|Flavobacteriia	976|Bacteroidetes	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C
CMS2_k127_888256_1	1121875.KB907555_gene383	2.728e-95	312.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1HWYY@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS2_k127_888256_0	313596.RB2501_13284	8.144e-255	792.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CMS2_k127_895310_0	313596.RB2501_12869	4.403e-234	728.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
CMS2_k127_895310_4	313596.RB2501_12874	2.058e-81	274.0	2DM5T@1|root,31U0Y@2|Bacteria,4NMMA@976|Bacteroidetes,1I0IR@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
CMS2_k127_895310_2	313596.RB2501_12879	2.773e-132	424.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1HXV5@117743|Flavobacteriia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS2_k127_895310_3	391587.KAOT1_10026	6.771e-96	320.0	COG1011@1|root,COG1011@2|Bacteria,4NF0Y@976|Bacteroidetes,1HZ7Q@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
CMS2_k127_895310_1	313596.RB2501_12889	1.408e-187	591.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes,1IMM0@117743|Flavobacteriia	976|Bacteroidetes	C	Alcohol dehydrogenase class IV	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
CMS2_k127_895310_5	313603.FB2170_15153	1.422e-79	269.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1I28N@117743|Flavobacteriia,2PHF8@252356|Maribacter	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS2_k127_895310_6	1121875.KB907547_gene3478	1.651e-65	227.0	29UEX@1|root,30FRQ@2|Bacteria,4NNN7@976|Bacteroidetes,1I8KJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_895310_7	1250232.JQNJ01000001_gene2650	7.161e-62	214.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1HY9V@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS2_k127_899168_2	1443665.JACA01000073_gene2041	0.0002746	48.0	2DS4S@1|root,33EHX@2|Bacteria,4NYWS@976|Bacteroidetes,1I6Z0@117743|Flavobacteriia,2YKW2@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_899168_0	313596.RB2501_03930	2.008e-151	482.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CMS2_k127_915385_2	1250232.JQNJ01000001_gene2985	1.656e-110	363.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS2_k127_915385_0	1250232.JQNJ01000001_gene2986	1.35e-218	686.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia	976|Bacteroidetes	M	Biotin attachment protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
CMS2_k127_915385_1	1250232.JQNJ01000001_gene2987	1.937e-173	556.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia	976|Bacteroidetes	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_915385_3	1249997.JHZW01000002_gene1446	3.288e-42	155.0	COG0810@1|root,COG0810@2|Bacteria,4NN8A@976|Bacteroidetes,1I18J@117743|Flavobacteriia,2PH8K@252356|Maribacter	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_922_3	616991.JPOO01000003_gene379	7.315e-11	63.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia,23FVG@178469|Arenibacter	976|Bacteroidetes	S	Penicillin amidase	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS2_k127_922_0	313596.RB2501_14354	0.0	1365.0	COG4773@1|root,COG4773@2|Bacteria,4PMAV@976|Bacteroidetes,1IJPU@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CMS2_k127_922_1	313596.RB2501_14359	4.478e-182	580.0	28I8D@1|root,2Z80E@2|Bacteria,4NG48@976|Bacteroidetes,1I0U8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
CMS2_k127_922_2	313596.RB2501_14364	8.214e-13	71.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M_N
CMS2_k127_956503_0	313596.RB2501_09845	2.622e-221	688.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1HY04@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_956503_1	143224.JQMD01000002_gene3871	1.612e-87	290.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1HWP7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS2_k127_956503_2	1121875.KB907546_gene2301	1.949e-73	247.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1I18N@117743|Flavobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS2_k127_995005_11	313596.RB2501_12637	7.448e-17	80.0	COG0477@1|root,COG2814@2|Bacteria,4NUYS@976|Bacteroidetes,1I53U@117743|Flavobacteriia	976|Bacteroidetes	EGP	membrane	ydzA	-	-	-	-	-	-	-	-	-	-	-	DUF3817
CMS2_k127_995005_9	313596.RB2501_12632	3.027e-69	239.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1I20S@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS2_k127_995005_5	313596.RB2501_12627	1.858e-141	454.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS2_k127_995005_2	313596.RB2501_12622	1.138e-242	756.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Peptidase M20	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_995005_8	313596.RB2501_12617	1.526e-87	291.0	COG1595@1|root,COG1595@2|Bacteria,4NETF@976|Bacteroidetes,1HXWP@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_995005_7	313596.RB2501_12612	9.535e-95	314.0	2AQR4@1|root,31FYV@2|Bacteria,4NQYS@976|Bacteroidetes,1I3DS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_995005_4	313596.RB2501_12607	4.579e-154	489.0	COG0204@1|root,COG0204@2|Bacteria,4NG70@976|Bacteroidetes,1HXMA@117743|Flavobacteriia	976|Bacteroidetes	I	acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_995005_10	1223410.KN050846_gene873	3.306e-58	209.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1HZSH@117743|Flavobacteriia	976|Bacteroidetes	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_995005_6	313596.RB2501_12597	1.191e-107	354.0	COG0652@1|root,COG0652@2|Bacteria,4NMG5@976|Bacteroidetes,1I0CC@117743|Flavobacteriia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS2_k127_995005_3	313596.RB2501_12582	1.854e-194	617.0	COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,1I126@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_995005_1	313596.RB2501_12577	0.0	1159.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia	976|Bacteroidetes	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
CMS2_k127_995005_0	313596.RB2501_12572	0.0	1265.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6B@976|Bacteroidetes,1HZB8@117743|Flavobacteriia	976|Bacteroidetes	CG	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
## 2597 queries scanned
## Total time (seconds): 59.481624364852905
## Rate: 43.66 q/s
