## Tue Oct 15 14:29:15 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/CMS2_bin.75.fa -m mmseqs --itype genome -o CMS2_bin.75 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/CMS2_bin.75 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS2_k127_102730_0	525897.Dbac_1053	6.958e-178	594.0	COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1MVAW@1224|Proteobacteria,42MYC@68525|delta/epsilon subdivisions,2WJXA@28221|Deltaproteobacteria,2M8XJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
CMS2_k127_102730_1	1122165.AUHS01000047_gene3184	4.671e-173	563.0	COG1520@1|root,COG1520@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CMS2_k127_1041095_6	1198232.CYCME_0769	1.391e-97	322.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,4601G@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS2_k127_1041095_3	247633.GP2143_01385	1.998e-155	496.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1J4UB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS2_k127_1041095_9	1453501.JELR01000005_gene1746	1.386e-60	211.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,466UW@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS2_k127_1041095_7	443598.AUFA01000003_gene2144	1.875e-75	261.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,2TVNY@28211|Alphaproteobacteria,3K2NE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CMS2_k127_1041095_0	396588.Tgr7_2295	0.0	1498.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1WX68@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS2_k127_1041095_4	1049564.TevJSym_aa00330	7.527e-147	478.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1J4FQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	major facilitator superfamily	yajR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS2_k127_1041095_8	1123279.ATUS01000006_gene3359	9.019e-62	216.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1J5PI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS2_k127_1041095_5	472759.Nhal_0076	1.735e-136	443.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1WWNM@135613|Chromatiales	135613|Chromatiales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS2_k127_1041095_10	1049564.TevJSym_aa00520	3.759e-44	164.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1J6G6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS2_k127_1041095_11	519989.ECTPHS_04044	1.507e-42	156.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1WYVD@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS2_k127_1041095_2	1479237.JMLY01000001_gene1305	3.321e-157	502.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4647H@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS2_k127_1041095_1	1149133.ppKF707_0229	1.104e-162	520.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1YF5B@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS2_k127_105216_16	1049564.TevJSym_al00680	1.923e-86	291.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1J611@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	narL	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS2_k127_105216_17	1027273.GZ77_04925	1.616e-83	283.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1XJ63@135619|Oceanospirillales	135619|Oceanospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS2_k127_105216_0	1288826.MSNKSG1_03966	0.0	1491.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,464YY@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS2_k127_105216_8	713586.KB900536_gene123	4.43e-159	505.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS2_k127_105216_11	323261.Noc_0849	1.475e-120	402.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1WWPM@135613|Chromatiales	135613|Chromatiales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS2_k127_105216_1	396588.Tgr7_1182	2.426e-282	878.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS2_k127_105216_9	396588.Tgr7_1183	1.178e-146	468.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1WWZU@135613|Chromatiales	135613|Chromatiales	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS2_k127_105216_7	870187.Thini_4167	2.429e-195	617.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS2_k127_105216_25	519989.ECTPHS_12378	3.337e-27	112.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
CMS2_k127_105216_15	765910.MARPU_02650	4.749e-87	293.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1WXHT@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CMS2_k127_105216_19	1123400.KB904750_gene641	1.355e-74	253.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,460TS@72273|Thiotrichales	72273|Thiotrichales	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CMS2_k127_105216_13	243233.MCA2519	4.406e-98	332.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1XDYC@135618|Methylococcales	135618|Methylococcales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS2_k127_105216_23	323261.Noc_1906	1.835e-57	205.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1X2FV@135613|Chromatiales	135613|Chromatiales	S	Smr protein	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS2_k127_105216_12	472759.Nhal_2432	1.988e-115	376.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS2_k127_105216_20	1469245.JFBG01000039_gene1772	8.299e-73	252.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1WX9P@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS2_k127_105216_18	1049564.TevJSym_au00600	4.917e-83	280.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1J6R2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	Z012_09465	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS2_k127_105216_22	1026882.MAMP_01297	2.117e-61	221.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,460ZS@72273|Thiotrichales	72273|Thiotrichales	D	Peptidase family M23	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
CMS2_k127_105216_10	396588.Tgr7_1436	6.465e-129	420.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1WVWC@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM RNA polymerase sigma factor RpoS	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_105216_26	472759.Nhal_2639	1.364e-22	102.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,1SD91@1236|Gammaproteobacteria,1X23R@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
CMS2_k127_105216_2	519989.ECTPHS_03512	5.451e-228	710.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,1WWV0@135613|Chromatiales	135613|Chromatiales	E	aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_105216_4	1121004.ATVC01000003_gene433	7.382e-226	704.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,2KQA0@206351|Neisseriales	206351|Neisseriales	E	Aminotransferase AlaT	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_105216_5	697282.Mettu_1040	1.322e-210	661.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1XEDH@135618|Methylococcales	135618|Methylococcales	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS2_k127_105216_6	1049564.TevJSym_ba00260	7.947e-210	656.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria	1224|Proteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_105216_24	1049564.TevJSym_ba00250	9.34e-48	185.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1S23W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	rpfE	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_105216_3	1215092.PA6_018_00540	5.158e-227	718.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1YD0H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	DHH family	recJ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS2_k127_105216_14	1121033.AUCF01000013_gene1632	1.42e-90	322.0	COG0642@1|root,COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,2JR29@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,dCache_1
CMS2_k127_105216_21	395961.Cyan7425_0692	5.35e-67	236.0	COG0500@1|root,COG2226@2|Bacteria,1G0WT@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS2_k127_1073288_3	1172186.KB911480_gene5635	7.557e-121	406.0	COG0069@1|root,COG2146@1|root,COG0069@2|Bacteria,COG2146@2|Bacteria,2GME2@201174|Actinobacteria,234V0@1762|Mycobacteriaceae	201174|Actinobacteria	EP	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_9,Glu_syn_central,Glu_synthase,Rieske
CMS2_k127_1073288_9	396588.Tgr7_0597	1.649e-28	121.0	28J26@1|root,2Z8YT@2|Bacteria,1R7S5@1224|Proteobacteria,1RNDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
CMS2_k127_1073288_4	395961.Cyan7425_2540	1.871e-102	336.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,3KH1T@43988|Cyanothece	1117|Cyanobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS2_k127_1073288_1	472759.Nhal_1532	2.517e-129	422.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales	135613|Chromatiales	BQ	PFAM histone deacetylase superfamily	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
CMS2_k127_1073288_6	1123393.KB891326_gene36	6.938e-89	298.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2VR0S@28216|Betaproteobacteria,1KSTC@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_1073288_5	697282.Mettu_3018	2.525e-93	319.0	COG0665@1|root,COG0665@2|Bacteria,1QJKZ@1224|Proteobacteria,1THMM@1236|Gammaproteobacteria,1XEVH@135618|Methylococcales	135618|Methylococcales	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS2_k127_1073288_10	1042375.AFPL01000013_gene2438	5.641e-26	113.0	COG2995@1|root,COG2995@2|Bacteria,1NA1F@1224|Proteobacteria,1SERF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
CMS2_k127_1073288_0	536019.Mesop_0931	4.36e-168	542.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,2TSN9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS2_k127_1073288_8	1049564.TevJSym_ae00950	4.639e-41	154.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,1J6VI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulators	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,LMWPc
CMS2_k127_1073288_2	1123392.AQWL01000008_gene1249	1.811e-125	413.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VN77@28216|Betaproteobacteria,1KS6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_1073288_7	1049564.TevJSym_ae00910	3.008e-67	230.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1J4TF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_1074645_8	391615.ABSJ01000037_gene826	7.588e-88	297.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1J5GE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS2_k127_1074645_4	1049564.TevJSym_bh00320	2.059e-143	461.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RYWC@1236|Gammaproteobacteria,1JB8E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS2_k127_1074645_10	1255043.TVNIR_3062	1.285e-36	143.0	COG4319@1|root,COG4319@2|Bacteria,1NX6E@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS2_k127_1074645_7	105559.Nwat_2957	8.026e-110	364.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1WYC8@135613|Chromatiales	135613|Chromatiales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_1074645_0	1415778.JQMM01000001_gene240	1.394e-257	804.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1J851@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
CMS2_k127_1074645_17	525897.Dbac_0479	0.0003116	44.0	COG1246@1|root,COG1246@2|Bacteria,1R0RF@1224|Proteobacteria	1224|Proteobacteria	E	TIGRFAM C_GCAxxG_C_C family protein	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
CMS2_k127_1074645_3	713586.KB900536_gene1785	2.659e-152	487.0	COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,1S1PQ@1236|Gammaproteobacteria,1WY04@135613|Chromatiales	135613|Chromatiales	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1074645_5	225937.HP15_854	4.694e-122	397.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1R4VS@1224|Proteobacteria,1S209@1236|Gammaproteobacteria,466KG@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1074645_15	761193.Runsl_4623	3.197e-13	72.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS2_k127_1074645_2	76114.ebA7143	2.375e-155	505.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2VIZI@28216|Betaproteobacteria,2KUZ6@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS2_k127_1074645_6	76114.ebA7146	3.491e-112	366.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VIV6@28216|Betaproteobacteria,2KUJX@206389|Rhodocyclales	206389|Rhodocyclales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_1074645_11	305700.B447_02236	1.307e-30	124.0	COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,2VWE0@28216|Betaproteobacteria,2KX5T@206389|Rhodocyclales	206389|Rhodocyclales	S	Propeptide PepSY amd peptidase M4	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
CMS2_k127_1074645_13	76114.ebA7151	9.758e-16	81.0	COG5591@1|root,COG5591@2|Bacteria,1NA83@1224|Proteobacteria,2VWEN@28216|Betaproteobacteria,2KXK4@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
CMS2_k127_1074645_1	1454004.AW11_00620	1.667e-170	545.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,2VJFD@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ferric reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
CMS2_k127_1074645_9	670307.HYPDE_24243	7.472e-75	259.0	COG3658@1|root,COG3658@2|Bacteria	2|Bacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	DHC,Ni_hydr_CYTB
CMS2_k127_1074645_12	344747.PM8797T_26200	5.017e-23	112.0	COG1512@1|root,COG1512@2|Bacteria,2J44M@203682|Planctomycetes	203682|Planctomycetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
CMS2_k127_1074645_16	220664.PFL_2776	3.57e-11	66.0	2E9HZ@1|root,333R0@2|Bacteria,1P0AQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1080946_9	713587.THITH_00765	8.785e-41	153.0	2B9UG@1|root,3237D@2|Bacteria,1RIGI@1224|Proteobacteria,1S831@1236|Gammaproteobacteria,1WYI0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1080946_0	472759.Nhal_2290	3.547e-274	864.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1WXXX@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS2_k127_1080946_1	1121935.AQXX01000112_gene5702	2.384e-248	777.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XHRW@135619|Oceanospirillales	135619|Oceanospirillales	P	Phosphate transport system permease protein	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS2_k127_1080946_4	379731.PST_4024	6.826e-141	451.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1Z1PF@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS2_k127_1080946_6	1304275.C41B8_02197	2.364e-96	320.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS2_k127_1080946_3	391615.ABSJ01000027_gene196	1.19e-147	473.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1J4QF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS2_k127_1080946_2	1049564.TevJSym_bp00160	3.855e-170	543.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1J5CN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG4992 Ornithine acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_1080946_5	396588.Tgr7_2463	1.392e-102	335.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1WWRN@135613|Chromatiales	135613|Chromatiales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS2_k127_1080946_7	309807.SRU_2488	3.245e-85	288.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,1FK2H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_1080946_8	396588.Tgr7_2203	7.431e-46	169.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1S7EZ@1236|Gammaproteobacteria,1X01B@135613|Chromatiales	135613|Chromatiales	I	Membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS2_k127_1083231_1	1232683.ADIMK_0084	4.163e-259	811.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS2_k127_1083231_3	652103.Rpdx1_3644	8.61e-151	486.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2U3P9@28211|Alphaproteobacteria,3JRA5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS2_k127_1083231_2	391600.ABRU01000056_gene545	1.809e-182	590.0	COG1404@1|root,COG1404@2|Bacteria,1QVJR@1224|Proteobacteria,2TWGK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS2_k127_1083231_4	1301098.PKB_2923	2.184e-81	288.0	COG2333@1|root,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria	1224|Proteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_1083231_6	1158165.KB898872_gene730	8.786e-75	269.0	COG3359@1|root,COG3359@2|Bacteria,1R5KG@1224|Proteobacteria,1RY3P@1236|Gammaproteobacteria,1WXHZ@135613|Chromatiales	135613|Chromatiales	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
CMS2_k127_1083231_0	1255043.TVNIR_0152	0.0	1232.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,1S0XD@1236|Gammaproteobacteria,1WXNC@135613|Chromatiales	135613|Chromatiales	L	DEAD DEAH box	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
CMS2_k127_1083231_5	2340.JV46_25240	9.817e-80	273.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RXB4@1236|Gammaproteobacteria,1JAMN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS2_k127_1109583_1	765911.Thivi_2388	2.992e-116	379.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1WVYQ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS2_k127_1109583_7	1123399.AQVE01000001_gene748	1.387e-40	160.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S953@1236|Gammaproteobacteria,463PI@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function, DUF484	-	-	-	-	-	-	-	-	-	-	-	-	DUF484
CMS2_k127_1109583_3	1049564.TevJSym_at00460	2.936e-109	362.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1J4JX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS2_k127_1109583_6	765913.ThidrDRAFT_3378	2.439e-43	163.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1WYD9@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS2_k127_1109583_5	765911.Thivi_3086	1.058e-44	171.0	292F7@1|root,2ZPZF@2|Bacteria,1RGFI@1224|Proteobacteria,1S48P@1236|Gammaproteobacteria,1WY8A@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1109583_11	519989.ECTPHS_08613	8.676e-22	95.0	2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,1SGAI@1236|Gammaproteobacteria,1WZTM@135613|Chromatiales	135613|Chromatiales	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
CMS2_k127_1109583_12	1232410.KI421413_gene660	4.926e-10	64.0	28T91@1|root,2ZFHN@2|Bacteria,1P659@1224|Proteobacteria,433I9@68525|delta/epsilon subdivisions,2WX6G@28221|Deltaproteobacteria,43VY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1109583_8	1101195.Meth11DRAFT_1787	1.643e-30	130.0	COG4520@1|root,COG4520@2|Bacteria,1RIHU@1224|Proteobacteria,2VTAT@28216|Betaproteobacteria,2KNS8@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
CMS2_k127_1109583_4	96561.Dole_1668	1.111e-108	359.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,42PUV@68525|delta/epsilon subdivisions,2WKCH@28221|Deltaproteobacteria,2MJRG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
CMS2_k127_1109583_2	1042377.AFPJ01000028_gene2277	1.767e-112	368.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,464SQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS2_k127_1109583_13	555079.Toce_1552	4.156e-05	46.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,24CJP@186801|Clostridia,42HPC@68295|Thermoanaerobacterales	186801|Clostridia	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS2_k127_1109583_0	686340.Metal_2703	2.229e-183	584.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XE53@135618|Methylococcales	135618|Methylococcales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS2_k127_1109583_10	391625.PPSIR1_00290	7.608e-24	112.0	COG1235@1|root,COG1235@2|Bacteria	2|Bacteria	P	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	3.1.4.55	ko:K06136,ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS2_k127_1109583_9	391625.PPSIR1_00265	9.078e-25	107.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_114674_2	754477.Q7C_2220	7.082e-188	590.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,4603H@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS2_k127_114674_27	1415755.JQLV01000002_gene720	6.035e-43	168.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1XHPV@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_114674_42	204669.Acid345_4422	7.001e-08	59.0	2ESYU@1|root,33KH1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_114674_23	765914.ThisiDRAFT_1351	3.331e-50	185.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1WZS4@135613|Chromatiales	135613|Chromatiales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS2_k127_114674_7	640081.Dsui_1449	2.028e-149	502.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
CMS2_k127_114674_22	1120999.JONM01000025_gene3022	1.61e-53	197.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,2KR64@206351|Neisseriales	206351|Neisseriales	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS2_k127_114674_35	983917.RGE_46490	1.447e-35	143.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,1KJ7M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS2_k127_114674_40	1117647.M5M_19385	2.056e-18	89.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,1S50X@1236|Gammaproteobacteria,1J761@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS2_k127_114674_8	697282.Mettu_3552	2.144e-113	370.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XDV4@135618|Methylococcales	135618|Methylococcales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS2_k127_114674_20	323261.Noc_0138	3.833e-61	216.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1WW8M@135613|Chromatiales	135613|Chromatiales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS2_k127_114674_16	396588.Tgr7_2235	2.036e-76	262.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS2_k127_114674_4	1286106.MPL1_01229	3.939e-166	528.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,45ZRZ@72273|Thiotrichales	72273|Thiotrichales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS2_k127_114674_26	1049564.TevJSym_be00120	2.524e-47	173.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1J6J3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Thioesterase superfamily	ybgC	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_0747,iSDY_1059.SDY_0684	4HBT
CMS2_k127_114674_14	105559.Nwat_0131	1.111e-84	286.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
CMS2_k127_114674_30	1515746.HR45_11780	2.587e-41	158.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,2QBQU@267890|Shewanellaceae	1236|Gammaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
CMS2_k127_114674_37	713586.KB900536_gene1047	1.224e-32	138.0	COG3064@1|root,COG3064@2|Bacteria,1R7WR@1224|Proteobacteria,1SZ86@1236|Gammaproteobacteria,1WWRY@135613|Chromatiales	135613|Chromatiales	M	TonB C terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
CMS2_k127_114674_6	519989.ECTPHS_02194	4.854e-159	512.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales	135613|Chromatiales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS2_k127_114674_33	243233.MCA1230	2.667e-40	156.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1XF3T@135618|Methylococcales	135618|Methylococcales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS2_k127_114674_25	713586.KB900536_gene1044	1.964e-47	180.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales	135613|Chromatiales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
CMS2_k127_114674_11	396588.Tgr7_2226	1.058e-98	328.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1WW37@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS2_k127_114674_10	1123393.KB891316_gene1511	3.27e-103	340.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1KS0G@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Queuosine biosynthesis protein QueC	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS2_k127_114674_3	396588.Tgr7_2224	5.561e-178	567.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS2_k127_114674_1	393595.ABO_1737	4.59e-239	755.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XIPX@135619|Oceanospirillales	135619|Oceanospirillales	S	mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS2_k127_114674_15	1245471.PCA10_44530	2.112e-78	267.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1YD84@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2500,iBWG_1329.BWG_2264,iECDH10B_1368.ECDH10B_2666,iECDH1ME8569_1439.ECDH1ME8569_2426,iEcDH1_1363.EcDH1_1169,iJO1366.b2500,iJR904.b2500,iY75_1357.Y75_RS13050	Formyl_trans_N
CMS2_k127_114674_5	377629.TERTU_3013	3.364e-161	515.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,2PMV3@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	F	AIR synthase related protein, N-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2340	AIRS,AIRS_C
CMS2_k127_114674_31	519989.ECTPHS_02931	1.098e-40	165.0	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	VV2512	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
CMS2_k127_114674_24	768671.ThimaDRAFT_1855	6.89e-48	178.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1WY27@135613|Chromatiales	135613|Chromatiales	I	PFAM CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS2_k127_114674_9	1122201.AUAZ01000001_gene2464	5.357e-111	370.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,467K0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	AI-2E family transporter	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS2_k127_114674_17	32042.PstZobell_01837	9.887e-73	252.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1Z0AS@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Belongs to the DnaA family. HdA subfamily	hda	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
CMS2_k127_114674_38	1268237.G114_12734	8.366e-26	111.0	COG3308@1|root,COG3308@2|Bacteria,1N134@1224|Proteobacteria,1S8XA@1236|Gammaproteobacteria,1Y5Y2@135624|Aeromonadales	135624|Aeromonadales	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
CMS2_k127_114674_13	572477.Alvin_1633	7.998e-90	301.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1WW1Q@135613|Chromatiales	135613|Chromatiales	S	Belongs to the WrbA family	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS2_k127_114674_29	2340.JV46_13800	1.651e-41	155.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1J6QP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS2_k127_114674_36	713586.KB900536_gene1070	1.506e-34	140.0	COG1652@1|root,COG1652@2|Bacteria,1NKUE@1224|Proteobacteria,1SW3N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS2_k127_114674_18	1049564.TevJSym_as00630	5.679e-63	221.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,1S75J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
CMS2_k127_114674_28	1123518.ARWI01000001_gene2371	7.724e-43	164.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_114674_19	545276.KB898725_gene864	1.055e-61	218.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
CMS2_k127_114674_12	713586.KB900536_gene2551	4.016e-91	315.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,1WXQ5@135613|Chromatiales	135613|Chromatiales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_114674_32	713586.KB900536_gene2550	2.249e-40	159.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cmeE	-	-	ko:K03585,ko:K18901	ko01501,ko01503,map01501,map01503	M00646,M00647,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_114674_39	765910.MARPU_07915	9.514e-23	101.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1WZC1@135613|Chromatiales	135613|Chromatiales	C	acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS2_k127_114674_21	1415780.JPOG01000001_gene1037	1.016e-56	207.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1X6G6@135614|Xanthomonadales	135614|Xanthomonadales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS2_k127_114674_34	396588.Tgr7_0230	1.599e-39	155.0	COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,1X1C5@135613|Chromatiales	135613|Chromatiales	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS2_k127_114674_0	1396858.Q666_01645	1.267e-279	869.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,4652J@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS2_k127_1165512_25	469595.CSAG_04798	9.225e-09	57.0	2DTVF@1|root,33MUB@2|Bacteria,1NIN2@1224|Proteobacteria,1SHHE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1165512_3	713586.KB900536_gene1194	2.34e-194	613.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS2_k127_1165512_7	1042375.AFPL01000021_gene3845	1.659e-131	436.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
CMS2_k127_1165512_8	1049564.TevJSym_as00030	6.659e-125	409.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1J569@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032	AnmK
CMS2_k127_1165512_1	472759.Nhal_0580	1.393e-196	617.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1WWHU@135613|Chromatiales	135613|Chromatiales	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS2_k127_1165512_20	713586.KB900536_gene1197	4.34e-56	198.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1WYPN@135613|Chromatiales	135613|Chromatiales	C	Iron--sulfur cluster insertion protein erpA	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
CMS2_k127_1165512_22	395493.BegalDRAFT_1306	2.678e-41	156.0	COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,461BH@72273|Thiotrichales	72273|Thiotrichales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS2_k127_1165512_23	626887.J057_04276	8.19e-32	133.0	2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,467DY@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1165512_4	1049564.TevJSym_as00070	6.41e-165	524.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1J549@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iSSON_1240.SSON_4131	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_1165512_6	580332.Slit_0922	1.561e-132	436.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2VHFE@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Chloride channel	clcA	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
CMS2_k127_1165512_21	713586.KB900536_gene1201	5.427e-51	185.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,1X1I8@135613|Chromatiales	135613|Chromatiales	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_1165512_18	580332.Slit_2815	2.524e-60	213.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,44VVU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS2_k127_1165512_12	1207063.P24_05384	1.152e-86	300.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,2TVXP@28211|Alphaproteobacteria,2JQQ3@204441|Rhodospirillales	204441|Rhodospirillales	P	COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS2_k127_1165512_19	1207063.P24_05389	4.521e-57	204.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2U9G4@28211|Alphaproteobacteria,2JSRU@204441|Rhodospirillales	204441|Rhodospirillales	P	Belongs to the Fur family	np20	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
CMS2_k127_1165512_14	1528106.JRJE01000031_gene3213	3.07e-78	269.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,2JQ8C@204441|Rhodospirillales	204441|Rhodospirillales	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	-	-	ko:K02074,ko:K09817	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
CMS2_k127_1165512_10	396588.Tgr7_2749	7.998e-96	323.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1108 ABC-type Mn2 Zn2 transport systems permease components	znuB	GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	iEC042_1314.EC042_2026,iECABU_c1320.ECABU_c21210,iECED1_1282.ECED1_2064,iECNA114_1301.ECNA114_1921,iECSF_1327.ECSF_1717,iECUMN_1333.ECUMN_2157,iEcSMS35_1347.EcSMS35_1327,iG2583_1286.G2583_2311,iSSON_1240.SSON_1282,iYL1228.KPN_02374,ic_1306.c2273	ABC-3
CMS2_k127_1165512_15	395493.BegalDRAFT_2930	9.27e-76	258.0	COG0235@1|root,COG0235@2|Bacteria,1QAVF@1224|Proteobacteria,1RW3I@1236|Gammaproteobacteria,4628Z@72273|Thiotrichales	72273|Thiotrichales	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS2_k127_1165512_9	396588.Tgr7_2419	6.399e-115	375.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1WXAI@135613|Chromatiales	135613|Chromatiales	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS2_k127_1165512_16	1049564.TevJSym_as00130	2.483e-64	226.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1J6HM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS2_k127_1165512_0	396588.Tgr7_2421	1.847e-212	666.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1WWJU@135613|Chromatiales	135613|Chromatiales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_1165512_5	1049564.TevJSym_as00150	4.958e-139	465.0	COG0586@1|root,COG0586@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,1JAB5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acid phosphatase homologues	lssY	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	LssY_C,PAP2,SNARE_assoc
CMS2_k127_1165512_11	396588.Tgr7_0294	4.813e-87	298.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,1X0UF@135613|Chromatiales	135613|Chromatiales	NU	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
CMS2_k127_1165512_24	292415.Tbd_1111	9.128e-31	126.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,2VWT7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1165512_17	395493.BegalDRAFT_3005	6.049e-62	219.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,1S54H@1236|Gammaproteobacteria,462T3@72273|Thiotrichales	72273|Thiotrichales	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
CMS2_k127_1165512_13	1042375.AFPL01000008_gene3320	6.793e-85	286.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,4665N@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CMS2_k127_1165512_2	396588.Tgr7_2447	1.486e-196	621.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1WWVU@135613|Chromatiales	135613|Chromatiales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_1183366_6	338966.Ppro_2172	7.309e-137	450.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q6R@68525|delta/epsilon subdivisions,2WJN4@28221|Deltaproteobacteria,43TK0@69541|Desulfuromonadales	1224|Proteobacteria	T	Domains REC, sigma54 interaction, HTH8	zraR	-	-	ko:K20919	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
CMS2_k127_1183366_32	1118235.CAJH01000004_gene230	4.097e-09	66.0	2ATC8@1|root,31IVA@2|Bacteria,1QGIV@1224|Proteobacteria,1TDYV@1236|Gammaproteobacteria,1XB7J@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1183366_31	557598.LHK_00160	1.426e-10	70.0	2EFVM@1|root,339MV@2|Bacteria,1NH9A@1224|Proteobacteria,2WFHH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1183366_18	1502770.JQMG01000001_gene804	3.351e-47	184.0	2DPA8@1|root,3317I@2|Bacteria,1NAQ0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1183366_19	1429851.X548_13055	2.383e-42	170.0	2DM0S@1|root,317K8@2|Bacteria,1RM4S@1224|Proteobacteria,1S7UJ@1236|Gammaproteobacteria,1X9ZW@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1183366_13	1385515.N791_01095	7.601e-75	258.0	COG3271@1|root,COG3271@2|Bacteria,1RECA@1224|Proteobacteria,1S5HX@1236|Gammaproteobacteria,1X5KX@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidase	-	-	-	ko:K06992	-	-	-	-	ko00000	-	-	-	Peptidase_C39
CMS2_k127_1183366_33	637389.Acaty_c0528	0.0001428	53.0	2EU5Q@1|root,33MNB@2|Bacteria,1NNEH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1183366_10	1502770.JQMG01000001_gene799	5.345e-100	342.0	COG3637@1|root,COG3637@2|Bacteria,1R4GF@1224|Proteobacteria,2VPXP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS2_k127_1183366_25	768671.ThimaDRAFT_3131	7.661e-28	115.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WZ4M@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
CMS2_k127_1183366_12	519989.ECTPHS_11405	4.22e-92	310.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1WWUU@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_1183366_14	768671.ThimaDRAFT_3133	4.192e-67	237.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WWT5@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CMS2_k127_1183366_4	572477.Alvin_2676	4.798e-147	474.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RX39@1236|Gammaproteobacteria,1WXEH@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS2_k127_1183366_3	765914.ThisiDRAFT_0493	3.071e-177	568.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWWZ@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,RnfC_N,SLBB
CMS2_k127_1183366_15	243233.MCA2823	7.364e-67	232.0	COG2878@1|root,COG2878@2|Bacteria,1RE44@1224|Proteobacteria,1S5MU@1236|Gammaproteobacteria,1XF1N@135618|Methylococcales	135618|Methylococcales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
CMS2_k127_1183366_11	1249627.D779_3659	1.276e-92	307.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RZY6@1236|Gammaproteobacteria,1WX9M@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_1183366_5	765914.ThisiDRAFT_1338	5.667e-147	483.0	COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,1RQ1E@1236|Gammaproteobacteria,1WW44@135613|Chromatiales	135613|Chromatiales	T	nitrogen fixation negative regulator NifL	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_9
CMS2_k127_1183366_1	765914.ThisiDRAFT_1339	3.098e-214	676.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1WX1Q@135613|Chromatiales	135613|Chromatiales	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
CMS2_k127_1183366_0	1232683.ADIMK_3036	1.775e-242	760.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria,4660G@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Dinitrogenase iron-molybdenum cofactor	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Fer4_14,Nitro_FeMo-Co,Radical_SAM
CMS2_k127_1183366_23	322710.Avin_51020	7.049e-36	138.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	fdxN	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
CMS2_k127_1183366_20	1173028.ANKO01000056_gene2237	4.03e-39	150.0	COG1393@1|root,COG1393@2|Bacteria,1G68J@1117|Cyanobacteria,1HB71@1150|Oscillatoriales	1117|Cyanobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
CMS2_k127_1183366_17	870187.Thini_4419	1.414e-47	179.0	2BDS5@1|root,327FW@2|Bacteria,1N15E@1224|Proteobacteria,1RSEH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM NifQ	nifQ	-	-	ko:K15790	-	-	-	-	ko00000	-	-	-	NifQ
CMS2_k127_1183366_8	1485544.JQKP01000001_gene990	3.51e-111	367.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,2VM8T@28216|Betaproteobacteria,44WBK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
CMS2_k127_1183366_29	324602.Caur_3270	1.038e-13	83.0	COG0739@1|root,COG1572@1|root,COG3227@1|root,COG5640@1|root,COG0739@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG5640@2|Bacteria,2G8C6@200795|Chloroflexi,377AX@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M4 thermolysin	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
CMS2_k127_1183366_16	2340.JV46_09570	2.062e-66	231.0	COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,1J7B4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS2_k127_1183366_28	1123392.AQWL01000007_gene1018	4.677e-14	75.0	2ERQZ@1|root,33JA7@2|Bacteria,1NP63@1224|Proteobacteria,2VXN1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YqjK-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YqjK
CMS2_k127_1183366_26	1123392.AQWL01000007_gene1017	4.543e-27	114.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,1KRW7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
CMS2_k127_1183366_24	583345.Mmol_0027	3.39e-29	119.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,2KNZ1@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
CMS2_k127_1183366_21	1123393.KB891326_gene35	1.133e-38	149.0	COG0491@1|root,COG0491@2|Bacteria,1NMU0@1224|Proteobacteria,2WBU4@28216|Betaproteobacteria,1KSJV@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1183366_30	1123393.KB891326_gene35	3.251e-12	68.0	COG0491@1|root,COG0491@2|Bacteria,1NMU0@1224|Proteobacteria,2WBU4@28216|Betaproteobacteria,1KSJV@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1183366_7	1121939.L861_22695	1.148e-121	393.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XH2F@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS2_k127_1183366_2	472759.Nhal_2027	1.396e-178	575.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,1RS1G@1236|Gammaproteobacteria,1WXVJ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_1183366_27	768671.ThimaDRAFT_3598	7.872e-19	89.0	2E0R6@1|root,32W9H@2|Bacteria,1N4U9@1224|Proteobacteria,1SC7F@1236|Gammaproteobacteria,1WZ37@135613|Chromatiales	135613|Chromatiales	S	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
CMS2_k127_1183366_22	1469607.KK073769_gene5336	1.204e-37	146.0	COG0666@1|root,COG0666@2|Bacteria,1GE6V@1117|Cyanobacteria,1HNBU@1161|Nostocales	1117|Cyanobacteria	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4
CMS2_k127_1183366_9	1049564.TevJSym_bf00250	5.736e-104	360.0	COG2304@1|root,COG3509@1|root,COG4257@1|root,COG2304@2|Bacteria,COG3509@2|Bacteria,COG4257@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1J904@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,FG-GAP_2
CMS2_k127_1228718_22	926560.KE387023_gene2289	5.87e-24	117.0	COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS2_k127_1228718_16	330214.NIDE0545	2.472e-49	196.0	COG0745@1|root,COG2202@1|root,COG3290@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GGDEF,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE,dCache_1
CMS2_k127_1228718_10	1116472.MGMO_141c00030	3.702e-71	249.0	COG3409@1|root,COG3409@2|Bacteria,1RJYN@1224|Proteobacteria,1S6DC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
CMS2_k127_1228718_9	314345.SPV1_05168	3.197e-73	252.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria	1224|Proteobacteria	FJ	deaminase	cdd	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CMS2_k127_1228718_23	395495.Lcho_4019	2.255e-16	79.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2VQ6Y@28216|Betaproteobacteria,1KNHV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1228718_11	765910.MARPU_00075	2.658e-70	248.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,1S5PI@1236|Gammaproteobacteria,1WYB8@135613|Chromatiales	135613|Chromatiales	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
CMS2_k127_1228718_6	1123401.JHYQ01000047_gene162	2.882e-84	283.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1S8DJ@1236|Gammaproteobacteria,463PP@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
CMS2_k127_1228718_12	748247.AZKH_1544	3.868e-64	223.0	COG1846@1|root,COG1846@2|Bacteria,1RIX7@1224|Proteobacteria,2VUFV@28216|Betaproteobacteria,2KX57@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS2_k127_1228718_1	748247.AZKH_1543	4.83e-180	571.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VHE6@28216|Betaproteobacteria,2KVS3@206389|Rhodocyclales	206389|Rhodocyclales	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS2_k127_1228718_15	1121405.dsmv_0583	4.288e-54	201.0	COG2199@1|root,COG3706@2|Bacteria,1MYMC@1224|Proteobacteria,42TAS@68525|delta/epsilon subdivisions,2WP1X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GGDEF
CMS2_k127_1228718_2	748280.NH8B_2959	6.38e-178	565.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,2KPWM@206351|Neisseriales	206351|Neisseriales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS2_k127_1228718_3	497321.C664_14084	2.303e-162	518.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,2KV68@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS2_k127_1228718_5	270374.MELB17_16393	1.47e-96	325.0	COG2865@1|root,COG2865@2|Bacteria,1RDDZ@1224|Proteobacteria,1S277@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1228718_20	1163617.SCD_n00500	2.706e-33	133.0	COG3255@1|root,COG3255@2|Bacteria,1N93W@1224|Proteobacteria,2WHTH@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
CMS2_k127_1228718_14	857087.Metme_1250	4.163e-57	211.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S3VR@1236|Gammaproteobacteria,1XDX1@135618|Methylococcales	135618|Methylococcales	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
CMS2_k127_1228718_7	1122599.AUGR01000006_gene3722	4.882e-75	258.0	COG0565@1|root,COG0565@2|Bacteria,1QVUG@1224|Proteobacteria,1T2J9@1236|Gammaproteobacteria,1XS1I@135619|Oceanospirillales	135619|Oceanospirillales	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CMS2_k127_1228718_18	1121035.AUCH01000012_gene2994	1.039e-40	157.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria,2KYU8@206389|Rhodocyclales	206389|Rhodocyclales	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
CMS2_k127_1228718_17	1255043.TVNIR_1758	1.777e-44	163.0	COG2920@1|root,COG2920@2|Bacteria,1N3YM@1224|Proteobacteria	1224|Proteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS2_k127_1228718_8	1123392.AQWL01000005_gene3062	2.094e-73	256.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,1KRVT@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
CMS2_k127_1228718_4	1123393.KB891316_gene1651	1.829e-120	394.0	COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,2VK62@28216|Betaproteobacteria,1KSN8@119069|Hydrogenophilales	119069|Hydrogenophilales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS2_k127_1228718_0	765912.Thimo_1547	0.0	1168.0	COG0021@1|root,COG0176@1|root,COG0021@2|Bacteria,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,1T2QT@1236|Gammaproteobacteria,1WWCJ@135613|Chromatiales	135613|Chromatiales	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.1,2.2.1.2	ko:K00615,ko:K00616	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01827,R01830,R06590	RC00032,RC00226,RC00439,RC00571,RC00604,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N
CMS2_k127_1228718_13	330214.NIDE1441	1.219e-58	216.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	nia	-	1.8.3.1	ko:K00387	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00533	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS2_k127_1228718_21	1163617.SCD_n02062	5.512e-28	117.0	COG2920@1|root,COG2920@2|Bacteria,1NAQC@1224|Proteobacteria,2VWA3@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS2_k127_1228718_24	1123368.AUIS01000005_gene353	1.629e-11	70.0	28XT8@1|root,2ZJPP@2|Bacteria,1P53A@1224|Proteobacteria,1SVUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3330
CMS2_k127_123980_25	886293.Sinac_0089	1.849e-08	66.0	COG0501@1|root,COG0501@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS2_k127_123980_8	572477.Alvin_2660	6.755e-109	361.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales	135613|Chromatiales	S	Methyltransferase	-	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
CMS2_k127_123980_3	1123393.KB891316_gene2017	2.372e-174	557.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,1KS6F@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS2_k127_123980_19	653733.Selin_2194	1.096e-52	192.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS2_k127_123980_4	398767.Glov_0065	2.387e-155	501.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	PFAM aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_123980_16	1033802.SSPSH_001138	2.592e-64	226.0	COG0778@1|root,COG0778@2|Bacteria,1RBZQ@1224|Proteobacteria,1S328@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase	drgA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_123980_17	1123368.AUIS01000019_gene1230	1.317e-57	206.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_16815	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS2_k127_123980_22	1049564.TevJSym_ax00350	8.381e-28	113.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SCFA@1236|Gammaproteobacteria,1J6VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
CMS2_k127_123980_14	765912.Thimo_0112	5.038e-67	230.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria,1WXZR@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_123980_18	1049564.TevJSym_ak00290	1.219e-54	197.0	COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,1S5W4@1236|Gammaproteobacteria,1J7C6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	OU	NfeD-like C-terminal, partner-binding	ybbJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
CMS2_k127_123980_6	857087.Metme_0294	1.065e-139	449.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1XEH8@135618|Methylococcales	135618|Methylococcales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
CMS2_k127_123980_2	1232437.KL661978_gene3781	1.689e-246	801.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,1RJUD@1224|Proteobacteria,42P27@68525|delta/epsilon subdivisions,2WK9Y@28221|Deltaproteobacteria,2MJZE@213118|Desulfobacterales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_8,TonB_dep_Rec,zinc_ribbon_4
CMS2_k127_123980_5	1131553.JIBI01000018_gene517	7.061e-150	501.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,371Z5@32003|Nitrosomonadales	28216|Betaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS2_k127_123980_15	472759.Nhal_3549	6.124e-67	236.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1WYN6@135613|Chromatiales	135613|Chromatiales	K	SMART cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_123980_9	395493.BegalDRAFT_1010	3.033e-106	350.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,45ZYE@72273|Thiotrichales	72273|Thiotrichales	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
CMS2_k127_123980_10	653733.Selin_0426	6.047e-78	270.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS2_k127_123980_11	396595.TK90_2264	5.562e-77	270.0	COG1560@1|root,COG1560@2|Bacteria,1N9ZJ@1224|Proteobacteria,1RRI7@1236|Gammaproteobacteria,1X2ER@135613|Chromatiales	135613|Chromatiales	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.243	ko:K02560	ko00540,ko01100,map00540,map01100	M00060	R05075	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS2_k127_123980_7	1249627.D779_3818	6.212e-115	377.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales	135613|Chromatiales	G	PFAM Fructosamine	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CMS2_k127_123980_23	396588.Tgr7_2979	1.184e-17	87.0	COG2346@1|root,COG2346@2|Bacteria,1RIHJ@1224|Proteobacteria	1224|Proteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS2_k127_123980_13	1487953.JMKF01000027_gene1488	2.654e-68	238.0	COG3576@1|root,COG3576@2|Bacteria,1G5D9@1117|Cyanobacteria,1HAHC@1150|Oscillatoriales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS2_k127_123980_1	187272.Mlg_2496	9.064e-262	826.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS2_k127_123980_0	1049564.TevJSym_ak00590	2.294e-288	895.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1J5IS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS2_k127_123980_20	1121374.KB891577_gene3144	1.942e-35	144.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Cell division protein	ftsN	-	-	ko:K03591	-	-	-	-	ko00000,ko03036	-	-	-	SPOR
CMS2_k127_123980_12	1397528.Q671_00945	3.521e-72	250.0	COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria,1XK02@135619|Oceanospirillales	135619|Oceanospirillales	S	Peptidase membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS2_k127_1255430_3	1123399.AQVE01000006_gene3564	6.835e-32	124.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	COG1051 ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_1255430_0	519989.ECTPHS_01754	6.863e-163	519.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1WWKJ@135613|Chromatiales	135613|Chromatiales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS2_k127_1255430_4	1163617.SCD_n00784	7.207e-30	126.0	2CDCV@1|root,308Y1@2|Bacteria,1N74F@1224|Proteobacteria,2VSMP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1255430_2	322710.Avin_24750	2.087e-79	271.0	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase	nfnB	GO:0000166,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018545,GO:0018973,GO:0018974,GO:0019326,GO:0019439,GO:0032553,GO:0036094,GO:0042537,GO:0042802,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046256,GO:0046260,GO:0046263,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072490,GO:0072491,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_0668,iEcSMS35_1347.EcSMS35_0596,iJN746.PP_2432	Nitroreductase
CMS2_k127_1255430_1	118005.AWNK01000003_gene2312	1.399e-85	294.0	COG1793@1|root,COG1793@2|Bacteria	2|Bacteria	L	dna ligase	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
CMS2_k127_1292834_12	448385.sce9147	3.077e-46	171.0	2CHIC@1|root,2ZNB5@2|Bacteria,1RBRG@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2452)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2452
CMS2_k127_1292834_15	472759.Nhal_2149	2.769e-28	119.0	COG1531@1|root,COG1531@2|Bacteria,1N7PM@1224|Proteobacteria,1SRSR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	AJ	Protein of unknown function (DUF504)	-	-	-	-	-	-	-	-	-	-	-	-	DUF504
CMS2_k127_1292834_3	472759.Nhal_2148	6.985e-120	394.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
CMS2_k127_1292834_9	472759.Nhal_1890	1.187e-52	193.0	COG1818@1|root,COG1818@2|Bacteria,1NEZ5@1224|Proteobacteria	1224|Proteobacteria	S	THUMP	-	-	-	-	-	-	-	-	-	-	-	-	THUMP
CMS2_k127_1292834_14	472759.Nhal_2247	3.628e-30	121.0	2E9MH@1|root,333U5@2|Bacteria,1NDRZ@1224|Proteobacteria,1STW7@1236|Gammaproteobacteria,1X1JP@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1292834_8	243233.MCA2827	1.749e-59	212.0	COG2236@1|root,COG2236@2|Bacteria,1RKB0@1224|Proteobacteria,1S7J1@1236|Gammaproteobacteria,1XFMX@135618|Methylococcales	135618|Methylococcales	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS2_k127_1292834_6	1121921.KB898707_gene1039	4.087e-65	236.0	2CEW9@1|root,2ZAHY@2|Bacteria,1R5J3@1224|Proteobacteria,1S1BX@1236|Gammaproteobacteria,2PN5R@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
CMS2_k127_1292834_0	349521.HCH_06867	0.0	1186.0	COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,1XRXC@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
CMS2_k127_1292834_7	1123228.AUIH01000003_gene874	1.321e-61	219.0	28P60@1|root,2ZC0V@2|Bacteria,1RC8V@1224|Proteobacteria,1S29Y@1236|Gammaproteobacteria,1XJ90@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
CMS2_k127_1292834_2	1397527.Q670_16230	2.735e-149	487.0	28HNB@1|root,2Z7WM@2|Bacteria,1MWQ1@1224|Proteobacteria,1RZ55@1236|Gammaproteobacteria,1XITS@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1292834_13	243233.MCA2737	2.386e-34	139.0	2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SHAU@1236|Gammaproteobacteria,1XFBV@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1292834_5	1049564.TevJSym_ac00950	7.215e-69	239.0	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1J6IC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin	VP2116	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	DSBA,Thioredoxin_5
CMS2_k127_1292834_10	1150621.SMUL_0076	2.911e-49	183.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,42TC2@68525|delta/epsilon subdivisions,2YPKS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
CMS2_k127_1292834_1	472759.Nhal_1498	2.44e-213	686.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
CMS2_k127_1292834_11	523791.Kkor_0110	4.73e-47	185.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RZBU@1236|Gammaproteobacteria,1XNYG@135619|Oceanospirillales	135619|Oceanospirillales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS2_k127_1292834_4	626887.J057_15685	8.702e-80	274.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria,466HZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	ZIP Zinc transporter	zupT	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	iECIAI39_1322.ECIAI39_3536	Zip
CMS2_k127_1304317_1	472759.Nhal_2460	1.599e-227	732.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS2_k127_1304317_3	472759.Nhal_2459	5.01e-139	456.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales	135613|Chromatiales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS2_k127_1304317_2	1049564.TevJSym_ba00130	3.398e-171	546.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1J54A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS2_k127_1304317_10	287.DR97_4288	7.115e-67	240.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1YD77@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_1596,iSDY_1059.SDY_0191	CTP_transf_1
CMS2_k127_1304317_8	395493.BegalDRAFT_3263	1.168e-99	331.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,460AI@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS2_k127_1304317_9	391615.ABSJ01000026_gene144	5.681e-77	261.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1J5ZJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS2_k127_1304317_7	1123073.KB899241_gene3375	6.767e-104	342.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1X4J2@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS2_k127_1304317_5	395493.BegalDRAFT_3260	5.451e-115	377.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,45ZY5@72273|Thiotrichales	72273|Thiotrichales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS2_k127_1304317_6	765914.ThisiDRAFT_1080	5.075e-114	372.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1WW47@135613|Chromatiales	135613|Chromatiales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS2_k127_1304317_4	472759.Nhal_2451	3.846e-133	427.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1WX9V@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS2_k127_1304317_0	187272.Mlg_1865	0.0	1014.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales	135613|Chromatiales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
CMS2_k127_1417028_28	697282.Mettu_2876	5.006e-20	91.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1XDJ1@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS2_k127_1417028_1	1249627.D779_3319	5.324e-285	888.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales	135613|Chromatiales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS2_k127_1417028_16	1049564.TevJSym_av00050	3.676e-82	278.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS2_k127_1417028_30	322710.Avin_36740	7.637e-17	82.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS2_k127_1417028_2	572477.Alvin_1844	8.263e-248	779.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales	135613|Chromatiales	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS2_k127_1417028_3	697282.Mettu_1490	6.147e-237	741.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XEM6@135618|Methylococcales	135618|Methylococcales	F	Thymidine phosphorylase	-	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS2_k127_1417028_11	686340.Metal_2098	3.666e-101	338.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1XDIV@135618|Methylococcales	135618|Methylococcales	F	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
CMS2_k127_1417028_20	1163617.SCD_n00188	1.036e-64	228.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
CMS2_k127_1417028_8	396588.Tgr7_1140	1.943e-122	403.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1WWKH@135613|Chromatiales	135613|Chromatiales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_1417028_31	743299.Acife_1822	3.707e-14	78.0	COG0680@1|root,COG0680@2|Bacteria,1NGWH@1224|Proteobacteria,1SEHF@1236|Gammaproteobacteria,2NDAR@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
CMS2_k127_1417028_5	380394.Lferr_1055	1.583e-193	612.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,2NCF3@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
CMS2_k127_1417028_10	765914.ThisiDRAFT_0873	5.554e-120	389.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Coenzyme F420-reducing hydrogenase, gamma subunit	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
CMS2_k127_1417028_7	1123393.KB891327_gene483	1.345e-123	401.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2VSRF@28216|Betaproteobacteria,1KSI0@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
CMS2_k127_1417028_6	1255043.TVNIR_2172	9.03e-136	442.0	COG1152@1|root,COG1152@2|Bacteria,1QX31@1224|Proteobacteria,1T35A@1236|Gammaproteobacteria,1X2UN@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
CMS2_k127_1417028_29	243159.AFE_3282	7.753e-19	93.0	2DNYF@1|root,32ZSU@2|Bacteria,1N8ZB@1224|Proteobacteria,1S5ZH@1236|Gammaproteobacteria,2NE4S@225057|Acidithiobacillales	225057|Acidithiobacillales	S	HupH hydrogenase expression protein, C-terminal conserved region	-	-	-	ko:K03618	-	-	-	-	ko00000	-	-	-	HupH_C
CMS2_k127_1417028_19	1049564.TevJSym_ai00430	8.424e-65	228.0	COG0745@1|root,COG0745@2|Bacteria,1RBJ1@1224|Proteobacteria,1S4AS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_1417028_24	1304883.KI912532_gene2581	8.597e-41	156.0	2BGQ8@1|root,32AP7@2|Bacteria,1RHYY@1224|Proteobacteria,2VSYN@28216|Betaproteobacteria,2KWTW@206389|Rhodocyclales	206389|Rhodocyclales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS2_k127_1417028_4	1123368.AUIS01000019_gene1224	1.583e-209	665.0	COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1R3QQ@1224|Proteobacteria,1RPFS@1236|Gammaproteobacteria,2NC05@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
CMS2_k127_1417028_22	1108045.GORHZ_217_00230	2.191e-53	190.0	2AHT8@1|root,3185S@2|Bacteria,2IMSB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1417028_13	1163617.SCD_n02203	6.224e-94	315.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,2VQJE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
CMS2_k127_1417028_26	1049564.TevJSym_ak00450	8.361e-37	142.0	COG3118@1|root,COG3118@2|Bacteria,1RI6E@1224|Proteobacteria,1S8B4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	Thioredoxin
CMS2_k127_1417028_21	631362.Thi970DRAFT_03134	6.786e-58	222.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1SJP8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS,PAS_3,PAS_4,PAS_9
CMS2_k127_1417028_12	1163617.SCD_n02290	1.877e-94	336.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
CMS2_k127_1417028_32	1121940.AUDZ01000014_gene1282	1.102e-13	75.0	2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria,1XMMT@135619|Oceanospirillales	135619|Oceanospirillales	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
CMS2_k127_1417028_27	2340.JV46_24320	4.29e-21	97.0	COG0298@1|root,COG0298@2|Bacteria,1QKV6@1224|Proteobacteria,1SE6V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	TIGRFAM hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
CMS2_k127_1417028_25	1049564.TevJSym_bc00320	9.081e-40	152.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
CMS2_k127_1417028_34	395493.BegalDRAFT_2380	3.899e-06	48.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,45ZXH@72273|Thiotrichales	72273|Thiotrichales	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
CMS2_k127_1417028_0	396588.Tgr7_0817	0.0	1416.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS2_k127_1417028_14	1123368.AUIS01000019_gene1207	3.027e-92	308.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,2NCT4@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_1417028_9	1123368.AUIS01000019_gene1206	3.703e-121	405.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,2NCE0@225057|Acidithiobacillales	225057|Acidithiobacillales	T	His Kinase A (phospho-acceptor) domain	-	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS2_k127_1417028_17	472759.Nhal_2317	6.276e-71	247.0	COG0204@1|root,COG0204@2|Bacteria,1PDUQ@1224|Proteobacteria,1S51R@1236|Gammaproteobacteria,1X1S0@135613|Chromatiales	135613|Chromatiales	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_1417028_18	1123368.AUIS01000001_gene1957	2.648e-70	241.0	COG0242@1|root,COG0242@2|Bacteria,1QM3A@1224|Proteobacteria,1RZHN@1236|Gammaproteobacteria,2NC4U@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS2_k127_1417028_23	1249627.D779_1502	2.14e-52	190.0	COG2716@1|root,COG2716@2|Bacteria,1RB6J@1224|Proteobacteria,1S2A4@1236|Gammaproteobacteria,1WXZM@135613|Chromatiales	135613|Chromatiales	E	PFAM Amino acid-binding ACT	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
CMS2_k127_1417028_15	396588.Tgr7_0816	3.598e-92	308.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1WX0I@135613|Chromatiales	135613|Chromatiales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS2_k127_1467352_18	1178482.BJB45_02100	2.165e-38	147.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	enzyme involved in biosynthesis of extracellular polysaccharides	yqjZ	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS2_k127_1467352_4	377629.TERTU_3363	3.758e-134	433.0	COG1075@1|root,COG1075@2|Bacteria,1P9JY@1224|Proteobacteria,1RYH4@1236|Gammaproteobacteria,2PQ8G@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1467352_12	1121015.N789_01070	3.302e-52	200.0	2CEJ2@1|root,32T40@2|Bacteria,1N46C@1224|Proteobacteria,1SATU@1236|Gammaproteobacteria,1X6N7@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4785
CMS2_k127_1467352_10	1123400.KB904748_gene361	1.121e-55	201.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,460UC@72273|Thiotrichales	72273|Thiotrichales	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS2_k127_1467352_0	1283300.ATXB01000002_gene2883	1.83e-303	946.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,1XDNS@135618|Methylococcales	135618|Methylococcales	C	PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS2_k127_1467352_7	1123399.AQVE01000011_gene1230	6.453e-101	338.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor XdhC CoxF family	xdhC2	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS2_k127_1467352_17	1123392.AQWL01000010_gene2306	3.338e-44	168.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VSIN@28216|Betaproteobacteria,1KRTP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS2_k127_1467352_22	395019.Bmul_0471	7.406e-07	56.0	2927F@1|root,2ZPS5@2|Bacteria,1N5W4@1224|Proteobacteria,2WDN3@28216|Betaproteobacteria,1KAMU@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1467352_14	349124.Hhal_1059	1.799e-46	173.0	COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria,1SB8U@1236|Gammaproteobacteria,1WZ0K@135613|Chromatiales	135613|Chromatiales	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.17	ko:K01518	ko00230,ko00240,map00230,map00240	-	R00184,R00969,R01232,R02805	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS2_k127_1467352_3	1056512.D515_03485	3.399e-175	555.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XV1B@135623|Vibrionales	135623|Vibrionales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS2_k127_1467352_1	1042377.AFPJ01000005_gene2457	5.554e-302	942.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4655N@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0210 Superfamily I DNA and RNA helicases	uvrD	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS2_k127_1467352_11	1163617.SCD_n01573	7.141e-53	188.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS2_k127_1467352_13	1163617.SCD_n01142	2.99e-47	180.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CMS2_k127_1467352_16	1123392.AQWL01000004_gene2727	1.671e-44	168.0	COG0526@1|root,COG0526@2|Bacteria,1PHN8@1224|Proteobacteria,2W9SP@28216|Betaproteobacteria,1KSFG@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS2_k127_1467352_8	488538.SAR116_1471	6.256e-81	278.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
CMS2_k127_1467352_2	1349767.GJA_2165	5.001e-232	724.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,2W0HG@28216|Betaproteobacteria,4727U@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4478)	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
CMS2_k127_1467352_15	1229485.AMYV01000103_gene2124	1.426e-45	173.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1PQ4S@1224|Proteobacteria,1TAC0@1236|Gammaproteobacteria,1JBGW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0149)	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C,UPF0149
CMS2_k127_1467352_9	929558.SMGD1_1848	1.212e-73	261.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2YM84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
CMS2_k127_1467352_5	870187.Thini_1080	2.061e-112	370.0	COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_1467352_6	1049564.TevJSym_ab00680	1.948e-107	353.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1J4EP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0246 family	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
CMS2_k127_1467352_19	1085623.GNIT_0678	7.544e-35	139.0	29XEE@1|root,30J4K@2|Bacteria,1P813@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1467352_20	886293.Sinac_2341	1.907e-16	87.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	MA20_24125	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS2_k127_1467352_21	765913.ThidrDRAFT_1661	4.489e-07	54.0	COG0724@1|root,COG0724@2|Bacteria,1P27V@1224|Proteobacteria,1SRKC@1236|Gammaproteobacteria,1X1B5@135613|Chromatiales	135613|Chromatiales	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS2_k127_1467352_23	1394176.AWUO01000014_gene641	0.0002187	46.0	2DR0D@1|root,339ND@2|Bacteria,2GXFZ@201174|Actinobacteria,4D1Q4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1468230_1	743299.Acife_3131	1.162e-113	379.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,2NDPM@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Stress responsive A/B Barrel Domain	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	Dabb,F_bP_aldolase
CMS2_k127_1468230_6	1123368.AUIS01000003_gene1802	2.828e-08	60.0	2EFUG@1|root,339KM@2|Bacteria,1NGQQ@1224|Proteobacteria,1SHZI@1236|Gammaproteobacteria,2ND62@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Alanine-zipper, major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Alanine_zipper
CMS2_k127_1468230_0	1123368.AUIS01000007_gene2702	2.815e-119	391.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,2NCX3@225057|Acidithiobacillales	225057|Acidithiobacillales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
CMS2_k127_1468230_2	768671.ThimaDRAFT_3963	6.973e-97	322.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1WWHE@135613|Chromatiales	135613|Chromatiales	L	hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS2_k127_1468230_3	269799.Gmet_2612	8.91e-60	211.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,430GK@68525|delta/epsilon subdivisions,2WVVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS2_k127_164440_15	522306.CAP2UW1_2680	6.969e-33	128.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,2VWUS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE-2	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS2_k127_164440_9	697282.Mettu_0381	3.357e-83	286.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria,1XEY5@135618|Methylococcales	135618|Methylococcales	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS2_k127_164440_16	1288826.MSNKSG1_00546	2.722e-32	127.0	2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
CMS2_k127_164440_14	472759.Nhal_2241	6.127e-38	150.0	COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	epsilon subunit	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CMS2_k127_164440_1	1415778.JQMM01000001_gene2175	3.342e-233	729.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS2_k127_164440_17	187272.Mlg_2431	3.249e-28	116.0	2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,1SD5T@1236|Gammaproteobacteria,1X269@135613|Chromatiales	135613|Chromatiales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS2_k127_164440_8	1123392.AQWL01000003_gene172	7.687e-102	345.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,1KRS1@119069|Hydrogenophilales	119069|Hydrogenophilales	P	NnrS protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
CMS2_k127_164440_19	1127673.GLIP_4233	0.0004981	44.0	COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,467WZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
CMS2_k127_164440_0	523791.Kkor_1356	6.891e-266	839.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHBW@135619|Oceanospirillales	135619|Oceanospirillales	P	P-type ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS2_k127_164440_13	765914.ThisiDRAFT_1977	3.634e-41	157.0	COG3154@1|root,COG3154@2|Bacteria	2|Bacteria	-	-	yhbT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	MDMPI_C,MDMPI_N,SCP2
CMS2_k127_164440_7	338969.Rfer_0135	1.866e-108	359.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria,4ACI9@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
CMS2_k127_164440_3	1123368.AUIS01000008_gene2168	1.845e-146	470.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,2NCHS@225057|Acidithiobacillales	225057|Acidithiobacillales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CMS2_k127_164440_4	1049564.TevJSym_be00050	1.777e-141	454.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,1RP94@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	radical SAM protein	yhcC	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
CMS2_k127_164440_10	2340.JV46_10510	2.578e-75	258.0	COG0535@1|root,COG0535@2|Bacteria,1QUQ6@1224|Proteobacteria,1T20T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
CMS2_k127_164440_2	1123368.AUIS01000008_gene2170	1.839e-155	499.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,1TD9U@1236|Gammaproteobacteria,2NCIW@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS2_k127_164440_5	713586.KB900536_gene2236	8.858e-128	421.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,1T4ST@1236|Gammaproteobacteria,1WW05@135613|Chromatiales	135613|Chromatiales	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_164440_18	713586.KB900536_gene2237	1.925e-18	88.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	ko:K08363	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	DUF2249,TusA
CMS2_k127_164440_12	713586.KB900536_gene2238	1.173e-50	184.0	COG3945@1|root,COG3945@2|Bacteria,1N383@1224|Proteobacteria,1S89I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Hemerythrin HHE	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS2_k127_164440_6	713586.KB900536_gene465	1.149e-121	398.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales	135613|Chromatiales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS2_k127_164440_11	713586.KB900536_gene644	9.427e-54	191.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1SA44@1236|Gammaproteobacteria,1X24M@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS2_k127_17539_1	1128421.JAGA01000002_gene366	5.432e-82	281.0	COG0796@1|root,COG0796@2|Bacteria,2NP3D@2323|unclassified Bacteria	2|Bacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CMS2_k127_17539_3	29581.BW37_03892	1.535e-47	173.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS2_k127_17539_5	694429.Pyrfu_1674	3.835e-07	57.0	COG0111@1|root,arCOG01754@2157|Archaea,2XSQK@28889|Crenarchaeota	28889|Crenarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS2_k127_17539_0	653733.Selin_0986	2.441e-178	567.0	COG2081@1|root,COG2081@2|Bacteria	2|Bacteria	N	HI0933 family	yhiN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS2_k127_17539_2	870187.Thini_2937	6.061e-67	233.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,462M4@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1415)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1415
CMS2_k127_17539_4	1123366.TH3_04234	9.552e-41	156.0	COG2258@1|root,COG2258@2|Bacteria,1PVVH@1224|Proteobacteria,2UNAM@28211|Alphaproteobacteria,2JYAB@204441|Rhodospirillales	204441|Rhodospirillales	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS2_k127_1776935_0	243231.GSU2657	4.896e-156	508.0	COG2132@1|root,COG5263@1|root,COG2132@2|Bacteria,COG5263@2|Bacteria,1MU0J@1224|Proteobacteria,42QJP@68525|delta/epsilon subdivisions,2WMET@28221|Deltaproteobacteria,43UGS@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Multicopper oxidase	ompC	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2
CMS2_k127_1776935_3	1232410.KI421421_gene3694	1.264e-54	200.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS2_k127_1776935_1	580332.Slit_1812	2.808e-85	304.0	COG2010@1|root,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,2VPYX@28216|Betaproteobacteria,44W5W@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_1776935_5	1349822.NSB1T_14330	2.253e-23	108.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,2FNCK@200643|Bacteroidia,22W5R@171551|Porphyromonadaceae	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fklB	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS2_k127_1776935_4	1121904.ARBP01000003_gene6288	4.954e-29	123.0	2CDK4@1|root,3428Y@2|Bacteria,4P4YE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1776935_2	283699.D172_2488	4.011e-82	275.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,2Q2H3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Integrase core domain	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
CMS2_k127_1794573_0	1123229.AUBC01000013_gene2514	3.387e-191	612.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,2TW8J@28211|Alphaproteobacteria,3K6XK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
CMS2_k127_1794573_2	270374.MELB17_13282	1.064e-51	188.0	COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,1SGQS@1236|Gammaproteobacteria,46C17@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
CMS2_k127_1794573_3	301.JNHE01000004_gene1632	2.185e-13	76.0	2E41E@1|root,32YY1@2|Bacteria,1N86P@1224|Proteobacteria,1T0I3@1236|Gammaproteobacteria,1YKXM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
CMS2_k127_1794573_1	1116472.MGMO_96c00150	1.651e-83	285.0	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria,1XFER@135618|Methylococcales	135618|Methylococcales	M	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
CMS2_k127_1897027_42	323261.Noc_2830	4.086e-20	93.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,1SGEP@1236|Gammaproteobacteria,1X1XT@135613|Chromatiales	135613|Chromatiales	S	PFAM VanZ	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS2_k127_1897027_33	870187.Thini_2789	2.869e-46	177.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
CMS2_k127_1897027_1	42565.FP66_14315	1.123e-266	847.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
CMS2_k127_1897027_34	243233.MCA2786	2.5e-45	168.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,1XF88@135618|Methylococcales	135618|Methylococcales	S	PFAM SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
CMS2_k127_1897027_32	396588.Tgr7_0365	4.812e-47	171.0	COG2920@1|root,COG2920@2|Bacteria	2|Bacteria	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS2_k127_1897027_2	768671.ThimaDRAFT_3655	1.241e-256	809.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1WW3V@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
CMS2_k127_1897027_44	1328313.DS2_08625	4.569e-08	57.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria,468Y8@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the SlyX family	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
CMS2_k127_1897027_36	329726.AM1_4941	1.197e-34	136.0	COG3450@1|root,COG3450@2|Bacteria,1G7YR@1117|Cyanobacteria	1117|Cyanobacteria	S	of the cupin superfamily	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
CMS2_k127_1897027_3	697282.Mettu_1676	2.951e-253	796.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XEJJ@135618|Methylococcales	135618|Methylococcales	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_1897027_11	2340.JV46_15540	7.859e-130	419.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CMS2_k127_1897027_37	1121085.AUCI01000026_gene2280	1.792e-30	124.0	COG0640@1|root,COG0640@2|Bacteria,1VJC2@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS2_k127_1897027_16	395493.BegalDRAFT_2378	2.388e-101	336.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,460GA@72273|Thiotrichales	72273|Thiotrichales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS2_k127_1897027_31	713586.KB900536_gene2631	7.104e-50	180.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1WYSF@135613|Chromatiales	135613|Chromatiales	P	PFAM ApaG domain protein	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS2_k127_1897027_22	472759.Nhal_3052	1.593e-79	276.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1WW69@135613|Chromatiales	135613|Chromatiales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
CMS2_k127_1897027_28	323261.Noc_1348	4.382e-55	201.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1SYT9@1236|Gammaproteobacteria,1X25R@135613|Chromatiales	135613|Chromatiales	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CMS2_k127_1897027_26	1123399.AQVE01000007_gene1097	7.219e-59	209.0	2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1897027_15	1123020.AUIE01000017_gene3019	7.15e-102	338.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1YEA3@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS2_k127_1897027_9	1134474.O59_003725	7.41e-136	439.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1FFTZ@10|Cellvibrio	1236|Gammaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_0056	PdxA
CMS2_k127_1897027_10	323261.Noc_1723	5.688e-130	428.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales	135613|Chromatiales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
CMS2_k127_1897027_7	713586.KB900536_gene2638	1.168e-159	529.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales	135613|Chromatiales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
CMS2_k127_1897027_24	1095769.CAHF01000006_gene1897	4.219e-70	245.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,2VR7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1897027_13	1049564.TevJSym_ao00360	1.416e-126	413.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1J50Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	related to Ser Thr protein kinases	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
CMS2_k127_1897027_30	396588.Tgr7_2175	2.542e-51	190.0	COG0790@1|root,COG0790@2|Bacteria,1PFSC@1224|Proteobacteria,1TJ65@1236|Gammaproteobacteria,1WY15@135613|Chromatiales	135613|Chromatiales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS2_k127_1897027_18	768671.ThimaDRAFT_1127	7.561e-94	312.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales	135613|Chromatiales	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CMS2_k127_1897027_6	1123368.AUIS01000019_gene1204	1.699e-163	528.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	glutamate--cysteine ligase	ybdK_1	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS2_k127_1897027_12	1123368.AUIS01000019_gene1205	4.708e-128	417.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
CMS2_k127_1897027_29	1046714.AMRX01000006_gene2941	4.578e-53	196.0	2D6GH@1|root,32TM6@2|Bacteria,1NPNC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1897027_5	396588.Tgr7_3291	3.309e-197	620.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1WXIY@135613|Chromatiales	135613|Chromatiales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
CMS2_k127_1897027_40	1116472.MGMO_44c00130	9.439e-26	108.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XFQ2@135618|Methylococcales	135618|Methylococcales	K	SMART Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_1897027_14	523791.Kkor_1737	2.861e-108	352.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XH9F@135619|Oceanospirillales	135619|Oceanospirillales	O	Alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS2_k127_1897027_8	1123368.AUIS01000026_gene1449	5.478e-159	514.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2NBZC@225057|Acidithiobacillales	225057|Acidithiobacillales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_1897027_41	998674.ATTE01000001_gene4531	2.04e-25	109.0	COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,46353@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
CMS2_k127_1897027_21	472759.Nhal_3469	8.272e-80	273.0	COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,1WYCI@135613|Chromatiales	135613|Chromatiales	L	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair	mutH	-	-	ko:K03573	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutH
CMS2_k127_1897027_20	1122134.KB893650_gene874	7.048e-82	287.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,1RNQE@1236|Gammaproteobacteria,1XJRP@135619|Oceanospirillales	135619|Oceanospirillales	C	NADH dehydrogenase NAD(P)H nitroreductase	-	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CMS2_k127_1897027_38	314278.NB231_05801	9.146e-30	121.0	2CECF@1|root,32RZM@2|Bacteria,1N130@1224|Proteobacteria,1S98I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	pilin assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1897027_23	870187.Thini_2017	3.851e-73	249.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,460J4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS2_k127_1897027_43	870187.Thini_2020	5.052e-18	86.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,1S8S1@1236|Gammaproteobacteria,461FN@72273|Thiotrichales	72273|Thiotrichales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS2_k127_1897027_27	697282.Mettu_2395	1.276e-58	207.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1XFC1@135618|Methylococcales	135618|Methylococcales	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
CMS2_k127_1897027_39	1283300.ATXB01000001_gene1949	1.141e-28	121.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,1SAW8@1236|Gammaproteobacteria,1XGQM@135618|Methylococcales	135618|Methylococcales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS2_k127_1897027_25	1049564.TevJSym_at00740	2.38e-66	230.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,1S2YE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS2_k127_1897027_17	1049564.TevJSym_at00750	9.364e-95	313.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1J5R6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iJN746.PP_0538,iPC815.YPO3521	Pyrophosphatase
CMS2_k127_1897027_0	713586.KB900536_gene1465	0.0	1079.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1WVYF@135613|Chromatiales	135613|Chromatiales	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS2_k127_1897027_4	1163617.SCD_n01888	6.633e-234	728.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS2_k127_1897027_35	1049564.TevJSym_by00060	5.084e-35	136.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,1SDCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1897027_19	396588.Tgr7_2713	4.345e-87	304.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS2_k127_1917943_13	1206777.B195_18486	6.598e-97	324.0	COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1Z6XN@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	Transcriptional regulator	cmpR_1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS2_k127_1917943_0	1122201.AUAZ01000008_gene420	1.695e-246	767.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,4642D@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS2_k127_1917943_9	546266.NEIMUCOT_04611	1.588e-113	368.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KPI7@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS2_k127_1917943_5	292415.Tbd_1920	3.212e-184	580.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,1KRIM@119069|Hydrogenophilales	119069|Hydrogenophilales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS2_k127_1917943_3	1163617.SCD_n00876	2.093e-207	649.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_1917943_12	312309.VF_1698	7.937e-101	338.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1XT9P@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS2_k127_1917943_15	396588.Tgr7_1249	4.882e-91	334.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales	135613|Chromatiales	NU	FimV C-terminal	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	TPR_19
CMS2_k127_1917943_11	1027273.GZ77_02190	5.523e-109	359.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1XHYZ@135619|Oceanospirillales	135619|Oceanospirillales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS2_k127_1917943_16	1215092.PA6_027_01090	9.491e-79	271.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1YD0W@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS2_k127_1917943_2	396588.Tgr7_1253	4.521e-217	678.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_1917943_8	713586.KB900536_gene61	9.962e-114	372.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1WXGF@135613|Chromatiales	135613|Chromatiales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS2_k127_1917943_6	1049564.TevJSym_ar00070	4.46e-138	443.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1J4MN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
CMS2_k127_1917943_7	323261.Noc_1023	5.47e-132	434.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1WWQD@135613|Chromatiales	135613|Chromatiales	H	Belongs to the folylpolyglutamate synthase family	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CMS2_k127_1917943_22	519989.ECTPHS_05380	3.035e-25	112.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1WZEE@135613|Chromatiales	135613|Chromatiales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
CMS2_k127_1917943_18	472759.Nhal_3110	2.582e-54	194.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1WY7W@135613|Chromatiales	135613|Chromatiales	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS2_k127_1917943_1	572477.Alvin_1026	1.25e-239	749.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1WWAI@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
CMS2_k127_1917943_4	396588.Tgr7_0930	3.796e-194	613.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1WWGS@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS2_k127_1917943_17	1049564.TevJSym_ar00510	1.567e-66	234.0	COG4106@1|root,COG4106@2|Bacteria,1QWJU@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS2_k127_1917943_10	314278.NB231_00994	3.066e-110	371.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales	135613|Chromatiales	G	pfam mofrl	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS2_k127_1917943_19	1444711.CCJF01000005_gene1177	6.436e-50	191.0	COG3782@1|root,COG3782@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1853)	-	-	-	ko:K09977	-	-	-	-	ko00000	-	-	-	DUF1853
CMS2_k127_1917943_14	396588.Tgr7_0932	4.413e-94	315.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,1WX4Y@135613|Chromatiales	135613|Chromatiales	G	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
CMS2_k127_1917943_21	1049564.TevJSym_aa02160	7.354e-36	145.0	2BXIA@1|root,2ZJ26@2|Bacteria,1P6T0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1917943_23	658187.LDG_6258	2.324e-23	104.0	COG5622@1|root,COG5622@2|Bacteria,1NBBZ@1224|Proteobacteria,1T8NN@1236|Gammaproteobacteria,1JEVZ@118969|Legionellales	118969|Legionellales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS2_k127_1917943_20	1385515.N791_06855	3.885e-41	154.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,1X443@135614|Xanthomonadales	135614|Xanthomonadales	L	Helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
CMS2_k127_1933375_28	1509403.GW12_11570	5.13e-07	59.0	COG0551@1|root,COG0551@2|Bacteria,1PZFI@1224|Proteobacteria,1RQ64@1236|Gammaproteobacteria,3NKDD@468|Moraxellaceae	1236|Gammaproteobacteria	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,zf-C4_Topoisom
CMS2_k127_1933375_2	1049564.TevJSym_an00050	1.324e-239	760.0	COG3221@1|root,COG4191@1|root,COG3221@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1J5WY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	fixL	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS2_k127_1933375_16	765910.MARPU_12465	1.159e-67	238.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1WXDV@135613|Chromatiales	135613|Chromatiales	K	response regulator receiver	-	-	-	ko:K13041	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS2_k127_1933375_0	292415.Tbd_0563	4.28e-261	814.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,1KSXW@119069|Hydrogenophilales	119069|Hydrogenophilales	F	5'-nucleotidase, C-terminal domain	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
CMS2_k127_1933375_1	1163617.SCD_n02338	8.606e-257	807.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,2VPN4@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
CMS2_k127_1933375_18	159087.Daro_3749	4.114e-66	232.0	COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,2VNXB@28216|Betaproteobacteria,2KY2A@206389|Rhodocyclales	206389|Rhodocyclales	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1933375_11	1049564.TevJSym_ac01720	3.739e-127	411.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1J5I0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS2_k127_1933375_26	391615.ABSJ01000002_gene467	7.852e-09	57.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1933375_29	1035839.AFNK01000001_gene433	1.963e-05	47.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1933375_20	697282.Mettu_2751	6.112e-57	207.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,Robl_LC7
CMS2_k127_1933375_24	945543.VIBR0546_20228	1.618e-11	68.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales	135623|Vibrionales	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS2_k127_1933375_4	1163617.SCD_n02614	4.977e-230	723.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VJF0@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
CMS2_k127_1933375_19	1163617.SCD_n02597	5.772e-64	224.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2VRBF@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE9	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_1933375_15	580332.Slit_2772	4.775e-79	269.0	COG4944@1|root,COG4944@2|Bacteria	2|Bacteria	K	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
CMS2_k127_1933375_13	1318628.MARLIPOL_12764	1.752e-113	372.0	COG2204@1|root,COG2207@1|root,COG2204@2|Bacteria,COG2207@2|Bacteria,1N1CY@1224|Proteobacteria,1SBMK@1236|Gammaproteobacteria,46BB9@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,PocR,Response_reg,Sigma54_activ_2
CMS2_k127_1933375_25	1318628.MARLIPOL_12759	7.021e-10	64.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS2_k127_1933375_22	1318628.MARLIPOL_12754	1.556e-53	194.0	COG1989@1|root,COG1989@2|Bacteria,1R34X@1224|Proteobacteria,1SHX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
CMS2_k127_1933375_5	1318628.MARLIPOL_12749	7.486e-221	694.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,1RZBX@1236|Gammaproteobacteria,469JC@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_1933375_14	1318628.MARLIPOL_12744	1.892e-99	331.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,1S6EP@1236|Gammaproteobacteria,46AU1@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Flp pilus assembly protein RcpC/CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS2_k127_1933375_6	1318628.MARLIPOL_12739	1.675e-213	675.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,4683Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the GSP D family	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
CMS2_k127_1933375_7	1318628.MARLIPOL_12729	1.656e-181	575.0	COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,46AQ4@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
CMS2_k127_1933375_21	1318628.MARLIPOL_12724	5.351e-56	199.0	COG4961@1|root,COG4961@2|Bacteria,1NCGE@1224|Proteobacteria,1SDQ1@1236|Gammaproteobacteria,46BYJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS2_k127_1933375_17	1318628.MARLIPOL_12719	4.104e-67	232.0	COG4961@1|root,COG4961@2|Bacteria,1N2QC@1224|Proteobacteria,1SB8M@1236|Gammaproteobacteria,46BJ2@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS2_k127_1933375_8	1318628.MARLIPOL_12714	1.058e-164	526.0	COG2199@1|root,COG4963@1|root,COG3706@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S6CE@1236|Gammaproteobacteria,469IJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
CMS2_k127_1933375_3	1318628.MARLIPOL_12709	1.25e-233	730.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,4644B@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG4962 Flp pilus assembly protein, ATPase CpaF	tadA	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS2_k127_1933375_9	1318628.MARLIPOL_12704	9.428e-147	470.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria,469CH@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Type II secretion system (T2SS), protein F	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS2_k127_1933375_10	1318628.MARLIPOL_12699	1.235e-146	470.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1RTD3@1236|Gammaproteobacteria,468ZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein F	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS2_k127_1933375_12	1318628.MARLIPOL_12694	2.703e-120	394.0	COG0457@1|root,COG0457@2|Bacteria,1PEMT@1224|Proteobacteria,1S5W3@1236|Gammaproteobacteria,468ZA@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
CMS2_k127_2023296_9	316067.Geob_0330	8.175e-14	76.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria,43SWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
CMS2_k127_2023296_6	357804.Ping_0701	4.229e-61	221.0	COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria,1S5D0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
CMS2_k127_2023296_2	1123519.PSJM300_17270	2.014e-110	366.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1Z0T3@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675	RsgA_GTPase
CMS2_k127_2023296_7	1122185.N792_08510	4.098e-29	121.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,1X738@135614|Xanthomonadales	135614|Xanthomonadales	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS2_k127_2023296_8	396588.Tgr7_1079	3.27e-22	99.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SF76@1236|Gammaproteobacteria,1WZJF@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_2023296_0	1123400.KB904813_gene3071	1.661e-157	507.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS2_k127_2023296_4	1123519.PSJM300_17265	1.266e-83	280.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1Z1HG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CMS2_k127_2023296_5	857087.Metme_2909	1.429e-66	232.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XF04@135618|Methylococcales	135618|Methylococcales	S	pfam ammecr1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
CMS2_k127_2023296_3	243233.MCA0072	1.562e-101	338.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1XEER@135618|Methylococcales	135618|Methylococcales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS2_k127_2023296_1	1266909.AUAG01000013_gene709	1.467e-117	383.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS2_k127_2107672_5	335543.Sfum_0365	4.261e-34	145.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MR2J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	MltA specific insert domain	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
CMS2_k127_2107672_4	1123368.AUIS01000024_gene944	1.106e-38	156.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,1S884@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
CMS2_k127_2107672_3	522306.CAP2UW1_1702	3.973e-72	248.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
CMS2_k127_2107672_1	522306.CAP2UW1_1703	1.206e-147	477.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,1KQRX@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_2107672_0	1121035.AUCH01000007_gene444	0.0	1477.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KUKW@206389|Rhodocyclales	206389|Rhodocyclales	V	AcrB/AcrD/AcrF family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS2_k127_2107672_2	395493.BegalDRAFT_1071	6.938e-115	391.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein conserved in bacteria	ycbB	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
CMS2_k127_2107672_7	261292.Nit79A3_1163	5.23e-14	77.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2VRCS@28216|Betaproteobacteria,3737H@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
CMS2_k127_2109456_4	220664.PFL_1174	1.232e-06	50.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1YMTE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
CMS2_k127_2109456_1	396588.Tgr7_1436	1.828e-81	281.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1WVWC@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM RNA polymerase sigma factor RpoS	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_2109456_3	765911.Thivi_0871	3.932e-47	177.0	COG4566@1|root,COG4566@2|Bacteria,1N3YG@1224|Proteobacteria,1S1VP@1236|Gammaproteobacteria,1WXWC@135613|Chromatiales	135613|Chromatiales	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_2109456_6	247490.KSU1_B0412	2.632e-05	53.0	COG4467@1|root,COG4467@2|Bacteria,2J4XJ@203682|Planctomycetes	203682|Planctomycetes	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,zf-IS66
CMS2_k127_2109456_5	1349767.GJA_4257	5.08e-06	54.0	COG4467@1|root,COG4467@2|Bacteria,1QW8C@1224|Proteobacteria	1224|Proteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
CMS2_k127_2109456_2	1122134.KB893650_gene562	7.619e-59	214.0	2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria,1XQ67@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2109456_0	187272.Mlg_1653	6.706e-141	450.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria,1WW7Y@135613|Chromatiales	135613|Chromatiales	C	reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS2_k127_2121358_7	472759.Nhal_0463	9.422e-145	472.0	COG3408@1|root,COG3408@2|Bacteria,1PGVT@1224|Proteobacteria,1SHCY@1236|Gammaproteobacteria,1WZTG@135613|Chromatiales	135613|Chromatiales	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100
CMS2_k127_2121358_3	247490.KSU1_C1305	0.0	1004.0	COG0296@1|root,COG0296@2|Bacteria,2IXS1@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS2_k127_2121358_4	472759.Nhal_2490	2.778e-309	960.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales	135613|Chromatiales	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
CMS2_k127_2121358_1	472759.Nhal_2491	0.0	1610.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,1RMSH@1236|Gammaproteobacteria,1WY9K@135613|Chromatiales	135613|Chromatiales	G	alpha amylase catalytic	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
CMS2_k127_2121358_6	1283300.ATXB01000001_gene1693	4.534e-185	587.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XGA0@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
CMS2_k127_2121358_2	314278.NB231_16468	0.0	1073.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS2_k127_2121358_5	765912.Thimo_2343	2.86e-252	794.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1RP2N@1236|Gammaproteobacteria,1WWIM@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM malto-oligosyltrehalose trehalohydrolase	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
CMS2_k127_2121358_0	1163617.SCD_n02434	0.0	1825.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,2WGPV@28216|Betaproteobacteria	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	treY	-	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
CMS2_k127_2121358_8	519989.ECTPHS_08301	5.091e-12	65.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1WW21@135613|Chromatiales	135613|Chromatiales	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS2_k127_2122188_12	745411.B3C1_05842	8.831e-113	370.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1J52T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS2_k127_2122188_22	292415.Tbd_2804	0.0001623	49.0	2AFZM@1|root,3163K@2|Bacteria,1PWSR@1224|Proteobacteria,2VYPF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
CMS2_k127_2122188_9	1123392.AQWL01000013_gene2375	4.166e-135	434.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS2_k127_2122188_21	1049564.TevJSym_aq00410	2.09e-34	132.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1J6WA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS2_k127_2122188_15	754476.Q7A_225	8.621e-62	216.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,460SP@72273|Thiotrichales	72273|Thiotrichales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS2_k127_2122188_17	472759.Nhal_3949	2.033e-54	196.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales	135613|Chromatiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS2_k127_2122188_0	1026882.MAMP_00732	2.427e-279	864.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS2_k127_2122188_10	472759.Nhal_3947	1.84e-134	433.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1WW4K@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS2_k127_2122188_2	395493.BegalDRAFT_3131	7.453e-266	822.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,46017@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS2_k127_2122188_16	472759.Nhal_3945	8.463e-59	207.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1WY0Q@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS2_k127_2122188_19	1163617.SCD_n01922	2.23e-48	178.0	COG1047@1|root,COG1047@2|Bacteria,1N0ZF@1224|Proteobacteria,2W2PN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS2_k127_2122188_6	1123020.AUIE01000002_gene1576	8.751e-176	561.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1YDUT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_4420,iYL1228.KPN_04135	Hexapep,Hexapep_2,NTP_transf_3
CMS2_k127_2122188_1	2340.JV46_17470	3.389e-276	860.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1J4EZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281	GATase_6,SIS
CMS2_k127_2122188_18	713587.THITH_06120	9.579e-54	194.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,1S6PD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	PFAM Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,TehB
CMS2_k127_2122188_5	1049564.TevJSym_ag00980	1.808e-217	685.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1J4T7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iPC815.YPO3762,iSFV_1184.SFV_3651	TrkH
CMS2_k127_2122188_4	631362.Thi970DRAFT_00704	8.551e-227	709.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales	135613|Chromatiales	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS2_k127_2122188_7	765911.Thivi_3193	4.874e-158	511.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_2122188_3	713586.KB900536_gene2226	1.264e-230	735.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
CMS2_k127_2122188_20	395493.BegalDRAFT_0740	3.594e-41	162.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,463I0@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
CMS2_k127_2122188_8	1453503.AU05_15085	2.506e-146	475.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1YE4T@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
CMS2_k127_2122188_11	1049564.TevJSym_ag01040	7.747e-120	394.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1J4V0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
CMS2_k127_2122188_14	1049564.TevJSym_ag01050	4.298e-78	263.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1J5V6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS2_k127_2122188_13	1026882.MAMP_00785	2.302e-82	285.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales	72273|Thiotrichales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS2_k127_2123102_3	631362.Thi970DRAFT_02857	5.124e-158	513.0	COG0438@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1QP7Y@1224|Proteobacteria,1RR12@1236|Gammaproteobacteria,1WXJ8@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
CMS2_k127_2123102_0	399795.CtesDRAFT_PD1865	8.241e-230	725.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VJBU@28216|Betaproteobacteria,4AFRQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Polysaccharide biosynthesis/export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
CMS2_k127_2123102_4	399795.CtesDRAFT_PD1864	1.596e-126	416.0	COG3524@1|root,COG3524@2|Bacteria,1R3ZY@1224|Proteobacteria,2WFDA@28216|Betaproteobacteria,4AEVN@80864|Comamonadaceae	28216|Betaproteobacteria	M	COG3524 Capsule polysaccharide export protein	kpsE	-	-	ko:K10107	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101	-	-	-
CMS2_k127_2123102_5	399795.CtesDRAFT_PD1863	5.637e-97	324.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2VHMP@28216|Betaproteobacteria,4ABUQ@80864|Comamonadaceae	28216|Betaproteobacteria	GM	PFAM ABC transporter related	kpsT	-	3.6.3.38	ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101,3.A.1.103	-	-	ABC_tran
CMS2_k127_2123102_8	228410.NE1386	7.048e-78	270.0	COG1682@1|root,COG1682@2|Bacteria,1MUTE@1224|Proteobacteria,2VT6H@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Transport permease protein	-	-	-	ko:K09688	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101	-	-	ABC2_membrane
CMS2_k127_2123102_1	102129.Lepto7375DRAFT_0197	7.402e-192	605.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS2_k127_2123102_9	243233.MCA1262	1.19e-23	105.0	2B301@1|root,31VM8@2|Bacteria,1QTHY@1224|Proteobacteria,1SW46@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2123102_6	626887.J057_17725	1.453e-96	326.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
CMS2_k127_2123102_7	1121943.KB899992_gene2159	8.645e-94	314.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
CMS2_k127_2123102_2	1121943.KB899992_gene2157	8.802e-167	535.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
CMS2_k127_2143539_8	187272.Mlg_1097	2.792e-257	812.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WW1G@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS2_k127_2143539_4	768671.ThimaDRAFT_2664	0.0	1084.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1WWU3@135613|Chromatiales	135613|Chromatiales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
CMS2_k127_2143539_79	1411685.U062_02362	5.538e-13	75.0	2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1J75G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2143539_30	396588.Tgr7_1362	4.812e-135	437.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1WXIP@135613|Chromatiales	135613|Chromatiales	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
CMS2_k127_2143539_23	1123368.AUIS01000006_gene588	7.832e-152	484.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,2NCP9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS2_k127_2143539_48	1469245.JFBG01000012_gene931	7.167e-80	273.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_2143539_32	519989.ECTPHS_02741	1.859e-115	386.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RM90@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_8,PAS_4,Sigma54_activat
CMS2_k127_2143539_13	314285.KT71_09502	2.255e-200	631.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,1J9DV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	sqr	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_2143539_1	472759.Nhal_3142	0.0	1500.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales	135613|Chromatiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS2_k127_2143539_58	713586.KB900536_gene682	5.165e-61	218.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_2143539_73	1163617.SCD_n02803	5.071e-29	119.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
CMS2_k127_2143539_59	631362.Thi970DRAFT_04285	7.498e-61	214.0	COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1WY49@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_2143539_17	265072.Mfla_0652	5.528e-186	592.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,2KKMV@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS2_k127_2143539_57	637905.SVI_0385	1.448e-63	226.0	COG0607@1|root,COG0607@2|Bacteria,1RM2N@1224|Proteobacteria,1S8IB@1236|Gammaproteobacteria,2QD6M@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_2143539_14	1122201.AUAZ01000008_gene484	4.605e-200	631.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,4642I@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
CMS2_k127_2143539_72	396588.Tgr7_2600	1.275e-30	125.0	COG1993@1|root,COG1993@2|Bacteria,1N8TP@1224|Proteobacteria,1SDYH@1236|Gammaproteobacteria,1WZIY@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
CMS2_k127_2143539_65	1049564.TevJSym_ah00210	2.872e-46	169.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1J6UX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS2_k127_2143539_82	573061.Clocel_3797	1.889e-09	65.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,36KID@31979|Clostridiaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS2_k127_2143539_81	1121930.AQXG01000007_gene494	2.795e-10	73.0	COG0776@1|root,COG0776@2|Bacteria,4NQVM@976|Bacteroidetes	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding,LysM
CMS2_k127_2143539_84	686340.Metal_2192	0.0005267	53.0	COG1652@1|root,COG3753@1|root,COG1652@2|Bacteria,COG3753@2|Bacteria,1RD8K@1224|Proteobacteria,1SENI@1236|Gammaproteobacteria,1XFVA@135618|Methylococcales	135618|Methylococcales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
CMS2_k127_2143539_15	754477.Q7C_1650	1.205e-196	623.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,4606R@72273|Thiotrichales	72273|Thiotrichales	L	ATPase (AAA	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS2_k127_2143539_62	640081.Dsui_1692	8.38e-51	187.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,2KWH0@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
CMS2_k127_2143539_6	754477.Q7C_1652	1.9e-284	893.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4604W@72273|Thiotrichales	72273|Thiotrichales	D	cell division protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS2_k127_2143539_27	396588.Tgr7_2005	2.264e-143	463.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1WXVZ@135613|Chromatiales	135613|Chromatiales	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS2_k127_2143539_22	90813.JQMT01000001_gene1269	7.545e-156	499.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,4608I@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_2143539_46	401526.TcarDRAFT_2666	1.031e-87	315.0	COG1368@1|root,COG1368@2|Bacteria,1VRN2@1239|Firmicutes,4H2GG@909932|Negativicutes	909932|Negativicutes	M	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_2143539_74	395493.BegalDRAFT_0787	2.461e-28	117.0	2EBC7@1|root,335CY@2|Bacteria,1NFCS@1224|Proteobacteria,1SDGF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2143539_78	663610.JQKO01000010_gene2144	5.852e-15	81.0	2BKDJ@1|root,32EU8@2|Bacteria,1RKF1@1224|Proteobacteria,2UBM3@28211|Alphaproteobacteria,3NB9T@45404|Beijerinckiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2143539_24	765912.Thimo_2448	1.109e-150	485.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales	135613|Chromatiales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CMS2_k127_2143539_45	472759.Nhal_3735	7.945e-90	301.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1WWJ2@135613|Chromatiales	135613|Chromatiales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS2_k127_2143539_52	1122951.ATUE01000006_gene1227	2.384e-77	265.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,3NJG0@468|Moraxellaceae	1236|Gammaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CMS2_k127_2143539_71	751994.AGIG01000031_gene266	1.216e-36	138.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1J6G9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS2_k127_2143539_5	1415754.JQMK01000002_gene3518	0.0	1075.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,464M6@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS2_k127_2143539_68	566466.NOR53_923	8.018e-45	165.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1J6Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS2_k127_2143539_76	765912.Thimo_2094	6.548e-20	91.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WYWN@135613|Chromatiales	135613|Chromatiales	K	TIGRFAM cold shock domain protein CspD	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_2143539_10	396588.Tgr7_1840	1.508e-229	716.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1WVYY@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
CMS2_k127_2143539_50	1453503.AU05_00230	9.73e-79	268.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,1YDKN@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS2_k127_2143539_64	1123368.AUIS01000006_gene584	9.673e-49	180.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,1S970@1236|Gammaproteobacteria,2NCZI@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS2_k127_2143539_21	498211.CJA_2490	3.321e-160	512.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1FG0P@10|Cellvibrio	1236|Gammaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS2_k127_2143539_60	225937.HP15_2087	3.81e-58	209.0	COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,467AZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	High frequency lysogenization protein HflD homolog	hflD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562	-	ko:K07153	-	-	-	-	ko00000	-	-	-	DUF489
CMS2_k127_2143539_77	935567.JAES01000001_gene2208	4.885e-17	85.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1X84H@135614|Xanthomonadales	135614|Xanthomonadales	L	competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
CMS2_k127_2143539_44	1163617.SCD_n01038	7.033e-91	304.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS2_k127_2143539_38	395493.BegalDRAFT_1798	9.257e-104	349.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,460FI@72273|Thiotrichales	72273|Thiotrichales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
CMS2_k127_2143539_80	1034943.BN1094_03484	4.947e-11	66.0	COG5416@1|root,COG5416@2|Bacteria,1NGPH@1224|Proteobacteria,1SGDB@1236|Gammaproteobacteria,1JERF@118969|Legionellales	118969|Legionellales	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
CMS2_k127_2143539_70	391615.ABSJ01000055_gene1337	1.105e-41	156.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1J6GT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS2_k127_2143539_7	1049564.TevJSym_ad01490	3.62e-284	882.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1J51F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS2_k127_2143539_53	318161.Sden_1752	2.827e-77	265.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,2Q8RS@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO1391,iSDY_1059.SDY_2348	Cytidylate_kin
CMS2_k127_2143539_12	396588.Tgr7_1541	3.924e-211	662.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS2_k127_2143539_36	765911.Thivi_2125	1.125e-104	347.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,1WW2D@135613|Chromatiales	135613|Chromatiales	E	PFAM Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS2_k127_2143539_20	395494.Galf_1142	4.032e-174	550.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VH85@28216|Betaproteobacteria,44VHR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS2_k127_2143539_25	220664.PFL_4311	2.378e-144	467.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1YNT6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_2143539_26	1049564.TevJSym_ad01430	1.156e-143	464.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1J4I4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS2_k127_2143539_18	1049564.TevJSym_ad01420	1.296e-183	580.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1J5JA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS2_k127_2143539_19	2340.JV46_02820	4.525e-182	574.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1J4PA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEcE24377_1341.EcE24377A_1004,iPC815.YPO1389,iYL1228.KPN_00935	Aminotran_5
CMS2_k127_2143539_3	713586.KB900536_gene476	0.0	1315.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1WXK8@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS2_k127_2143539_29	713586.KB900536_gene475	1.945e-137	447.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1WWQU@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS2_k127_2143539_67	870187.Thini_3575	6.64e-45	175.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S06S@1236|Gammaproteobacteria,4632G@72273|Thiotrichales	72273|Thiotrichales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
CMS2_k127_2143539_51	1123279.ATUS01000001_gene2460	9.413e-78	266.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1J5YU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Transcriptional regulatory protein, C terminal	raxR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_2143539_43	292415.Tbd_2610	2.519e-92	318.0	COG0642@1|root,COG2205@2|Bacteria,1QV1H@1224|Proteobacteria,2WGY6@28216|Betaproteobacteria,1KTC9@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_2143539_9	1049564.TevJSym_ab00410	1.845e-232	737.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1J50Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,STAS_2,Sulfate_transp
CMS2_k127_2143539_16	396588.Tgr7_1531	4.224e-187	596.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS2_k127_2143539_31	1049564.TevJSym_ad01360	3.32e-118	383.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1J584@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2376	Methyltransf_23
CMS2_k127_2143539_49	1049564.TevJSym_ad01350	2.25e-79	271.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1J674@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	HAD-hyrolase-like	gph	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006040,GO:0006082,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009254,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0030203,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097172,GO:1901135,GO:1901360,GO:1901564	3.1.3.105,3.1.3.18	ko:K01091,ko:K22292	ko00520,ko00630,ko01100,ko01110,ko01130,map00520,map00630,map01100,map01110,map01130	-	R01334,R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS2_k127_2143539_28	713586.KB900536_gene582	1.703e-142	465.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1WYRX@135613|Chromatiales	135613|Chromatiales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS2_k127_2143539_42	391615.ABSJ01000054_gene1462	2.841e-93	314.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,1S3EY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
CMS2_k127_2143539_33	519989.ECTPHS_05365	1.586e-112	370.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RNRI@1236|Gammaproteobacteria,1WYA5@135613|Chromatiales	135613|Chromatiales	I	Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS2_k127_2143539_39	519989.ECTPHS_05360	1.066e-101	352.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,1SI1R@1236|Gammaproteobacteria,1WWZB@135613|Chromatiales	135613|Chromatiales	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS2_k127_2143539_34	395493.BegalDRAFT_3110	9.094e-108	357.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,460UW@72273|Thiotrichales	72273|Thiotrichales	IQ	short-chain dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS2_k127_2143539_83	1230343.CANP01000031_gene2531	2.405e-07	55.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1JEQ8@118969|Legionellales	118969|Legionellales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS2_k127_2143539_63	1185876.BN8_01306	1.46e-50	184.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
CMS2_k127_2143539_47	519989.ECTPHS_05350	9.454e-82	277.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HhH-GPD	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
CMS2_k127_2143539_40	1120963.KB894497_gene2179	1.39e-98	329.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,2PZKA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_2143539_54	396588.Tgr7_2012	1.133e-76	263.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1WW3N@135613|Chromatiales	135613|Chromatiales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS2_k127_2143539_35	1049564.TevJSym_ah00730	4.781e-106	351.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1J4MQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS2_k127_2143539_11	472759.Nhal_3575	2.243e-214	670.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1WW43@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS2_k127_2143539_56	1026882.MAMP_01292	6.316e-69	241.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS2_k127_2143539_41	1396858.Q666_12620	1.468e-93	314.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,465FZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the SUA5 family	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
CMS2_k127_2143539_37	572477.Alvin_2196	1.281e-104	347.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1WXKB@135613|Chromatiales	135613|Chromatiales	S	pfam php	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
CMS2_k127_2143539_55	1049564.TevJSym_ah00790	9.403e-75	257.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1JAT3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	probably involved in intracellular septation	ispZ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
CMS2_k127_2143539_66	498211.CJA_1794	3.639e-46	168.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1FHIY@10|Cellvibrio	1236|Gammaproteobacteria	S	YCII-related domain	yciI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05527,ko:K09780	-	-	-	-	ko00000,ko03000	-	-	-	YCII
CMS2_k127_2143539_75	1122603.ATVI01000005_gene3417	3.438e-22	100.0	COG0271@1|root,COG0271@2|Bacteria,1QCDM@1224|Proteobacteria,1RTFD@1236|Gammaproteobacteria,1X7ES@135614|Xanthomonadales	135614|Xanthomonadales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
CMS2_k127_2143539_61	857087.Metme_1250	4.609e-57	208.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S3VR@1236|Gammaproteobacteria,1XDX1@135618|Methylococcales	135618|Methylococcales	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
CMS2_k127_2143539_0	1232410.KI421425_gene1552	0.0	2273.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS2_k127_2143539_2	1279017.AQYJ01000026_gene58	0.0	1500.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS2_k127_2161065_5	1177179.A11A3_14622	1.891e-10	61.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales	135619|Oceanospirillales	K	cold-shock protein	cspG	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_2161065_3	1283300.ATXB01000002_gene3039	5.185e-37	141.0	COG0724@1|root,COG0724@2|Bacteria,1NDEM@1224|Proteobacteria,1SFDX@1236|Gammaproteobacteria,1XFGC@135618|Methylococcales	135618|Methylococcales	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS2_k127_2161065_4	159087.Daro_1438	5.566e-25	108.0	COG3209@1|root,COG3209@2|Bacteria,1N7AI@1224|Proteobacteria,2VWKJ@28216|Betaproteobacteria,2KZKW@206389|Rhodocyclales	206389|Rhodocyclales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2161065_2	62928.azo1131	1.22e-37	148.0	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,2VIEE@28216|Betaproteobacteria,2KWQQ@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2161065_1	1380387.JADM01000002_gene1990	2.673e-79	269.0	COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,1S44B@1236|Gammaproteobacteria,1XP2W@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
CMS2_k127_2161065_0	1026882.MAMP_00158	2.638e-123	406.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS2_k127_2173424_9	1049564.TevJSym_af00130	1.431e-114	377.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1J5VE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	DnaJ-class molecular chaperone	cbpA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS2_k127_2173424_30	323261.Noc_1383	4.336e-22	100.0	COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,1WZDM@135613|Chromatiales	135613|Chromatiales	K	MerR HTH family regulatory protein	-	-	-	ko:K18997	-	-	-	-	ko00000,ko03036	-	-	-	MerR_2
CMS2_k127_2173424_15	1123368.AUIS01000019_gene1221	1.467e-76	263.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
CMS2_k127_2173424_3	1248232.BANQ01000013_gene957	2.004e-192	607.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XSWN@135623|Vibrionales	135623|Vibrionales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS2_k127_2173424_28	1122134.KB893650_gene236	1.587e-27	126.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria,1XKT3@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the frataxin family	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
CMS2_k127_2173424_14	1304275.C41B8_07925	1.076e-80	274.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS2_k127_2173424_2	1298593.TOL_0626	2.826e-197	630.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,1XRI7@135619|Oceanospirillales	135619|Oceanospirillales	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
CMS2_k127_2173424_0	396588.Tgr7_3185	3.407e-298	929.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS2_k127_2173424_27	519989.ECTPHS_04244	1.231e-27	113.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales	135613|Chromatiales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS2_k127_2173424_16	287.DR97_2707	9.228e-76	259.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1YCUK@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Guanylate_kin
CMS2_k127_2173424_12	323261.Noc_0956	8.971e-88	301.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1WX83@135613|Chromatiales	135613|Chromatiales	S	PFAM YicC-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS2_k127_2173424_11	1049564.TevJSym_as00340	4.53e-88	301.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,1RMDQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS2_k127_2173424_22	1049564.TevJSym_as00350	4.543e-62	225.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,1SZE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS2_k127_2173424_8	754476.Q7A_3058	3.24e-115	374.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,45ZZN@72273|Thiotrichales	72273|Thiotrichales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS2_k127_2173424_13	2340.JV46_12630	9.043e-88	293.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1J5SJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
CMS2_k127_2173424_5	105559.Nwat_0689	2.289e-153	494.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1WW8U@135613|Chromatiales	135613|Chromatiales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS2_k127_2173424_31	396588.Tgr7_2965	7.877e-10	64.0	COG4568@1|root,COG4568@2|Bacteria	2|Bacteria	K	rho-dependent transcription termination	rof	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K19000	-	-	-	-	ko00000,ko03021	-	-	-	ROF
CMS2_k127_2173424_24	765912.Thimo_0391	4.91e-41	158.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria,1WXHU@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2173424_26	713586.KB900536_gene2263	1.032e-38	150.0	COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,1ST0K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2173424_7	1123392.AQWL01000006_gene709	1.087e-131	429.0	COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,2VRTH@28216|Betaproteobacteria,1KSIM@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF302
CMS2_k127_2173424_17	1163617.SCD_n02414	5.611e-75	256.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
CMS2_k127_2173424_21	2340.JV46_11630	1.506e-66	228.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1J6BH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS2_k127_2173424_1	1049564.TevJSym_ai00870	2.045e-281	882.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1J4VK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS2_k127_2173424_23	713587.THITH_04285	5.378e-47	176.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5638	Chor_lyase
CMS2_k127_2173424_25	396588.Tgr7_0128	2.534e-40	161.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_2173424_19	105559.Nwat_0986	5.46e-68	239.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1WWVF@135613|Chromatiales	135613|Chromatiales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS2_k127_2173424_6	243233.MCA1125	1.944e-138	453.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XDXY@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
CMS2_k127_2173424_4	1042375.AFPL01000008_gene3284	7.621e-164	524.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4655Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830	Aminotran_1_2
CMS2_k127_2173424_18	1163617.SCD_n02664	1.785e-70	246.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria	28216|Betaproteobacteria	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS2_k127_2173424_10	519989.ECTPHS_06547	4.008e-88	299.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales	135613|Chromatiales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS2_k127_2173424_20	754477.Q7C_1313	3.92e-67	233.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,460T0@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS2_k127_2177878_9	1255043.TVNIR_3597	3.963e-42	156.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS2_k127_2177878_3	713586.KB900536_gene1763	1.812e-160	520.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
CMS2_k127_2177878_8	545264.KB898749_gene176	3.526e-75	255.0	28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,1SEW0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2177878_10	90814.KL370891_gene618	1.564e-38	152.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S9N2@1236|Gammaproteobacteria,462TV@72273|Thiotrichales	72273|Thiotrichales	C	Prokaryotic cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
CMS2_k127_2177878_6	1535422.ND16A_3444	5.413e-120	397.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,2Q8CP@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS2_k127_2177878_1	1163617.SCD_n01730	1.361e-265	835.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJI0@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA_2
CMS2_k127_2177878_4	1163617.SCD_n01729	1.36e-138	447.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
CMS2_k127_2177878_2	1049564.TevJSym_ag00680	8.111e-202	635.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,1RYIC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored,Pyr_redox_2
CMS2_k127_2177878_0	1163617.SCD_n01883	4.4e-323	1003.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
CMS2_k127_2177878_7	765911.Thivi_3112	1.511e-96	319.0	COG1150@1|root,COG1150@2|Bacteria,1R874@1224|Proteobacteria,1SHQ0@1236|Gammaproteobacteria,1WZZ0@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
CMS2_k127_2177878_5	765911.Thivi_3111	1.421e-138	447.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,1SBBX@1236|Gammaproteobacteria,1X060@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS2_k127_2178116_3	1268237.G114_12799	2.469e-27	120.0	COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,1Y437@135624|Aeromonadales	135624|Aeromonadales	S	nucleoid-associated protein	-	-	-	ko:K06899	-	-	-	-	ko00000,ko03036	-	-	-	NA37
CMS2_k127_2178116_1	1116472.MGMO_103c00140	6.838e-112	372.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,1T3H9@1236|Gammaproteobacteria,1XDWD@135618|Methylococcales	135618|Methylococcales	H	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS2_k127_2178116_2	1116472.MGMO_103c00130	3.052e-72	248.0	COG1309@1|root,COG1309@2|Bacteria,1N1X6@1224|Proteobacteria,1S9GI@1236|Gammaproteobacteria,1XDKS@135618|Methylococcales	135618|Methylococcales	K	PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_2178116_0	1565129.JSFF01000014_gene381	3.174e-123	402.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,2QA5Z@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	rbgA	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
CMS2_k127_2179347_0	396588.Tgr7_0696	6.409e-208	658.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1WWFZ@135613|Chromatiales	135613|Chromatiales	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
CMS2_k127_2179347_11	396588.Tgr7_3155	6.662e-20	98.0	COG2013@1|root,COG2013@2|Bacteria	2|Bacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
CMS2_k127_2179347_12	523791.Kkor_1048	1.411e-15	82.0	2E5B0@1|root,33033@2|Bacteria,1ND0X@1224|Proteobacteria,1SEBX@1236|Gammaproteobacteria,1XMD6@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2179347_3	483219.LILAB_23465	1.162e-112	379.0	COG2133@1|root,COG2133@2|Bacteria,1PER7@1224|Proteobacteria,4399G@68525|delta/epsilon subdivisions,2X4GV@28221|Deltaproteobacteria,2YYZS@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS2_k127_2179347_6	1232410.KI421413_gene485	9.876e-101	335.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria,43UFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS2_k127_2179347_5	323261.Noc_2719	1.782e-106	352.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,1S3T8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
CMS2_k127_2179347_2	1163617.SCD_n00017	1.391e-137	445.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,2VPIS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2179347_7	1122194.AUHU01000002_gene2545	4.653e-79	271.0	COG0421@1|root,COG0421@2|Bacteria,1QWZZ@1224|Proteobacteria,1T31M@1236|Gammaproteobacteria,467WD@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS2_k127_2179347_1	1123399.AQVE01000001_gene479	9.41e-198	628.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,1RQCS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CMS2_k127_2179347_4	519989.ECTPHS_04453	8.573e-112	381.0	COG1842@1|root,COG1842@2|Bacteria,1QW5I@1224|Proteobacteria	1224|Proteobacteria	KT	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS2_k127_2179347_13	472759.Nhal_2885	1.162e-13	72.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	natSF	-	2.3.1.102,2.3.1.128	ko:K03789,ko:K03790,ko:K03896	ko00310,ko01120,map00310,map01120	-	R03168	RC00004,RC00865	ko00000,ko00001,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
CMS2_k127_2179347_9	396588.Tgr7_2348	2.571e-40	153.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,1WZ6X@135613|Chromatiales	135613|Chromatiales	V	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
CMS2_k127_2179347_8	56780.SYN_02481	1.567e-74	259.0	COG0135@1|root,COG0135@2|Bacteria,1RA5Q@1224|Proteobacteria,42T4S@68525|delta/epsilon subdivisions,2WP9V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the TrpF family	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS2_k127_2179347_14	1219077.VAZ01S_085_00150	1.552e-08	59.0	2EEJ0@1|root,338D0@2|Bacteria,1N718@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2200582_18	396588.Tgr7_0798	1.286e-18	86.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WVXU@135613|Chromatiales	135613|Chromatiales	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS2_k127_2200582_12	1472716.KBK24_0126040	1.702e-51	185.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS2_k127_2200582_2	396588.Tgr7_0799	2.719e-198	626.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1WXAG@135613|Chromatiales	135613|Chromatiales	E	PFAM sodium alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS2_k127_2200582_13	395493.BegalDRAFT_1953	3.79e-51	188.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,4612T@72273|Thiotrichales	72273|Thiotrichales	S	Clan AA aspartic protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS2_k127_2200582_16	396588.Tgr7_0629	1.093e-34	135.0	COG0526@1|root,COG0526@2|Bacteria,1NC9Q@1224|Proteobacteria,1T0R2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CMS2_k127_2200582_8	713586.KB900536_gene1497	1.847e-73	255.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1WWUP@135613|Chromatiales	135613|Chromatiales	V	PFAM N-acetylmuramoyl-L-alanine amidase family 2	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
CMS2_k127_2200582_15	1049564.TevJSym_aa00750	2.763e-48	183.0	COG1270@1|root,COG1270@2|Bacteria	2|Bacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CMS2_k127_2200582_10	1452718.JBOY01000092_gene2691	3.588e-67	232.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,1S42M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobU	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_2074,iECSE_1348.ECSE_2277,iECW_1372.ECW_m2165,iETEC_1333.ETEC_2103,iEcE24377_1341.EcE24377A_2275,iEcSMS35_1347.EcSMS35_1131,iEcolC_1368.EcolC_1635,iLF82_1304.LF82_0337,iSDY_1059.SDY_2240,iWFL_1372.ECW_m2165	CobU
CMS2_k127_2200582_3	1316927.ATKI01000062_gene4197	8.965e-127	414.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,1RNPV@1236|Gammaproteobacteria,1YQ26@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	iSDY_1059.SDY_2242,iSF_1195.SF2059,iSFxv_1172.SFxv_2293,iS_1188.S2169	DBI_PRT
CMS2_k127_2200582_11	472759.Nhal_1052	2.245e-59	214.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1WXZH@135613|Chromatiales	135613|Chromatiales	G	PFAM Phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS2_k127_2200582_9	1395571.TMS3_0121295	4.218e-68	239.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,1S4TE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_2837,iECO103_1326.ECO103_2453,iECSP_1301.ECSP_2657,iECs_1301.ECs2787,iG2583_1286.G2583_2502,iUTI89_1310.UTI89_C2230,iZ_1308.Z3152,ic_1306.c2478	CobS
CMS2_k127_2200582_0	1123368.AUIS01000009_gene2455	0.0	1075.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,2NC0P@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Domain of unknown function (DUF3458_C) ARM repeats	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
CMS2_k127_2200582_6	1430440.MGMSRv2_1077	2.397e-96	330.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2TZQS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
CMS2_k127_2200582_14	1137799.GZ78_16560	5.928e-50	182.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,1XKHM@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the UPF0260 family	-	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS2_k127_2200582_19	765910.MARPU_03190	9.95e-15	78.0	2ESVH@1|root,33KDW@2|Bacteria,1NI9I@1224|Proteobacteria,1SJ2N@1236|Gammaproteobacteria,1X1P0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2200582_17	580332.Slit_2377	2.444e-24	106.0	COG3255@1|root,COG3255@2|Bacteria,1N93W@1224|Proteobacteria	1224|Proteobacteria	I	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
CMS2_k127_2200582_1	349521.HCH_00962	2.558e-222	700.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1XHE6@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CMS2_k127_2200582_5	243365.CV_1575	6.816e-103	342.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,2VIDF@28216|Betaproteobacteria,2KPJI@206351|Neisseriales	206351|Neisseriales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CMS2_k127_2200582_4	399739.Pmen_1754	1.016e-121	400.0	COG0079@1|root,COG0079@2|Bacteria,1MXDP@1224|Proteobacteria,1RR2V@1236|Gammaproteobacteria,1YDAX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Aminotransferase class I and II	cobC	-	2.6.1.9	ko:K00817,ko:K02225	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026,M00122	R00694,R00734,R03243,R06529,R07302	RC00006,RC00090,RC00096,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_2200582_7	85643.Tmz1t_3733	7.564e-95	319.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS2_k127_2270785_9	338963.Pcar_2897	6.118e-79	271.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2270785_12	290315.Clim_1223	8.411e-31	127.0	COG4446@1|root,COG4446@2|Bacteria,1FF8T@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS2_k127_2270785_3	1144275.COCOR_06378	5.944e-182	581.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
CMS2_k127_2270785_0	396588.Tgr7_1029	0.0	1124.0	COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria,1T23G@1236|Gammaproteobacteria,1X2J6@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_2270785_4	1049564.TevJSym_au00430	3.608e-166	538.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1J524@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS2_k127_2270785_8	870187.Thini_3121	4.488e-82	282.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,460KX@72273|Thiotrichales	72273|Thiotrichales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CMS2_k127_2270785_11	472759.Nhal_3458	2.564e-65	232.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1WXQH@135613|Chromatiales	135613|Chromatiales	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS2_k127_2270785_10	1397527.Q670_05200	2.09e-71	243.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales	135619|Oceanospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS2_k127_2270785_7	1122134.KB893650_gene1012	3.015e-92	308.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XHX2@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS2_k127_2270785_2	870187.Thini_2806	1.159e-195	621.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,46042@72273|Thiotrichales	72273|Thiotrichales	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS2_k127_2270785_1	1026882.MAMP_01338	0.0	1123.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,45ZVX@72273|Thiotrichales	72273|Thiotrichales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CMS2_k127_2270785_5	1163617.SCD_n01943	3.888e-123	401.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria	28216|Betaproteobacteria	BQ	histone deacetylase	hda	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS2_k127_2270785_6	187272.Mlg_1653	3.532e-99	325.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria,1WW7Y@135613|Chromatiales	135613|Chromatiales	C	reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS2_k127_2316311_8	1073999.BN137_3415	7.268e-11	62.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	iSDY_1059.SDY_4251	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_2316311_0	765910.MARPU_10605	0.0	1342.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWJE@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS2_k127_2316311_2	1323663.AROI01000010_gene3314	1.42e-75	266.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,1RXZ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_2316311_5	765910.MARPU_10615	5.302e-45	170.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1S8XT@1236|Gammaproteobacteria,1WY3W@135613|Chromatiales	135613|Chromatiales	K	AefR-like transcriptional repressor, C-terminal region	-	-	-	ko:K18301	-	M00642	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	TetR_C_7,TetR_N
CMS2_k127_2316311_3	395495.Lcho_4380	1.513e-70	247.0	COG4305@1|root,COG4305@2|Bacteria,1MYW4@1224|Proteobacteria,2WFKE@28216|Betaproteobacteria,1KNUF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lytic transglycolase	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1
CMS2_k127_2316311_1	292415.Tbd_2287	8.825e-116	378.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VQQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
CMS2_k127_2316311_6	1535422.ND16A_2163	3.214e-21	102.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1THKF@1236|Gammaproteobacteria,2Q74Z@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS2_k127_2316311_4	283942.IL0625	1.558e-56	217.0	COG2159@1|root,COG2159@2|Bacteria,1NAC7@1224|Proteobacteria	1224|Proteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS2_k127_2316311_7	713586.KB900536_gene2312	2.557e-15	76.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales	1236|Gammaproteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_233587_1	392500.Swoo_4272	7.806e-112	370.0	COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
CMS2_k127_233587_0	314345.SPV1_09583	3.72e-216	681.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria	1224|Proteobacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS2_k127_2349082_0	697282.Mettu_3480	1.278e-219	690.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales	135618|Methylococcales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS2_k127_2349082_3	1049564.TevJSym_bd00130	5.464e-121	396.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CF	catalyzes the conversion of	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS2_k127_2349082_2	265072.Mfla_1648	3.14e-161	520.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,2KM89@206350|Nitrosomonadales	206350|Nitrosomonadales	EH	Anthranilate synthase component I	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS2_k127_2349082_4	391615.ABSJ01000059_gene2177	6.391e-58	202.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1J6ER@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	VL23_01195	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS2_k127_2349082_5	1328313.DS2_16639	1.722e-43	161.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,46792@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS2_k127_2349082_1	472759.Nhal_3203	4.181e-174	557.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1WW51@135613|Chromatiales	135613|Chromatiales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS2_k127_2441275_11	187272.Mlg_2285	9.242e-38	143.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1WYVU@135613|Chromatiales	135613|Chromatiales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS2_k127_2441275_0	395493.BegalDRAFT_2469	0.0	1183.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS2_k127_2441275_2	187272.Mlg_2287	5.159e-221	691.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1WX82@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS2_k127_2441275_8	2340.JV46_28080	3.285e-105	344.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1J4TT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS2_k127_2441275_7	1122197.ATWI01000009_gene1941	6.7e-121	401.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,46543@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS2_k127_2441275_19	1127673.GLIP_2679	1.035e-05	48.0	2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2441275_5	1255043.TVNIR_2766	1.436e-128	420.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1WWQ4@135613|Chromatiales	135613|Chromatiales	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS2_k127_2441275_14	1116375.VEJY3_20306	1.146e-24	109.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1XXAS@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
CMS2_k127_2441275_13	323261.Noc_0327	5.974e-35	139.0	COG0526@1|root,COG0526@2|Bacteria,1MZ9B@1224|Proteobacteria,1SBA1@1236|Gammaproteobacteria,1X1F2@135613|Chromatiales	135613|Chromatiales	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS2_k127_2441275_6	697282.Mettu_2372	5.687e-127	419.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,1S27X@1236|Gammaproteobacteria,1XF6U@135618|Methylococcales	135618|Methylococcales	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2441275_1	1255043.TVNIR_2748	1.332e-269	846.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,1T241@1236|Gammaproteobacteria,1X094@135613|Chromatiales	135613|Chromatiales	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS2_k127_2441275_15	2340.JV46_08370	2.667e-20	100.0	COG0810@1|root,COG5297@1|root,COG0810@2|Bacteria,COG5297@2|Bacteria,1PDUM@1224|Proteobacteria,1SWIX@1236|Gammaproteobacteria,1JB5U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS2_k127_2441275_18	338963.Pcar_2390	1.445e-16	87.0	COG0848@1|root,COG0848@2|Bacteria,1PQM0@1224|Proteobacteria,42VT0@68525|delta/epsilon subdivisions,2WRBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS2_k127_2441275_9	2340.JV46_08350	6.791e-62	222.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1S2ZN@1236|Gammaproteobacteria,1J733@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_2441275_10	1121035.AUCH01000023_gene3425	1.998e-40	158.0	COG4232@1|root,COG4232@2|Bacteria,1N8UG@1224|Proteobacteria,2VSTK@28216|Betaproteobacteria,2KZFF@206389|Rhodocyclales	206389|Rhodocyclales	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS2_k127_2441275_4	207954.MED92_04402	2.452e-138	448.0	COG0348@1|root,COG0348@2|Bacteria,1QTQB@1224|Proteobacteria,1RXUW@1236|Gammaproteobacteria,1XN2H@135619|Oceanospirillales	135619|Oceanospirillales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_5
CMS2_k127_2441275_12	207954.MED92_04407	5.542e-36	148.0	2ANXW@1|root,31DYS@2|Bacteria,1MYQS@1224|Proteobacteria,1SG6T@1236|Gammaproteobacteria,1XP6U@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2441275_3	709032.Sulku_2469	1.485e-149	489.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,42PHJ@68525|delta/epsilon subdivisions,2YNKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS2_k127_2489192_27	1279017.AQYJ01000029_gene3401	1.548e-11	65.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,46C71@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2489192_10	472759.Nhal_0795	4.222e-140	467.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1WWAA@135613|Chromatiales	135613|Chromatiales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
CMS2_k127_2489192_4	1163617.SCD_n02608	1.12e-189	602.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2VIZB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
CMS2_k127_2489192_1	1232410.KI421426_gene1440	5.905e-272	858.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,43UHA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bifunctional transglycosylase second domain	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
CMS2_k127_2489192_25	1232410.KI421426_gene1441	3.538e-31	128.0	COG3063@1|root,COG3063@2|Bacteria,1QZ5S@1224|Proteobacteria,42XK8@68525|delta/epsilon subdivisions,2WSKB@28221|Deltaproteobacteria,43V3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2489192_23	1026882.MAMP_00095	1.607e-40	158.0	COG2433@1|root,COG2433@2|Bacteria,1QWB7@1224|Proteobacteria,1T3FV@1236|Gammaproteobacteria,463WV@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial SH3 domain homologues	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
CMS2_k127_2489192_5	1219072.VHA01S_008_01060	7.29e-177	562.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC2	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS2_k127_2489192_12	713586.KB900536_gene465	6.2e-108	357.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales	135613|Chromatiales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS2_k127_2489192_22	1049564.TevJSym_ab01490	1.885e-45	174.0	COG3850@1|root,COG3850@2|Bacteria,1N23T@1224|Proteobacteria,1S55G@1236|Gammaproteobacteria,1JB54@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	PilJ
CMS2_k127_2489192_2	1144319.PMI16_02732	3.505e-203	649.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2VHFM@28216|Betaproteobacteria,473YT@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS2_k127_2489192_7	555778.Hneap_0396	2.516e-161	514.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1X292@135613|Chromatiales	135613|Chromatiales	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
CMS2_k127_2489192_8	1167006.UWK_02555	8.331e-160	510.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,42P23@68525|delta/epsilon subdivisions,2WK75@28221|Deltaproteobacteria,2MIZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
CMS2_k127_2489192_3	1095769.CAHF01000010_gene1145	6.83e-201	639.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,4724D@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
CMS2_k127_2489192_28	1158318.ATXC01000001_gene185	3.089e-11	70.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	bta	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin,TraF
CMS2_k127_2489192_17	583355.Caka_2172	1.27e-72	254.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
CMS2_k127_2489192_14	349521.HCH_00790	2.359e-99	332.0	COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphoesterase DHHA1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
CMS2_k127_2489192_21	1123368.AUIS01000007_gene2818	7.917e-46	174.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
CMS2_k127_2489192_20	1123401.JHYQ01000048_gene2007	2.667e-52	189.0	2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,1S4WN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2489192_13	1288494.EBAPG3_30110	3.662e-102	346.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,372J0@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
CMS2_k127_2489192_16	1198232.CYCME_1229	2.093e-73	255.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,1RQ9U@1236|Gammaproteobacteria,460HM@72273|Thiotrichales	72273|Thiotrichales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_2489192_26	1123393.KB891328_gene656	6.552e-20	94.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
CMS2_k127_2489192_18	572477.Alvin_2284	3.263e-66	229.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1WXYW@135613|Chromatiales	135613|Chromatiales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS2_k127_2489192_11	1049564.TevJSym_ab00610	2.112e-111	364.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,1J6UP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS2_k127_2489192_6	396588.Tgr7_2043	1.567e-162	520.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1WWTQ@135613|Chromatiales	135613|Chromatiales	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS2_k127_2489192_15	1049564.TevJSym_an00130	1.021e-75	261.0	COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1J5RJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway	cysZ	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600	-	ko:K06203	-	-	-	-	ko00000	-	-	iJR904.b2413,iYL1228.KPN_02760	EI24
CMS2_k127_2489192_9	396588.Tgr7_2028	3.427e-149	483.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1WW9A@135613|Chromatiales	135613|Chromatiales	G	PFAM carbohydrate kinase	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS2_k127_2489192_24	713586.KB900536_gene1484	3.843e-33	136.0	2EN7Y@1|root,33FVR@2|Bacteria,1NHR8@1224|Proteobacteria,1SH6M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2489192_19	754477.Q7C_43	2.263e-65	227.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,461HI@72273|Thiotrichales	72273|Thiotrichales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
CMS2_k127_2489192_0	396588.Tgr7_2026	0.0	1245.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1WW7V@135613|Chromatiales	135613|Chromatiales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS2_k127_2489192_29	1219375.CM002139_gene3158	1.019e-08	63.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1X3YH@135614|Xanthomonadales	135614|Xanthomonadales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
CMS2_k127_2612173_61	396588.Tgr7_2468	2.386e-27	118.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS2_k127_2612173_62	396588.Tgr7_3177	5.111e-21	104.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria	1224|Proteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
CMS2_k127_2612173_43	713587.THITH_09405	1.822e-56	198.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1WYW2@135613|Chromatiales	135613|Chromatiales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS2_k127_2612173_5	713586.KB900536_gene37	6.976e-248	797.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria	1224|Proteobacteria	L	double-strand break repair protein AddB	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
CMS2_k127_2612173_1	713586.KB900536_gene929	9.746e-305	970.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales	135613|Chromatiales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS2_k127_2612173_34	765910.MARPU_13475	1.719e-80	277.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1WXMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS2_k127_2612173_38	713586.KB900536_gene931	2.344e-68	240.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1WXSE@135613|Chromatiales	135613|Chromatiales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
CMS2_k127_2612173_41	105559.Nwat_2086	1.592e-57	204.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1WXZ5@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
CMS2_k127_2612173_20	1117958.PE143B_0115515	9.941e-124	404.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	recombinase XerD	xerD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS2_k127_2612173_53	472759.Nhal_0929	3.323e-41	156.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1WYKN@135613|Chromatiales	135613|Chromatiales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS2_k127_2612173_42	1122134.KB893651_gene2158	1.328e-56	199.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1XJT2@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS2_k127_2612173_26	187272.Mlg_0886	3.414e-109	357.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1WWK4@135613|Chromatiales	135613|Chromatiales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS2_k127_2612173_40	323261.Noc_2259	1.593e-60	214.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1WY0M@135613|Chromatiales	135613|Chromatiales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS2_k127_2612173_56	351348.Maqu_2280	3.598e-35	136.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,467U2@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS2_k127_2612173_7	1286106.MPL1_11663	5.677e-214	673.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS2_k127_2612173_33	396588.Tgr7_0844	3.304e-81	277.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,1S453@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS2_k127_2612173_35	472759.Nhal_0923	7.6e-75	259.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales	135613|Chromatiales	S	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS2_k127_2612173_11	396588.Tgr7_0842	1.024e-164	527.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1WWQM@135613|Chromatiales	135613|Chromatiales	P	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS2_k127_2612173_60	522306.CAP2UW1_0660	1.858e-30	128.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS2_k127_2612173_9	521719.ATXQ01000001_gene471	6.335e-194	614.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1YDC4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS2_k127_2612173_52	1265505.ATUG01000001_gene4622	1.003e-42	160.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2MKE0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
CMS2_k127_2612173_24	314278.NB231_16028	1.204e-119	394.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1WWIB@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS2_k127_2612173_8	1026882.MAMP_03131	8.331e-212	666.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales	72273|Thiotrichales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS2_k127_2612173_46	1219065.VPR01S_31_00060	1.891e-55	197.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1XU9I@135623|Vibrionales	135623|Vibrionales	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS2_k127_2612173_51	765911.Thivi_1183	5.432e-46	178.0	2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,1WXMV@135613|Chromatiales	135613|Chromatiales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
CMS2_k127_2612173_55	1046724.KB889908_gene946	1.029e-36	139.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,467T8@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS2_k127_2612173_63	314278.NB231_16003	9.071e-18	86.0	COG2965@1|root,COG2965@2|Bacteria,1RHIE@1224|Proteobacteria,1S6H5@1236|Gammaproteobacteria,1X20V@135613|Chromatiales	135613|Chromatiales	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
CMS2_k127_2612173_48	395493.BegalDRAFT_3157	4.005e-51	184.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,460SS@72273|Thiotrichales	72273|Thiotrichales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS2_k127_2612173_32	1209072.ALBT01000023_gene3987	1.231e-82	282.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1FFXM@10|Cellvibrio	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS2_k127_2612173_3	323261.Noc_2897	5.633e-299	934.0	COG0557@1|root,COG2345@1|root,COG0557@2|Bacteria,COG2345@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
CMS2_k127_2612173_6	713587.THITH_03520	1.128e-217	681.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1WW9J@135613|Chromatiales	135613|Chromatiales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS2_k127_2612173_18	1049564.TevJSym_bl00150	2.418e-145	470.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1J4S0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CMS2_k127_2612173_64	314278.NB231_15488	1.017e-10	64.0	COG3242@1|root,COG3242@2|Bacteria,1PU4H@1224|Proteobacteria,1RWCT@1236|Gammaproteobacteria,1WZPF@135613|Chromatiales	135613|Chromatiales	S	protein conserved in bacteria	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
CMS2_k127_2612173_27	472759.Nhal_3725	1.884e-103	344.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1WW0U@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could regulate a protease	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS2_k127_2612173_21	1026882.MAMP_01811	5.345e-123	407.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS2_k127_2612173_13	349521.HCH_05382	3.241e-162	521.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XHR4@135619|Oceanospirillales	135619|Oceanospirillales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS2_k127_2612173_57	765913.ThidrDRAFT_3563	4.233e-35	136.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1WYTY@135613|Chromatiales	135613|Chromatiales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
CMS2_k127_2612173_23	1121878.AUGL01000019_gene1502	1.791e-121	398.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS2_k127_2612173_16	1122201.AUAZ01000021_gene3191	5.347e-157	514.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,464TH@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS2_k127_2612173_19	1049564.TevJSym_bl00230	8.131e-139	454.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1J4PG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225	AMIN,Amidase_3,LysM
CMS2_k127_2612173_50	593105.S7A_01900	5.466e-50	182.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,3W0N6@53335|Pantoea	1236|Gammaproteobacteria	S	possibly involved in cell wall synthesis	yjeE	GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS2_k127_2612173_14	472759.Nhal_3428	1.786e-161	524.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales	135613|Chromatiales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS2_k127_2612173_15	713586.KB900536_gene2952	8.555e-159	508.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1WWZ4@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS2_k127_2612173_30	1026882.MAMP_01056	2.978e-90	306.0	COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,460KJ@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB,Rieske
CMS2_k127_2612173_37	187272.Mlg_1355	1.607e-69	242.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1WYQS@135613|Chromatiales	135613|Chromatiales	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS2_k127_2612173_45	1565129.JSFF01000025_gene1307	1.68e-55	204.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,2Q8MQ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2604,iEcHS_1320.EcHS_A4080,iEcolC_1368.EcolC_4158,iLF82_1304.LF82_1370,iNRG857_1313.NRG857_19230,iSBO_1134.SBO_3869,iSbBS512_1146.SbBS512_E4329,iUMNK88_1353.UMNK88_4686,ic_1306.c4801	NTP_transf_3
CMS2_k127_2612173_44	396588.Tgr7_2131	3.306e-56	201.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria,1WY0J@135613|Chromatiales	135613|Chromatiales	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
CMS2_k127_2612173_17	472759.Nhal_2468	1.643e-148	482.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1WVYA@135613|Chromatiales	135613|Chromatiales	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS2_k127_2612173_0	1163617.SCD_n01479	0.0	1167.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,2W1SU@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS2_k127_2612173_59	1122134.KB893650_gene1311	1.476e-32	134.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1XS8J@135619|Oceanospirillales	135619|Oceanospirillales	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
CMS2_k127_2612173_22	187272.Mlg_0737	1.088e-122	402.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS2_k127_2612173_25	713587.THITH_01350	7.923e-115	373.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS2_k127_2612173_28	1163617.SCD_n02932	1.022e-100	340.0	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,2W16H@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2612173_12	1049564.TevJSym_aw00330	2.908e-164	527.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
CMS2_k127_2612173_10	572477.Alvin_2108	1.578e-186	586.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,1WW3S@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS2_k127_2612173_47	1249627.D779_1932	2.33e-52	190.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,1S56W@1236|Gammaproteobacteria,1WYDD@135613|Chromatiales	135613|Chromatiales	F	pfam nudix	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS2_k127_2612173_49	1123368.AUIS01000009_gene2457	1.942e-50	182.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S8VM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA3	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS2_k127_2612173_54	545264.KB898752_gene2337	1.854e-37	145.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the HSP15 family	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CMS2_k127_2612173_31	96561.Dole_0111	2.741e-89	302.0	COG0189@1|root,COG0189@2|Bacteria,1MWQA@1224|Proteobacteria,43B1R@68525|delta/epsilon subdivisions,2X6FW@28221|Deltaproteobacteria,2MJ6I@213118|Desulfobacterales	28221|Deltaproteobacteria	HJ	RimK-like ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
CMS2_k127_2612173_36	1163617.SCD_n00294	3.779e-70	240.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2VRA3@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_2612173_58	1123392.AQWL01000004_gene2785	5.865e-33	135.0	COG3637@1|root,COG3637@2|Bacteria,1PWS4@1224|Proteobacteria,2WAG8@28216|Betaproteobacteria,1KTGR@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
CMS2_k127_2612173_39	338963.Pcar_1391	5.647e-68	234.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42RIQ@68525|delta/epsilon subdivisions,2WNC7@28221|Deltaproteobacteria,43SKU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS2_k127_2612173_2	1163617.SCD_n00964	1.85e-300	932.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS2_k127_2612173_4	1049564.TevJSym_ay00240	1.055e-251	786.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,1RPDV@1236|Gammaproteobacteria,1J5GA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS2_k127_2639232_3	930166.CD58_00275	6.81e-56	201.0	COG3218@1|root,COG3218@2|Bacteria,1RED4@1224|Proteobacteria,1SYNV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	transport system, auxiliary component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
CMS2_k127_2639232_2	930166.CD58_00280	1.559e-70	247.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,1S5E8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS2_k127_2639232_1	1397528.Q671_04710	6.897e-115	376.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RQVA@1236|Gammaproteobacteria,1XKBM@135619|Oceanospirillales	135619|Oceanospirillales	Q	ABC transporter ATP-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS2_k127_2639232_0	644801.Psest_4255	4.165e-135	440.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria,1Z02K@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	mlaE_1	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
CMS2_k127_2639232_4	525897.Dbac_1053	3.308e-47	173.0	COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1MVAW@1224|Proteobacteria,42MYC@68525|delta/epsilon subdivisions,2WJXA@28221|Deltaproteobacteria,2M8XJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
CMS2_k127_2675977_0	1122929.KB908229_gene3403	0.0	1511.0	2DB7G@1|root,2Z7M5@2|Bacteria,1R539@1224|Proteobacteria,2TUW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2675977_1	1122929.KB908229_gene3404	2.643e-185	591.0	28JCI@1|root,2Z976@2|Bacteria,1RDT1@1224|Proteobacteria,2UAU9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2675977_2	1122929.KB908229_gene3405	1.162e-65	230.0	28JCI@1|root,3221E@2|Bacteria,1NA2C@1224|Proteobacteria,2UU60@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2698089_5	1049564.TevJSym_al00690	5.422e-136	448.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1J7D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	narX	GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	2.7.13.3	ko:K07673,ko:K07674	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
CMS2_k127_2698089_3	1123392.AQWL01000003_gene164	1.734e-190	604.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,1KRHX@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
CMS2_k127_2698089_1	1049564.TevJSym_ag00810	0.0	1002.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,1J96M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	nitrate nitrite transporter	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
CMS2_k127_2698089_0	1049564.TevJSym_ag00800	0.0	2217.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
CMS2_k127_2698089_2	1049564.TevJSym_ag00790	7.195e-284	878.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase beta subunit	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
CMS2_k127_2698089_10	1049564.TevJSym_ag00780	7.755e-58	208.0	COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,1SQFJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitrate reductase delta subunit	-	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
CMS2_k127_2698089_8	1049564.TevJSym_ag00770	1.853e-99	329.0	COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,1RPTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase, gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
CMS2_k127_2698089_11	1049564.TevJSym_ag00760	3.272e-47	172.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS2_k127_2698089_9	1268237.G114_11190	1.303e-88	297.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1Y3SW@135624|Aeromonadales	135624|Aeromonadales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS2_k127_2698089_6	323261.Noc_1755	1.321e-135	439.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1SYTB@1236|Gammaproteobacteria,1WWFT@135613|Chromatiales	135613|Chromatiales	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS2_k127_2698089_4	269799.Gmet_2351	2.644e-167	532.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	gnnB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2351	DegT_DnrJ_EryC1
CMS2_k127_2698089_7	472759.Nhal_1230	1.44e-118	389.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales	135613|Chromatiales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS2_k127_2708046_3	1177181.T9A_01682	5.151e-122	395.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1XH98@135619|Oceanospirillales	135619|Oceanospirillales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS2_k127_2708046_10	323261.Noc_1694	3.035e-23	110.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1WZA1@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
CMS2_k127_2708046_1	472759.Nhal_1449	1.258e-283	885.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1WX4B@135613|Chromatiales	135613|Chromatiales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS2_k127_2708046_6	1232410.KI421425_gene1551	8.446e-53	191.0	2B4XH@1|root,32REP@2|Bacteria,1PXEZ@1224|Proteobacteria,4305C@68525|delta/epsilon subdivisions,2WVH5@28221|Deltaproteobacteria,43UUP@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2708046_2	1232410.KI421425_gene1550	3.294e-230	730.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,42Z0Q@68525|delta/epsilon subdivisions,2WU0G@28221|Deltaproteobacteria,43T6R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2708046_0	1232410.KI421425_gene1549	0.0	1142.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,43CT2@68525|delta/epsilon subdivisions,2X80K@28221|Deltaproteobacteria,43TUA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS2_k127_2708046_7	1232410.KI421425_gene1548	3.498e-49	182.0	COG0457@1|root,COG0457@2|Bacteria,1N1J2@1224|Proteobacteria,42ZHG@68525|delta/epsilon subdivisions,2WV2W@28221|Deltaproteobacteria,43UR6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2708046_11	443144.GM21_0441	3.696e-19	91.0	2EQ5T@1|root,32ZV0@2|Bacteria,1NFTI@1224|Proteobacteria,433CK@68525|delta/epsilon subdivisions,2WXC2@28221|Deltaproteobacteria,43VWA@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2708046_5	1232410.KI421425_gene1546	2.253e-81	275.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,43TGA@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_2708046_8	1232410.KI421425_gene1545	1.829e-43	164.0	COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,43UYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS2_k127_2708046_9	1177154.Y5S_01708	1.342e-42	161.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS2_k127_2708046_4	1279017.AQYJ01000026_gene59	1.856e-104	355.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS2_k127_2725664_17	697282.Mettu_1618	7.76e-91	300.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1XDJI@135618|Methylococcales	135618|Methylococcales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_2725664_39	398578.Daci_1409	2.177e-16	80.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2VRA9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
CMS2_k127_2725664_35	396588.Tgr7_2897	3.654e-27	122.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS2_k127_2725664_20	1049564.TevJSym_ax00450	2.008e-84	291.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS2_k127_2725664_0	1122201.AUAZ01000009_gene2878	0.0	1181.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS2_k127_2725664_14	1278307.KB907006_gene215	5.899e-100	333.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,2QHJ0@267894|Psychromonadaceae	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS2_k127_2725664_33	2340.JV46_18630	3.483e-30	123.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1JBXM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS2_k127_2725664_38	1397527.Q670_01710	8.89e-19	87.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1XM7C@135619|Oceanospirillales	135619|Oceanospirillales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS2_k127_2725664_26	323261.Noc_3057	1.824e-46	170.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
CMS2_k127_2725664_27	572477.Alvin_2793	1.963e-46	169.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1WYHH@135613|Chromatiales	135613|Chromatiales	E	phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
CMS2_k127_2725664_23	1122236.KB905143_gene14	3.97e-59	206.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,2KMS4@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
CMS2_k127_2725664_8	491952.Mar181_0422	9.228e-142	452.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1XIEI@135619|Oceanospirillales	135619|Oceanospirillales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_2725664_10	396588.Tgr7_0215	8.355e-129	414.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1WXHX@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS2_k127_2725664_19	1042375.AFPL01000043_gene1334	7.161e-86	289.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,465J2@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS2_k127_2725664_12	396588.Tgr7_0213	2.822e-103	338.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1WVVY@135613|Chromatiales	135613|Chromatiales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS2_k127_2725664_16	765912.Thimo_1319	5.311e-94	315.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_2725664_3	768671.ThimaDRAFT_2264	6.147e-269	832.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1WXK9@135613|Chromatiales	135613|Chromatiales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CMS2_k127_2725664_11	1049564.TevJSym_au00640	1.86e-106	349.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CMS2_k127_2725664_37	1249627.D779_2443	2.035e-19	90.0	2E5UC@1|root,330IN@2|Bacteria,1NAMZ@1224|Proteobacteria,1SCK7@1236|Gammaproteobacteria,1WZB2@135613|Chromatiales	135613|Chromatiales	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
CMS2_k127_2725664_13	1049564.TevJSym_au00660	3.321e-103	342.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1J545@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS2_k127_2725664_6	765912.Thimo_1342	4.788e-191	608.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM cytochrome c oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS2_k127_2725664_32	1249627.D779_2446	3.49e-33	136.0	COG5456@1|root,COG5456@2|Bacteria,1RFTY@1224|Proteobacteria,1S4W0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
CMS2_k127_2725664_1	580332.Slit_0418	0.0	1074.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,44VHX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CMS2_k127_2725664_40	395494.Galf_0268	3.262e-16	81.0	COG3197@1|root,COG3197@2|Bacteria,1PWZD@1224|Proteobacteria,2WCHB@28216|Betaproteobacteria,44W3I@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS2_k127_2725664_24	1485544.JQKP01000002_gene1339	3.937e-53	194.0	2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,2VQZS@28216|Betaproteobacteria,44VTJ@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2725664_31	765911.Thivi_4158	3.493e-34	138.0	28P01@1|root,2ZBWR@2|Bacteria,1RB5K@1224|Proteobacteria,1S2PB@1236|Gammaproteobacteria,1WXYS@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2725664_28	2340.JV46_05360	6.124e-46	173.0	COG2010@1|root,COG2010@2|Bacteria,1PDUJ@1224|Proteobacteria,1SUEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
CMS2_k127_2725664_36	1379270.AUXF01000001_gene2219	6.242e-22	103.0	COG2771@1|root,COG2771@2|Bacteria	2|Bacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS2_k127_2725664_22	765910.MARPU_00325	1.775e-59	214.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1WYB4@135613|Chromatiales	135613|Chromatiales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS2_k127_2725664_7	1215092.PA6_002_00140	7.102e-156	496.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1YE85@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS2_k127_2725664_29	1026882.MAMP_03137	1.793e-43	167.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,4613A@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
CMS2_k127_2725664_30	998674.ATTE01000001_gene3458	8.588e-35	139.0	COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1SDBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
CMS2_k127_2725664_34	627192.SLG_01400	4.711e-29	117.0	COG1396@1|root,COG1396@2|Bacteria,1MZQK@1224|Proteobacteria,2UCAK@28211|Alphaproteobacteria,2K7KZ@204457|Sphingomonadales	204457|Sphingomonadales	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_2725664_2	1249627.D779_3681	2.733e-286	892.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,1RM9Q@1236|Gammaproteobacteria,1WW1W@135613|Chromatiales	135613|Chromatiales	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
CMS2_k127_2725664_9	765912.Thimo_3204	1.482e-136	449.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,1RPCY@1236|Gammaproteobacteria,1WWK9@135613|Chromatiales	135613|Chromatiales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
CMS2_k127_2725664_18	765910.MARPU_16420	9.97e-90	301.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,1RRYF@1236|Gammaproteobacteria,1WXDQ@135613|Chromatiales	135613|Chromatiales	C	hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS2_k127_2725664_4	765911.Thivi_2910	4.219e-252	784.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,1RPB3@1236|Gammaproteobacteria,1WWDM@135613|Chromatiales	135613|Chromatiales	CP	PFAM NADH Ubiquinone plastoquinone	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
CMS2_k127_2725664_5	713586.KB900536_gene1510	2.376e-203	656.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,1RSJ4@1236|Gammaproteobacteria,1WWJR@135613|Chromatiales	135613|Chromatiales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
CMS2_k127_2725664_21	1249627.D779_1012	1.151e-82	278.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,1RNUG@1236|Gammaproteobacteria,1WY4E@135613|Chromatiales	135613|Chromatiales	C	PFAM NADH Ubiquinone	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
CMS2_k127_2725664_15	29495.EA26_01370	7.035e-100	328.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1XTQJ@135623|Vibrionales	135623|Vibrionales	T	membrane GTPase involved in stress response	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_277134_1	1121405.dsmv_1276	9.765e-50	181.0	2BEKE@1|root,328BU@2|Bacteria,1RM2J@1224|Proteobacteria,42TNQ@68525|delta/epsilon subdivisions,2WQG6@28221|Deltaproteobacteria,2MNP3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
CMS2_k127_277134_0	1121405.dsmv_1275	1.366e-142	467.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WM12@28221|Deltaproteobacteria,2MPXA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
CMS2_k127_277134_2	215803.DB30_0203	9.07e-41	159.0	2EJXK@1|root,33DN8@2|Bacteria,1NUR9@1224|Proteobacteria,439D3@68525|delta/epsilon subdivisions,2X4MR@28221|Deltaproteobacteria,2YZ9I@29|Myxococcales	28221|Deltaproteobacteria	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS2_k127_277134_3	393595.ABO_2143	9.366e-21	96.0	2E9ZQ@1|root,33454@2|Bacteria,1NEMD@1224|Proteobacteria,1SU0F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_277134_4	1033802.SSPSH_002283	1.888e-13	71.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC	btuF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015889,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0031419,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0097159,GO:1901363	-	ko:K02016,ko:K06858	ko02010,map02010	M00240,M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13,3.A.1.14	-	iECH74115_1262.ECH74115_0168,iECSP_1301.ECSP_0159,iECs_1301.ECs0162,iZ_1308.Z0169	Peripla_BP_2
CMS2_k127_278127_3	1049564.TevJSym_ar00210	1.425e-142	463.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1J4X2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Nucleoside H+ symporter	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
CMS2_k127_278127_2	1288826.MSNKSG1_06563	1.061e-197	619.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,46517@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518	Chorismate_synt
CMS2_k127_278127_0	395493.BegalDRAFT_2990	1.374e-215	677.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,45ZXR@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS2_k127_278127_7	1049564.TevJSym_av00440	1.162e-18	90.0	2E5B5@1|root,33039@2|Bacteria,1NDK8@1224|Proteobacteria,1SFKE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_278127_4	472759.Nhal_0269	2.89e-116	383.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
CMS2_k127_278127_5	1485545.JQLW01000005_gene882	9.432e-89	295.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria	1224|Proteobacteria	H	May be involved in the biosynthesis of molybdopterin	mog	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1969,iECABU_c1320.ECABU_c00100,iECED1_1282.ECED1_0009,iECNA114_1301.ECNA114_4653,iECP_1309.ECP_0010,iECS88_1305.ECS88_0010,iECSF_1327.ECSF_0009,iECUMN_1333.ECUMN_0010,iEcSMS35_1347.EcSMS35_0008,iLF82_1304.LF82_1379,iNRG857_1313.NRG857_00050,iUMN146_1321.UM146_22820	MoCF_biosynth
CMS2_k127_278127_1	768671.ThimaDRAFT_4172	3.579e-202	633.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS2_k127_278127_6	292415.Tbd_1586	3.197e-31	123.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
CMS2_k127_2946076_1	713586.KB900536_gene996	2.199e-292	906.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1WWDG@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS2_k127_2946076_16	1026882.MAMP_02279	2.061e-76	258.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,460NY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
CMS2_k127_2946076_5	1232683.ADIMK_2925	2.677e-191	600.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,464ET@72275|Alteromonadaceae	1236|Gammaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103	IlvC,IlvN
CMS2_k127_2946076_12	472759.Nhal_0658	2.129e-99	334.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1WWDZ@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS2_k127_2946076_2	396588.Tgr7_2153	6.702e-269	837.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS2_k127_2946076_18	1049564.TevJSym_am00800	4.877e-51	192.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS2_k127_2946076_20	1236959.BAMT01000005_gene90	4.153e-25	111.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,2KMVP@206350|Nitrosomonadales	206350|Nitrosomonadales	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS2_k127_2946076_4	1123368.AUIS01000023_gene933	6.084e-200	654.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
CMS2_k127_2946076_10	1485544.JQKP01000011_gene755	1.932e-122	404.0	COG3287@1|root,COG3287@2|Bacteria,1R825@1224|Proteobacteria,2VPKS@28216|Betaproteobacteria,44W6E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CMS2_k127_2946076_3	187272.Mlg_1393	1.008e-267	831.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales	135613|Chromatiales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CMS2_k127_2946076_21	883.DvMF_1384	1.619e-17	90.0	COG0737@1|root,COG0737@2|Bacteria,1NDBC@1224|Proteobacteria,42V2W@68525|delta/epsilon subdivisions,2X5T9@28221|Deltaproteobacteria,2MBXJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS2_k127_2946076_19	743720.Psefu_2287	3.104e-40	168.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,1YWTQ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4
CMS2_k127_2946076_11	396588.Tgr7_1860	7.24e-107	353.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1WW0K@135613|Chromatiales	135613|Chromatiales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS2_k127_2946076_9	1005395.CSV86_02362	2.918e-126	410.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1YYHQ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	V	pfam abc	yadG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_2946076_6	1278309.KB907101_gene523	1.706e-175	559.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria,1XHMN@135619|Oceanospirillales	135619|Oceanospirillales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS2_k127_2946076_7	1278309.KB907101_gene522	3.181e-162	516.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XHEF@135619|Oceanospirillales	135619|Oceanospirillales	S	ATPase, AAA	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS2_k127_2946076_13	1278309.KB907101_gene521	4.802e-94	325.0	COG3064@1|root,COG3064@2|Bacteria,1RINZ@1224|Proteobacteria,1S7TN@1236|Gammaproteobacteria,1XM41@135619|Oceanospirillales	135619|Oceanospirillales	M	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
CMS2_k127_2946076_8	1278309.KB907101_gene520	5.1e-161	521.0	28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,1RYCA@1236|Gammaproteobacteria,1XJA1@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS2_k127_2946076_15	629265.PMA4326_04826	3.791e-78	273.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,1Z9CW@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CMS2_k127_2946076_14	1278309.KB907101_gene518	4.175e-88	296.0	COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria,1XK0Q@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS2_k127_2946076_17	1278309.KB907101_gene517	2.574e-67	242.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,1SZTB@1236|Gammaproteobacteria,1XRNY@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_2946076_0	105559.Nwat_1021	0.0	1177.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase, M16	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
CMS2_k127_2983782_1	2340.JV46_28740	1.016e-155	493.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1J58G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS2_k127_2983782_5	1286106.MPL1_07313	4.708e-29	123.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,461G2@72273|Thiotrichales	72273|Thiotrichales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS2_k127_2983782_0	631362.Thi970DRAFT_01214	4.512e-182	574.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1WW13@135613|Chromatiales	135613|Chromatiales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS2_k127_2983782_2	1123393.KB891316_gene1507	1.214e-111	369.0	COG2378@1|root,COG2378@2|Bacteria,1MX81@1224|Proteobacteria,2VHKR@28216|Betaproteobacteria,1KSKE@119069|Hydrogenophilales	119069|Hydrogenophilales	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
CMS2_k127_2983782_4	472759.Nhal_1117	7.908e-44	166.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SCZX@1236|Gammaproteobacteria,1WZ3C@135613|Chromatiales	135613|Chromatiales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS2_k127_2983782_3	765910.MARPU_14760	1.165e-55	200.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1WYNA@135613|Chromatiales	135613|Chromatiales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
CMS2_k127_2983782_6	90813.JQMT01000001_gene1625	2.054e-22	98.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,45ZW4@72273|Thiotrichales	72273|Thiotrichales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS2_k127_3014642_1	335543.Sfum_3450	4.165e-159	512.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MQ4E@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS2_k127_3014642_0	519989.ECTPHS_10606	5.519e-181	579.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1WXQX@135613|Chromatiales	135613|Chromatiales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS2_k127_3061362_12	870187.Thini_2216	2.534e-35	139.0	COG3791@1|root,COG3791@2|Bacteria,1PSHH@1224|Proteobacteria,1SB5F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS2_k127_3061362_7	1121937.AUHJ01000011_gene2842	3.327e-88	297.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,4655T@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
CMS2_k127_3061362_14	350688.Clos_2132	3.071e-18	95.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,24HXX@186801|Clostridia,36VUG@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_3061362_3	1077972.ARGLB_092_00260	5.179e-157	527.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS2_k127_3061362_17	243090.RB3376	0.0008767	48.0	COG3303@1|root,COG3303@2|Bacteria,2J0SN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS2_k127_3061362_4	1198232.CYCME_0392	2.332e-115	379.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,4613M@72273|Thiotrichales	72273|Thiotrichales	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS2_k127_3061362_6	1049564.TevJSym_be00310	7.884e-103	344.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1J5AH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS2_k127_3061362_11	472759.Nhal_0344	1.005e-44	171.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1WXHN@135613|Chromatiales	135613|Chromatiales	Q	PFAM toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS2_k127_3061362_0	396588.Tgr7_0584	2.042e-218	684.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1WWN2@135613|Chromatiales	135613|Chromatiales	O	PFAM peptidase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
CMS2_k127_3061362_10	1123279.ATUS01000001_gene1426	3.345e-49	192.0	COG4872@1|root,COG4872@2|Bacteria,1NAIX@1224|Proteobacteria,1S1XV@1236|Gammaproteobacteria,1J9Q3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS2_k127_3061362_13	1168065.DOK_01334	3.496e-29	130.0	COG4929@1|root,COG4929@2|Bacteria,1NURJ@1224|Proteobacteria,1T0ZP@1236|Gammaproteobacteria,1JAM3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
CMS2_k127_3061362_2	765911.Thivi_3089	7.996e-167	532.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales	135613|Chromatiales	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS2_k127_3061362_8	519989.ECTPHS_12938	1.247e-84	286.0	COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1WY4J@135613|Chromatiales	135613|Chromatiales	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CMS2_k127_3061362_1	713586.KB900536_gene1261	4.376e-194	612.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1WX8S@135613|Chromatiales	135613|Chromatiales	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS2_k127_3061362_5	1168065.DOK_18230	4.752e-103	342.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1J5D3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726	Shikimate_DH,Shikimate_dh_N
CMS2_k127_3061362_9	1215092.PA6_016_00560	7.35e-68	235.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1YFG1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	yrdA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS2_k127_3061362_15	1485544.JQKP01000018_gene576	3.285e-17	86.0	COG0840@1|root,COG0840@2|Bacteria,1NKHI@1224|Proteobacteria,2WHPN@28216|Betaproteobacteria,44W48@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
CMS2_k127_3061362_16	1163617.SCD_n00500	8.59e-14	74.0	COG3255@1|root,COG3255@2|Bacteria,1N93W@1224|Proteobacteria,2WHTH@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
CMS2_k127_3066234_41	1049564.TevJSym_bs00010	8.055e-44	166.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1J4VV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	recombinase XerD	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS2_k127_3066234_43	1049564.TevJSym_ae00030	1.507e-38	147.0	COG0358@1|root,COG0358@2|Bacteria,1MWQW@1224|Proteobacteria	1224|Proteobacteria	L	Toprim domain	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_3
CMS2_k127_3066234_46	1348657.M622_00005	1.816e-33	148.0	COG1368@1|root,COG1368@2|Bacteria,1RG6W@1224|Proteobacteria,2VYI7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_3066234_1	1232410.KI421413_gene776	0.0	1079.0	COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria,1MWF8@1224|Proteobacteria,42PRD@68525|delta/epsilon subdivisions,2X5MX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS2_k127_3066234_20	1123368.AUIS01000003_gene1830	1.413e-133	434.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	ko:K09014	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	UPF0051
CMS2_k127_3066234_29	1123368.AUIS01000003_gene1831	6.928e-91	305.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	FeS assembly ATPase SufC	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
CMS2_k127_3066234_0	472759.Nhal_1845	0.0	1131.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,LysM
CMS2_k127_3066234_16	472759.Nhal_0216	1.017e-153	504.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1WWT6@135613|Chromatiales	135613|Chromatiales	M	Surface antigen variable number	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
CMS2_k127_3066234_9	472759.Nhal_0217	1.18e-204	682.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales	135613|Chromatiales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS2_k127_3066234_56	498761.HM1_1175	2.064e-08	57.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS2_k127_3066234_7	1283284.AZUK01000001_gene687	2.407e-226	707.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1Y44P@135624|Aeromonadales	135624|Aeromonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
CMS2_k127_3066234_24	518766.Rmar_0038	6.977e-113	376.0	COG2850@1|root,COG2850@2|Bacteria,4PEBP@976|Bacteroidetes,1FIRX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
CMS2_k127_3066234_42	1049564.TevJSym_ad01310	7.271e-41	156.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1J6CX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yjcF	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS2_k127_3066234_53	1049564.TevJSym_ad01300	1.82e-20	98.0	COG2153@1|root,COG2153@2|Bacteria,1N7TN@1224|Proteobacteria,1SCI6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein acetylation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3066234_6	472759.Nhal_2617	2.991e-240	757.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1WWJW@135613|Chromatiales	135613|Chromatiales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CMS2_k127_3066234_19	472759.Nhal_1062	1.689e-137	446.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1WW1A@135613|Chromatiales	135613|Chromatiales	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS2_k127_3066234_18	1123279.ATUS01000001_gene2592	1.457e-144	463.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1J55C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	rimK	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
CMS2_k127_3066234_40	1122197.ATWI01000008_gene3157	1.288e-49	181.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,467C1@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS2_k127_3066234_50	765913.ThidrDRAFT_0214	1.005e-28	123.0	29QAQ@1|root,30B9W@2|Bacteria,1RGQ5@1224|Proteobacteria,1S5E4@1236|Gammaproteobacteria,1WY7X@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3066234_17	1121033.AUCF01000021_gene2825	1.703e-149	483.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TUHD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS2_k127_3066234_32	396588.Tgr7_1958	3.148e-77	266.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria,1WYEW@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_3066234_15	187272.Mlg_0751	4.766e-163	530.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1X01C@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS2_k127_3066234_11	1123401.JHYQ01000002_gene2654	6.524e-178	564.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,1RSA6@1236|Gammaproteobacteria,45ZTC@72273|Thiotrichales	72273|Thiotrichales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_3066234_49	1163617.SCD_n00433	3.963e-30	123.0	2E4TM@1|root,32ZMZ@2|Bacteria,1NAT5@1224|Proteobacteria,2VXD9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3066234_48	589865.DaAHT2_0976	1.792e-32	130.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS2_k127_3066234_26	105559.Nwat_2315	2.451e-107	353.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1WXFG@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS2_k127_3066234_36	472759.Nhal_2438	7.789e-63	224.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales	135613|Chromatiales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS2_k127_3066234_23	1123279.ATUS01000005_gene3306	2.608e-115	379.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1J4EI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS2_k127_3066234_31	1191299.AJYX01000061_gene3236	8.746e-83	280.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XTPC@135623|Vibrionales	135623|Vibrionales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS2_k127_3066234_54	105559.Nwat_0675	1.569e-18	91.0	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,1WYXD@135613|Chromatiales	135613|Chromatiales	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
CMS2_k127_3066234_27	472759.Nhal_0719	1.173e-100	335.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales	135613|Chromatiales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS2_k127_3066234_3	765914.ThisiDRAFT_2309	8.641e-303	936.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1WW67@135613|Chromatiales	135613|Chromatiales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS2_k127_3066234_55	1163617.SCD_n01395	2.794e-12	70.0	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Glutaredoxin-like domain (DUF836)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836
CMS2_k127_3066234_14	472759.Nhal_0717	6.946e-170	546.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS2_k127_3066234_47	1123368.AUIS01000017_gene2572	6.109e-33	133.0	COG3086@1|root,COG3086@2|Bacteria	2|Bacteria	T	response to oxidative stress	rseC	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
CMS2_k127_3066234_35	323261.Noc_2464	2.675e-63	231.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1WWVY@135613|Chromatiales	135613|Chromatiales	T	PFAM MucB RseB	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
CMS2_k127_3066234_51	1049564.TevJSym_ah00310	3.456e-27	118.0	COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SWYJ@1236|Gammaproteobacteria,1J6IG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Anti sigma-E protein RseA, N-terminal domain	-	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
CMS2_k127_3066234_30	187272.Mlg_1339	3.583e-83	280.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1WXBZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_3066234_5	1049564.TevJSym_ah00290	3.012e-248	776.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1J59P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899	FAD_binding_2,Succ_DH_flav_C
CMS2_k127_3066234_57	765911.Thivi_4344	0.0006163	49.0	2E181@1|root,32WNM@2|Bacteria,1N2P2@1224|Proteobacteria,1SARH@1236|Gammaproteobacteria,1WYZE@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	ko:K19168	-	-	-	-	ko00000,ko02048	-	-	-	-
CMS2_k127_3066234_25	396588.Tgr7_1464	2.01e-107	358.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
CMS2_k127_3066234_33	472759.Nhal_0723	2.758e-65	235.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS2_k127_3066234_4	857087.Metme_3280	1.806e-253	789.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1XDV5@135618|Methylococcales	135618|Methylococcales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS2_k127_3066234_12	572477.Alvin_1282	5.606e-176	556.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1WWPU@135613|Chromatiales	135613|Chromatiales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS2_k127_3066234_22	396588.Tgr7_0974	1.278e-122	398.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1WXGX@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS2_k127_3066234_44	555778.Hneap_1146	1.142e-36	145.0	COG1416@1|root,COG1416@2|Bacteria,1N0U1@1224|Proteobacteria,1SGKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
CMS2_k127_3066234_10	1049564.TevJSym_ac01190	4.786e-183	578.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1J4DE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0006457,GO:0008150,GO:0009987	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS2_k127_3066234_2	713586.KB900536_gene3031	0.0	1050.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS2_k127_3066234_39	243233.MCA1857	1.614e-50	185.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1XF1X@135618|Methylococcales	135618|Methylococcales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS2_k127_3066234_21	686340.Metal_2048	1.188e-124	408.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1XDVC@135618|Methylococcales	135618|Methylococcales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CMS2_k127_3066234_28	395493.BegalDRAFT_1645	3.642e-94	317.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,460FP@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS2_k127_3066234_13	713586.KB900536_gene3027	6.581e-174	563.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CMS2_k127_3066234_37	297246.lpp0438	2.433e-59	211.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1JEBB@118969|Legionellales	118969|Legionellales	K	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS2_k127_3066234_52	1122201.AUAZ01000004_gene3385	1.261e-22	104.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,468DR@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
CMS2_k127_3066234_45	396588.Tgr7_0965	4.447e-36	140.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WZ6P@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
CMS2_k127_3066234_38	472759.Nhal_0885	1.098e-55	198.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1WY06@135613|Chromatiales	135613|Chromatiales	I	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS2_k127_3066234_8	1249627.D779_0297	8.912e-211	664.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
CMS2_k127_3066234_34	396588.Tgr7_0962	1.875e-64	224.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales	135613|Chromatiales	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS2_k127_3086373_1	358681.BBR47_11000	7.795e-116	398.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS,PAS_3,PAS_9
CMS2_k127_3086373_8	2340.JV46_04690	0.0001125	48.0	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,1SI73@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3086373_2	870187.Thini_1929	2.901e-112	379.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Inner membrane protein involved in colicin E2 resistance	creD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
CMS2_k127_3086373_0	1215092.PA6_008_00200	6.21e-145	477.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RPVU@1236|Gammaproteobacteria,1YE1K@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	creC	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031667,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07641,ko:K07711	ko02020,ko02024,map02020,map02024	M00449,M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_3,sCache_3_2
CMS2_k127_3086373_3	1323663.AROI01000006_gene2839	2.303e-80	273.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1S179@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	creB	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_3086373_5	1249627.D779_2192	2.732e-63	226.0	COG0639@1|root,COG0639@2|Bacteria,1MXN9@1224|Proteobacteria,1RYPF@1236|Gammaproteobacteria,1WXJ5@135613|Chromatiales	135613|Chromatiales	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS2_k127_3096761_1	1123279.ATUS01000001_gene1443	2.331e-110	366.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,1J4BZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
CMS2_k127_3096761_8	1232683.ADIMK_0646	4.353e-30	135.0	2C2XP@1|root,32WP3@2|Bacteria,1N3V4@1224|Proteobacteria,1SD8F@1236|Gammaproteobacteria,468UA@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3096761_9	713586.KB900536_gene1476	3.097e-27	119.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	DUF4388,GGDEF,Response_reg
CMS2_k127_3096761_0	1122599.AUGR01000002_gene3638	2.372e-132	427.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,1XHD7@135619|Oceanospirillales	135619|Oceanospirillales	DT	COG1718 Serine threonine protein kinase involved in cell cycle control	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
CMS2_k127_3096761_6	1081640.AGFU01000103_gene907	1.174e-34	142.0	COG2340@1|root,COG2340@2|Bacteria,1N566@1224|Proteobacteria,2UHNC@28211|Alphaproteobacteria,2K4VY@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM SCP-like extracellular	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS2_k127_3096761_3	396588.Tgr7_0655	2.86e-74	257.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,1WY4C@135613|Chromatiales	135613|Chromatiales	S	PFAM SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
CMS2_k127_3096761_4	1328313.DS2_03145	1.239e-65	232.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria,4657A@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
CMS2_k127_3096761_7	472759.Nhal_3164	1.399e-34	143.0	COG1842@1|root,COG1842@2|Bacteria,1N09Q@1224|Proteobacteria,1S8S2@1236|Gammaproteobacteria,1WYZ0@135613|Chromatiales	135613|Chromatiales	KT	PFAM PspA IM30	-	-	-	-	-	-	-	-	-	-	-	-	PspA_IM30
CMS2_k127_3096761_2	472759.Nhal_3163	1.355e-78	279.0	293XF@1|root,2ZRCI@2|Bacteria,1RGQW@1224|Proteobacteria,1S41W@1236|Gammaproteobacteria,1WYA0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3096761_5	261292.Nit79A3_0695	4.041e-36	138.0	2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,2W3RS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF5062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5062
CMS2_k127_3110168_10	1049564.TevJSym_at00430	6.813e-129	416.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1J4X9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS2_k127_3110168_24	2340.JV46_16300	1.262e-49	179.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1J6I8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	protein conserved in bacteria	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF971
CMS2_k127_3110168_11	396588.Tgr7_0059	8.408e-127	410.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1WWSM@135613|Chromatiales	135613|Chromatiales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS2_k127_3110168_33	715451.ambt_09910	1.791e-32	132.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria,468IV@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
CMS2_k127_3110168_26	472759.Nhal_2365	1.61e-46	175.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1WWJP@135613|Chromatiales	135613|Chromatiales	S	Sterol-binding domain protein	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
CMS2_k127_3110168_2	187272.Mlg_0071	6.063e-233	732.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales	135613|Chromatiales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS2_k127_3110168_6	395961.Cyan7425_3629	3.483e-166	535.0	COG0579@1|root,COG0579@2|Bacteria,1G4FU@1117|Cyanobacteria	1117|Cyanobacteria	C	malate quinone oxidoreductase	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
CMS2_k127_3110168_23	313628.LNTAR_17263	1.012e-50	192.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc
CMS2_k127_3110168_40	1041146.ATZB01000049_gene5503	4.79e-08	60.0	2C1W3@1|root,3018B@2|Bacteria,1P4QS@1224|Proteobacteria,2V4IR@28211|Alphaproteobacteria,4BJIG@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3110168_32	319225.Plut_1411	3.095e-35	138.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_3110168_25	192952.MM_0012	7.693e-47	171.0	COG5507@1|root,arCOG09468@2157|Archaea,2Y13Q@28890|Euryarchaeota,2NB85@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
CMS2_k127_3110168_22	765913.ThidrDRAFT_2845	1.437e-51	195.0	COG3203@1|root,COG3203@2|Bacteria,1R49B@1224|Proteobacteria,1RSFN@1236|Gammaproteobacteria,1WWR4@135613|Chromatiales	135613|Chromatiales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3110168_29	1250005.PHEL85_0796	3.147e-41	163.0	COG1409@1|root,COG1409@2|Bacteria,4NGXX@976|Bacteroidetes,1II3B@117743|Flavobacteriia,3VWZV@52959|Polaribacter	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS2_k127_3110168_43	1268240.ATFI01000003_gene5108	8.595e-06	55.0	294ZR@1|root,2ZSCK@2|Bacteria,4NNYY@976|Bacteroidetes,2FP6D@200643|Bacteroidia,4AMAA@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG27188 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3110168_41	32057.KB217483_gene9385	4.077e-07	63.0	COG5434@1|root,COG5434@2|Bacteria,1GQ4X@1117|Cyanobacteria	1117|Cyanobacteria	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS2_k127_3110168_42	1449063.JMLS01000020_gene5237	1.237e-06	61.0	COG3534@1|root,COG4733@1|root,COG3534@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	amyB3	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Glyco_hydro_18,Glyco_hydro_cc,Laminin_G_3,fn3
CMS2_k127_3110168_37	443144.GM21_1501	1.863e-15	90.0	COG1629@1|root,COG4886@1|root,COG4771@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	inlA	-	-	ko:K02014,ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.14	-	-	DUF285,FecR,LRR_4,Strep_his_triad,TPR_16
CMS2_k127_3110168_27	391615.ABSJ01000039_gene1848	1.666e-43	175.0	COG3221@1|root,COG3221@2|Bacteria,1NBWA@1224|Proteobacteria	1224|Proteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS2_k127_3110168_17	1116472.MGMO_105c00260	1.746e-81	281.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XE1M@135618|Methylococcales	135618|Methylococcales	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
CMS2_k127_3110168_35	1294143.H681_20880	4.645e-25	109.0	COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yqcC	GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF446
CMS2_k127_3110168_21	414684.RC1_3303	4.773e-55	199.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U7TT@28211|Alphaproteobacteria,2JWI6@204441|Rhodospirillales	204441|Rhodospirillales	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS2_k127_3110168_14	396588.Tgr7_2595	5.183e-105	346.0	COG1028@1|root,COG1028@2|Bacteria,1MUAY@1224|Proteobacteria,1S1XJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS2_k127_3110168_13	1260251.SPISAL_01070	5.949e-112	372.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1WWRE@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
CMS2_k127_3110168_16	1026882.MAMP_02906	7.038e-89	304.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,460I1@72273|Thiotrichales	72273|Thiotrichales	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CMS2_k127_3110168_15	1121935.AQXX01000106_gene567	2.798e-100	331.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1XH6V@135619|Oceanospirillales	135619|Oceanospirillales	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS2_k127_3110168_9	105559.Nwat_1733	7.442e-143	460.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1WW5G@135613|Chromatiales	135613|Chromatiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS2_k127_3110168_5	243233.MCA0063	4.024e-171	550.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XEP5@135618|Methylococcales	135618|Methylococcales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS2_k127_3110168_7	472759.Nhal_2204	4.631e-162	521.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales	135613|Chromatiales	S	PFAM Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS2_k127_3110168_20	765913.ThidrDRAFT_0119	5.587e-62	222.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1WY3H@135613|Chromatiales	135613|Chromatiales	L	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS2_k127_3110168_19	713586.KB900536_gene2422	7.134e-66	230.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1WY42@135613|Chromatiales	135613|Chromatiales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS2_k127_3110168_28	1163617.SCD_n02633	5.666e-43	158.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
CMS2_k127_3110168_3	323261.Noc_0769	2.805e-213	679.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS2_k127_3110168_12	768671.ThimaDRAFT_0785	1.068e-119	392.0	COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,1RQTR@1236|Gammaproteobacteria,1WWFV@135613|Chromatiales	135613|Chromatiales	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3110168_30	136993.KB900626_gene3802	3.636e-38	148.0	COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,2U7WC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	CDP-archaeol synthase	-	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
CMS2_k127_3110168_18	187272.Mlg_2077	1.193e-73	262.0	COG2199@1|root,COG3706@2|Bacteria,1N7HG@1224|Proteobacteria,1S2NP@1236|Gammaproteobacteria,1X2AA@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS2_k127_3110168_4	90813.JQMT01000001_gene20	1.81e-185	586.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,45ZXW@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS2_k127_3110168_1	396588.Tgr7_3019	4.338e-236	736.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS2_k127_3110168_0	395493.BegalDRAFT_2300	0.0	2055.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS2_k127_3110168_39	1123228.AUIH01000022_gene3096	1.862e-09	68.0	COG3266@1|root,COG3266@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,1XJX1@135619|Oceanospirillales	135619|Oceanospirillales	U	AAA domain	-	-	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
CMS2_k127_3110168_36	1163408.UU9_01889	1.68e-20	93.0	COG3831@1|root,COG3831@2|Bacteria,1NGUF@1224|Proteobacteria,1T6H3@1236|Gammaproteobacteria,1X7H4@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	WGR
CMS2_k127_3110168_8	765914.ThisiDRAFT_0941	1.782e-156	503.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS2_k127_3110168_31	631362.Thi970DRAFT_00489	4.428e-38	145.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS2_k127_3159970_0	713586.KB900536_gene1465	4.174e-302	934.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1WVYF@135613|Chromatiales	135613|Chromatiales	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS2_k127_3159970_1	1163617.SCD_n01888	1.003e-234	730.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS2_k127_3159970_8	1123354.AUDR01000013_gene729	1.774e-05	47.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,1KRC6@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Domain of unknown function (DUF3362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
CMS2_k127_3159970_5	1049564.TevJSym_by00060	4.244e-35	137.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,1SDCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3159970_4	396588.Tgr7_2713	3.358e-88	311.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS2_k127_3159970_2	589865.DaAHT2_0698	2.171e-137	447.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2MJW6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS2_k127_3159970_3	754477.Q7C_897	9.231e-126	416.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,4600Z@72273|Thiotrichales	72273|Thiotrichales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS2_k127_3159970_7	243233.MCA1366	5.217e-09	64.0	2DRM4@1|root,33C8W@2|Bacteria,1NQ8K@1224|Proteobacteria,1SGVH@1236|Gammaproteobacteria,1XFRG@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3159970_6	1073999.BN137_3415	7.268e-11	62.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	iSDY_1059.SDY_4251	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_3162816_2	1232683.ADIMK_4172	6.41e-206	645.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,4656N@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS2_k127_3162816_8	1163617.SCD_n00181	1.11e-75	258.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQ1S@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
CMS2_k127_3162816_14	398767.Glov_2264	9.892e-37	141.0	COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,42SC4@68525|delta/epsilon subdivisions,2WPHK@28221|Deltaproteobacteria,43VXI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
CMS2_k127_3162816_15	1123399.AQVE01000027_gene11	4.004e-35	138.0	COG3255@1|root,COG3255@2|Bacteria,1RI49@1224|Proteobacteria,1S38T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS2_k127_3162816_3	237368.SCABRO_02538	1.025e-159	521.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2IXNK@203682|Planctomycetes	203682|Planctomycetes	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
CMS2_k127_3162816_17	1121939.L861_01765	3.132e-30	128.0	2E8EX@1|root,332TA@2|Bacteria,1N97B@1224|Proteobacteria,1SDNS@1236|Gammaproteobacteria,1XM60@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3162816_11	290512.Paes_0154	2.084e-58	205.0	COG0824@1|root,COG0824@2|Bacteria,1FF3Z@1090|Chlorobi	1090|Chlorobi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS2_k127_3162816_4	1307437.J139_03700	1.154e-149	485.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,2Q20P@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family	speC	-	4.1.1.17,4.1.1.20	ko:K01581,ko:K01586	ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230	M00016,M00134,M00525,M00526,M00527	R00451,R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0864	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS2_k127_3162816_18	1121921.KB898706_gene2476	5.086e-18	87.0	2CEDU@1|root,333S9@2|Bacteria,1NCM4@1224|Proteobacteria,1SDI0@1236|Gammaproteobacteria,2PP29@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4156
CMS2_k127_3162816_1	686340.Metal_3624	4.744e-283	877.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XEME@135618|Methylococcales	135618|Methylococcales	S	pfam abc	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_3162816_0	713586.KB900536_gene2437	0.0	1080.0	COG0642@1|root,COG0784@1|root,COG3614@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WVYT@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg
CMS2_k127_3162816_22	292415.Tbd_1667	3.022e-10	63.0	2EJVT@1|root,33DKI@2|Bacteria,1NKVD@1224|Proteobacteria,2W5WE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3162816_23	713587.THITH_07030	3.243e-07	53.0	2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3096
CMS2_k127_3162816_9	105559.Nwat_0146	9.393e-74	254.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1WWMM@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS2_k127_3162816_13	882378.RBRH_03843	5.03e-40	157.0	COG0352@1|root,COG0352@2|Bacteria,1QTX7@1224|Proteobacteria,2WGGK@28216|Betaproteobacteria,1K7X7@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS2_k127_3162816_16	1163617.SCD_n00546	3.534e-31	126.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3162816_10	414684.RC1_1514	2.321e-63	231.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS2_k127_3162816_6	251221.35212217	4.668e-147	479.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS2_k127_3162816_20	1120960.ATXG01000001_gene981	2.428e-13	80.0	COG3971@1|root,COG3971@2|Bacteria,2GM4Z@201174|Actinobacteria,4FRFR@85023|Microbacteriaceae	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.1.1.77	ko:K01617	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R02602,R05374	RC00751,RC02672	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
CMS2_k127_3162816_5	1304865.JAGF01000001_gene89	9.592e-148	477.0	COG2265@1|root,COG2265@2|Bacteria,2GP90@201174|Actinobacteria,4F24B@85016|Cellulomonadaceae	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumB	-	2.1.1.189	ko:K03212	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
CMS2_k127_3162816_7	1349767.GJA_254	3.513e-104	345.0	COG3541@1|root,COG3541@2|Bacteria,1MYFT@1224|Proteobacteria,2VJ6B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
CMS2_k127_3162816_19	243090.RB4921	4.506e-15	84.0	2DNAV@1|root,32WHG@2|Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS2_k127_3162816_21	1121935.AQXX01000057_gene1925	7.072e-13	76.0	COG4969@1|root,COG4969@2|Bacteria,1QWD5@1224|Proteobacteria,1S3WU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CMS2_k127_3162816_24	342610.Patl_3343	5.905e-06	58.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,2Q0BD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	U	COG1459 Type II secretory pathway, component PulF	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS2_k127_3162816_12	349521.HCH_06933	4.79e-51	185.0	COG4969@1|root,COG4969@2|Bacteria,1N4MN@1224|Proteobacteria,1S7ZB@1236|Gammaproteobacteria,1XR13@135619|Oceanospirillales	135619|Oceanospirillales	NU	Pilin (bacterial filament)	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CMS2_k127_3163077_8	1242864.D187_006025	1.041e-73	267.0	COG1404@1|root,COG3291@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YZ9E@29|Myxococcales	28221|Deltaproteobacteria	OQ	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
CMS2_k127_3163077_13	406124.ACPC01000014_gene818	9.537e-07	59.0	291YW@1|root,2ZPID@2|Bacteria,1V3V6@1239|Firmicutes,4HGYJ@91061|Bacilli,1ZG6E@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2621)	yneK	-	-	-	-	-	-	-	-	-	-	-	DUF2621
CMS2_k127_3163077_1	1255043.TVNIR_1634	4.112e-290	906.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CK	Regulator of nitric oxide reductase transcription	nosR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4,Fer4_5
CMS2_k127_3163077_0	1255043.TVNIR_1638	5e-324	1000.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria,1WZYX@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c oxidase subunit	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	COX2,Cupredoxin_1
CMS2_k127_3163077_4	1255043.TVNIR_1635	1.387e-172	551.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria,1X14E@135613|Chromatiales	135613|Chromatiales	P	Periplasmic copper-binding protein (NosD)	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
CMS2_k127_3163077_6	1255043.TVNIR_1636	1.765e-111	367.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RY6M@1236|Gammaproteobacteria,1X2CF@135613|Chromatiales	135613|Chromatiales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
CMS2_k127_3163077_5	713587.THITH_08430	1.408e-112	371.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria,1X1TK@135613|Chromatiales	135613|Chromatiales	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
CMS2_k127_3163077_10	1397528.Q671_00405	2.33e-38	153.0	COG4314@1|root,COG4314@2|Bacteria,1RCDR@1224|Proteobacteria,1SZSY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM NosL family protein	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS2_k127_3163077_12	1122197.ATWI01000010_gene860	8.812e-28	119.0	2CBGR@1|root,32YXQ@2|Bacteria,1N8AR@1224|Proteobacteria,1SCE0@1236|Gammaproteobacteria,468MS@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3163077_9	1121374.KB891576_gene593	3.291e-45	167.0	COG2832@1|root,COG2832@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF454)	ybaN	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
CMS2_k127_3163077_7	1469613.JT55_04300	9.426e-99	330.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2U40G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS2_k127_3163077_3	1469613.JT55_04295	2.215e-181	593.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2TR5T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
CMS2_k127_3163077_11	1348657.M622_03135	2.665e-29	119.0	2DRNM@1|root,33CDS@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
CMS2_k127_3163077_2	67373.JOBF01000004_gene883	2.851e-246	803.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
CMS2_k127_3175288_5	1397527.Q670_07730	2.799e-14	73.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1XIG5@135619|Oceanospirillales	135619|Oceanospirillales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3175288_7	1123053.AUDG01000025_gene258	9.711e-12	65.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1WX1R@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS2_k127_3175288_6	1129794.C427_4676	8.448e-12	66.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS2_k127_3175288_1	324602.Caur_3520	1.015e-95	327.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,Response_reg,dCache_1
CMS2_k127_3175288_4	1121935.AQXX01000058_gene1949	2.431e-27	113.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1XIH1@135619|Oceanospirillales	135619|Oceanospirillales	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS2_k127_3175288_0	1165841.SULAR_03053	1.456e-130	428.0	COG2191@1|root,COG2191@2|Bacteria,1NX7R@1224|Proteobacteria,430UJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	-	-	-	-	-	-	-	-	-	-	FmdE
CMS2_k127_3175288_2	290397.Adeh_2713	1.501e-40	174.0	COG5492@1|root,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,42UE8@68525|delta/epsilon subdivisions,2WVIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
CMS2_k127_3175288_8	1144310.PMI07_005783	1.204e-07	66.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,4BGGI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
CMS2_k127_3175288_9	404380.Gbem_0381	6.809e-05	57.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CMS2_k127_3175288_3	1291050.JAGE01000001_gene2238	5.005e-28	133.0	COG3055@1|root,COG4733@1|root,COG3055@2|Bacteria,COG4733@2|Bacteria,1V5WF@1239|Firmicutes,24H47@186801|Clostridia	186801|Clostridia	N	PFAM Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1
CMS2_k127_3188052_2	1158165.KB898871_gene2107	8.178e-55	200.0	COG3642@1|root,COG3642@2|Bacteria,1QWT7@1224|Proteobacteria,1T2XM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
CMS2_k127_3188052_0	748658.KB907316_gene525	2.414e-130	425.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X2HB@135613|Chromatiales	135613|Chromatiales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS2_k127_3188052_1	1166948.JPZL01000004_gene64	4.647e-107	372.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XMBH@135619|Oceanospirillales	135619|Oceanospirillales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_3188052_3	1122179.KB890491_gene4425	8.715e-12	65.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1IQ5C@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS2_k127_3199003_7	519989.ECTPHS_12637	1.482e-73	257.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S49E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	glutamine amidotransferase	guaA_2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS2_k127_3199003_12	589865.DaAHT2_0205	6.919e-32	128.0	COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,42TRA@68525|delta/epsilon subdivisions,2WR3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3199003_14	4432.XP_010261393.1	1.682e-06	59.0	2AJBI@1|root,2RZ6Q@2759|Eukaryota,37UHN@33090|Viridiplantae,3GIQ7@35493|Streptophyta	35493|Streptophyta	S	Desiccation protectant protein Lea14 homolog	-	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006952,GO:0008150,GO:0009314,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009620,GO:0009628,GO:0009642,GO:0009644,GO:0016020,GO:0043207,GO:0044424,GO:0044444,GO:0044464,GO:0048046,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0071944,GO:0098542	-	-	-	-	-	-	-	-	-	-	LEA_2
CMS2_k127_3199003_11	1049564.TevJSym_bb00350	1.596e-44	165.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1JBM2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CMS2_k127_3199003_13	765911.Thivi_4563	5.581e-26	110.0	COG2920@1|root,COG2920@2|Bacteria,1N6BZ@1224|Proteobacteria,1S8YA@1236|Gammaproteobacteria,1WYWH@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS2_k127_3199003_2	1207063.P24_09306	4.845e-128	416.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2TRRU@28211|Alphaproteobacteria,2JQ4F@204441|Rhodospirillales	204441|Rhodospirillales	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
CMS2_k127_3199003_8	1121921.KB898706_gene2488	3.962e-69	244.0	2910Q@1|root,2ZNNC@2|Bacteria,1PCP3@1224|Proteobacteria,1S0BX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3199003_5	1298593.TOL_2972	9.617e-91	308.0	COG3770@1|root,COG3770@2|Bacteria,1PXYG@1224|Proteobacteria,1RQ4F@1236|Gammaproteobacteria,1XJDU@135619|Oceanospirillales	135619|Oceanospirillales	M	Penicillin-insensitive murein endopeptidase	-	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
CMS2_k127_3199003_3	697282.Mettu_3840	1.348e-124	410.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,1T1PC@1236|Gammaproteobacteria,1XERZ@135618|Methylococcales	135618|Methylococcales	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
CMS2_k127_3199003_0	857087.Metme_2061	2.17e-272	855.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XEIC@135618|Methylococcales	135618|Methylococcales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
CMS2_k127_3199003_1	748247.AZKH_0279	9.541e-137	449.0	COG2159@1|root,COG2159@2|Bacteria,1R7E1@1224|Proteobacteria,2VPY4@28216|Betaproteobacteria,2KVED@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
CMS2_k127_3199003_10	1123355.JHYO01000017_gene3573	6.665e-45	169.0	COG1309@1|root,COG1309@2|Bacteria,1N0XU@1224|Proteobacteria,2U82V@28211|Alphaproteobacteria,36YQ2@31993|Methylocystaceae	28211|Alphaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS2_k127_3199003_4	1049564.TevJSym_aj00660	2.376e-100	329.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1J6CP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	PhnA domain	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
CMS2_k127_3199003_6	1177181.T9A_02339	6.13e-90	301.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1XH39@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS2_k127_3199003_9	396588.Tgr7_3236	1.226e-65	225.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1WW65@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS2_k127_3213149_0	713586.KB900536_gene1843	1.491e-198	629.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1WWD1@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS2_k127_3213149_1	1049564.TevJSym_ac02050	1.38e-182	588.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1J4QZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS2_k127_3213149_6	1049564.TevJSym_ac02040	3.513e-52	188.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1J67Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Yqey-like protein	lporfX	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS2_k127_3213149_8	440512.C211_09336	3.961e-24	103.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS2_k127_3213149_2	1121878.AUGL01000019_gene1558	4.692e-161	514.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS2_k127_3213149_4	572477.Alvin_1834	6.263e-65	227.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1WWMS@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS2_k127_3213149_7	930169.B5T_00967	3.313e-48	175.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS2_k127_3213149_5	395493.BegalDRAFT_2719	3.379e-58	207.0	COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,462T1@72273|Thiotrichales	72273|Thiotrichales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS2_k127_3213149_3	395493.BegalDRAFT_2870	3.405e-94	315.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,461ZC@72273|Thiotrichales	72273|Thiotrichales	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS2_k127_3216412_4	396588.Tgr7_1002	1.092e-222	700.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS2_k127_3216412_1	396588.Tgr7_1003	1.343e-317	994.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
CMS2_k127_3216412_20	396588.Tgr7_1004	1.442e-39	150.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales	135613|Chromatiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS2_k127_3216412_8	1049564.TevJSym_ap00430	1.054e-109	362.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1J4X5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
CMS2_k127_3216412_23	1279015.KB908466_gene36	5.219e-36	138.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1Y4NR@135624|Aeromonadales	135624|Aeromonadales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS2_k127_3216412_0	765912.Thimo_0707	5e-323	1000.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS2_k127_3216412_13	857087.Metme_4606	8.161e-79	268.0	COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1XDKT@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS2_k127_3216412_14	697282.Mettu_2015	3.024e-77	262.0	COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1XF09@135618|Methylococcales	135618|Methylococcales	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
CMS2_k127_3216412_11	686340.Metal_3598	1.115e-85	289.0	COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,1XE85@135618|Methylococcales	135618|Methylococcales	C	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS2_k127_3216412_12	323261.Noc_0989	1.012e-83	281.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS2_k127_3216412_29	301.JNHE01000013_gene2822	1.801e-11	70.0	2EJCN@1|root,33D3N@2|Bacteria,1NIQR@1224|Proteobacteria,1SGNQ@1236|Gammaproteobacteria,1YGY0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3216412_6	1038922.PflQ2_4876	1.092e-118	395.0	COG0671@1|root,COG2453@1|root,COG0671@2|Bacteria,COG2453@2|Bacteria,1QSUD@1224|Proteobacteria,1RQAC@1236|Gammaproteobacteria,1YP9K@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	IT	Dual specificity phosphatase, catalytic domain	ynbD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	DAGK_cat,DSPc,PAP2_3
CMS2_k127_3216412_2	1120999.JONM01000008_gene2070	1.685e-258	809.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VNMX@28216|Betaproteobacteria,2KQI2@206351|Neisseriales	206351|Neisseriales	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Methyltransf_20
CMS2_k127_3216412_15	1005999.GLGR_1793	1.247e-75	259.0	COG0204@1|root,COG0204@2|Bacteria,1RA8V@1224|Proteobacteria,1S4RP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS2_k127_3216412_5	794903.OPIT5_06810	6.432e-119	392.0	COG4589@1|root,COG4589@2|Bacteria,46T6E@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS2_k127_3216412_16	1214065.BAGV01000008_gene3381	5.732e-60	213.0	COG0558@1|root,COG0558@2|Bacteria,1RE0I@1224|Proteobacteria,1S2UQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	CDP-alcohol phosphatidyltransferase	ynbA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS2_k127_3216412_10	1163617.SCD_n00464	1.748e-91	312.0	28Q1D@1|root,2ZCJS@2|Bacteria,1RF11@1224|Proteobacteria,2VQZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3216412_24	1132855.KB913035_gene1585	3.363e-35	135.0	COG4309@1|root,COG4309@2|Bacteria,1N4MS@1224|Proteobacteria,2VU7H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
CMS2_k127_3216412_19	1454004.AW11_01333	1.03e-40	156.0	2CM31@1|root,32SD0@2|Bacteria,1N2TZ@1224|Proteobacteria,2VUNK@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3216412_9	1163617.SCD_n00446	5.334e-93	318.0	COG4243@1|root,COG4243@2|Bacteria,1MW9C@1224|Proteobacteria,2VPG2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3216412_25	1163617.SCD_n00448	9.925e-28	116.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VUA0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS2_k127_3216412_22	1122194.AUHU01000006_gene616	8.664e-39	151.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria,467Q8@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Transcriptional regulator	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
CMS2_k127_3216412_26	522306.CAP2UW1_3552	1.107e-22	104.0	COG5592@1|root,COG5592@2|Bacteria,1N4TJ@1224|Proteobacteria,2VU5X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS2_k127_3216412_28	1207075.PputUW4_02091	8.714e-13	73.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ANAPC5,Peptidase_C39_2,TPR_16,TPR_19,TPR_2,TPR_8
CMS2_k127_3216412_17	1122197.ATWI01000008_gene2775	9.987e-48	182.0	2EBDF@1|root,335E4@2|Bacteria,1NH7B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4878
CMS2_k127_3216412_18	1122185.N792_13130	9.279e-44	166.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S28H@1236|Gammaproteobacteria,1X3DX@135614|Xanthomonadales	135614|Xanthomonadales	M	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	yjbJ	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
CMS2_k127_3216412_21	640512.BC1003_2970	2.474e-39	151.0	COG2764@1|root,COG2764@2|Bacteria,1N6GB@1224|Proteobacteria,2WEHT@28216|Betaproteobacteria,1K7BG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_3216412_3	1318628.MARLIPOL_10786	1.541e-237	745.0	COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,1T3BC@1236|Gammaproteobacteria,465YW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
CMS2_k127_3216412_7	1479237.JMLY01000001_gene591	1.038e-111	368.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,1S87G@1236|Gammaproteobacteria,46DNW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
CMS2_k127_3257582_35	396588.Tgr7_1155	6.793e-47	171.0	COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1WYT7@135613|Chromatiales	135613|Chromatiales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS2_k127_3257582_11	396588.Tgr7_1153	3.418e-186	588.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1WWET@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_3257582_15	1123401.JHYQ01000022_gene1089	1.562e-149	476.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,45ZN7@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CMS2_k127_3257582_37	396588.Tgr7_1151	4.326e-46	169.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,1WYR9@135613|Chromatiales	135613|Chromatiales	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
CMS2_k127_3257582_12	1232683.ADIMK_1184	2.783e-178	565.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,4650N@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_3257582_29	1123514.KB905899_gene1994	8.512e-67	237.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,1S0KZ@1236|Gammaproteobacteria,463AF@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
CMS2_k127_3257582_18	1026882.MAMP_02682	1.4e-147	474.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,4602Y@72273|Thiotrichales	72273|Thiotrichales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_3257582_9	395493.BegalDRAFT_1743	6.041e-207	652.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,45ZS3@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS2_k127_3257582_39	1430440.MGMSRv2_0136	4.282e-40	160.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,2JS06@204441|Rhodospirillales	204441|Rhodospirillales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
CMS2_k127_3257582_20	204773.HEAR2554	1.583e-121	404.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2VNVS@28216|Betaproteobacteria,4759G@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS2_k127_3257582_47	1445613.JALM01000049_gene5584	0.0009684	46.0	COG0458@1|root,COG0458@2|Bacteria,2GKXY@201174|Actinobacteria,4E1ZY@85010|Pseudonocardiales	201174|Actinobacteria	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
CMS2_k127_3257582_46	1283300.ATXB01000002_gene3164	1.998e-09	61.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase S15	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS2_k127_3257582_27	1120963.KB894500_gene70	2.135e-86	295.0	COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,2PZWI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,TPR_19,TPR_8
CMS2_k127_3257582_6	1123279.ATUS01000001_gene2267	3.059e-212	668.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,1J5EI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ACT domain	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
CMS2_k127_3257582_32	552811.Dehly_1308	2.386e-57	203.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
CMS2_k127_3257582_5	472759.Nhal_2707	2.878e-221	692.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1WXFB@135613|Chromatiales	135613|Chromatiales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_3257582_34	377629.TERTU_3382	1.239e-48	179.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,2PNS2@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) family	ectA	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS2_k127_3257582_36	930169.B5T_00887	1.129e-46	173.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XK3K@135619|Oceanospirillales	135619|Oceanospirillales	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS2_k127_3257582_17	396588.Tgr7_3240	1.258e-148	475.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1WWCG@135613|Chromatiales	135613|Chromatiales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
CMS2_k127_3257582_7	675806.VII_003450	3.63e-209	658.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XT9Q@135623|Vibrionales	135623|Vibrionales	F	Belongs to the GARS family	purD	GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS2_k127_3257582_10	929558.SMGD1_2852	1.689e-202	652.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42Q3N@68525|delta/epsilon subdivisions,2YMVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_3257582_23	637905.SVI_1691	9.932e-99	338.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
CMS2_k127_3257582_2	1049564.TevJSym_ao00430	1.253e-271	843.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1J4DF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcHS_1320.EcHS_A4240,iPC815.YPO3728	AICARFT_IMPCHas,MGS
CMS2_k127_3257582_43	1177179.A11A3_14320	2.671e-24	104.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XKMB@135619|Oceanospirillales	135619|Oceanospirillales	K	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
CMS2_k127_3257582_16	323848.Nmul_A0131	3.543e-149	478.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,371XV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS2_k127_3257582_42	1211579.PP4_48860	6.79e-31	139.0	COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1YX1V@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
CMS2_k127_3257582_21	743720.Psefu_4015	1.202e-105	351.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1YV0U@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS2_k127_3257582_3	396588.Tgr7_0368	2.472e-244	759.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1WWPY@135613|Chromatiales	135613|Chromatiales	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS2_k127_3257582_33	519989.ECTPHS_06037	3.262e-56	199.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1WY9Z@135613|Chromatiales	135613|Chromatiales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS2_k127_3257582_31	1265313.HRUBRA_02568	1.405e-60	213.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1J5YM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0560	DHquinase_II
CMS2_k127_3257582_4	765911.Thivi_1096	5.359e-240	762.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS2_k127_3257582_41	765912.Thimo_0178	9.122e-32	126.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1WYXG@135613|Chromatiales	135613|Chromatiales	P	Divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CMS2_k127_3257582_40	1283300.ATXB01000001_gene809	3.864e-33	134.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1XF3Y@135618|Methylococcales	135618|Methylococcales	S	PFAM FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
CMS2_k127_3257582_38	1121935.AQXX01000074_gene693	8.858e-44	163.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XKHD@135619|Oceanospirillales	135619|Oceanospirillales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS2_k127_3257582_1	396588.Tgr7_0439	1.335e-291	902.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales	135613|Chromatiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS2_k127_3257582_0	472759.Nhal_0173	7.035e-316	994.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales	135613|Chromatiales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS2_k127_3257582_13	105559.Nwat_0125	1.546e-170	538.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1WW7W@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS2_k127_3257582_45	1123518.ARWI01000001_gene2003	3.362e-19	88.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	VL23_05015	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
CMS2_k127_3257582_44	1122212.AULO01000007_gene2542	6.155e-21	106.0	COG3307@1|root,COG3307@2|Bacteria,1R8PC@1224|Proteobacteria,1RYYV@1236|Gammaproteobacteria,1XM5Y@135619|Oceanospirillales	135619|Oceanospirillales	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
CMS2_k127_3257582_8	931627.MycrhDRAFT_3462	2.794e-208	657.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2GKU1@201174|Actinobacteria,232S7@1762|Mycobacteriaceae	201174|Actinobacteria	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB,SIS_2
CMS2_k127_3257582_14	931627.MycrhDRAFT_3461	1.574e-164	527.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS2_k127_3257582_25	1301098.PKB_5298	2.35e-89	304.0	COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,1RQYV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_3257582_19	62928.azo3565	5.532e-131	426.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS2_k127_3257582_22	290398.Csal_0011	3.674e-102	338.0	COG0463@1|root,COG0463@2|Bacteria,1RE4C@1224|Proteobacteria,1SJQD@1236|Gammaproteobacteria,1XR8Y@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS2_k127_3257582_26	709032.Sulku_2130	2.075e-88	304.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2YQJT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CMS2_k127_3257582_24	42565.FP66_02755	7.364e-93	317.0	COG0859@1|root,COG0859@2|Bacteria,1N5A1@1224|Proteobacteria,1RYYI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ADP-heptose LPS heptosyltransferase	waaQ	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CMS2_k127_3257582_30	55601.VANGNB10_cI2538c	4.095e-62	226.0	COG1216@1|root,COG1216@2|Bacteria,1QV95@1224|Proteobacteria,1T2AK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
CMS2_k127_3257582_28	225937.HP15_2387	3.371e-78	263.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,46A45@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Male sterility protein	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS2_k127_3343951_3	187272.Mlg_2637	3.797e-82	289.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales	135613|Chromatiales	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N,Kdo
CMS2_k127_3343951_1	589865.DaAHT2_0590	2.003e-113	375.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria,2MK0N@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS2_k127_3343951_6	1485544.JQKP01000003_gene98	3.554e-29	124.0	COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,2VUY4@28216|Betaproteobacteria,44WHW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS2_k127_3343951_2	1049564.TevJSym_ar00230	6.556e-113	379.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1J52S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS2_k127_3343951_4	472759.Nhal_3506	6.779e-71	248.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales	135613|Chromatiales	O	PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS2_k127_3343951_0	391615.ABSJ01000005_gene602	2.134e-321	992.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1J51V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c45100	ThiC-associated,ThiC_Rad_SAM
CMS2_k127_3343951_5	545264.KB898745_gene1352	5.949e-45	170.0	COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,1S6W5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS2_k127_3343951_7	1123401.JHYQ01000047_gene168	3.727e-28	118.0	COG5331@1|root,COG5331@2|Bacteria,1N7DJ@1224|Proteobacteria,1SCVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS2_k127_3357102_10	493475.GARC_2664	2.852e-75	260.0	COG4977@1|root,COG4977@2|Bacteria,1RCIG@1224|Proteobacteria,1S2SH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
CMS2_k127_3357102_9	1297865.APJD01000018_gene5738	4.435e-84	293.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2U0CV@28211|Alphaproteobacteria,3JX3A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
CMS2_k127_3357102_4	561229.Dd1591_3131	2.684e-183	597.0	COG2175@1|root,COG3207@1|root,COG2175@2|Bacteria,COG3207@2|Bacteria,1RJYX@1224|Proteobacteria,1S7ZT@1236|Gammaproteobacteria,2JD2J@204037|Dickeya	1236|Gammaproteobacteria	Q	Pyoverdine/dityrosine biosynthesis protein	pvcA	-	-	-	-	-	-	-	-	-	-	-	DIT1_PvcA,TauD
CMS2_k127_3357102_16	1298593.TOL_3186	6.429e-31	141.0	COG3453@1|root,COG3453@2|Bacteria,1PZ54@1224|Proteobacteria,1TKD3@1236|Gammaproteobacteria,1XQAE@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
CMS2_k127_3357102_6	1177154.Y5S_02218	8.094e-142	459.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1XIII@135619|Oceanospirillales	135619|Oceanospirillales	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS2_k127_3357102_8	1316927.ATKI01000070_gene1219	1.218e-99	335.0	COG3207@1|root,COG3207@2|Bacteria,1R4R2@1224|Proteobacteria,1RQMJ@1236|Gammaproteobacteria,1YSY0@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	Q	Pyoverdine/dityrosine biosynthesis protein	pvcA	-	-	-	-	-	-	-	-	-	-	-	DIT1_PvcA
CMS2_k127_3357102_22	398767.Glov_0520	8.698e-08	55.0	COG3464@1|root,COG3464@2|Bacteria,1R4DH@1224|Proteobacteria,43AQ4@68525|delta/epsilon subdivisions,2X63W@28221|Deltaproteobacteria,43W3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
CMS2_k127_3357102_17	1121937.AUHJ01000036_gene2807	2.122e-28	116.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,4640P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
CMS2_k127_3357102_18	1121937.AUHJ01000036_gene2807	1.364e-12	68.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,4640P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
CMS2_k127_3357102_20	1027273.GZ77_05505	5.797e-10	60.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,1RQQA@1236|Gammaproteobacteria,1XKYJ@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
CMS2_k127_3357102_0	555778.Hneap_2282	0.0	1042.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1WZW2@135613|Chromatiales	135613|Chromatiales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD_5
CMS2_k127_3357102_14	323850.Shew_2603	1.774e-51	185.0	COG4551@1|root,COG4551@2|Bacteria,1N05F@1224|Proteobacteria,1TAXB@1236|Gammaproteobacteria,2QCSD@267890|Shewanellaceae	1236|Gammaproteobacteria	S	low molecular weight phosphotyrosine protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3357102_11	228410.NE0717	9.258e-70	241.0	COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,2VQXP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
CMS2_k127_3357102_3	697282.Mettu_1941	4.21e-191	614.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,1RP1I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	GO:0000302,GO:0001505,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0017144,GO:0034641,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0044237,GO:0044248,GO:0044270,GO:0046209,GO:0046210,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748,GO:2001057	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
CMS2_k127_3357102_19	1298593.TOL_0031	1.469e-12	74.0	COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1SA3I@1236|Gammaproteobacteria,1XJWR@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
CMS2_k127_3357102_12	1008459.TASI_0680	1.09e-68	234.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,3T3MV@506|Alcaligenaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS2_k127_3357102_15	265072.Mfla_0519	3.199e-48	181.0	COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria,2KNEN@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
CMS2_k127_3357102_13	1123073.KB899241_gene2732	4.406e-66	235.0	COG0596@1|root,COG0596@2|Bacteria,1QTWQ@1224|Proteobacteria,1T1JQ@1236|Gammaproteobacteria,1XDB2@135614|Xanthomonadales	135614|Xanthomonadales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS2_k127_3357102_5	1122194.AUHU01000005_gene971	8.217e-176	576.0	COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae	1236|Gammaproteobacteria	EMT	Bacterial periplasmic substrate-binding proteins	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
CMS2_k127_3357102_7	572477.Alvin_0488	4.257e-107	354.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS2_k127_3357102_1	713586.KB900536_gene674	2.025e-241	752.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1WWIR@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS2_k127_3357102_2	1249627.D779_3925	1.665e-226	717.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales	135613|Chromatiales	I	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS2_k127_3467216_3	1224318.DT73_16915	2.688e-81	278.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_3467216_1	472759.Nhal_0236	1.694e-114	379.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1WVZX@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
CMS2_k127_3467216_2	1115512.EH105704_02_04680	2.133e-99	331.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,3XN7M@561|Escherichia	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine. TcdA is also part of a sulfur transfer pathway	ygdL	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
CMS2_k127_3467216_4	439235.Dalk_4843	2.706e-81	289.0	2B3X8@1|root,31WM6@2|Bacteria,1RFRT@1224|Proteobacteria,42SXT@68525|delta/epsilon subdivisions,2WPT2@28221|Deltaproteobacteria,2MKBX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
CMS2_k127_3467216_0	1121405.dsmv_0222	2.651e-240	770.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,42NMF@68525|delta/epsilon subdivisions,2WIJ2@28221|Deltaproteobacteria,2MIRD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS2_k127_3489118_18	648757.Rvan_0599	1.006e-10	62.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2U3RE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sulfite reductase	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS2_k127_3489118_0	1049564.TevJSym_aw00210	1.988e-226	705.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type alpha subunit	dsrA	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS2_k127_3489118_11	1049564.TevJSym_aw00240	9.012e-80	273.0	COG0457@1|root,COG0457@2|Bacteria,1R85G@1224|Proteobacteria,1S0MD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3489118_12	1049564.TevJSym_aw00250	2.54e-69	241.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM CRISPR-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
CMS2_k127_3489118_15	396588.Tgr7_2181	6.321e-43	159.0	COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria,1WYQ6@135613|Chromatiales	135613|Chromatiales	P	Part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS2_k127_3489118_1	187272.Mlg_0220	1.944e-150	488.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1S1NC@1236|Gammaproteobacteria,1X06R@135613|Chromatiales	135613|Chromatiales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_3489118_3	713586.KB900536_gene937	9.88e-128	424.0	COG4191@1|root,COG4191@2|Bacteria,1QVHZ@1224|Proteobacteria,1S2DC@1236|Gammaproteobacteria,1WZY5@135613|Chromatiales	135613|Chromatiales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_3489118_8	1123368.AUIS01000008_gene2164	3.592e-95	321.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,2NBTW@225057|Acidithiobacillales	1236|Gammaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS2_k127_3489118_4	392500.Swoo_2793	7.767e-107	357.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S473@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
CMS2_k127_3489118_7	395494.Galf_1879	1.041e-98	334.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,SBP_bac_3,dCache_1
CMS2_k127_3489118_19	859657.RPSI07_2634	9.408e-06	54.0	2BHV9@1|root,32BZ1@2|Bacteria,1R02D@1224|Proteobacteria,2WHSQ@28216|Betaproteobacteria,1K7EP@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3489118_6	1163617.SCD_n02495	1.201e-99	336.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,2VZZT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3489118_16	412965.COSY_0906	8.034e-29	123.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,1RS8I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3489118_10	1049564.TevJSym_bc00200	1.498e-81	276.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1J5UI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c13120,ic_1306.c1370	Thymidylate_kin
CMS2_k127_3489118_13	857087.Metme_3486	3.383e-69	246.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1XDVJ@135618|Methylococcales	135618|Methylococcales	L	DNA polymerase III, delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS2_k127_3489118_14	1323663.AROI01000009_gene3637	1.73e-53	190.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	pilus assembly protein, PilZ	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
CMS2_k127_3489118_5	395493.BegalDRAFT_0348	4.699e-104	343.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,460G9@72273|Thiotrichales	72273|Thiotrichales	L	Hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS2_k127_3489118_9	391615.ABSJ01000026_gene110	1.211e-83	289.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	PT	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
CMS2_k127_3489118_2	1283300.ATXB01000001_gene1756	1.01e-145	471.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,1XDRB@135618|Methylococcales	135618|Methylococcales	E	PFAM Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS2_k127_3512029_0	713586.KB900536_gene91	8.685e-281	876.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
CMS2_k127_3512029_21	292415.Tbd_2476	2.858e-32	131.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3512029_12	1255043.TVNIR_0850	2.614e-99	330.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria,1WVZM@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
CMS2_k127_3512029_4	1266914.ATUK01000012_gene216	8.183e-166	529.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales	135613|Chromatiales	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS2_k127_3512029_8	1255043.TVNIR_1787	2.502e-134	436.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glycosyl transferase	ybiB	GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS2_k127_3512029_3	1163617.SCD_n02706	1.044e-168	544.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CMS2_k127_3512029_23	765913.ThidrDRAFT_2023	1.783e-27	117.0	COG0316@1|root,COG0316@2|Bacteria,1RKPC@1224|Proteobacteria,1SB76@1236|Gammaproteobacteria,1WYKT@135613|Chromatiales	135613|Chromatiales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS2_k127_3512029_10	713586.KB900536_gene997	2.679e-129	432.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1WWX3@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3
CMS2_k127_3512029_14	396588.Tgr7_2171	3.843e-87	292.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1WWCR@135613|Chromatiales	135613|Chromatiales	K	response regulator receiver	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS2_k127_3512029_24	187272.Mlg_1801	9.728e-25	111.0	2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,1X1CC@135613|Chromatiales	135613|Chromatiales	S	Peptidoglycan-binding protein, CsiV	-	-	-	-	-	-	-	-	-	-	-	-	CsiV
CMS2_k127_3512029_11	519989.ECTPHS_12983	5.946e-111	363.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1WWNN@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	-	-	2.4.2.28,2.4.2.44	ko:K00772,ko:K19696	ko00270,ko01100,map00270,map01100	M00034	R01402,R09668	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS2_k127_3512029_19	765914.ThisiDRAFT_0456	8.468e-67	233.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1WWQX@135613|Chromatiales	135613|Chromatiales	F	phosphoribosyltransferase	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS2_k127_3512029_7	1049564.TevJSym_ah00980	2.092e-144	467.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1J51T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	ynaI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS2_k127_3512029_9	1049564.TevJSym_ah00550	2.133e-132	430.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1J5G8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790	Glyco_hydro_3
CMS2_k127_3512029_18	754476.Q7A_1514	8.305e-67	233.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,460TV@72273|Thiotrichales	72273|Thiotrichales	S	PFAM L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS2_k127_3512029_17	349124.Hhal_1263	1.735e-68	237.0	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,1WYAI@135613|Chromatiales	135613|Chromatiales	S	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
CMS2_k127_3512029_20	640081.Dsui_3258	9.207e-46	171.0	COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,2VTSM@28216|Betaproteobacteria,2KWJF@206389|Rhodocyclales	206389|Rhodocyclales	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS2_k127_3512029_13	626887.J057_23360	7.514e-99	331.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,4649D@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS2_k127_3512029_22	1255043.TVNIR_1547	6.841e-32	128.0	2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,1S9KI@1236|Gammaproteobacteria,1X104@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3512029_5	1286106.MPL1_09917	8.852e-164	526.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,45ZUG@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS2_k127_3512029_6	396588.Tgr7_1100	8.652e-158	502.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1WX3I@135613|Chromatiales	135613|Chromatiales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS2_k127_3512029_25	1492922.GY26_01740	1.177e-12	72.0	COG0642@1|root,COG3437@1|root,COG0642@2|Bacteria,COG3437@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07678,ko:K20974	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg,dCache_1
CMS2_k127_3512029_2	1163617.SCD_n00988	2.912e-183	578.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2VPZ0@28216|Betaproteobacteria	28216|Betaproteobacteria	G	deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
CMS2_k127_3512029_16	653733.Selin_1904	2.108e-72	253.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,PG_binding_1,YkuD
CMS2_k127_3512029_15	558884.JRGM01000015_gene2477	6.381e-87	295.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1Y46C@135624|Aeromonadales	135624|Aeromonadales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
CMS2_k127_3512029_1	305700.B447_02501	6.193e-186	590.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,2VKEY@28216|Betaproteobacteria,2KUB3@206389|Rhodocyclales	206389|Rhodocyclales	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
CMS2_k127_3513696_3	511062.GU3_09530	5.726e-38	147.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1Y5WJ@135624|Aeromonadales	135624|Aeromonadales	S	Phosphate-starvation-inducible E	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
CMS2_k127_3513696_1	1049564.TevJSym_av00170	6.099e-234	730.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1J547@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iEC042_1314.EC042_2616	tRNA-synt_1c
CMS2_k127_3513696_0	768671.ThimaDRAFT_3728	1.74e-278	865.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1WW7Z@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS2_k127_3513696_6	1408444.JHYC01000008_gene1427	5.795e-18	84.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3513696_7	1408444.JHYC01000008_gene1427	5.069e-06	48.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3513696_8	1158182.KB905022_gene1090	0.0003134	46.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales	135613|Chromatiales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3513696_2	555778.Hneap_1517	2.211e-70	239.0	COG0454@1|root,COG0456@2|Bacteria,1RKJA@1224|Proteobacteria,1T1ZP@1236|Gammaproteobacteria,1X1TJ@135613|Chromatiales	135613|Chromatiales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS2_k127_3513696_5	1255043.TVNIR_2320	7.823e-20	91.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CMS2_k127_3513696_4	870187.Thini_2190	3.044e-33	132.0	COG0607@1|root,COG0607@2|Bacteria,1RHUS@1224|Proteobacteria,1S3ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_3581462_12	754476.Q7A_248	8.749e-35	136.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales	72273|Thiotrichales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS2_k127_3581462_4	323261.Noc_3012	1.82e-125	412.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales	135613|Chromatiales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS2_k127_3581462_10	472759.Nhal_3813	2.982e-57	203.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1WYZ6@135613|Chromatiales	135613|Chromatiales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
CMS2_k127_3581462_0	1049564.TevJSym_ag01090	0.0	1168.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1J526@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS2_k127_3581462_8	595494.Tola_0158	5.748e-71	244.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1Y48K@135624|Aeromonadales	135624|Aeromonadales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS2_k127_3581462_9	472759.Nhal_3464	4.137e-61	215.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1WY2S@135613|Chromatiales	135613|Chromatiales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
CMS2_k127_3581462_3	1397528.Q671_14065	5.208e-157	499.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS2_k127_3581462_2	754476.Q7A_877	1.886e-166	538.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales	72273|Thiotrichales	L	Exonuclease C-terminal	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
CMS2_k127_3581462_1	216595.PFLU_2676	1.864e-169	542.0	COG1222@1|root,COG1222@2|Bacteria,1NI7U@1224|Proteobacteria,1RY0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
CMS2_k127_3581462_13	216595.PFLU_2677	1.566e-33	135.0	2FBPK@1|root,343UK@2|Bacteria,1NZUR@1224|Proteobacteria,1SRN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3581462_7	216595.PFLU_2678	2.589e-77	269.0	COG0457@1|root,COG0457@2|Bacteria,1NPAW@1224|Proteobacteria,1SHZA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS2_k127_3581462_11	626887.J057_17140	2.422e-38	151.0	2A2KE@1|root,30QYM@2|Bacteria,1P2YQ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
CMS2_k127_3581462_6	626887.J057_17135	7.171e-81	282.0	COG3766@1|root,COG3766@2|Bacteria,1Q8XV@1224|Proteobacteria,1T1F5@1236|Gammaproteobacteria,46D26@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
CMS2_k127_3581462_5	626887.J057_17120	8.057e-112	369.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,1T22N@1236|Gammaproteobacteria,4671G@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS2_k127_3614402_7	545264.KB898748_gene1526	1.711e-07	58.0	2AAM4@1|root,30ZYM@2|Bacteria,1RGIM@1224|Proteobacteria,1SETC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
CMS2_k127_3614402_1	1163617.SCD_n00016	5.275e-125	405.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS2_k127_3614402_2	1049564.TevJSym_bk00180	2.007e-123	399.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1J4G1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS2_k127_3614402_0	1049564.TevJSym_bk00170	3.202e-176	565.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1J4FS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1030 Membrane-bound serine protease (ClpP class)	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
CMS2_k127_3614402_4	713586.KB900536_gene1992	3.754e-89	301.0	COG1352@1|root,COG1352@2|Bacteria,1RDBE@1224|Proteobacteria	1224|Proteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS2_k127_3614402_3	1049564.TevJSym_bf00250	3.178e-96	342.0	COG2304@1|root,COG3509@1|root,COG4257@1|root,COG2304@2|Bacteria,COG3509@2|Bacteria,COG4257@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1J904@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,FG-GAP_2
CMS2_k127_3614402_6	713586.KB900537_gene3294	1.283e-13	85.0	COG1879@1|root,COG1879@2|Bacteria,1MYP5@1224|Proteobacteria,1S84T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
CMS2_k127_3650840_7	1205908.AKXW01000146_gene1765	1.093e-194	612.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XV0G@135623|Vibrionales	135623|Vibrionales	F	carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS2_k127_3650840_0	472759.Nhal_3709	0.0	1704.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales	135613|Chromatiales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS2_k127_3650840_18	187272.Mlg_1980	1.442e-67	235.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales	135613|Chromatiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS2_k127_3650840_26	159087.Daro_0941	4.613e-23	107.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria,2KWU0@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
CMS2_k127_3650840_25	572477.Alvin_1648	3.729e-24	106.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1S67P@1236|Gammaproteobacteria,1X2GP@135613|Chromatiales	135613|Chromatiales	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
CMS2_k127_3650840_15	322710.Avin_42900	1.763e-84	286.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS2_k127_3650840_1	1249627.D779_0578	0.0	1010.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales	135613|Chromatiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS2_k127_3650840_11	105559.Nwat_0552	4.855e-112	368.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS2_k127_3650840_8	323261.Noc_2567	1.123e-187	595.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1WW1H@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS2_k127_3650840_12	2340.JV46_20250	2.325e-107	353.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1J5PU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS2_k127_3650840_24	1333856.L686_23075	1.542e-24	107.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1Z30X@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	U	Preprotein translocase subunit SecG	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS2_k127_3650840_20	187272.Mlg_1970	1.151e-56	200.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,1WYJ8@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS2_k127_3650840_13	1005048.CFU_1592	2.52e-96	316.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,473FT@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS2_k127_3650840_14	472759.Nhal_3698	2.213e-85	287.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1WWDD@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS2_k127_3650840_4	582744.Msip34_0674	4.598e-244	757.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,2KMAZ@206350|Nitrosomonadales	206350|Nitrosomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS2_k127_3650840_17	1049564.TevJSym_ap00580	3.302e-71	246.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1J746@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS2_k127_3650840_6	1026882.MAMP_00786	2.269e-230	717.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,45ZSD@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS2_k127_3650840_3	396588.Tgr7_0992	3.412e-263	832.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS2_k127_3650840_10	1049564.TevJSym_ap00550	1.62e-150	484.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1J5UV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS2_k127_3650840_16	1163617.SCD_n00947	1.123e-81	274.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS2_k127_3650840_19	519989.ECTPHS_07082	3.025e-65	228.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,1WXHS@135613|Chromatiales	135613|Chromatiales	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS2_k127_3650840_22	765913.ThidrDRAFT_4120	1.124e-44	164.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,1WYHG@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS2_k127_3650840_2	1049564.TevJSym_ap00510	2.999e-283	884.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1J4U3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CP	CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341,ko:K05559	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS2_k127_3650840_5	2340.JV46_20400	7.519e-239	747.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1J5MF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase subunit	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS2_k127_3650840_9	472759.Nhal_3687	1.783e-185	591.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS2_k127_3650840_23	519989.ECTPHS_07107	2.815e-31	125.0	2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,1SDWS@1236|Gammaproteobacteria,1X22K@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2818)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2818
CMS2_k127_3650840_27	247633.GP2143_00482	1.99e-09	63.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_3650840_21	523791.Kkor_0303	2.237e-53	192.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XJNA@135619|Oceanospirillales	135619|Oceanospirillales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS2_k127_3650840_28	765914.ThisiDRAFT_1473	1.08e-08	56.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS2_k127_37891_9	1177154.Y5S_02632	1.221e-32	127.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales	135619|Oceanospirillales	K	cold-shock protein	cspG	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_37891_0	1123279.ATUS01000002_gene17	1.792e-317	987.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1J4WH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0514 Superfamily II DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS2_k127_37891_6	305700.B447_20820	1.302e-72	249.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2WFQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS2_k127_37891_2	459495.SPLC1_S208030	2.382e-126	426.0	COG0501@1|root,COG0501@2|Bacteria,1G4ET@1117|Cyanobacteria,1HAFB@1150|Oscillatoriales	1117|Cyanobacteria	O	Peptidase family M48	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS2_k127_37891_7	279714.FuraDRAFT_0533	2.687e-38	153.0	COG3637@1|root,COG3637@2|Bacteria,1N7U7@1224|Proteobacteria,2VRRF@28216|Betaproteobacteria,2KTSV@206351|Neisseriales	206351|Neisseriales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OmpA_membrane
CMS2_k127_37891_3	713586.KB900536_gene2300	2.485e-121	398.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,1RQKY@1236|Gammaproteobacteria,1X0XH@135613|Chromatiales	135613|Chromatiales	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
CMS2_k127_37891_8	411154.GFO_1391	1.31e-33	133.0	COG3189@1|root,COG3189@2|Bacteria,4NSFD@976|Bacteroidetes,1I42N@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
CMS2_k127_37891_5	1123392.AQWL01000001_gene1512	1.393e-86	292.0	COG1018@1|root,COG1018@2|Bacteria,1R5YD@1224|Proteobacteria,2WEVH@28216|Betaproteobacteria,1KSPZ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
CMS2_k127_37891_4	396588.Tgr7_1058	4.817e-99	331.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1X0BZ@135613|Chromatiales	135613|Chromatiales	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS2_k127_37891_10	1380387.JADM01000004_gene2862	6.98e-31	124.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales	135619|Oceanospirillales	K	cold-shock protein	cspG	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_37891_13	448385.sce2902	6.079e-12	70.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
CMS2_k127_37891_1	314345.SPV1_04443	7.229e-161	520.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
CMS2_k127_37891_11	1089551.KE386572_gene3747	2.52e-29	122.0	COG1846@1|root,COG1846@2|Bacteria,1MZXE@1224|Proteobacteria,2U7TP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS2_k127_3947079_4	396588.Tgr7_0335	3.181e-12	70.0	COG4775@1|root,COG4775@2|Bacteria,1N5IS@1224|Proteobacteria,1SB24@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CMS2_k127_3947079_2	713586.KB900536_gene1215	1.523e-90	306.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1WWMK@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_3947079_1	713586.KB900536_gene72	1.056e-119	395.0	COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria,1WX5T@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
CMS2_k127_3947079_0	396588.Tgr7_0333	1.038e-194	617.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WWMQ@135613|Chromatiales	135613|Chromatiales	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_3947079_3	396588.Tgr7_0332	1.99e-42	158.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales	135613|Chromatiales	GM	NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
CMS2_k127_398609_4	2340.JV46_27580	1.92e-112	366.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	ttrA	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K08357,ko:K21307	ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020	-	R10149,R10150,R11487	RC00168,RC02823,RC03109	ko00000,ko00001,ko01000,ko02000	5.A.3.10,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
CMS2_k127_398609_2	2340.JV46_27590	1.793e-133	432.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1J9UJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7,Molydop_binding
CMS2_k127_398609_3	1163617.SCD_n01211	3.272e-126	411.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
CMS2_k127_398609_0	768671.ThimaDRAFT_1689	9.677e-216	675.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
CMS2_k127_398609_6	1049564.TevJSym_af00680	1.798e-31	130.0	2ED3M@1|root,3370H@2|Bacteria,1NB6I@1224|Proteobacteria,1SSEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_398609_1	545276.KB898732_gene2480	2.613e-160	510.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS2_k127_398609_5	1265505.ATUG01000001_gene4540	9.257e-64	224.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,42R8D@68525|delta/epsilon subdivisions,2WN83@28221|Deltaproteobacteria,2MJPW@213118|Desulfobacterales	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS2_k127_398609_8	909663.KI867150_gene478	5.678e-07	57.0	2CF4Z@1|root,330XB@2|Bacteria,1NIZ5@1224|Proteobacteria,42WR5@68525|delta/epsilon subdivisions,2WS24@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
CMS2_k127_398609_7	1026882.MAMP_02575	1.919e-25	111.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,46005@72273|Thiotrichales	72273|Thiotrichales	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS2_k127_4089727_3	713587.THITH_04180	2.321e-62	219.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1WZ06@135613|Chromatiales	135613|Chromatiales	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
CMS2_k127_4089727_0	1165841.SULAR_07380	2.58e-231	735.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,42PUG@68525|delta/epsilon subdivisions,2YN09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB-dependent copper receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS2_k127_4089727_1	1123519.PSJM300_01345	1.802e-89	300.0	COG1573@1|root,COG1573@2|Bacteria,1RBR1@1224|Proteobacteria,1RZ8U@1236|Gammaproteobacteria,1Z08N@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	uracil-DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	UDG
CMS2_k127_4089727_2	1195236.CTER_3382	1.642e-67	239.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,3WGBY@541000|Ruminococcaceae	186801|Clostridia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS2_k127_4100226_6	1122223.KB890688_gene1648	1.553e-86	290.0	COG0288@1|root,COG0288@2|Bacteria,1WKSX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS2_k127_4100226_1	1122201.AUAZ01000006_gene3881	1.851e-284	878.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,464GS@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
CMS2_k127_4100226_7	305900.GV64_09180	4.666e-85	290.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1XHTX@135619|Oceanospirillales	135619|Oceanospirillales	M	Phospholipase	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
CMS2_k127_4100226_5	1260251.SPISAL_01275	7.162e-112	366.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WWV1@135613|Chromatiales	135613|Chromatiales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS2_k127_4100226_0	472759.Nhal_0455	9.132e-317	981.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1WW1J@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS2_k127_4100226_4	1163617.SCD_n02729	2.282e-121	398.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
CMS2_k127_4100226_2	1123368.AUIS01000031_gene1420	8.092e-209	664.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales	225057|Acidithiobacillales	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS2_k127_4100226_8	1121459.AQXE01000009_gene491	5.326e-61	218.0	28NH4@1|root,2ZBJ2@2|Bacteria,1N1V3@1224|Proteobacteria,42TAP@68525|delta/epsilon subdivisions,2WQ9D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4100226_3	396588.Tgr7_0127	2.443e-201	635.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS2_k127_4100226_9	1485544.JQKP01000018_gene576	1.001e-16	83.0	COG0840@1|root,COG0840@2|Bacteria,1NKHI@1224|Proteobacteria,2WHPN@28216|Betaproteobacteria,44W48@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
CMS2_k127_4103297_62	458817.Shal_3224	4.032e-51	183.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,2QBMX@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS2_k127_4103297_38	713586.KB900536_gene1136	2.178e-105	349.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales	135613|Chromatiales	P	PFAM CBS domain	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
CMS2_k127_4103297_15	472759.Nhal_3897	2.29e-165	535.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales	135613|Chromatiales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS2_k127_4103297_68	519989.ECTPHS_03041	5.928e-43	163.0	COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1RYIB@1236|Gammaproteobacteria,1WW9G@135613|Chromatiales	135613|Chromatiales	J	Zinc-ribbon containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
CMS2_k127_4103297_1	396588.Tgr7_2279	0.0	1208.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1WW5E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS2_k127_4103297_75	519989.ECTPHS_03031	5.155e-23	106.0	COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1WY80@135613|Chromatiales	135613|Chromatiales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
CMS2_k127_4103297_40	396588.Tgr7_2277	4.733e-104	350.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1WWRB@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
CMS2_k127_4103297_9	1163617.SCD_n00056	4.736e-202	635.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS2_k127_4103297_82	1266925.JHVX01000009_gene107	7.099e-14	83.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2W44P@28216|Betaproteobacteria,374N1@32003|Nitrosomonadales	28216|Betaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K07288,ko:K08086	-	-	-	-	ko00000	-	-	-	-
CMS2_k127_4103297_55	323261.Noc_2661	1.087e-68	242.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS2_k127_4103297_69	519989.ECTPHS_03011	3.258e-40	152.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1WYQV@135613|Chromatiales	135613|Chromatiales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS2_k127_4103297_56	1049564.TevJSym_ak00660	2.466e-67	231.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1J6C3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CMS2_k127_4103297_57	1260251.SPISAL_07225	1.597e-61	218.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1WY2J@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS2_k127_4103297_6	545276.KB898725_gene577	1.055e-208	659.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS2_k127_4103297_24	396588.Tgr7_2270	1.854e-135	474.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1WXQJ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
CMS2_k127_4103297_33	396588.Tgr7_2268	1.856e-118	386.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales	135613|Chromatiales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS2_k127_4103297_67	1415778.JQMM01000001_gene824	1.248e-44	168.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1J6MQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0307 family	yjgA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
CMS2_k127_4103297_18	472759.Nhal_0326	7.237e-160	516.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1WW0B@135613|Chromatiales	135613|Chromatiales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS2_k127_4103297_11	472759.Nhal_0327	6.924e-187	601.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1WWBU@135613|Chromatiales	135613|Chromatiales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS2_k127_4103297_73	713586.KB900536_gene1424	4.073e-28	116.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1WYUA@135613|Chromatiales	135613|Chromatiales	G	Phosphotransferase System	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS2_k127_4103297_70	519989.ECTPHS_01654	6.264e-35	139.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,1WYYD@135613|Chromatiales	135613|Chromatiales	G	system, fructose subfamily IIA component	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
CMS2_k127_4103297_44	765912.Thimo_2765	3.698e-97	326.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales	135613|Chromatiales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS2_k127_4103297_47	713586.KB900536_gene1421	4.131e-91	309.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1WX9F@135613|Chromatiales	135613|Chromatiales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CMS2_k127_4103297_64	187272.Mlg_2232	1.545e-49	180.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1WYAA@135613|Chromatiales	135613|Chromatiales	G	PTS IIA-like nitrogen-regulatory protein PtsN	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS2_k127_4103297_66	395493.BegalDRAFT_2838	5.261e-45	165.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,46133@72273|Thiotrichales	72273|Thiotrichales	J	Sigma 54 modulation protein	yhbH	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS2_k127_4103297_12	157783.LK03_01625	5.519e-178	571.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS2_k127_4103297_37	1121935.AQXX01000136_gene4065	1.414e-112	367.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1XI7T@135619|Oceanospirillales	135619|Oceanospirillales	S	ABC transporter ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS2_k127_4103297_74	1042375.AFPL01000025_gene1178	1.039e-24	111.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,467V4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	lptA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065	OstA
CMS2_k127_4103297_85	768671.ThimaDRAFT_1392	3.96e-12	74.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,1S3S8@1236|Gammaproteobacteria,1WYAW@135613|Chromatiales	135613|Chromatiales	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
CMS2_k127_4103297_52	1049564.TevJSym_ak00850	1.743e-77	262.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1J685@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECO26_1355.ECO26_4302	Hydrolase_3
CMS2_k127_4103297_23	519989.ECTPHS_01704	1.554e-137	444.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1WWFJ@135613|Chromatiales	135613|Chromatiales	M	Arabinose 5-phosphate isomerase	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS2_k127_4103297_86	1158760.AQXP01000048_gene1123	1.435e-11	66.0	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,1SD0H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
CMS2_k127_4103297_36	314345.SPV1_11011	3.534e-116	382.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria	1224|Proteobacteria	P	COG0530 Ca2 Na antiporter	yrbG	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0008150,GO:0008273,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015081,GO:0015085,GO:0015267,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022803,GO:0022804,GO:0022821,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030955,GO:0031224,GO:0031226,GO:0031402,GO:0031420,GO:0034220,GO:0035725,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070588,GO:0070838,GO:0071804,GO:0071805,GO:0071944,GO:0072503,GO:0072507,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	iAPECO1_1312.APECO1_3239,iECABU_c1320.ECABU_c36110,iECNA114_1301.ECNA114_3275,iECOK1_1307.ECOK1_3617,iECS88_1305.ECS88_3578,iECSF_1327.ECSF_3028,iUMN146_1321.UM146_00400,iUTI89_1310.UTI89_C3632,ic_1306.c3956	Na_Ca_ex
CMS2_k127_4103297_53	1163617.SCD_n01213	1.393e-76	266.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria	28216|Betaproteobacteria	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CMS2_k127_4103297_78	498211.CJA_1626	3.906e-20	91.0	2E4UA@1|root,32ZNM@2|Bacteria,1NAZR@1224|Proteobacteria,1SC82@1236|Gammaproteobacteria,1FHQY@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4103297_84	1049564.TevJSym_ag00270	8.959e-13	76.0	COG1801@1|root,COG1801@2|Bacteria,1NJGC@1224|Proteobacteria,1SHUQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4103297_27	243233.MCA1969	4.405e-131	424.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XET4@135618|Methylococcales	135618|Methylococcales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS2_k127_4103297_30	1026882.MAMP_01634	5.39e-122	395.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS2_k127_4103297_58	754477.Q7C_1644	4.698e-57	202.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,460SM@72273|Thiotrichales	72273|Thiotrichales	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS2_k127_4103297_59	323261.Noc_2782	4.192e-54	197.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1WXHN@135613|Chromatiales	135613|Chromatiales	Q	PFAM toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS2_k127_4103297_79	323261.Noc_2783	3.146e-19	91.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1WZDQ@135613|Chromatiales	135613|Chromatiales	S	NTP binding protein (Contains STAS domain)	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
CMS2_k127_4103297_81	1121939.L861_00580	1.048e-15	81.0	COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,1XKZ8@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS2_k127_4103297_8	243233.MCA1965	1.514e-203	642.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1XE8B@135618|Methylococcales	135618|Methylococcales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS2_k127_4103297_41	396588.Tgr7_0743	2.817e-101	334.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1WX3P@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
CMS2_k127_4103297_3	754477.Q7C_1638	1.775e-218	685.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,460BB@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS2_k127_4103297_16	1499686.BN1079_01635	4.826e-164	522.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_4103297_26	713586.KB900536_gene1398	9.417e-134	436.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	ko:K04691	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS2_k127_4103297_45	1278309.KB907099_gene2403	2.706e-93	312.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1XIMF@135619|Oceanospirillales	135619|Oceanospirillales	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS2_k127_4103297_50	870187.Thini_1052	6.924e-81	274.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,460ET@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
CMS2_k127_4103297_4	1026882.MAMP_01410	9.571e-215	672.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS2_k127_4103297_39	1049564.TevJSym_ag00070	2.19e-104	344.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1J7JW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
CMS2_k127_4103297_51	1166948.JPZL01000001_gene2433	2.741e-80	273.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XI89@135619|Oceanospirillales	135619|Oceanospirillales	O	Stringent starvation protein A	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N,GST_N_3
CMS2_k127_4103297_65	697282.Mettu_0171	2.093e-45	168.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XFC6@135618|Methylococcales	135618|Methylococcales	S	PFAM Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
CMS2_k127_4103297_10	713586.KB900536_gene1391	2.123e-194	616.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WXBN@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD linked oxidase domain protein	-	-	1.1.5.12	ko:K03777	ko00620,ko01120,map00620,map01120	-	R00704,R11591	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS2_k127_4103297_49	1452718.JBOY01000066_gene2385	1.015e-83	281.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271,ko:K12961	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005,ko03036	-	-	-	SIS_2
CMS2_k127_4103297_72	472759.Nhal_0474	2.008e-29	124.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1WZJZ@135613|Chromatiales	135613|Chromatiales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS2_k127_4103297_29	472759.Nhal_0475	1.142e-124	422.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales	135613|Chromatiales	M	PFAM LppC	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
CMS2_k127_4103297_42	1122599.AUGR01000016_gene2884	2.93e-101	337.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XHFQ@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS2_k127_4103297_71	440512.C211_08439	2.336e-33	134.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4103297_61	1027273.GZ77_16760	6.342e-53	190.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1XJJI@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS2_k127_4103297_32	1042375.AFPL01000008_gene3153	1.728e-119	391.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS2_k127_4103297_77	314278.NB231_05631	2.456e-20	95.0	COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,1WZ00@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
CMS2_k127_4103297_5	396588.Tgr7_0763	1.26e-214	681.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS2_k127_4103297_21	472759.Nhal_0485	6.196e-151	493.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1WX75@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_4103297_22	105559.Nwat_0223	1.053e-137	451.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1WWTC@135613|Chromatiales	135613|Chromatiales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_4103297_13	1109445.AGSX01000193_gene454	4.845e-176	559.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1Z0QG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
CMS2_k127_4103297_19	472759.Nhal_0488	1.678e-156	505.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS2_k127_4103297_25	396588.Tgr7_0768	4.344e-135	440.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS2_k127_4103297_31	626887.J057_04115	9.832e-120	401.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,464K0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
CMS2_k127_4103297_7	519989.ECTPHS_01879	1.15e-203	644.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1WW6B@135613|Chromatiales	135613|Chromatiales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS2_k127_4103297_35	713586.KB900536_gene1371	1.125e-117	386.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS2_k127_4103297_28	1485544.JQKP01000002_gene1623	3.486e-129	420.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS2_k127_4103297_63	472759.Nhal_0494	7.533e-50	188.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1X2GI@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS2_k127_4103297_2	1049564.TevJSym_aj00250	1.711e-219	685.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1J4FB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS2_k127_4103297_14	396588.Tgr7_0775	1.739e-173	552.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS2_k127_4103297_20	396588.Tgr7_0776	2.966e-154	491.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1WW5R@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
CMS2_k127_4103297_83	1042876.PPS_4349	1.963e-13	76.0	COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1SDJY@1236|Gammaproteobacteria,1YYRR@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS2_k127_4103297_46	1121374.KB891588_gene3401	9.721e-92	311.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_4103297_48	643867.Ftrac_2909	1.542e-88	306.0	COG2843@1|root,COG2843@2|Bacteria,4NI6J@976|Bacteroidetes,47NKK@768503|Cytophagia	976|Bacteroidetes	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS2_k127_4103297_0	105559.Nwat_0237	0.0	1321.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS2_k127_4103297_17	1396858.Q666_08865	4.107e-161	516.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,464AB@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS2_k127_4103297_43	472759.Nhal_3853	3.733e-99	335.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1WW2I@135613|Chromatiales	135613|Chromatiales	HL	Thiamine monophosphate synthase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4,TMP-TENI
CMS2_k127_4103297_76	323261.Noc_0308	1.659e-20	93.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,1WZTU@135613|Chromatiales	135613|Chromatiales	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
CMS2_k127_4103297_54	472759.Nhal_3851	1.654e-74	258.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales	135613|Chromatiales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
CMS2_k127_4103297_60	1283300.ATXB01000001_gene1290	2.376e-53	199.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1XF4I@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS2_k127_4103297_34	754476.Q7A_644	5.902e-118	385.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,460AW@72273|Thiotrichales	72273|Thiotrichales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS2_k127_414959_4	1121396.KB892904_gene4247	4.962e-154	499.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2MJA8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS2_k127_414959_2	519989.ECTPHS_03382	5.187e-194	616.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXUS@135613|Chromatiales	135613|Chromatiales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_414959_7	748247.AZKH_3888	8.016e-68	233.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2VPZP@28216|Betaproteobacteria,2KW26@206389|Rhodocyclales	206389|Rhodocyclales	P	iron-storage protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS2_k127_414959_10	545695.TREAZ_0585	1.284e-59	225.0	COG5360@1|root,COG5360@2|Bacteria,2J6PR@203691|Spirochaetes	203691|Spirochaetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_414959_8	933262.AXAM01000043_gene1183	2.295e-65	230.0	COG1842@1|root,COG1842@2|Bacteria,1R9BF@1224|Proteobacteria,42NZU@68525|delta/epsilon subdivisions,2WMMD@28221|Deltaproteobacteria,2MMDX@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS2_k127_414959_1	1215092.PA6_037_00510	1.945e-194	640.0	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YE8V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
CMS2_k127_414959_9	765914.ThisiDRAFT_1638	7.141e-60	217.0	COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1RY54@1236|Gammaproteobacteria,1WWFU@135613|Chromatiales	135613|Chromatiales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase
CMS2_k127_414959_11	870187.Thini_0352	2.505e-55	201.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,1S6X5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM NifZ	nifZ	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
CMS2_k127_414959_17	870187.Thini_0353	1.979e-26	111.0	2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,1S999@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	May protect the nitrogenase Fe-Mo protein from oxidative damage	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
CMS2_k127_414959_12	580332.Slit_0809	8.571e-44	164.0	COG0457@1|root,COG0457@2|Bacteria,1R714@1224|Proteobacteria,2VRZB@28216|Betaproteobacteria,44WD3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_414959_6	580332.Slit_0808	1.633e-103	344.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VMGF@28216|Betaproteobacteria,44WCG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	nifP	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS2_k127_414959_3	519989.ECTPHS_05200	2.621e-158	507.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RRGA@1236|Gammaproteobacteria,1WX0C@135613|Chromatiales	135613|Chromatiales	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
CMS2_k127_414959_0	765911.Thivi_0485	8.786e-216	674.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1WWHG@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS2_k127_414959_5	765913.ThidrDRAFT_0031	6.38e-149	475.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1WW3I@135613|Chromatiales	135613|Chromatiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
CMS2_k127_414959_13	580332.Slit_0804	1.372e-35	138.0	COG0316@1|root,COG0316@2|Bacteria,1MZTE@1224|Proteobacteria,2VUJT@28216|Betaproteobacteria,44WGU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
CMS2_k127_414959_16	1323663.AROI01000006_gene2802	3.668e-27	112.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1SCBE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein	IV02_09080	-	-	-	-	-	-	-	-	-	-	-	VF530
CMS2_k127_414959_15	697282.Mettu_1419	3.355e-29	123.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1XFY6@135618|Methylococcales	135618|Methylococcales	S	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS2_k127_4163751_20	1049564.TevJSym_ad00660	2.564e-94	313.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,1J5Q7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
CMS2_k127_4163751_22	1121035.AUCH01000003_gene1335	2.128e-73	255.0	COG0614@1|root,COG0614@2|Bacteria,1NS57@1224|Proteobacteria,2VZ4D@28216|Betaproteobacteria,2KXYK@206389|Rhodocyclales	206389|Rhodocyclales	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4163751_26	1121015.N789_08875	8.211e-69	239.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1X50D@135614|Xanthomonadales	135614|Xanthomonadales	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS2_k127_4163751_33	932678.THERU_02025	7.49e-14	80.0	COG0810@1|root,COG0810@2|Bacteria,2G5C3@200783|Aquificae	200783|Aquificae	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_4163751_15	314278.NB231_10373	6.157e-106	365.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1WWF7@135613|Chromatiales	135613|Chromatiales	H	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
CMS2_k127_4163751_14	643562.Daes_3078	7.876e-111	389.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS2_k127_4163751_9	572477.Alvin_0601	9.594e-136	457.0	COG1629@1|root,COG4771@2|Bacteria,1RKNG@1224|Proteobacteria,1RQYA@1236|Gammaproteobacteria,1WVXK@135613|Chromatiales	135613|Chromatiales	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS2_k127_4163751_27	1298593.TOL_3644	1.119e-62	225.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
CMS2_k127_4163751_34	1390370.O203_15310	4.39e-05	46.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1YHK4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	subunit of a heme lyase	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS2_k127_4163751_25	640081.Dsui_0531	3.227e-70	248.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VRFJ@28216|Betaproteobacteria,2KW3Z@206389|Rhodocyclales	206389|Rhodocyclales	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS2_k127_4163751_12	1504981.KO116_2038	2.658e-113	376.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XIU2@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS2_k127_4163751_21	396588.Tgr7_2416	3.677e-94	313.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1WXJF@135613|Chromatiales	135613|Chromatiales	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS2_k127_4163751_23	187272.Mlg_0427	3.068e-72	247.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales	135613|Chromatiales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
CMS2_k127_4163751_1	396588.Tgr7_2414	1.12e-282	888.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales	135613|Chromatiales	T	Belongs to the PEP-utilizing enzyme family	-	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS2_k127_4163751_18	498761.HM1_1715	4.618e-100	333.0	COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,25E75@186801|Clostridia	186801|Clostridia	L	Site-specific DNA-methyltransferase (Adenine-specific)	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
CMS2_k127_4163751_5	1163617.SCD_n02840	1.377e-181	578.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
CMS2_k127_4163751_6	396588.Tgr7_0573	8.976e-170	542.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1WX3F@135613|Chromatiales	135613|Chromatiales	E	Belongs to the peptidase M20A family. ArgE subfamily	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS2_k127_4163751_8	396588.Tgr7_0574	8.392e-146	471.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
CMS2_k127_4163751_3	713586.KB900536_gene1553	2.956e-187	596.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales	135613|Chromatiales	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,RLAN,RimK
CMS2_k127_4163751_4	396588.Tgr7_2589	1.976e-185	604.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
CMS2_k127_4163751_32	243231.GSU1054	7.201e-20	95.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K07112	-	-	-	-	ko00000	-	-	-	HTH_20,HTH_5,TusA
CMS2_k127_4163751_11	396588.Tgr7_2590	6.623e-128	418.0	COG0425@1|root,COG2391@1|root,COG0425@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085,ko:K07112	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	HTH_20,HTH_5,Sulf_transp,TusA
CMS2_k127_4163751_31	1121035.AUCH01000006_gene684	5.407e-23	104.0	COG0840@1|root,COG0840@2|Bacteria,1PGTY@1224|Proteobacteria,2WB5T@28216|Betaproteobacteria,2KZDD@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
CMS2_k127_4163751_16	1286631.X805_31890	1.694e-104	354.0	COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,2VXGN@28216|Betaproteobacteria,1KNG2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MP	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	OmpA,PBP_like_2
CMS2_k127_4163751_13	587753.EY04_19705	6.35e-113	378.0	COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MP	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	OmpA,PBP_like_2
CMS2_k127_4163751_0	870187.Thini_2404	0.0	1033.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS2_k127_4163751_19	713586.KB900536_gene1599	3.462e-97	324.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1WVZG@135613|Chromatiales	135613|Chromatiales	T	phosphate regulon transcriptional regulatory protein PhoB	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_4163751_10	519989.ECTPHS_12943	7.521e-133	436.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1WWCF@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
CMS2_k127_4163751_7	491952.Mar181_3498	4.146e-151	483.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1XH4P@135619|Oceanospirillales	135619|Oceanospirillales	P	Phosphate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS2_k127_4163751_29	519989.ECTPHS_08076	6.947e-31	125.0	COG1734@1|root,COG1734@2|Bacteria,1N7D8@1224|Proteobacteria	1224|Proteobacteria	T	COG1734 DnaK suppressor protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS2_k127_4163751_2	1123228.AUIH01000008_gene2387	2.524e-246	768.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XHA7@135619|Oceanospirillales	135619|Oceanospirillales	P	Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS2_k127_4163751_17	237609.PSAKL28_31600	6.907e-101	336.0	COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS2_k127_4163751_24	1123368.AUIS01000009_gene2445	3.497e-72	252.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,1S4TA@1236|Gammaproteobacteria,2NDAZ@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS2_k127_4163751_28	272134.KB731324_gene6257	2.626e-59	214.0	COG1451@1|root,COG1451@2|Bacteria,1G6GG@1117|Cyanobacteria,1HB3P@1150|Oscillatoriales	1117|Cyanobacteria	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CMS2_k127_4184299_20	2340.JV46_23140	2.366e-50	181.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1J5ZB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS2_k127_4184299_15	1137799.GZ78_16925	4.77e-70	241.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XJIQ@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS2_k127_4184299_12	395493.BegalDRAFT_1026	1.324e-88	299.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,1S29T@1236|Gammaproteobacteria,4620G@72273|Thiotrichales	72273|Thiotrichales	U	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
CMS2_k127_4184299_9	375286.mma_3383	3.23e-100	334.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,476I6@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
CMS2_k127_4184299_14	395493.BegalDRAFT_2963	3.263e-72	250.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,463JA@72273|Thiotrichales	72273|Thiotrichales	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Peptidase_S15
CMS2_k127_4184299_22	1123401.JHYQ01000012_gene2859	3.058e-46	168.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,461G4@72273|Thiotrichales	72273|Thiotrichales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
CMS2_k127_4184299_7	472759.Nhal_0846	6.815e-107	361.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1WWXD@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
CMS2_k127_4184299_13	323261.Noc_0938	1.121e-79	271.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1WWM4@135613|Chromatiales	135613|Chromatiales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
CMS2_k127_4184299_4	2340.JV46_11270	6.451e-141	450.0	COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1J5KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3412,iSDY_1059.SDY_0027	AdoMet_dc
CMS2_k127_4184299_18	1123368.AUIS01000011_gene1183	1.561e-59	208.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_4184299_16	95619.PM1_0200440	2.509e-63	219.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Redox protein regulator of disulfide bond formation	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS2_k127_4184299_10	1056820.KB900631_gene2273	4.527e-98	324.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,2PN0Z@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	T	helix_turn_helix, cAMP Regulatory protein	crp	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,cNMP_binding
CMS2_k127_4184299_6	1168065.DOK_01194	6.729e-110	361.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1J4PJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0422	IGPS
CMS2_k127_4184299_3	519989.ECTPHS_03764	1.664e-144	467.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1WW7U@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS2_k127_4184299_2	314345.SPV1_13232	1.178e-149	484.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria	1224|Proteobacteria	EGP	drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
CMS2_k127_4184299_11	207954.MED92_16505	4.655e-98	323.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1XH6R@135619|Oceanospirillales	135619|Oceanospirillales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS2_k127_4184299_25	929556.Solca_0792	1.505e-11	67.0	COG0614@1|root,COG0614@2|Bacteria,4NPTQ@976|Bacteroidetes,1ITF5@117747|Sphingobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CMS2_k127_4184299_0	572477.Alvin_0270	2.25e-234	733.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WX6V@135613|Chromatiales	135613|Chromatiales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS2_k127_4184299_8	1049564.TevJSym_ag00460	7.902e-107	351.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	HAD-hyrolase-like	gph	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756	HAD_2
CMS2_k127_4184299_5	1485544.JQKP01000001_gene960	1.261e-133	427.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,44V7D@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS2_k127_4184299_17	396588.Tgr7_2880	2.162e-60	214.0	COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,1WZE3@135613|Chromatiales	135613|Chromatiales	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
CMS2_k127_4184299_21	697282.Mettu_0377	1.705e-48	184.0	COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria,1XF9U@135618|Methylococcales	135618|Methylococcales	C	ATP synthase	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS2_k127_4184299_1	1415778.JQMM01000001_gene2181	2.766e-216	681.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1J5DU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS2_k127_4184299_19	472759.Nhal_2237	1.412e-52	195.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,1R6C0@1224|Proteobacteria,1S4NA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
CMS2_k127_4184299_23	522306.CAP2UW1_2680	3.331e-32	131.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,2VWUS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE-2	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS2_k127_4184299_24	472759.Nhal_2239	2.504e-27	111.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS2_k127_423805_11	1163617.SCD_n01443	2.462e-12	69.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS2_k127_423805_1	1397528.Q671_16195	2.534e-135	436.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XHSS@135619|Oceanospirillales	135619|Oceanospirillales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_423805_2	1123392.AQWL01000002_gene1825	1.742e-130	423.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VHRB@28216|Betaproteobacteria,1KTII@119069|Hydrogenophilales	119069|Hydrogenophilales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_423805_8	1163617.SCD_n01447	1.615e-37	146.0	2AQ4B@1|root,31F9K@2|Bacteria,1N38C@1224|Proteobacteria,2VRH0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_423805_3	1397528.Q671_16185	1.43e-92	315.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Secretion protein	ybhG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_423805_4	1163617.SCD_n01438	1.027e-84	297.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,2VXKM@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS2_k127_423805_0	545264.KB898744_gene1989	0.0	1084.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS2_k127_423805_7	713586.KB900536_gene2444	1.436e-51	197.0	COG0845@1|root,COG0845@2|Bacteria,1RE6W@1224|Proteobacteria,1S89W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS2_k127_423805_10	292415.Tbd_1357	1.963e-13	76.0	COG3909@1|root,COG3909@2|Bacteria,1MYD4@1224|Proteobacteria,2VP8P@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
CMS2_k127_423805_5	396588.Tgr7_0301	7.784e-64	224.0	COG1309@1|root,COG1309@2|Bacteria,1ND26@1224|Proteobacteria,1S4SI@1236|Gammaproteobacteria,1X1H8@135613|Chromatiales	135613|Chromatiales	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS2_k127_423805_6	1049564.TevJSym_ae00850	1.205e-51	190.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1J6WH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS2_k127_423805_9	318167.Sfri_3533	9.383e-19	96.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,2Q8VA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS2_k127_4294979_39	1049564.TevJSym_ai00610	1.345e-06	58.0	COG3313@1|root,COG3313@2|Bacteria	2|Bacteria	S	Fe-S protein	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
CMS2_k127_4294979_12	395493.BegalDRAFT_3083	6.35e-116	381.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,1RNYE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
CMS2_k127_4294979_20	1249627.D779_1713	1.225e-85	291.0	28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,1RNYB@1236|Gammaproteobacteria,1WW5I@135613|Chromatiales	135613|Chromatiales	H	PFAM Dinitrogenase reductase ADP-ribosyltransferase	-	-	2.4.2.37	ko:K05951	-	-	-	-	ko00000,ko01000	-	-	-	DRAT
CMS2_k127_4294979_7	159087.Daro_1415	5.216e-164	519.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2VIK4@28216|Betaproteobacteria,2KUME@206389|Rhodocyclales	206389|Rhodocyclales	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
CMS2_k127_4294979_1	580332.Slit_0882	3.026e-285	880.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,2VHMG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrogenase molybdenum-iron protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
CMS2_k127_4294979_0	870187.Thini_4010	1.277e-302	932.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RMV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
CMS2_k127_4294979_32	857087.Metme_1463	8.165e-30	119.0	COG5554@1|root,COG5554@2|Bacteria,1N7DQ@1224|Proteobacteria,1SD1T@1236|Gammaproteobacteria,1XFVM@135618|Methylococcales	135618|Methylococcales	Q	NifT/FixU protein	-	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
CMS2_k127_4294979_34	272942.RCAP_rcc03284	4.769e-20	92.0	COG1145@1|root,COG1145@2|Bacteria,1PTIF@1224|Proteobacteria,2VDJ7@28211|Alphaproteobacteria,1FD3K@1060|Rhodobacter	28211|Alphaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS2_k127_4294979_23	1122201.AUAZ01000022_gene3086	1.51e-75	260.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,1S0X4@1236|Gammaproteobacteria,46BCI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor, N-terminal	nifY	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
CMS2_k127_4294979_33	377629.TERTU_1542	2.215e-20	93.0	2E4UR@1|root,32ZP4@2|Bacteria,1N83W@1224|Proteobacteria,1SEK3@1236|Gammaproteobacteria,2PQES@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4294979_40	929558.SMGD1_1479	3.664e-05	51.0	COG2703@1|root,COG2703@2|Bacteria,1N9YV@1224|Proteobacteria,42V6I@68525|delta/epsilon subdivisions,2YQMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
CMS2_k127_4294979_21	768671.ThimaDRAFT_3611	1.084e-82	283.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,1RMES@1236|Gammaproteobacteria,1WXRR@135613|Chromatiales	135613|Chromatiales	H	Transcriptional regulator, ModE family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
CMS2_k127_4294979_19	1122197.ATWI01000011_gene263	1.096e-87	297.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4675T@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	molybdenum ABC transporter, periplasmic	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS2_k127_4294979_16	1163617.SCD_n01057	5.661e-105	344.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Molybdate ABC transporter	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS2_k127_4294979_10	572477.Alvin_0885	1.317e-126	414.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1WWTJ@135613|Chromatiales	135613|Chromatiales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
CMS2_k127_4294979_14	1348657.M622_08260	1.115e-110	362.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria	1224|Proteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS2_k127_4294979_8	317025.Tcr_0435	5.852e-159	512.0	COG4591@1|root,COG4591@2|Bacteria,1RD9H@1224|Proteobacteria,1SZ4B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_4294979_3	1348657.M622_08270	4.81e-193	613.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VKX2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS2_k127_4294979_17	317025.Tcr_0433	1.529e-104	344.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,461YN@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_4294979_11	1348657.M622_08280	5.884e-124	409.0	2C2F5@1|root,32WND@2|Bacteria,1N9J7@1224|Proteobacteria,2W66E@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4294979_9	1123393.KB891316_gene1212	1.084e-136	441.0	28I2K@1|root,2ZAEK@2|Bacteria,1R9HK@1224|Proteobacteria,2VZM5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4294979_24	1485545.JQLW01000006_gene221	1.407e-73	255.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria	1224|Proteobacteria	F	Glutamine amido-transferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS2_k127_4294979_6	318167.Sfri_1812	9.607e-165	527.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
CMS2_k127_4294979_15	279714.FuraDRAFT_2967	1.337e-110	362.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria,2KR6Z@206351|Neisseriales	206351|Neisseriales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_4294979_13	472759.Nhal_2258	3.755e-114	383.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1WX2Q@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23,OEP
CMS2_k127_4294979_22	323261.Noc_0675	9.529e-78	278.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,1X2Q8@135613|Chromatiales	135613|Chromatiales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS2_k127_4294979_25	443143.GM18_0628	6.984e-70	244.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42RGE@68525|delta/epsilon subdivisions,2WNF7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07662	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_4294979_38	1238450.VIBNISOn1_400001	5.841e-07	57.0	COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria,1XWIC@135623|Vibrionales	135623|Vibrionales	NPTU	COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein	cpxP	-	-	ko:K06006	-	-	-	-	ko00000,ko03110	-	-	-	LTXXQ
CMS2_k127_4294979_5	1123392.AQWL01000003_gene469	1.629e-180	572.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,1KRKX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS2_k127_4294979_2	1122201.AUAZ01000022_gene3095	5.939e-255	793.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,1RQ8X@1236|Gammaproteobacteria,465HD@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
CMS2_k127_4294979_4	768671.ThimaDRAFT_4656	8.784e-189	600.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,1RPBI@1236|Gammaproteobacteria,1WWZJ@135613|Chromatiales	135613|Chromatiales	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
CMS2_k127_4294979_28	765911.Thivi_2738	6.485e-42	159.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,1S50W@1236|Gammaproteobacteria,1WY7T@135613|Chromatiales	135613|Chromatiales	S	PFAM Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
CMS2_k127_4294979_26	572477.Alvin_0906	1.207e-68	235.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,1S5CH@1236|Gammaproteobacteria,1WY3N@135613|Chromatiales	135613|Chromatiales	S	Nitrogen fixation protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
CMS2_k127_4294979_35	580332.Slit_0908	7.515e-20	91.0	2DQ5Y@1|root,334WI@2|Bacteria,1QWGA@1224|Proteobacteria,2VWW1@28216|Betaproteobacteria,44WJN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
CMS2_k127_4294979_31	765914.ThisiDRAFT_1853	3.198e-38	145.0	COG1143@1|root,COG1143@2|Bacteria,1N1SG@1224|Proteobacteria,1SA3T@1236|Gammaproteobacteria,1X2TB@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS2_k127_4294979_29	697282.Mettu_3350	1.005e-40	154.0	COG3411@1|root,COG3411@2|Bacteria,1N0XK@1224|Proteobacteria,1S9F8@1236|Gammaproteobacteria,1XGY5@135618|Methylococcales	135618|Methylococcales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4294979_27	118163.Ple7327_1252	4.976e-47	182.0	COG2014@1|root,COG2014@2|Bacteria,1G3R0@1117|Cyanobacteria,3VKZQ@52604|Pleurocapsales	1117|Cyanobacteria	S	Putative heavy-metal chelation	-	-	-	ko:K09138	-	-	-	-	ko00000	-	-	-	DUF364,DUF4213
CMS2_k127_4294979_18	713586.KB900536_gene1696	7.995e-103	345.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WX7A@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS2_k127_4294979_30	1167006.UWK_00342	8.018e-39	150.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,42TNE@68525|delta/epsilon subdivisions,2WQI7@28221|Deltaproteobacteria,2MKFM@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_4294979_37	1232683.ADIMK_0084	3.413e-10	61.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS2_k127_4326393_16	396588.Tgr7_0172	1.58e-14	73.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS2_k127_4326393_2	395493.BegalDRAFT_0778	9.677e-253	794.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4607X@72273|Thiotrichales	72273|Thiotrichales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS2_k127_4326393_8	396588.Tgr7_0585	5.076e-53	198.0	2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1T0F6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4326393_14	1144342.PMI40_00528	7.969e-23	106.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VSZR@28216|Betaproteobacteria,4732K@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0149)	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
CMS2_k127_4326393_18	1415779.JOMH01000001_gene2248	2.238e-05	53.0	COG5642@1|root,COG5642@2|Bacteria,1PQ5A@1224|Proteobacteria,1TAWP@1236|Gammaproteobacteria,1XBN0@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
CMS2_k127_4326393_11	305700.B447_11692	1.155e-28	123.0	2BGQ8@1|root,32AP7@2|Bacteria,1RHYY@1224|Proteobacteria,2VSYN@28216|Betaproteobacteria,2KWTW@206389|Rhodocyclales	206389|Rhodocyclales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS2_k127_4326393_5	76869.PputGB1_1323	6.616e-70	243.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,1YUYH@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
CMS2_k127_4326393_3	1121374.KB891585_gene2307	1.396e-171	547.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS2_k127_4326393_15	247633.GP2143_01875	2.211e-19	94.0	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,1SCE8@1236|Gammaproteobacteria,1J6W5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
CMS2_k127_4326393_6	580332.Slit_1216	1.409e-66	234.0	COG2020@1|root,COG2020@2|Bacteria,1PPQV@1224|Proteobacteria,2VR3S@28216|Betaproteobacteria	28216|Betaproteobacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	-
CMS2_k127_4326393_7	400682.PAC_15704163	1.151e-57	205.0	COG1495@1|root,2SDDI@2759|Eukaryota,3AE24@33154|Opisthokonta,3BWEU@33208|Metazoa	33208|Metazoa	O	Disulfide bond formation protein DsbB	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
CMS2_k127_4326393_9	349521.HCH_01554	2.457e-47	179.0	COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,1XKK5@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09912	-	-	-	-	ko00000	-	-	-	DUF2058
CMS2_k127_4326393_12	1042377.AFPJ01000030_gene446	3.061e-28	117.0	2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
CMS2_k127_4326393_4	647113.Metok_1325	4.872e-101	342.0	COG0477@1|root,arCOG00130@2157|Archaea,2XU3E@28890|Euryarchaeota,23QKI@183939|Methanococci	183939|Methanococci	G	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_4326393_10	247633.GP2143_01800	2.885e-44	167.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NnrU protein	nnrU	-	-	-	-	-	-	-	-	-	-	-	NnrU
CMS2_k127_4326393_1	518766.Rmar_0342	7.418e-262	818.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1FJVJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS2_k127_4326393_13	1123377.AUIV01000009_gene2599	7.581e-27	116.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SZKQ@1236|Gammaproteobacteria,1XCWA@135614|Xanthomonadales	135614|Xanthomonadales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_4326393_0	1049564.TevJSym_al00310	0.0	1230.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1J5CY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_4326393_17	301.JNHE01000005_gene997	6.324e-10	66.0	COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,1YCUH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	37-kD nucleoid-associated bacterial protein	ndpA	-	-	ko:K06899	-	-	-	-	ko00000,ko03036	-	-	-	NA37
CMS2_k127_4339783_0	391615.ABSJ01000036_gene976	4.743e-110	357.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1J5DE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS2_k127_4339783_9	1120953.AUBH01000019_gene3295	6.045e-05	46.0	2AXY7@1|root,31PZH@2|Bacteria,1QMNF@1224|Proteobacteria,1TJXZ@1236|Gammaproteobacteria,46C9S@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4339783_7	1111732.AZOD01000002_gene1737	1.234e-07	56.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4339783_5	1535422.ND16A_2544	4.918e-11	65.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,2Q8EN@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4339783_8	1123239.KB898630_gene2582	3.686e-06	51.0	2ED1A@1|root,336Y8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4339783_4	396588.Tgr7_2401	1.546e-11	74.0	2E02Y@1|root,32VRV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_4339783_2	1026882.MAMP_02916	1.124e-45	174.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,4610E@72273|Thiotrichales	72273|Thiotrichales	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS2_k127_4339783_1	686340.Metal_0899	9.028e-91	309.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XDR3@135618|Methylococcales	135618|Methylococcales	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS2_k127_4339783_3	83406.HDN1F_12820	7.425e-35	138.0	COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1J66J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein	uspA	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
CMS2_k127_4366907_19	177437.HRM2_33850	3.479e-05	55.0	2AHJ8@1|root,317WV@2|Bacteria,1PZDF@1224|Proteobacteria,435WU@68525|delta/epsilon subdivisions,2X0D7@28221|Deltaproteobacteria,2MP58@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4366907_14	765911.Thivi_3750	9.917e-36	141.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales	135613|Chromatiales	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
CMS2_k127_4366907_17	1163617.SCD_n02318	4.911e-08	59.0	2EA5W@1|root,334AS@2|Bacteria,1NFAR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4366907_7	472759.Nhal_2283	7.721e-97	323.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1WY1K@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM 3'(2'),5'-bisphosphate nucleotidase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS2_k127_4366907_9	396588.Tgr7_2931	2.921e-74	257.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1WXW6@135613|Chromatiales	135613|Chromatiales	L	PFAM NUDIX hydrolase	nudE	-	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS2_k127_4366907_8	1163617.SCD_n01123	5.863e-90	301.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,2VZS8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS2_k127_4366907_11	396588.Tgr7_2929	2.837e-54	196.0	COG0727@1|root,COG0727@2|Bacteria,1NXZE@1224|Proteobacteria,1SQVM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS2_k127_4366907_6	666681.M301_2516	1.31e-98	349.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,2KNH8@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS2_k127_4366907_16	207954.MED92_17384	1.417e-20	102.0	COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,1SEI1@1236|Gammaproteobacteria,1XKXH@135619|Oceanospirillales	135619|Oceanospirillales	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
CMS2_k127_4366907_5	225849.swp_1351	3.952e-111	390.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q95S@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
CMS2_k127_4366907_3	519989.ECTPHS_02801	3.242e-181	576.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales	135613|Chromatiales	L	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_4366907_10	1249627.D779_1317	1.146e-57	201.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1WY87@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS2_k127_4366907_2	187272.Mlg_0367	2.426e-232	724.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1WW22@135613|Chromatiales	135613|Chromatiales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS2_k127_4366907_0	1163617.SCD_n02100	0.0	1136.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
CMS2_k127_4366907_20	1121935.AQXX01000121_gene5526	0.0001057	49.0	2DNT8@1|root,32Z10@2|Bacteria,1PVKQ@1224|Proteobacteria,1RU3D@1236|Gammaproteobacteria,1XMEJ@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF3135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3135
CMS2_k127_4366907_15	754477.Q7C_1792	7.938e-32	124.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,461AF@72273|Thiotrichales	72273|Thiotrichales	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS2_k127_4366907_12	440512.C211_09004	2.141e-49	187.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS2_k127_4366907_13	349124.Hhal_2252	8.766e-48	181.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,1T424@1236|Gammaproteobacteria,1X2QN@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4366907_1	472759.Nhal_3892	4.17e-289	910.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS2_k127_4366907_4	472759.Nhal_3891	2.397e-152	488.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS2_k127_4375866_8	713586.KB900536_gene2986	1.035e-71	245.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1WW6E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS2_k127_4375866_9	713586.KB900536_gene2984	1.204e-66	236.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1WYD7@135613|Chromatiales	135613|Chromatiales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS2_k127_4375866_5	1038869.AXAN01000005_gene5384	1.15e-77	262.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1K11Z@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS2_k127_4375866_6	1049564.TevJSym_aa02170	5.879e-77	266.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1J5TJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
CMS2_k127_4375866_3	754476.Q7A_747	1.472e-143	470.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,46060@72273|Thiotrichales	72273|Thiotrichales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
CMS2_k127_4375866_12	1453501.JELR01000002_gene1430	0.0002592	53.0	COG3509@1|root,COG3509@2|Bacteria,1R66H@1224|Proteobacteria,1SZAS@1236|Gammaproteobacteria,466AM@72275|Alteromonadaceae	1224|Proteobacteria	Q	Esterase PHB depolymerase	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	Esterase_phd
CMS2_k127_4375866_4	1120949.KB903316_gene74	1.14e-109	373.0	COG1404@1|root,COG3506@1|root,COG1404@2|Bacteria,COG3506@2|Bacteria,2I8MD@201174|Actinobacteria,4DM2S@85008|Micromonosporales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_S8,SLH,fn3_5
CMS2_k127_4375866_11	1123518.ARWI01000001_gene1638	3.538e-31	128.0	2DQ3J@1|root,334KB@2|Bacteria,1NFUT@1224|Proteobacteria,1SH2X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4375866_10	1121921.KB898707_gene1015	6.236e-48	193.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_5,Cadherin,Cadherin_3,He_PIG,OMP_b-brl,OmpA_membrane,fn3
CMS2_k127_4375866_7	1278309.KB907099_gene2910	2.416e-76	279.0	COG2132@1|root,COG3828@1|root,COG2132@2|Bacteria,COG3828@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
CMS2_k127_4375866_2	1278309.KB907099_gene2911	8.978e-145	471.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,TAT_signal
CMS2_k127_4375866_1	1278309.KB907099_gene2912	1.307e-152	494.0	COG2132@1|root,COG2132@2|Bacteria,1R89G@1224|Proteobacteria,1S5X0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
CMS2_k127_4375866_0	1278309.KB907099_gene2913	0.0	1361.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4392940_12	177439.DP1198	1.007e-46	170.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NK7@68525|delta/epsilon subdivisions,2WKTV@28221|Deltaproteobacteria,2MMQF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,ELFV_dehydrog,ELFV_dehydrog_N
CMS2_k127_4392940_6	713586.KB900536_gene384	3.51e-111	367.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,1WXTU@135613|Chromatiales	135613|Chromatiales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_4392940_1	1123393.KB891333_gene2641	5.043e-300	938.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS2_k127_4392940_5	338969.Rfer_1702	2.408e-122	404.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,4ADVF@80864|Comamonadaceae	28216|Betaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
CMS2_k127_4392940_2	177439.DP1202	3.035e-269	839.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MHX9@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS2_k127_4392940_8	1232410.KI421424_gene1749	3.629e-73	261.0	COG0412@1|root,COG0412@2|Bacteria,1QW3K@1224|Proteobacteria,43C4E@68525|delta/epsilon subdivisions,2X7EV@28221|Deltaproteobacteria,43S1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4392940_4	697282.Mettu_4037	3.204e-190	601.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1XDX9@135618|Methylococcales	1236|Gammaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	iYL1228.KPN_02462	AdoHcyase,AdoHcyase_NAD
CMS2_k127_4392940_7	697282.Mettu_4038	3.46e-74	255.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S48C@1236|Gammaproteobacteria,1XGYF@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS2_k127_4392940_10	357804.Ping_2701	1.455e-68	239.0	COG1278@1|root,COG1544@1|root,COG1278@2|Bacteria,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,1S5AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	PFAM Cold-shock protein, DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
CMS2_k127_4392940_3	1123368.AUIS01000007_gene2809	3.259e-203	643.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,2NBT2@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CMS2_k127_4392940_11	1232410.KI421424_gene1750	2.402e-56	205.0	COG0637@1|root,COG0637@2|Bacteria,1QUMB@1224|Proteobacteria,43BM1@68525|delta/epsilon subdivisions,2X6Z7@28221|Deltaproteobacteria,43URF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	Hydrolase
CMS2_k127_4392940_9	926569.ANT_16230	8.204e-71	255.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi	200795|Chloroflexi	J	modification enzyme, MiaB family	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS2_k127_4392940_0	472759.Nhal_2787	0.0	1335.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1WXTJ@135613|Chromatiales	135613|Chromatiales	C	Belongs to the aconitase IPM isomerase family	-	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
CMS2_k127_4431974_2	378806.STAUR_5544	4.885e-28	122.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2YX8Z@29|Myxococcales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
CMS2_k127_4431974_0	1123053.AUDG01000001_gene2298	3.513e-211	671.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,1RRHJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yqiK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
CMS2_k127_4431974_1	1121396.KB892917_gene102	2.496e-54	198.0	COG1585@1|root,COG1585@2|Bacteria,1RG29@1224|Proteobacteria,42Y3F@68525|delta/epsilon subdivisions,2WUYI@28221|Deltaproteobacteria,2MN9K@213118|Desulfobacterales	28221|Deltaproteobacteria	OU	Protein of unknown function (DUF1449)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
CMS2_k127_4431974_3	713586.KB900536_gene2658	5.069e-06	52.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales	135613|Chromatiales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4462961_0	1131553.JIBI01000033_gene2333	5.479e-176	566.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VM55@28216|Betaproteobacteria	28216|Betaproteobacteria	EJ	Psort location Cytoplasmic, score 9.26	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS2_k127_4462961_2	572477.Alvin_2394	1.136e-110	368.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1WXA2@135613|Chromatiales	135613|Chromatiales	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,Response_reg
CMS2_k127_4462961_1	946483.Cenrod_1285	2.928e-161	563.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG3829@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AA9F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
CMS2_k127_4462961_3	1341151.ASZU01000006_gene2783	1.312e-53	194.0	COG4123@1|root,COG4123@2|Bacteria,1UIJU@1239|Firmicutes,4ISKM@91061|Bacilli,27C2W@186824|Thermoactinomycetaceae	91061|Bacilli	S	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
CMS2_k127_4466073_11	686340.Metal_3171	3.131e-102	343.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XE6R@135618|Methylococcales	135618|Methylococcales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS2_k127_4466073_21	1335757.SPICUR_07275	7.984e-42	162.0	COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1WZ46@135613|Chromatiales	135613|Chromatiales	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS2_k127_4466073_18	713586.KB900536_gene1890	4.397e-63	220.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1WYA9@135613|Chromatiales	135613|Chromatiales	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
CMS2_k127_4466073_23	580332.Slit_2372	1.334e-37	146.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
CMS2_k127_4466073_15	269799.Gmet_0169	3.836e-89	299.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,42UMC@68525|delta/epsilon subdivisions,2WQJQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS2_k127_4466073_13	323261.Noc_0191	9.713e-98	326.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WYU5@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS2_k127_4466073_20	589865.DaAHT2_0117	1.746e-42	162.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,42TQE@68525|delta/epsilon subdivisions,2WQIC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Outer membrane lipoprotein Slp	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
CMS2_k127_4466073_25	105559.Nwat_1207	1.506e-33	136.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1S9UB@1236|Gammaproteobacteria,1WYVZ@135613|Chromatiales	135613|Chromatiales	M	PFAM Outer membrane lipoprotein Slp	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
CMS2_k127_4466073_27	396588.Tgr7_3049	5.4e-14	76.0	COG5481@1|root,COG5481@2|Bacteria	2|Bacteria	S	small protein containing a coiled-coil domain	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
CMS2_k127_4466073_1	713586.KB900536_gene2613	5.79e-243	767.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales	135613|Chromatiales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
CMS2_k127_4466073_3	1137799.GZ78_21080	3.002e-167	535.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales	135619|Oceanospirillales	J	SAM-dependent	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS2_k127_4466073_28	420890.LCGL_0826	4.549e-10	63.0	COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,4HH71@91061|Bacilli,1YBV8@1357|Lactococcus	91061|Bacilli	H	RibD C-terminal domain	ywjB	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS2_k127_4466073_6	1523503.JPMY01000006_gene2139	3.263e-121	394.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS2_k127_4466073_7	1122221.JHVI01000023_gene428	4.467e-118	386.0	COG0207@1|root,COG0207@2|Bacteria,1WM4Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS2_k127_4466073_19	1049564.TevJSym_ao00170	9.917e-56	199.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1J69X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363	1.5.1.3	ko:K00287,ko:K18590	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020	DHFR_1
CMS2_k127_4466073_14	754476.Q7A_2662	1.77e-89	303.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,45ZVS@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_4466073_17	472759.Nhal_2746	1.635e-72	252.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WVYN@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CMS2_k127_4466073_5	1286106.MPL1_08544	2.309e-128	419.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,45ZZZ@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS2_k127_4466073_2	472759.Nhal_2748	1.174e-210	671.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
CMS2_k127_4466073_16	713586.KB900536_gene2722	8.008e-89	297.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1WY08@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
CMS2_k127_4466073_12	396588.Tgr7_2626	3.396e-98	323.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1WX8K@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_4466073_0	1049564.TevJSym_af01070	0.0	1082.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1J4VI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS2_k127_4466073_4	870187.Thini_0775	3.329e-158	505.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4606S@72273|Thiotrichales	72273|Thiotrichales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS2_k127_4466073_8	396588.Tgr7_2620	1.266e-113	367.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1WW5U@135613|Chromatiales	135613|Chromatiales	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
CMS2_k127_4466073_10	887327.HMPREF0476_1995	1.161e-102	357.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria,2KPPA@206351|Neisseriales	206351|Neisseriales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS2_k127_4466073_26	1026882.MAMP_02026	8.644e-32	135.0	COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T42I@1236|Gammaproteobacteria,460XW@72273|Thiotrichales	72273|Thiotrichales	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS2_k127_4466073_9	317025.Tcr_1743	1.95e-113	382.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1RPPS@1236|Gammaproteobacteria,46100@72273|Thiotrichales	72273|Thiotrichales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS2_k127_4466073_24	1163617.SCD_n01748	9.558e-37	156.0	COG0671@1|root,COG0671@2|Bacteria,1NAJ7@1224|Proteobacteria,2VX11@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS2_k127_4466073_22	1168067.JAGP01000001_gene435	9.347e-41	169.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,1SDDS@1236|Gammaproteobacteria,461W1@72273|Thiotrichales	72273|Thiotrichales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS2_k127_4467602_9	1034943.BN1094_00294	2.084e-74	258.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1JC5V@118969|Legionellales	118969|Legionellales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS2_k127_4467602_17	194439.CT0075	2.278e-25	108.0	COG3245@1|root,COG3245@2|Bacteria,1FE9H@1090|Chlorobi	1090|Chlorobi	C	PFAM cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_4467602_11	1049564.TevJSym_as00580	2.512e-66	232.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1J6DD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2863 Cytochrome c553	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_4467602_1	396588.Tgr7_0090	1.402e-191	620.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,1X08B@135613|Chromatiales	135613|Chromatiales	O	ResB-like family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS2_k127_4467602_2	1123401.JHYQ01000036_gene1681	8.958e-175	557.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS2_k127_4467602_16	1123368.AUIS01000005_gene371	8.009e-49	180.0	COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,1SA1H@1236|Gammaproteobacteria,2NCCT@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS2_k127_4467602_13	243233.MCA2602	1.05e-56	205.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XEWA@135618|Methylococcales	135618|Methylococcales	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
CMS2_k127_4467602_0	1026882.MAMP_00725	1.732e-278	865.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS2_k127_4467602_8	349124.Hhal_2393	1.815e-87	297.0	COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1S296@1236|Gammaproteobacteria,1X2D7@135613|Chromatiales	135613|Chromatiales	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS2_k127_4467602_4	472759.Nhal_3774	1.476e-105	351.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1WWFG@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
CMS2_k127_4467602_3	1232683.ADIMK_2146	2.362e-169	546.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,464SD@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS2_k127_4467602_18	335283.Neut_1490	3.948e-13	75.0	2DP3X@1|root,330EQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,Rick_17kDa_Anti
CMS2_k127_4467602_14	1123393.KB891328_gene668	2.397e-55	200.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2VR8H@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS2_k127_4467602_10	1132855.KB913035_gene1273	1.625e-72	247.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VT80@28216|Betaproteobacteria,2KMQP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
CMS2_k127_4467602_12	1123368.AUIS01000001_gene1884	7.332e-63	222.0	COG0607@1|root,COG0607@2|Bacteria,1P2AX@1224|Proteobacteria,1SRQD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_4467602_15	637905.SVI_0385	6.009e-55	203.0	COG0607@1|root,COG0607@2|Bacteria,1RM2N@1224|Proteobacteria,1S8IB@1236|Gammaproteobacteria,2QD6M@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_4467602_7	2340.JV46_07570	6.951e-88	294.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,1J6R4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
CMS2_k127_4467602_6	396588.Tgr7_1944	9.451e-90	298.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,1S55P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS2_k127_4467602_5	580332.Slit_0871	5.148e-91	302.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,2VQ08@28216|Betaproteobacteria,44WAQ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM cation efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
CMS2_k127_4546840_12	713586.KB900536_gene1631	6.215e-89	310.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,1T1HX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS2_k127_4546840_14	1049564.TevJSym_bd00190	5.524e-85	289.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1JBV7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulatory protein, C terminal	ompR	GO:0000156,GO:0000160,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0035556,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_4546840_16	357804.Ping_0701	3.626e-72	251.0	COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria,1S5D0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
CMS2_k127_4546840_36	1125863.JAFN01000001_gene2198	6.464e-19	92.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
CMS2_k127_4546840_0	1158146.KB907123_gene623	0.0	1178.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1WWR1@135613|Chromatiales	135613|Chromatiales	KL	DNA RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
CMS2_k127_4546840_13	1232410.KI421412_gene422	1.504e-86	292.0	COG2519@1|root,COG2519@2|Bacteria,1QU0A@1224|Proteobacteria,43BUT@68525|delta/epsilon subdivisions,2X75U@28221|Deltaproteobacteria,43UQK@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4546840_4	243231.GSU0189	2.255e-169	552.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43S90@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
CMS2_k127_4546840_5	1163408.UU9_03932	7.537e-137	448.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl,Surface_Ag_2
CMS2_k127_4546840_19	396588.Tgr7_1122	5.069e-56	201.0	COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,1SAAR@1236|Gammaproteobacteria,1X1DX@135613|Chromatiales	135613|Chromatiales	M	17 kDa outer membrane surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti
CMS2_k127_4546840_32	225937.HP15_2758	7.565e-35	140.0	2DM33@1|root,31HZ0@2|Bacteria,1RJQ4@1224|Proteobacteria,1S7SM@1236|Gammaproteobacteria,46B2T@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4546840_27	305900.GV64_11925	2.309e-45	173.0	COG4520@1|root,COG4520@2|Bacteria,1PCU5@1224|Proteobacteria,1S861@1236|Gammaproteobacteria,1XPES@135619|Oceanospirillales	135619|Oceanospirillales	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4546840_26	1121930.AQXG01000018_gene770	9.704e-46	169.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
CMS2_k127_4546840_44	314345.SPV1_00817	1.574e-08	64.0	COG3087@1|root,COG3087@2|Bacteria,1P4K5@1224|Proteobacteria	1224|Proteobacteria	D	PFAM Sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS2_k127_4546840_39	631362.Thi970DRAFT_03484	7.002e-15	81.0	2AAM4@1|root,30ZYM@2|Bacteria,1RFTG@1224|Proteobacteria,1S4UQ@1236|Gammaproteobacteria,1WYA8@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4546840_34	1168289.AJKI01000031_gene1012	6.091e-29	119.0	COG3118@1|root,COG3118@2|Bacteria,4PPAS@976|Bacteroidetes,2G14Z@200643|Bacteroidia,3XK9G@558415|Marinilabiliaceae	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CMS2_k127_4546840_43	1049564.TevJSym_bd00100	5.576e-09	63.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	bta	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin,TraF
CMS2_k127_4546840_6	1249627.D779_1874	2.293e-94	318.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1X04E@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_4546840_11	1469245.JFBG01000001_gene538	3.407e-89	301.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
CMS2_k127_4546840_24	765913.ThidrDRAFT_3655	6.826e-50	185.0	COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,1S2EF@1236|Gammaproteobacteria,1WY2H@135613|Chromatiales	135613|Chromatiales	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
CMS2_k127_4546840_37	314278.NB231_13471	1.41e-18	93.0	2E609@1|root,330PP@2|Bacteria,1NA0P@1224|Proteobacteria,1SCFG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YfaZ precursor	-	-	-	-	-	-	-	-	-	-	-	-	YfaZ
CMS2_k127_4546840_22	1163617.SCD_n02112	3.145e-52	192.0	COG3448@1|root,COG3448@2|Bacteria,1QUQ5@1224|Proteobacteria,2WGXX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS2_k127_4546840_31	1298593.TOL_1974	1.532e-36	147.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1SBVN@1236|Gammaproteobacteria,1XREE@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the bacterial histone-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
CMS2_k127_4546840_20	1056820.KB900663_gene3810	3.222e-53	190.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,2PNX1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS2_k127_4546840_9	472759.Nhal_2017	1.72e-91	310.0	COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,1S2TH@1236|Gammaproteobacteria,1WY0K@135613|Chromatiales	135613|Chromatiales	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS2_k127_4546840_41	1288826.MSNKSG1_07923	1.112e-09	67.0	COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	SH3 domain protein	ygiM	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
CMS2_k127_4546840_17	317025.Tcr_1309	3.185e-67	235.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1S6AG@1236|Gammaproteobacteria,462B4@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CMS2_k127_4546840_40	1117647.M5M_00495	4.698e-14	74.0	2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria,1J7AI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3012
CMS2_k127_4546840_25	491952.Mar181_1070	4.666e-46	168.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XK38@135619|Oceanospirillales	135619|Oceanospirillales	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
CMS2_k127_4546840_18	1042375.AFPL01000004_gene611	3.485e-66	231.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,466ZZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG2755 Lysophospholipase L1 and related esterases	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
CMS2_k127_4546840_10	1452718.JBOY01000028_gene149	6.331e-90	302.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	(ABC) transporter	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_4546840_2	1323663.AROI01000009_gene3504	9.092e-247	788.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	ybbP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS2_k127_4546840_8	1123401.JHYQ01000039_gene1553	4.766e-92	324.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,462QP@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS2_k127_4546840_29	1123368.AUIS01000009_gene2451	1.927e-38	148.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS2_k127_4546840_15	396588.Tgr7_1054	2.69e-80	276.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,1WYE7@135613|Chromatiales	135613|Chromatiales	J	Pseudouridine synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
CMS2_k127_4546840_23	1487953.JMKF01000054_gene1559	2.471e-50	198.0	COG2199@1|root,COG3706@2|Bacteria,1GI9Z@1117|Cyanobacteria,1HFDY@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
CMS2_k127_4546840_35	1121861.KB899925_gene2497	9.205e-28	117.0	COG0607@1|root,COG0607@2|Bacteria,1R2IR@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_4546840_3	472759.Nhal_0005	4.166e-182	580.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1X061@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_4546840_21	1198232.CYCME_1625	1.397e-52	194.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria,462PD@72273|Thiotrichales	72273|Thiotrichales	K	Crp-like helix-turn-helix domain	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS2_k127_4546840_33	768671.ThimaDRAFT_1683	6.061e-34	138.0	COG4828@1|root,COG4828@2|Bacteria,1NPF1@1224|Proteobacteria,1SH6F@1236|Gammaproteobacteria,1X1YB@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
CMS2_k127_4546840_30	41431.PCC8801_1357	4.817e-37	145.0	COG1246@1|root,COG1246@2|Bacteria,1G856@1117|Cyanobacteria	1117|Cyanobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
CMS2_k127_4546840_7	243365.CV_2387	1.084e-93	311.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,2KPCI@206351|Neisseriales	206351|Neisseriales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS2_k127_4546840_1	1454004.AW11_03482	6.444e-250	787.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS2_k127_4653038_25	396588.Tgr7_0332	4.935e-84	283.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales	135613|Chromatiales	GM	NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
CMS2_k127_4653038_7	396588.Tgr7_0331	3.495e-170	544.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS2_k127_4653038_40	314345.SPV1_13137	3.236e-35	138.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
CMS2_k127_4653038_26	1163617.SCD_n02189	1.548e-83	290.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2VPWB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2
CMS2_k127_4653038_35	1255043.TVNIR_1671	1.335e-45	168.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1
CMS2_k127_4653038_37	631362.Thi970DRAFT_04319	4.422e-39	147.0	2CDMX@1|root,32S1K@2|Bacteria,1N1I8@1224|Proteobacteria,1S9N4@1236|Gammaproteobacteria,1WYR4@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4653038_38	472759.Nhal_0257	6.768e-39	151.0	COG1310@1|root,COG1310@2|Bacteria,1RJSM@1224|Proteobacteria,1S86M@1236|Gammaproteobacteria,1X21I@135613|Chromatiales	135613|Chromatiales	S	SMART Mov34 MPN PAD-1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
CMS2_k127_4653038_20	1232683.ADIMK_1068	9.872e-102	337.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	iECIAI1_1343.ECIAI1_0865,iECW_1372.ECW_m0884,iEKO11_1354.EKO11_3059,iETEC_1333.ETEC_0893,iEcE24377_1341.EcE24377A_0897,iEcSMS35_1347.EcSMS35_0851,iWFL_1372.ECW_m0884	ThiF
CMS2_k127_4653038_39	1049564.TevJSym_as00740	2.452e-35	138.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,1S5H3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4653038_24	1123400.KB904780_gene1765	1.768e-88	301.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,460FJ@72273|Thiotrichales	72273|Thiotrichales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS2_k127_4653038_8	870187.Thini_1102	4.627e-169	537.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS2_k127_4653038_9	1249627.D779_0933	1.355e-167	537.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS2_k127_4653038_16	323261.Noc_0511	2.168e-130	436.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales	135613|Chromatiales	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS2_k127_4653038_36	395493.BegalDRAFT_1716	2.293e-43	166.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,4617Y@72273|Thiotrichales	72273|Thiotrichales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
CMS2_k127_4653038_18	105559.Nwat_2577	5.771e-109	359.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1WX6F@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS2_k127_4653038_44	1387197.AWGA01000023_gene1079	5.189e-07	53.0	2EFWG@1|root,339NR@2|Bacteria,1NIWH@1224|Proteobacteria,1SHRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4653038_10	765914.ThisiDRAFT_0700	6.737e-155	494.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales	135613|Chromatiales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS2_k127_4653038_31	349521.HCH_01725	1.055e-71	249.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1XJNP@135619|Oceanospirillales	135619|Oceanospirillales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS2_k127_4653038_30	1168065.DOK_14424	4.736e-77	262.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1J5S9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019538,GO:0030163,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0052689,GO:0071704,GO:0140098,GO:0140101,GO:1901564,GO:1901565,GO:1901575	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS2_k127_4653038_4	1123517.JOMR01000001_gene1638	3.634e-188	592.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,45ZRA@72273|Thiotrichales	72273|Thiotrichales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS2_k127_4653038_13	472759.Nhal_1648	5.939e-146	471.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,1T05M@1236|Gammaproteobacteria,1WXY2@135613|Chromatiales	135613|Chromatiales	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS2_k127_4653038_17	870187.Thini_0745	2.161e-115	404.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462CG@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM
CMS2_k127_4653038_33	1283300.ATXB01000002_gene2631	3.526e-59	210.0	COG1814@1|root,COG1814@2|Bacteria,1RBQN@1224|Proteobacteria,1S2ZU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4653038_43	2340.JV46_07100	4.616e-20	96.0	COG1888@1|root,COG1888@2|Bacteria,1N92Y@1224|Proteobacteria,1SD5W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized ArCR, COG1888	-	-	-	ko:K09732	-	-	-	-	ko00000	-	-	-	DUF211
CMS2_k127_4653038_15	472759.Nhal_3151	1.161e-135	451.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WXFD@135613|Chromatiales	135613|Chromatiales	P	PFAM Cation	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS2_k127_4653038_23	472759.Nhal_3150	2.619e-97	322.0	COG0569@1|root,COG0569@2|Bacteria,1RDDX@1224|Proteobacteria,1S3ZR@1236|Gammaproteobacteria,1WY9A@135613|Chromatiales	135613|Chromatiales	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS2_k127_4653038_22	713586.KB900536_gene1600	5.697e-101	338.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1WWKK@135613|Chromatiales	135613|Chromatiales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS2_k127_4653038_1	391615.ABSJ01000045_gene2054	5.838e-244	761.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1J4ZC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS2_k127_4653038_0	754476.Q7A_2838	2.178e-244	761.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS2_k127_4653038_41	911239.CF149_09057	1.784e-33	131.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CMS2_k127_4653038_6	595494.Tola_0253	2.964e-180	569.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1Y3IZ@135624|Aeromonadales	135624|Aeromonadales	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS2_k127_4653038_28	765912.Thimo_2783	6.68e-80	276.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1WWKS@135613|Chromatiales	135613|Chromatiales	M	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS2_k127_4653038_34	395493.BegalDRAFT_1661	5.613e-48	178.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,461A7@72273|Thiotrichales	72273|Thiotrichales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
CMS2_k127_4653038_2	1049564.TevJSym_ao00720	1.114e-218	694.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1J4EU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
CMS2_k127_4653038_12	87626.PTD2_16122	2.549e-146	471.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,2Q05R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS2_k127_4653038_21	697282.Mettu_1395	2.885e-101	345.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1XDZY@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM Lytic murein transglycosylase B	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
CMS2_k127_4653038_29	1026882.MAMP_00706	1.07e-79	274.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,4610F@72273|Thiotrichales	72273|Thiotrichales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CMS2_k127_4653038_14	1049564.TevJSym_ao00680	1.415e-142	462.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1J4UD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S11 family	dacA	GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664	PBP5_C,Peptidase_S11
CMS2_k127_4653038_19	323261.Noc_2631	8.341e-107	353.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CMS2_k127_4653038_42	1049564.TevJSym_ao00670	3.875e-26	109.0	COG2921@1|root,COG2921@2|Bacteria,1PJDT@1224|Proteobacteria,1SXYR@1236|Gammaproteobacteria,1J7A1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0250 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
CMS2_k127_4653038_27	1452718.JBOY01000087_gene2744	1.084e-81	278.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718	BPL_LplA_LipB
CMS2_k127_4653038_11	1266908.AQPB01000037_gene444	8.956e-147	471.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS2_k127_4653038_3	82654.Pse7367_3306	2.955e-197	629.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1GQI2@1117|Cyanobacteria	1117|Cyanobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
CMS2_k127_4653038_32	395493.BegalDRAFT_1387	2.741e-65	229.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,4611P@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
CMS2_k127_4653038_5	1278309.KB907099_gene2634	6.767e-181	575.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XHP0@135619|Oceanospirillales	135619|Oceanospirillales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS2_k127_4664233_3	1122134.KB893651_gene2415	6.877e-55	193.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XKBF@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the P(II) protein family	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS2_k127_4664233_2	1123368.AUIS01000001_gene1943	8.823e-68	235.0	COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,1RMRT@1236|Gammaproteobacteria,2NDDJ@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_4664233_1	395493.BegalDRAFT_3345	3.046e-80	276.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,460GM@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS2_k127_4664233_0	42565.FP66_10245	8.958e-129	419.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XHHX@135619|Oceanospirillales	135619|Oceanospirillales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_4695186_28	1396858.Q666_15920	3.705e-09	65.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465M4@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	COG0840 Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
CMS2_k127_4695186_13	1149133.ppKF707_4016	2.908e-81	277.0	2C7BE@1|root,32RIT@2|Bacteria,1R3BT@1224|Proteobacteria,1T668@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
CMS2_k127_4695186_14	314230.DSM3645_06659	1.75e-78	277.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
CMS2_k127_4695186_1	1158182.KB905021_gene445	2.615e-264	863.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS2_k127_4695186_3	697282.Mettu_3164	1.038e-158	507.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XE8K@135618|Methylococcales	135618|Methylococcales	T	SMART Signal transduction response regulator, receiver region	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
CMS2_k127_4695186_2	1232683.ADIMK_3774	3.324e-202	647.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,464D8@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	xpsE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS2_k127_4695186_10	713586.KB900536_gene2469	3.043e-101	343.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WWYV@135613|Chromatiales	135613|Chromatiales	NU	Type II secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS2_k127_4695186_17	472759.Nhal_0441	1.008e-57	205.0	COG4968@1|root,COG4968@2|Bacteria,1QW3U@1224|Proteobacteria,1T2RU@1236|Gammaproteobacteria,1X2NZ@135613|Chromatiales	135613|Chromatiales	U	PFAM type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS2_k127_4695186_21	1255043.TVNIR_1921	1.078e-26	116.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1WY85@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein H	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CMS2_k127_4695186_27	1123377.AUIV01000012_gene768	3.467e-09	63.0	COG4967@1|root,COG4967@2|Bacteria,1QWTI@1224|Proteobacteria,1T5EA@1236|Gammaproteobacteria,1XDCG@135614|Xanthomonadales	135614|Xanthomonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS2_k127_4695186_23	323261.Noc_0756	1.231e-22	107.0	COG2165@1|root,COG2165@2|Bacteria,1NH1V@1224|Proteobacteria,1SEYM@1236|Gammaproteobacteria,1X28S@135613|Chromatiales	135613|Chromatiales	U	Pfam:N_methyl_2	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS2_k127_4695186_19	472759.Nhal_3652	1.031e-38	157.0	COG3156@1|root,COG3156@2|Bacteria,1RJRE@1224|Proteobacteria,1S6CB@1236|Gammaproteobacteria,1WW8Y@135613|Chromatiales	135613|Chromatiales	U	PFAM General secretion pathway protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS2_k127_4695186_30	1279015.KB908467_gene489	0.0002032	51.0	2ECF9@1|root,336DH@2|Bacteria,1N9HW@1224|Proteobacteria,1SFUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
CMS2_k127_4695186_4	745411.B3C1_05897	1.388e-158	525.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4XH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	General secretion pathway protein D	xpsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS2_k127_4695186_7	1249627.D779_3239	4.221e-127	426.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WWX7@135613|Chromatiales	135613|Chromatiales	U	Type II secretory pathway component ExeA	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
CMS2_k127_4695186_26	686340.Metal_3977	2.353e-09	68.0	2DRAW@1|root,33B0D@2|Bacteria,1QVQG@1224|Proteobacteria,1T53F@1236|Gammaproteobacteria,1XFJG@135618|Methylococcales	135618|Methylococcales	S	Type II secretion system protein B	-	-	-	ko:K02451	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	T2SSB
CMS2_k127_4695186_11	1278309.KB907099_gene2914	2.444e-93	327.0	COG2010@1|root,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,1T01Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
CMS2_k127_4695186_18	1278309.KB907099_gene2915	8.67e-50	185.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,1SZFZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS2_k127_4695186_20	323261.Noc_0758	1.793e-28	128.0	COG3166@1|root,COG4972@1|root,COG3166@2|Bacteria,COG4972@2|Bacteria,1RJTG@1224|Proteobacteria,1S6RT@1236|Gammaproteobacteria,1WXKF@135613|Chromatiales	135613|Chromatiales	NU	fimbrial assembly	-	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PilM_2,PilN
CMS2_k127_4695186_25	243233.MCA1122	6.539e-16	85.0	2DKUH@1|root,30CV1@2|Bacteria,1NCRM@1224|Proteobacteria,1SBMH@1236|Gammaproteobacteria,1XGYH@135618|Methylococcales	135618|Methylococcales	S	Type II secretion system (T2SS), protein M subtype b	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM_b
CMS2_k127_4695186_15	580332.Slit_1820	5.505e-74	274.0	COG3283@1|root,COG4191@1|root,COG4585@1|root,COG3283@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,1PM1X@1224|Proteobacteria,2W8ZV@28216|Betaproteobacteria,44WJK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
CMS2_k127_4695186_16	335543.Sfum_1664	7.618e-73	252.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42RQX@68525|delta/epsilon subdivisions,2WNM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS2_k127_4695186_22	580332.Slit_1819	9.953e-23	102.0	COG2197@1|root,COG2197@2|Bacteria,1NDB6@1224|Proteobacteria,2WF3F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS2_k127_4695186_0	1278309.KB907099_gene2913	0.0	1570.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4695186_6	1278309.KB907099_gene2912	5.113e-144	468.0	COG2132@1|root,COG2132@2|Bacteria,1R89G@1224|Proteobacteria,1S5X0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
CMS2_k127_4695186_5	1278309.KB907099_gene2911	2.485e-153	495.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,TAT_signal
CMS2_k127_4695186_12	1278309.KB907099_gene2910	6.622e-91	323.0	COG2132@1|root,COG3828@1|root,COG2132@2|Bacteria,COG3828@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
CMS2_k127_4695186_24	1535422.ND16A_1813	2.948e-22	102.0	2DQ3J@1|root,334KB@2|Bacteria,1NFUT@1224|Proteobacteria,1SH2X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4695186_8	1278309.KB907099_gene2909	1.31e-103	362.0	COG1404@1|root,COG3828@1|root,COG1404@2|Bacteria,COG3828@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XKSQ@135619|Oceanospirillales	135619|Oceanospirillales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_S8
CMS2_k127_4695186_29	1286632.P278_11950	7.18e-05	56.0	COG2885@1|root,COG2885@2|Bacteria,4P2MX@976|Bacteroidetes,1I8MG@117743|Flavobacteriia	976|Bacteroidetes	M	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS2_k127_4695186_9	326298.Suden_0279	2.518e-101	336.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,42PHJ@68525|delta/epsilon subdivisions,2YNKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS2_k127_4714333_36	392500.Swoo_4128	4.301e-44	175.0	2DM0S@1|root,317K8@2|Bacteria,1RM4S@1224|Proteobacteria,1S7UJ@1236|Gammaproteobacteria,2QDQJ@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4714333_41	1278309.KB907106_gene1250	4.285e-18	93.0	2DPAE@1|root,33186@2|Bacteria,1N83S@1224|Proteobacteria,1SCA3@1236|Gammaproteobacteria,1XQQA@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4714333_43	1118235.CAJH01000004_gene230	1.309e-08	63.0	2ATC8@1|root,31IVA@2|Bacteria,1QGIV@1224|Proteobacteria,1TDYV@1236|Gammaproteobacteria,1XB7J@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4714333_20	338966.Ppro_2172	4.09e-134	441.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q6R@68525|delta/epsilon subdivisions,2WJN4@28221|Deltaproteobacteria,43TK0@69541|Desulfuromonadales	1224|Proteobacteria	T	Domains REC, sigma54 interaction, HTH8	zraR	-	-	ko:K20919	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
CMS2_k127_4714333_31	1116472.MGMO_47c00080	3.438e-70	246.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,1XEJB@135618|Methylococcales	135618|Methylococcales	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
CMS2_k127_4714333_15	582744.Msip34_1491	1.25e-157	509.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,2KM89@206350|Nitrosomonadales	206350|Nitrosomonadales	EH	Anthranilate synthase component I	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS2_k127_4714333_34	391615.ABSJ01000059_gene2177	6.391e-58	202.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1J6ER@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	VL23_01195	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS2_k127_4714333_37	1216007.AOPM01000008_gene1369	3.241e-43	160.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,2Q2R7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS2_k127_4714333_5	1049564.TevJSym_ad00120	3.471e-303	948.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1J4MP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_2160,iPC815.YPO2428	B3_4,B5,FDX-ACB,tRNA_bind
CMS2_k127_4714333_14	2340.JV46_19330	3.445e-166	527.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1J559@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
CMS2_k127_4714333_35	1286106.MPL1_13083	3.242e-54	192.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,460T7@72273|Thiotrichales	72273|Thiotrichales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS2_k127_4714333_40	1121878.AUGL01000006_gene664	1.733e-19	89.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS2_k127_4714333_30	1499686.BN1079_00698	9.96e-73	248.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS2_k127_4714333_2	1026882.MAMP_02699	0.0	1053.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,45ZTX@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS2_k127_4714333_32	1219077.VAZ01S_073_00330	5.694e-64	229.0	COG2207@1|root,COG2207@2|Bacteria,1N70D@1224|Proteobacteria,1S0HI@1236|Gammaproteobacteria,1XXJ7@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS2_k127_4714333_23	1219077.VAZ01S_073_00320	1.857e-104	351.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1XSSM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4714333_28	1219077.VAZ01S_073_00310	3.701e-86	292.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XVD7@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein-sorting protein	VP1287	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS2_k127_4714333_6	1219077.VAZ01S_073_00300	6.875e-260	822.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XUBX@135623|Vibrionales	135623|Vibrionales	S	of the RND superfamily	VP1286	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS2_k127_4714333_22	1219077.VAZ01S_073_00290	1.779e-125	412.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,1SXGF@1236|Gammaproteobacteria,1Y1AV@135623|Vibrionales	135623|Vibrionales	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
CMS2_k127_4714333_18	163908.KB235896_gene269	3.282e-143	473.0	COG0318@1|root,COG0318@2|Bacteria,1G4CE@1117|Cyanobacteria,1HJ2S@1161|Nostocales	1117|Cyanobacteria	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
CMS2_k127_4714333_19	1219077.VAZ01S_073_00260	1.996e-140	457.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XSAE@135623|Vibrionales	1236|Gammaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS2_k127_4714333_38	1219077.VAZ01S_073_00250	3.891e-40	151.0	COG0822@1|root,COG0822@2|Bacteria,1NDU5@1224|Proteobacteria,1SF71@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS2_k127_4714333_11	1219077.VAZ01S_073_00240	8.503e-187	589.0	COG1541@1|root,COG1541@2|Bacteria,1NR5G@1224|Proteobacteria,1S1JA@1236|Gammaproteobacteria,1XUTW@135623|Vibrionales	1224|Proteobacteria	H	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
CMS2_k127_4714333_24	1049564.TevJSym_bb00080	1.91e-104	344.0	COG1152@1|root,COG1152@2|Bacteria,1R9TR@1224|Proteobacteria	1224|Proteobacteria	C	2Fe-2S iron-sulfur cluster binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_4,Fer4_10,Fer4_9
CMS2_k127_4714333_7	1049564.TevJSym_bb00070	8.633e-258	803.0	COG0029@1|root,COG0029@2|Bacteria,1QY0Z@1224|Proteobacteria	1224|Proteobacteria	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
CMS2_k127_4714333_10	1049564.TevJSym_bb00060	1.045e-199	628.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1J4GA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF2	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS2_k127_4714333_3	1049564.TevJSym_bb00050	1.729e-313	972.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS2_k127_4714333_13	1049564.TevJSym_bb00040	4.127e-178	561.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS2_k127_4714333_4	1049564.TevJSym_bb00030	2.212e-309	968.0	COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CMS2_k127_4714333_17	1049564.TevJSym_bb00010	1.646e-143	459.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
CMS2_k127_4714333_0	1049564.TevJSym_aq00810	0.0	1157.0	COG0674@1|root,COG1013@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	forE	-	1.2.7.1	ko:K00171,ko:K00172,ko:K02573,ko:K03737,ko:K13795,ko:K18930	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,Fer4,Fer4_4,Fer4_6,Fer4_9,Nitroreductase,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS2_k127_4714333_9	1049564.TevJSym_aq00710	6.466e-221	691.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
CMS2_k127_4714333_16	1049564.TevJSym_aq00700	4.626e-154	493.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS2_k127_4714333_29	1049564.TevJSym_aq00690	1.617e-73	258.0	COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
CMS2_k127_4714333_26	1049564.TevJSym_aq00680	2.368e-98	327.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfE2	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_4714333_25	1049564.TevJSym_aq00670	2.793e-102	335.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS2_k127_4714333_21	1049564.TevJSym_bb00090	1.707e-131	425.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1J4DY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006099,GO:0006101,GO:0006108,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009060,GO:0009061,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019898,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045333,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iEcolC_1368.EcolC_0470	Ldh_1_C,Ldh_1_N
CMS2_k127_4714333_27	395493.BegalDRAFT_1652	7.983e-87	319.0	COG2114@1|root,COG2114@2|Bacteria,1NQPW@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4714333_8	156889.Mmc1_3238	1.257e-251	788.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2TT46@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
CMS2_k127_4714333_1	1049564.TevJSym_bs00060	0.0	1059.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1J517@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS2_k127_4714333_12	754477.Q7C_362	3.906e-186	588.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,45ZUP@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase	aspC2	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS2_k127_4714333_39	1283300.ATXB01000001_gene78	2.329e-35	142.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1XFKE@135618|Methylococcales	135618|Methylococcales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
CMS2_k127_4714333_33	279714.FuraDRAFT_2392	9.399e-64	229.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2VI7W@28216|Betaproteobacteria,2KSDN@206351|Neisseriales	206351|Neisseriales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS2_k127_4723654_9	1163617.SCD_n02319	5.02e-32	130.0	2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,2VX7W@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4723654_10	156889.Mmc1_2003	7.214e-28	121.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS2_k127_4723654_6	1163617.SCD_n02349	2.246e-48	181.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,1RHTS@1224|Proteobacteria,2VTRR@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Thioredoxin_3
CMS2_k127_4723654_11	713587.THITH_06490	5.491e-25	108.0	2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,1S9XM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4723654_7	1294143.H681_17850	7.56e-47	173.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit1	-	-	-	-	-	-	-	-	-	-	-	HIT
CMS2_k127_4723654_2	314345.SPV1_04178	1.257e-102	342.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria	1224|Proteobacteria	K	Esterase of the alpha-beta hydrolase superfamily	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS2_k127_4723654_3	1380394.JADL01000005_gene5463	1.053e-96	324.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2JPGN@204441|Rhodospirillales	204441|Rhodospirillales	S	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
CMS2_k127_4723654_4	696747.NIES39_O05150	2.602e-84	295.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,1G7CP@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS2_k127_4723654_8	1110502.TMO_1165	1.236e-41	159.0	COG1695@1|root,COG1695@2|Bacteria,1N33P@1224|Proteobacteria,2VER5@28211|Alphaproteobacteria,2JYHP@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS2_k127_4723654_5	713586.KB900536_gene2614	7.117e-74	261.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,1WYGI@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_4723654_0	395493.BegalDRAFT_2091	0.0	1224.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
CMS2_k127_4723654_1	1485544.JQKP01000004_gene505	2.269e-154	492.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
CMS2_k127_4778477_0	1049564.TevJSym_aa00670	0.0	1169.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1J4ES@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS2_k127_4778477_2	1121935.AQXX01000141_gene2034	5.139e-57	202.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XK4C@135619|Oceanospirillales	135619|Oceanospirillales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS2_k127_4778477_3	396588.Tgr7_3218	9.305e-40	154.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans	fkpB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS2_k127_4778477_1	1452718.JBOY01000007_gene3390	1.126e-140	452.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024	LYTB
CMS2_k127_4807065_8	1049564.TevJSym_an00410	4.007e-174	547.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1J4RR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990	Transket_pyr,Transketolase_C,Transketolase_N
CMS2_k127_4807065_2	870187.Thini_2563	3.858e-204	641.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS2_k127_4807065_1	1485545.JQLW01000005_gene1121	3.865e-255	790.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria	1224|Proteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS2_k127_4807065_14	187272.Mlg_2264	1.332e-122	398.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1WW0T@135613|Chromatiales	135613|Chromatiales	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS2_k127_4807065_22	765910.MARPU_16260	1.861e-71	248.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1WXDF@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS2_k127_4807065_32	713586.KB900536_gene2086	1.67e-41	161.0	COG2863@1|root,COG2863@2|Bacteria,1RC1Y@1224|Proteobacteria,1S9J7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2863 Cytochrome c553	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_4807065_37	743720.Psefu_0327	1.67e-16	86.0	COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1YYC2@136845|Pseudomonas putida group	1236|Gammaproteobacteria	NT	CheW domain protein	chpC	-	-	ko:K06598	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS2_k127_4807065_0	1136138.JH604624_gene3943	7.304e-298	986.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
CMS2_k127_4807065_6	1207076.ALAT01000030_gene134	3.168e-183	595.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Z20M@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NT	chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
CMS2_k127_4807065_31	1397527.Q670_03905	1.454e-41	159.0	COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1XKR5@135619|Oceanospirillales	135619|Oceanospirillales	NT	Chemotaxis signal transduction protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
CMS2_k127_4807065_28	765914.ThisiDRAFT_0026	1.273e-50	182.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYJQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
CMS2_k127_4807065_26	743721.Psesu_2399	2.552e-63	220.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1X6HP@135614|Xanthomonadales	135614|Xanthomonadales	KT	response regulator	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
CMS2_k127_4807065_12	1049564.TevJSym_bn00070	2.052e-140	453.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1J4CV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_3410,iECP_1309.ECP_2941	GSH-S_ATP,GSH-S_N
CMS2_k127_4807065_24	1500890.JQNL01000001_gene943	1.172e-65	234.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1X3C8@135614|Xanthomonadales	135614|Xanthomonadales	M	tonb protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS2_k127_4807065_23	768671.ThimaDRAFT_3038	2.458e-66	231.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1WX8T@135613|Chromatiales	135613|Chromatiales	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS2_k127_4807065_33	1123519.PSJM300_01640	2.061e-41	156.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1Z2RK@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS2_k127_4807065_25	396588.Tgr7_2912	1.505e-64	227.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1WXPI@135613|Chromatiales	135613|Chromatiales	F	phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS2_k127_4807065_11	1286106.MPL1_00817	2.461e-153	490.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,4600A@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS2_k127_4807065_10	472759.Nhal_0208	5.859e-167	536.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1WVVC@135613|Chromatiales	135613|Chromatiales	F	TIGRFAM dihydroorotase, multifunctional complex type	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_4807065_13	713586.KB900536_gene1705	3.135e-129	419.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria,1X286@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase FAD-binding domain	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
CMS2_k127_4807065_9	118005.AWNK01000007_gene578	1.122e-172	548.0	COG5008@1|root,COG5008@2|Bacteria	2|Bacteria	NU	twitching motility protein	pilU	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS2_k127_4807065_5	396588.Tgr7_2918	5.012e-184	579.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS2_k127_4807065_19	342113.DM82_2518	1.181e-87	295.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1JZTS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS2_k127_4807065_17	396588.Tgr7_2920	1.721e-100	334.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1WWVS@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS2_k127_4807065_29	1049564.TevJSym_am00180	7.667e-45	169.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1J6HX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CMS2_k127_4807065_34	1278309.KB907100_gene2056	7.239e-32	126.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1XMH4@135619|Oceanospirillales	135619|Oceanospirillales	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS2_k127_4807065_3	1049564.TevJSym_am00160	9.321e-201	644.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,1J9QI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CMS2_k127_4807065_4	395493.BegalDRAFT_1624	3.39e-195	613.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,45ZWM@72273|Thiotrichales	72273|Thiotrichales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS2_k127_4807065_20	187272.Mlg_0337	9.774e-85	284.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,1X0N9@135613|Chromatiales	135613|Chromatiales	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
CMS2_k127_4807065_36	380703.AHA_3660	1.928e-27	117.0	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1Y5W4@135624|Aeromonadales	135624|Aeromonadales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
CMS2_k127_4807065_21	555778.Hneap_0282	2.862e-79	273.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WXWD@135613|Chromatiales	135613|Chromatiales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CMS2_k127_4807065_7	765912.Thimo_3101	1.844e-176	561.0	COG2807@1|root,COG2807@2|Bacteria,1QW3Y@1224|Proteobacteria,1T2RW@1236|Gammaproteobacteria,1X2P1@135613|Chromatiales	135613|Chromatiales	P	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CMS2_k127_4807065_27	713586.KB900536_gene2144	3.377e-63	229.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MP	COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS2_k127_4807065_30	228410.NE2385	1.289e-42	167.0	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,2WB3Z@28216|Betaproteobacteria,37293@32003|Nitrosomonadales	28216|Betaproteobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SNase
CMS2_k127_4807065_15	243233.MCA0321	1.018e-111	366.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XEVR@135618|Methylococcales	135618|Methylococcales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS2_k127_4807065_18	207954.MED92_05099	2.036e-93	310.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS2_k127_4807065_38	1163617.SCD_n02079	1.142e-15	80.0	2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria,2W5JW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_4807065_35	296591.Bpro_0071	1.438e-30	123.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,4AF7Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS2_k127_4807065_16	472759.Nhal_3799	1.216e-110	361.0	COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_4897302_2	1255043.TVNIR_1634	4.494e-252	798.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CK	Regulator of nitric oxide reductase transcription	nosR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4,Fer4_5
CMS2_k127_4897302_1	930169.B5T_04283	8.277e-308	952.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria,1XIUQ@135619|Oceanospirillales	135619|Oceanospirillales	C	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS2_k127_4897302_3	1278309.KB907102_gene206	4.599e-141	460.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria,1XJ1Q@135619|Oceanospirillales	135619|Oceanospirillales	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
CMS2_k127_4897302_6	1255043.TVNIR_1636	5.186e-102	342.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RY6M@1236|Gammaproteobacteria,1X2CF@135613|Chromatiales	135613|Chromatiales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
CMS2_k127_4897302_7	713587.THITH_08430	1.969e-98	330.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria,1X1TK@135613|Chromatiales	135613|Chromatiales	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
CMS2_k127_4897302_10	1278309.KB907102_gene209	2.136e-49	184.0	COG4314@1|root,COG4314@2|Bacteria,1RCDR@1224|Proteobacteria,1S7G3@1236|Gammaproteobacteria,1XRNX@135619|Oceanospirillales	135619|Oceanospirillales	C	NosL	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS2_k127_4897302_11	1158146.KB907124_gene2191	2.378e-44	164.0	COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,1SE6E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,DrsE_2
CMS2_k127_4897302_4	365044.Pnap_3569	7.189e-129	423.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,4AAT8@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CMS2_k127_4897302_0	323261.Noc_2717	0.0	1383.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria,1WVZE@135613|Chromatiales	135613|Chromatiales	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
CMS2_k127_4897302_5	1117318.PRUB_19032	4.179e-118	384.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,2Q1RV@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	peroxiredoxin glutaredoxin	VY92_02980	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Glutaredoxin,Redoxin
CMS2_k127_4897302_8	1202962.KB907169_gene2474	2.806e-86	294.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	oxyR	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS2_k127_4897302_9	228410.NE0466	2.665e-74	255.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria,372CT@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Protein of unknown function (DUF3417)	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS2_k127_4945346_17	1469613.JT55_18275	0.0007529	46.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	nrtA	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
CMS2_k127_4945346_1	1453503.AU05_08420	1.151e-223	711.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1YJ3H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K11914	-	-	-	-	ko00000,ko02044,ko03000	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
CMS2_k127_4945346_14	1123514.KB905899_gene1779	1.66e-57	208.0	COG1522@1|root,COG1522@2|Bacteria,1RG35@1224|Proteobacteria,1S484@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AsnC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS2_k127_4945346_3	555778.Hneap_0832	1.298e-188	594.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales	135613|Chromatiales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
CMS2_k127_4945346_15	572480.Arnit_0201	4.149e-57	204.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,42SCS@68525|delta/epsilon subdivisions,2YPIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS2_k127_4945346_2	555778.Hneap_0830	1.817e-208	657.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1WWHM@135613|Chromatiales	135613|Chromatiales	Q	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS2_k127_4945346_4	626887.J057_11076	3.112e-171	554.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,46656@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Gamma-glutamyltransferase	ggt1	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS2_k127_4945346_12	944547.ABLL_1025	1.704e-97	327.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2YNYS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS2_k127_4945346_16	1121921.KB898707_gene1039	8.182e-29	120.0	2CEW9@1|root,2ZAHY@2|Bacteria,1R5J3@1224|Proteobacteria,1S1BX@1236|Gammaproteobacteria,2PN5R@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
CMS2_k127_4945346_0	497964.CfE428DRAFT_6515	1.741e-242	809.0	COG0457@1|root,COG0457@2|Bacteria,46UKC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	FAT,Peptidase_C39_2
CMS2_k127_4945346_8	558884.JRGM01000150_gene3538	4.013e-130	426.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1Y3J9@135624|Aeromonadales	135624|Aeromonadales	P	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_8
CMS2_k127_4945346_5	396588.Tgr7_1263	7.475e-164	523.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1WWRC@135613|Chromatiales	135613|Chromatiales	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072,ko:K11076	ko02010,map02010	M00299,M00300	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1,3.A.1.11.2	-	-	ABC_tran,TOBE_2
CMS2_k127_4945346_9	1238182.C882_2562	1.083e-128	420.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,2JQTE@204441|Rhodospirillales	204441|Rhodospirillales	E	Putrescine transport system permease	potH	-	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
CMS2_k127_4945346_10	396588.Tgr7_1261	1.557e-118	396.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1WWBF@135613|Chromatiales	135613|Chromatiales	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11070,ko:K11074	ko02010,map02010	M00299,M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1,3.A.1.11.2	-	-	BPD_transp_1
CMS2_k127_4945346_7	1198232.CYCME_0490	2.823e-146	476.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,1RZ3M@1236|Gammaproteobacteria,460AN@72273|Thiotrichales	72273|Thiotrichales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CMS2_k127_4945346_11	1123392.AQWL01000006_gene717	3.811e-104	347.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,2WA3C@28216|Betaproteobacteria,1KRW5@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
CMS2_k127_4945346_13	666681.M301_1213	8.536e-80	274.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-3 protein	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
CMS2_k127_4945346_6	395493.BegalDRAFT_3524	9.827e-152	484.0	COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,460BF@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS2_k127_5027402_13	1452718.JBOY01000023_gene331	5.095e-17	81.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS2_k127_5027402_4	2340.JV46_11310	4.129e-102	340.0	COG1073@1|root,COG1073@2|Bacteria,1R76C@1224|Proteobacteria,1RR34@1236|Gammaproteobacteria,1J69T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS2_k127_5027402_6	1049564.TevJSym_ae00640	8.834e-97	321.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,1S2D9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
CMS2_k127_5027402_1	1049564.TevJSym_ae00650	1.286e-140	451.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS2_k127_5027402_3	2340.JV46_02960	6.653e-135	437.0	COG0398@1|root,COG0607@1|root,COG0398@2|Bacteria,COG0607@2|Bacteria,1MVF3@1224|Proteobacteria,1RSK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	SNARE associated Golgi protein	ydjX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
CMS2_k127_5027402_2	314345.SPV1_03473	6.246e-137	442.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria	1224|Proteobacteria	T	radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
CMS2_k127_5027402_9	2340.JV46_02920	2.103e-55	201.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,1S971@1236|Gammaproteobacteria,1J6Q2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS2_k127_5027402_12	2340.JV46_02910	1.993e-26	109.0	2EIMJ@1|root,33CCU@2|Bacteria,1NMXZ@1224|Proteobacteria,1SHQA@1236|Gammaproteobacteria,1J797@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5027402_5	765913.ThidrDRAFT_3335	2.592e-99	330.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1WW2T@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
CMS2_k127_5027402_10	396588.Tgr7_2182	2.527e-48	181.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria,1WW2H@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM CRISPR-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
CMS2_k127_5027402_7	519989.ECTPHS_11707	3.484e-67	234.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1WZ4B@135613|Chromatiales	135613|Chromatiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS2_k127_5027402_0	1122135.KB893146_gene1780	3.389e-161	527.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,2TSQU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
CMS2_k127_5027402_11	237368.SCABRO_00478	2.413e-29	124.0	COG1388@1|root,COG1388@2|Bacteria,2J2RB@203682|Planctomycetes	203682|Planctomycetes	M	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS2_k127_5038524_10	292415.Tbd_2157	1.769e-41	157.0	COG2010@1|root,COG2010@2|Bacteria,1NE41@1224|Proteobacteria,2WEJ6@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_5038524_0	765911.Thivi_4235	0.0	1114.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria,1X081@135613|Chromatiales	135613|Chromatiales	P	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS2_k127_5038524_7	1049564.TevJSym_aj00700	5.235e-148	471.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1J7ZN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CbbQ/NirQ/NorQ C-terminal	cbbQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
CMS2_k127_5038524_1	870187.Thini_0169	3.449e-294	904.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RYJX@1236|Gammaproteobacteria,46213@72273|Thiotrichales	72273|Thiotrichales	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
CMS2_k127_5038524_9	396588.Tgr7_2883	3.667e-94	312.0	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1WW4H@135613|Chromatiales	135613|Chromatiales	J	PFAM methyltransferase small	-	-	-	-	-	-	-	-	-	-	-	-	MTS,MTS_N
CMS2_k127_5038524_8	261292.Nit79A3_1256	7.652e-124	404.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,372D3@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	cbbR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS2_k127_5038524_4	1049564.TevJSym_an00370	2.863e-204	638.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1J4R3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0191 Fructose tagatose bisphosphate aldolase	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CMS2_k127_5038524_2	105559.Nwat_0283	2.755e-219	689.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales	135613|Chromatiales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS2_k127_5038524_3	1123401.JHYQ01000007_gene528	1.42e-218	683.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,45ZW0@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS2_k127_5038524_5	870187.Thini_2561	1.489e-201	630.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,4604G@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS2_k127_5038524_6	1049564.TevJSym_an00410	1.527e-201	633.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1J4RR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990	Transket_pyr,Transketolase_C,Transketolase_N
CMS2_k127_5084276_1	1123401.JHYQ01000015_gene1405	1.198e-179	568.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales	72273|Thiotrichales	P	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS2_k127_5084276_3	1123401.JHYQ01000015_gene1406	3.357e-157	497.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,45ZUF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM AAA domain (dynein-related subfamily)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
CMS2_k127_5084276_5	1123401.JHYQ01000015_gene1407	4.327e-46	168.0	2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,1SBDA@1236|Gammaproteobacteria,462XP@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5084276_4	243233.MCA2744	5.977e-64	220.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S3XZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
CMS2_k127_5084276_0	1123401.JHYQ01000015_gene1409	3.451e-312	957.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
CMS2_k127_5084276_2	314345.SPV1_12792	1.404e-162	515.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS2_k127_5109178_47	321327.CYA_2592	3.709e-08	61.0	COG2385@1|root,COG2385@2|Bacteria,1G0XG@1117|Cyanobacteria,1H0F9@1129|Synechococcus	1117|Cyanobacteria	D	COG2385 Sporulation protein and related proteins	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
CMS2_k127_5109178_5	373903.Hore_09670	1.165e-183	601.0	COG4953@1|root,COG4953@2|Bacteria	2|Bacteria	M	penicillin binding	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CMS2_k127_5109178_2	373903.Hore_09660	8.679e-246	842.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
CMS2_k127_5109178_10	882378.RBRH_03121	2.277e-166	537.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,1K0Y8@119060|Burkholderiaceae	28216|Betaproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS2_k127_5109178_23	153948.NAL212_2027	1.791e-79	275.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria,371N9@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR	dmlR_8	-	-	ko:K10918,ko:K18900	ko05111,map05111	M00698	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	HTH_1,LysR_substrate
CMS2_k127_5109178_17	1049564.TevJSym_bd00240	2.729e-100	339.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1J55F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the pirin family	XCC2717	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS2_k127_5109178_30	1437882.AZRU01000059_gene4134	3.788e-61	215.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,1YDBI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Cytochrome B561	yceJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
CMS2_k127_5109178_27	765912.Thimo_1583	7.265e-68	242.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,1WXG3@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS2_k127_5109178_21	314278.NB231_11104	9.934e-85	292.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1WYMY@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
CMS2_k127_5109178_28	713586.KB900536_gene2167	2.508e-67	238.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1WY8N@135613|Chromatiales	135613|Chromatiales	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
CMS2_k127_5109178_39	998674.ATTE01000001_gene2628	8.935e-31	129.0	COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,1T4CA@1236|Gammaproteobacteria,463WF@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
CMS2_k127_5109178_14	1232683.ADIMK_2252	7.295e-123	400.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,464JS@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849	Porphobil_deam,Porphobil_deamC
CMS2_k127_5109178_32	631362.Thi970DRAFT_00020	3.048e-59	217.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1WWAM@135613|Chromatiales	135613|Chromatiales	H	Uroporphyrinogen III synthase	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS2_k127_5109178_41	1049564.TevJSym_ak00070	7.706e-26	122.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1J63W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	enzyme of heme biosynthesis	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317	HemX
CMS2_k127_5109178_20	1049564.TevJSym_ak00080	3.129e-92	317.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1J5RD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	enzyme of heme biosynthesis	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
CMS2_k127_5109178_16	1304883.KI912532_gene514	2.728e-117	389.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,2KVA5@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS2_k127_5109178_18	269799.Gmet_0823	7.909e-94	316.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,42QMK@68525|delta/epsilon subdivisions,2X5B1@28221|Deltaproteobacteria,43S4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NmrA
CMS2_k127_5109178_26	1123393.KB891316_gene1129	5.233e-69	241.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS2_k127_5109178_25	187272.Mlg_2567	3.322e-69	243.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1X0WV@135613|Chromatiales	135613|Chromatiales	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
CMS2_k127_5109178_7	857087.Metme_0275	1.097e-174	558.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XEI9@135618|Methylococcales	135618|Methylococcales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS2_k127_5109178_19	1049564.TevJSym_at00270	4.053e-93	319.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1J4S5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG4942 Membrane-bound metallopeptidase	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_5109178_3	1049564.TevJSym_at00260	4.895e-233	730.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1J4GC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_3895,iJN746.PP_5056	Metalloenzyme,Phosphodiest,iPGM_N
CMS2_k127_5109178_35	395493.BegalDRAFT_1766	1.117e-45	166.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,4613Z@72273|Thiotrichales	72273|Thiotrichales	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS2_k127_5109178_38	1123368.AUIS01000003_gene1732	5.608e-37	145.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,2NCVA@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_5109178_44	1123053.AUDG01000008_gene3630	1.166e-22	102.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1WZFE@135613|Chromatiales	135613|Chromatiales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
CMS2_k127_5109178_31	1123257.AUFV01000016_gene3542	6.473e-61	213.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1X6VW@135614|Xanthomonadales	135614|Xanthomonadales	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
CMS2_k127_5109178_33	472759.Nhal_0026	2.002e-58	207.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1WY33@135613|Chromatiales	135613|Chromatiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
CMS2_k127_5109178_15	472759.Nhal_0027	2.419e-121	398.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1WXMZ@135613|Chromatiales	135613|Chromatiales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS2_k127_5109178_24	589873.EP13_02385	2.997e-69	237.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,46713@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS2_k127_5109178_9	2340.JV46_11900	9.01e-168	533.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1J5J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,NAD_binding_1
CMS2_k127_5109178_45	338963.Pcar_2056	1.14e-19	94.0	COG5430@1|root,COG5430@2|Bacteria,1Q657@1224|Proteobacteria,432EY@68525|delta/epsilon subdivisions,2WYB4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
CMS2_k127_5109178_11	338963.Pcar_2057	7.528e-155	519.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,42WF9@68525|delta/epsilon subdivisions,2WRD4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Outer membrane usher protein	csuD	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	Usher
CMS2_k127_5109178_34	338963.Pcar_2058	4.087e-58	211.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
CMS2_k127_5109178_4	1357272.AVEO02000157_gene1918	2.897e-219	689.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1Z5DH@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	T	nitrogen regulation protein	glnG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_5109178_12	519989.ECTPHS_01379	1.637e-126	415.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
CMS2_k127_5109178_46	472759.Nhal_0552	1.127e-11	72.0	2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,1WZCE@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,DUF4124
CMS2_k127_5109178_1	870187.Thini_3228	8.943e-261	808.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,45ZRY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS2_k127_5109178_13	2340.JV46_17540	2.325e-124	409.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1J70K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS2_k127_5109178_40	930169.B5T_00620	6.318e-28	115.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
CMS2_k127_5109178_6	857087.Metme_0468	2.783e-178	563.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,1XEUN@135618|Methylococcales	135618|Methylococcales	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	ThiI
CMS2_k127_5109178_8	1049564.TevJSym_aq00100	7.55e-173	551.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1J50F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	glycyl-tRNA synthetase, alpha subunit	glyQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF1260.b3560,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360	tRNA-synt_2e
CMS2_k127_5109178_0	396588.Tgr7_3255	7.39e-265	832.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales	135613|Chromatiales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS2_k127_5109178_36	1049564.TevJSym_aq00120	1.088e-44	164.0	2F88A@1|root,340MG@2|Bacteria,1NXS1@1224|Proteobacteria,1SQ1P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS2_k127_5109178_29	472759.Nhal_0220	9.615e-67	232.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1WY8W@135613|Chromatiales	135613|Chromatiales	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
CMS2_k127_5109178_22	105559.Nwat_2728	9.808e-81	276.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1WXP3@135613|Chromatiales	135613|Chromatiales	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS2_k127_5118129_30	1137799.GZ78_00170	1.14e-20	100.0	2BZY2@1|root,2ZMII@2|Bacteria,1P6VB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5118129_21	1137799.GZ78_00175	2.246e-70	253.0	COG4783@1|root,COG4783@2|Bacteria,1RAJB@1224|Proteobacteria,1SA1F@1236|Gammaproteobacteria,1XPS8@135619|Oceanospirillales	135619|Oceanospirillales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS2_k127_5118129_29	1248760.ANFZ01000006_gene2339	2.244e-21	103.0	2EDW0@1|root,337R6@2|Bacteria,1N9FY@1224|Proteobacteria,2UFB9@28211|Alphaproteobacteria,2K24M@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5118129_20	870187.Thini_0155	2.044e-72	250.0	28Z54@1|root,2ZKXF@2|Bacteria,1RAVB@1224|Proteobacteria,1S46P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	-
CMS2_k127_5118129_3	765911.Thivi_0695	3.616e-270	865.0	COG2202@1|root,COG3614@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WXCR@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CZB,EAL,GGDEF,PAS_3,PAS_4,PAS_9
CMS2_k127_5118129_10	159087.Daro_1440	1.946e-163	524.0	COG0683@1|root,COG0683@2|Bacteria,1N11P@1224|Proteobacteria,2VJY3@28216|Betaproteobacteria	28216|Betaproteobacteria	E	abc-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,TAT_signal
CMS2_k127_5118129_4	203122.Sde_0575	1.229e-222	720.0	COG1061@1|root,COG1061@2|Bacteria,1P2PG@1224|Proteobacteria,1S17N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
CMS2_k127_5118129_26	1286106.MPL1_10843	6.809e-33	135.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria	1224|Proteobacteria	S	Outer Membrane Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
CMS2_k127_5118129_32	713586.KB900536_gene2283	2.986e-09	61.0	2913D@1|root,2ZNQV@2|Bacteria,1P4TF@1224|Proteobacteria,1SV4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5118129_15	519989.ECTPHS_11687	3.172e-92	307.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1WXK5@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07660	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS2_k127_5118129_14	768671.ThimaDRAFT_2857	1.118e-120	401.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1X2PK@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07637	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c
CMS2_k127_5118129_12	1288494.EBAPG3_2370	4.584e-127	424.0	28H91@1|root,2Z7KU@2|Bacteria,1R4NB@1224|Proteobacteria,2VS45@28216|Betaproteobacteria,373Z4@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5118129_16	1266925.JHVX01000012_gene1696	7.906e-87	291.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,2VRDD@28216|Betaproteobacteria,3731E@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
CMS2_k127_5118129_22	76114.ebA872	4.043e-65	229.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,2VRHA@28216|Betaproteobacteria,2KYN1@206389|Rhodocyclales	206389|Rhodocyclales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS2_k127_5118129_23	765913.ThidrDRAFT_1276	1.971e-56	203.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1WYPS@135613|Chromatiales	135613|Chromatiales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS2_k127_5118129_2	338963.Pcar_0543	1.249e-279	883.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,43URK@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CMS2_k127_5118129_0	338963.Pcar_0544	0.0	1986.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,43VRH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
CMS2_k127_5118129_24	1121374.KB891575_gene1067	4.646e-55	200.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,1S2RR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS2_k127_5118129_25	930169.B5T_01174	4.442e-53	197.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,1XNUR@135619|Oceanospirillales	135619|Oceanospirillales	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS2_k127_5118129_19	1033802.SSPSH_003006	1.338e-77	264.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS2_k127_5118129_13	580332.Slit_2221	6.037e-124	404.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities AAA_3	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS2_k127_5118129_18	1163617.SCD_n01286	9.672e-79	274.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS2_k127_5118129_9	395493.BegalDRAFT_1364	1.623e-165	543.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,45ZZC@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
CMS2_k127_5118129_8	1122599.AUGR01000002_gene3346	2.742e-175	559.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XI7M@135619|Oceanospirillales	135619|Oceanospirillales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS2_k127_5118129_6	396588.Tgr7_3318	8.925e-187	598.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales	135613|Chromatiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS2_k127_5118129_27	870187.Thini_2788	8.46e-29	117.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,4615Y@72273|Thiotrichales	72273|Thiotrichales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS2_k127_5118129_28	675813.VIB_003024	1.804e-26	113.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1XXEW@135623|Vibrionales	135623|Vibrionales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS2_k127_5118129_31	2340.JV46_22900	2.155e-14	74.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1J78H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS2_k127_5118129_5	396588.Tgr7_0001	7.852e-209	657.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales	135613|Chromatiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS2_k127_5118129_11	1027273.GZ77_22125	6.046e-139	450.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales	135619|Oceanospirillales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS2_k127_5118129_17	1499686.BN1079_02586	2.637e-80	280.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CMS2_k127_5118129_1	2340.JV46_17100	0.0	1177.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1J4W4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS2_k127_5118129_7	765910.MARPU_02205	3.115e-186	586.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1WXJM@135613|Chromatiales	135613|Chromatiales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
CMS2_k127_5141691_6	631362.Thi970DRAFT_01489	1.422e-14	78.0	COG3905@1|root,COG3905@2|Bacteria,1QB1J@1224|Proteobacteria,1RW4N@1236|Gammaproteobacteria,1WZUX@135613|Chromatiales	135613|Chromatiales	K	copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
CMS2_k127_5141691_5	864073.HFRIS_022703	2.156e-39	149.0	COG1487@1|root,COG1487@2|Bacteria,1MZCD@1224|Proteobacteria,2VXRA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS2_k127_5141691_2	29581.BW37_00332	3.238e-224	700.0	28HIY@1|root,2Z7U8@2|Bacteria,1MY3K@1224|Proteobacteria,2VKE4@28216|Betaproteobacteria,476KW@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5141691_0	395493.BegalDRAFT_0242	0.0	1499.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS2_k127_5141691_3	713586.KB900536_gene1063	3.595e-88	304.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1WX31@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS2_k127_5141691_4	338969.Rfer_1825	2.449e-67	250.0	COG0784@1|root,COG2203@1|root,COG5001@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AH82@80864|Comamonadaceae	28216|Betaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,Response_reg
CMS2_k127_5141691_1	765913.ThidrDRAFT_0387	7.731e-301	928.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_5154801_1	1122207.MUS1_05195	6.724e-259	803.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1XIGG@135619|Oceanospirillales	135619|Oceanospirillales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	nrtC	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
CMS2_k127_5154801_4	768671.ThimaDRAFT_4414	1.183e-138	448.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1X02E@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
CMS2_k127_5154801_5	1283300.ATXB01000002_gene2683	2.286e-133	430.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,1XEX0@135618|Methylococcales	135618|Methylococcales	P	TIGRFAM Nitrate transport ATP-binding	-	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
CMS2_k127_5154801_3	768671.ThimaDRAFT_4416	5.499e-192	608.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1X036@135613|Chromatiales	135613|Chromatiales	P	NMT1-like family	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
CMS2_k127_5154801_0	243233.MCA0592	0.0	1178.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XDM1@135618|Methylococcales	135618|Methylococcales	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
CMS2_k127_5154801_6	1120963.KB894491_gene1118	2.634e-47	173.0	COG2346@1|root,COG2346@2|Bacteria,1QBDE@1224|Proteobacteria,1S9FC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Group 1 truncated hemoglobin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS2_k127_5154801_7	1395516.PMO01_08895	4.475e-41	154.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,1S9CV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	nitrite reductase	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
CMS2_k127_5154801_2	1286106.MPL1_10507	3.724e-198	626.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS2_k127_5260210_6	864565.HMPREF0379_0858	5.98e-21	107.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25QJS@186804|Peptostreptococcaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS2_k127_5260210_4	378806.STAUR_1428	4.738e-42	160.0	COG4385@1|root,COG4385@2|Bacteria,1N0CW@1224|Proteobacteria,42UPU@68525|delta/epsilon subdivisions,2WR0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
CMS2_k127_5260210_0	1121405.dsmv_1282	5.372e-258	821.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,42QGQ@68525|delta/epsilon subdivisions,2WIVM@28221|Deltaproteobacteria,2MMI8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CMS2_k127_5260210_3	1121405.dsmv_1281	1.171e-47	175.0	COG3628@1|root,COG3628@2|Bacteria,1NCAC@1224|Proteobacteria,42TW2@68525|delta/epsilon subdivisions,2WQR5@28221|Deltaproteobacteria,2MNY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
CMS2_k127_5260210_5	314278.NB231_03485	6.892e-38	146.0	2E7P5@1|root,3324R@2|Bacteria,1NEZR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5260210_1	1121405.dsmv_1279	9.854e-141	463.0	COG3501@1|root,COG3501@2|Bacteria,1Q96K@1224|Proteobacteria,42RTE@68525|delta/epsilon subdivisions,2WNJ9@28221|Deltaproteobacteria,2MMJ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD,Phage_base_V
CMS2_k127_5260210_2	338963.Pcar_2893	1.231e-60	218.0	COG1652@1|root,COG1652@2|Bacteria,1RK4N@1224|Proteobacteria,42UDJ@68525|delta/epsilon subdivisions,2WR1I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5287826_6	1129794.C427_3200	1.07e-08	56.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,4650N@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS2_k127_5287826_3	765914.ThisiDRAFT_0953	6.992e-59	213.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,1S60V@1236|Gammaproteobacteria,1WYHQ@135613|Chromatiales	135613|Chromatiales	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS2_k127_5287826_1	713586.KB900536_gene819	4.136e-227	711.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WW29@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0027	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS2_k127_5287826_4	1123393.KB891316_gene1686	7.236e-52	187.0	COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease,HD,PolyA_pol,PolyA_pol_RNAbd
CMS2_k127_5287826_2	1049564.TevJSym_aa02050	1.898e-76	263.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1J669@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS2_k127_5287826_5	87626.PTD2_06294	6.304e-28	121.0	COG4625@1|root,COG4625@2|Bacteria,1N0QY@1224|Proteobacteria,1RWPB@1236|Gammaproteobacteria,2Q4TU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5287826_0	1049564.TevJSym_bw00090	1.914e-250	788.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1J5D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KL	HELICc2	yoaA	GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
CMS2_k127_5320047_21	1122212.AULO01000009_gene986	1.979e-06	49.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XICF@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS2_k127_5320047_9	1279015.KB908463_gene2059	2.754e-111	369.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1Y6I9@135624|Aeromonadales	135624|Aeromonadales	J	tRNA synthetases class II (D, K and N)	-	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
CMS2_k127_5320047_12	1260251.SPISAL_06520	4.705e-94	310.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales	135613|Chromatiales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS2_k127_5320047_5	1384054.N790_06905	3.045e-122	400.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1X3RU@135614|Xanthomonadales	135614|Xanthomonadales	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS2_k127_5320047_3	396588.Tgr7_1229	5.537e-159	527.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales	135613|Chromatiales	T	PFAM EAL domain	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
CMS2_k127_5320047_6	1123368.AUIS01000003_gene1816	3.745e-122	397.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,2NBV2@225057|Acidithiobacillales	1236|Gammaproteobacteria	O	Peptidase family M48	htpX	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS2_k127_5320047_10	1042377.AFPJ01000037_gene2939	4.866e-109	371.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
CMS2_k127_5320047_0	1215092.PA6_017_00540	0.0	1137.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1YEVJ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS2_k127_5320047_1	2340.JV46_29190	0.0	1034.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS2_k127_5320047_7	1232683.ADIMK_3705	7.264e-121	391.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,465CK@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735	SAICAR_synt
CMS2_k127_5320047_11	754477.Q7C_2628	4.474e-95	318.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,460KN@72273|Thiotrichales	72273|Thiotrichales	S	of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS2_k127_5320047_14	323848.Nmul_A1539	6.081e-68	244.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,371WT@32003|Nitrosomonadales	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
CMS2_k127_5320047_4	396588.Tgr7_0827	2.697e-135	439.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1WWMV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS2_k127_5320047_15	1049564.TevJSym_ax00210	2.137e-66	231.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1JBWT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ACT domain	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT,ACT_6
CMS2_k127_5320047_13	472759.Nhal_0649	1.118e-69	239.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WY4F@135613|Chromatiales	135613|Chromatiales	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS2_k127_5320047_2	519989.ECTPHS_00095	1.269e-226	710.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales	135613|Chromatiales	T	SMART Nucleotide binding protein, PINc	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CMS2_k127_5320047_8	1288826.MSNKSG1_04051	1.543e-112	366.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS2_k127_5320047_17	519989.ECTPHS_08958	5.554e-47	175.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,1S9MI@1236|Gammaproteobacteria,1WYGK@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
CMS2_k127_5320047_19	319225.Plut_0724	7.061e-12	72.0	COG1607@1|root,COG1607@2|Bacteria,1FEAZ@1090|Chlorobi	1090|Chlorobi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS2_k127_5320047_16	765911.Thivi_3025	5.292e-64	222.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1WYEZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS2_k127_5321408_13	1343740.M271_41895	1.164e-11	78.0	COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
CMS2_k127_5321408_9	946483.Cenrod_0355	1.307e-73	264.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2VK83@28216|Betaproteobacteria,4AEXG@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, family 2	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Cellulose_synt,Glyco_tranf_2_3,Glycos_transf_2
CMS2_k127_5321408_6	1049564.TevJSym_as00320	1.08e-94	318.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1J5TZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS2_k127_5321408_7	76114.ebA6680	3.659e-76	261.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VRUU@28216|Betaproteobacteria,2KWI9@206389|Rhodocyclales	206389|Rhodocyclales	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS2_k127_5321408_8	472759.Nhal_1185	1.262e-73	257.0	COG1985@1|root,COG1985@2|Bacteria,1RDMT@1224|Proteobacteria,1S4SQ@1236|Gammaproteobacteria,1X05Z@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS2_k127_5321408_1	314345.SPV1_11751	4.404e-289	894.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria	1224|Proteobacteria	C	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2,Pyr_redox_3
CMS2_k127_5321408_0	314345.SPV1_11756	0.0	1883.0	COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1MVM0@1224|Proteobacteria	1224|Proteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS2_k127_5321408_2	1123517.JOMR01000001_gene1257	7.913e-233	726.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,45ZN5@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS2_k127_5321408_3	1123368.AUIS01000023_gene933	1.775e-189	626.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
CMS2_k127_5321408_10	765913.ThidrDRAFT_0272	1.03e-61	214.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1WYEZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS2_k127_5321408_12	1049564.TevJSym_ab00860	3.593e-46	169.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1S3Z2@1236|Gammaproteobacteria,1J6KI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS2_k127_5321408_11	396588.Tgr7_2638	7.818e-48	175.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,1S9MI@1236|Gammaproteobacteria,1WYGK@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
CMS2_k127_5321408_5	1288826.MSNKSG1_04051	7.4e-113	366.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS2_k127_5321408_4	1049564.TevJSym_ax00230	8.675e-123	396.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1J555@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CMS2_k127_5359225_8	338969.Rfer_1693	1.245e-53	198.0	2E1GC@1|root,32WUU@2|Bacteria,1N0XG@1224|Proteobacteria,2VX7K@28216|Betaproteobacteria,4AFSZ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5359225_20	340177.Cag_0596	1.319e-07	53.0	COG3153@1|root,COG3153@2|Bacteria,1FE06@1090|Chlorobi	1090|Chlorobi	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS2_k127_5359225_21	313612.L8106_22596	1.544e-07	53.0	COG3153@1|root,COG3153@2|Bacteria,1G6H9@1117|Cyanobacteria,1HBUU@1150|Oscillatoriales	1117|Cyanobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
CMS2_k127_5359225_10	1116472.MGMO_92c00280	4.321e-51	186.0	291PZ@1|root,2ZPA3@2|Bacteria,1RE76@1224|Proteobacteria,1S5CT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5359225_12	1415780.JPOG01000001_gene816	1.018e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_5359225_15	1415780.JPOG01000001_gene815	3.547e-21	101.0	COG5662@1|root,COG5662@2|Bacteria,1NGBV@1224|Proteobacteria,1SGXN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS2_k127_5359225_11	1415754.JQMK01000002_gene2506	7.98e-42	170.0	COG0457@1|root,COG0457@2|Bacteria,1N8R8@1224|Proteobacteria,1SBTP@1236|Gammaproteobacteria,468VH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS2_k127_5359225_1	105559.Nwat_1801	4.938e-207	655.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS2_k127_5359225_5	1141662.OOA_15270	9.605e-81	289.0	COG2194@1|root,COG2194@2|Bacteria,1MWJY@1224|Proteobacteria,1RN4T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cellulose synthase operon protein YhjU	bcsG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBP_BcsG
CMS2_k127_5359225_18	519989.ECTPHS_00779	1.002e-09	72.0	COG3118@1|root,COG3118@2|Bacteria,1PG6K@1224|Proteobacteria,1TKBC@1236|Gammaproteobacteria,1X1HM@135613|Chromatiales	135613|Chromatiales	O	Cellulose synthase operon protein C C-terminus (BCSC_C)	-	-	-	-	-	-	-	-	-	-	-	-	BCSC_C
CMS2_k127_5359225_4	1279038.KB907347_gene3214	2.349e-89	306.0	COG3405@1|root,COG3405@2|Bacteria,1MW17@1224|Proteobacteria,2TSZH@28211|Alphaproteobacteria,2JRXI@204441|Rhodospirillales	204441|Rhodospirillales	G	Glycosyl hydrolases family 8	-	-	3.2.1.4	ko:K20542	-	-	-	-	ko00000,ko01000	-	GH8	-	Glyco_hydro_8
CMS2_k127_5359225_2	1279038.KB907347_gene3213	2.386e-125	429.0	COG3266@1|root,COG3266@2|Bacteria,1NAC9@1224|Proteobacteria,2TZK5@28211|Alphaproteobacteria,2JTJ3@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial cellulose synthase subunit	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB
CMS2_k127_5359225_0	519989.ECTPHS_11757	2.015e-262	827.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,1S08E@1236|Gammaproteobacteria,1WXTS@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS2_k127_5359225_17	243159.AFE_2575	7.463e-11	72.0	2DBSQ@1|root,2ZATE@2|Bacteria,1R57P@1224|Proteobacteria,1T004@1236|Gammaproteobacteria,2NBU8@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5359225_6	1123400.KB904747_gene413	5.739e-65	227.0	COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1S271@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
CMS2_k127_5359225_3	575540.Isop_1679	1.811e-100	343.0	COG1117@1|root,COG2453@1|root,COG1117@2|Bacteria,COG2453@2|Bacteria,2J01Y@203682|Planctomycetes	203682|Planctomycetes	T	Protein-tyrosine phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc
CMS2_k127_5359225_7	365044.Pnap_0368	3.106e-56	199.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5359225_14	395493.BegalDRAFT_1587	4.787e-28	118.0	COG2018@1|root,COG2018@2|Bacteria,1RIQC@1224|Proteobacteria,1S65Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
CMS2_k127_5359225_9	40215.BBOS01000010_gene3132	6.072e-53	197.0	COG1018@1|root,COG2346@1|root,COG1018@2|Bacteria,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	-	-	-	ko:K06886,ko:K07006	-	-	-	-	ko00000	-	-	-	Bac_globin,DUF4445,Fer2
CMS2_k127_5359225_16	631362.Thi970DRAFT_04272	6.548e-20	91.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1WYUC@135613|Chromatiales	135613|Chromatiales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
CMS2_k127_5359225_13	1123518.ARWI01000001_gene1913	5.833e-31	127.0	2BKN5@1|root,32F3J@2|Bacteria,1RIMC@1224|Proteobacteria,1S6Q3@1236|Gammaproteobacteria,463R5@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS2_k127_5369136_26	1049564.TevJSym_ai00610	1.596e-23	102.0	COG3313@1|root,COG3313@2|Bacteria	2|Bacteria	S	Fe-S protein	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
CMS2_k127_5369136_5	870187.Thini_3935	3.736e-118	390.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales	72273|Thiotrichales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_5369136_25	1049564.TevJSym_bf00160	1.083e-25	113.0	28P01@1|root,338A2@2|Bacteria,1NBSK@1224|Proteobacteria,1SS2R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5369136_15	443144.GM21_0845	3.002e-60	220.0	COG2199@1|root,COG3706@2|Bacteria,1REIE@1224|Proteobacteria	1224|Proteobacteria	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,cNMP_binding
CMS2_k127_5369136_14	1419583.V466_19375	2.088e-62	222.0	COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,1YQ71@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	Q	Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family	tpm	GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
CMS2_k127_5369136_3	1415778.JQMM01000001_gene249	3.988e-135	451.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1J52N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS2_k127_5369136_7	1232410.KI421428_gene1003	1.48e-102	347.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,43TKF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS2_k127_5369136_16	1049564.TevJSym_ag00720	1.591e-42	161.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1J67K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS2_k127_5369136_29	859657.RPSI07_2264	0.0003959	49.0	COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,2VU14@28216|Betaproteobacteria,1K787@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS2_k127_5369136_18	926550.CLDAP_30490	2.534e-38	151.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS2_k127_5369136_22	882083.SacmaDRAFT_3545	1.439e-29	128.0	COG4319@1|root,COG4319@2|Bacteria,2HS8I@201174|Actinobacteria,4ECWB@85010|Pseudonocardiales	201174|Actinobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS2_k127_5369136_0	1049564.TevJSym_ap00150	3.207e-314	973.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1J55U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	pcoA	-	-	-	-	-	-	-	-	-	-	-	CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS2_k127_5369136_10	1049564.TevJSym_ap00140	8.261e-82	282.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,1RZEY@1236|Gammaproteobacteria,1J66N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Copper resistance protein B precursor (CopB)	copB	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
CMS2_k127_5369136_21	1001530.BACE01000012_gene2507	1.125e-30	126.0	2C7FC@1|root,32S1T@2|Bacteria,1N1DJ@1224|Proteobacteria,1S96F@1236|Gammaproteobacteria,1XYH2@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5369136_2	713586.KB900536_gene2819	2.175e-135	445.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS2_k127_5369136_8	344747.PM8797T_30881	1.552e-99	341.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8
CMS2_k127_5369136_24	768671.ThimaDRAFT_3727	9.65e-26	109.0	2A022@1|root,30N4C@2|Bacteria,1PU9F@1224|Proteobacteria,1SCMU@1236|Gammaproteobacteria,1WYYW@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
CMS2_k127_5369136_6	1123401.JHYQ01000001_gene1797	2.237e-116	394.0	COG0220@1|root,COG0220@2|Bacteria,1QYIP@1224|Proteobacteria,1T5B9@1236|Gammaproteobacteria,463MF@72273|Thiotrichales	72273|Thiotrichales	J	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg
CMS2_k127_5369136_28	65393.PCC7424_0768	1.302e-06	55.0	COG0727@1|root,COG0727@2|Bacteria,1GFCE@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
CMS2_k127_5369136_1	28072.Nos7524_0264	1.004e-220	692.0	arCOG06766@1|root,2Z87F@2|Bacteria,1G1NX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5369136_19	452637.Oter_1072	9.077e-34	135.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C,GMC_oxred_N,NAD_binding_8,Pyr_redox_2
CMS2_k127_5369136_23	247633.GP2143_17146	2.801e-27	113.0	COG3141@1|root,COG3141@2|Bacteria,1N26M@1224|Proteobacteria,1SCRN@1236|Gammaproteobacteria,1J6XY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	YebG protein	-	-	-	ko:K09918	-	-	-	-	ko00000	-	-	-	YebG
CMS2_k127_5369136_13	2340.JV46_25240	1.754e-64	227.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RXB4@1236|Gammaproteobacteria,1JAMN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS2_k127_5369136_4	406817.XNC1_1068	3.096e-133	443.0	COG0488@1|root,COG0488@2|Bacteria,1MV25@1224|Proteobacteria,1RNM9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase components of ABC transporters with duplicated ATPase domains	ydiF	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS2_k127_5369136_11	1502852.FG94_01361	3.257e-81	284.0	COG2199@1|root,COG3159@1|root,COG3159@2|Bacteria,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,2VJGD@28216|Betaproteobacteria,472P5@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Protein of unknown function, DUF484	-	-	-	-	-	-	-	-	-	-	-	-	DUF484,GGDEF
CMS2_k127_5369136_9	1123393.KB891326_gene8	1.845e-97	326.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2VIY0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS2_k127_5433789_3	314262.MED193_15617	1.782e-127	441.0	COG0463@1|root,COG0463@2|Bacteria,1R6H4@1224|Proteobacteria,2U3GR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Galactosyl_T,Glyco_tranf_2_4
CMS2_k127_5433789_12	65393.PCC7424_4200	2.228e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1G6BT@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS2_k127_5433789_14	1469613.JT55_03025	0.0004865	51.0	2DW2G@1|root,33Y94@2|Bacteria,1NWSW@1224|Proteobacteria,2US94@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5433789_8	351348.Maqu_2626	2.056e-54	204.0	COG1874@1|root,COG1874@2|Bacteria,1QZBG@1224|Proteobacteria,1SEM8@1236|Gammaproteobacteria,46D73@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5433789_10	102125.Xen7305DRAFT_00024840	2.04e-33	139.0	COG4424@1|root,COG4424@2|Bacteria,1GAUA@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Stf0 sulphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulphotransf
CMS2_k127_5433789_5	713586.KB900536_gene897	9.898e-88	295.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1WY0V@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS2_k127_5433789_7	998088.B565_1534	1.808e-70	252.0	COG0438@1|root,COG0438@2|Bacteria,1R662@1224|Proteobacteria,1RREQ@1236|Gammaproteobacteria,1Y5RM@135624|Aeromonadales	135624|Aeromonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5433789_0	1265502.KB905969_gene1227	3.106e-220	703.0	COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,2VKAF@28216|Betaproteobacteria,4AHCR@80864|Comamonadaceae	28216|Betaproteobacteria	M	Capsule polysaccharide biosynthesis protein	wcbA	-	-	ko:K07266	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS2_k127_5433789_2	859657.RPSI07_2516	8.58e-152	492.0	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,2VN14@28216|Betaproteobacteria,1K2IM@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Capsule polysaccharide biosynthesis protein	-	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS2_k127_5433789_4	243231.GSU0804	2.544e-94	312.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,42PF5@68525|delta/epsilon subdivisions,2WMD8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the WrbA family	wrbA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0771	FMN_red
CMS2_k127_5433789_13	156578.ATW7_16388	2.343e-07	56.0	2DQTB@1|root,338HR@2|Bacteria,1NE36@1224|Proteobacteria,1SDPX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS2_k127_5433789_1	644801.Psest_2547	4.081e-177	574.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1Z0BX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5
CMS2_k127_5433789_9	1163617.SCD_n01511	2.796e-45	166.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS2_k127_5433789_6	1121943.KB900006_gene2791	8.97e-86	287.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1XJ7X@135619|Oceanospirillales	135619|Oceanospirillales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS2_k127_5468156_3	626887.J057_16395	1.09e-72	249.0	COG0454@1|root,COG0456@2|Bacteria,1RIAQ@1224|Proteobacteria,1T12P@1236|Gammaproteobacteria,46BCK@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS2_k127_5468156_7	713586.KB900536_gene1456	8.708e-57	204.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,1WZFI@135613|Chromatiales	135613|Chromatiales	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS2_k127_5468156_5	479434.Sthe_3482	3.27e-63	233.0	COG2041@1|root,COG2041@2|Bacteria,2GB1N@200795|Chloroflexi,27Z7Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS2_k127_5468156_2	1163617.SCD_n02275	3.576e-84	287.0	COG1187@1|root,COG1187@2|Bacteria,1PYTZ@1224|Proteobacteria,2VNU1@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	S4
CMS2_k127_5468156_14	1089439.KB902239_gene506	2.493e-07	54.0	2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5468156_6	755178.Cyan10605_3253	2.441e-62	218.0	COG0229@1|root,COG0229@2|Bacteria,1G62Y@1117|Cyanobacteria	1117|Cyanobacteria	O	peptide methionine sulfoxide reductase	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS2_k127_5468156_1	1254432.SCE1572_16000	7.281e-130	434.0	COG3386@1|root,COG3386@2|Bacteria,1QUU9@1224|Proteobacteria,42ZTS@68525|delta/epsilon subdivisions,2WVGZ@28221|Deltaproteobacteria,2YZAH@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5468156_4	580332.Slit_1224	1.559e-71	248.0	2C6BU@1|root,32S87@2|Bacteria,1NIFE@1224|Proteobacteria,2VRGB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5468156_13	1049564.TevJSym_aa01730	6.271e-10	65.0	2E189@1|root,32WNT@2|Bacteria,1N4GY@1224|Proteobacteria,1SBNR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5468156_0	1198232.CYCME_0496	2.021e-135	435.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,460K1@72273|Thiotrichales	72273|Thiotrichales	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
CMS2_k127_5468156_11	1123261.AXDW01000009_gene160	5.114e-20	97.0	2DRXB@1|root,33DI0@2|Bacteria,1R3JR@1224|Proteobacteria,1SJ2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5468156_9	1448139.AI20_18380	1.684e-37	146.0	2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2846
CMS2_k127_5468156_8	28229.ND2E_0651	2.689e-41	161.0	2DMIF@1|root,32RSM@2|Bacteria,1N32G@1224|Proteobacteria,1SAQP@1236|Gammaproteobacteria,2Q6T7@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
CMS2_k127_5468156_10	1408445.JHXP01000017_gene3286	2.377e-26	111.0	COG1396@1|root,COG1396@2|Bacteria,1N8ZM@1224|Proteobacteria,1S8EN@1236|Gammaproteobacteria,1JF49@118969|Legionellales	118969|Legionellales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS2_k127_5468156_15	1123393.KB891326_gene8	5.352e-07	53.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2VIY0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS2_k127_5484096_11	1158760.AQXP01000029_gene825	1.523e-111	366.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1WWM6@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS2_k127_5484096_26	870187.Thini_1576	2.006e-51	183.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,460V9@72273|Thiotrichales	72273|Thiotrichales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
CMS2_k127_5484096_38	1198232.CYCME_1032	3.196e-07	57.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,462CF@72273|Thiotrichales	72273|Thiotrichales	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
CMS2_k127_5484096_5	754477.Q7C_1329	5.284e-154	493.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,45ZXT@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
CMS2_k127_5484096_2	768671.ThimaDRAFT_1712	2.131e-250	782.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1WWS0@135613|Chromatiales	135613|Chromatiales	P	inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS2_k127_5484096_7	754476.Q7A_3042	3.78e-144	465.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,45ZZ9@72273|Thiotrichales	72273|Thiotrichales	E	Ferric iron ABC transporter, ATP-binding protein	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS2_k127_5484096_3	1049564.TevJSym_as00390	4.578e-209	660.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1J4I5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	gtrB	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS2_k127_5484096_22	765912.Thimo_0632	3.124e-59	210.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1WXYX@135613|Chromatiales	135613|Chromatiales	Q	TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS2_k127_5484096_12	1266925.JHVX01000003_gene558	1.735e-108	359.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,37292@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS2_k127_5484096_32	395493.BegalDRAFT_1554	1.563e-21	99.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,46193@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
CMS2_k127_5484096_8	187272.Mlg_2861	3.983e-118	383.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS2_k127_5484096_9	748247.AZKH_0352	7.757e-117	383.0	COG2010@1|root,COG2010@2|Bacteria,1R48P@1224|Proteobacteria,2VPF4@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
CMS2_k127_5484096_14	864051.BurJ1DRAFT_4162	1.182e-99	336.0	COG2010@1|root,COG2010@2|Bacteria,1R6Z0@1224|Proteobacteria,2VRTH@28216|Betaproteobacteria,1KNJH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,DUF302
CMS2_k127_5484096_31	864051.BurJ1DRAFT_4158	3.581e-23	109.0	COG3303@1|root,COG3303@2|Bacteria,1NEPE@1224|Proteobacteria,2VVS8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS2_k127_5484096_13	748247.AZKH_0348	8.384e-104	348.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VNUX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS2_k127_5484096_4	864051.BurJ1DRAFT_4194	1.021e-163	524.0	COG3292@1|root,COG3292@2|Bacteria,1N0TN@1224|Proteobacteria,2VMZM@28216|Betaproteobacteria,1KNDQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS2_k127_5484096_6	864051.BurJ1DRAFT_4193	5.74e-149	480.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,2VPDV@28216|Betaproteobacteria,1KMX9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS2_k127_5484096_35	395495.Lcho_4116	3.052e-13	73.0	COG2010@1|root,COG2010@2|Bacteria,1NATR@1224|Proteobacteria,2VXA9@28216|Betaproteobacteria,1KP7S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_5484096_30	1415754.JQMK01000005_gene1635	1.275e-26	116.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SBMS@1236|Gammaproteobacteria,46CHU@72275|Alteromonadaceae	1236|Gammaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_5484096_36	269799.Gmet_3526	6.641e-10	68.0	COG4765@1|root,COG4765@2|Bacteria,1N5MU@1224|Proteobacteria,42TQ6@68525|delta/epsilon subdivisions,2WR2C@28221|Deltaproteobacteria,43VB1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2155)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2155
CMS2_k127_5484096_17	267608.RSc2985	3.973e-87	299.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,1K2Y8@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Pfam Cytochrome C assembly protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS2_k127_5484096_19	1485545.JQLW01000005_gene962	4.745e-72	264.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria	1224|Proteobacteria	O	PFAM ResB family protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS2_k127_5484096_28	748247.AZKH_0336	7.769e-38	151.0	COG0457@1|root,COG0457@2|Bacteria,1N986@1224|Proteobacteria,2VWWW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS2_k127_5484096_23	1223521.BBJX01000002_gene2865	4.399e-59	222.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,2VKFW@28216|Betaproteobacteria,4AH9U@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CMS2_k127_5484096_10	748247.AZKH_0338	1.258e-112	374.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,2KZCZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS2_k127_5484096_21	1211579.PP4_30960	1.35e-64	248.0	COG0421@1|root,COG0421@2|Bacteria,1QVJA@1224|Proteobacteria,1RYYT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS2_k127_5484096_16	748247.AZKH_0339	5.882e-94	318.0	COG1333@1|root,COG1333@2|Bacteria,1RKRF@1224|Proteobacteria,2VTE4@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cytochrome c biogenesis protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS2_k127_5484096_1	864051.BurJ1DRAFT_4175	9.821e-252	800.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria,1KN2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS2_k127_5484096_15	748247.AZKH_0340	1.454e-98	332.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,2VNCM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5484096_33	1158338.JNLJ01000001_gene945	2.623e-16	90.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TPR_11
CMS2_k127_5484096_27	864051.BurJ1DRAFT_4171	1.806e-42	161.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria,2VTRB@28216|Betaproteobacteria,1KNNN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS2_k127_5484096_29	748247.AZKH_0332	6.312e-34	145.0	2CJJV@1|root,30VBX@2|Bacteria,1RGSF@1224|Proteobacteria,2VS5D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5484096_18	748247.AZKH_0333	3.307e-72	249.0	COG3245@1|root,COG3245@2|Bacteria,1RCEB@1224|Proteobacteria,2VQIB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3
CMS2_k127_5484096_24	748247.AZKH_0334	5.13e-58	204.0	COG3245@1|root,COG3245@2|Bacteria,1RG2V@1224|Proteobacteria,2VS0Q@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS2_k127_5484096_34	864051.BurJ1DRAFT_4166	4.496e-16	92.0	2CBTM@1|root,32RU1@2|Bacteria,1N3GE@1224|Proteobacteria,2VURB@28216|Betaproteobacteria,1KNM9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5484096_20	864051.BurJ1DRAFT_4165	3.518e-68	245.0	COG0760@1|root,COG0760@2|Bacteria,1RGNX@1224|Proteobacteria,2VRQU@28216|Betaproteobacteria,1KNFK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N_3
CMS2_k127_5484096_25	395495.Lcho_4134	1.102e-54	202.0	COG3303@1|root,COG3303@2|Bacteria,1RG2D@1224|Proteobacteria,2VRXP@28216|Betaproteobacteria,1KNJI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS2_k127_5484096_0	713586.KB900536_gene2217	0.0	1244.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS2_k127_5490205_17	1163617.SCD_n02272	4.121e-87	300.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKVT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS2_k127_5490205_16	580332.Slit_1670	4.32e-93	316.0	COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,2W0RY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5490205_4	631362.Thi970DRAFT_04939	2.128e-233	730.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS2_k127_5490205_19	1396858.Q666_04550	4.132e-69	237.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,466Q5@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS2_k127_5490205_9	765912.Thimo_0344	1.443e-137	447.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales	135613|Chromatiales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS2_k127_5490205_15	911239.CF149_07399	2.468e-95	317.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS2_k127_5490205_6	472759.Nhal_2813	1.639e-169	539.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS2_k127_5490205_20	754477.Q7C_902	6.962e-66	228.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,460J0@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS2_k127_5490205_25	1049564.TevJSym_ad00710	2.152e-50	186.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1J67T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS2_k127_5490205_14	572477.Alvin_1766	2.105e-95	323.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1WW48@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS2_k127_5490205_21	1027273.GZ77_21505	2.132e-64	225.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1XJWN@135619|Oceanospirillales	135619|Oceanospirillales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CMS2_k127_5490205_10	1049564.TevJSym_ad00750	6.678e-132	425.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1J9IK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
CMS2_k127_5490205_24	472759.Nhal_2797	4.838e-53	190.0	COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria,1WZ30@135613|Chromatiales	135613|Chromatiales	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS2_k127_5490205_1	395493.BegalDRAFT_1618	9.313e-291	903.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,4608E@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS2_k127_5490205_11	765914.ThisiDRAFT_0858	1.235e-112	372.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales	135613|Chromatiales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS2_k127_5490205_27	314278.NB231_00860	1.694e-19	90.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1WZRT@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS2_k127_5490205_26	653733.Selin_1077	2.802e-24	112.0	2EEP1@1|root,338GU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5490205_7	396588.Tgr7_0882	3.475e-164	528.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1WWHC@135613|Chromatiales	135613|Chromatiales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
CMS2_k127_5490205_23	29495.EA26_18215	8.649e-54	195.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1XVS1@135623|Vibrionales	135623|Vibrionales	H	COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS2_k127_5490205_18	396588.Tgr7_0880	6.863e-86	288.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1X2ET@135613|Chromatiales	135613|Chromatiales	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
CMS2_k127_5490205_12	1026882.MAMP_01827	1.071e-107	355.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,4609A@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS2_k127_5490205_13	572477.Alvin_2756	1.312e-100	336.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS2_k127_5490205_22	243233.MCA2316	1.926e-58	204.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,1XFAU@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS2_k127_5490205_28	314345.SPV1_10651	2.777e-16	80.0	2EIC1@1|root,33C3D@2|Bacteria,1NHMH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
CMS2_k127_5490205_0	1163617.SCD_n02039	0.0	1213.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS2_k127_5490205_5	686340.Metal_1390	2.584e-176	564.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XEKR@135618|Methylococcales	135618|Methylococcales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS2_k127_5490205_8	396588.Tgr7_0873	1.828e-139	449.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1WXUD@135613|Chromatiales	135613|Chromatiales	G	6-phosphogluconate dehydrogenase	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS2_k127_5490205_3	396588.Tgr7_0872	3.131e-240	750.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1WX93@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS2_k127_5490205_2	1303518.CCALI_00158	3.545e-274	853.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcSMS35_1347.EcSMS35_4486	PGI
CMS2_k127_5696118_2	472759.Nhal_0412	7.614e-229	714.0	COG0247@1|root,COG0277@1|root,COG0437@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0437@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales	135613|Chromatiales	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
CMS2_k127_5696118_13	1415754.JQMK01000013_gene113	1.292e-57	207.0	COG3193@1|root,COG3193@2|Bacteria,1PP2V@1224|Proteobacteria,1T9W2@1236|Gammaproteobacteria,46BWH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
CMS2_k127_5696118_19	1255043.TVNIR_1937	1.111e-21	95.0	2E3CN@1|root,32YBX@2|Bacteria,1N716@1224|Proteobacteria,1SEFN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5696118_11	1122201.AUAZ01000006_gene3896	5.554e-102	335.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,46422@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS2_k127_5696118_1	1255043.TVNIR_1040	2.995e-234	734.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS2_k127_5696118_12	519989.ECTPHS_02706	6.399e-60	216.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1WYDB@135613|Chromatiales	135613|Chromatiales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS2_k127_5696118_18	768671.ThimaDRAFT_1415	1.099e-22	101.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1WZ69@135613|Chromatiales	135613|Chromatiales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS2_k127_5696118_20	1049564.TevJSym_ak00980	3.026e-12	70.0	2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,1J7DD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM TIGR02449 family protein	VL23_04670	-	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	-
CMS2_k127_5696118_16	396588.Tgr7_2765	2.607e-39	153.0	COG3079@1|root,COG3079@2|Bacteria	2|Bacteria	S	Belongs to the UPF0149 family	ygfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
CMS2_k127_5696118_4	713586.KB900536_gene2596	1.277e-203	642.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS2_k127_5696118_9	472759.Nhal_3717	4.235e-115	385.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales	135613|Chromatiales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS2_k127_5696118_7	1049564.TevJSym_ao00020	6.751e-134	437.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1J4IU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	visC	-	-	ko:K03184,ko:K03185,ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R04989,R06146,R08768,R08773,R08775	RC00046,RC01254,RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3,SE
CMS2_k127_5696118_5	870187.Thini_2540	1.362e-157	507.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,460KI@72273|Thiotrichales	72273|Thiotrichales	P	Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085)	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS2_k127_5696118_8	1123368.AUIS01000018_gene743	1.69e-115	381.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,2NCGB@225057|Acidithiobacillales	1236|Gammaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS2_k127_5696118_6	1453501.JELR01000002_gene689	2.959e-146	472.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,464MN@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_2953	GCV_T,GCV_T_C
CMS2_k127_5696118_14	392500.Swoo_3968	1.941e-55	196.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,2QBKB@267890|Shewanellaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iE2348C_1286.E2348C_3156,iPC815.YPO0906	GCV_H
CMS2_k127_5696118_3	1123368.AUIS01000018_gene740	2.632e-205	647.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,2NCEB@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the GcvP family	-	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
CMS2_k127_5696118_10	396588.Tgr7_1819	2.926e-114	376.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1WYG8@135613|Chromatiales	135613|Chromatiales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_5696118_0	396588.Tgr7_2755	5.875e-240	749.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
CMS2_k127_5696118_15	1123367.C666_07715	1.575e-39	151.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS2_k127_5696118_17	317025.Tcr_0235	3.522e-25	113.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria,462MH@72273|Thiotrichales	72273|Thiotrichales	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5771951_21	395961.Cyan7425_4419	2.696e-59	215.0	COG2204@1|root,COG3852@1|root,COG2204@2|Bacteria,COG3852@2|Bacteria,1GQZY@1117|Cyanobacteria	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS2_k127_5771951_1	1049564.TevJSym_aw00620	1.002e-308	951.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1J503@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS2_k127_5771951_13	395493.BegalDRAFT_0273	1.057e-111	367.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,1RQKK@1236|Gammaproteobacteria,460FV@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
CMS2_k127_5771951_3	580332.Slit_1196	3.072e-303	949.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CMS2_k127_5771951_9	396588.Tgr7_1499	4.813e-130	445.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
CMS2_k127_5771951_8	1430440.MGMSRv2_1032	6.545e-146	477.0	COG5424@1|root,COG5424@2|Bacteria,1NM66@1224|Proteobacteria,2UR4P@28211|Alphaproteobacteria,2JV56@204441|Rhodospirillales	204441|Rhodospirillales	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5771951_2	768671.ThimaDRAFT_4579	1.512e-304	942.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1WXJT@135613|Chromatiales	135613|Chromatiales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
CMS2_k127_5771951_29	519989.ECTPHS_10014	2.756e-29	124.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
CMS2_k127_5771951_30	1158146.KB907123_gene767	4.68e-22	97.0	COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1WZKP@135613|Chromatiales	135613|Chromatiales	S	YcgL domain	-	-	-	ko:K09902	-	-	-	-	ko00000	-	-	-	YcgL
CMS2_k127_5771951_5	765913.ThidrDRAFT_2318	1.054e-175	561.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1WW5K@135613|Chromatiales	135613|Chromatiales	E	phosphoserine phosphatase SerB	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
CMS2_k127_5771951_4	1163617.SCD_n01692	2.072e-191	604.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CMS2_k127_5771951_15	247633.GP2143_04710	5.414e-108	356.0	2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1J5GW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2797)	LA2027	-	-	-	-	-	-	-	-	-	-	-	DUF2797
CMS2_k127_5771951_28	349124.Hhal_1785	2.188e-36	147.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,1RYAA@1236|Gammaproteobacteria,1WXSC@135613|Chromatiales	135613|Chromatiales	S	PFAM Pentapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS2_k127_5771951_19	225937.HP15_796	1.64e-71	258.0	COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1R46H@1224|Proteobacteria,1S1DF@1236|Gammaproteobacteria,46CHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,tRNA_edit
CMS2_k127_5771951_14	344747.PM8797T_23971	2.536e-110	370.0	COG0389@1|root,COG0389@2|Bacteria,2IZ2I@203682|Planctomycetes	203682|Planctomycetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS2_k127_5771951_18	748658.KB907321_gene848	1.486e-82	276.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,1RRGB@1236|Gammaproteobacteria,1X08N@135613|Chromatiales	135613|Chromatiales	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS2_k127_5771951_7	631362.Thi970DRAFT_01815	7.066e-160	517.0	COG0702@1|root,COG0702@2|Bacteria,1MZ0C@1224|Proteobacteria,1S2PQ@1236|Gammaproteobacteria,1WZW0@135613|Chromatiales	135613|Chromatiales	GM	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3,NAD_binding_10
CMS2_k127_5771951_22	1042375.AFPL01000046_gene1838	3.233e-59	210.0	COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria,1S5XB@1236|Gammaproteobacteria,46BNY@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
CMS2_k127_5771951_25	1157708.KB907456_gene2216	5.168e-47	176.0	29Q66@1|root,30B54@2|Bacteria,1N9YZ@1224|Proteobacteria,2VUIM@28216|Betaproteobacteria,4AHAV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
CMS2_k127_5771951_10	857087.Metme_2101	2.148e-128	426.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XFHJ@135618|Methylococcales	135618|Methylococcales	K	Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
CMS2_k127_5771951_17	215803.DB30_5754	3.271e-90	307.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS2_k127_5771951_27	765913.ThidrDRAFT_0627	2.172e-42	165.0	COG0500@1|root,COG2226@2|Bacteria,1N3VV@1224|Proteobacteria,1SCTZ@1236|Gammaproteobacteria,1WZXH@135613|Chromatiales	135613|Chromatiales	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5771951_20	1192868.CAIU01000033_gene4184	2.255e-59	212.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VFYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_5771951_0	390235.PputW619_4967	0.0	1052.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1YWD9@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	SMART Resolvase, RNase H domain protein fold	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CMS2_k127_5771951_6	2340.JV46_07900	1.235e-162	518.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,1J7N5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574	AIRS,AIRS_C
CMS2_k127_5771951_11	2340.JV46_07910	2.071e-121	403.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,1J816@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
CMS2_k127_5771951_23	314278.NB231_13161	3.63e-54	203.0	COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,1WZAC@135613|Chromatiales	135613|Chromatiales	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
CMS2_k127_5771951_16	472759.Nhal_1250	2.953e-92	310.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,1S31N@1236|Gammaproteobacteria,1WXP2@135613|Chromatiales	135613|Chromatiales	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS2_k127_5771951_26	396588.Tgr7_1818	1.627e-46	177.0	COG3221@1|root,COG3221@2|Bacteria,1NBWA@1224|Proteobacteria,1TKA1@1236|Gammaproteobacteria,1X0ZP@135613|Chromatiales	135613|Chromatiales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS2_k127_5771951_12	265072.Mfla_0887	3.48e-115	373.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KKQX@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CMS2_k127_5778085_16	497321.C664_17867	7.793e-22	97.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	pilA	-	-	ko:K02650,ko:K02682	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
CMS2_k127_5778085_11	396588.Tgr7_0224	3.538e-52	196.0	COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1X1I0@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein C	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
CMS2_k127_5778085_2	1049564.TevJSym_av00360	1.085e-197	637.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4UY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein D	xcsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS2_k127_5778085_1	765914.ThisiDRAFT_1295	6.363e-215	677.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS2_k127_5778085_5	519989.ECTPHS_04329	7.16e-159	510.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS2_k127_5778085_9	519989.ECTPHS_04324	9.271e-65	223.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1WY8U@135613|Chromatiales	135613|Chromatiales	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS2_k127_5778085_17	523791.Kkor_2312	1.006e-18	93.0	COG4970@1|root,COG4970@2|Bacteria,1QXFS@1224|Proteobacteria,1T3AT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	general secretion pathway protein h	gspH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CMS2_k127_5778085_15	395493.BegalDRAFT_2131	5.746e-25	110.0	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria	1224|Proteobacteria	NU	General secretion pathway protein I	gspI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
CMS2_k127_5778085_12	395493.BegalDRAFT_2659	9.673e-44	168.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,462G2@72273|Thiotrichales	72273|Thiotrichales	U	General secretion pathway protein J	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CMS2_k127_5778085_8	395493.BegalDRAFT_3088	6.345e-70	250.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,460PF@72273|Thiotrichales	72273|Thiotrichales	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS2_k127_5778085_10	395493.BegalDRAFT_2442	2.407e-52	200.0	COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,462ER@72273|Thiotrichales	72273|Thiotrichales	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	-	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
CMS2_k127_5778085_14	765914.ThisiDRAFT_1847	2.357e-27	119.0	COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1SCSU@1236|Gammaproteobacteria,1WZQA@135613|Chromatiales	135613|Chromatiales	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
CMS2_k127_5778085_13	519989.ECTPHS_04289	3.164e-35	145.0	2CBG9@1|root,32RTB@2|Bacteria,1R86M@1224|Proteobacteria,1RNNN@1236|Gammaproteobacteria,1X1MQ@135613|Chromatiales	135613|Chromatiales	S	type II secretion system protein N	-	-	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
CMS2_k127_5778085_3	216142.LT40_19830	1.328e-169	544.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02481,ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS2_k127_5778085_7	472759.Nhal_0597	2.722e-120	405.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
CMS2_k127_5778085_19	223283.PSPTO_0825	3.359e-11	67.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,1SGHN@1236|Gammaproteobacteria,1Z84G@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
CMS2_k127_5778085_4	713586.KB900536_gene1350	9.499e-160	514.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales	135613|Chromatiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS2_k127_5778085_6	1123261.AXDW01000017_gene3201	2.059e-144	467.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1X36R@135614|Xanthomonadales	135614|Xanthomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS2_k127_5778085_0	243233.MCA0969	6.239e-223	704.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1XDUX@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS2_k127_5778085_20	220664.PFL_1174	1.232e-06	50.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1YMTE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
CMS2_k127_5876512_1	1232410.KI421415_gene3042	3.363e-73	251.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2WMW2@28221|Deltaproteobacteria,43TS9@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
CMS2_k127_5876512_2	443144.GM21_0922	3.011e-60	215.0	COG3932@1|root,COG3932@2|Bacteria,1N0FN@1224|Proteobacteria	1224|Proteobacteria	S	ABC-type transport system, permease components	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
CMS2_k127_5876512_5	99598.Cal7507_5772	2.493e-08	65.0	2EPY9@1|root,33HIV@2|Bacteria,1G8GC@1117|Cyanobacteria,1HK47@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_5876512_3	187272.Mlg_2077	1.374e-50	194.0	COG2199@1|root,COG3706@2|Bacteria,1N7HG@1224|Proteobacteria,1S2NP@1236|Gammaproteobacteria,1X2AA@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS2_k127_6110211_1	1249627.D779_1807	2.821e-214	671.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1WX93@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS2_k127_6110211_2	1123392.AQWL01000007_gene1006	9.741e-202	634.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1RFYF@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS2_k127_6110211_8	1391646.AVSU01000016_gene3190	1.919e-62	223.0	COG1388@1|root,COG1388@2|Bacteria,1V5F7@1239|Firmicutes,25BMI@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6110211_5	1121374.KB891590_gene1663	3.411e-110	368.0	COG2960@1|root,COG2960@2|Bacteria,1NJYD@1224|Proteobacteria,1RYI7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6110211_12	1046724.KB889923_gene1409	3.76e-21	96.0	COG2010@1|root,COG2010@2|Bacteria,1RFJV@1224|Proteobacteria,1S4GY@1236|Gammaproteobacteria,46905@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_6110211_10	1122134.KB893650_gene1574	4.233e-30	123.0	COG2010@1|root,COG2010@2|Bacteria,1RFJV@1224|Proteobacteria,1S4GY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_6110211_3	713586.KB900536_gene2754	3.882e-159	506.0	COG3391@1|root,COG3391@2|Bacteria,1RF7X@1224|Proteobacteria	1224|Proteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	mxaE	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,NHL
CMS2_k127_6110211_11	1163617.SCD_n02242	7.301e-22	96.0	COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,2VY74@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS2_k127_6110211_4	1163617.SCD_n02240	3.843e-119	388.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VQEJ@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
CMS2_k127_6110211_0	1163617.SCD_n02239	0.0	1184.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
CMS2_k127_6110211_6	1280953.HOC_18991	2.035e-107	360.0	COG0644@1|root,COG0644@2|Bacteria,1R4JF@1224|Proteobacteria,2U0P0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0644 Dehydrogenases (flavoproteins)	-	-	-	-	-	-	-	-	-	-	-	-	HI0933_like,NAD_binding_8
CMS2_k127_6110211_7	765911.Thivi_0865	5.015e-102	340.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,1RNS3@1236|Gammaproteobacteria,1WY2Y@135613|Chromatiales	135613|Chromatiales	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS2_k127_6110211_9	1504981.KO116_2254	1.857e-58	208.0	COG0398@1|root,COG0398@2|Bacteria,1RDZ2@1224|Proteobacteria,1S94Z@1236|Gammaproteobacteria,1XMN0@135619|Oceanospirillales	135619|Oceanospirillales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS2_k127_6214444_1	317025.Tcr_1061	3.505e-87	293.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,4609H@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
CMS2_k127_6214444_3	1123393.KB891326_gene37	1.099e-29	125.0	COG3678@1|root,COG3678@2|Bacteria,1QC6V@1224|Proteobacteria,2WCBH@28216|Betaproteobacteria,1KTDB@119069|Hydrogenophilales	119069|Hydrogenophilales	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6214444_0	1121939.L861_14915	3.528e-131	423.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XKHR@135619|Oceanospirillales	135619|Oceanospirillales	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
CMS2_k127_6214444_2	1283300.ATXB01000001_gene1694	8.792e-80	268.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria,1XFZ1@135618|Methylococcales	135618|Methylococcales	C	ATP synthase alpha/beta chain, C terminal domain	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS2_k127_621541_7	1120953.AUBH01000014_gene2488	2.291e-120	398.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,464WJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS2_k127_621541_1	1049564.TevJSym_an00610	1.221e-238	752.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1J4DW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
CMS2_k127_621541_8	395493.BegalDRAFT_3486	9.565e-33	130.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,4613V@72273|Thiotrichales	72273|Thiotrichales	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS2_k127_621541_4	1122134.KB893651_gene2401	4.785e-198	623.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1XHH8@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS2_k127_621541_6	1121921.KB898708_gene1318	3.166e-144	466.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,2PMHE@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Queuosine biosynthesis protein	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS2_k127_621541_5	396588.Tgr7_2071	8.91e-181	578.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1WWBR@135613|Chromatiales	135613|Chromatiales	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
CMS2_k127_621541_2	396588.Tgr7_2072	5.788e-223	705.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,1X0BN@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
CMS2_k127_621541_3	1266914.ATUK01000017_gene584	2.949e-206	649.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS2_k127_621541_0	243233.MCA1475	1.196e-320	995.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS2_k127_6226118_1	472759.Nhal_2115	1.081e-56	203.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS2_k127_6226118_3	76114.ebA5350	1.182e-49	185.0	COG2823@1|root,COG2823@2|Bacteria,1RFX5@1224|Proteobacteria,2VRR5@28216|Betaproteobacteria,2KY5G@206389|Rhodocyclales	206389|Rhodocyclales	S	BON domain	osmY	-	-	-	-	-	-	-	-	-	-	-	BON
CMS2_k127_6226118_0	1123368.AUIS01000029_gene1289	2.792e-275	859.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,2NBWK@225057|Acidithiobacillales	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS2_k127_6226118_2	472759.Nhal_1889	2.053e-54	201.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,1T0ZH@1236|Gammaproteobacteria,1X0TI@135613|Chromatiales	135613|Chromatiales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS2_k127_6232533_27	472759.Nhal_3800	2.59e-12	71.0	COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SDGD@1236|Gammaproteobacteria,1X2GY@135613|Chromatiales	135613|Chromatiales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6232533_17	1026882.MAMP_01564	1.138e-73	253.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions	slmA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
CMS2_k127_6232533_8	1168067.JAGP01000001_gene1845	2.201e-145	465.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,46006@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS2_k127_6232533_3	105559.Nwat_3050	5.973e-183	583.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1WXCY@135613|Chromatiales	135613|Chromatiales	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS2_k127_6232533_15	2340.JV46_16850	2.765e-75	254.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,1J60J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS2_k127_6232533_9	998088.B565_3906	9.169e-143	463.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1Y3V3@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS2_k127_6232533_13	519989.ECTPHS_00999	9.876e-101	335.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1WXFP@135613|Chromatiales	135613|Chromatiales	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS2_k127_6232533_22	396588.Tgr7_0325	1.885e-39	148.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1WYZ3@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS2_k127_6232533_25	1266914.ATUK01000012_gene139	2.658e-26	108.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1WZA6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS2_k127_6232533_7	768671.ThimaDRAFT_3070	1.107e-145	472.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria,1WVUQ@135613|Chromatiales	135613|Chromatiales	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
CMS2_k127_6232533_1	765913.ThidrDRAFT_2125	5.62e-246	778.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales	135613|Chromatiales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS2_k127_6232533_12	472759.Nhal_0558	4.357e-132	428.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1WY5A@135613|Chromatiales	135613|Chromatiales	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_6232533_14	243233.MCA3077	9.749e-85	288.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1XDJA@135618|Methylococcales	135618|Methylococcales	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS2_k127_6232533_6	472759.Nhal_0556	2.929e-148	482.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1WX3X@135613|Chromatiales	135613|Chromatiales	N	PFAM ABC-type uncharacterised transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS2_k127_6232533_19	243233.MCA3075	1.225e-47	181.0	2E2KI@1|root,32XPU@2|Bacteria,1RH64@1224|Proteobacteria,1RYC7@1236|Gammaproteobacteria,1XGH6@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS2_k127_6232533_10	472759.Nhal_2152	5.467e-136	443.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1X25G@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS2_k127_6232533_5	472759.Nhal_2153	2.622e-156	499.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1WXRY@135613|Chromatiales	135613|Chromatiales	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_6232533_11	472759.Nhal_2154	2.261e-132	438.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	1236|Gammaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS2_k127_6232533_4	1121939.L861_03570	2.314e-166	537.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0019438,GO:0019464,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS2_k127_6232533_20	1123508.JH636443_gene5018	8.268e-46	170.0	COG3324@1|root,COG3324@2|Bacteria,2J3W8@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
CMS2_k127_6232533_0	380394.Lferr_0167	5.908e-271	850.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1S1ID@1236|Gammaproteobacteria,2NC8Z@225057|Acidithiobacillales	225057|Acidithiobacillales	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
CMS2_k127_6232533_18	314345.SPV1_01487	2.954e-50	189.0	293CN@1|root,2ZQV6@2|Bacteria,1RDZB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6232533_24	28229.ND2E_2955	1.599e-28	132.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Cytochrome c	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS2_k127_6232533_26	998674.ATTE01000001_gene164	4.637e-18	98.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,460ST@72273|Thiotrichales	72273|Thiotrichales	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS2_k127_6232533_16	426114.THI_3654	9.288e-74	258.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS2_k127_6232533_21	1207063.P24_00120	1.411e-41	163.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,2JS06@204441|Rhodospirillales	204441|Rhodospirillales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
CMS2_k127_6232533_23	1120963.KB894492_gene1635	3.31e-30	125.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,2Q2FS@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	COG3245 Cytochrome c5	cyc	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	Cytochrome_CBB3
CMS2_k127_6232533_2	1049564.TevJSym_ae00910	2.592e-190	600.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1J4TF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS2_k127_6232533_28	1123392.AQWL01000008_gene1249	7.674e-08	53.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VN77@28216|Betaproteobacteria,1KS6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS2_k127_6238390_0	903818.KI912268_gene1381	6.278e-120	399.0	COG3863@1|root,COG3863@2|Bacteria	2|Bacteria	T	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CMS2_k127_6238390_1	296587.XP_002499809.1	1.215e-92	328.0	2E3BA@1|root,2SAF2@2759|Eukaryota,3822D@33090|Viridiplantae,34NGR@3041|Chlorophyta	2759|Eukaryota	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS2_k127_6254339_43	1049564.TevJSym_ap00260	3.958e-21	95.0	COG0637@1|root,COG1234@1|root,COG0637@2|Bacteria,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,1RRV8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	CLP1_P,Lactamase_B,Lactamase_B_2
CMS2_k127_6254339_0	765910.MARPU_14615	0.0	1105.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1WW8W@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS2_k127_6254339_29	1249627.D779_1951	2.964e-64	227.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S9PP@1236|Gammaproteobacteria,1WWV8@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS2_k127_6254339_8	765911.Thivi_0246	7.362e-197	631.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1WVWQ@135613|Chromatiales	135613|Chromatiales	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C
CMS2_k127_6254339_1	273121.WS0601	2.193e-305	944.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2YRFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS2_k127_6254339_38	273121.WS0602	1.184e-37	142.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,42VFF@68525|delta/epsilon subdivisions,2YQ8P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
CMS2_k127_6254339_5	713586.KB900536_gene3079	1.128e-239	756.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1WX1A@135613|Chromatiales	135613|Chromatiales	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
CMS2_k127_6254339_39	580332.Slit_0143	2.829e-32	128.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rhodanese domain protein	pspE2	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS2_k127_6254339_7	1123368.AUIS01000023_gene933	4.021e-203	670.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
CMS2_k127_6254339_25	305700.B447_15236	5.729e-74	258.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VQY7@28216|Betaproteobacteria,2KYP5@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS2_k127_6254339_44	105559.Nwat_0401	8.836e-21	93.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,1SFVY@1236|Gammaproteobacteria,1X1TN@135613|Chromatiales	135613|Chromatiales	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS2_k127_6254339_16	472759.Nhal_0594	2.845e-115	376.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales	135613|Chromatiales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS2_k127_6254339_23	472759.Nhal_1927	1.252e-80	275.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1WVWE@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS2_k127_6254339_17	1123401.JHYQ01000027_gene3134	4.142e-114	374.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,4608T@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Serine O-acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS2_k127_6254339_30	1177154.Y5S_00666	7.202e-62	216.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XJI3@135619|Oceanospirillales	135619|Oceanospirillales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
CMS2_k127_6254339_15	472759.Nhal_1930	5.576e-128	421.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1WWHG@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS2_k127_6254339_6	1049564.TevJSym_au00120	1.702e-208	653.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1J4KY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	iPC815.YPO2896,iYL1228.KPN_02862	Aminotran_5
CMS2_k127_6254339_28	887327.HMPREF0476_1517	1.369e-66	228.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,2KQX6@206351|Neisseriales	206351|Neisseriales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS2_k127_6254339_32	1165096.ARWF01000001_gene791	8.557e-51	184.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,2KMUB@206350|Nitrosomonadales	206350|Nitrosomonadales	S	TIGRFAM iron-sulfur cluster assembly protein IscA	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS2_k127_6254339_33	1049564.TevJSym_au00150	1.197e-44	168.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1J6NP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
CMS2_k127_6254339_3	1049564.TevJSym_au00160	1.141e-281	877.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CMS2_k127_6254339_31	1232683.ADIMK_1319	3.546e-59	206.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,4674E@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS2_k127_6254339_40	1123368.AUIS01000004_gene258	4.711e-29	117.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,2NDAS@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Iron-sulphur cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
CMS2_k127_6254339_26	519989.ECTPHS_12838	3.035e-73	249.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1WYAE@135613|Chromatiales	135613|Chromatiales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS2_k127_6254339_13	1122201.AUAZ01000021_gene3211	6.059e-147	475.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,46420@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS2_k127_6254339_35	105559.Nwat_0768	2.92e-43	168.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS2_k127_6254339_41	1049564.TevJSym_ac01930	8.031e-27	122.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1J77Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4115)	rodZ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CMS2_k127_6254339_11	1288826.MSNKSG1_05011	1.471e-182	576.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,464MT@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037	GcpE
CMS2_k127_6254339_10	290398.Csal_2855	3.459e-185	587.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XIK3@135619|Oceanospirillales	135619|Oceanospirillales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS2_k127_6254339_37	1049564.TevJSym_ac01910	2.029e-39	154.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1J6AW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yfgM	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552	-	-	-	-	-	-	-	-	-	-	TPR_21
CMS2_k127_6254339_22	472759.Nhal_2465	4.198e-86	299.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1WWQT@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS2_k127_6254339_9	396588.Tgr7_2045	1.588e-195	620.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales	135613|Chromatiales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS2_k127_6254339_42	340177.Cag_0883	7.29e-24	102.0	COG0607@1|root,32YCZ@2|Bacteria	2|Bacteria	P	Sulfurtransferase	ygaP	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS2_k127_6254339_27	1255043.TVNIR_1302	3.819e-72	246.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1WZ2F@135613|Chromatiales	135613|Chromatiales	O	PFAM peptidylprolyl isomerase FKBP-type	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS2_k127_6254339_20	523791.Kkor_0261	1.212e-92	315.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RZ5E@1236|Gammaproteobacteria,1XH3B@135619|Oceanospirillales	135619|Oceanospirillales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS2_k127_6254339_19	1128912.GMES_2334	1.207e-92	319.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,466B6@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CMS2_k127_6254339_34	1085623.GNIT_1530	8.076e-44	165.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,46CH1@72275|Alteromonadaceae	1236|Gammaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_6254339_24	1151127.KB906328_gene2350	1.019e-78	272.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,1YNT3@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS2_k127_6254339_12	314278.NB231_00455	2.246e-149	485.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS2_k127_6254339_47	768671.ThimaDRAFT_4576	1.26e-06	54.0	2AS0D@1|root,31HCK@2|Bacteria,1RH91@1224|Proteobacteria,1S6TH@1236|Gammaproteobacteria,1WYHI@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6254339_4	1286106.MPL1_03293	1.088e-243	761.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,45ZZA@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
CMS2_k127_6254339_18	765910.MARPU_04010	2.705e-101	340.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1X2T9@135613|Chromatiales	135613|Chromatiales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
CMS2_k127_6254339_21	398579.Spea_2368	2.98e-86	291.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,2Q8YK@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
CMS2_k127_6254339_14	1049564.TevJSym_an00090	2.013e-140	450.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,1J5AI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
CMS2_k127_6254339_2	391615.ABSJ01000002_gene527	4.197e-289	893.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1J4G5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
CMS2_k127_6254339_36	1266914.ATUK01000016_gene459	5.569e-41	158.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1WXFY@135613|Chromatiales	135613|Chromatiales	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
CMS2_k127_6331068_12	1232683.ADIMK_2963	7.048e-129	415.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RP7F@1236|Gammaproteobacteria,4658Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	oxidase, subunit	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iPC815.YPO1118	Cyt_bd_oxida_II
CMS2_k127_6331068_1	301.JNHE01000012_gene1353	1.613e-269	837.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1YEMC@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Cytochrome bd terminal oxidase subunit I	cydA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iPC815.YPO1117,iSFxv_1172.SFxv_0621,iS_1188.S0577	Cyt_bd_oxida_I
CMS2_k127_6331068_10	396588.Tgr7_0682	6.27e-158	510.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RM90@1236|Gammaproteobacteria,1WXYA@135613|Chromatiales	135613|Chromatiales	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
CMS2_k127_6331068_6	228410.NE1247	2.113e-210	662.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2VH4U@28216|Betaproteobacteria,373X0@32003|Nitrosomonadales	28216|Betaproteobacteria	E	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
CMS2_k127_6331068_3	1535422.ND16A_2625	1.542e-225	710.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,1RR3N@1236|Gammaproteobacteria,2Q81G@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Cytochrome D1 heme domain	nirN	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Cytochrome_CBB3
CMS2_k127_6331068_8	1163617.SCD_n00376	3.693e-190	601.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	nirJ	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS2_k127_6331068_18	1049564.TevJSym_bo00110	5.363e-68	236.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,1S7GD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Nitrite reductase heme biosynthesis H protein	nirH	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
CMS2_k127_6331068_20	1049564.TevJSym_bo00130	2.235e-58	208.0	COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,1S8HH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	heme biosynthesis protein	nirG	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
CMS2_k127_6331068_19	1255043.TVNIR_1645	1.738e-59	211.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,1S620@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1522 Transcriptional regulators	nirL	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
CMS2_k127_6331068_21	1163617.SCD_n00373	4.08e-44	168.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2VHP8@28216|Betaproteobacteria	28216|Betaproteobacteria	K	COG1522 Transcriptional regulators	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
CMS2_k127_6331068_9	1163617.SCD_n00372	1.535e-176	562.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2VH1W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cytochrome d1, heme region	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
CMS2_k127_6331068_25	697282.Mettu_3241	6.85e-29	121.0	COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,1SFGZ@1236|Gammaproteobacteria,1XFNP@135618|Methylococcales	135618|Methylococcales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K19344	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
CMS2_k127_6331068_14	1316936.K678_05968	1.486e-87	296.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,2JQIR@204441|Rhodospirillales	204441|Rhodospirillales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS2_k127_6331068_0	292415.Tbd_0077	2.483e-286	887.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,1KS6X@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome D1 heme domain	-	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
CMS2_k127_6331068_5	1123368.AUIS01000008_gene2145	3.437e-217	690.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM von Willebrand factor type A	norD	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
CMS2_k127_6331068_13	2340.JV46_05470	8.078e-121	397.0	COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,1RZ0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
CMS2_k127_6331068_11	1049564.TevJSym_bg00290	3.227e-129	420.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1J7ZN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CbbQ/NirQ/NorQ C-terminal	nirQ	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
CMS2_k127_6331068_30	1123368.AUIS01000008_gene2149	8.132e-15	77.0	2BKCK@1|root,32ET5@2|Bacteria,1NI55@1224|Proteobacteria,1SVED@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
CMS2_k127_6331068_16	1049564.TevJSym_bg00310	1.79e-78	268.0	COG1845@1|root,COG1845@2|Bacteria,1RG3S@1224|Proteobacteria,1S75W@1236|Gammaproteobacteria,1JADH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c oxidase subunit III	nirO	-	1.9.3.1	ko:K02164,ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081,R00294	RC00016,RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10,3.D.4.4,3.D.4.6	-	-	COX3
CMS2_k127_6331068_2	1278309.KB907109_gene3271	6.854e-261	809.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1XIMZ@135619|Oceanospirillales	135619|Oceanospirillales	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
CMS2_k127_6331068_17	1278309.KB907109_gene3270	4.308e-70	240.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,1S4BC@1236|Gammaproteobacteria,1XKAN@135619|Oceanospirillales	135619|Oceanospirillales	C	Cytochrome c	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
CMS2_k127_6331068_15	754477.Q7C_857	3.093e-85	297.0	28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,462BI@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF3549)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3549
CMS2_k127_6331068_27	314345.SPV1_12225	5.08e-23	104.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	-	-	3.6.4.12,3.6.4.13	ko:K03655,ko:K05592	ko03018,ko03440,map03018,map03440	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03400	-	-	-	DbpA,RRM_1
CMS2_k127_6331068_26	768671.ThimaDRAFT_3392	1.759e-28	120.0	28QMK@1|root,2ZD39@2|Bacteria,1RAWM@1224|Proteobacteria,1S2FU@1236|Gammaproteobacteria,1WY0Y@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6331068_23	631362.Thi970DRAFT_04216	3.079e-35	138.0	2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,1S97C@1236|Gammaproteobacteria,1X0UY@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6331068_7	1123368.AUIS01000009_gene2460	9.322e-208	656.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,2NCDY@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
CMS2_k127_6331068_22	1163617.SCD_n02061	9.226e-42	157.0	2E2DR@1|root,32XIE@2|Bacteria,1N271@1224|Proteobacteria,2W4PR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
CMS2_k127_6331068_28	998674.ATTE01000001_gene2563	2.646e-19	99.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,461AV@72273|Thiotrichales	72273|Thiotrichales	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS2_k127_6331068_24	272134.KB731324_gene1337	5.912e-29	128.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS2_k127_6331068_29	227086.JGI_V11_43966	2.031e-18	91.0	COG0790@1|root,KOG1550@2759|Eukaryota	227086.JGI_V11_43966|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6331068_4	1122201.AUAZ01000020_gene2660	2.717e-221	694.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,46493@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	membrane GTPase involved in stress response	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS2_k127_6376198_2	1313172.YM304_34520	1.802e-137	448.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
CMS2_k127_6376198_3	927677.ALVU02000001_gene3056	9.084e-23	111.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Beta_helix,DUF1573,DUF4861,Pec_lyase_C,Pectinesterase
CMS2_k127_6376198_0	1313172.YM304_03090	8.831e-190	608.0	COG0737@1|root,COG0737@2|Bacteria,2I7X6@201174|Actinobacteria,4CP5J@84992|Acidimicrobiia	2|Bacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CMS2_k127_6376198_1	710696.Intca_0183	2.885e-165	532.0	COG4222@1|root,COG4222@2|Bacteria,2GJN8@201174|Actinobacteria,4FF9Q@85021|Intrasporangiaceae	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS2_k127_6439163_3	671143.DAMO_2439	2.459e-18	93.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS2_k127_6439163_5	1151118.KB895785_gene2660	1.158e-05	59.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,1W835@1268|Micrococcaceae	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
CMS2_k127_6439163_1	671143.DAMO_2415	2.459e-158	525.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	nirS	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C,Cytochrom_D1,Cytochrome_CBB3,GSDH
CMS2_k127_6439163_0	870187.Thini_0139	7.492e-220	691.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,1RPYD@1236|Gammaproteobacteria,45ZVB@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
CMS2_k127_6439163_2	768671.ThimaDRAFT_0180	3.044e-103	342.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,1WXIM@135613|Chromatiales	135613|Chromatiales	P	PFAM Ion transport	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
CMS2_k127_6439163_4	579405.Dd703_2352	1.216e-06	50.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,2JDK7@204037|Dickeya	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_6462848_6	1123393.KB891327_gene360	1.77e-19	96.0	COG0695@1|root,COG0695@2|Bacteria,1PWSH@1224|Proteobacteria,2WCB4@28216|Betaproteobacteria,1KTCN@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS2_k127_6462848_3	1207063.P24_04989	4.185e-114	380.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,2JQ7C@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS2_k127_6462848_7	580332.Slit_2973	1.002e-18	86.0	2DR87@1|root,33AMS@2|Bacteria,1NJ06@1224|Proteobacteria,2VXG7@28216|Betaproteobacteria,44W2I@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6462848_5	1121035.AUCH01000012_gene2994	2.658e-43	163.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria,2KYU8@206389|Rhodocyclales	206389|Rhodocyclales	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
CMS2_k127_6462848_2	472759.Nhal_2294	3.765e-168	543.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1WWTY@135613|Chromatiales	135613|Chromatiales	FP	Belongs to the GppA Ppx family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS2_k127_6462848_1	395493.BegalDRAFT_0038	1.275e-316	982.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS2_k127_6462848_0	472759.Nhal_1290	0.0	1458.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
CMS2_k127_6462848_4	1415778.JQMM01000001_gene2119	2.157e-73	251.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1J640@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS2_k127_6514405_2	1121918.ARWE01000001_gene1748	3.705e-74	258.0	COG1404@1|root,COG2132@1|root,COG4733@1|root,COG5263@1|root,COG1404@2|Bacteria,COG2132@2|Bacteria,COG4733@2|Bacteria,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	pel3B	GO:0005575,GO:0005576	1.16.3.3,1.3.3.5,4.2.2.2,4.2.2.23	ko:K01728,ko:K06324,ko:K08100,ko:K18197,ko:K20276	ko00040,ko00860,ko01110,ko02024,map00040,map00860,map01110,map02024	-	R02361,R02394,R06240	RC00049,RC00705,RC01983	ko00000,ko00001,ko01000	-	PL11	-	Beta_helix,CBM_6,Cu-oxidase_2,DUF1080,Pec_lyase_C
CMS2_k127_6514405_0	653733.Selin_1259	0.0	1076.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS2_k127_6514405_3	1120970.AUBZ01000001_gene3694	1.892e-56	201.0	COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,1S2UP@1236|Gammaproteobacteria,467I3@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
CMS2_k127_6514405_1	378806.STAUR_0434	1.497e-105	357.0	COG1520@1|root,COG1520@2|Bacteria,1Q8PD@1224|Proteobacteria,439RP@68525|delta/epsilon subdivisions,2X54H@28221|Deltaproteobacteria,2Z03R@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6514405_4	384765.SIAM614_26121	4.129e-31	128.0	COG3278@1|root,COG3278@2|Bacteria,1N9ZN@1224|Proteobacteria,2UH1E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6514405_5	1403819.BATR01000124_gene4367	2.746e-29	121.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
CMS2_k127_6846162_1	472759.Nhal_2109	1.123e-93	310.0	COG0428@1|root,COG0428@2|Bacteria,1PMN6@1224|Proteobacteria,1SIQH@1236|Gammaproteobacteria,1X1XX@135613|Chromatiales	135613|Chromatiales	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
CMS2_k127_6846162_3	880073.Calab_3141	3.679e-18	86.0	2DSSJ@1|root,33H9V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6846162_2	671143.DAMO_1944	8.623e-82	279.0	COG0053@1|root,COG1237@1|root,COG0053@2|Bacteria,COG1237@2|Bacteria,2NPQA@2323|unclassified Bacteria	2|Bacteria	P	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K04088,ko:K06897	ko00790,map00790	M00742	R10339	RC00121	ko00000,ko00001,ko00002,ko01000	-	-	-	Cation_efflux,Lactamase_B
CMS2_k127_6846162_0	1122201.AUAZ01000010_gene2547	3.412e-165	525.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,465W7@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Di-haem cytochrome c peroxidase	ccp	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS2_k127_6851961_4	1123518.ARWI01000001_gene2445	7.568e-64	223.0	COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_6851961_3	443143.GM18_3121	8.353e-72	251.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,42U7W@68525|delta/epsilon subdivisions,2WQGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS2_k127_6851961_2	1177154.Y5S_00556	4.861e-77	269.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,1T2MP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS2_k127_6851961_0	450851.PHZ_p0154	1.796e-170	554.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,2KK9G@204458|Caulobacterales	204458|Caulobacterales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS2_k127_6851961_1	1384056.N787_01665	7.553e-122	402.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1X64I@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
CMS2_k127_6851961_5	1384056.N787_01670	2.335e-29	128.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,1X7D8@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
CMS2_k127_7037865_9	1415778.JQMM01000001_gene2119	8.891e-92	308.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1J640@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS2_k127_7037865_17	261292.Nit79A3_2142	5.162e-12	72.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,373C5@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Invasion gene expression up-regulator, SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
CMS2_k127_7037865_5	314345.SPV1_04973	2.358e-127	426.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria	1224|Proteobacteria	P	Na Pi-Cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
CMS2_k127_7037865_6	1049564.TevJSym_ad01150	5.2e-120	394.0	COG1215@1|root,COG1215@2|Bacteria,1QVAX@1224|Proteobacteria,1T3H7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.122	ko:K21366	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
CMS2_k127_7037865_13	713586.KB900536_gene1885	1.055e-44	168.0	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,1S4C9@1236|Gammaproteobacteria,1X2AK@135613|Chromatiales	135613|Chromatiales	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS2_k127_7037865_4	404589.Anae109_3474	9.211e-134	444.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,42U1I@68525|delta/epsilon subdivisions,2WQQV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_core,Transglut_i_TM
CMS2_k127_7037865_11	404589.Anae109_3475	5.868e-66	236.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,42MVH@68525|delta/epsilon subdivisions,2WMHB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
CMS2_k127_7037865_14	1499967.BAYZ01000041_gene2397	1.985e-24	120.0	COG0457@1|root,COG0457@2|Bacteria,2NRIR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_8
CMS2_k127_7037865_8	626887.J057_16225	4.477e-98	326.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1S5SK@1236|Gammaproteobacteria,468K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS2_k127_7037865_0	626887.J057_16220	0.0	1149.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,GDE_C
CMS2_k127_7037865_2	1479237.JMLY01000001_gene2644	9.994e-167	533.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,465TN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CMS2_k127_7037865_1	1479237.JMLY01000001_gene2645	3.625e-302	945.0	COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,1RTF2@1236|Gammaproteobacteria,466AF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Phosphodiest
CMS2_k127_7037865_16	1279015.KB908455_gene1271	1.767e-21	95.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,1SD8X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_7037865_10	270374.MELB17_22645	4.142e-86	287.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,46C77@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
CMS2_k127_7037865_12	545264.KB898745_gene1357	1.094e-45	171.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales	135613|Chromatiales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_7037865_15	207954.MED92_10819	2.508e-22	104.0	COG2995@1|root,COG2995@2|Bacteria,1NA1F@1224|Proteobacteria,1SERF@1236|Gammaproteobacteria,1XQ7I@135619|Oceanospirillales	135619|Oceanospirillales	S	Paraquat-inducible protein A	-	-	-	-	-	-	-	-	-	-	-	-	PqiA
CMS2_k127_7037865_7	1266908.AQPB01000055_gene1903	1.283e-105	350.0	COG1116@1|root,COG1116@2|Bacteria,1R8N0@1224|Proteobacteria,1RYBX@1236|Gammaproteobacteria,1WY77@135613|Chromatiales	135613|Chromatiales	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS2_k127_7037865_3	317025.Tcr_0033	5.818e-160	511.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RYYZ@1236|Gammaproteobacteria,461TG@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
CMS2_k127_74995_9	396588.Tgr7_2203	2.981e-139	449.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1S7EZ@1236|Gammaproteobacteria,1X01B@135613|Chromatiales	135613|Chromatiales	I	Membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS2_k127_74995_3	765913.ThidrDRAFT_3405	1.773e-226	711.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales	135613|Chromatiales	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS2_k127_74995_28	987059.RBXJA2T_19391	7.539e-10	64.0	COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2VX5E@28216|Betaproteobacteria,1KNVY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS2_k127_74995_2	713586.KB900536_gene1253	1.33e-276	861.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS2_k127_74995_16	105559.Nwat_0600	2.343e-58	212.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X2A0@135613|Chromatiales	135613|Chromatiales	M	Thrombospondin type 3 repeat	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
CMS2_k127_74995_18	395493.BegalDRAFT_3149	3.023e-49	178.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,460ZB@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CMS2_k127_74995_20	765913.ThidrDRAFT_1545	6.134e-46	173.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1WXNV@135613|Chromatiales	135613|Chromatiales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS2_k127_74995_13	1298593.TOL_3708	9.041e-63	222.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1XK5E@135619|Oceanospirillales	135619|Oceanospirillales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS2_k127_74995_11	338969.Rfer_0744	6.683e-90	308.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VQQ7@28216|Betaproteobacteria,4AJE0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS2_k127_74995_22	314345.SPV1_01617	2.686e-40	153.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria	1224|Proteobacteria	C	Domain of unknown function (DUF1924)	shp	-	-	-	-	-	-	-	-	-	-	-	DUF1924
CMS2_k127_74995_21	1049564.TevJSym_ae00870	3.853e-45	169.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,1S2S2@1236|Gammaproteobacteria,1J75E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
CMS2_k127_74995_12	207954.MED92_02319	6.274e-86	288.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1XH30@135619|Oceanospirillales	135619|Oceanospirillales	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	-	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
CMS2_k127_74995_15	768671.ThimaDRAFT_4048	6.08e-60	217.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1WZGS@135613|Chromatiales	135613|Chromatiales	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS2_k127_74995_27	530564.Psta_1413	1.351e-16	87.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	PEMT
CMS2_k127_74995_7	580332.Slit_2960	7.238e-154	492.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,44V1G@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS2_k127_74995_26	1454004.AW11_00603	1.257e-18	90.0	2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,2VW2I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3301
CMS2_k127_74995_8	713586.KB900536_gene2882	5.364e-144	461.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WX6I@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS2_k127_74995_25	396588.Tgr7_0822	1.112e-27	116.0	2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_74995_10	589865.DaAHT2_2568	6.529e-125	410.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WM2C@28221|Deltaproteobacteria,2MIPY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
CMS2_k127_74995_6	1123393.KB891328_gene703	3.681e-155	500.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VIIQ@28216|Betaproteobacteria,1KSPD@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Dehydrogenase E1 component	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
CMS2_k127_74995_5	1123392.AQWL01000004_gene2635	3.554e-176	556.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,1KSCI@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
CMS2_k127_74995_0	1123368.AUIS01000007_gene2739	0.0	1292.0	COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,2NBVW@225057|Acidithiobacillales	225057|Acidithiobacillales	C	e3 binding domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim
CMS2_k127_74995_23	525897.Dbac_2489	8.382e-39	148.0	COG1320@1|root,COG1320@2|Bacteria,1Q009@1224|Proteobacteria,42V1B@68525|delta/epsilon subdivisions,2WRJI@28221|Deltaproteobacteria,2ME6C@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit	-	-	-	ko:K05564,ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
CMS2_k127_74995_24	525897.Dbac_2488	1.573e-35	138.0	COG2212@1|root,COG2212@2|Bacteria,1N8WJ@1224|Proteobacteria	1224|Proteobacteria	P	Multisubunit Na H antiporter, MnhF subunit	phaF	-	-	ko:K05563	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MrpF_PhaF
CMS2_k127_74995_14	525897.Dbac_2487	5.151e-61	215.0	COG1863@1|root,COG1863@2|Bacteria,1RB2I@1224|Proteobacteria,42TQZ@68525|delta/epsilon subdivisions,2WQD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	antiporter	-	-	-	ko:K05562,ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
CMS2_k127_74995_4	525897.Dbac_2486	5.181e-183	585.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,42PD3@68525|delta/epsilon subdivisions,2WJ58@28221|Deltaproteobacteria,2MATX@213115|Desulfovibrionales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05561,ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
CMS2_k127_74995_19	525897.Dbac_2485	1.917e-46	171.0	COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,42V2H@68525|delta/epsilon subdivisions,2WRNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05560,ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
CMS2_k127_74995_1	525897.Dbac_2484	0.0	1281.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIWK@28221|Deltaproteobacteria,2M8CW@213115|Desulfovibrionales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05559,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
CMS2_k127_74995_17	1049564.TevJSym_an00250	2.925e-53	190.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,1JA7M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF882)	ycbK	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
CMS2_k127_75402_0	153948.NAL212_3117	0.0	1085.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase recycling family C-terminal	-	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N
CMS2_k127_75402_10	305900.GV64_20050	8.232e-58	215.0	COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,1XJC2@135619|Oceanospirillales	135619|Oceanospirillales	J	Elongation factor P	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS2_k127_75402_6	1121374.KB891576_gene372	8.556e-112	383.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS2_k127_75402_7	159087.Daro_1225	3.047e-111	372.0	2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,2VPW1@28216|Betaproteobacteria,2KV1A@206389|Rhodocyclales	206389|Rhodocyclales	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
CMS2_k127_75402_2	1049564.TevJSym_ac00480	8.929e-198	626.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS2_k127_75402_12	1056512.D515_01104	4.394e-52	187.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1XXE0@135623|Vibrionales	135623|Vibrionales	J	COG1186 Protein chain release factor B	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS2_k127_75402_13	118163.Ple7327_0409	1.06e-45	169.0	COG3871@1|root,COG3871@2|Bacteria,1GDRX@1117|Cyanobacteria	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS2_k127_75402_14	1255043.TVNIR_3361	9.272e-39	150.0	2E8UR@1|root,33355@2|Bacteria,1MYPY@1224|Proteobacteria,1S6SI@1236|Gammaproteobacteria,1WYQ0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_75402_5	713586.KB900536_gene220	5.729e-117	383.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aldo keto	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS2_k127_75402_8	1049564.TevJSym_ai00480	8.994e-103	350.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1JB93@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfatase-modifying factor enzyme 1	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS2_k127_75402_15	1027273.GZ77_11165	1.319e-28	127.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria,1XM0U@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
CMS2_k127_75402_3	713586.KB900536_gene1783	1.339e-142	476.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales	135613|Chromatiales	M	PFAM Lytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
CMS2_k127_75402_4	765912.Thimo_2695	6.662e-127	430.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales	135613|Chromatiales	M	PFAM Lytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
CMS2_k127_75402_9	1049564.TevJSym_an00800	2.383e-79	273.0	28JUY@1|root,2Z9JY@2|Bacteria,1R822@1224|Proteobacteria,1RPY0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_75402_1	1255043.TVNIR_3621	4.835e-209	655.0	28IVT@1|root,2Z8U5@2|Bacteria,1R7G9@1224|Proteobacteria,1S02A@1236|Gammaproteobacteria,1WXJ0@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_75402_16	1123393.KB891326_gene112	2.303e-25	114.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria,1KTC6@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS2_k127_75402_11	580332.Slit_1433	1.498e-57	211.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,44UZS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
CMS2_k127_75402_17	1049564.TevJSym_aq00770	2.156e-24	107.0	2CH0Z@1|root,33H8V@2|Bacteria,1NMM6@1224|Proteobacteria,1STI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_75402_19	1411123.JQNH01000001_gene2978	7.994e-09	61.0	COG5642@1|root,COG5642@2|Bacteria,1N2DF@1224|Proteobacteria,2UAMS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
CMS2_k127_797600_3	713586.KB900536_gene203	7.511e-06	51.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales	135613|Chromatiales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_797600_1	1000565.METUNv1_01367	2.797e-81	282.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2VH7G@28216|Betaproteobacteria,2KUCC@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0845 Membrane-fusion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS2_k127_797600_0	1294143.H681_01410	0.0	1056.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	yhiH	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
CMS2_k127_797600_2	520999.PROVALCAL_02935	1.573e-45	169.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,3Z8CI@586|Providencia	1236|Gammaproteobacteria	V	ABC-2 type transporter	yhhJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS2_k127_82787_5	1089439.KB902239_gene506	1.01e-07	54.0	2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_82787_7	1190603.AJYD01000067_gene3196	1.771e-06	49.0	2DS85@1|root,33EYM@2|Bacteria,1NJQN@1224|Proteobacteria,1SHH9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_82787_1	396588.Tgr7_0009	1.847e-48	181.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S27K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,MipZ
CMS2_k127_82787_4	290315.Clim_2253	2.239e-21	97.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
CMS2_k127_82787_3	479437.Elen_2326	1.634e-31	127.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS2_k127_82787_0	765912.Thimo_0169	1.507e-129	422.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1WXXR@135613|Chromatiales	135613|Chromatiales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS2_k127_82787_6	1248916.ANFY01000003_gene689	1.071e-06	58.0	COG1416@1|root,COG1416@2|Bacteria,1RI2V@1224|Proteobacteria,2U98Z@28211|Alphaproteobacteria,2K5CI@204457|Sphingomonadales	204457|Sphingomonadales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS2_k127_82787_2	396588.Tgr7_2897	2.691e-37	152.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS2_k127_870572_37	243159.AFE_0008	1.655e-20	96.0	COG5430@1|root,COG5430@2|Bacteria,1MZNQ@1224|Proteobacteria,1T0UD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Spore Coat	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
CMS2_k127_870572_30	1255043.TVNIR_3688	1.751e-45	168.0	COG3874@1|root,COG3874@2|Bacteria,1N4RT@1224|Proteobacteria,1SQI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
CMS2_k127_870572_31	1255043.TVNIR_3689	6.207e-44	166.0	2E21G@1|root,32X98@2|Bacteria,1N21H@1224|Proteobacteria,1SSTY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
CMS2_k127_870572_21	1121374.KB891580_gene1800	6.118e-79	271.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the SfsA family	sfsA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
CMS2_k127_870572_8	472759.Nhal_0533	2.275e-178	567.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales	135613|Chromatiales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS2_k127_870572_17	998674.ATTE01000001_gene2405	1.887e-92	310.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,460DG@72273|Thiotrichales	72273|Thiotrichales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS2_k127_870572_27	675815.VOA_002218	3.158e-62	219.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XSNS@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	TLL0138	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
CMS2_k127_870572_5	323261.Noc_2672	1.212e-200	649.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales	135613|Chromatiales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS2_k127_870572_19	323261.Noc_2673	9.468e-87	291.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS2_k127_870572_32	1049564.TevJSym_al00470	1.368e-40	154.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1J6HT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0848 Biopolymer transport protein	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS2_k127_870572_6	713586.KB900536_gene312	1.97e-196	628.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales	135613|Chromatiales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS2_k127_870572_15	323261.Noc_2676	3.332e-109	363.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales	135613|Chromatiales	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS2_k127_870572_35	697282.Mettu_1037	6.819e-24	101.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1XFSG@135618|Methylococcales	135618|Methylococcales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
CMS2_k127_870572_18	227377.CBU_0479	5.851e-87	293.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1JD1B@118969|Legionellales	118969|Legionellales	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS2_k127_870572_28	768671.ThimaDRAFT_2888	2.899e-60	212.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales	135613|Chromatiales	T	low molecular weight	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS2_k127_870572_29	396588.Tgr7_1818	7.239e-51	190.0	COG3221@1|root,COG3221@2|Bacteria,1NBWA@1224|Proteobacteria,1TKA1@1236|Gammaproteobacteria,1X0ZP@135613|Chromatiales	135613|Chromatiales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS2_k127_870572_3	1122139.KB907872_gene2252	6.203e-234	761.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XHTN@135619|Oceanospirillales	135619|Oceanospirillales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS2_k127_870572_12	1122599.AUGR01000004_gene2098	8.646e-114	376.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XH2T@135619|Oceanospirillales	135619|Oceanospirillales	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS2_k127_870572_22	765911.Thivi_2189	2.827e-77	265.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1WVZ9@135613|Chromatiales	135613|Chromatiales	S	subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS2_k127_870572_13	1049564.TevJSym_al00350	1.321e-111	369.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1JA17@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS2_k127_870572_42	1215092.PA6_008_01710	0.0003709	52.0	COG3675@1|root,COG3675@2|Bacteria,1NICA@1224|Proteobacteria,1SHG9@1236|Gammaproteobacteria,1YDR8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Lipase (class 3)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
CMS2_k127_870572_25	207954.MED92_09666	5.868e-75	256.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XJND@135619|Oceanospirillales	135619|Oceanospirillales	D	Maf-like protein	maf-2	-	-	-	-	-	-	-	-	-	-	-	Maf
CMS2_k127_870572_0	572477.Alvin_1668	2.206e-291	905.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales	135613|Chromatiales	CI	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
CMS2_k127_870572_2	765914.ThisiDRAFT_2156	2.545e-234	734.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales	135613|Chromatiales	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS2_k127_870572_34	1049564.TevJSym_bc00100	6.853e-34	137.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1J6U0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS2_k127_870572_36	2340.JV46_14820	1.039e-22	98.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1J6TX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS2_k127_870572_10	396588.Tgr7_1912	2.724e-147	474.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS2_k127_870572_9	2340.JV46_14790	1.016e-160	511.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1J5D9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360	ACP_syn_III,ACP_syn_III_C
CMS2_k127_870572_11	66269.NL54_01000	4.82e-122	398.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,3VYST@53335|Pantoea	1236|Gammaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
CMS2_k127_870572_16	717772.THIAE_03170	6.731e-104	343.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,45ZWN@72273|Thiotrichales	72273|Thiotrichales	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS2_k127_870572_33	519989.ECTPHS_03217	1.701e-35	136.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1WYUG@135613|Chromatiales	135613|Chromatiales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS2_k127_870572_4	754476.Q7A_2012	1.176e-202	637.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS2_k127_870572_20	323261.Noc_1662	2.358e-83	284.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
CMS2_k127_870572_14	1049564.TevJSym_bc00190	2.364e-111	370.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1J56S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS2_k127_870572_43	153948.NAL212_0521	0.0004867	48.0	29Z5M@1|root,30M3C@2|Bacteria,1PI6J@1224|Proteobacteria,2W6T4@28216|Betaproteobacteria,374H2@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_870572_24	391615.ABSJ01000024_gene245	2.912e-76	261.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1JA0E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	yccA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
CMS2_k127_870572_40	1168059.KB899087_gene1061	2.405e-07	54.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS2_k127_870572_39	637389.Acaty_c0776	1.706e-07	62.0	COG3266@1|root,COG3266@2|Bacteria,1NQBT@1224|Proteobacteria	1224|Proteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS2_k127_870572_7	1049564.TevJSym_aa01890	1.056e-182	585.0	COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,1RYGW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CMS2_k127_870572_23	1219080.VEZ01S_14_00070	1.011e-76	262.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1XUFX@135623|Vibrionales	135623|Vibrionales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	sirA	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS2_k127_870572_1	754477.Q7C_1086	2.055e-255	802.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,45ZPV@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS2_k127_870572_26	395493.BegalDRAFT_1254	1.67e-68	237.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,460R8@72273|Thiotrichales	72273|Thiotrichales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS2_k127_870572_41	66875.JODY01000017_gene500	7.822e-06	48.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS2_k127_92062_3	1283300.ATXB01000001_gene1694	1.18e-196	615.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria,1XFZ1@135618|Methylococcales	135618|Methylococcales	C	ATP synthase alpha/beta chain, C terminal domain	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS2_k127_92062_17	1283300.ATXB01000001_gene1695	1.314e-54	195.0	COG0355@1|root,COG0355@2|Bacteria,1RKXG@1224|Proteobacteria,1SAMJ@1236|Gammaproteobacteria,1XGQD@135618|Methylococcales	135618|Methylococcales	C	ATP synthase, Delta/Epsilon chain, beta-sandwich domain	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CMS2_k127_92062_20	857087.Metme_0500	5.659e-35	139.0	2CBNW@1|root,32RTR@2|Bacteria,1N7RB@1224|Proteobacteria,1SAT0@1236|Gammaproteobacteria,1XGK0@135618|Methylococcales	135618|Methylococcales	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
CMS2_k127_92062_26	344747.PM8797T_02729	6.211e-06	52.0	2E6XU@1|root,331H5@2|Bacteria,2J18Y@203682|Planctomycetes	203682|Planctomycetes	S	N-ATPase, AtpR subunit	-	-	-	-	-	-	-	-	-	-	-	-	AtpR
CMS2_k127_92062_8	1283300.ATXB01000001_gene1697	1.796e-115	375.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1S0SN@1236|Gammaproteobacteria,1XFZV@135618|Methylococcales	135618|Methylococcales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS2_k127_92062_19	1288826.MSNKSG1_04281	1.73e-40	153.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria,46B92@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS2_k127_92062_12	1283300.ATXB01000001_gene1698	1.909e-68	240.0	COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,1S5EV@1236|Gammaproteobacteria,1XGGZ@135618|Methylococcales	135618|Methylococcales	C	ATP synthase B/B' CF(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS2_k127_92062_1	1283300.ATXB01000001_gene1699	6.653e-262	813.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria,1XG8P@135618|Methylococcales	135618|Methylococcales	C	ATP synthase alpha/beta chain, C terminal domain	-	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS2_k127_92062_7	1283300.ATXB01000001_gene1701	5.104e-138	444.0	COG0224@1|root,COG0224@2|Bacteria,1N4GR@1224|Proteobacteria,1RYRI@1236|Gammaproteobacteria,1XGC7@135618|Methylococcales	135618|Methylococcales	C	ATP synthase	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS2_k127_92062_5	1283300.ATXB01000001_gene1555	3.126e-152	490.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,1S28T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
CMS2_k127_92062_15	1123514.KB905899_gene479	3.379e-58	207.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1S99C@1236|Gammaproteobacteria,463J4@72273|Thiotrichales	72273|Thiotrichales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS2_k127_92062_22	1056820.KB900699_gene1195	9.637e-31	130.0	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,2PQ83@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_92062_13	1121935.AQXX01000142_gene2326	1.406e-62	233.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1XNEQ@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_92062_2	1283300.ATXB01000001_gene1705	7.604e-242	759.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1SZW9@1236|Gammaproteobacteria,1XFPE@135618|Methylococcales	135618|Methylococcales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
CMS2_k127_92062_24	1283300.ATXB01000001_gene1553	6.425e-26	109.0	COG1403@1|root,COG1403@2|Bacteria,1QTCI@1224|Proteobacteria,1SV2C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_92062_18	713586.KB900536_gene2278	2.01e-46	171.0	2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,1S4GF@1236|Gammaproteobacteria,1WY9W@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF3775)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3775
CMS2_k127_92062_9	439235.Dalk_0314	4.428e-103	341.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42NZI@68525|delta/epsilon subdivisions,2WIT8@28221|Deltaproteobacteria,2MIH4@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
CMS2_k127_92062_23	472759.Nhal_2150	2.173e-29	126.0	COG0328@1|root,COG0328@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H,RVT_1,RVT_3
CMS2_k127_92062_6	118163.Ple7327_0643	5.079e-145	468.0	COG2843@1|root,COG2843@2|Bacteria,1G20Q@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS2_k127_92062_11	118163.Ple7327_0355	1.01e-84	287.0	COG1801@1|root,COG1801@2|Bacteria,1G2CT@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG1801 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS2_k127_92062_16	269799.Gmet_2409	9.659e-58	209.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42SWA@68525|delta/epsilon subdivisions,2WPE1@28221|Deltaproteobacteria,43W0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS2_k127_92062_10	338963.Pcar_2787	2.284e-97	327.0	COG1748@1|root,COG1748@2|Bacteria,1QY0D@1224|Proteobacteria	1224|Proteobacteria	E	Saccharopine dehydrogenase	-	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C
CMS2_k127_92062_14	472759.Nhal_0793	4.15e-60	212.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
CMS2_k127_92062_25	1255043.TVNIR_1089	7.366e-20	93.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,1SJ4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS2_k127_92062_21	472759.Nhal_0793	2.21e-31	129.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
CMS2_k127_92062_4	1283300.ATXB01000001_gene1710	1.354e-167	548.0	COG0637@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,1RNIQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495	Trehalose_PPase
CMS2_k127_92062_0	1232410.KI421426_gene1372	0.0	1033.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,42Q4Z@68525|delta/epsilon subdivisions,2WM28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase
CMS2_k127_95304_7	1535422.ND16A_3099	1.285e-29	122.0	2BKN5@1|root,32F3J@2|Bacteria,1RIMC@1224|Proteobacteria,1S6Q3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS2_k127_95304_5	207954.MED92_06726	4.211e-59	205.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XJH4@135619|Oceanospirillales	135619|Oceanospirillales	K	at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA)	glnK-2	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
CMS2_k127_95304_1	28258.KP05_01520	1.643e-209	657.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XI6M@135619|Oceanospirillales	135619|Oceanospirillales	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS2_k127_95304_6	1407650.BAUB01000003_gene754	7.238e-34	131.0	COG3369@1|root,COG3369@2|Bacteria,1G7ZE@1117|Cyanobacteria,1H4B8@1129|Synechococcus	1117|Cyanobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CMS2_k127_95304_4	765914.ThisiDRAFT_2535	5.273e-74	254.0	COG1136@1|root,COG1136@2|Bacteria,1RH0D@1224|Proteobacteria,1T21A@1236|Gammaproteobacteria,1X2P3@135613|Chromatiales	135613|Chromatiales	V	pfam abc	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS2_k127_95304_3	765914.ThisiDRAFT_2469	1.397e-122	398.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1WW8S@135613|Chromatiales	135613|Chromatiales	S	PFAM conserved	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
CMS2_k127_95304_2	1116472.MGMO_112c00140	1.214e-127	413.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1XDNB@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
CMS2_k127_95304_0	1123368.AUIS01000007_gene2817	9.743e-246	772.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,2NBQ1@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CMS2_k127_990130_7	1049564.TevJSym_aa00630	4.027e-34	133.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,1T1HX@1236|Gammaproteobacteria,1JC34@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS2_k127_990130_2	1123487.KB892834_gene2803	2.794e-63	224.0	COG1246@1|root,COG1595@1|root,COG1246@2|Bacteria,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,2VRKX@28216|Betaproteobacteria,2KWKE@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS2_k127_990130_1	768671.ThimaDRAFT_2377	1.389e-172	544.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1WX27@135613|Chromatiales	135613|Chromatiales	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS2_k127_990130_10	1123401.JHYQ01000002_gene2573	1.013e-10	64.0	2EENH@1|root,338GC@2|Bacteria,1N9EC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_990130_8	580332.Slit_1002	6.026e-32	131.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
CMS2_k127_990130_6	102129.Lepto7375DRAFT_6747	2.799e-34	136.0	COG2050@1|root,COG2050@2|Bacteria,1G7HG@1117|Cyanobacteria	1117|Cyanobacteria	Q	Putative thioesterase (yiiD_Cterm)	-	-	-	-	-	-	-	-	-	-	-	-	YiiD_C
CMS2_k127_990130_5	1123368.AUIS01000010_gene2354	2.629e-47	174.0	2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,1S4WN@1236|Gammaproteobacteria,2ND0V@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS2_k127_990130_9	876044.IMCC3088_2206	1.448e-24	103.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
CMS2_k127_990130_0	1217718.ALOU01000049_gene4368	0.0	1265.0	COG0243@1|root,COG0243@2|Bacteria,1MX0A@1224|Proteobacteria,2VI0G@28216|Betaproteobacteria,1KBQ7@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	aoxB	-	1.20.2.1,1.20.9.1	ko:K08356	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.6	-	-	Molybdopterin,Molydop_binding
CMS2_k127_990130_3	75379.Tint_3062	2.877e-59	209.0	COG0723@1|root,COG0723@2|Bacteria,1RF8Q@1224|Proteobacteria,2VR6G@28216|Betaproteobacteria,1KMTP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Rieske [2Fe-2S] domain	aoxA	-	1.20.2.1,1.20.9.1	ko:K08355	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.6	-	-	Rieske,TAT_signal
CMS2_k127_990130_4	1123368.AUIS01000033_gene1371	1.537e-52	190.0	COG0454@1|root,COG0456@2|Bacteria,1N506@1224|Proteobacteria,1S97J@1236|Gammaproteobacteria,2NDC1@225057|Acidithiobacillales	225057|Acidithiobacillales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
## 2868 queries scanned
## Total time (seconds): 49.215551137924194
## Rate: 58.27 q/s