## Sat Nov  9 15:56:51 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS3_bin.120.fa -m mmseqs --itype genome -o CMS3_bin.120 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS3_bin.120 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS3_k127_1011592_16	886293.Sinac_5019	1.897e-18	92.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_1011592_11	649349.Lbys_2682	6.67e-45	181.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1011592_0	469383.Cwoe_2565	2.035e-239	761.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CR1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1011592_5	234267.Acid_2601	2.233e-120	405.0	COG1167@1|root,COG1167@2|Bacteria,3Y3WK@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
CMS3_k127_1011592_18	1122604.JONR01000033_gene54	2.034e-05	59.0	COG1807@1|root,COG1807@2|Bacteria,1N5QJ@1224|Proteobacteria,1SM4K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1011592_12	234267.Acid_6183	1.935e-42	181.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_1011592_7	1385515.N791_02895	2.132e-82	296.0	COG0474@1|root,COG0474@2|Bacteria,1QWMC@1224|Proteobacteria,1T25Y@1236|Gammaproteobacteria,1XD5G@135614|Xanthomonadales	135614|Xanthomonadales	P	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
CMS3_k127_1011592_17	697281.Mahau_1499	4.453e-09	69.0	COG0746@1|root,COG0746@2|Bacteria,1V4AK@1239|Firmicutes,249SR@186801|Clostridia,42EKJ@68295|Thermoanaerobacterales	186801|Clostridia	H	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS3_k127_1011592_14	1267534.KB906759_gene2008	1.332e-38	165.0	COG0354@1|root,COG0354@2|Bacteria,3Y2PI@57723|Acidobacteria,2JJ3H@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
CMS3_k127_1011592_15	867845.KI911784_gene1635	5.771e-22	111.0	COG3222@1|root,COG3222@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS3_k127_1011592_10	1101190.ARWB01000001_gene1479	3.381e-49	185.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,36YHJ@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Nitrogen regulatory protein P-II	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_1011592_1	290397.Adeh_4252	2.183e-213	673.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2YUPP@29|Myxococcales	28221|Deltaproteobacteria	H	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_1011592_13	402881.Plav_0028	1.911e-39	160.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TUB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_1011592_9	670307.HYPDE_39993	3.988e-59	226.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,3N62S@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS3_k127_1011592_6	1125863.JAFN01000001_gene2756	5.935e-102	340.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS3_k127_1011592_8	1123487.KB892834_gene2764	1.847e-75	276.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,2KV20@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_1011592_3	338963.Pcar_2420	1.103e-142	471.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,43U09@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS3_k127_1011592_4	96561.Dole_2490	4.151e-131	464.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2MHTS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
CMS3_k127_1011592_2	335543.Sfum_0290	1.186e-167	558.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MSIQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transglycosylase	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
CMS3_k127_1014593_3	566466.NOR53_3652	1.829e-64	232.0	COG0845@1|root,COG0845@2|Bacteria,1QWRP@1224|Proteobacteria	1224|Proteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
CMS3_k127_1014593_1	251221.35211992	5.459e-113	389.0	COG0577@1|root,COG0577@2|Bacteria,1G20M@1117|Cyanobacteria	1117|Cyanobacteria	V	TIGRFAM DevC protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_1014593_2	395961.Cyan7425_2892	1.944e-103	369.0	COG1136@1|root,COG2203@1|root,COG1136@2|Bacteria,COG2203@2|Bacteria,1G1SM@1117|Cyanobacteria,3KJGB@43988|Cyanothece	1117|Cyanobacteria	V	TIGRFAM ABC exporter ATP-binding subunit, DevA family	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1014593_5	671143.DAMO_1274	1.676e-08	67.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	QU41_28450	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_1014593_4	96561.Dole_0563	4.007e-43	174.0	2A4CF@1|root,30SY3@2|Bacteria,1RFXP@1224|Proteobacteria,42RIM@68525|delta/epsilon subdivisions,2WNS6@28221|Deltaproteobacteria,2MNMZ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS3_k127_1014593_0	243090.RB9119	2.435e-138	454.0	COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes	203682|Planctomycetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_1029725_6	946483.Cenrod_0412	3.138e-05	53.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,4A9K3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CMS3_k127_1029725_5	330214.NIDE0518	8.807e-30	129.0	COG2802@1|root,COG2802@2|Bacteria,3J13Q@40117|Nitrospirae	40117|Nitrospirae	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
CMS3_k127_1029725_3	1192034.CAP_3131	4.517e-65	241.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2YTT2@29|Myxococcales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS3_k127_1029725_2	1121949.AQXT01000002_gene1708	1.181e-73	258.0	COG1216@1|root,COG1216@2|Bacteria,1QY6A@1224|Proteobacteria,2TXHY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1029725_1	439292.Bsel_1864	1.113e-103	365.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes	1239|Firmicutes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_1029725_0	525904.Tter_2623	4.163e-104	355.0	COG1060@1|root,COG1060@2|Bacteria,2NP8W@2323|unclassified Bacteria	2|Bacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	fbiC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,Radical_SAM
CMS3_k127_1029725_4	1384056.N787_06140	5.17e-48	194.0	COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria,1RMRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_4,PAS_9,dCache_1
CMS3_k127_1040510_10	1122247.C731_4436	2.036e-09	61.0	COG1028@1|root,COG1028@2|Bacteria,2ID9A@201174|Actinobacteria,23803@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_1040510_0	525368.HMPREF0591_2258	7.896e-233	747.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,23787@1762|Mycobacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_1040510_2	357808.RoseRS_2835	1.492e-182	591.0	COG4030@1|root,COG4030@2|Bacteria,2G67Q@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS3_k127_1040510_6	1121949.AQXT01000002_gene1410	8.994e-69	267.0	COG1804@1|root,COG1804@2|Bacteria,1MX0I@1224|Proteobacteria,2U2RY@28211|Alphaproteobacteria,43ZKU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_1040510_1	717774.Marme_2197	2.997e-184	588.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHAV@135619|Oceanospirillales	135619|Oceanospirillales	Q	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS3_k127_1040510_7	502025.Hoch_2601	1.533e-58	212.0	COG4665@1|root,COG4665@2|Bacteria,1R4Q7@1224|Proteobacteria,42V05@68525|delta/epsilon subdivisions,2WQVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS3_k127_1040510_3	502025.Hoch_2600	3.343e-144	467.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2WKJP@28221|Deltaproteobacteria,2Z1DV@29|Myxococcales	28221|Deltaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_1040510_4	113395.AXAI01000002_gene5234	1.382e-87	297.0	COG2141@1|root,COG2141@2|Bacteria,1QZQ7@1224|Proteobacteria,2UQHY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_1040510_5	247634.GPB2148_744	2.803e-85	292.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,1RRUK@1236|Gammaproteobacteria,1J5NX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_1040510_8	439235.Dalk_1881	1.789e-32	142.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1043891_28	1440053.JOEI01000007_gene2532	9.988e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_1043891_18	1499967.BAYZ01000073_gene2049	3.355e-40	166.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
CMS3_k127_1043891_11	1280952.HJA_06292	5.479e-63	246.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TXAG@28211|Alphaproteobacteria,440ZA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS3_k127_1043891_34	1109445.AGSX01000053_gene2108	0.0008829	51.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1T178@1236|Gammaproteobacteria,1Z4EY@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS3_k127_1043891_9	414684.RC1_0799	3.822e-68	242.0	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,2UA8C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
CMS3_k127_1043891_4	414684.RC1_0800	5.854e-110	392.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,2TU50@28211|Alphaproteobacteria,2JSBB@204441|Rhodospirillales	204441|Rhodospirillales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_1043891_15	1122137.AQXF01000001_gene2819	5.008e-50	183.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,2UAB1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	TonB system transport protein ExbB	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_1043891_23	1515746.HR45_05900	5.809e-32	133.0	COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RQPV@1236|Gammaproteobacteria,2Q8TC@267890|Shewanellaceae	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_1043891_10	1265313.HRUBRA_01305	1.305e-64	244.0	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1J575@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_8
CMS3_k127_1043891_14	1415780.JPOG01000001_gene223	2.547e-51	184.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria,1X7VH@135614|Xanthomonadales	135614|Xanthomonadales	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_1043891_22	1384056.N787_03245	7.251e-33	139.0	COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,1X60S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS3_k127_1043891_33	1123257.AUFV01000011_gene3054	6.537e-05	55.0	2E7KC@1|root,3322E@2|Bacteria,1PUQ1@1224|Proteobacteria,1TAQ9@1236|Gammaproteobacteria,1XBP4@135614|Xanthomonadales	135614|Xanthomonadales	S	multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1043891_20	1121439.dsat_0446	1.073e-38	156.0	COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,2MBT8@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_1043891_32	1121013.P873_14015	2.966e-05	57.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1X5UT@135614|Xanthomonadales	135614|Xanthomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_1043891_2	1137799.GZ78_07780	1.484e-149	508.0	COG1960@1|root,COG1960@2|Bacteria,1R6EH@1224|Proteobacteria,1RMXW@1236|Gammaproteobacteria,1XRH0@135619|Oceanospirillales	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1043891_16	688245.CtCNB1_1331	6.707e-47	190.0	COG1545@1|root,COG1545@2|Bacteria,1R44D@1224|Proteobacteria,2VPTX@28216|Betaproteobacteria,4AFPP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,MaoC_dehydrat_N,OB_aCoA_assoc
CMS3_k127_1043891_5	745310.G432_15905	1.557e-109	366.0	COG1960@1|root,COG1960@2|Bacteria,1PRJJ@1224|Proteobacteria,2UQWF@28211|Alphaproteobacteria,2K1XZ@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_1043891_0	305900.GV64_19595	1.12e-162	548.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,1RN81@1236|Gammaproteobacteria,1XP6T@135619|Oceanospirillales	135619|Oceanospirillales	I	COG0183 Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1043891_6	331869.BAL199_25719	1.321e-107	363.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,4BPRH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_1043891_26	1041522.MCOL_V203325	6.867e-24	106.0	2AUCB@1|root,31K05@2|Bacteria,2IK3D@201174|Actinobacteria,239I4@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_1043891_21	1123250.KB908384_gene1354	2.274e-36	157.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4H336@909932|Negativicutes	909932|Negativicutes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS3_k127_1043891_19	1116472.MGMO_152c00140	1.957e-39	160.0	2CKY4@1|root,33K9I@2|Bacteria,1R395@1224|Proteobacteria,1T652@1236|Gammaproteobacteria,1XF7F@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1043891_17	671143.DAMO_2903	3.581e-41	163.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CMS3_k127_1043891_3	472759.Nhal_0414	5.952e-119	400.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1043891_31	382464.ABSI01000010_gene3256	4.679e-06	59.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,MORN,MORN_2
CMS3_k127_1043891_7	316067.Geob_2508	5.445e-82	283.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS3_k127_1043891_13	1394178.AWOO02000028_gene5382	2.941e-52	211.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria,4EFU2@85012|Streptosporangiales	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_1043891_29	479433.Caci_7456	2.4e-13	81.0	COG2186@1|root,COG2186@2|Bacteria,2I90D@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS3_k127_1043891_24	1278073.MYSTI_01584	1.279e-30	138.0	COG0604@1|root,COG0604@2|Bacteria,1NMWZ@1224|Proteobacteria,43EYN@68525|delta/epsilon subdivisions,2X2MB@28221|Deltaproteobacteria,2YTSC@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
CMS3_k127_1043891_1	1282876.BAOK01000001_gene1191	4.759e-151	494.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,2TSN9@28211|Alphaproteobacteria,4BRA0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_1043891_30	765420.OSCT_0664	2.312e-08	68.0	COG1287@1|root,COG1287@2|Bacteria,2GANB@200795|Chloroflexi,376UI@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1043891_25	1283299.AUKG01000003_gene378	3.905e-30	131.0	COG1309@1|root,COG1309@2|Bacteria,2GMVQ@201174|Actinobacteria,4CS1Z@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1043891_8	7719.XP_002125844.1	1.426e-68	253.0	COG5285@1|root,KOG3290@2759|Eukaryota,38EX9@33154|Opisthokonta,3B9VM@33208|Metazoa,3CV1M@33213|Bilateria,488Y9@7711|Chordata	33208|Metazoa	I	phytanoyl-CoA dioxygenase activity	PHYH	GO:0001561,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006103,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006720,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0008198,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019395,GO:0019752,GO:0030258,GO:0031406,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043648,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0048037,GO:0048244,GO:0051179,GO:0051186,GO:0051213,GO:0051234,GO:0051641,GO:0051649,GO:0055114,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097089,GO:1901575	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_1043891_27	1380390.JIAT01000010_gene3953	3.903e-15	89.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1043891_12	1123242.JH636435_gene833	6.273e-54	209.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_1057230_37	324602.Caur_0645	1.109e-33	140.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,375MK@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS3_k127_1057230_16	479434.Sthe_2324	3.066e-90	308.0	COG0407@1|root,COG0407@2|Bacteria,2G5NU@200795|Chloroflexi,27XWH@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS3_k127_1057230_11	59538.XP_005974719.1	5.437e-104	358.0	COG1960@1|root,KOG0141@2759|Eukaryota,38CQN@33154|Opisthokonta,3BAWC@33208|Metazoa,3CTM0@33213|Bilateria,4808A@7711|Chordata,48YSQ@7742|Vertebrata,3JC6P@40674|Mammalia,4J50Y@91561|Cetartiodactyla	2759|Eukaryota	EI	isovaleryl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1057230_6	1121106.JQKB01000055_gene5580	5.253e-151	505.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TQRA@28211|Alphaproteobacteria,2JPQZ@204441|Rhodospirillales	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1057230_10	1000565.METUNv1_00180	3.259e-107	380.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,2KU8H@206389|Rhodocyclales	206389|Rhodocyclales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CMS3_k127_1057230_21	484770.UFO1_2690	4.78e-82	290.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H2XJ@909932|Negativicutes	909932|Negativicutes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_1057230_25	935845.JADQ01000077_gene735	2.734e-70	249.0	COG2334@1|root,COG2334@2|Bacteria,1UPI8@1239|Firmicutes,4HD41@91061|Bacilli,26VR4@186822|Paenibacillaceae	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_1057230_1	335543.Sfum_0043	1.254e-268	859.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2MQYS@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_1057230_39	1121949.AQXT01000002_gene237	1.18e-24	119.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,43XVS@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS3_k127_1057230_13	1192034.CAP_3447	1.368e-99	349.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,42RUS@68525|delta/epsilon subdivisions,2WNWT@28221|Deltaproteobacteria,2YWXA@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CMS3_k127_1057230_28	56110.Oscil6304_4939	9.178e-59	224.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73	ko:K00852,ko:K00856,ko:K10710,ko:K22026	ko00030,ko00230,ko00240,ko01100,map00030,map00230,map00240,map01100	-	R00185,R00513,R01051,R01131,R01228,R02750,R08124	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_1057230_18	926564.KI911630_gene3150	1.432e-85	300.0	2DBT1@1|root,2ZAV2@2|Bacteria,2H4J7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1057230_4	247633.GP2143_12821	2.795e-177	565.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RZUZ@1236|Gammaproteobacteria,1J9Y6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	estC	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1057230_9	1205680.CAKO01000009_gene4060	3.643e-127	415.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,2JQJB@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS3_k127_1057230_34	324602.Caur_1345	1.462e-40	169.0	COG3119@1|root,COG3119@2|Bacteria,2G7YZ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_1057230_2	1207063.P24_04859	1.853e-205	652.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,2JPPA@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_1057230_5	1333998.M2A_1357	2.849e-156	502.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,4BPJW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS3_k127_1057230_12	1429916.X566_04500	6.734e-101	353.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2TR29@28211|Alphaproteobacteria,3K2MT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_1057230_40	1125863.JAFN01000001_gene2831	5.771e-24	118.0	2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,42W32@68525|delta/epsilon subdivisions,2WQGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1057230_35	469383.Cwoe_4876	2.513e-39	157.0	COG1309@1|root,COG1309@2|Bacteria,2IB4X@201174|Actinobacteria,4CSQ6@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1057230_26	1489678.RDMS_12985	8.124e-69	250.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	zitB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	iNRG857_1313.NRG857_03325,iPC815.YPO1129	Cation_efflux,ZT_dimer
CMS3_k127_1057230_42	394221.Mmar10_2108	6.409e-15	83.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1057230_7	1333998.M2A_0365	1.035e-136	455.0	COG1633@1|root,COG1633@2|Bacteria,1R02H@1224|Proteobacteria,2TYHQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_1057230_38	298653.Franean1_2285	2.887e-26	126.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS3_k127_1057230_24	502025.Hoch_2073	6.442e-73	271.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,42TE9@68525|delta/epsilon subdivisions,2WPGF@28221|Deltaproteobacteria,2YUH5@29|Myxococcales	28221|Deltaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1057230_15	1313172.YM304_16870	1.043e-90	307.0	COG2267@1|root,COG2267@2|Bacteria,2GJNF@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
CMS3_k127_1057230_27	1128398.Curi_c07140	1.534e-67	254.0	COG3118@1|root,COG3118@2|Bacteria,1UI3G@1239|Firmicutes,25FW5@186801|Clostridia	186801|Clostridia	O	belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,Thioredoxin
CMS3_k127_1057230_31	330214.NIDE2066	7.972e-53	192.0	2B047@1|root,31SEM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1057230_32	330214.NIDE2065	2.935e-47	184.0	2B047@1|root,31SEM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1057230_29	330214.NIDE2064	2.03e-56	204.0	2ATAH@1|root,31ITJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1057230_36	330214.NIDE2063	4.967e-37	145.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	osmE	GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896	-	ko:K04064,ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	OmpA,SmpA_OmlA
CMS3_k127_1057230_30	96561.Dole_1514	1.515e-55	213.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2WK3K@28221|Deltaproteobacteria,2MM49@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
CMS3_k127_1057230_17	1282876.BAOK01000002_gene552	9.708e-89	306.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_16345	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_1057230_14	467661.RKLH11_16	2.097e-94	329.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2TU33@28211|Alphaproteobacteria,3ZGVC@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	H	ABC-type tungstate transport system, permease component	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
CMS3_k127_1057230_20	187272.Mlg_2739	2.447e-83	285.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,1S5GB@1236|Gammaproteobacteria,1X0RK@135613|Chromatiales	135613|Chromatiales	P	ABC transporter	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
CMS3_k127_1057230_22	1123229.AUBC01000001_gene1639	1.132e-81	278.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria,3JUNT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	ABC-type tungstate transport system, periplasmic component	MA20_34300	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
CMS3_k127_1057230_8	187272.Mlg_0270	9.823e-129	426.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_1057230_0	1049564.TevJSym_af00420	0.0	1378.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1J56P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS3_k127_1057230_19	448385.sce3153	6.242e-84	289.0	COG0670@1|root,COG0670@2|Bacteria,1R7VN@1224|Proteobacteria,43DVQ@68525|delta/epsilon subdivisions,2WZ04@28221|Deltaproteobacteria,2Z11K@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
CMS3_k127_1057230_43	1297570.MESS4_820041	8.39e-10	68.0	COG0457@1|root,COG0457@2|Bacteria,1R718@1224|Proteobacteria,2U3AD@28211|Alphaproteobacteria,43P7F@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
CMS3_k127_1057230_3	1283300.ATXB01000001_gene817	2.095e-183	583.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1XEM7@135618|Methylococcales	135618|Methylococcales	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS3_k127_1057230_41	1343739.PAP_04595	7.618e-19	96.0	COG1011@1|root,arCOG02291@2157|Archaea,2XUJR@28890|Euryarchaeota,2431M@183968|Thermococci	183968|Thermococci	S	haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_1057230_23	1168065.DOK_03638	2.52e-76	266.0	COG1028@1|root,COG1028@2|Bacteria,1R6W8@1224|Proteobacteria,1RY7D@1236|Gammaproteobacteria,1J8ZG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_1057230_33	1121937.AUHJ01000001_gene813	1.095e-46	184.0	COG0451@1|root,COG0451@2|Bacteria,1RGHF@1224|Proteobacteria,1RQTC@1236|Gammaproteobacteria,4696K@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_1071505_7	717605.Theco_1107	1.52e-114	398.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
CMS3_k127_1071505_18	765420.OSCT_0889	9.983e-22	109.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS3_k127_1071505_19	1121324.CLIT_24c00190	4.186e-21	110.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	-	-	3.1.3.87	ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07394	RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Put_Phosphatase
CMS3_k127_1071505_9	1121945.ATXS01000007_gene506	9.595e-88	326.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
CMS3_k127_1071505_14	530564.Psta_1177	1.705e-46	179.0	COG2040@1|root,COG2040@2|Bacteria,2J3GR@203682|Planctomycetes	203682|Planctomycetes	H	Homocysteine S-methyltransferase	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
CMS3_k127_1071505_6	1128421.JAGA01000001_gene2177	2.888e-119	407.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
CMS3_k127_1071505_1	1229780.BN381_130373	1.199e-153	497.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_1071505_24	1122247.C731_4351	2.034e-09	72.0	COG5517@1|root,COG5517@2|Bacteria,2GR5G@201174|Actinobacteria,23BED@1762|Mycobacteriaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_1071505_25	1298864.AUEQ01000011_gene193	2.171e-07	66.0	COG5517@1|root,COG5517@2|Bacteria,2IHV4@201174|Actinobacteria,239DS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_1071505_10	1313172.YM304_03250	1.076e-80	294.0	COG1804@1|root,COG1804@2|Bacteria,2IB98@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_1071505_0	331869.BAL199_15903	2.089e-235	747.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,4BRUQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Flavin-binding monooxygenase-like	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3
CMS3_k127_1071505_22	1131269.AQVV01000032_gene312	1.834e-12	79.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_1071505_21	338966.Ppro_1650	1.454e-15	79.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,42WU5@68525|delta/epsilon subdivisions,2WRRS@28221|Deltaproteobacteria,43SRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS3_k127_1071505_3	1333998.M2A_2718	5.631e-140	479.0	COG0477@1|root,COG0477@2|Bacteria,1R02N@1224|Proteobacteria,2TYHV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_1071505_12	555088.DealDRAFT_1045	2.073e-65	243.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42JWH@68298|Syntrophomonadaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_1071505_16	1210908.HSB1_09330	1.223e-34	145.0	COG3332@1|root,arCOG06429@2157|Archaea,2XU65@28890|Euryarchaeota,23UCP@183963|Halobacteria	183963|Halobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CMS3_k127_1071505_2	391625.PPSIR1_34807	1.102e-141	463.0	COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,4379P@68525|delta/epsilon subdivisions,2X9XU@28221|Deltaproteobacteria,2Z1Y1@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS3_k127_1071505_23	483219.LILAB_25495	1.809e-11	77.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2Z1RM@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1071505_5	941449.dsx2_0032	8.258e-132	440.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2M904@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS3_k127_1071505_4	634956.Geoth_0301	2.743e-133	435.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,1WH9U@129337|Geobacillus	91061|Bacilli	M	Nucleotidyl transferase	rmlA2	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_1071505_11	329726.AM1_0403	3.442e-68	236.0	COG1898@1|root,COG1898@2|Bacteria,1G0QA@1117|Cyanobacteria	1117|Cyanobacteria	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS3_k127_1071505_20	515635.Dtur_1097	1.513e-19	103.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS3_k127_1071505_15	443143.GM18_1411	3.453e-42	160.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,43UY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_1071505_27	795359.TOPB45_0832	0.0001643	51.0	2EAAE@1|root,334ER@2|Bacteria,2GHMY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1071505_17	882378.RBRH_02778	1.434e-34	151.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VPRV@28216|Betaproteobacteria,1K3CH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_1071505_8	1184267.A11Q_2361	8.318e-105	361.0	COG0160@1|root,COG0160@2|Bacteria,1QY1E@1224|Proteobacteria,43C8R@68525|delta/epsilon subdivisions,2MSMC@213481|Bdellovibrionales,2WKTE@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22	ko:K00821,ko:K07250	ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00027,M00028,M00845	R00908,R01648,R02283,R04188,R04475	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_1071505_13	1278073.MYSTI_07060	2.489e-63	247.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,42SUP@68525|delta/epsilon subdivisions,2WPBD@28221|Deltaproteobacteria,2YU07@29|Myxococcales	28221|Deltaproteobacteria	E	N-succinyltransferase beta subunit	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
CMS3_k127_1085407_10	1267533.KB906733_gene3152	4.456e-26	112.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_1085407_7	1382306.JNIM01000001_gene2904	8.363e-40	158.0	COG2320@1|root,COG2320@2|Bacteria,2G94B@200795|Chloroflexi	200795|Chloroflexi	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
CMS3_k127_1085407_6	378806.STAUR_1662	2.357e-48	190.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_1085407_11	1267535.KB906767_gene5521	2.929e-25	116.0	COG1678@1|root,COG1678@2|Bacteria,3Y8TX@57723|Acidobacteria	57723|Acidobacteria	K	Uncharacterized ACR, COG1678	-	-	-	-	-	-	-	-	-	-	-	-	DUF179
CMS3_k127_1085407_2	1121937.AUHJ01000012_gene2718	9.754e-107	358.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,1RSP4@1236|Gammaproteobacteria,469S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	KR domain	hdhA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008709,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0030573,GO:0032787,GO:0033764,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901360,GO:1901575,GO:1901615	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
CMS3_k127_1085407_0	1262914.BN533_02200	1.387e-208	667.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4H1XW@909932|Negativicutes	909932|Negativicutes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS3_k127_1085407_5	525898.Sdel_2224	6.882e-55	208.0	COG0535@1|root,COG0535@2|Bacteria,1PEYS@1224|Proteobacteria,42SNS@68525|delta/epsilon subdivisions,2YQGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_1085407_3	1535287.JP74_20180	8.92e-106	373.0	COG0673@1|root,COG0673@2|Bacteria,1QW91@1224|Proteobacteria,2TU6E@28211|Alphaproteobacteria,3N87P@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_1085407_8	395495.Lcho_1399	3.711e-35	154.0	COG2348@1|root,COG2348@2|Bacteria,1NDJC@1224|Proteobacteria,2W54A@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_1085407_9	216594.MMAR_2322	8.408e-34	150.0	COG4106@1|root,COG4106@2|Bacteria,2H227@201174|Actinobacteria,23CW0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Methyltransferase domain	-	GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_1085407_12	401053.AciPR4_2590	3.631e-19	98.0	COG0463@1|root,COG0463@2|Bacteria,3Y30V@57723|Acidobacteria,2JIJ8@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1085407_1	1267533.KB906735_gene4492	1.824e-115	394.0	COG0399@1|root,COG0399@2|Bacteria,3Y2QT@57723|Acidobacteria,2JKCR@204432|Acidobacteriia	204432|Acidobacteriia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_1085407_4	1246459.KB898353_gene361	1.098e-66	234.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46,4.2.1.76,5.1.3.2	ko:K01710,ko:K01784,ko:K12450	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00293,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_1121647_2	1125863.JAFN01000001_gene3026	5.408e-191	610.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,42MAA@68525|delta/epsilon subdivisions,2WJZC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CMS3_k127_1121647_26	215803.DB30_6871	2.55e-12	81.0	COG1413@1|root,COG1413@2|Bacteria,1N8T9@1224|Proteobacteria,432NM@68525|delta/epsilon subdivisions,2WXPT@28221|Deltaproteobacteria,2YWQZ@29|Myxococcales	28221|Deltaproteobacteria	C	lyase activity	stkY	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121647_4	1122137.AQXF01000003_gene2134	4.285e-157	511.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	glucose sorbosone	MA20_25025	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_1121647_22	1158318.ATXC01000001_gene1263	3.657e-21	101.0	COG0198@1|root,COG0198@2|Bacteria,2G49J@200783|Aquificae	200783|Aquificae	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS3_k127_1121647_23	76114.ebC6	7.624e-21	93.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,2KXDQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS3_k127_1121647_20	1485545.JQLW01000007_gene828	1.823e-31	136.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS3_k127_1121647_12	797210.Halxa_3969	1.534e-55	214.0	COG0169@1|root,arCOG01033@2157|Archaea,2XV7K@28890|Euryarchaeota,23SSE@183963|Halobacteria	183963|Halobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS3_k127_1121647_16	1333998.M2A_2143	6.933e-46	184.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,4BQ8N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS3_k127_1121647_15	379066.GAU_3517	2.745e-49	180.0	COG0783@1|root,COG0783@2|Bacteria	2|Bacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS3_k127_1121647_11	314230.DSM3645_06149	5.139e-57	209.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1121647_19	411684.HPDFL43_02200	5.2e-33	141.0	KOG3539@1|root,32TPV@2|Bacteria,1N2ES@1224|Proteobacteria	1224|Proteobacteria	M	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
CMS3_k127_1121647_5	349521.HCH_01486	1.649e-146	493.0	COG0457@1|root,COG0457@2|Bacteria,1QZ9R@1224|Proteobacteria,1S0PE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_1121647_0	1232683.ADIMK_0681	4.28e-216	681.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	Glutaredoxin,PALP
CMS3_k127_1121647_9	1278073.MYSTI_04882	4.151e-66	233.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_1121647_14	222534.KB893715_gene1744	8.233e-50	190.0	COG1024@1|root,COG1024@2|Bacteria,2HHR6@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	Echdc	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_1121647_25	1297742.A176_05229	1.71e-19	104.0	COG0737@1|root,COG0737@2|Bacteria,1NDBC@1224|Proteobacteria,42V2W@68525|delta/epsilon subdivisions,2WS9M@28221|Deltaproteobacteria,2YV8Z@29|Myxococcales	28221|Deltaproteobacteria	F	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_1121647_21	502025.Hoch_2482	3.424e-21	109.0	COG0737@1|root,COG0737@2|Bacteria,1NDBC@1224|Proteobacteria,42V2W@68525|delta/epsilon subdivisions,2WS9M@28221|Deltaproteobacteria,2YV8Z@29|Myxococcales	28221|Deltaproteobacteria	F	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_1121647_32	1229487.AMYW01000052_gene3176	0.0008231	52.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia,2NVWA@237|Flavobacterium	976|Bacteroidetes	O	Thiol peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_1121647_1	1333998.M2A_0667	8.113e-192	605.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,4BP5Q@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1121647_13	1333998.M2A_0668	4.816e-53	194.0	COG1545@1|root,COG1545@2|Bacteria,1RFF1@1224|Proteobacteria,2UTI3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_1121647_24	1278073.MYSTI_03154	1.17e-20	107.0	COG0484@1|root,COG0484@2|Bacteria,1Q3FY@1224|Proteobacteria,43987@68525|delta/epsilon subdivisions,2X4FA@28221|Deltaproteobacteria,2YYWT@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS3_k127_1121647_3	290397.Adeh_2588	8.893e-189	615.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_1121647_7	316067.Geob_2326	3.958e-81	288.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,43T68@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulation of RNA biosynthetic process	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS3_k127_1121647_18	557598.LHK_03190	3.087e-38	153.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,2KR03@206351|Neisseriales	206351|Neisseriales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS3_k127_1121647_17	1499967.BAYZ01000068_gene1975	9.271e-42	169.0	COG0632@1|root,COG0632@2|Bacteria,2NPR6@2323|unclassified Bacteria	2|Bacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS3_k127_1121647_6	1283300.ATXB01000002_gene3026	8.013e-130	427.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1XDQ4@135618|Methylococcales	135618|Methylococcales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS3_k127_1121647_10	96561.Dole_1367	6.778e-60	238.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
CMS3_k127_1121647_8	1242864.D187_003260	3.967e-81	280.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
CMS3_k127_1121647_29	1232410.KI421421_gene3474	1.182e-07	59.0	COG3215@1|root,COG3215@2|Bacteria,1NW7J@1224|Proteobacteria,43C0W@68525|delta/epsilon subdivisions,2WVFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_1121647_31	483219.LILAB_24935	0.0007324	51.0	COG0457@1|root,COG0457@2|Bacteria	483219.LILAB_24935|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_114127_5	1242864.D187_006518	3.625e-18	98.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_114127_3	479434.Sthe_0323	8.183e-34	151.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_114127_0	1121859.KB890754_gene773	5.285e-111	400.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,47U3H@768503|Cytophagia	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_114127_1	314256.OG2516_03939	1.563e-66	253.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2PF3J@252301|Oceanicola	28211|Alphaproteobacteria	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_114127_4	383372.Rcas_2505	1.84e-24	121.0	COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_114127_2	1121939.L861_13660	1.428e-65	234.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
CMS3_k127_1150749_2	290397.Adeh_3797	2.103e-08	67.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_3797|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1150749_1	1125863.JAFN01000001_gene358	1.676e-53	201.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CMS3_k127_1150749_0	338966.Ppro_2629	3.232e-60	228.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_1151569_4	1127673.GLIP_4078	1.191e-90	317.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF_2,GGDEF,PAS_9,Response_reg
CMS3_k127_1151569_2	710421.Mycch_1749	1.174e-125	417.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,2354S@1762|Mycobacteriaceae	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_1151569_0	1088721.NSU_1480	1.194e-142	465.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1151569_10	1088721.NSU_1479	6.055e-28	130.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_1151569_7	1048339.KB913029_gene3161	3.591e-63	240.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU00@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_1151569_11	1122604.JONR01000003_gene1456	6.978e-22	112.0	COG1309@1|root,COG1309@2|Bacteria,1RIYI@1224|Proteobacteria,1S83E@1236|Gammaproteobacteria,1XA9K@135614|Xanthomonadales	135614|Xanthomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1151569_12	1121918.ARWE01000001_gene322	3.639e-08	65.0	COG2050@1|root,COG2050@2|Bacteria,1MYHD@1224|Proteobacteria,42VUA@68525|delta/epsilon subdivisions,2WRVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1151569_5	502025.Hoch_1681	8.03e-88	325.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,42NGH@68525|delta/epsilon subdivisions,2WKS6@28221|Deltaproteobacteria,2YV7C@29|Myxococcales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	-	-	1.1.1.394,1.1.1.412	ko:K21271,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
CMS3_k127_1151569_1	1313172.YM304_40580	1.256e-135	471.0	COG0243@1|root,COG0243@2|Bacteria,2I8HX@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1151569_14	1110502.TMO_0302	4.439e-05	54.0	COG0346@1|root,COG0346@2|Bacteria,1MZT5@1224|Proteobacteria,2U4GS@28211|Alphaproteobacteria,2JSGD@204441|Rhodospirillales	204441|Rhodospirillales	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
CMS3_k127_1151569_8	626887.J057_11221	1.458e-58	210.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,466YF@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Cation efflux family	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
CMS3_k127_1151569_6	1394178.AWOO02000026_gene5152	6.06e-77	276.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4EI4U@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_1151569_9	1397666.RS24_00090	1.01e-28	121.0	COG3631@1|root,COG3631@2|Bacteria,1N2V5@1224|Proteobacteria,2UMRC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
CMS3_k127_1151569_3	1122917.KB899659_gene5853	1.632e-103	366.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,26S11@186822|Paenibacillaceae	91061|Bacilli	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_1151569_13	749414.SBI_09970	5.166e-06	48.0	COG5285@1|root,COG5285@2|Bacteria,2I8HN@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_1184970_16	246196.MSMEI_3953	6.292e-63	220.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,238S5@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS3_k127_1184970_12	401526.TcarDRAFT_0107	1.063e-69	243.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,4H20C@909932|Negativicutes	909932|Negativicutes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS3_k127_1184970_3	330214.NIDE3182	1.045e-119	399.0	COG0205@1|root,COG0205@2|Bacteria,3J0Y1@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_1184970_1	247633.GP2143_09790	1.407e-165	570.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1184970_10	926569.ANT_02610	2.124e-81	298.0	COG1132@1|root,COG1132@2|Bacteria,2G63W@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1184970_30	425104.Ssed_3845	7.755e-09	65.0	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,2QAAY@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM SH3 type 3 domain protein	ygiM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
CMS3_k127_1184970_19	570967.JMLV01000002_gene1518	3.107e-47	177.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2JS6I@204441|Rhodospirillales	204441|Rhodospirillales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_1184970_25	1125863.JAFN01000001_gene378	7.26e-24	110.0	COG1266@1|root,COG1266@2|Bacteria,1RI59@1224|Proteobacteria,433F0@68525|delta/epsilon subdivisions,2WYHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_1184970_24	382464.ABSI01000010_gene3267	4.053e-25	110.0	COG4067@1|root,COG4067@2|Bacteria,46XTD@74201|Verrucomicrobia,2IWIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS3_k127_1184970_4	1158146.KB907128_gene1799	2.3e-119	392.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1WW1A@135613|Chromatiales	135613|Chromatiales	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS3_k127_1184970_2	1121374.KB891586_gene2742	7.238e-146	475.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RRS7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK,TrkA_C
CMS3_k127_1184970_11	283942.IL2402	4.376e-78	282.0	28JNG@1|root,2Z9ES@2|Bacteria,1N32V@1224|Proteobacteria,1S9AH@1236|Gammaproteobacteria,2QGP2@267893|Idiomarinaceae	1236|Gammaproteobacteria	-	-	pgsW	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1184970_23	283942.IL2401	2.046e-35	145.0	29EG8@1|root,334DW@2|Bacteria,1NFZA@1224|Proteobacteria,1SCN3@1236|Gammaproteobacteria,2QGT7@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Capsule biosynthesis CapC	capC	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
CMS3_k127_1184970_5	283942.IL2400	2.563e-117	394.0	COG0769@1|root,COG0769@2|Bacteria,1QYFB@1224|Proteobacteria,1T3Q5@1236|Gammaproteobacteria,2QGQ5@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Mur ligase middle domain	-	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_M
CMS3_k127_1184970_17	56780.SYN_02762	7.662e-59	233.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
CMS3_k127_1184970_32	1035191.HMPREF0185_01980	0.0002169	53.0	2DBMQ@1|root,2Z9ZP@2|Bacteria,1QVZU@1224|Proteobacteria,2U5JS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
CMS3_k127_1184970_28	925775.XVE_3451	2.597e-12	77.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RYH1@1236|Gammaproteobacteria,1X4YV@135614|Xanthomonadales	135614|Xanthomonadales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_1184970_6	1122603.ATVI01000005_gene3040	2.949e-106	371.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_1184970_22	1121403.AUCV01000025_gene2289	6.325e-36	157.0	COG3216@1|root,COG3216@2|Bacteria,1QEG2@1224|Proteobacteria,42VUY@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
CMS3_k127_1184970_26	246197.MXAN_4398	6.481e-21	107.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	pp2c12	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
CMS3_k127_1184970_9	378806.STAUR_0148	2.454e-82	305.0	COG1033@1|root,COG2834@1|root,COG1033@2|Bacteria,COG2834@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2Z000@29|Myxococcales	28221|Deltaproteobacteria	M	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
CMS3_k127_1184970_27	498211.CJA_3759	2.438e-15	87.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1FIEY@10|Cellvibrio	1236|Gammaproteobacteria	M	Outer membrane lipoprotein-sorting protein	VP1287	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_1184970_13	269799.Gmet_0067	2.635e-68	264.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_1184970_8	338963.Pcar_0241	7.38e-100	346.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,43S8A@69541|Desulfuromonadales	28221|Deltaproteobacteria	JK	16S rRNA methyltransferase RsmB/F	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
CMS3_k127_1184970_14	1121468.AUBR01000005_gene31	9.567e-68	242.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,42FC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS3_k127_1184970_20	644282.Deba_0350	2.713e-45	190.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS3_k127_1184970_0	243231.GSU0128	2.105e-178	589.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS3_k127_1184970_29	1121033.AUCF01000003_gene3449	4.418e-10	74.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2VCDR@28211|Alphaproteobacteria,2JU96@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1184970_21	1206101.AZXC01000010_gene88	3.852e-41	169.0	COG2267@1|root,COG2267@2|Bacteria,2I39T@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	bpoC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
CMS3_k127_1184970_7	398767.Glov_3124	2.56e-104	341.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
CMS3_k127_1184970_18	290397.Adeh_3634	5.758e-57	203.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2YV9Q@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
CMS3_k127_1184970_15	1184607.AUCHE_04_01350	4.589e-64	226.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4F64B@85018|Dermatophilaceae	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
CMS3_k127_1295484_8	1121937.AUHJ01000007_gene1775	6.402e-26	109.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,1RRE0@1236|Gammaproteobacteria,4681B@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
CMS3_k127_1295484_3	1197130.BAFM01000002_gene584	1.792e-58	223.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_1295484_9	745310.G432_12920	3.741e-16	93.0	2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,2UG74@28211|Alphaproteobacteria,2K7DU@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS3_k127_1295484_7	367299.JOEE01000001_gene1522	1.181e-33	134.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4FHCP@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
CMS3_k127_1295484_5	1313172.YM304_26000	1.505e-51	192.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_1295484_2	1394178.AWOO02000005_gene3706	4.022e-98	338.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4EM9F@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1295484_1	1158760.AQXP01000053_gene1468	1.611e-127	430.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_1295484_6	1333998.M2A_2404	2.418e-34	140.0	COG2717@1|root,COG2717@2|Bacteria,1R4CY@1224|Proteobacteria,2U37R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
CMS3_k127_1295484_0	190650.CC_3111	9.163e-150	485.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,2KHQ3@204458|Caulobacterales	204458|Caulobacterales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1295484_4	1382315.JPOI01000001_gene1272	9.973e-54	208.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1WFW5@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
CMS3_k127_1304108_12	1298593.TOL_2735	1.906e-31	134.0	COG1309@1|root,COG1309@2|Bacteria,1N3KN@1224|Proteobacteria,1SA7U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	luxR	-	-	ko:K10913	ko02020,ko02024,ko05111,map02020,map02024,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	TetR_N
CMS3_k127_1304108_6	1229780.BN381_10279	1.601e-100	346.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria	201174|Actinobacteria	Q	diacylglycerol O-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_1304108_8	247633.GP2143_01710	9.372e-80	284.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS3_k127_1304108_7	314230.DSM3645_19443	1.623e-84	319.0	COG2211@1|root,COG2211@2|Bacteria,2IXTA@203682|Planctomycetes	203682|Planctomycetes	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1304108_1	1282876.BAOK01000001_gene984	6.036e-199	638.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	MA20_16305	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1304108_9	443598.AUFA01000002_gene2658	3.207e-63	220.0	COG1545@1|root,COG1545@2|Bacteria,1R44D@1224|Proteobacteria,2U5BU@28211|Alphaproteobacteria,3JY08@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	MA20_16300	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_1304108_4	1550073.JROH01000017_gene401	4.129e-132	444.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1304108_3	1205680.CAKO01000030_gene4841	6.153e-133	453.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2U1CT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_1304108_0	502025.Hoch_6518	2.523e-254	805.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1304108_13	392499.Swit_3325	2.061e-14	86.0	2FHJ6@1|root,33J13@2|Bacteria,1P7ZN@1224|Proteobacteria,2VGXG@28211|Alphaproteobacteria,2KE75@204457|Sphingomonadales	204457|Sphingomonadales	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
CMS3_k127_1304108_10	314345.SPV1_11001	6.964e-54	218.0	COG3658@1|root,COG3658@2|Bacteria	2|Bacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	DHC,Ni_hydr_CYTB
CMS3_k127_1304108_11	1380391.JIAS01000017_gene551	1.118e-37	149.0	COG0457@1|root,COG0457@2|Bacteria,1N0DE@1224|Proteobacteria,2UCGA@28211|Alphaproteobacteria,2JTE7@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
CMS3_k127_1304108_2	1380391.JIAS01000019_gene1121	1.587e-186	616.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_1304108_5	1267535.KB906767_gene966	1.087e-108	365.0	COG2272@1|root,COG2272@2|Bacteria,3Y6S1@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS3_k127_1390172_6	1333998.M2A_2778	7.977e-156	501.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TRM9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_1390172_1	1089552.KI911559_gene439	0.0	1232.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,2JPTT@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS3_k127_1390172_12	570967.JMLV01000012_gene3213	3.237e-125	451.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2JR48@204441|Rhodospirillales	204441|Rhodospirillales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_1390172_5	1123366.TH3_04849	5.293e-176	587.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,2JQ3A@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS3_k127_1390172_4	1002340.AFCF01000011_gene2693	1.313e-183	586.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,34F3I@302485|Phaeobacter	28211|Alphaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_1390172_7	671143.DAMO_1528	2.989e-144	490.0	COG3004@1|root,COG3004@2|Bacteria,2NNWA@2323|unclassified Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS3_k127_1390172_8	768671.ThimaDRAFT_0222	7.299e-142	486.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1WWIW@135613|Chromatiales	135613|Chromatiales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_1390172_16	502025.Hoch_2520	1.796e-15	91.0	2A43J@1|root,30SNM@2|Bacteria,1PBXV@1224|Proteobacteria,43868@68525|delta/epsilon subdivisions,2X3G0@28221|Deltaproteobacteria,2YVXT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1390172_9	243090.RB12393	7.214e-139	464.0	COG3303@1|root,COG3303@2|Bacteria,2J0SN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_1390172_14	671143.DAMO_2937	1.607e-74	282.0	COG0784@1|root,COG3290@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SPOB_a
CMS3_k127_1390172_11	1048339.KB913029_gene2683	1.795e-127	425.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4ESAN@85013|Frankiales	201174|Actinobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS3_k127_1390172_15	1123367.C666_15095	1.06e-23	119.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_4
CMS3_k127_1390172_0	247633.GP2143_09040	0.0	1377.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J8T8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_1390172_10	247633.GP2143_09045	7.439e-128	422.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,1JA4A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_1390172_2	886293.Sinac_1559	8.852e-290	900.0	COG1132@1|root,COG1132@2|Bacteria,2IYCU@203682|Planctomycetes	2|Bacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
CMS3_k127_1390172_3	886293.Sinac_1560	7.639e-275	856.0	COG1132@1|root,COG1132@2|Bacteria,2IYCU@203682|Planctomycetes	2|Bacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
CMS3_k127_1390172_13	1429916.X566_04705	3.356e-114	390.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2TTHT@28211|Alphaproteobacteria,3JTGZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS3_k127_1390172_17	1267535.KB906767_gene2973	9.75e-12	75.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1390172_18	314285.KT71_06349	1.841e-05	53.0	2EXHT@1|root,33QU1@2|Bacteria,1QR5M@1224|Proteobacteria,1SMSS@1236|Gammaproteobacteria,1J7ZE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_1392979_20	1168065.DOK_03638	1.035e-05	48.0	COG1028@1|root,COG1028@2|Bacteria,1R6W8@1224|Proteobacteria,1RY7D@1236|Gammaproteobacteria,1J8ZG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_1392979_6	1121937.AUHJ01000001_gene813	4.032e-108	359.0	COG0451@1|root,COG0451@2|Bacteria,1RGHF@1224|Proteobacteria,1RQTC@1236|Gammaproteobacteria,4696K@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_1392979_8	1121937.AUHJ01000005_gene2226	7.964e-82	297.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,1SWMP@1236|Gammaproteobacteria,46975@72275|Alteromonadaceae	1224|Proteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_1392979_5	1449049.JONW01000005_gene1474	1.485e-108	381.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2VFGV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_1392979_9	42565.FP66_06760	4.095e-80	296.0	COG0391@1|root,COG0391@2|Bacteria,1NW3K@1224|Proteobacteria,1RQP9@1236|Gammaproteobacteria,1XJ3Y@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterised protein family UPF0052	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
CMS3_k127_1392979_17	1205680.CAKO01000029_gene5289	6.505e-38	149.0	COG0824@1|root,COG0824@2|Bacteria,1MZB3@1224|Proteobacteria,2U7CU@28211|Alphaproteobacteria,2JTMB@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS3_k127_1392979_18	1229780.BN381_10319	3.066e-34	149.0	COG2050@1|root,COG2050@2|Bacteria,2I11Y@201174|Actinobacteria,3UXR4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1392979_10	287.DR97_462	5.898e-76	272.0	COG0500@1|root,COG0500@2|Bacteria,1R5D7@1224|Proteobacteria,1T1HU@1236|Gammaproteobacteria,1YKMG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
CMS3_k127_1392979_19	383381.EH30_04405	9.978e-21	101.0	2E1KM@1|root,32WY3@2|Bacteria,1N5IW@1224|Proteobacteria,2UDKY@28211|Alphaproteobacteria,2K734@204457|Sphingomonadales	204457|Sphingomonadales	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
CMS3_k127_1392979_0	395493.BegalDRAFT_0840	0.0	1071.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,4601R@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM aminopeptidase N, Escherichia coli type	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
CMS3_k127_1392979_14	391625.PPSIR1_06733	2.897e-61	220.0	COG0500@1|root,COG2226@2|Bacteria,1PVTT@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_1392979_12	402881.Plav_0854	4.058e-71	277.0	COG0477@1|root,COG2814@2|Bacteria,1RAYJ@1224|Proteobacteria,2U582@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS3_k127_1392979_11	1380394.JADL01000002_gene1736	1.137e-72	251.0	COG0684@1|root,COG0684@2|Bacteria,1MUES@1224|Proteobacteria,2U0IC@28211|Alphaproteobacteria,2JVAX@204441|Rhodospirillales	204441|Rhodospirillales	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS3_k127_1392979_3	1499967.BAYZ01000157_gene583	2.111e-123	405.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_1392979_4	247634.GPB2148_2793	2.486e-110	378.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RXV1@1236|Gammaproteobacteria,1J9T6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS3_k127_1392979_15	1379698.RBG1_1C00001G0769	7.11e-42	176.0	COG3637@1|root,COG3637@2|Bacteria,2NQC8@2323|unclassified Bacteria	2|Bacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
CMS3_k127_1392979_7	1379698.RBG1_1C00001G0768	8.753e-91	310.0	COG3005@1|root,COG3005@2|Bacteria,2NQ90@2323|unclassified Bacteria	2|Bacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	ko:K08354	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko02000	5.A.3.5	-	-	Cytochrome_C554,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1
CMS3_k127_1392979_13	156889.Mmc1_2110	2.873e-62	234.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria	1224|Proteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
CMS3_k127_1392979_1	335543.Sfum_0899	3.12e-186	614.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2MRD0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS3_k127_1392979_16	1227352.C173_26066	2.763e-40	160.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,4HAVD@91061|Bacilli,26QTW@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_1392979_2	1196323.ALKF01000186_gene5730	1.885e-142	461.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,26S4T@186822|Paenibacillaceae	91061|Bacilli	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS3_k127_1395074_21	9978.XP_004590305.1	0.000127	51.0	KOG3544@1|root,KOG3544@2759|Eukaryota,38CJN@33154|Opisthokonta,3BAFZ@33208|Metazoa,3CRU5@33213|Bilateria,487EK@7711|Chordata,4951D@7742|Vertebrata,3J630@40674|Mammalia,35NW9@314146|Euarchontoglires	33208|Metazoa	W	C-terminal tandem repeated domain in type 4 procollagens	COL4A6	GO:0005575,GO:0005576,GO:0005581,GO:0005587,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008150,GO:0009987,GO:0012505,GO:0016043,GO:0030198,GO:0031012,GO:0031974,GO:0032991,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0062023,GO:0070013,GO:0071840,GO:0098642,GO:0098644,GO:0098645,GO:0098651,GO:0099080,GO:0099081	-	ko:K06237	ko04151,ko04510,ko04512,ko04926,ko04933,ko04974,ko05146,ko05165,ko05200,ko05222,map04151,map04510,map04512,map04926,map04933,map04974,map05146,map05165,map05200,map05222	-	-	-	ko00000,ko00001,ko00536,ko04147,ko04516	-	-	-	C4,Collagen
CMS3_k127_1395074_10	604331.AUHY01000085_gene160	8.48e-45	185.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Beta_helix,Peptidase_S74
CMS3_k127_1395074_7	1279017.AQYJ01000029_gene3986	6.956e-93	311.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,1RPYK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
CMS3_k127_1395074_17	1121921.KB898707_gene879	3.433e-21	98.0	COG5331@1|root,COG5331@2|Bacteria,1N7DJ@1224|Proteobacteria,1SCVF@1236|Gammaproteobacteria,2PNY0@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS3_k127_1395074_13	1333998.M2A_2150	3.549e-40	151.0	2A0NG@1|root,32XDJ@2|Bacteria,1N3J7@1224|Proteobacteria,2UD9K@28211|Alphaproteobacteria,4BSDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1395074_11	1185876.BN8_00796	1.365e-42	169.0	COG1680@1|root,COG1680@2|Bacteria,4NHA7@976|Bacteroidetes,47R7U@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CMS3_k127_1395074_12	305700.B447_01516	1.895e-41	155.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,2KX0T@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
CMS3_k127_1395074_20	886293.Sinac_2221	1.19e-06	63.0	COG1073@1|root,COG1073@2|Bacteria,2IXX3@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS3_k127_1395074_9	269482.Bcep1808_6486	6.093e-45	181.0	COG3300@1|root,COG4191@1|root,COG3300@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,1K5WB@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K19661	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9,Response_reg,cNMP_binding
CMS3_k127_1395074_5	345341.KUTG_07999	1.068e-108	360.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4DY22@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_1395074_4	1121937.AUHJ01000008_gene1962	1.144e-127	416.0	COG2141@1|root,COG2141@2|Bacteria,1NXIH@1224|Proteobacteria,1SZ1M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_1395074_1	1246445.ANAY01000020_gene1815	1.729e-160	529.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4EG9V@85012|Streptosporangiales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS3_k127_1395074_0	1030157.AFMP01000009_gene3626	1.248e-174	561.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,2K212@204457|Sphingomonadales	204457|Sphingomonadales	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_1395074_16	215803.DB30_0712	3.468e-24	112.0	COG3000@1|root,COG3000@2|Bacteria,1PK2U@1224|Proteobacteria,437EQ@68525|delta/epsilon subdivisions,2XA2J@28221|Deltaproteobacteria,2YZ75@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_1395074_19	585423.KR49_10265	2.175e-13	77.0	COG1357@1|root,COG1357@2|Bacteria,1G7PE@1117|Cyanobacteria,1H0RN@1129|Synechococcus	1117|Cyanobacteria	T	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_1395074_18	998674.ATTE01000001_gene2609	7.453e-19	89.0	COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,1SEE6@1236|Gammaproteobacteria,4636A@72273|Thiotrichales	72273|Thiotrichales	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K14750	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05440	RC00098	br01602,ko00000,ko00001	-	-	-	Rieske
CMS3_k127_1395074_3	1397666.RS24_01533	2.623e-131	432.0	COG4638@1|root,COG4638@2|Bacteria,1MXZN@1224|Proteobacteria,2U2X0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_1395074_15	301.JNHE01000001_gene509	9.947e-33	142.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1YFHW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS3_k127_1395074_2	207559.Dde_1563	2.957e-142	503.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_1395074_8	1048339.KB913029_gene1045	8.968e-82	287.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4EV45@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_1395074_14	264198.Reut_A0835	4.231e-36	145.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2VRAJ@28216|Betaproteobacteria,1K21D@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
CMS3_k127_1395074_6	298655.KI912266_gene4483	1.237e-94	321.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_1416245_0	1047013.AQSP01000106_gene1773	1.155e-42	173.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS3_k127_1416245_1	1324957.K933_00557	3.192e-24	117.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_1529191_3	1168065.DOK_01629	6.834e-72	248.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1RNWZ@1236|Gammaproteobacteria,1J83F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS3_k127_1529191_1	886293.Sinac_4748	2.341e-93	334.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1529191_2	1265310.CCBD010000061_gene1155	2.247e-86	292.0	2AQ2E@1|root,31F7J@2|Bacteria,2ID84@201174|Actinobacteria,238H3@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1529191_5	1123073.KB899241_gene1978	4.596e-24	118.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS3_k127_1529191_0	1122247.C731_3862	1.129e-159	526.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,233JC@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	fadA5	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1529191_4	1125863.JAFN01000001_gene2523	2.942e-33	135.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_1529191_6	378806.STAUR_6641	7.631e-08	61.0	COG0535@1|root,COG0535@2|Bacteria,1NVXA@1224|Proteobacteria,42NYH@68525|delta/epsilon subdivisions,2WY0S@28221|Deltaproteobacteria,2YYA2@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS3_k127_16006_19	1267535.KB906767_gene4838	1.371e-34	149.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_16006_28	1382359.JIAL01000001_gene84	3.16e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria,2JM74@204432|Acidobacteriia	204432|Acidobacteriia	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_6,TPR_8
CMS3_k127_16006_23	543632.JOJL01000047_gene3341	8.883e-18	98.0	COG0457@1|root,COG0457@2|Bacteria	543632.JOJL01000047_gene3341|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_16006_12	331869.BAL199_15648	3.317e-74	261.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2UJRS@28211|Alphaproteobacteria,4BPVY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Homocysteine S-methyltransferase	yitJ	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS3_k127_16006_29	338966.Ppro_0043	0.0001802	53.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,42SMX@68525|delta/epsilon subdivisions,2X62A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_16006_9	1123240.ATVO01000005_gene2088	1.971e-97	327.0	COG1024@1|root,COG1024@2|Bacteria,1R5CJ@1224|Proteobacteria,2U0GF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_16006_2	439235.Dalk_1526	3.336e-177	599.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS3_k127_16006_15	574376.BAMA_04235	1.062e-60	242.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,4HD2A@91061|Bacilli,1ZDGK@1386|Bacillus	91061|Bacilli	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CMS3_k127_16006_27	1304872.JAGC01000009_gene289	3.64e-09	68.0	COG2755@1|root,COG2755@2|Bacteria,1Q5UQ@1224|Proteobacteria,436PX@68525|delta/epsilon subdivisions,2X1C1@28221|Deltaproteobacteria,2MERH@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_16006_22	1128421.JAGA01000003_gene3091	3.166e-28	135.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_16006_18	797114.C475_12537	1.46e-40	169.0	COG3119@1|root,arCOG02785@2157|Archaea,2XV54@28890|Euryarchaeota,23UWR@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_16006_6	335543.Sfum_1456	1.023e-118	433.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MQ56@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
CMS3_k127_16006_0	690850.Desaf_1775	0.0	1225.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2M817@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS3_k127_16006_8	335543.Sfum_1458	1.546e-100	346.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_16006_1	105422.BBPM01000039_gene766	4.661e-195	630.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,2NGIS@228398|Streptacidiphilus	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_16006_16	1227497.C491_01462	1.37e-56	226.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_16006_10	1048339.KB913029_gene3130	1.237e-92	314.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4ESZE@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_16006_11	1547437.LL06_02990	5.267e-76	270.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,43IAS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CMS3_k127_16006_25	246197.MXAN_4067	1.322e-12	74.0	COG1977@1|root,COG1977@2|Bacteria,1N15U@1224|Proteobacteria,42XSH@68525|delta/epsilon subdivisions,2WTDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_16006_14	358220.C380_13915	6.215e-70	267.0	COG0639@1|root,COG0639@2|Bacteria,1QE1Y@1224|Proteobacteria,2VMRB@28216|Betaproteobacteria,4ACG5@80864|Comamonadaceae	28216|Betaproteobacteria	T	Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_16006_17	43759.JNWK01000072_gene6372	1.155e-53	198.0	COG3741@1|root,COG3741@2|Bacteria,2GSDI@201174|Actinobacteria	201174|Actinobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS3_k127_16006_26	395494.Galf_1932	4.981e-11	67.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2W14Y@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_16006_13	1242864.D187_001443	6.61e-73	278.0	COG0421@1|root,COG0457@1|root,COG0421@2|Bacteria,COG0457@2|Bacteria,1QXA2@1224|Proteobacteria,43C3D@68525|delta/epsilon subdivisions,2WUH2@28221|Deltaproteobacteria,2YYH4@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_16006_4	1415779.JOMH01000001_gene2437	1.188e-147	483.0	COG2031@1|root,COG2031@2|Bacteria,1MV5A@1224|Proteobacteria,1RMTZ@1236|Gammaproteobacteria,1X47G@135614|Xanthomonadales	135614|Xanthomonadales	I	COG2031 Short chain fatty acids transporter	-	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
CMS3_k127_16006_21	1123386.AUIW01000026_gene1405	1.182e-32	142.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	yusZ	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_16006_20	1502724.FF80_03524	7.553e-33	148.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2UB7Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_16006_7	314285.KT71_04360	1.764e-103	381.0	2DB8N@1|root,2Z7S9@2|Bacteria,1PZ8J@1224|Proteobacteria,1S1F6@1236|Gammaproteobacteria,1J5YW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
CMS3_k127_16006_5	933262.AXAM01000049_gene3257	9.347e-139	486.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,42NCG@68525|delta/epsilon subdivisions,2WK7N@28221|Deltaproteobacteria,2MIZV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
CMS3_k127_16006_3	469383.Cwoe_0601	6.38e-170	581.0	COG2114@1|root,COG2909@1|root,COG3899@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc
CMS3_k127_161454_8	1038859.AXAU01000010_gene1787	7.541e-58	222.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2U9BA@28211|Alphaproteobacteria,3JU3W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
CMS3_k127_161454_7	1122194.AUHU01000004_gene1556	1.024e-62	224.0	COG0382@1|root,COG0382@2|Bacteria,1RFNQ@1224|Proteobacteria,1SE0Q@1236|Gammaproteobacteria,4698R@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS3_k127_161454_0	443144.GM21_2427	7.934e-192	625.0	COG1524@1|root,COG1524@2|Bacteria,1P235@1224|Proteobacteria	1224|Proteobacteria	S	proteins of the AP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_161454_4	388051.AUFE01000049_gene3937	1.658e-125	432.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,2VRSG@28216|Betaproteobacteria,1K889@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_161454_2	1122194.AUHU01000004_gene1553	1.339e-141	466.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RQ4T@1236|Gammaproteobacteria,465PK@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SNARE_assoc
CMS3_k127_161454_6	388051.AUFE01000049_gene3940	8.254e-73	257.0	COG1082@1|root,COG1082@2|Bacteria,1QZNV@1224|Proteobacteria	1224|Proteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_161454_1	1134474.O59_003672	1.896e-146	484.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,1RTX9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase, TatD	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
CMS3_k127_161454_5	247634.GPB2148_885	4.707e-103	344.0	COG4689@1|root,COG4689@2|Bacteria,1NSF0@1224|Proteobacteria,1RZ1E@1236|Gammaproteobacteria,1J4ZJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
CMS3_k127_161454_3	247634.GPB2148_2794	1.479e-134	452.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,1RQYQ@1236|Gammaproteobacteria,1J5B4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_161454_9	1122611.KB903997_gene7714	1.276e-54	211.0	COG1804@1|root,COG1804@2|Bacteria,2IB9E@201174|Actinobacteria,4EPHN@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_1667172_2	314285.KT71_06349	1.829e-30	127.0	2EXHT@1|root,33QU1@2|Bacteria,1QR5M@1224|Proteobacteria,1SMSS@1236|Gammaproteobacteria,1J7ZE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_1667172_0	247634.GPB2148_2610	9.717e-113	375.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,1S013@1236|Gammaproteobacteria,1J5C8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1667172_1	575540.Isop_0104	1.432e-40	172.0	COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_1667172_3	330214.NIDE3812	7.596e-16	89.0	COG0457@1|root,COG0457@2|Bacteria,3J17M@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS3_k127_1696634_14	56110.Oscil6304_5208	7.604e-67	243.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_1696634_4	861299.J421_2124	2e-115	381.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_1696634_17	105559.Nwat_0855	2.922e-11	67.0	2EHHF@1|root,33B9C@2|Bacteria,1NM2H@1224|Proteobacteria,1SGI5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1696634_15	880073.Calab_3539	9.308e-33	139.0	COG0589@1|root,COG0589@2|Bacteria,2NPUM@2323|unclassified Bacteria	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_1696634_12	246197.MXAN_5997	5.513e-75	267.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,439QP@68525|delta/epsilon subdivisions,2X537@28221|Deltaproteobacteria,2Z01T@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix domain	dpbF	-	-	-	-	-	-	-	-	-	-	-	HHH_5,HHH_8
CMS3_k127_1696634_7	472759.Nhal_3098	8.671e-82	296.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS3_k127_1696634_8	1231391.AMZF01000031_gene610	7.224e-81	302.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,3T68U@506|Alcaligenaceae	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_1696634_2	472759.Nhal_0357	6.607e-132	449.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXUS@135613|Chromatiales	1236|Gammaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_1696634_9	2340.JV46_13050	3.793e-78	287.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1N12F@1224|Proteobacteria,1S7UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS3_k127_1696634_1	2340.JV46_13040	5.46e-161	534.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J85H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
CMS3_k127_1696634_3	2340.JV46_13030	2.173e-125	434.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,1S7ID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_1696634_18	1121946.AUAX01000006_gene3423	9.998e-05	55.0	2EB78@1|root,3357V@2|Bacteria,2H0NN@201174|Actinobacteria,4DBB7@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1696634_0	716928.AJQT01000077_gene940	5.21e-243	766.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,4BDDU@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Peptidase family M41	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS3_k127_1696634_6	391612.CY0110_27535	1.04e-89	328.0	COG0475@1|root,COG0475@2|Bacteria,1GCKS@1117|Cyanobacteria,3KJCE@43988|Cyanothece	1117|Cyanobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS3_k127_1696634_5	1229780.BN381_290075	1.009e-114	397.0	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Ald_deCOase
CMS3_k127_1696634_13	1229780.BN381_290074	2.567e-71	262.0	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Ald_deCOase
CMS3_k127_1696634_11	1280946.HY29_13415	9.536e-76	262.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2U6HU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_1696634_10	1160718.SU9_32128	1.948e-76	264.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_171061_8	1128421.JAGA01000003_gene3091	3.933e-16	89.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_171061_1	591167.Sfla_0223	1.57e-131	424.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
CMS3_k127_171061_0	391625.PPSIR1_01774	8.291e-282	889.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_171061_6	211114.JOEF01000002_gene4130	3.357e-31	135.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DYKD@85010|Pseudonocardiales	201174|Actinobacteria	GM	epimerase dehydratase	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
CMS3_k127_171061_3	1229780.BN381_630010	6.426e-69	250.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,3UXD2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Phosphate acyltransferases	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_171061_7	1304275.C41B8_13245	6.701e-23	106.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS3_k127_171061_2	1278073.MYSTI_02808	1.732e-69	265.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
CMS3_k127_171061_5	1185652.USDA257_c52960	7.393e-34	153.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
CMS3_k127_171061_4	156889.Mmc1_2685	4.516e-43	183.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
CMS3_k127_1746109_10	1254432.SCE1572_00900	7.499e-09	68.0	COG2192@1|root,COG2755@1|root,COG2192@2|Bacteria,COG2755@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2YYSN@29|Myxococcales	28221|Deltaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_1746109_1	234267.Acid_7336	9.342e-178	574.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_1746109_8	498211.CJA_0478	2.626e-15	90.0	COG0454@1|root,COG0454@2|Bacteria,1QWJ5@1224|Proteobacteria,1T34G@1236|Gammaproteobacteria,1FIB7@10|Cellvibrio	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS3_k127_1746109_7	1226994.AMZB01000123_gene2790	4.292e-39	166.0	COG1231@1|root,COG1231@2|Bacteria,1MUPQ@1224|Proteobacteria,1RZXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amine oxidase	pao	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS3_k127_1746109_4	243233.MCA3015	2.821e-117	391.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1XDW4@135618|Methylococcales	135618|Methylococcales	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_1746109_9	469383.Cwoe_1277	3.381e-10	69.0	COG3226@1|root,COG3226@2|Bacteria,2IMSE@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS3_k127_1746109_5	1380390.JIAT01000009_gene1634	7.916e-115	392.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4CS3E@84995|Rubrobacteria	84995|Rubrobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_1746109_0	565045.NOR51B_1927	5.639e-196	646.0	COG1231@1|root,COG1231@2|Bacteria,1QXX6@1224|Proteobacteria,1T3IZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	1.5.99.6	ko:K00316	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R01914,R01915	RC00053,RC00225	ko00000,ko00001,ko01000	-	-	-	NAD_binding_8
CMS3_k127_1746109_11	102129.Lepto7375DRAFT_2380	1.258e-06	63.0	COG3250@1|root,COG3250@2|Bacteria,1GD73@1117|Cyanobacteria	1117|Cyanobacteria	G	Horizontally Transferred TransMembrane Domain	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
CMS3_k127_1746109_6	1382359.JIAL01000001_gene2776	2.694e-54	209.0	COG3467@1|root,COG3467@2|Bacteria,3Y4HI@57723|Acidobacteria,2JMS6@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS3_k127_1746109_2	1282876.BAOK01000001_gene2617	1.044e-149	490.0	COG0665@1|root,COG0665@2|Bacteria,1Q38Q@1224|Proteobacteria,2TTMM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_1746109_3	1380394.JADL01000009_gene3142	9.025e-139	452.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2JSFS@204441|Rhodospirillales	204441|Rhodospirillales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_1746828_8	338963.Pcar_2692	8.409e-95	319.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,43S8U@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PCRF	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_1746828_0	338966.Ppro_2651	6.721e-200	634.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,43T9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS3_k127_1746828_17	666685.R2APBS1_0702	7.746e-24	117.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1X34B@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS3_k127_1746828_9	338963.Pcar_2950	6.608e-80	280.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,43SFQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	S4 RNA-binding domain	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_1746828_20	1201290.M902_0531	1.861e-21	109.0	COG0484@1|root,COG1426@1|root,COG0484@2|Bacteria,COG1426@2|Bacteria,1NCYU@1224|Proteobacteria,42WS1@68525|delta/epsilon subdivisions,2MT9U@213481|Bdellovibrionales,2WSDX@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,HTH_25
CMS3_k127_1746828_10	589865.DaAHT2_2396	5.233e-74	263.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2MKRR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
CMS3_k127_1746828_11	1278073.MYSTI_04586	3.144e-68	241.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria	1224|Proteobacteria	L	HNH endonuclease	MA20_20605	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS3_k127_1746828_4	644968.DFW101_0305	7.474e-111	386.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2M7TJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS3_k127_1746828_1	269799.Gmet_3192	3.147e-155	516.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS3_k127_1746828_14	1123371.ATXH01000027_gene160	6.958e-29	127.0	COG0261@1|root,COG0261@2|Bacteria,2GHY6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS3_k127_1746828_13	56780.SYN_01352	2.971e-29	118.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS3_k127_1746828_5	1267535.KB906767_gene4592	2.711e-100	340.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria,2JI5G@204432|Acidobacteriia	204432|Acidobacteriia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS3_k127_1746828_7	1458357.BG58_39995	4.149e-96	342.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,1K327@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS3_k127_1746828_12	1125863.JAFN01000001_gene292	2.39e-44	183.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
CMS3_k127_1746828_18	1400520.LFAB_06635	6.604e-22	109.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS3_k127_1746828_2	1122137.AQXF01000003_gene1930	9.064e-151	510.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2TS6R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS3_k127_1746828_16	266117.Rxyl_1623	6.794e-25	115.0	COG1040@1|root,COG1040@2|Bacteria,2HP3J@201174|Actinobacteria,4CQES@84995|Rubrobacteria	84995|Rubrobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS3_k127_1746828_3	1211115.ALIQ01000018_gene2086	5.375e-147	480.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,3NA8R@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
CMS3_k127_1746828_23	1038866.KB902768_gene4753	4.963e-07	61.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3K6MV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1
CMS3_k127_1746828_19	323848.Nmul_A2401	1.11e-21	111.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_1746828_6	1380356.JNIK01000016_gene3679	7.146e-97	327.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria,4ESFU@85013|Frankiales	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_1746828_22	640512.BC1003_4678	3.068e-14	84.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1R93B@1224|Proteobacteria,2VPEV@28216|Betaproteobacteria,1KHUF@119060|Burkholderiaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K07677	ko02020,ko02026,map02020,map02026	M00474	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_1746828_15	439235.Dalk_4322	5.878e-27	123.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2MJDG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_1774879_12	335543.Sfum_3096	1.312e-39	151.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2MQA0@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
CMS3_k127_1774879_15	1297742.A176_04110	3.776e-12	72.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,431UR@68525|delta/epsilon subdivisions,2WWZQ@28221|Deltaproteobacteria,2YU65@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
CMS3_k127_1774879_11	290397.Adeh_0734	1.985e-45	177.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_1774879_0	1125863.JAFN01000001_gene2270	1.58e-316	993.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_1774879_3	546271.Selsp_1030	6.05e-89	336.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H2TK@909932|Negativicutes	909932|Negativicutes	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS3_k127_1774879_10	1237149.C900_03143	1.064e-48	181.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,47R6S@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
CMS3_k127_1774879_13	1279009.ADICEAN_02215	1.587e-31	138.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,47QMU@768503|Cytophagia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CMS3_k127_1774879_16	699246.HMPREF0868_1580	1.794e-08	65.0	COG0510@1|root,COG4750@1|root,COG0510@2|Bacteria,COG4750@2|Bacteria,1TRCJ@1239|Firmicutes,24BS7@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_1_2,Choline_kinase,HTH_24,NTP_transf_3
CMS3_k127_1774879_8	1122613.ATUP01000001_gene129	1.374e-66	256.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,43WIG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS3_k127_1774879_7	744980.TRICHSKD4_0748	4.561e-71	250.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS3_k127_1774879_4	43989.cce_3591	1.912e-84	301.0	COG0528@1|root,COG0528@2|Bacteria,1G0CR@1117|Cyanobacteria,3KGRG@43988|Cyanothece	1117|Cyanobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_1774879_9	338963.Pcar_1918	4.629e-54	209.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,43SFD@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosome recycling factor	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS3_k127_1774879_5	264732.Moth_1038	3.356e-82	280.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS3_k127_1774879_2	1121405.dsmv_2171	4.086e-110	379.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,2MIFC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS3_k127_1774879_6	1242864.D187_003828	2.595e-78	295.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS3_k127_1774879_14	679201.HMPREF9334_00070	3.308e-27	121.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4H47Z@909932|Negativicutes	909932|Negativicutes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_1774879_1	1125863.JAFN01000001_gene2480	5.564e-134	436.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS3_k127_1808264_3	305700.B447_00185	8.898e-11	75.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2VH3J@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3
CMS3_k127_1808264_1	1476583.DEIPH_ctg004orf0092	3.966e-28	131.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Esterase
CMS3_k127_1808264_2	1048339.KB913029_gene4441	1.985e-13	85.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_1808264_0	278963.ATWD01000001_gene2369	4.837e-256	843.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_1823879_5	1123360.thalar_00055	3.956e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8
CMS3_k127_1823879_1	324925.Ppha_0561	6.672e-45	174.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS3_k127_1823879_4	1173027.Mic7113_5229	1.518e-06	58.0	COG1376@1|root,COG1376@2|Bacteria,1G74K@1117|Cyanobacteria,1HB9C@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS3_k127_1823879_3	880072.Desac_1311	1.244e-09	72.0	COG0457@1|root,COG0457@2|Bacteria,1QTM2@1224|Proteobacteria,43F3J@68525|delta/epsilon subdivisions,2X39C@28221|Deltaproteobacteria,2MSHJ@213462|Syntrophobacterales	880072.Desac_1311|-	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1823879_2	926569.ANT_23150	1.263e-30	136.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1823879_0	1120983.KB894574_gene870	2.207e-76	278.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2U48V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
CMS3_k127_186552_4	1089544.KB912942_gene4642	4.722e-07	51.0	COG0640@1|root,COG0640@2|Bacteria,2IHS2@201174|Actinobacteria,4EBKY@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_186552_0	909663.KI867150_gene213	1.182e-124	421.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_186552_3	1232410.KI421421_gene3694	1.838e-38	160.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_186552_2	1089552.KI911559_gene2124	5.819e-95	327.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria,2JQSP@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_186552_1	1121033.AUCF01000028_gene376	1.531e-98	331.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,2JQ2Y@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_186636_5	1219035.NT2_05_04640	6.272e-111	374.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2K2DM@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
CMS3_k127_186636_14	1380356.JNIK01000021_gene4444	2.484e-26	114.0	COG3631@1|root,COG3631@2|Bacteria,2IJ87@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_186636_7	1123023.JIAI01000001_gene5987	1.406e-102	352.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4DYZQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_186636_2	1123320.KB889585_gene1872	6.244e-170	547.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_186636_8	1123320.KB889585_gene1873	2.748e-89	306.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_186636_6	1121374.KB891575_gene1051	4.57e-108	359.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_186636_4	1030157.AFMP01000009_gene3656	4.075e-113	381.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,1QV6D@1224|Proteobacteria,2TTB1@28211|Alphaproteobacteria,2K8G7@204457|Sphingomonadales	204457|Sphingomonadales	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_186636_1	1030157.AFMP01000009_gene3655	3.544e-174	560.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,2K3PM@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_186636_11	28042.GU90_07625	1.431e-46	179.0	COG1024@1|root,COG1024@2|Bacteria,2HEIS@201174|Actinobacteria,4DZPT@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_186636_12	644548.SCNU_09894	1.076e-38	150.0	COG5517@1|root,COG5517@2|Bacteria,2IFNT@201174|Actinobacteria,4GES2@85026|Gordoniaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_186636_10	1206737.BAGF01000075_gene4695	1.596e-81	301.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4FU6M@85025|Nocardiaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.384	ko:K13327	ko00523,ko01130,map00523,map01130	M00801,M00802	R05526	RC00897	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_186636_0	1282876.BAOK01000001_gene3037	1.119e-178	574.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TUFX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_186636_3	909613.UO65_5595	1.429e-128	438.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4DYBI@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	2.6.1.106	ko:K13310	ko00523,ko01130,map00523,map01130	M00797	R06426	RC00006,RC01514	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_186636_9	237368.SCABRO_04050	2.27e-82	287.0	COG0673@1|root,COG0673@2|Bacteria,2IYW6@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
CMS3_k127_186636_15	1206729.BAFZ01000060_gene3596	9.833e-15	81.0	COG1141@1|root,COG1141@2|Bacteria,2GS47@201174|Actinobacteria,4G3V5@85025|Nocardiaceae	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13,Fer4_15
CMS3_k127_186636_13	1219035.NT2_04_00110	3.141e-29	124.0	COG4308@1|root,COG4308@2|Bacteria,1RJ3T@1224|Proteobacteria,2UAH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Limonene-1,2-epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LEH
CMS3_k127_1867309_3	338963.Pcar_1732	7.825e-135	434.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,43V2E@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_1867309_5	215803.DB30_2511	1.94e-113	372.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria,2YU5U@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS3_k127_1867309_0	251221.35214644	1.862e-220	706.0	COG1166@1|root,COG1166@2|Bacteria,1G1C4@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CMS3_k127_1867309_4	55529.EKX55560	9.494e-119	414.0	COG0124@1|root,KOG1936@2759|Eukaryota	2759|Eukaryota	J	Histidyl-trna synthetase	-	GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	3.6.4.13,6.1.1.21	ko:K01892,ko:K14442	ko00970,ko03018,map00970,map03018	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03019	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS3_k127_1867309_24	864051.BurJ1DRAFT_2359	2.275e-07	63.0	COG1621@1|root,COG4412@1|root,COG1621@2|Bacteria,COG4412@2|Bacteria,1MWWV@1224|Proteobacteria	1224|Proteobacteria	O	Zinc metalloprotease (Elastase)	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
CMS3_k127_1867309_14	391623.TERMP_00251	8.561e-51	210.0	COG2820@1|root,arCOG01324@2157|Archaea,2XSWN@28890|Euryarchaeota,243RY@183968|Thermococci	183968|Thermococci	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	-	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_1867309_21	225937.HP15_4020	4.028e-15	91.0	COG3103@1|root,COG3103@2|Bacteria,1QXFZ@1224|Proteobacteria,1RPAR@1236|Gammaproteobacteria,465YC@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
CMS3_k127_1867309_22	1000565.METUNv1_03702	8.27e-14	87.0	COG3103@1|root,COG3103@2|Bacteria,1QXFZ@1224|Proteobacteria,2WI8T@28216|Betaproteobacteria,2KZQQ@206389|Rhodocyclales	206389|Rhodocyclales	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1867309_26	1415778.JQMM01000001_gene2188	7.048e-05	55.0	2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1RWA9@1236|Gammaproteobacteria,1J6XV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
CMS3_k127_1867309_11	1340493.JNIF01000003_gene3270	2.838e-58	217.0	COG5002@1|root,COG5002@2|Bacteria,3Y99C@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_1867309_9	401053.AciPR4_2162	4.333e-63	229.0	COG0745@1|root,COG0745@2|Bacteria,3Y4FA@57723|Acidobacteria,2JJ3P@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1867309_10	1123258.AQXZ01000018_gene860	1.808e-61	220.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4FW8M@85025|Nocardiaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
CMS3_k127_1867309_23	1499967.BAYZ01000118_gene3298	3.44e-13	82.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
CMS3_k127_1867309_6	926550.CLDAP_39110	1.02e-108	394.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1867309_7	357808.RoseRS_2972	9.152e-97	331.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1867309_17	1184267.A11Q_1512	2.801e-34	150.0	COG3303@1|root,COG3303@2|Bacteria,1QY22@1224|Proteobacteria,43C9D@68525|delta/epsilon subdivisions,2MTWU@213481|Bdellovibrionales,2WQ1C@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_1867309_1	861299.J421_3630	1.208e-182	608.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
CMS3_k127_1867309_2	379066.GAU_2035	1.447e-154	500.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS3_k127_1867309_18	379066.GAU_2034	2.939e-24	119.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS3_k127_1867309_19	861299.J421_3627	1.003e-22	106.0	COG2010@1|root,COG2010@2|Bacteria,1ZTPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_1867309_15	861299.J421_3626	1.657e-45	186.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1867309_25	675635.Psed_0110	3.047e-07	63.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4E02H@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_1867309_20	1231391.AMZF01000001_gene2847	1.663e-17	94.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2WBZT@28216|Betaproteobacteria,3T70G@506|Alcaligenaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1867309_16	1238182.C882_0839	1.294e-42	166.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,2JRXM@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_1867309_8	1353531.AZNX01000001_gene2199	1.097e-77	292.0	COG0591@1|root,COG0784@1|root,COG4251@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG4251@2|Bacteria,1QTSW@1224|Proteobacteria,2TW0C@28211|Alphaproteobacteria,4BNR3@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
CMS3_k127_1867309_13	391625.PPSIR1_21689	1.212e-51	193.0	COG0406@1|root,COG0406@2|Bacteria,1RA6X@1224|Proteobacteria	1224|Proteobacteria	G	phosphoglycerate	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS3_k127_1867309_12	1231391.AMZF01000037_gene583	9.515e-53	189.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VI5X@28216|Betaproteobacteria,3T6F3@506|Alcaligenaceae	28216|Betaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS3_k127_1963236_0	1254432.SCE1572_41005	1.889e-54	208.0	COG2706@1|root,COG3391@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,1RB92@1224|Proteobacteria,43CMY@68525|delta/epsilon subdivisions,2X7V4@28221|Deltaproteobacteria,2YXBK@29|Myxococcales	28221|Deltaproteobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_1963236_1	748247.AZKH_1863	2.459e-10	62.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,2KV0M@206389|Rhodocyclales	206389|Rhodocyclales	C	NADH flavin	abmA	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
CMS3_k127_1975284_3	686340.Metal_2187	1.725e-28	124.0	COG2303@1|root,COG2303@2|Bacteria,1RH5U@1224|Proteobacteria,1S60X@1236|Gammaproteobacteria,1XGVN@135618|Methylococcales	135618|Methylococcales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1975284_5	1423144.Gal_01469	3.97e-14	75.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2UJIU@28211|Alphaproteobacteria,34G0A@302485|Phaeobacter	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS3_k127_1975284_1	344747.PM8797T_03349	4.341e-212	670.0	COG0527@1|root,COG0527@2|Bacteria,2IY8N@203682|Planctomycetes	203682|Planctomycetes	E	aspartate kinase, monofunctional class	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_1975284_6	525897.Dbac_1109	3.22e-06	57.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_1975284_2	640081.Dsui_3307	9.204e-38	154.0	COG2863@1|root,COG2863@2|Bacteria,1R6DK@1224|Proteobacteria,2VNV6@28216|Betaproteobacteria,2KUAF@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_1975284_4	1121013.P873_12065	2.211e-28	128.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,1RQ8C@1236|Gammaproteobacteria,1X63R@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_1975284_0	1333998.M2A_1689	3.706e-284	921.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4BPAA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_1988833_1	1333998.M2A_2211	1.714e-195	623.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,4BT9B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS3_k127_1988833_21	1123508.JH636450_gene7073	1.443e-07	61.0	COG0622@1|root,COG0622@2|Bacteria,2IZQH@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS3_k127_1988833_6	402881.Plav_0849	3.196e-108	359.0	COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,2TTJ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	MA20_32365	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_1988833_3	1192034.CAP_8987	3.41e-171	563.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,43A4M@68525|delta/epsilon subdivisions,2WYKE@28221|Deltaproteobacteria,2Z0NN@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_1988833_18	861299.J421_0551	1.686e-21	99.0	2DNQD@1|root,32YJR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
CMS3_k127_1988833_15	1121937.AUHJ01000007_gene1847	8.736e-41	166.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,1S1Y5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_1988833_2	28377.ENSACAP00000002328	6.189e-194	623.0	COG0028@1|root,KOG1185@2759|Eukaryota,38EFU@33154|Opisthokonta,3BGF6@33208|Metazoa,3CUC0@33213|Bilateria,4815T@7711|Chordata,494NR@7742|Vertebrata	33208|Metazoa	EH	fatty acid alpha-oxidation	HACL1	GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681	-	ko:K12261	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_1988833_10	45351.EDO37815	3.219e-62	226.0	COG0673@1|root,KOG2742@2759|Eukaryota,39JIP@33154|Opisthokonta,3CQYJ@33208|Metazoa	33208|Metazoa	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_1988833_17	402881.Plav_2495	2.219e-27	129.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2U5AR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	MA20_00485	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
CMS3_k127_1988833_9	1127673.GLIP_0983	4.303e-68	240.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,1RZZS@1236|Gammaproteobacteria,4666H@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N_3
CMS3_k127_1988833_5	247634.GPB2148_479	1.869e-128	429.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1J4GG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_1988833_20	204669.Acid345_4277	2.638e-16	91.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_4277|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1988833_12	118168.MC7420_2791	8.06e-55	216.0	COG4313@1|root,COG4313@2|Bacteria,1G150@1117|Cyanobacteria	1117|Cyanobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS3_k127_1988833_16	278957.ABEA03000176_gene2841	3.696e-35	145.0	COG1999@1|root,COG1999@2|Bacteria,46W2T@74201|Verrucomicrobia,3K80B@414999|Opitutae	414999|Opitutae	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
CMS3_k127_1988833_8	1125863.JAFN01000001_gene3410	1.762e-81	282.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS3_k127_1988833_14	926550.CLDAP_28350	1.121e-45	192.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
CMS3_k127_1988833_4	529818.AMSG_11506T0	2.923e-136	488.0	29QRV@1|root,2RX97@2759|Eukaryota	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_1988833_11	1144275.COCOR_02955	1.136e-60	218.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,43A6F@68525|delta/epsilon subdivisions,2XA3X@28221|Deltaproteobacteria,2Z18A@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
CMS3_k127_1988833_7	1229172.JQFA01000002_gene3590	1.728e-98	333.0	COG0614@1|root,COG0614@2|Bacteria,1G1W1@1117|Cyanobacteria,1H7T1@1150|Oscillatoriales	1117|Cyanobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_1988833_13	502025.Hoch_0349	1.145e-50	190.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.11,5.4.2.12	ko:K01834,ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS3_k127_1988833_0	84531.JMTZ01000095_gene438	3.05e-309	970.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1X46E@135614|Xanthomonadales	135614|Xanthomonadales	L	Helicase	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS3_k127_2016506_28	1323663.AROI01000008_gene2567	8.33e-33	134.0	COG2823@1|root,COG2823@2|Bacteria,1RHX0@1224|Proteobacteria,1S742@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS3_k127_2016506_22	583355.Caka_1597	9.408e-41	170.0	COG0668@1|root,COG0668@2|Bacteria,46UFI@74201|Verrucomicrobia,3K8BZ@414999|Opitutae	414999|Opitutae	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS3_k127_2016506_36	1123237.Salmuc_02631	1.103e-13	85.0	COG2010@1|root,COG2010@2|Bacteria,1QXW0@1224|Proteobacteria,2TXCX@28211|Alphaproteobacteria	2|Bacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_2016506_43	330214.NIDE2674	1.612e-05	58.0	COG0614@1|root,COG0614@2|Bacteria,3J173@40117|Nitrospirae	40117|Nitrospirae	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_2016506_39	261292.Nit79A3_3314	4.239e-11	76.0	COG5549@1|root,COG5549@2|Bacteria,1PE84@1224|Proteobacteria,2WC16@28216|Betaproteobacteria,37458@32003|Nitrosomonadales	28216|Betaproteobacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016506_23	1440774.Y900_025690	1.982e-39	169.0	COG3000@1|root,COG3000@2|Bacteria,2HR3N@201174|Actinobacteria,234PY@1762|Mycobacteriaceae	201174|Actinobacteria	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_2016506_30	1242864.D187_005725	1.148e-25	116.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT,Paired_CXXCH_1
CMS3_k127_2016506_18	671143.DAMO_0822	3.446e-59	234.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
CMS3_k127_2016506_3	671143.DAMO_0821	2.537e-121	415.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
CMS3_k127_2016506_29	1379698.RBG1_1C00001G0781	7.444e-28	119.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
CMS3_k127_2016506_42	1144275.COCOR_00971	1.746e-07	64.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_2016506_24	1232410.KI421426_gene1479	2.668e-38	158.0	COG3900@1|root,COG3900@2|Bacteria,1RKQP@1224|Proteobacteria,42US2@68525|delta/epsilon subdivisions,2WQT6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted periplasmic protein (DUF2092)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092
CMS3_k127_2016506_9	1121127.JAFA01000010_gene4032	1.053e-96	324.0	COG0625@1|root,COG0625@2|Bacteria,1RHXQ@1224|Proteobacteria,2W2WE@28216|Betaproteobacteria	28216|Betaproteobacteria	O	glutathione transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016506_21	459495.SPLC1_S030200	2.397e-43	170.0	COG1073@1|root,COG1073@2|Bacteria,1G60G@1117|Cyanobacteria,1HB4N@1150|Oscillatoriales	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_2016506_15	392499.Swit_1831	5.655e-64	239.0	COG1024@1|root,COG1024@2|Bacteria,1RC0E@1224|Proteobacteria,2UCQV@28211|Alphaproteobacteria,2K453@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2016506_17	596153.Alide_3296	3.424e-60	217.0	COG1024@1|root,COG1024@2|Bacteria,1MWBI@1224|Proteobacteria,2VJZ6@28216|Betaproteobacteria,4AG70@80864|Comamonadaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2016506_8	298654.FraEuI1c_2679	1.507e-99	331.0	COG3804@1|root,COG3804@2|Bacteria,2IA3Y@201174|Actinobacteria	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
CMS3_k127_2016506_0	1144275.COCOR_04081	1.691e-207	698.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS3_k127_2016506_25	243233.MCA2132	5.595e-38	164.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XGD1@135618|Methylococcales	135618|Methylococcales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS3_k127_2016506_35	443218.AS9A_2639	7.348e-17	94.0	COG1309@1|root,COG1309@2|Bacteria,2GP91@201174|Actinobacteria,23651@1762|Mycobacteriaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_2016506_20	765952.PUV_25580	2.778e-50	190.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_2016506_31	1227487.C474_03855	1.278e-25	115.0	arCOG11838@1|root,arCOG11838@2157|Archaea,2Y03W@28890|Euryarchaeota,23XVJ@183963|Halobacteria	183963|Halobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CMS3_k127_2016506_14	1280950.HJO_16100	3.982e-66	237.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2U31Y@28211|Alphaproteobacteria	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2016506_44	1122939.ATUD01000001_gene53	2.401e-05	57.0	28KB1@1|root,2Z9Y5@2|Bacteria,2HQ2G@201174|Actinobacteria,4CRIU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016506_40	1112214.AHIS01000101_gene1663	1.566e-09	70.0	COG1807@1|root,COG1807@2|Bacteria,1RM6R@1224|Proteobacteria,2USPP@28211|Alphaproteobacteria,2K8AC@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2016506_10	1122611.KB903950_gene6404	2.117e-88	312.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EG8B@85012|Streptosporangiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_2016506_19	1313172.YM304_38590	9.488e-53	200.0	COG4195@1|root,COG4195@2|Bacteria,2GU51@201174|Actinobacteria	201174|Actinobacteria	C	Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2,GGACT,Gamma_PGA_hydro
CMS3_k127_2016506_5	113395.AXAI01000006_gene1825	3.153e-111	378.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2016506_41	391625.PPSIR1_24954	2.971e-08	55.0	COG1225@1|root,COG1225@2|Bacteria,1NN23@1224|Proteobacteria,42XJF@68525|delta/epsilon subdivisions,2WTAE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	AhpC/TSA antioxidant enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
CMS3_k127_2016506_46	248742.XP_005649951.1	0.0003381	48.0	KOG4498@1|root,KOG4498@2759|Eukaryota,37Q8T@33090|Viridiplantae,34M88@3041|Chlorophyta	3041|Chlorophyta	S	AhpC/TSA antioxidant enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
CMS3_k127_2016506_2	1123023.JIAI01000019_gene2233	7.858e-192	618.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria,4EASN@85010|Pseudonocardiales	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016506_32	1313172.YM304_14670	2.889e-25	122.0	2E6FA@1|root,3312Q@2|Bacteria,2GUWJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016506_34	2074.JNYD01000003_gene3586	8.595e-18	85.0	2DS3D@1|root,33EC4@2|Bacteria,2GXNR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016506_11	1219045.BV98_003436	1.178e-87	301.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2K2BK@204457|Sphingomonadales	204457|Sphingomonadales	Q	taurine catabolism dioxygenase	-	-	1.14.11.17	ko:K03119,ko:K22303	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_2016506_12	160799.PBOR_26515	3.123e-72	261.0	COG2211@1|root,COG2211@2|Bacteria,1U037@1239|Firmicutes,4HBZK@91061|Bacilli,26YTA@186822|Paenibacillaceae	91061|Bacilli	G	MFS/sugar transport protein	yihO3	-	-	ko:K03292,ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.5	-	-	MFS_2
CMS3_k127_2016506_4	395019.Bmul_0762	1.974e-113	382.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VNZF@28216|Betaproteobacteria,1K34S@119060|Burkholderiaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	caiB	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2016506_16	1057002.KB905370_gene1251	1.016e-63	227.0	COG5588@1|root,COG5588@2|Bacteria,1PZHC@1224|Proteobacteria,2TVVV@28211|Alphaproteobacteria,4BBPN@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS3_k127_2016506_6	1463858.JOHR01000001_gene6186	4.58e-106	379.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	2|Bacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
CMS3_k127_2016506_37	290399.Arth_1924	8.669e-13	78.0	2DB8V@1|root,2Z7SX@2|Bacteria,2IA72@201174|Actinobacteria	201174|Actinobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	1.1.99.3	ko:K06152	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	Gluconate_2-dh3
CMS3_k127_2016506_13	1348663.KCH_16260	2.072e-69	255.0	COG3250@1|root,COG3250@2|Bacteria,2I952@201174|Actinobacteria,2M46T@2063|Kitasatospora	201174|Actinobacteria	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
CMS3_k127_2016506_1	1123024.AUII01000001_gene3062	4.646e-198	634.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria,4E0RS@85010|Pseudonocardiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	pamO	-	1.14.13.22,1.14.13.92	ko:K03379,ko:K18229	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3,FMO-like,Pyr_redox_2,Pyr_redox_3
CMS3_k127_2016506_33	1121403.AUCV01000030_gene2737	4.297e-24	114.0	2DSDS@1|root,33FPE@2|Bacteria,1Q5RQ@1224|Proteobacteria,431PE@68525|delta/epsilon subdivisions,2WWY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016506_26	523791.Kkor_1008	7.764e-36	151.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1S07F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_2016506_38	935866.JAER01000050_gene865	2.709e-11	76.0	COG3591@1|root,COG3591@2|Bacteria,2I3KX@201174|Actinobacteria,4DWWM@85009|Propionibacteriales	201174|Actinobacteria	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_2016506_7	350054.Mflv_3008	1.464e-101	337.0	COG2267@1|root,COG2267@2|Bacteria,2IDAD@201174|Actinobacteria,236SM@1762|Mycobacteriaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_2024782_5	298654.FraEuI1c_3304	5.554e-132	430.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_2024782_13	1030157.AFMP01000065_gene1128	9.383e-19	96.0	COG1309@1|root,COG1309@2|Bacteria,1NM2A@1224|Proteobacteria,2VE44@28211|Alphaproteobacteria,2K3MQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2024782_1	1160137.KB907307_gene3379	6.712e-162	530.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FU9T@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2024782_10	1296416.JACB01000010_gene1524	1.318e-23	118.0	COG2834@1|root,COG3391@1|root,COG2834@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,1I9S0@117743|Flavobacteriia	976|Bacteroidetes	M	Cadherin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,NHL
CMS3_k127_2024782_11	1340493.JNIF01000003_gene4245	2.346e-20	106.0	COG3386@1|root,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_2024782_14	1078020.KEK_18013	4.509e-13	76.0	COG5470@1|root,COG5470@2|Bacteria,2IR5P@201174|Actinobacteria,23AVH@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS3_k127_2024782_12	1528098.NOVO_04830	1.734e-19	104.0	COG5424@1|root,COG5424@2|Bacteria,1PV6D@1224|Proteobacteria,2V6N7@28211|Alphaproteobacteria,47F6F@766|Rickettsiales	766|Rickettsiales	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
CMS3_k127_2024782_4	298653.Franean1_4294	7.776e-140	454.0	COG1960@1|root,COG1960@2|Bacteria,2GKYN@201174|Actinobacteria,4EUHS@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2024782_9	298655.KI912266_gene5912	8.088e-42	177.0	COG1960@1|root,COG1960@2|Bacteria,2GM6Q@201174|Actinobacteria,4EWEI@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
CMS3_k127_2024782_2	298653.Franean1_6912	3.826e-155	492.0	COG1024@1|root,COG1024@2|Bacteria,2I9QY@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.18	ko:K20765	-	-	-	-	ko00000,ko01000	-	-	-	ECH_1
CMS3_k127_2024782_6	1172185.KB911512_gene5205	2.2e-100	334.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4FUZE@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2024782_0	1150599.MPHLEI_19030	5.061e-173	556.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,232NT@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2024782_8	1056816.JAFQ01000004_gene4980	7.351e-65	235.0	COG1960@1|root,COG1960@2|Bacteria,2HQGI@201174|Actinobacteria,4FW8Y@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
CMS3_k127_2024782_7	298654.FraEuI1c_5408	3.223e-94	323.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4ES18@85013|Frankiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain protein	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS3_k127_2024782_3	298653.Franean1_3309	1.535e-140	452.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2096169_25	1356852.N008_12450	5.571e-41	177.0	COG1033@1|root,COG1033@2|Bacteria,4NKTD@976|Bacteroidetes,47UF5@768503|Cytophagia	976|Bacteroidetes	S	Patched family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_2096169_24	483219.LILAB_29110	2.497e-44	178.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUB5@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2096169_12	1219035.NT2_01_05550	1.249e-82	287.0	28J0M@1|root,2Z8XS@2|Bacteria,1RKDT@1224|Proteobacteria,2U9QW@28211|Alphaproteobacteria,2KA4X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2096169_10	290397.Adeh_4264	6.076e-92	315.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WK5Q@28221|Deltaproteobacteria,2Z31B@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS3_k127_2096169_32	426355.Mrad2831_2091	2.501e-14	85.0	COG2242@1|root,COG2242@2|Bacteria,1R06P@1224|Proteobacteria,2TYKJ@28211|Alphaproteobacteria,1JWK2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_2096169_26	1122604.JONR01000010_gene3827	2.51e-36	147.0	COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,1RYNK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_2096169_16	89187.ISM_09776	2.699e-68	265.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,46PWQ@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS3_k127_2096169_30	269799.Gmet_1607	1.23e-17	87.0	COG2201@1|root,COG2201@2|Bacteria,1N3V6@1224|Proteobacteria	1224|Proteobacteria	T	cheY-homologous receiver domain	cheY-4	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_2096169_34	1410625.JHWK01000003_gene1931	4.055e-07	64.0	COG1406@1|root,COG1406@2|Bacteria,1V46M@1239|Firmicutes,24B3C@186801|Clostridia,27TPV@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
CMS3_k127_2096169_9	1382306.JNIM01000001_gene2032	4.06e-104	359.0	COG2272@1|root,COG2272@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS3_k127_2096169_19	671143.DAMO_0961	7.856e-51	198.0	COG1538@1|root,COG1538@2|Bacteria,2NPI8@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_2096169_8	338963.Pcar_1715	8.933e-106	385.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,43SBG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
CMS3_k127_2096169_0	1121374.KB891590_gene1659	0.0	1298.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS3_k127_2096169_31	1537994.JQFW01000002_gene3396	1.268e-15	92.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,465NU@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
CMS3_k127_2096169_6	448385.sce8548	9.373e-142	467.0	COG0488@1|root,COG0488@2|Bacteria,1QUVR@1224|Proteobacteria,42P66@68525|delta/epsilon subdivisions,2WJ2D@28221|Deltaproteobacteria,2YWET@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_2096169_7	1121935.AQXX01000064_gene3298	4.013e-109	372.0	COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,1RRAQ@1236|Gammaproteobacteria,1XKF1@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_2096169_14	1333998.M2A_2369	9.638e-79	273.0	COG0500@1|root,COG2226@2|Bacteria,1R6F0@1224|Proteobacteria,2VEM7@28211|Alphaproteobacteria,4BS2W@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2096169_15	264198.Reut_A3234	4.611e-69	241.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,2VJ4V@28216|Betaproteobacteria,1K4XV@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_2096169_29	1254432.SCE1572_01960	3.454e-19	98.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,42VN1@68525|delta/epsilon subdivisions,2WRVD@28221|Deltaproteobacteria,2YVPX@29|Myxococcales	28221|Deltaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_2096169_23	497321.C664_04966	6.197e-45	178.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,2KVQF@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS3_k127_2096169_2	215803.DB30_6948	9.13e-211	707.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_2096169_21	1242864.D187_001668	1.567e-47	197.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Thioredoxin_4,VKOR
CMS3_k127_2096169_3	1120956.JHZK01000026_gene799	1.219e-183	597.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2TU6Y@28211|Alphaproteobacteria,1JN51@119043|Rhodobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2096169_11	1242864.D187_010202	1.349e-84	294.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,42QN8@68525|delta/epsilon subdivisions,2WM0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CMS3_k127_2096169_18	1142394.PSMK_17070	8.325e-56	217.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,IU_nuc_hydro
CMS3_k127_2096169_17	1189619.pgond44_07305	1.891e-59	230.0	COG4857@1|root,COG4857@2|Bacteria,4NHKI@976|Bacteroidetes,1I08V@117743|Flavobacteriia,4C2V6@83612|Psychroflexus	976|Bacteroidetes	G	Phosphotransferase enzyme family	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS3_k127_2096169_33	519989.ECTPHS_03607	4.53e-14	81.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,1WXEC@135613|Chromatiales	135613|Chromatiales	S	subfamily IA, variant 1	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
CMS3_k127_2096169_22	391625.PPSIR1_19754	1.831e-45	168.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,431ED@68525|delta/epsilon subdivisions,2WWZ0@28221|Deltaproteobacteria,2YVD5@29|Myxococcales	28221|Deltaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS3_k127_2096169_1	487521.OCU_51100	1.797e-224	713.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,2353H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_2096169_28	1463820.JOGW01000004_gene4524	2.544e-25	121.0	COG0454@1|root,COG0456@2|Bacteria,2IEJU@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2096169_20	586416.GZ22_08020	7.688e-48	178.0	COG0406@1|root,COG0406@2|Bacteria,1V7F8@1239|Firmicutes,4HIR1@91061|Bacilli	91061|Bacilli	G	Phosphoglycerate mutase	gpmA1	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS3_k127_2096169_13	1267535.KB906767_gene4838	6.672e-81	291.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_2096169_4	62928.azo2594	7.46e-158	519.0	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2VIF0@28216|Betaproteobacteria,2KXPU@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_2096169_5	748247.AZKH_4256	6.975e-148	482.0	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2VIIC@28216|Betaproteobacteria,2KY5V@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2101528_13	1266925.JHVX01000001_gene2802	2.674e-60	220.0	COG0463@1|root,COG0463@2|Bacteria,1N840@1224|Proteobacteria,2VQY8@28216|Betaproteobacteria,372E0@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2101528_15	1267535.KB906767_gene4838	6.594e-48	190.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_2101528_22	450851.PHZ_c2242	1.026e-28	135.0	COG0463@1|root,COG0463@2|Bacteria,1MV7X@1224|Proteobacteria,2TYQ8@28211|Alphaproteobacteria,2KIIC@204458|Caulobacterales	204458|Caulobacterales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2101528_18	378806.STAUR_5887	6.274e-40	172.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
CMS3_k127_2101528_10	1282876.BAOK01000001_gene2114	1.343e-80	275.0	COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,2TU91@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS3_k127_2101528_33	926550.CLDAP_15760	7.106e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2G8QS@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2101528_12	886293.Sinac_3913	3.156e-61	229.0	COG0500@1|root,COG2226@2|Bacteria,2J12F@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2101528_1	575540.Isop_3122	2.394e-151	489.0	COG0463@1|root,COG0463@2|Bacteria,2J2HF@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2101528_25	1499967.BAYZ01000076_gene842	2.346e-16	94.0	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
CMS3_k127_2101528_29	1442599.JAAN01000045_gene2779	1.073e-11	80.0	COG0457@1|root,COG0457@2|Bacteria,1R8UZ@1224|Proteobacteria,1RQ7E@1236|Gammaproteobacteria,1X4WX@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_2101528_21	1121403.AUCV01000032_gene2903	1.992e-34	153.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MJAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
CMS3_k127_2101528_19	204669.Acid345_2555	4.125e-39	165.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_2555|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2101528_17	1267535.KB906767_gene5001	1.438e-45	184.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_2101528_7	479434.Sthe_1990	3.655e-106	356.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_2101528_9	234267.Acid_3974	3.775e-86	298.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria	57723|Acidobacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
CMS3_k127_2101528_16	573370.DMR_39210	2.02e-46	194.0	COG0457@1|root,COG0457@2|Bacteria,1RIYN@1224|Proteobacteria,42T31@68525|delta/epsilon subdivisions,2WPYY@28221|Deltaproteobacteria,2M990@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
CMS3_k127_2101528_2	573370.DMR_39200	6.886e-150	487.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WJ85@28221|Deltaproteobacteria,2M8UI@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM membrane bound O-acyl transferase MBOAT	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
CMS3_k127_2101528_26	105422.BBPM01000015_gene1930	6.992e-16	92.0	2EEXH@1|root,338QV@2|Bacteria,2ICQN@201174|Actinobacteria,2NKJZ@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
CMS3_k127_2101528_8	525897.Dbac_3352	8.219e-103	368.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2M8AC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS3_k127_2101528_31	1003195.SCAT_4327	2.826e-09	63.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CMS3_k127_2101528_0	326427.Cagg_1458	1.02e-166	542.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,375CN@32061|Chloroflexia	32061|Chloroflexia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_2101528_3	742821.HMPREF9464_00276	2.381e-144	477.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,4PQR8@995019|Sutterellaceae	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS3_k127_2101528_6	1267533.KB906736_gene1228	1.392e-120	397.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria,2JHZX@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS3_k127_2101528_28	1328313.DS2_05910	1.379e-12	81.0	COG0745@1|root,COG0745@2|Bacteria,1R4NM@1224|Proteobacteria,1S2ZG@1236|Gammaproteobacteria,46CMB@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2101528_30	1128421.JAGA01000002_gene21	2.038e-10	74.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_2101528_5	1307759.JOMJ01000004_gene2863	1.24e-124	408.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2M80I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_2101528_20	1158182.KB905020_gene1845	1.244e-35	153.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,1T11M@1236|Gammaproteobacteria,1X1AJ@135613|Chromatiales	135613|Chromatiales	S	Hemimethylated DNA-binding protein YccV like	-	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
CMS3_k127_2101528_27	1121448.DGI_2478	1.281e-15	89.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_2101528_4	1123023.JIAI01000002_gene4683	5.678e-135	441.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4E1C7@85010|Pseudonocardiales	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS3_k127_2101528_14	1267535.KB906767_gene5001	7.124e-56	220.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_2101528_23	1144275.COCOR_07072	2.581e-28	135.0	2AQ29@1|root,31F7C@2|Bacteria,1NHC1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2101528_11	1169154.KB897778_gene3045	5.724e-66	245.0	COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
CMS3_k127_2101528_24	502025.Hoch_2507	1.04e-20	107.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_2101748_1	530564.Psta_2270	1.671e-26	119.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,2IYGU@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CMS3_k127_2101748_0	530564.Psta_2269	1.514e-111	399.0	COG1074@1|root,COG1074@2|Bacteria,2IX1B@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the helicase family. UvrD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_2124492_9	159087.Daro_2938	7.418e-69	254.0	28MTI@1|root,2ZB1Q@2|Bacteria,1R894@1224|Proteobacteria,2VMZB@28216|Betaproteobacteria,2KVD1@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2124492_10	85643.Tmz1t_2185	2.529e-68	263.0	29FX8@1|root,302UX@2|Bacteria,1P7W7@1224|Proteobacteria,2VM6V@28216|Betaproteobacteria,2KYBY@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2124492_0	748247.AZKH_4252	9.866e-274	883.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,2VJWF@28216|Betaproteobacteria,2KY3E@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2124492_7	1121939.L861_01925	9.51e-81	280.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,1XJNN@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
CMS3_k127_2124492_6	96561.Dole_3102	6.419e-100	339.0	COG1960@1|root,COG1960@2|Bacteria,1NCCF@1224|Proteobacteria,42YB2@68525|delta/epsilon subdivisions,2WUMQ@28221|Deltaproteobacteria,2MMJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
CMS3_k127_2124492_5	392499.Swit_1752	1.056e-101	343.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2K093@204457|Sphingomonadales	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2124492_13	1123023.JIAI01000011_gene8799	1.971e-20	100.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4EAYG@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
CMS3_k127_2124492_8	1123279.ATUS01000001_gene1297	7.889e-80	293.0	COG3386@1|root,COG3386@2|Bacteria,1RFKJ@1224|Proteobacteria,1S4X1@1236|Gammaproteobacteria,1J68P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS3_k127_2124492_11	710685.MycrhN_5758	1.034e-66	240.0	COG0510@1|root,COG0510@2|Bacteria,2I4HR@201174|Actinobacteria,23F84@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_2124492_12	631362.Thi970DRAFT_01235	3.796e-47	192.0	COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1WY4J@135613|Chromatiales	135613|Chromatiales	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CMS3_k127_2124492_3	1415778.JQMM01000001_gene624	1.622e-137	449.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1J4ST@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0306 Phosphate sulphate permeases	pitA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS3_k127_2124492_4	1121937.AUHJ01000001_gene811	4.369e-121	404.0	COG5361@1|root,COG5361@2|Bacteria,1PF7H@1224|Proteobacteria,1RY0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
CMS3_k127_2124492_1	1304275.C41B8_05778	1.008e-209	672.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,1RQK5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
CMS3_k127_2124492_14	1117647.M5M_19300	3.676e-09	70.0	2EAIM@1|root,334MN@2|Bacteria,1N6XM@1224|Proteobacteria,1SF6C@1236|Gammaproteobacteria,1J73Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2124492_2	1282876.BAOK01000001_gene1966	1.222e-182	584.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2U1B0@28211|Alphaproteobacteria,4BPJI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	CP	Proton-conducting membrane transporter	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS3_k127_212740_2	1521187.JPIM01000014_gene1776	6.431e-07	60.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_16
CMS3_k127_212740_3	1396418.BATQ01000023_gene5183	3.131e-05	54.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,DUF285,Flg_new,LRR_5,PKD
CMS3_k127_212740_0	1282876.BAOK01000001_gene2836	2.127e-115	381.0	COG4943@1|root,COG4943@2|Bacteria,1QZSA@1224|Proteobacteria,2TYDN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS3_k127_2162051_0	404589.Anae109_1778	0.0	1058.0	COG1215@1|root,COG3405@1|root,COG1215@2|Bacteria,COG3405@2|Bacteria,1MWF8@1224|Proteobacteria,42TR0@68525|delta/epsilon subdivisions,2WQ94@28221|Deltaproteobacteria,2Z383@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl hydrolases family 8	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_hydro_8,Glyco_trans_2_3,Glycos_transf_2,PilZ
CMS3_k127_2162051_3	404589.Anae109_1777	1.505e-108	384.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_1777|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2162051_11	1168059.KB899087_gene1061	2.976e-06	59.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS3_k127_2162051_7	1522072.IL54_2358	5.055e-63	233.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2U38P@28211|Alphaproteobacteria,2K37I@204457|Sphingomonadales	204457|Sphingomonadales	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
CMS3_k127_2162051_6	215803.DB30_6266	6.062e-72	259.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2X5YA@28221|Deltaproteobacteria,2YUMQ@29|Myxococcales	28221|Deltaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS3_k127_2162051_9	1038862.KB893842_gene355	1.32e-29	132.0	COG2207@1|root,COG2207@2|Bacteria,1QUXX@1224|Proteobacteria,2VF4V@28211|Alphaproteobacteria,3JYAV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
CMS3_k127_2162051_10	1463934.JOCF01000007_gene1369	6.7e-26	121.0	COG2957@1|root,COG2957@2|Bacteria,2H912@201174|Actinobacteria	201174|Actinobacteria	E	Porphyromonas-type peptidyl-arginine deiminase	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CMS3_k127_2162051_5	756272.Plabr_0265	2.603e-102	349.0	COG2211@1|root,COG2211@2|Bacteria,2IY9C@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2162051_2	1267005.KB911255_gene2872	4.024e-238	754.0	COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,1N4F5@1224|Proteobacteria,2U4DQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_2162051_4	1444309.JAQG01000012_gene2066	3.556e-108	397.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,26RV3@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_2162051_8	96561.Dole_0549	1.27e-38	150.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MKH2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_2162051_1	909663.KI867150_gene2735	1.789e-240	759.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_216580_9	1499967.BAYZ01000139_gene142	8.88e-39	153.0	COG1216@1|root,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_216580_14	765912.Thimo_3078	1.513e-11	78.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria,1WX9D@135613|Chromatiales	135613|Chromatiales	C	eight transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS3_k127_216580_1	1034943.BN1094_00501	7.689e-125	414.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1JEEN@118969|Legionellales	118969|Legionellales	GM	ABC transporter	wzt	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_216580_4	266779.Meso_3693	1.832e-73	256.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2U57D@28211|Alphaproteobacteria,43JWS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	GM	ABC-2 type transporter	wzm	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_216580_10	1521187.JPIM01000041_gene544	1.002e-34	151.0	COG0438@1|root,COG0438@2|Bacteria,2G7Z3@200795|Chloroflexi,376IC@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_216580_0	195250.CM001776_gene1279	4.281e-176	599.0	COG0438@1|root,COG1196@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1196@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1G0TI@1117|Cyanobacteria,1GYRA@1129|Synechococcus	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
CMS3_k127_216580_3	1453501.JELR01000002_gene231	5.705e-92	328.0	COG1216@1|root,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,1RQFV@1236|Gammaproteobacteria,466Q7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_216580_2	1453501.JELR01000002_gene230	1.73e-115	411.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,1S0BA@1236|Gammaproteobacteria,464QN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	2.4.1.56	ko:K03280	ko00540,ko01100,map00540,map01100	M00080	R01996	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4,GT9	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_216580_6	1278073.MYSTI_02474	1.582e-59	220.0	COG0500@1|root,COG2226@2|Bacteria,1MZ58@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_216580_12	622637.KE124774_gene2658	1.004e-31	136.0	2DZ18@1|root,34C3C@2|Bacteria,1P1EQ@1224|Proteobacteria,2UV4R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_216580_11	203124.Tery_1676	1.41e-33	146.0	28KEP@1|root,2ZA0W@2|Bacteria,1G2EV@1117|Cyanobacteria,1H8V1@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_216580_7	266117.Rxyl_3109	1.698e-58	234.0	COG1216@1|root,COG1216@2|Bacteria,2HTM1@201174|Actinobacteria,4CPU8@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_216580_5	1167006.UWK_01998	1.577e-71	276.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,42QJ7@68525|delta/epsilon subdivisions,2WPQE@28221|Deltaproteobacteria,2MKG7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_216580_8	1123377.AUIV01000003_gene1843	1.022e-42	181.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1X3GZ@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
CMS3_k127_216580_13	693986.MOC_4158	2.027e-29	137.0	COG0438@1|root,COG3754@1|root,COG0438@2|Bacteria,COG3754@2|Bacteria,1RF3D@1224|Proteobacteria,2TUNA@28211|Alphaproteobacteria,1JRD7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,RgpF
CMS3_k127_2166874_7	211165.AJLN01000114_gene5953	2.179e-23	110.0	COG0500@1|root,COG2226@2|Bacteria,1G4JN@1117|Cyanobacteria,1JJFD@1189|Stigonemataceae	1117|Cyanobacteria	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_2166874_5	925775.XVE_1985	3.679e-67	234.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,1RXAQ@1236|Gammaproteobacteria,1X73Q@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	wxcM	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep
CMS3_k127_2166874_3	1313172.YM304_41520	3.396e-97	330.0	COG5285@1|root,COG5285@2|Bacteria,2GNXP@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_2166874_6	1121904.ARBP01000003_gene6447	6.327e-37	145.0	COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,47VIF@768503|Cytophagia	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
CMS3_k127_2166874_2	1229780.BN381_40090	2.057e-112	374.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2166874_4	690850.Desaf_1110	1.507e-77	266.0	COG0467@1|root,COG0467@2|Bacteria,1RFBT@1224|Proteobacteria,42QWP@68525|delta/epsilon subdivisions,2WMB2@28221|Deltaproteobacteria,2M9K6@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2166874_1	1120966.AUBU01000003_gene1423	4.313e-121	405.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Sodium alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS3_k127_2166874_0	196367.JNFG01000008_gene6519	9.937e-148	482.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VHST@28216|Betaproteobacteria,1JZV1@119060|Burkholderiaceae	1224|Proteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS3_k127_2167805_0	1205680.CAKO01000002_gene2489	1.705e-122	407.0	COG2159@1|root,COG2159@2|Bacteria,1P6G6@1224|Proteobacteria,2TU10@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_2168607_8	392499.Swit_4250	5.213e-14	76.0	COG0625@1|root,COG0625@2|Bacteria,1NA1U@1224|Proteobacteria,2UJ3J@28211|Alphaproteobacteria,2KD18@204457|Sphingomonadales	204457|Sphingomonadales	O	PFAM Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
CMS3_k127_2168607_3	876044.IMCC3088_1936	7.035e-91	312.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,1RP7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2168607_0	517722.AEUE01000001_gene2696	2.384e-222	710.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2TS28@28211|Alphaproteobacteria,2JZVY@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
CMS3_k127_2168607_1	631454.N177_3776	5.367e-158	506.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,1JN0C@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	Male sterility protein	rfbB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_2168607_9	1089553.Tph_c01990	6.748e-07	61.0	2DP62@1|root,330P7@2|Bacteria,1VJ9U@1239|Firmicutes,25DF9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2168607_4	326424.FRAAL6221	2.395e-80	299.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria,4EUU2@85013|Frankiales	201174|Actinobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
CMS3_k127_2168607_6	251221.35213174	3.276e-59	216.0	COG1216@1|root,COG1216@2|Bacteria,1G6GW@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2168607_2	471852.Tcur_2583	2.248e-128	433.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_2168607_5	756272.Plabr_3176	3.928e-60	222.0	COG0628@1|root,COG0628@2|Bacteria,2J05D@203682|Planctomycetes	203682|Planctomycetes	S	AI-2E family transporter	-	-	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
CMS3_k127_2168607_7	1415780.JPOG01000001_gene2509	1.565e-24	117.0	COG0760@1|root,COG0760@2|Bacteria,1NNJD@1224|Proteobacteria,1SVGM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
CMS3_k127_2168607_10	1415780.JPOG01000001_gene2510	2.571e-06	61.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1X5V2@135614|Xanthomonadales	135614|Xanthomonadales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS3_k127_2173161_1	1242864.D187_005198	2.402e-70	250.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions	1224|Proteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_2173161_2	557599.MKAN_02205	9.409e-68	241.0	COG5285@1|root,COG5285@2|Bacteria,2HSYC@201174|Actinobacteria,23EJ4@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_2173161_4	1038859.AXAU01000001_gene3169	9.401e-30	139.0	COG2227@1|root,COG2227@2|Bacteria,1RHSX@1224|Proteobacteria,2TWSI@28211|Alphaproteobacteria,3JXUH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_2173161_3	1121403.AUCV01000001_gene771	1.37e-54	202.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB_2	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS3_k127_2173161_0	880073.Calab_0376	3.035e-96	333.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2NNX4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS3_k127_2173370_3	335543.Sfum_2531	2.422e-80	279.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2MRAV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS3_k127_2173370_6	1123519.PSJM300_09140	2.497e-05	57.0	COG0745@1|root,COG0745@2|Bacteria,1RA6Z@1224|Proteobacteria,1SYDG@1236|Gammaproteobacteria,1Z1MS@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	qseB	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2173370_5	749927.AMED_8982	8.685e-24	106.0	COG0346@1|root,COG0346@2|Bacteria,2H5Y5@201174|Actinobacteria,4EBMJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2173370_4	1206730.BAGA01000072_gene2014	1.031e-35	156.0	COG1960@1|root,COG1960@2|Bacteria,2HFPQ@201174|Actinobacteria,4G6WP@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_2173370_0	452662.SJA_C2-04050	3.473e-144	488.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TUFX@28211|Alphaproteobacteria,2K8FT@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2173370_2	222534.KB893712_gene4913	3.01e-119	398.0	COG1960@1|root,COG1960@2|Bacteria,2GNVM@201174|Actinobacteria,4EUAX@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2173370_1	1056816.JAFQ01000004_gene5069	2.335e-126	433.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria,4FXMK@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_219804_25	29581.BW37_03320	9.86e-29	134.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH,Rieske
CMS3_k127_219804_8	1469613.JT55_16075	4.452e-88	298.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2TW7Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
CMS3_k127_219804_12	1173026.Glo7428_3726	2.307e-77	269.0	COG2327@1|root,COG2327@2|Bacteria,1G3R3@1117|Cyanobacteria	1117|Cyanobacteria	S	SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
CMS3_k127_219804_29	1502851.FG93_05476	4.926e-10	73.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,2UK9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_219804_9	1198232.CYCME_1447	9.429e-84	304.0	COG1216@1|root,COG1216@2|Bacteria,1RHVX@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_219804_23	1198232.CYCME_1449	4.833e-53	196.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria,4635B@72273|Thiotrichales	72273|Thiotrichales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_219804_34	1198232.CYCME_1453	0.0001418	55.0	COG1232@1|root,COG1232@2|Bacteria,1QX3T@1224|Proteobacteria,1T3RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_219804_0	886293.Sinac_5556	8.637e-181	587.0	COG1232@1|root,COG1232@2|Bacteria,2IYF5@203682|Planctomycetes	203682|Planctomycetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_219804_31	339860.Msp_0066	6.48e-07	62.0	COG2244@1|root,arCOG02209@2157|Archaea	2157|Archaea	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_219804_10	926550.CLDAP_36130	1.508e-82	304.0	COG0421@1|root,COG0421@2|Bacteria,2G80S@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_219804_4	886293.Sinac_6944	5.802e-109	366.0	COG2755@1|root,COG2755@2|Bacteria,2IWSK@203682|Planctomycetes	203682|Planctomycetes	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_3
CMS3_k127_219804_11	1123242.JH636435_gene1055	1.378e-77	271.0	COG3618@1|root,COG3618@2|Bacteria,2IY4K@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_219804_1	46234.ANA_C12635	3.318e-164	533.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1HN29@1161|Nostocales	1117|Cyanobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_219804_24	1123401.JHYQ01000010_gene2453	1.345e-35	150.0	2BSEF@1|root,32MGE@2|Bacteria,1N9VN@1224|Proteobacteria,1SG8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_219804_2	1121403.AUCV01000020_gene3105	8.769e-163	528.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,42NE7@68525|delta/epsilon subdivisions,2WJ77@28221|Deltaproteobacteria,2MM3R@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_219804_18	1283300.ATXB01000001_gene399	6.745e-66	233.0	2DKXW@1|root,30TMD@2|Bacteria,1R3IE@1224|Proteobacteria,1SPK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4410)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4410
CMS3_k127_219804_5	1219035.NT2_05_02510	1.547e-108	371.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,2V983@28211|Alphaproteobacteria,2K2B5@204457|Sphingomonadales	204457|Sphingomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C,GMC_oxred_N
CMS3_k127_219804_33	1499967.BAYZ01000090_gene4941	5.693e-05	56.0	2DDA6@1|root,2ZH98@2|Bacteria	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT
CMS3_k127_219804_7	1121403.AUCV01000020_gene3107	8.847e-98	329.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,43DE0@68525|delta/epsilon subdivisions,2X8JX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_219804_13	1469613.JT55_16070	2.919e-75	274.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_219804_19	420247.Msm_0385	4.614e-65	245.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,23PFJ@183925|Methanobacteria	183925|Methanobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_219804_17	386456.JQKN01000002_gene2815	3.912e-69	254.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,23PFJ@183925|Methanobacteria	183925|Methanobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_219804_3	489825.LYNGBM3L_64070	2.277e-124	421.0	COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria,1H8D4@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_219804_15	1042326.AZNV01000009_gene2809	1.251e-71	252.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,2U6HF@28211|Alphaproteobacteria,4BAG1@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
CMS3_k127_219804_30	1229485.AMYV01000004_gene2312	3.371e-08	66.0	COG2244@1|root,COG2244@2|Bacteria,1R9XE@1224|Proteobacteria,1S2YR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	rfbX	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944	-	ko:K03328,ko:K18799	-	-	-	-	ko00000,ko01005,ko02000	2.A.66.2,2.A.66.2.1	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_219804_14	1116232.AHBF01000013_gene3068	3.159e-75	264.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_219804_22	1121937.AUHJ01000005_gene2148	2.223e-57	221.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,1SWMP@1236|Gammaproteobacteria,46975@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_219804_16	591158.SSMG_04683	3.716e-70	250.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS3_k127_219804_6	1280948.HY36_12360	2.897e-104	349.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,2TSUK@28211|Alphaproteobacteria,43ZY1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
CMS3_k127_219804_20	435908.IDSA_05165	3.642e-60	218.0	2BHRH@1|root,32BUY@2|Bacteria,1MZ2C@1224|Proteobacteria,1SARJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_219804_28	69014.TK0839	1.002e-16	94.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,242IJ@183968|Thermococci	183968|Thermococci	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_219804_26	477974.Daud_0678	2.732e-27	128.0	COG0778@1|root,COG0778@2|Bacteria,1UY72@1239|Firmicutes,248YJ@186801|Clostridia,266KR@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_219804_32	67275.JOAP01000004_gene6634	2.779e-06	59.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_219804_27	344747.PM8797T_22858	7.824e-20	95.0	COG0607@1|root,COG0607@2|Bacteria,2J1JN@203682|Planctomycetes	203682|Planctomycetes	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_219804_21	1161401.ASJA01000013_gene692	3.592e-58	205.0	COG1793@1|root,COG1793@2|Bacteria,1NTIR@1224|Proteobacteria,2UPWW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
CMS3_k127_2217697_9	251221.35214207	4.716e-18	99.0	COG0702@1|root,COG0702@2|Bacteria,1GHPI@1117|Cyanobacteria	1117|Cyanobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
CMS3_k127_2217697_10	215803.DB30_5528	5.112e-11	76.0	COG0738@1|root,COG0738@2|Bacteria,1R8F9@1224|Proteobacteria,42WYS@68525|delta/epsilon subdivisions,2WSP2@28221|Deltaproteobacteria,2YU61@29|Myxococcales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2217697_7	1191523.MROS_0340	1.071e-35	147.0	COG2151@1|root,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	paaD	-	-	ko:K02612,ko:K03593	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko03029,ko03036	-	-	-	FeS_assembly_P
CMS3_k127_2217697_6	1183438.GKIL_1934	2.061e-50	188.0	COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria	1117|Cyanobacteria	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS3_k127_2217697_1	215803.DB30_6995	1.463e-154	519.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS3_k127_2217697_5	279714.FuraDRAFT_0568	5.355e-82	295.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2VMJ9@28216|Betaproteobacteria	28216|Betaproteobacteria	O	assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS3_k127_2217697_3	1382359.JIAL01000001_gene679	2.393e-110	362.0	COG0396@1|root,COG0396@2|Bacteria,3Y3S4@57723|Acidobacteria	57723|Acidobacteria	O	ABC transporter	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS3_k127_2217697_0	234267.Acid_7699	3.042e-246	767.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS3_k127_2217697_8	243233.MCA0993	2.879e-29	126.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1XF99@135618|Methylococcales	135618|Methylococcales	K	TIGRFAM SUF system FeS cluster assembly, Rtf2-type regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_2217697_2	1283283.ATXA01000022_gene283	8.275e-120	399.0	COG2159@1|root,COG2159@2|Bacteria,2H94T@201174|Actinobacteria,4EWGY@85013|Frankiales	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2217697_4	247634.GPB2148_3742	1.181e-86	323.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2257035_6	1246995.AFR_25055	2.194e-103	349.0	COG3570@1|root,COG3570@2|Bacteria,2GZSC@201174|Actinobacteria,4DC6T@85008|Micromonosporales	201174|Actinobacteria	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
CMS3_k127_2257035_5	570952.ATVH01000020_gene1030	2.972e-115	385.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2U1C5@28211|Alphaproteobacteria,2JZA8@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
CMS3_k127_2257035_16	1449049.JONW01000002_gene2543	2.574e-28	125.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,2UCEY@28211|Alphaproteobacteria,2KJ4F@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_2257035_11	1254432.SCE1572_05130	2.936e-54	195.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,42QW0@68525|delta/epsilon subdivisions,2WMZW@28221|Deltaproteobacteria,2Z0RG@29|Myxococcales	28221|Deltaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
CMS3_k127_2257035_12	1110502.TMO_0733	5.192e-51	198.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2U87P@28211|Alphaproteobacteria,2JTMV@204441|Rhodospirillales	204441|Rhodospirillales	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2257035_10	1242864.D187_000772	6.176e-89	307.0	COG0625@1|root,COG0625@2|Bacteria,1NE6Z@1224|Proteobacteria,433UT@68525|delta/epsilon subdivisions,2X3JN@28221|Deltaproteobacteria,2YWCC@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3,GST_N
CMS3_k127_2257035_13	1380387.JADM01000007_gene818	6.794e-48	174.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1SDPW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_2257035_4	1124780.ANNU01000063_gene608	5.034e-124	412.0	COG1409@1|root,COG2133@1|root,COG3291@1|root,COG3488@1|root,COG4932@1|root,COG1409@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3488@2|Bacteria,COG4932@2|Bacteria,4NG9B@976|Bacteroidetes,47U64@768503|Cytophagia	976|Bacteroidetes	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,PKD
CMS3_k127_2257035_2	243233.MCA1130	5.178e-166	537.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XDUY@135618|Methylococcales	135618|Methylococcales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CMS3_k127_2257035_18	316067.Geob_3648	5.33e-13	82.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria	2|Bacteria	M	Sugar transferase	epsL	-	-	ko:K19428	-	-	-	-	ko00000,ko01000	-	-	-	Bac_transf
CMS3_k127_2257035_1	316067.Geob_3650	1.516e-193	625.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_2257035_15	247639.MGP2080_02166	3.707e-37	149.0	COG1309@1|root,COG1309@2|Bacteria,1N6FM@1224|Proteobacteria,1SZ1U@1236|Gammaproteobacteria,1J7BT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2257035_8	1280950.HJO_11232	3.727e-98	331.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,43YGD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	GM	NAD-dependent epimerase dehydratase family protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_2257035_9	247634.GPB2148_2309	1.572e-90	321.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RNEZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2257035_7	292415.Tbd_1583	1.406e-102	340.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria,1KSMU@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2257035_0	991905.SL003B_1030	8.04e-276	886.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_2257035_3	991905.SL003B_1031	3.518e-127	418.0	COG0845@1|root,COG0845@2|Bacteria,1Q112@1224|Proteobacteria,2V906@28211|Alphaproteobacteria,4BSRF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
CMS3_k127_2257035_14	864051.BurJ1DRAFT_3700	2.588e-43	181.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
CMS3_k127_2257035_17	378806.STAUR_7829	4.659e-20	98.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2272244_1	398579.Spea_3284	7.056e-170	553.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,2QAGX@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
CMS3_k127_2272244_21	1123355.JHYO01000024_gene1815	3.404e-42	166.0	COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,2UA1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG1006 Multisubunit Na H antiporter, MnhC subunit	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
CMS3_k127_2272244_22	2340.JV46_13170	6.35e-42	169.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria,1J5HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG2111 Multisubunit Na H antiporter, MnhB subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040,MnhB
CMS3_k127_2272244_24	1238182.C882_4241	1.029e-35	149.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,2U7UT@28211|Alphaproteobacteria,2JT0K@204441|Rhodospirillales	204441|Rhodospirillales	P	Domain of unknown function (DUF4040)	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040
CMS3_k127_2272244_33	1333998.M2A_0553	5.244e-18	93.0	COG1320@1|root,COG1320@2|Bacteria,1N75I@1224|Proteobacteria,2UETR@28211|Alphaproteobacteria,4BQTT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Na+/H+ antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
CMS3_k127_2272244_31	1247963.JPHU01000005_gene352	6.107e-23	109.0	COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria,2UHB7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
CMS3_k127_2272244_26	1265313.HRUBRA_01923	5.077e-34	138.0	COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,1S7Z3@1236|Gammaproteobacteria,1J63V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Na+/H+ ion antiporter subunit	mnhE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
CMS3_k127_2272244_38	1380350.JIAP01000016_gene3800	4.673e-08	64.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
CMS3_k127_2272244_9	1131269.AQVV01000013_gene1720	2.858e-94	321.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2272244_35	394221.Mmar10_1416	1.972e-14	86.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,2UEU1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_2272244_6	1122970.AUHC01000011_gene2680	2.049e-127	421.0	COG4638@1|root,COG4638@2|Bacteria,1R83A@1224|Proteobacteria,2U4UP@28211|Alphaproteobacteria,2K36D@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_2272244_15	1206731.BAGB01000035_gene9156	3.341e-67	250.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria,4G7N3@85025|Nocardiaceae	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
CMS3_k127_2272244_17	402626.Rpic_1260	5.594e-62	226.0	COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2VNWW@28216|Betaproteobacteria,1KHHM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS3_k127_2272244_14	402881.Plav_0926	3.184e-68	244.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_2272244_8	2055.JNXA01000001_gene1729	5.478e-98	331.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4GBMN@85026|Gordoniaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2272244_12	684949.ATTJ01000003_gene3147	3.968e-78	287.0	COG0654@1|root,COG0654@2|Bacteria,1WMU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_2272244_7	497965.Cyan7822_0595	5.628e-107	373.0	COG2133@1|root,COG2931@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,1GHTZ@1117|Cyanobacteria,3KJHD@43988|Cyanothece	1117|Cyanobacteria	Q	hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS3_k127_2272244_18	760568.Desku_3526	1.014e-58	224.0	COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,24C1C@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2272244_37	13035.Dacsa_0359	1.496e-09	71.0	COG0038@1|root,COG0517@1|root,COG0589@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG0589@2|Bacteria,1G17J@1117|Cyanobacteria	1117|Cyanobacteria	PT	Chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Usp,Voltage_CLC
CMS3_k127_2272244_36	517722.AEUE01000004_gene964	2.272e-14	87.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,2UCF1@28211|Alphaproteobacteria,2K7PQ@204457|Sphingomonadales	204457|Sphingomonadales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS3_k127_2272244_11	1122201.AUAZ01000001_gene2304	8.72e-81	299.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,4661V@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
CMS3_k127_2272244_3	1278073.MYSTI_01297	3.512e-162	526.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS3_k127_2272244_25	1403819.BATR01000054_gene1681	2.114e-34	140.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2,Cupin_3
CMS3_k127_2272244_41	1128421.JAGA01000002_gene1599	0.0002725	54.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2272244_4	118163.Ple7327_4336	1.079e-141	470.0	COG2303@1|root,COG2303@2|Bacteria,1GB9F@1117|Cyanobacteria	1117|Cyanobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,NAD_binding_8
CMS3_k127_2272244_5	118163.Ple7327_4337	1.142e-128	430.0	COG0399@1|root,COG0399@2|Bacteria,1GF8X@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM DegT DnrJ EryC1 StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_2272244_13	402881.Plav_0731	8.029e-73	262.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2272244_40	761193.Runsl_3102	1.336e-07	58.0	2DZQQ@1|root,336S7@2|Bacteria,4NV3W@976|Bacteroidetes,47SKU@768503|Cytophagia	976|Bacteroidetes	S	Transmembrane family 220, helix	-	-	-	-	-	-	-	-	-	-	-	-	TMEM220
CMS3_k127_2272244_27	67356.KL575596_gene6579	7.818e-31	136.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_2272244_20	1238182.C882_1345	6.053e-50	190.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2JRUZ@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CMS3_k127_2272244_29	1313172.YM304_02940	1.212e-23	112.0	COG3173@1|root,COG3173@2|Bacteria,2I630@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_2272244_30	391625.PPSIR1_11135	2.184e-23	102.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CMS3_k127_2272244_23	1038859.AXAU01000004_gene4450	8.236e-42	165.0	COG0346@1|root,COG0346@2|Bacteria,1N2KZ@1224|Proteobacteria,2UBQR@28211|Alphaproteobacteria,3K6CJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2272244_28	1382356.JQMP01000004_gene531	3.944e-25	123.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2272244_19	1267535.KB906767_gene4838	1.507e-58	225.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_2272244_39	223192.XP_007913050.1	1.328e-07	66.0	2CMGW@1|root,2QQB7@2759|Eukaryota,39TQ2@33154|Opisthokonta,3NZ5T@4751|Fungi,3QR06@4890|Ascomycota,215XR@147550|Sordariomycetes	4751|Fungi	S	viral a-type inclusion protein repeat domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2272244_0	1521187.JPIM01000074_gene2856	1.465e-183	592.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,375BH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS3_k127_2272244_2	313603.FB2170_04140	3.238e-168	542.0	COG1858@1|root,COG1858@2|Bacteria,4NJ4X@976|Bacteroidetes,1I05W@117743|Flavobacteriia	976|Bacteroidetes	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2272244_32	471853.Bcav_2700	6.558e-19	88.0	COG1028@1|root,COG1028@2|Bacteria,2GP5U@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2303451_0	66875.JODY01000006_gene2209	1.224e-162	524.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_2303451_2	1121937.AUHJ01000010_gene1736	1.548e-78	266.0	2C04H@1|root,32R6A@2|Bacteria,1QUR6@1224|Proteobacteria,1T3JZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_2303451_5	1120950.KB892757_gene6616	3.064e-54	200.0	COG0637@1|root,COG0637@2|Bacteria,2IQD3@201174|Actinobacteria,4DRPS@85009|Propionibacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS3_k127_2303451_7	324602.Caur_3759	3.813e-36	154.0	COG0438@1|root,COG0438@2|Bacteria,2G7Z3@200795|Chloroflexi,376IC@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2303451_8	479434.Sthe_1762	2.33e-11	77.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2303451_10	1502851.FG93_04476	0.0003627	47.0	COG3618@1|root,COG3618@2|Bacteria,1P5PT@1224|Proteobacteria,2U3BR@28211|Alphaproteobacteria,3JU4M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS3_k127_2303451_3	525904.Tter_0452	5.3e-67	240.0	COG1028@1|root,COG1028@2|Bacteria	525904.Tter_0452|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
CMS3_k127_2303451_4	1007103.AFHW01000081_gene1548	2.558e-55	205.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,4ISNQ@91061|Bacilli,26V82@186822|Paenibacillaceae	91061|Bacilli	KQ	MerR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,TipAS
CMS3_k127_2303451_1	414684.RC1_1355	1.079e-92	332.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2TSMR@28211|Alphaproteobacteria,2JRNA@204441|Rhodospirillales	204441|Rhodospirillales	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_2303451_6	1336243.JAEA01000001_gene1686	1.629e-52	194.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2U5C5@28211|Alphaproteobacteria,1JTVZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_C_3,GST_N_3
CMS3_k127_2311603_12	1001585.MDS_3637	2.178e-29	127.0	COG0517@1|root,COG0517@2|Bacteria,1QTZR@1224|Proteobacteria,1S7SY@1236|Gammaproteobacteria,1YGJE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_2311603_3	391625.PPSIR1_12063	3.796e-164	546.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,42PMT@68525|delta/epsilon subdivisions,2WK84@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_10,NQRA,NQRA_SLBB
CMS3_k127_2311603_4	391625.PPSIR1_12058	8.039e-146	496.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,42MTU@68525|delta/epsilon subdivisions,2WKN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
CMS3_k127_2311603_11	1109445.AGSX01000184_gene2303	1.014e-64	230.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,1Z0CW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
CMS3_k127_2311603_8	1137799.GZ78_26900	1.245e-83	283.0	COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,1XHE7@135619|Oceanospirillales	135619|Oceanospirillales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS3_k127_2311603_7	717774.Marme_2586	3.46e-85	287.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,1XIB2@135619|Oceanospirillales	135619|Oceanospirillales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS3_k127_2311603_0	1122244.AUGF01000018_gene2117	5.034e-195	616.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,3NKFQ@468|Moraxellaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0004497,GO:0005488,GO:0005575,GO:0006725,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016705,GO:0016709,GO:0018662,GO:0018958,GO:0018959,GO:0019336,GO:0019439,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044425,GO:0046191,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902494	1.6.5.8	ko:K00351,ko:K16246	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS3_k127_2311603_10	391625.PPSIR1_12033	2.559e-81	285.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2YV2N@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS3_k127_2311603_14	1280950.HJO_08497	1.979e-21	99.0	COG0251@1|root,COG0251@2|Bacteria,1PHJK@1224|Proteobacteria,2V89Y@28211|Alphaproteobacteria,4405J@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_2311603_5	331869.BAL199_19598	1.021e-140	457.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,4BPRP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Aminotransferase	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_2311603_2	1089552.KI911559_gene3521	2.877e-175	563.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2TR7P@28211|Alphaproteobacteria,2JV8S@204441|Rhodospirillales	204441|Rhodospirillales	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS3_k127_2311603_1	378806.STAUR_2372	7.642e-190	627.0	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,438FH@68525|delta/epsilon subdivisions,2X3QH@28221|Deltaproteobacteria,2YWUI@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_2311603_9	285514.JNWO01000014_gene5649	1.161e-82	307.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2311603_6	1229780.BN381_30019	4.56e-127	421.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_2311603_13	1227457.C451_18358	7.518e-29	125.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2376566_12	123899.JPQP01000020_gene1912	2.575e-20	94.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VJJ6@28216|Betaproteobacteria,3T1K2@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS3_k127_2376566_6	1254432.SCE1572_28315	1.364e-34	145.0	COG1975@1|root,COG2068@1|root,COG1975@2|Bacteria,COG2068@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria,2YWIQ@29|Myxococcales	28221|Deltaproteobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3,XdhC_C,XdhC_CoxI
CMS3_k127_2376566_1	448385.sce4660	1.378e-92	328.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2Z3JZ@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS3_k127_2376566_2	1121946.AUAX01000022_gene3840	3.059e-80	277.0	2DBF0@1|root,2Z8VT@2|Bacteria,2I88D@201174|Actinobacteria,4DIBF@85008|Micromonosporales	201174|Actinobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
CMS3_k127_2376566_8	292459.STH2795	2.749e-25	115.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24TCI@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2376566_14	358396.C445_07725	1.016e-14	88.0	arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,23TMB@183963|Halobacteria	183963|Halobacteria	S	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_2376566_13	237368.SCABRO_03810	8.517e-19	101.0	2EM59@1|root,33EUK@2|Bacteria	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2376566_4	443143.GM18_1345	4.352e-70	248.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS3_k127_2376566_5	1267535.KB906767_gene5354	1.259e-66	236.0	COG0084@1|root,COG0084@2|Bacteria,3Y4DK@57723|Acidobacteria,2JJ1I@204432|Acidobacteriia	204432|Acidobacteriia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS3_k127_2376566_17	518766.Rmar_1575	1.149e-09	70.0	COG0758@1|root,COG0758@2|Bacteria,4P58M@976|Bacteroidetes,1FJHP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
CMS3_k127_2376566_16	768671.ThimaDRAFT_1668	1.005e-12	72.0	COG0758@1|root,COG0758@2|Bacteria,1MZGB@1224|Proteobacteria,1S95S@1236|Gammaproteobacteria,1WYBS@135613|Chromatiales	135613|Chromatiales	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
CMS3_k127_2376566_0	56780.SYN_00558	3.059e-182	586.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MQAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS3_k127_2376566_9	1267535.KB906767_gene5403	1.186e-23	117.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene5403|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2376566_3	710686.Mycsm_02647	1.984e-76	266.0	COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria,235V2@1762|Mycobacteriaceae	201174|Actinobacteria	G	Class II aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS3_k127_2376566_7	672.VV93_v1c28280	1.455e-31	142.0	2BN55@1|root,32GS7@2|Bacteria,1R7WY@1224|Proteobacteria,1RQ71@1236|Gammaproteobacteria,1XU9A@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2376566_11	429009.Adeg_2119	2.181e-20	103.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,25E6M@186801|Clostridia,42J77@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS3_k127_2376566_10	404589.Anae109_4500	4.442e-23	110.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2YVIX@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_2376566_15	1034345.CAEM01000014_gene155	2.827e-13	76.0	COG0694@1|root,COG0694@2|Bacteria,2H0W2@201174|Actinobacteria,4CWA6@84998|Coriobacteriia	84998|Coriobacteriia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
CMS3_k127_2376566_18	483219.LILAB_20495	4.025e-09	60.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1RGUX@1224|Proteobacteria,437BZ@68525|delta/epsilon subdivisions,2WQNB@28221|Deltaproteobacteria,2YVJC@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS3_k127_2383734_6	383372.Rcas_2471	1.326e-41	168.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2383734_8	1101190.ARWB01000001_gene1273	6.359e-35	154.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2TU5Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
CMS3_k127_2383734_5	1267535.KB906767_gene4838	5.322e-44	185.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_2383734_9	864069.MicloDRAFT_00027830	7.852e-33	146.0	COG0494@1|root,COG0494@2|Bacteria,1RM2Y@1224|Proteobacteria,2UAF2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_2383734_1	83406.HDN1F_10660	3.11e-127	424.0	COG1680@1|root,COG1680@2|Bacteria,1R5MK@1224|Proteobacteria,1S015@1236|Gammaproteobacteria,1JBWQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_2383734_0	247634.GPB2148_671	1.905e-197	629.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,1RPXH@1236|Gammaproteobacteria,1J4F5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Succinate dehydrogenase fumarate reductase flavoprotein subunit	-	-	1.3.99.33	ko:K17363	ko00340,map00340	-	R10330	RC00669	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,FMN_bind
CMS3_k127_2383734_7	439235.Dalk_2007	1.391e-38	167.0	COG2755@1|root,COG2755@2|Bacteria,1NJHS@1224|Proteobacteria,42Y0B@68525|delta/epsilon subdivisions,2WTGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2383734_2	67373.JOBF01000012_gene3992	1.939e-126	413.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2383734_3	94624.Bpet0765	4.574e-124	414.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2VJ3D@28216|Betaproteobacteria,3T3B1@506|Alcaligenaceae	28216|Betaproteobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS3_k127_2383734_4	426716.JOAJ01000002_gene1970	1.691e-93	325.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4FW1X@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2386669_0	1205680.CAKO01000008_gene4121	1.011e-123	403.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TVNW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_2386669_4	1496688.ER33_12195	2.906e-22	108.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1G0CZ@1117|Cyanobacteria,22TAG@167375|Cyanobium	1117|Cyanobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS3_k127_2386669_1	136273.GY22_16800	6.171e-67	247.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,1W7ZT@1268|Micrococcaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_2386669_2	1121033.AUCF01000006_gene4093	8.028e-40	154.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,2JT8X@204441|Rhodospirillales	204441|Rhodospirillales	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_2386669_3	398525.KB900701_gene6754	1.056e-39	159.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2U99K@28211|Alphaproteobacteria,3JYHS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_2386669_5	1384056.N787_03790	1.208e-14	78.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	pspE	GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K03972	-	-	-	-	ko00000	-	-	iE2348C_1286.E2348C_1500,iECABU_c1320.ECABU_c15910,iSDY_1059.SDY_1936,ic_1306.c1779	Rhodanese
CMS3_k127_2406244_16	1161401.ASJA01000018_gene1232	0.0006089	44.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,43XAY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS3_k127_2406244_3	667014.Thein_0860	8.369e-147	483.0	COG1206@1|root,COG1206@2|Bacteria,2GH7N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
CMS3_k127_2406244_6	1125863.JAFN01000001_gene2579	2.178e-63	230.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_2406244_7	517417.Cpar_1132	6.914e-62	220.0	COG5405@1|root,COG5405@2|Bacteria,1FDVZ@1090|Chlorobi	1090|Chlorobi	J	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS3_k127_2406244_1	338963.Pcar_2412	3.564e-180	583.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,43S1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS3_k127_2406244_11	882.DVU_2967	1.251e-13	84.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,2M8YC@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_2406244_5	243159.AFE_0256	3.524e-99	333.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,2NCF4@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_2406244_4	1128421.JAGA01000003_gene3154	2.175e-100	336.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_2406244_9	448385.sce2419	9.953e-20	105.0	COG0484@1|root,COG0484@2|Bacteria,1R0C7@1224|Proteobacteria,43CUM@68525|delta/epsilon subdivisions,2X82A@28221|Deltaproteobacteria,2Z3JM@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS3_k127_2406244_0	317655.Sala_2058	5.146e-202	641.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2K1KK@204457|Sphingomonadales	204457|Sphingomonadales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_2406244_15	1089552.KI911559_gene901	0.0004693	51.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	pleC	-	2.7.13.3	ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE4,GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
CMS3_k127_2406244_2	1125863.JAFN01000001_gene2585	2.872e-171	551.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS3_k127_2406244_10	107636.JQNK01000009_gene3014	2.02e-14	82.0	2DR4Y@1|root,32UQE@2|Bacteria,1RKGU@1224|Proteobacteria,2USCS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2406244_12	358220.C380_10965	2.58e-10	74.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2VJ6I@28216|Betaproteobacteria,4ABMZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM AsmA family protein	asmA	-	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
CMS3_k127_2406244_14	290633.GOX0244	2.1e-05	58.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2JSZ6@204441|Rhodospirillales	204441|Rhodospirillales	M	AsmA family	-	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
CMS3_k127_2406244_8	335541.Swol_1468	3.68e-56	211.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,2494Y@186801|Clostridia,42JPJ@68298|Syntrophomonadaceae	186801|Clostridia	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS3_k127_2415491_19	243231.GSU3378	8.406e-81	300.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS3_k127_2415491_35	1185876.BN8_02954	2.896e-38	155.0	COG1051@1|root,COG1051@2|Bacteria,4NNJ5@976|Bacteroidetes,47PUZ@768503|Cytophagia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_2415491_55	1283300.ATXB01000001_gene259	9.077e-06	56.0	2DGQ2@1|root,2ZWWE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2415491_17	1382303.JPOM01000001_gene1472	1.667e-87	299.0	COG1024@1|root,COG1024@2|Bacteria,1N4N7@1224|Proteobacteria,2TS6T@28211|Alphaproteobacteria,2KF8D@204458|Caulobacterales	204458|Caulobacterales	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_2415491_8	483219.LILAB_19595	3.191e-156	503.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2WMBS@28221|Deltaproteobacteria,2YWEV@29|Myxococcales	28221|Deltaproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
CMS3_k127_2415491_14	1229780.BN381_210057	4.288e-119	402.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.12	ko:K00248,ko:K14448	ko00071,ko00280,ko00630,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00630,map00650,map01100,map01110,map01120,map01200,map01212	M00373	R01175,R01178,R02661,R03172,R04751,R09293	RC00052,RC00068,RC00076,RC00120,RC00148,RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2415491_37	1500893.JQNB01000001_gene2226	1.025e-36	159.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,1RMVD@1236|Gammaproteobacteria,1X39H@135614|Xanthomonadales	135614|Xanthomonadales	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
CMS3_k127_2415491_43	1131269.AQVV01000011_gene2520	1.505e-29	120.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
CMS3_k127_2415491_25	573064.Mefer_0899	6.586e-50	185.0	COG2085@1|root,arCOG00457@2157|Archaea,2XUD2@28890|Euryarchaeota,23QAN@183939|Methanococci	183939|Methanococci	C	PFAM NADP oxidoreductase coenzyme F420-dependent	-	GO:0000041,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006826,GO:0008150,GO:0008152,GO:0008823,GO:0015677,GO:0015682,GO:0016020,GO:0016021,GO:0016491,GO:0016722,GO:0016723,GO:0030001,GO:0031224,GO:0031226,GO:0033216,GO:0034220,GO:0034755,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0052851,GO:0055085,GO:0055114,GO:0071944,GO:0072512,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098706,GO:0098711,GO:0098739,GO:0099587	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
CMS3_k127_2415491_0	1303518.CCALI_02898	0.0	1181.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
CMS3_k127_2415491_29	266117.Rxyl_0110	5.593e-46	179.0	COG2215@1|root,COG2215@2|Bacteria,2HRK4@201174|Actinobacteria,4CTM5@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2415491_22	330214.NIDE2543	3.643e-64	239.0	COG0616@1|root,COG0616@2|Bacteria,3J13W@40117|Nitrospirae	40117|Nitrospirae	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_2415491_57	44056.XP_009036673.1	7.541e-05	53.0	COG0483@1|root,KOG2951@2759|Eukaryota	2759|Eukaryota	G	Inositol-1-monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,EXS,Inositol_P
CMS3_k127_2415491_7	1519464.HY22_07040	1.878e-159	526.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1FEF9@1090|Chlorobi	1090|Chlorobi	C	electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
CMS3_k127_2415491_49	909663.KI867150_gene1264	1.145e-17	94.0	2C469@1|root,33HZ0@2|Bacteria,1NNDA@1224|Proteobacteria,42R4S@68525|delta/epsilon subdivisions,2WMQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2415491_27	1122939.ATUD01000002_gene1217	2.373e-47	181.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CQIT@84995|Rubrobacteria	84995|Rubrobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_2415491_31	713586.KB900536_gene1244	1.006e-40	169.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,1X2NF@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
CMS3_k127_2415491_52	309798.COPRO5265_0586	2.57e-11	74.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,42GIF@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
CMS3_k127_2415491_23	1120705.FG95_00406	4.925e-53	198.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VFDU@28211|Alphaproteobacteria,2K48Y@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_2415491_28	479434.Sthe_2447	3.255e-47	184.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi,27Z4S@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS3_k127_2415491_42	391625.PPSIR1_32929	5.662e-30	136.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YWN4@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2415491_58	258533.BN977_05985	0.0001022	54.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria,23B9T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_2415491_24	1125863.JAFN01000001_gene1051	5.361e-52	207.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS3_k127_2415491_48	667014.Thein_1303	1.046e-17	89.0	COG3215@1|root,COG3215@2|Bacteria,2GIKF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
CMS3_k127_2415491_26	502025.Hoch_5071	7.674e-49	186.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS3_k127_2415491_5	1232410.KI421421_gene3693	1.38e-167	558.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,43S8B@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_2415491_45	1123371.ATXH01000006_gene824	7.688e-25	114.0	COG2834@1|root,COG2834@2|Bacteria,2GGTM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
CMS3_k127_2415491_2	298653.Franean1_4882	1.251e-205	658.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4ERPJ@85013|Frankiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
CMS3_k127_2415491_3	671143.DAMO_0750	4.517e-181	584.0	COG4122@1|root,COG4122@2|Bacteria,2NQFB@2323|unclassified Bacteria	2|Bacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
CMS3_k127_2415491_53	671143.DAMO_0690	1.85e-09	63.0	2E9C2@1|root,30ZT9@2|Bacteria,2NRQ4@2323|unclassified Bacteria	2|Bacteria	S	Pup-like protein	-	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
CMS3_k127_2415491_20	58123.JOFJ01000006_gene264	7.415e-73	259.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4EFQB@85012|Streptosporangiales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
CMS3_k127_2415491_21	1499967.BAYZ01000184_gene4590	1.089e-66	248.0	COG0638@1|root,COG0638@2|Bacteria,2NQRX@2323|unclassified Bacteria	2|Bacteria	O	Proteasome subunit	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
CMS3_k127_2415491_6	671143.DAMO_0753	6.39e-164	527.0	COG0638@1|root,COG0638@2|Bacteria,2NQFW@2323|unclassified Bacteria	2|Bacteria	O	Pup-ligase protein	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
CMS3_k127_2415491_11	1192034.CAP_7535	9.422e-145	466.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_2415491_56	1121472.AQWN01000009_gene291	4.571e-05	56.0	COG3255@1|root,COG3255@2|Bacteria,1VFEY@1239|Firmicutes,24QXQ@186801|Clostridia,263BY@186807|Peptococcaceae	186801|Clostridia	I	sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_2415491_16	96561.Dole_0625	1.169e-87	307.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS3_k127_2415491_46	290397.Adeh_1232	1.196e-21	103.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS3_k127_2415491_38	1163409.UUA_08401	5.126e-34	141.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1X6TJ@135614|Xanthomonadales	135614|Xanthomonadales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CMS3_k127_2415491_18	867903.ThesuDRAFT_00190	3.216e-84	312.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WCJP@538999|Clostridiales incertae sedis	186801|Clostridia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS3_k127_2415491_10	338963.Pcar_2405	3.92e-151	488.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,43S46@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Rad51	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS3_k127_2415491_4	404589.Anae109_3433	1.095e-175	562.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_2415491_1	1232410.KI421428_gene1168	1.034e-291	921.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,43THC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_2415491_9	1519464.HY22_12680	3.27e-154	552.0	COG0821@1|root,COG0821@2|Bacteria,1FDH2@1090|Chlorobi	1090|Chlorobi	H	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS3_k127_2415491_54	525897.Dbac_0510	3.045e-07	59.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MDHW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS3_k127_2415491_36	1297742.A176_04111	4.783e-37	159.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
CMS3_k127_2415491_41	439235.Dalk_2404	2.798e-30	131.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2MJ58@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS3_k127_2415491_39	1340493.JNIF01000003_gene3662	1.495e-33	136.0	COG0558@1|root,COG0558@2|Bacteria,3Y427@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_2415491_50	665942.HMPREF1022_01094	5.016e-15	87.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MCVH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
CMS3_k127_2415491_32	1298858.AUEL01000001_gene4712	1.763e-40	163.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2TUFV@28211|Alphaproteobacteria,43HJ9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_2415491_33	243231.GSU0662	2.549e-40	160.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2WQIY@28221|Deltaproteobacteria,43UNV@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS3_k127_2415491_34	867845.KI911784_gene2048	4.218e-39	167.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi,375JU@32061|Chloroflexia	32061|Chloroflexia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS3_k127_2415491_15	1382356.JQMP01000003_gene2001	1.874e-90	316.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi,27Y0D@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
CMS3_k127_2415491_13	880073.Calab_3060	7.698e-122	398.0	COG0214@1|root,COG0214@2|Bacteria,2NNZ6@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
CMS3_k127_2415491_30	1285586.H131_00030	3.451e-43	169.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,3IWFK@400634|Lysinibacillus	91061|Bacilli	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
CMS3_k127_2415491_51	690850.Desaf_3206	5.054e-13	79.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2WRDG@28221|Deltaproteobacteria,2MCE6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS3_k127_2415491_47	1121405.dsmv_0366	9.052e-21	108.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,2MKM0@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS3_k127_2415491_40	404589.Anae109_0120	1.906e-32	133.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2YX0Q@29|Myxococcales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS3_k127_2415491_12	330214.NIDE3441	3.044e-124	415.0	COG0305@1|root,COG0305@2|Bacteria,3J0EZ@40117|Nitrospirae	40117|Nitrospirae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS3_k127_2415491_44	1341151.ASZU01000025_gene2986	2.591e-28	120.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,27B0F@186824|Thermoactinomycetaceae	91061|Bacilli	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
CMS3_k127_2419515_0	378806.STAUR_4691	1.582e-74	263.0	COG2518@1|root,COG2518@2|Bacteria,1QX9V@1224|Proteobacteria,42Z9X@68525|delta/epsilon subdivisions,2WUEX@28221|Deltaproteobacteria,2YX7N@29|Myxococcales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2419515_1	383372.Rcas_2471	5.939e-09	69.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2469611_2	525904.Tter_1226	2.284e-122	400.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
CMS3_k127_2469611_8	443144.GM21_2368	2.165e-33	143.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R7R@68525|delta/epsilon subdivisions,2WMT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_2469611_9	1535422.ND16A_2142	1.452e-27	119.0	COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,2Q6RN@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS3_k127_2469611_1	1120983.KB894575_gene537	8.991e-127	424.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,1JNFB@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
CMS3_k127_2469611_10	649831.L083_2639	2.968e-22	111.0	COG5285@1|root,COG5285@2|Bacteria,2H6U8@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_2469611_6	565033.GACE_0916	3.406e-58	222.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,245XG@183980|Archaeoglobi	183980|Archaeoglobi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_2469611_7	1038859.AXAU01000001_gene3169	8.104e-36	148.0	COG2227@1|root,COG2227@2|Bacteria,1RHSX@1224|Proteobacteria,2TWSI@28211|Alphaproteobacteria,3JXUH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_2469611_4	163908.KB235896_gene2246	1.264e-78	274.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria,1HMER@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS3_k127_2469611_12	1242864.D187_008608	2.769e-12	80.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_2469611_3	1125863.JAFN01000001_gene2073	4.667e-86	302.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_2469611_5	314285.KT71_04350	4.408e-72	263.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_2469611_14	711393.AYRX01000033_gene17	2.567e-05	56.0	COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	ypeA	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_2469611_13	1385515.N791_13340	1.159e-11	78.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X3NB@135614|Xanthomonadales	135614|Xanthomonadales	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2469611_11	452637.Oter_2407	4.551e-14	86.0	COG4191@1|root,COG4191@2|Bacteria,46W3V@74201|Verrucomicrobia,3K9SN@414999|Opitutae	414999|Opitutae	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS3_k127_2469611_0	330214.NIDE1585	9.881e-128	422.0	COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae	2|Bacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2499295_9	748280.NH8B_0882	9.638e-22	111.0	COG4625@1|root,COG4625@2|Bacteria,1PG9Q@1224|Proteobacteria,2WAGN@28216|Betaproteobacteria,2KTB2@206351|Neisseriales	206351|Neisseriales	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS3_k127_2499295_6	1207063.P24_01195	3.724e-50	196.0	296TN@1|root,2ZU2M@2|Bacteria,1RKK5@1224|Proteobacteria,2TYYP@28211|Alphaproteobacteria,2JW1U@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_2499295_4	47839.CCAU010000016_gene4461	3.198e-77	274.0	COG5361@1|root,COG5361@2|Bacteria,2IJJW@201174|Actinobacteria,23AAB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
CMS3_k127_2499295_7	460265.Mnod_1225	1.197e-29	137.0	COG1999@1|root,COG1999@2|Bacteria,1MZAW@1224|Proteobacteria,2U1D6@28211|Alphaproteobacteria,1JV5A@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_2499295_1	460265.Mnod_1226	2.548e-174	557.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,2TQRB@28211|Alphaproteobacteria,1JQZ4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
CMS3_k127_2499295_2	525368.HMPREF0591_3206	4.413e-160	513.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,235AT@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2499295_3	1122604.JONR01000048_gene1005	1.567e-79	279.0	COG1024@1|root,COG1024@2|Bacteria,1R5V7@1224|Proteobacteria,1S0FP@1236|Gammaproteobacteria,1X5A1@135614|Xanthomonadales	135614|Xanthomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2499295_0	1030157.AFMP01000028_gene2221	8.551e-182	587.0	COG0318@1|root,COG0318@2|Bacteria,1MXAV@1224|Proteobacteria,2U3TX@28211|Alphaproteobacteria,2K1RX@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2499295_8	1207055.C100_18010	3.38e-24	114.0	2ECT0@1|root,32RXS@2|Bacteria,1N6EY@1224|Proteobacteria,2UJ21@28211|Alphaproteobacteria,2K7TF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2499295_5	749927.AMED_7203	2.287e-56	203.0	COG1574@1|root,COG1574@2|Bacteria,2GKXR@201174|Actinobacteria,4E8QU@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_250749_0	1333998.M2A_2211	2.912e-167	540.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,4BT9B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS3_k127_250749_6	1294273.roselon_02522	1.458e-84	311.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	MA20_09415	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS3_k127_250749_11	1385935.N836_33000	1.801e-18	100.0	COG0500@1|root,COG2226@2|Bacteria,1GQNU@1117|Cyanobacteria,1HHXR@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_250749_7	883078.HMPREF9695_04109	4.546e-82	282.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2TTQ1@28211|Alphaproteobacteria,3JT0H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_19270	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_250749_8	1229780.BN381_80395	1.276e-77	285.0	COG1024@1|root,COG1024@2|Bacteria,2IAFJ@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_250749_1	1123320.KB889562_gene6741	6.534e-124	407.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_250749_3	479433.Caci_5229	2.377e-98	329.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_250749_9	1123320.KB889562_gene6675	1.351e-66	248.0	COG4221@1|root,COG4221@2|Bacteria,2IGP3@201174|Actinobacteria	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_250749_2	211165.AJLN01000033_gene2635	8.4e-107	374.0	COG2124@1|root,COG2124@2|Bacteria,1G57F@1117|Cyanobacteria,1JMVQ@1189|Stigonemataceae	1117|Cyanobacteria	Q	Cytochrome P450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
CMS3_k127_250749_10	1283300.ATXB01000001_gene1912	2.196e-63	236.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,1XF6V@135618|Methylococcales	135618|Methylococcales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS3_k127_250749_5	1449069.JMLO01000008_gene3497	1.421e-87	307.0	COG1028@1|root,COG1028@2|Bacteria,2GMAG@201174|Actinobacteria,4FU2T@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_250749_4	1382306.JNIM01000001_gene30	1.811e-89	304.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_2516949_5	525146.Ddes_1150	7.626e-15	78.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMIV@28221|Deltaproteobacteria,2MGEF@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_2516949_3	479434.Sthe_1410	5.941e-41	160.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi,27Y6D@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS3_k127_2516949_4	1094980.Mpsy_3179	2.06e-38	164.0	COG2386@1|root,arCOG01328@2157|Archaea,2XTAS@28890|Euryarchaeota,2NAJD@224756|Methanomicrobia	224756|Methanomicrobia	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CMS3_k127_2516949_2	1125863.JAFN01000001_gene3012	6.403e-42	178.0	COG1131@1|root,COG1131@2|Bacteria,1RGM1@1224|Proteobacteria,43ADE@68525|delta/epsilon subdivisions,2X5TA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CMS3_k127_2516949_7	309801.trd_0263	2.635e-07	66.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi,27XRI@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2516949_0	234267.Acid_4232	4.653e-165	541.0	COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS3_k127_2516949_6	867903.ThesuDRAFT_01602	1.079e-12	75.0	COG2332@1|root,COG2332@2|Bacteria,1VJ83@1239|Firmicutes,24W3E@186801|Clostridia	186801|Clostridia	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CMS3_k127_2516949_1	411464.DESPIG_01010	3.367e-108	372.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WJ0U@28221|Deltaproteobacteria,2M88V@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_2518518_4	1121920.AUAU01000005_gene982	1.707e-125	412.0	COG3214@1|root,COG3214@2|Bacteria,3Y96S@57723|Acidobacteria	57723|Acidobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
CMS3_k127_2518518_19	1217718.ALOU01000021_gene2384	5.721e-13	78.0	COG1309@1|root,COG1309@2|Bacteria,1RIG0@1224|Proteobacteria,2VYKM@28216|Betaproteobacteria,1K9ZF@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2518518_9	215803.DB30_4125	1.269e-80	282.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,439AV@68525|delta/epsilon subdivisions,2X4IJ@28221|Deltaproteobacteria,2YZ3A@29|Myxococcales	28221|Deltaproteobacteria	F	COG0208 Ribonucleotide reductase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2518518_0	1333998.M2A_2493	4.377e-206	696.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TV8M@28211|Alphaproteobacteria,4BTBG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2518518_15	1198232.CYCME_1431	3.45e-42	175.0	COG4745@1|root,COG4745@2|Bacteria,1P6CQ@1224|Proteobacteria	1224|Proteobacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2518518_2	314278.NB231_04135	8.877e-147	495.0	COG3660@1|root,COG3660@2|Bacteria,1R70U@1224|Proteobacteria,1S0W8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
CMS3_k127_2518518_16	1254432.SCE1572_11275	4.069e-32	130.0	2A4R8@1|root,30TCM@2|Bacteria,1PD5K@1224|Proteobacteria,43DYZ@68525|delta/epsilon subdivisions,2WZ8R@28221|Deltaproteobacteria,2Z1KF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS3_k127_2518518_1	649747.HMPREF0083_01416	4.523e-150	512.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,271Q2@186822|Paenibacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2518518_6	1479238.JQMZ01000001_gene1408	1.528e-95	319.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2U2R9@28211|Alphaproteobacteria,43XFU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_2518518_14	1499683.CCFF01000017_gene1572	4.057e-59	211.0	COG0740@1|root,COG0740@2|Bacteria,1V35G@1239|Firmicutes,24B2R@186801|Clostridia,36G5J@31979|Clostridiaceae	186801|Clostridia	OU	Clp protease	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
CMS3_k127_2518518_3	497964.CfE428DRAFT_6677	8.14e-126	422.0	COG2896@1|root,COG2896@2|Bacteria,46TG4@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Molybdenum Cofactor Synthesis C	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS3_k127_2518518_18	1144275.COCOR_01233	3.103e-13	80.0	2ARAZ@1|root,31GKZ@2|Bacteria,1NPW3@1224|Proteobacteria,43320@68525|delta/epsilon subdivisions,2WY42@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3332
CMS3_k127_2518518_8	391625.PPSIR1_08202	2.676e-84	295.0	KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_2518518_10	234267.Acid_1673	2.099e-80	306.0	COG0332@1|root,COG0332@2|Bacteria,3Y83G@57723|Acidobacteria	57723|Acidobacteria	H	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C
CMS3_k127_2518518_7	251221.35211586	4.869e-91	311.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_2518518_11	595460.RRSWK_03882	2.256e-78	292.0	COG3264@1|root,COG3264@2|Bacteria,2IY5W@203682|Planctomycetes	203682|Planctomycetes	M	COG3264 Small-conductance mechanosensitive channel	-	-	-	ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.2,1.A.23.1.3	-	-	MS_channel
CMS3_k127_2518518_5	1282876.BAOK01000001_gene2489	2.865e-123	406.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria,4BT9Y@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2518518_12	1121935.AQXX01000134_gene3585	6.671e-68	241.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1XJM0@135619|Oceanospirillales	135619|Oceanospirillales	C	Molybdenum cofactor sulfurase	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
CMS3_k127_2518518_20	479434.Sthe_2271	5.187e-07	63.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2518518_17	861299.J421_6000	5.745e-31	126.0	COG0789@1|root,COG0789@2|Bacteria,1ZVAN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	MerR, DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	-
CMS3_k127_2518518_13	1267535.KB906767_gene5244	1.648e-63	236.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
CMS3_k127_2519257_8	1380370.JIBA01000012_gene3930	1.727e-21	109.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria,4FI91@85021|Intrasporangiaceae	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CMS3_k127_2519257_0	1192034.CAP_3147	0.0	1227.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,2YUG5@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_2519257_5	670487.Ocepr_0115	3.133e-43	169.0	COG0697@1|root,COG0697@2|Bacteria,1WKUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2519257_1	1380394.JADL01000011_gene3947	2.439e-200	635.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRJV@28211|Alphaproteobacteria,2JP8V@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS3_k127_2519257_4	936455.KI421499_gene929	8.407e-71	247.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2U1NG@28211|Alphaproteobacteria,3JUW4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	MA20_45175	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS3_k127_2519257_7	66897.DJ64_27090	9.069e-23	111.0	COG0454@1|root,COG0456@2|Bacteria,2IHUH@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,CM_2
CMS3_k127_2519257_9	452637.Oter_0599	7.636e-19	102.0	COG0457@1|root,COG0457@2|Bacteria,46V1N@74201|Verrucomicrobia,3KA0R@414999|Opitutae	74201|Verrucomicrobia	M	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_2519257_10	886293.Sinac_0127	1.022e-05	57.0	COG2755@1|root,COG2755@2|Bacteria,2J1DW@203682|Planctomycetes	203682|Planctomycetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_2519257_6	1068978.AMETH_6012	2.757e-33	137.0	COG1309@1|root,COG1309@2|Bacteria,2IFMU@201174|Actinobacteria,4E3ZJ@85010|Pseudonocardiales	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_2519257_2	305900.GV64_04830	9.707e-159	528.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,1RRE0@1236|Gammaproteobacteria,1XPCU@135619|Oceanospirillales	135619|Oceanospirillales	Q	dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	RPE65
CMS3_k127_2519257_3	314278.NB231_11914	3.511e-73	278.0	COG3137@1|root,COG3137@2|Bacteria,1RCKQ@1224|Proteobacteria,1S0GK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS3_k127_2568822_2	1123023.JIAI01000002_gene4645	8.902e-121	415.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2568822_7	1173024.KI912148_gene3582	3.038e-56	205.0	COG0398@1|root,COG0398@2|Bacteria,1G3PG@1117|Cyanobacteria,1JJR5@1189|Stigonemataceae	1117|Cyanobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_2568822_1	179408.Osc7112_2732	2.037e-178	589.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1H7PH@1150|Oscillatoriales	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
CMS3_k127_2568822_8	1449355.JQNR01000005_gene5647	2.407e-52	194.0	COG3393@1|root,COG3393@2|Bacteria,2GMQC@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	FR47
CMS3_k127_2568822_5	314230.DSM3645_06149	6.541e-65	229.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2568822_10	1294273.roselon_03614	1.275e-27	119.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS3_k127_2568822_11	1267535.KB906767_gene3861	1.471e-27	122.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS3_k127_2568822_9	1254432.SCE1572_04375	6.53e-42	162.0	COG0467@1|root,COG0467@2|Bacteria,1RFBT@1224|Proteobacteria,42QWP@68525|delta/epsilon subdivisions,2WMB2@28221|Deltaproteobacteria,2YTTP@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2568822_0	1125863.JAFN01000001_gene1028	4.232e-318	986.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42NDG@68525|delta/epsilon subdivisions,2WKYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_2568822_4	8083.ENSXMAP00000005318	3.156e-67	241.0	COG1012@1|root,KOG2452@2759|Eukaryota,39MAJ@33154|Opisthokonta,3BCUT@33208|Metazoa,3CY12@33213|Bilateria,487KE@7711|Chordata,48XCX@7742|Vertebrata,49QTQ@7898|Actinopterygii	33208|Metazoa	F	Aldehyde dehydrogenase 1 family member L2	ALDH1L2	GO:0003674,GO:0003824,GO:0004029,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016155,GO:0016491,GO:0016620,GO:0016645,GO:0016646,GO:0016903,GO:0017144,GO:0019752,GO:0031974,GO:0034641,GO:0042558,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043648,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046655,GO:0051186,GO:0055114,GO:0070013,GO:0071704,GO:1901360,GO:1901564	1.5.1.6	ko:K00289	ko00670,map00670	-	R00941	RC00026	ko00000,ko00001,ko01000	-	-	-	Aldedh,Formyl_trans_C,Formyl_trans_N,PP-binding
CMS3_k127_2568822_13	1281779.H009_03408	9.694e-17	92.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,2U5F8@28211|Alphaproteobacteria,4B73D@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Acetyltransferase (Isoleucine patch superfamily)	nodL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008374,GO:0008925,GO:0009987,GO:0016043,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
CMS3_k127_2568822_12	264462.Bd0321	1.218e-19	92.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42WGE@68525|delta/epsilon subdivisions,2MUA5@213481|Bdellovibrionales,2WRF1@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS3_k127_2568822_6	1537715.JQFJ01000002_gene456	3.736e-58	232.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2568822_16	1261545.MBE-HAL_1358	4.987e-05	57.0	arCOG04615@1|root,arCOG04615@2157|Archaea,2XTCV@28890|Euryarchaeota,23SW9@183963|Halobacteria	183963|Halobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2568822_3	1125863.JAFN01000001_gene1039	2.945e-109	378.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS3_k127_2568822_14	1160707.AJIK01000042_gene2275	2.011e-11	75.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26FGX@186818|Planococcaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS3_k127_2582652_6	28072.Nos7524_3587	7.673e-28	122.0	2DNA8@1|root,32WEJ@2|Bacteria,1G8EE@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM PEP-CTERM protein sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS3_k127_2582652_7	694427.Palpr_2077	5.58e-07	61.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,2FVM1@200643|Bacteroidia	976|Bacteroidetes	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
CMS3_k127_2582652_4	1122137.AQXF01000002_gene522	1.146e-63	230.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2TQXV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_2582652_5	1197130.BAFM01000001_gene22	1.455e-42	177.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2582652_0	448385.sce6750	1.822e-140	454.0	COG4586@1|root,COG4586@2|Bacteria,1RA7G@1224|Proteobacteria,42RT3@68525|delta/epsilon subdivisions,2WNGM@28221|Deltaproteobacteria,2YU3C@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2582652_2	272134.KB731324_gene3159	1.65e-80	277.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_2582652_1	794903.OPIT5_16000	1.486e-89	302.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_2582652_3	1123257.AUFV01000013_gene2845	2.324e-72	250.0	COG1574@1|root,COG1574@2|Bacteria,1R7BE@1224|Proteobacteria,1RYMV@1236|Gammaproteobacteria,1X5K8@135614|Xanthomonadales	135614|Xanthomonadales	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_2596911_20	192952.MM_2210	7.072e-22	108.0	COG1287@1|root,arCOG02043@2157|Archaea,2XX8Q@28890|Euryarchaeota,2NADZ@224756|Methanomicrobia	224756|Methanomicrobia	M	Oligosaccharyl transferase STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
CMS3_k127_2596911_17	1463854.JOHT01000011_gene4334	1.217e-43	172.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
CMS3_k127_2596911_10	1116232.AHBF01000060_gene3260	5.566e-98	331.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
CMS3_k127_2596911_9	861299.J421_0290	1.053e-103	356.0	COG0845@1|root,COG0845@2|Bacteria,1ZUP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_2596911_12	234267.Acid_6481	1.903e-93	344.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2596911_2	1278073.MYSTI_07741	2.486e-152	522.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_2596911_1	234267.Acid_4168	4.992e-180	574.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2596911_4	452637.Oter_1902	2.195e-136	449.0	COG5000@1|root,COG5000@2|Bacteria,46V9C@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS3_k127_2596911_0	1348657.M622_02895	1.278e-192	615.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJBJ@28216|Betaproteobacteria,2KVC5@206389|Rhodocyclales	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2596911_14	404589.Anae109_3083	6.395e-63	222.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2YVW1@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
CMS3_k127_2596911_19	298654.FraEuI1c_3575	3.71e-36	144.0	COG3467@1|root,COG3467@2|Bacteria,2I5VH@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_2596911_11	391625.PPSIR1_02206	8.476e-97	338.0	COG0477@1|root,COG2814@2|Bacteria,1R590@1224|Proteobacteria,42P8I@68525|delta/epsilon subdivisions,2WKQ6@28221|Deltaproteobacteria,2YX09@29|Myxococcales	28221|Deltaproteobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2596911_18	1150599.MPHLEI_16236	4.627e-42	165.0	COG4221@1|root,COG4221@2|Bacteria,2GK52@201174|Actinobacteria,23684@1762|Mycobacteriaceae	201174|Actinobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2596911_23	1187851.A33M_3582	0.0001008	54.0	COG3637@1|root,COG3637@2|Bacteria,1MVJR@1224|Proteobacteria,2TY44@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Opacity protein and related surface antigens	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS3_k127_2596911_15	396588.Tgr7_0225	1.69e-54	216.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WWUD@135613|Chromatiales	135613|Chromatiales	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_2596911_8	1415780.JPOG01000001_gene2856	3.425e-105	351.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X42D@135614|Xanthomonadales	135614|Xanthomonadales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
CMS3_k127_2596911_13	1122604.JONR01000015_gene187	1.275e-81	287.0	COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,1X71G@135614|Xanthomonadales	135614|Xanthomonadales	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CMS3_k127_2596911_22	1123279.ATUS01000003_gene528	1.905e-08	65.0	2DIKV@1|root,303K3@2|Bacteria,1PI5E@1224|Proteobacteria,1TFEX@1236|Gammaproteobacteria,1JBJH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CMS3_k127_2596911_16	1123073.KB899241_gene1965	2.438e-44	168.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1X8MB@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_2596911_5	1278073.MYSTI_00285	1.513e-134	458.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WKBG@28221|Deltaproteobacteria,2YYAD@29|Myxococcales	28221|Deltaproteobacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
CMS3_k127_2596911_7	626887.J057_16740	1.729e-120	401.0	28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2596911_6	1042377.AFPJ01000028_gene2158	1.811e-121	430.0	COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS3_k127_2596911_3	1049564.TevJSym_aj00030	3.632e-137	479.0	2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,1J916@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2596911_21	96561.Dole_1236	1.239e-18	93.0	2EV1P@1|root,33NGS@2|Bacteria,1NNNK@1224|Proteobacteria,42Y1H@68525|delta/epsilon subdivisions,2WSVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2619884_17	56780.SYN_02458	7.322e-13	73.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MM@1224|Proteobacteria,42X37@68525|delta/epsilon subdivisions,2WSNI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS3_k127_2619884_12	243231.GSU1765	1.69e-60	218.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43UK9@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_2619884_1	1121405.dsmv_2787	2.437e-194	630.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MI30@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS3_k127_2619884_11	483219.LILAB_31150	1.605e-61	241.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS3_k127_2619884_6	234267.Acid_4056	4.092e-101	345.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.2.17,5.1.3.4	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS3_k127_2619884_2	266834.SMc02321	1.583e-189	602.0	COG4952@1|root,COG4952@2|Bacteria,1PSSV@1224|Proteobacteria,2TSCI@28211|Alphaproteobacteria,4B7PG@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	sugar isomerase	rhaI	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_2619884_0	357808.RoseRS_2735	1.346e-271	883.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi,376HX@32061|Chloroflexia	32061|Chloroflexia	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS3_k127_2619884_5	1502852.FG94_02245	1.087e-111	376.0	COG1070@1|root,COG1070@2|Bacteria,1MUHF@1224|Proteobacteria,2VNPB@28216|Betaproteobacteria,473VH@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	fucK	-	-	-	-	-	-	-	-	-	-	-	FGGY_N
CMS3_k127_2619884_4	272559.BF9343_3621	2.471e-116	398.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,2FP6T@200643|Bacteroidia,4AKST@815|Bacteroidaceae	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_2619884_13	1469245.JFBG01000071_gene66	2.672e-52	212.0	COG0457@1|root,COG0457@2|Bacteria,1N8DP@1224|Proteobacteria,1SDM6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2619884_3	314345.SPV1_05437	3.476e-170	586.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria	1224|Proteobacteria	S	A circularly permuted ATPgrasp	MA20_32420	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
CMS3_k127_2619884_10	314345.SPV1_05442	9.838e-64	231.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CMS3_k127_2619884_9	314345.SPV1_05447	8.041e-70	259.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria	1224|Proteobacteria	E	Transglutaminase	MA20_32430	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
CMS3_k127_2619884_7	665571.STHERM_c16570	1.479e-89	319.0	COG0788@1|root,COG0788@2|Bacteria,2J7GR@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
CMS3_k127_2619884_14	1324957.K933_02031	2.214e-38	156.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XU61@28890|Euryarchaeota,23TWQ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2619884_8	1121920.AUAU01000033_gene2765	1.324e-83	310.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,3Y6AK@57723|Acidobacteria	57723|Acidobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_2619884_16	313606.M23134_06976	6.34e-30	122.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,47QAX@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS3_k127_2619884_15	1173263.Syn7502_01234	7.314e-31	130.0	COG1104@1|root,COG1104@2|Bacteria,1G0D5@1117|Cyanobacteria,1GYPR@1129|Synechococcus	1117|Cyanobacteria	E	COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_2626077_0	1238182.C882_4198	2.195e-206	661.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U0QC@28211|Alphaproteobacteria,2JQ41@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_2626077_4	1137799.GZ78_02265	2.519e-80	292.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XI5Y@135619|Oceanospirillales	135619|Oceanospirillales	C	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
CMS3_k127_2626077_21	1504981.KO116_3440	2.754e-06	58.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,1S3W5@1236|Gammaproteobacteria,1XMKR@135619|Oceanospirillales	135619|Oceanospirillales	C	Fumarate reductase subunit D	-	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_D
CMS3_k127_2626077_18	316055.RPE_2586	4.898e-12	78.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2U5MT@28211|Alphaproteobacteria,3JXKV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_2626077_6	861299.J421_1548	5.04e-78	273.0	COG3826@1|root,COG3826@2|Bacteria	2|Bacteria	S	Oxygenase, catalysing oxidative methylation of damaged DNA	-	-	-	ko:K09990	-	-	-	-	ko00000	-	-	-	Oxygenase-NA
CMS3_k127_2626077_15	243233.MCA1644	2.031e-18	91.0	COG0271@1|root,COG0271@2|Bacteria,1QCDN@1224|Proteobacteria,1THS7@1236|Gammaproteobacteria,1XFIA@135618|Methylococcales	135618|Methylococcales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
CMS3_k127_2626077_8	1047013.AQSP01000106_gene1773	3.498e-47	194.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS3_k127_2626077_19	439496.RBY4I_254	6.526e-09	68.0	COG1401@1|root,COG1637@1|root,COG1401@2|Bacteria,COG1637@2|Bacteria,1NA4I@1224|Proteobacteria	1224|Proteobacteria	L	Pfam:DUF91	-	-	-	ko:K07448,ko:K07503	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	NucS
CMS3_k127_2626077_3	247633.GP2143_06654	3.683e-91	328.0	COG3386@1|root,COG3386@2|Bacteria,1QN8Y@1224|Proteobacteria,1S5PU@1236|Gammaproteobacteria,1J7F2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS3_k127_2626077_10	1437882.AZRU01000102_gene3871	1.498e-41	168.0	COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria,1YI8A@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	phosphoesterase DHHA1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
CMS3_k127_2626077_22	1499967.BAYZ01000105_gene3516	2.731e-05	51.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS3_k127_2626077_1	886293.Sinac_5818	3.169e-109	368.0	COG1696@1|root,COG1696@2|Bacteria,2IX06@203682|Planctomycetes	203682|Planctomycetes	M	membrane protein involved in D-alanine	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_2626077_5	1047013.AQSP01000084_gene767	1.407e-78	277.0	COG1145@1|root,COG1456@1|root,COG1145@2|Bacteria,COG1456@2|Bacteria	2|Bacteria	C	acetyl-CoA catabolic process	acsC	-	1.3.1.1,1.3.98.1,2.1.1.245	ko:K00197,ko:K00226,ko:K08941,ko:K17723	ko00240,ko00410,ko00680,ko00720,ko00770,ko01100,ko01120,ko01200,map00240,map00410,map00680,map00720,map00770,map01100,map01120,map01200	M00046,M00051,M00357,M00377,M00422,M00598	R00977,R01414,R01867,R09096,R10219,R10243,R11026	RC00004,RC00051,RC00072,RC00113,RC00123,RC02977	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CdhD,DHO_dh,FeS,Fer4
CMS3_k127_2626077_12	1417296.U879_03685	1.703e-30	136.0	COG0500@1|root,COG2226@2|Bacteria,1R41W@1224|Proteobacteria,2UJDA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_2626077_20	1192034.CAP_7583	6.788e-09	65.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WXCH@28221|Deltaproteobacteria,2Z381@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_2626077_2	479432.Sros_6142	6.681e-96	331.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EHHD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2626077_14	1137271.AZUM01000004_gene4305	1.073e-20	109.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria,4E1MR@85010|Pseudonocardiales	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2626077_17	1242864.D187_006518	4.199e-12	79.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_2626077_9	1324957.K933_00557	1.281e-46	187.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_2626077_11	261292.Nit79A3_1073	1.252e-31	145.0	COG0652@1|root,COG0652@2|Bacteria,1RCXX@1224|Proteobacteria,2WD5W@28216|Betaproteobacteria,373YC@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM Peptidyl-prolyl cis-trans isomerase, cyclophilin-type	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_2626077_13	1201288.M900_0885	5.317e-25	122.0	2BHTE@1|root,32BX2@2|Bacteria,1Q0YT@1224|Proteobacteria,432CX@68525|delta/epsilon subdivisions,2WYDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2626077_7	1313172.YM304_01450	1.437e-67	251.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4CN78@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_2626077_16	760568.Desku_2268	3.305e-13	77.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26020@186807|Peptococcaceae	186801|Clostridia	EH	Anthranilate synthase component I	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
CMS3_k127_2654321_4	240015.ACP_1386	3.672e-67	241.0	COG2103@1|root,COG2103@2|Bacteria,3Y378@57723|Acidobacteria,2JHNG@204432|Acidobacteriia	204432|Acidobacteriia	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS_2
CMS3_k127_2654321_5	1177928.TH2_06991	1.099e-15	81.0	2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,2UFRY@28211|Alphaproteobacteria,2JUKX@204441|Rhodospirillales	204441|Rhodospirillales	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
CMS3_k127_2654321_1	760192.Halhy_1845	6.148e-132	433.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2654321_3	404589.Anae109_0005	1.285e-99	359.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_2654321_0	644282.Deba_1726	1.093e-139	467.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS3_k127_2654321_2	1138822.PL11_09950	3.834e-117	407.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
CMS3_k127_2733880_3	1121479.AUBS01000033_gene303	0.0009976	49.0	COG3391@1|root,COG4257@1|root,COG3391@2|Bacteria,COG4257@2|Bacteria,1PXBC@1224|Proteobacteria,2TURE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,SGL
CMS3_k127_2733880_0	298654.FraEuI1c_5088	8.289e-127	418.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria	201174|Actinobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_2733880_1	1297742.A176_02271	1.445e-98	357.0	COG0745@1|root,COG0784@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2Z2WF@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_2733880_2	318161.Sden_1471	1.534e-19	94.0	293WK@1|root,2ZRBR@2|Bacteria,1PBHQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2736440_38	616991.JPOO01000001_gene3364	4.754e-05	45.0	COG0500@1|root,COG2226@2|Bacteria,4NP7E@976|Bacteroidetes,1I1YN@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_2736440_31	1219080.VEZ01S_44_00430	3.459e-11	68.0	COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RQPV@1236|Gammaproteobacteria,1XTNF@135623|Vibrionales	135623|Vibrionales	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_2736440_24	1500890.JQNL01000001_gene1280	1.514e-38	150.0	2CYY5@1|root,32T55@2|Bacteria,1N3B2@1224|Proteobacteria,1SB28@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2736440_13	47839.CCAU010000002_gene2579	8.325e-88	294.0	2BHD5@1|root,32BF1@2|Bacteria,2GUXJ@201174|Actinobacteria,2383B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_2736440_34	1284352.AOIG01000011_gene1366	1.9e-09	67.0	COG0346@1|root,COG0346@2|Bacteria,1VP7J@1239|Firmicutes,4HVYV@91061|Bacilli,26XIC@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
CMS3_k127_2736440_26	666685.R2APBS1_3163	3.111e-35	147.0	COG3686@1|root,COG3686@2|Bacteria,1N00R@1224|Proteobacteria,1S7JA@1236|Gammaproteobacteria,1X7NQ@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS3_k127_2736440_29	323848.Nmul_A2100	1.188e-21	105.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2W4YS@28216|Betaproteobacteria,373E5@32003|Nitrosomonadales	28216|Betaproteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_2736440_25	331869.BAL199_02244	1.752e-37	145.0	COG0454@1|root,COG0456@2|Bacteria,1RIBM@1224|Proteobacteria,2UBNA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2736440_30	335543.Sfum_0165	8.436e-19	101.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2MS1V@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2736440_21	443144.GM21_2378	1.347e-47	198.0	COG4249@1|root,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
CMS3_k127_2736440_27	1173026.Glo7428_3652	2.629e-26	128.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria	1117|Cyanobacteria	S	Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
CMS3_k127_2736440_1	1282876.BAOK01000002_gene536	5.165e-193	610.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,4BPRD@82117|unclassified Alphaproteobacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2736440_23	502025.Hoch_4296	2.937e-41	160.0	COG4270@1|root,COG4270@2|Bacteria,1NAUW@1224|Proteobacteria,4385E@68525|delta/epsilon subdivisions,2X3FE@28221|Deltaproteobacteria,2YVUU@29|Myxococcales	28221|Deltaproteobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS3_k127_2736440_28	9823.ENSSSCP00000014796	1.747e-25	124.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,480TD@7711|Chordata,494JZ@7742|Vertebrata,3J3CH@40674|Mammalia,4J30Y@91561|Cetartiodactyla	33208|Metazoa	T	Cartilage oligomeric matrix protein	COMP	GO:0001501,GO:0001968,GO:0002020,GO:0003416,GO:0003417,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005912,GO:0005924,GO:0005927,GO:0007155,GO:0007275,GO:0007517,GO:0008150,GO:0008201,GO:0008289,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010941,GO:0016043,GO:0016203,GO:0019842,GO:0019899,GO:0022610,GO:0030054,GO:0030055,GO:0030198,GO:0031012,GO:0032501,GO:0032502,GO:0032991,GO:0033627,GO:0035265,GO:0036094,GO:0040007,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043394,GO:0043395,GO:0044421,GO:0044877,GO:0046872,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048705,GO:0048731,GO:0048736,GO:0048856,GO:0050789,GO:0050794,GO:0051216,GO:0060173,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060538,GO:0060548,GO:0061061,GO:0061448,GO:0062023,GO:0065007,GO:0070161,GO:0071840,GO:0097159,GO:0097367,GO:0098868,GO:1901681	-	ko:K04659,ko:K16857	ko04015,ko04115,ko04145,ko04151,ko04350,ko04510,ko04512,ko05144,ko05165,ko05205,ko05206,ko05219,map04015,map04115,map04145,map04151,map04350,map04510,map04512,map05144,map05165,map05205,map05206,map05219	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04147,ko04516	-	-	-	COMP,EGF_CA,TSP_3,TSP_C
CMS3_k127_2736440_35	1306990.BARG01000037_gene4358	1.245e-07	66.0	COG1409@1|root,COG1409@2|Bacteria,2GNU9@201174|Actinobacteria	201174|Actinobacteria	V	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos
CMS3_k127_2736440_19	1380386.JIAW01000007_gene3956	4.536e-58	218.0	COG1946@1|root,COG1946@2|Bacteria,2GZFD@201174|Actinobacteria,236Q9@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
CMS3_k127_2736440_17	1282876.BAOK01000002_gene517	3.699e-62	240.0	COG0518@1|root,COG0518@2|Bacteria,1Q2PQ@1224|Proteobacteria,2U196@28211|Alphaproteobacteria,4BS3A@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS3_k127_2736440_9	1282876.BAOK01000002_gene518	2.219e-99	334.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,4BQDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_2736440_4	204669.Acid345_1131	6.037e-141	458.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria,2JIRM@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2736440_14	1174528.JH992898_gene3099	1.874e-86	325.0	COG4485@1|root,COG4485@2|Bacteria,1GGV1@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2736440_20	1267535.KB906767_gene5001	1.126e-47	197.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_2736440_36	2074.JNYD01000003_gene3738	3.876e-07	64.0	COG4319@1|root,COG4319@2|Bacteria,2H0AV@201174|Actinobacteria,4EC4G@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS3_k127_2736440_6	1205680.CAKO01000007_gene4342	1.133e-115	404.0	COG0625@1|root,COG0625@2|Bacteria,1Q9ND@1224|Proteobacteria,2TT22@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
CMS3_k127_2736440_12	1313172.YM304_08620	3.146e-88	320.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_2736440_37	861299.J421_2404	3.313e-06	60.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2736440_18	402881.Plav_1965	9.184e-61	222.0	COG0346@1|root,COG0346@2|Bacteria,1R9XW@1224|Proteobacteria,2U6IT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
CMS3_k127_2736440_15	745310.G432_04685	1.087e-81	295.0	COG1028@1|root,COG1028@2|Bacteria,1Q737@1224|Proteobacteria,2UAE9@28211|Alphaproteobacteria,2K3B4@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2736440_22	575540.Isop_3045	5.402e-43	175.0	COG0457@1|root,COG0457@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_2736440_33	502025.Hoch_2288	1.781e-09	69.0	2DZX2@1|root,32VM6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2736440_3	1047013.AQSP01000067_gene2201	7.846e-142	501.0	COG3379@1|root,COG3379@2|Bacteria,2NQIG@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_2736440_0	1267535.KB906767_gene5241	2.168e-208	674.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_2736440_7	710687.KI912270_gene797	2.442e-113	388.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,235W7@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2736440_16	1041522.MCOL_V224197	4.771e-69	261.0	COG1960@1|root,COG1960@2|Bacteria,2HXD5@201174|Actinobacteria,235J6@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_2736440_10	243090.RB950	4.388e-91	318.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_2736440_2	298654.FraEuI1c_2032	1.711e-184	586.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_2736440_11	298654.FraEuI1c_4209	2.404e-90	314.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_2736440_8	330214.NIDE0204	9.331e-101	358.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,3J13F@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
CMS3_k127_2736440_5	383372.Rcas_4411	1.519e-127	426.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS3_k127_2755353_1	1306406.ASHX01000002_gene5094	1.935e-07	64.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_2755353_0	1123320.KB889685_gene2187	7.763e-62	220.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2757049_5	502025.Hoch_3368	6.42e-08	61.0	COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YZZW@29|Myxococcales	28221|Deltaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_2757049_4	158190.SpiGrapes_2239	6.086e-11	76.0	COG2834@1|root,COG2834@2|Bacteria,2JBH0@203691|Spirochaetes	203691|Spirochaetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_2757049_3	247634.GPB2148_1185	9.218e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,1S3TR@1236|Gammaproteobacteria,1J5M3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2757049_0	1254432.SCE1572_30680	1.752e-255	813.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2YWK3@29|Myxococcales	28221|Deltaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS3_k127_2757049_1	1168065.DOK_16538	1.964e-166	566.0	COG0304@1|root,COG0304@2|Bacteria,1R2NH@1224|Proteobacteria,1SEJN@1236|Gammaproteobacteria,1J6XZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	beta-ketoacyl-acyl-carrier-protein synthase II activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2757049_2	316067.Geob_0411	1.631e-87	310.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,42S5J@68525|delta/epsilon subdivisions,2WNJC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_2777984_2	118163.Ple7327_0472	3.186e-38	164.0	29N3X@1|root,3091P@2|Bacteria,1G154@1117|Cyanobacteria,3VM7V@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2777984_0	1380393.JHVP01000003_gene1268	3.998e-135	445.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
CMS3_k127_2777984_3	1333998.M2A_0707	1.238e-37	162.0	COG1680@1|root,COG1680@2|Bacteria,1RIYG@1224|Proteobacteria,2UC0Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_2777984_5	395965.Msil_1418	1.513e-21	111.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3NCQR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS3_k127_2777984_1	1463895.JODA01000003_gene898	6.216e-53	214.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
CMS3_k127_2777984_4	649638.Trad_1760	1.249e-25	119.0	29XYR@1|root,30JRD@2|Bacteria,1WNBY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
CMS3_k127_2832697_2	114615.BRADO3022	1.669e-41	158.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,3JSG0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Belongs to the ABC transporter superfamily	MA20_14335	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS3_k127_2832697_0	518766.Rmar_0089	0.0	1172.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_2832697_4	1125863.JAFN01000001_gene588	3.293e-25	120.0	COG2804@1|root,COG2804@2|Bacteria,1P3WC@1224|Proteobacteria,43207@68525|delta/epsilon subdivisions,2WWBT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
CMS3_k127_2832697_1	1125863.JAFN01000001_gene543	9.196e-45	183.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2832697_3	1242864.D187_001786	2.39e-35	140.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2834898_21	1237149.C900_05014	4.998e-16	82.0	2DQF9@1|root,336H4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2834898_18	204669.Acid345_3584	9.277e-29	122.0	COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2834898_19	1157708.KB907453_gene4070	2.626e-22	103.0	COG0346@1|root,COG0346@2|Bacteria,1NI3B@1224|Proteobacteria,2VYHQ@28216|Betaproteobacteria,4AHMG@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2834898_13	404589.Anae109_2821	2.725e-41	155.0	COG3791@1|root,COG3791@2|Bacteria,1N7AZ@1224|Proteobacteria	1224|Proteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_2834898_16	493475.GARC_1156	4.56e-35	138.0	COG3788@1|root,COG3788@2|Bacteria,1NBHH@1224|Proteobacteria,1SBVZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS3_k127_2834898_28	765698.Mesci_1811	0.0001224	52.0	COG2940@1|root,COG2940@2|Bacteria,1N3VM@1224|Proteobacteria,2UDY0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG2940 Proteins containing SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
CMS3_k127_2834898_5	698761.RTCIAT899_CH04575	1.024e-53	191.0	COG0346@1|root,COG0346@2|Bacteria,1PW4X@1224|Proteobacteria,2V7BJ@28211|Alphaproteobacteria,4BHUY@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2834898_22	176275.XP_008593404.1	1.519e-13	77.0	28KF5@1|root,2T3T9@2759|Eukaryota,38XM3@33154|Opisthokonta,3PX51@4751|Fungi,3RG4K@4890|Ascomycota,21DGY@147550|Sordariomycetes,3TJKN@5125|Hypocreales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2834898_15	47839.CCAU010000011_gene5825	1.455e-37	149.0	2B7DV@1|root,320HI@2|Bacteria,2IQBC@201174|Actinobacteria,23AVJ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2781
CMS3_k127_2834898_3	247639.MGP2080_01185	3.155e-93	323.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,1J50U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	caiD	GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006575,GO:0006577,GO:0006579,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0008809,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009437,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0034641,GO:0042178,GO:0042219,GO:0042221,GO:0042413,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097164,GO:0098754,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	4.2.1.149,4.2.1.17,5.3.3.18	ko:K01692,ko:K08299,ko:K15866	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R09837,R09839,R10675	RC00004,RC00326,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1945,iEC042_1314.EC042_0038,iECABU_c1320.ECABU_c00410,iECB_1328.ECB_00040,iECD_1391.ECD_00040,iECO103_1326.ECO103_0038,iECP_1309.ECP_0036,iETEC_1333.ETEC_0036,iNRG857_1313.NRG857_00190,iUMN146_1321.UM146_22960,ic_1306.c0045	ECH_1
CMS3_k127_2834898_20	196162.Noca_2363	7.754e-20	102.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4DQ6C@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	adh	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_2834898_7	215803.DB30_6914	2.061e-49	187.0	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,43811@68525|delta/epsilon subdivisions,2X3B3@28221|Deltaproteobacteria,2YV70@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
CMS3_k127_2834898_1	1463841.JOIR01000022_gene3281	6.818e-123	404.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
CMS3_k127_2834898_6	287.DR97_5978	4.861e-52	190.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
CMS3_k127_2834898_12	1463887.KL590016_gene6352	1.493e-42	173.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria	201174|Actinobacteria	S	beta-lactamase domain protein	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_2834898_25	1117315.AHCA01000012_gene2720	4.15e-07	62.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,2Q2CW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
CMS3_k127_2834898_26	456442.Mboo_0559	4.286e-07	57.0	COG0454@1|root,arCOG00839@2157|Archaea,2Y20T@28890|Euryarchaeota,2NB2F@224756|Methanomicrobia	224756|Methanomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS3_k127_2834898_0	1440053.JOEI01000002_gene3595	1.012e-124	414.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1,MFS_1_like
CMS3_k127_2834898_11	82996.sch_10390	2.652e-44	171.0	COG0388@1|root,COG0388@2|Bacteria,1RKC7@1224|Proteobacteria,1S4EA@1236|Gammaproteobacteria,403JS@613|Serratia	1236|Gammaproteobacteria	H	Carbon-nitrogen hydrolase	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS3_k127_2834898_8	1333998.M2A_0572	5.247e-49	180.0	COG0346@1|root,COG0346@2|Bacteria,1N3A9@1224|Proteobacteria	1224|Proteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2834898_9	1535422.ND16A_2476	2.303e-48	177.0	COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,1S7IY@1236|Gammaproteobacteria,2Q76T@267889|Colwelliaceae	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2834898_10	1068978.AMETH_3631	4.638e-48	184.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_2834898_14	1469245.JFBG01000026_gene1565	3.182e-38	147.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,1WYP7@135613|Chromatiales	135613|Chromatiales	S	PFAM glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_2834898_17	767029.HMPREF9154_2613	2.045e-31	129.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,MarR,MarR_2
CMS3_k127_2834898_23	756272.Plabr_3997	1.251e-08	68.0	COG3011@1|root,COG3011@2|Bacteria,2IYVQ@203682|Planctomycetes	203682|Planctomycetes	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
CMS3_k127_2834898_2	298654.FraEuI1c_5510	1.015e-103	352.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_2834898_4	1122604.JONR01000009_gene2314	1.782e-88	302.0	COG1028@1|root,COG1028@2|Bacteria,1QTUD@1224|Proteobacteria,1T1HG@1236|Gammaproteobacteria,1X5CZ@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2834898_24	232348.ADXL01000039_gene1654	2.884e-08	64.0	COG0685@1|root,COG0685@2|Bacteria,1G0GF@1117|Cyanobacteria,1GZ5U@1129|Synechococcus	1117|Cyanobacteria	C	reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_2848016_34	1463854.JOHT01000005_gene489	3.853e-63	237.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2848016_31	1463854.JOHT01000005_gene490	3.073e-66	250.0	COG1960@1|root,COG1960@2|Bacteria,2ID1K@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_2848016_26	1123321.KB905813_gene1522	7.33e-69	249.0	COG1960@1|root,COG1960@2|Bacteria,2HMS6@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
CMS3_k127_2848016_15	1122214.AQWH01000021_gene3195	4.969e-116	421.0	COG1960@1|root,COG1960@2|Bacteria,1Q2YE@1224|Proteobacteria,2TSY2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2848016_11	1150599.MPHLEI_16176	6.36e-147	502.0	COG0318@1|root,COG0318@2|Bacteria,2GK1Y@201174|Actinobacteria,236Q2@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2848016_10	614083.AWQR01000006_gene306	6.159e-149	482.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VKDB@28216|Betaproteobacteria,4ACMZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA_1	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS3_k127_2848016_29	502025.Hoch_0050	2.066e-67	246.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YYJX@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2848016_14	557599.MKAN_07645	8.122e-117	390.0	COG2124@1|root,COG2124@2|Bacteria,2GKKN@201174|Actinobacteria,23477@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.15.13	ko:K17474	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
CMS3_k127_2848016_0	557599.MKAN_03715	0.0	1375.0	COG0111@1|root,COG0235@1|root,COG1070@1|root,COG0111@2|Bacteria,COG0235@2|Bacteria,COG1070@2|Bacteria,2GIZV@201174|Actinobacteria,23EW1@1762|Mycobacteriaceae	201174|Actinobacteria	EGH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.399,1.1.1.95,2.7.1.189	ko:K00058,ko:K11216	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko02024,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map02024	M00020	R01513,R11183	RC00002,RC00017,RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,Aldolase_II,SCP2
CMS3_k127_2848016_57	502025.Hoch_5602	1.802e-22	115.0	COG3011@1|root,COG3011@2|Bacteria,1N0YV@1224|Proteobacteria,42VUX@68525|delta/epsilon subdivisions,2WW8H@28221|Deltaproteobacteria,2Z1U7@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS3_k127_2848016_13	1469245.JFBG01000027_gene1490	2.044e-121	409.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS3_k127_2848016_50	870187.Thini_0382	1.952e-29	131.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales	72273|Thiotrichales	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
CMS3_k127_2848016_1	118168.MC7420_1840	1.224e-285	895.0	COG0339@1|root,COG0339@2|Bacteria,1G05V@1117|Cyanobacteria,1H8PG@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Peptidase family M3	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS3_k127_2848016_20	305900.GV64_18055	1.578e-97	340.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1T3SF@1236|Gammaproteobacteria,1XP4Q@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS3_k127_2848016_53	660470.Theba_0308	3.057e-25	121.0	COG2035@1|root,COG2035@2|Bacteria,2GDA0@200918|Thermotogae	200918|Thermotogae	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
CMS3_k127_2848016_3	1121937.AUHJ01000001_gene682	4.304e-238	752.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2848016_35	1120972.AUMH01000010_gene329	2.12e-60	218.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,278I2@186823|Alicyclobacillaceae	91061|Bacilli	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_2848016_33	1121428.DESHY_160224___1	2.642e-65	240.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,260K8@186807|Peptococcaceae	186801|Clostridia	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS3_k127_2848016_18	1089553.Tph_c28840	2.456e-98	354.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,42GHF@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM cation transporter	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS3_k127_2848016_44	1125863.JAFN01000001_gene758	4.054e-43	177.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS3_k127_2848016_36	243231.GSU1832	1.036e-53	202.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS3_k127_2848016_42	1128421.JAGA01000002_gene1545	3.486e-45	187.0	COG0617@1|root,COG0617@2|Bacteria	2|Bacteria	J	CTP:tRNA cytidylyltransferase activity	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd
CMS3_k127_2848016_23	1232410.KI421413_gene502	2.051e-79	277.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,43TES@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	integrase domain protein SAM domain protein	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_2848016_6	316067.Geob_2763	1.198e-181	618.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
CMS3_k127_2848016_30	1125863.JAFN01000001_gene3499	1.931e-66	259.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM cell wall hydrolase autolysin	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
CMS3_k127_2848016_4	479434.Sthe_0669	6.772e-218	709.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS3_k127_2848016_59	1121406.JAEX01000022_gene1418	8.808e-16	91.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria,2M99W@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_7,TPR_8
CMS3_k127_2848016_52	317025.Tcr_1199	1.65e-27	115.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,460WD@72273|Thiotrichales	72273|Thiotrichales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_2848016_5	1144275.COCOR_04191	1.424e-212	691.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_2848016_41	1502724.FF80_02828	5.782e-47	193.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,3N6K5@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Prephenate dehydrogenase	tyrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS3_k127_2848016_21	1499967.BAYZ01000148_gene1750	2.174e-96	343.0	COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_2848016_17	1232410.KI421418_gene2304	6.625e-104	354.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,43SBV@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS3_k127_2848016_43	292459.STH851	1.341e-44	178.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS3_k127_2848016_27	243231.GSU2371	7.848e-68	257.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS3_k127_2848016_8	1238182.C882_1065	4.942e-169	551.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,2JPTN@204441|Rhodospirillales	204441|Rhodospirillales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2848016_49	1316927.ATKI01000054_gene595	1.187e-33	139.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1YN4J@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS3_k127_2848016_32	1232410.KI421415_gene3077	1.725e-65	246.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
CMS3_k127_2848016_22	264732.Moth_1340	2.573e-82	295.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS3_k127_2848016_25	1268622.AVS7_01644	4.39e-70	259.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,4A9SQ@80864|Comamonadaceae	28216|Betaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_2848016_9	1232410.KI421415_gene3080	7.579e-156	511.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43T7B@69541|Desulfuromonadales	28221|Deltaproteobacteria	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS3_k127_2848016_47	316067.Geob_1869	7.916e-41	174.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
CMS3_k127_2848016_58	869210.Marky_0920	7.458e-21	102.0	COG0664@1|root,COG0664@2|Bacteria,1WJXH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_2848016_56	317025.Tcr_1049	1.898e-23	111.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,4631I@72273|Thiotrichales	72273|Thiotrichales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_2848016_38	204669.Acid345_0180	8.179e-51	191.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
CMS3_k127_2848016_46	383372.Rcas_2223	1.348e-41	158.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,37741@32061|Chloroflexia	32061|Chloroflexia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS3_k127_2848016_45	479434.Sthe_3238	2.449e-42	175.0	COG0717@1|root,COG0717@2|Bacteria,2GBA2@200795|Chloroflexi,27Y8U@189775|Thermomicrobia	189775|Thermomicrobia	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS3_k127_2848016_48	1382304.JNIL01000001_gene3317	5.987e-38	162.0	COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,279TU@186823|Alicyclobacillaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_2848016_54	1128421.JAGA01000003_gene3229	3.463e-24	117.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,NodS,PIG-L
CMS3_k127_2848016_24	1128421.JAGA01000001_gene2365	5.433e-76	271.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS3_k127_2848016_12	1123073.KB899241_gene2212	7.671e-136	449.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1X3QG@135614|Xanthomonadales	135614|Xanthomonadales	G	COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
CMS3_k127_2848016_40	1333998.M2A_0448	6.823e-48	183.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,4BQ42@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF502)	MA20_12960	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS3_k127_2848016_63	1385515.N791_14480	1.562e-05	57.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1X6XU@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane protein, required for colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS3_k127_2848016_7	1254432.SCE1572_44220	1.971e-181	582.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,42PXZ@68525|delta/epsilon subdivisions,2X667@28221|Deltaproteobacteria,2Z33M@29|Myxococcales	28221|Deltaproteobacteria	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
CMS3_k127_2848016_19	1254432.SCE1572_44215	1.032e-97	343.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,42MXW@68525|delta/epsilon subdivisions,2WK94@28221|Deltaproteobacteria,2YWE8@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
CMS3_k127_2848016_37	1192034.CAP_3326	2.361e-53	193.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,43F3T@68525|delta/epsilon subdivisions,2X9UG@28221|Deltaproteobacteria,2YV6A@29|Myxococcales	28221|Deltaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	-	-	-	-	-	-	-	-	-	ChaC
CMS3_k127_2848016_39	1523503.JPMY01000003_gene4182	3.46e-49	198.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_2848016_2	1232683.ADIMK_1382	9.941e-239	746.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,464PE@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.71	ko:K00128,ko:K06447	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_2848016_51	1394178.AWOO02000073_gene2274	3.652e-28	131.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EGFA@85012|Streptosporangiales	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_2848016_28	1041522.MCOL_V220836	1.322e-67	246.0	COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria,2365Z@1762|Mycobacteriaceae	201174|Actinobacteria	CG	PFAM Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
CMS3_k127_2848016_16	1313172.YM304_24680	3.86e-110	371.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_2848016_55	439235.Dalk_4189	6.995e-24	115.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_2848016_60	316067.Geob_3795	1.231e-14	89.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_2
CMS3_k127_2890277_1	338966.Ppro_2411	4.29e-41	170.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,43T0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CMS3_k127_2890277_0	1242864.D187_006569	4.635e-80	285.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2YV0E@29|Myxococcales	28221|Deltaproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS3_k127_2890277_2	404589.Anae109_0709	6.414e-29	126.0	2E2XW@1|root,32XYS@2|Bacteria,1N3ID@1224|Proteobacteria,42UFM@68525|delta/epsilon subdivisions,2WQKF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2890277_4	1034943.BN1094_01408	1.33e-10	74.0	2EW8H@1|root,33PMC@2|Bacteria,1NT8K@1224|Proteobacteria,1SMJP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2890277_3	709986.Deima_3288	8.499e-17	87.0	COG1749@1|root,COG4085@1|root,COG1749@2|Bacteria,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
CMS3_k127_2936201_25	1121861.KB899946_gene3923	7.811e-08	63.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2JP8I@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CMS3_k127_2936201_7	765911.Thivi_2438	6.641e-93	329.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WWX7@135613|Chromatiales	135613|Chromatiales	U	Type II secretory pathway component ExeA	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
CMS3_k127_2936201_22	1033743.CAES01000056_gene4731	1.52e-30	141.0	COG5146@1|root,COG5146@2|Bacteria,1V2R2@1239|Firmicutes,4HG04@91061|Bacilli,26X2U@186822|Paenibacillaceae	91061|Bacilli	H	Fumble	coaW	-	2.7.1.33	ko:K09680	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumble
CMS3_k127_2936201_27	1238182.C882_2200	1.125e-05	58.0	COG3266@1|root,COG3266@2|Bacteria,1QVU2@1224|Proteobacteria,2TWJR@28211|Alphaproteobacteria,2JZ0V@204441|Rhodospirillales	204441|Rhodospirillales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2936201_13	266117.Rxyl_2532	1.863e-56	227.0	COG0614@1|root,COG0614@2|Bacteria,2GYJE@201174|Actinobacteria,4CTJ1@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
CMS3_k127_2936201_10	1444309.JAQG01000181_gene3547	1.209e-81	285.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,4HEZ1@91061|Bacilli,275P2@186822|Paenibacillaceae	91061|Bacilli	D	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CMS3_k127_2936201_11	929712.KI912613_gene4816	4.35e-70	252.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4CPDY@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CMS3_k127_2936201_3	383372.Rcas_3335	7.162e-179	576.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376IG@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3	ko:K01897,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2936201_1	1206741.BAFX01000197_gene3573	2.799e-217	689.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4FUZR@85025|Nocardiaceae	201174|Actinobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_2936201_14	1254432.SCE1572_31265	3.944e-53	212.0	COG3607@1|root,COG3607@2|Bacteria,1RH1T@1224|Proteobacteria,42UQI@68525|delta/epsilon subdivisions,2WQII@28221|Deltaproteobacteria,2YVBZ@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_2936201_2	1267535.KB906767_gene3396	9.056e-205	656.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS3_k127_2936201_23	1394178.AWOO02000071_gene381	4.294e-30	136.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
CMS3_k127_2936201_18	1380394.JADL01000012_gene838	3.39e-37	143.0	COG3795@1|root,COG3795@2|Bacteria,1N4SY@1224|Proteobacteria,2UBTF@28211|Alphaproteobacteria,2JX08@204441|Rhodospirillales	204441|Rhodospirillales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_2936201_5	1380394.JADL01000012_gene839	1.019e-152	507.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2TSNH@28211|Alphaproteobacteria,2JRN8@204441|Rhodospirillales	204441|Rhodospirillales	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_2936201_9	502025.Hoch_5960	6.836e-83	290.0	COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YUHG@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_2936201_24	1136417.AZWE01000024_gene668	3.749e-24	119.0	COG2931@1|root,COG2931@2|Bacteria,2IAYD@201174|Actinobacteria	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2936201_4	710421.Mycch_2953	5.637e-165	535.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2341M@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2936201_16	298654.FraEuI1c_3945	4.495e-46	170.0	COG0183@1|root,COG1545@1|root,COG0183@2|Bacteria,COG1545@2|Bacteria,2IETY@201174|Actinobacteria	201174|Actinobacteria	I	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_2936201_20	653045.Strvi_0987	6.754e-34	141.0	COG1309@1|root,COG1309@2|Bacteria,2GK0V@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2936201_15	258052.JNYV01000002_gene1574	7.787e-49	197.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,2M28J@2063|Kitasatospora	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K03366	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R02855,R02946,R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2936201_6	365528.KB891181_gene4717	2.493e-112	381.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_2936201_8	1282876.BAOK01000001_gene3043	5.608e-86	294.0	COG1028@1|root,COG1028@2|Bacteria,1R6PG@1224|Proteobacteria,2U54K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2936201_0	1306174.JODP01000007_gene2522	1.096e-229	730.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase, S9A B C family, catalytic domain protein	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_2936201_17	1184267.A11Q_652	4.088e-41	169.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,42WNA@68525|delta/epsilon subdivisions,2MT6U@213481|Bdellovibrionales,2WRKM@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Histidine kinase	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS3_k127_2936201_19	378806.STAUR_1187	1.104e-34	152.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,42ZS1@68525|delta/epsilon subdivisions,2WV25@28221|Deltaproteobacteria,2YVBN@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
CMS3_k127_2936201_26	1440774.Y900_014230	5.213e-07	61.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,2347Z@1762|Mycobacteriaceae	201174|Actinobacteria	K	response regulator	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_2936201_12	222534.KB893715_gene1716	1.912e-69	255.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2936201_21	331869.BAL199_03819	5.294e-31	125.0	COG0563@1|root,COG0563@2|Bacteria,1R4TI@1224|Proteobacteria,2TSIR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	adenylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
CMS3_k127_2948844_12	1442599.JAAN01000013_gene3662	7.308e-12	68.0	COG0563@1|root,COG0563@2|Bacteria,1R4TI@1224|Proteobacteria,1SQ0E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
CMS3_k127_2948844_10	926560.KE387023_gene2058	5.701e-22	108.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_2948844_14	584708.Apau_1766	2.539e-07	61.0	COG3860@1|root,COG3860@2|Bacteria,3TC9Y@508458|Synergistetes	508458|Synergistetes	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087
CMS3_k127_2948844_5	748247.AZKH_0648	4.487e-54	195.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,2VRAT@28216|Betaproteobacteria,2KWSB@206389|Rhodocyclales	206389|Rhodocyclales	L	G T U mismatch-specific DNA glycosylase	mug	-	-	-	-	-	-	-	-	-	-	-	UDG
CMS3_k127_2948844_3	156889.Mmc1_2110	2.662e-84	312.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria	1224|Proteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
CMS3_k127_2948844_2	1313172.YM304_41440	8.3e-102	345.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4CNYR@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_2948844_13	926692.AZYG01000012_gene875	2.842e-09	69.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_2948844_8	251229.Chro_2229	5.745e-42	172.0	COG1664@1|root,COG1664@2|Bacteria,1G2TI@1117|Cyanobacteria	1117|Cyanobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_2948844_7	204669.Acid345_1614	2.993e-44	185.0	COG5587@1|root,COG5587@2|Bacteria,3Y4D4@57723|Acidobacteria,2JJ1B@204432|Acidobacteriia	204432|Acidobacteriia	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
CMS3_k127_2948844_4	324602.Caur_1732	9.475e-70	249.0	COG1028@1|root,COG1028@2|Bacteria,2G8DK@200795|Chloroflexi,3776U@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2948844_6	1380386.JIAW01000012_gene1800	6.096e-47	196.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,23582@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2948844_0	502025.Hoch_2061	4.084e-190	615.0	COG3119@1|root,COG3119@2|Bacteria,1PG5D@1224|Proteobacteria,4358J@68525|delta/epsilon subdivisions,2WZJN@28221|Deltaproteobacteria,2Z29X@29|Myxococcales	28221|Deltaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2948844_9	110319.CF8_3025	4.266e-40	150.0	COG2329@1|root,COG2329@2|Bacteria,2IQWX@201174|Actinobacteria,4DVZ1@85009|Propionibacteriales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_2948844_1	1463825.JNXC01000006_gene2057	4.271e-114	386.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4E9EG@85010|Pseudonocardiales	201174|Actinobacteria	CG	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
CMS3_k127_2948844_11	391625.PPSIR1_02823	5.787e-18	86.0	COG2146@1|root,COG2146@2|Bacteria,1NWKP@1224|Proteobacteria	1224|Proteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_2961152_3	215803.DB30_8663	1.546e-34	138.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_2961152_0	1274374.CBLK010000086_gene4587	6.986e-85	293.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS3_k127_2961152_1	1144275.COCOR_03823	2.393e-51	198.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2961152_2	290397.Adeh_3633	1.095e-34	145.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
CMS3_k127_2961152_4	43354.JOIJ01000007_gene1639	5.531e-09	68.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
CMS3_k127_2993227_3	1282876.BAOK01000001_gene3291	2.25e-143	461.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,4BPI3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_2993227_4	765910.MARPU_03970	6.07e-137	447.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1WVX1@135613|Chromatiales	135613|Chromatiales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
CMS3_k127_2993227_1	1282876.BAOK01000001_gene3289	1.102e-157	509.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,4BP71@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
CMS3_k127_2993227_6	1244869.H261_00265	5.798e-125	407.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2JPQI@204441|Rhodospirillales	204441|Rhodospirillales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS3_k127_2993227_12	314345.SPV1_01782	9.766e-13	79.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
CMS3_k127_2993227_10	391600.ABRU01000050_gene139	5.69e-22	111.0	COG5031@1|root,COG5031@2|Bacteria,1RGXT@1224|Proteobacteria,2U8F1@28211|Alphaproteobacteria,2KGHQ@204458|Caulobacterales	204458|Caulobacterales	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	ko:K18586	-	-	-	-	ko00000	-	-	-	Coq4
CMS3_k127_2993227_8	998674.ATTE01000001_gene3160	1.082e-30	142.0	COG2815@1|root,COG2815@2|Bacteria	2|Bacteria	G	serine threonine protein kinase	spk1	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA
CMS3_k127_2993227_14	1340493.JNIF01000004_gene178	5.07e-07	64.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,Reprolysin_3
CMS3_k127_2993227_15	1123070.KB899261_gene2138	1.044e-06	60.0	295V5@1|root,2ZT65@2|Bacteria,46WNU@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2993227_13	378806.STAUR_7171	6.586e-12	75.0	28UXW@1|root,2ZH1P@2|Bacteria,1Q3E7@1224|Proteobacteria,43403@68525|delta/epsilon subdivisions,2X4CD@28221|Deltaproteobacteria,2YYR8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2993227_16	1234595.C725_2062	0.0005669	51.0	COG5126@1|root,COG5126@2|Bacteria,1N0UM@1224|Proteobacteria,2UCE3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_2993227_9	247634.GPB2148_989	1.127e-23	113.0	COG2050@1|root,COG2050@2|Bacteria,1NF9N@1224|Proteobacteria,1SIHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2993227_11	886293.Sinac_5019	2.946e-20	97.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_2993227_5	1192034.CAP_4238	1.924e-127	422.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria,2YYYG@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2993227_2	1192034.CAP_4237	1.749e-147	481.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,42ZRT@68525|delta/epsilon subdivisions,2WUTK@28221|Deltaproteobacteria,2YY3I@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2993227_7	448385.sce8943	1.112e-41	166.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,42UHJ@68525|delta/epsilon subdivisions,2WT4S@28221|Deltaproteobacteria,2YUXZ@29|Myxococcales	28221|Deltaproteobacteria	K	Arabinose-binding domain of AraC transcription regulator, N-term	oruR2	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
CMS3_k127_2993227_0	247633.GP2143_17546	8.201e-179	567.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,1RZPD@1236|Gammaproteobacteria,1J81Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	EHN
CMS3_k127_2993269_2	1123366.TH3_18794	1.682e-34	136.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,2JQB9@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_2993269_3	682795.AciX8_0551	4.267e-32	136.0	COG0704@1|root,COG0704@2|Bacteria,3Y4DI@57723|Acidobacteria,2JJ5M@204432|Acidobacteriia	204432|Acidobacteriia	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS3_k127_2993269_1	391625.PPSIR1_08142	4.513e-72	262.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YURD@29|Myxococcales	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2993269_0	443143.GM18_1480	1.09e-98	353.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
CMS3_k127_2993269_4	314230.DSM3645_05525	8.945e-17	88.0	COG1074@1|root,COG1074@2|Bacteria,2IX1B@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the helicase family. UvrD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_3008680_52	648885.KB316284_gene4647	8.544e-05	47.0	2DNZS@1|root,32ZYX@2|Bacteria,1QUTX@1224|Proteobacteria,2TYWT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
CMS3_k127_3008680_24	1245471.PCA10_23420	3.962e-58	223.0	COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,1S1R2@1236|Gammaproteobacteria,1YFM8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Methylamine dehydrogenase heavy chain (MADH)	mauB	-	1.4.9.1	ko:K15229	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_H
CMS3_k127_3008680_44	397278.JOJN01000007_gene3113	1.391e-24	119.0	COG0385@1|root,COG0385@2|Bacteria,2GMAM@201174|Actinobacteria,4DPZ6@85009|Propionibacteriales	201174|Actinobacteria	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS3_k127_3008680_19	656024.FsymDg_2042	3.964e-82	300.0	COG2141@1|root,COG2141@2|Bacteria,2ID60@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_3008680_18	402881.Plav_1367	2.053e-84	296.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2U0CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
CMS3_k127_3008680_26	1201290.M902_3272	2.819e-48	190.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,42UNJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_3008680_37	1537915.JU57_02225	5.396e-34	139.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,430KK@68525|delta/epsilon subdivisions,2YRZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the DsbB family	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
CMS3_k127_3008680_11	298654.FraEuI1c_3280	4.869e-117	391.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
CMS3_k127_3008680_12	1380347.JNII01000011_gene1028	3.452e-114	378.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4EUSJ@85013|Frankiales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3008680_35	402881.Plav_0477	8.228e-36	156.0	COG0824@1|root,COG0824@2|Bacteria,1R66P@1224|Proteobacteria,2U3KF@28211|Alphaproteobacteria,1JPG8@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS3_k127_3008680_32	1385514.N782_16030	6.044e-41	161.0	29VVU@1|root,30HDP@2|Bacteria,1V3S5@1239|Firmicutes,4HHWN@91061|Bacilli,2YAC4@289201|Pontibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_3008680_29	794903.OPIT5_24505	4.159e-43	173.0	COG0111@1|root,COG0111@2|Bacteria,46Y9B@74201|Verrucomicrobia,3K95U@414999|Opitutae	414999|Opitutae	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
CMS3_k127_3008680_4	1229780.BN381_40059	8.885e-185	622.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS3_k127_3008680_17	1125863.JAFN01000001_gene842	3.649e-85	291.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2WJR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	LysM,MS_channel,TM_helix
CMS3_k127_3008680_40	1026882.MAMP_02110	1.325e-32	140.0	COG3137@1|root,COG3137@2|Bacteria,1NUVP@1224|Proteobacteria,1SNDK@1236|Gammaproteobacteria,46293@72273|Thiotrichales	72273|Thiotrichales	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS3_k127_3008680_5	1205680.CAKO01000040_gene1084	9.319e-155	505.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,2JRI5@204441|Rhodospirillales	204441|Rhodospirillales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
CMS3_k127_3008680_28	1122132.AQYH01000008_gene2489	1.04e-43	165.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,4BCDV@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0178 family	MA20_27470	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
CMS3_k127_3008680_0	1123073.KB899241_gene2226	1.372e-301	946.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales	135614|Xanthomonadales	I	converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
CMS3_k127_3008680_21	269796.Rru_A0974	2.819e-74	267.0	COG1659@1|root,COG1659@2|Bacteria,1QKHQ@1224|Proteobacteria,2TUWD@28211|Alphaproteobacteria,2JR8W@204441|Rhodospirillales	204441|Rhodospirillales	S	Encapsulating protein for peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Linocin_M18
CMS3_k127_3008680_41	710111.FraQA3DRAFT_0404	1.722e-31	137.0	COG3461@1|root,COG3461@2|Bacteria,2GZN9@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_3008680_50	1131269.AQVV01000032_gene310	1.066e-09	70.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS3_k127_3008680_48	1177154.Y5S_03155	1.331e-10	68.0	2E7TI@1|root,3328N@2|Bacteria,1NCCK@1224|Proteobacteria,1SDE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
CMS3_k127_3008680_51	1177181.T9A_00786	3.641e-05	51.0	2E7TI@1|root,3328N@2|Bacteria,1NCCK@1224|Proteobacteria,1SDE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
CMS3_k127_3008680_6	1205680.CAKO01000002_gene2127	9.275e-138	454.0	COG2141@1|root,COG2141@2|Bacteria,1MUTJ@1224|Proteobacteria,2TTZI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_3008680_45	485918.Cpin_5772	1.641e-20	96.0	COG2259@1|root,31BQE@2|Bacteria,4NQH2@976|Bacteroidetes,1ITDX@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS3_k127_3008680_10	710685.MycrhN_6217	1.634e-117	409.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,234BA@1762|Mycobacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_3008680_30	880073.Calab_3098	5.118e-43	169.0	COG2755@1|root,COG2755@2|Bacteria,2NQ5Y@2323|unclassified Bacteria	2|Bacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	Lipase_GDSL_2
CMS3_k127_3008680_16	1173026.Glo7428_1576	7.03e-87	313.0	COG0451@1|root,COG0451@2|Bacteria,1GC7G@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_3008680_20	1231392.OCGS_0957	8.965e-78	270.0	COG0500@1|root,COG2226@2|Bacteria,1R439@1224|Proteobacteria,2U0N2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_3008680_36	1249627.D779_0738	1.208e-34	153.0	COG1404@1|root,COG1404@2|Bacteria,1RC5K@1224|Proteobacteria,1S3I9@1236|Gammaproteobacteria,1WXY7@135613|Chromatiales	135613|Chromatiales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_3008680_47	529818.AMSG_10016T0	8.006e-12	79.0	KOG3607@1|root,KOG3607@2759|Eukaryota	2759|Eukaryota	L	metalloendopeptidase activity	KMT2D	-	2.1.1.43,2.7.11.1	ko:K06261,ko:K08867,ko:K09187,ko:K14972,ko:K20371	ko00310,ko04512,ko04611,ko04640,ko04934,map00310,map04512,map04611,map04640,map04934	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko01001,ko01009,ko03000,ko03036,ko04090,ko04131	-	-	-	DC_STAMP,FYRC,FYRN,Laminin_G_3,PHD,Reprolysin_3,Reprolysin_4,SET,SH3_1,SH3_9,TSP_1,zf-HC5HC2H
CMS3_k127_3008680_25	247634.GPB2148_889	7.649e-56	214.0	2EACJ@1|root,334GH@2|Bacteria	2|Bacteria	S	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	LEH,SnoaL_2
CMS3_k127_3008680_31	246196.MSMEI_6492	1.608e-41	169.0	COG1524@1|root,COG1524@2|Bacteria,2HSIU@201174|Actinobacteria,23CG7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_3008680_1	402881.Plav_2593	1.959e-221	707.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,1JPPK@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
CMS3_k127_3008680_8	1313172.YM304_03040	9.722e-125	414.0	COG4638@1|root,COG4638@2|Bacteria,2I3Q1@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Rieske 2Fe-2S domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_3008680_3	314230.DSM3645_07745	9.835e-208	669.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS3_k127_3008680_15	1148.1651696	1.689e-93	336.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1H4VX@1142|Synechocystis	1117|Cyanobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS3_k127_3008680_34	1288826.MSNKSG1_01663	3.235e-39	150.0	COG2329@1|root,COG2329@2|Bacteria,1RJMH@1224|Proteobacteria,1SAYM@1236|Gammaproteobacteria,4687E@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_3008680_7	402881.Plav_1126	3.299e-128	419.0	COG0625@1|root,COG0625@2|Bacteria,1Q9ND@1224|Proteobacteria,2TT22@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
CMS3_k127_3008680_9	765910.MARPU_09300	5.959e-119	404.0	COG0477@1|root,COG2814@2|Bacteria,1MX4G@1224|Proteobacteria,1RMEF@1236|Gammaproteobacteria,1X0BV@135613|Chromatiales	135613|Chromatiales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_3008680_39	867845.KI911784_gene2765	8.657e-33	146.0	COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2G7PG@200795|Chloroflexi,3763G@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS3_k127_3008680_46	1116232.AHBF01000118_gene4343	4.62e-19	94.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7
CMS3_k127_3008680_43	1123072.AUDH01000001_gene2761	9.824e-25	113.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3008680_22	1459636.NTE_02662	8.736e-74	270.0	COG0175@1|root,arCOG00124@2157|Archaea,41S9Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS3_k127_3008680_42	867903.ThesuDRAFT_02037	1.979e-26	111.0	COG0011@1|root,COG0011@2|Bacteria,1VAIR@1239|Firmicutes,24NBA@186801|Clostridia	186801|Clostridia	S	TIGRFAM Protein of	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
CMS3_k127_3008680_33	751945.Theos_2027	1.505e-39	154.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS3_k127_3008680_14	1123070.KB899254_gene1284	1.005e-99	349.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS3_k127_3008680_23	1121033.AUCF01000010_gene4394	7.695e-70	266.0	COG0318@1|root,COG0318@2|Bacteria,1QXPD@1224|Proteobacteria,2TZJQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
CMS3_k127_3008680_38	1123405.AUMM01000009_gene1165	1.314e-33	151.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
CMS3_k127_3008680_27	362242.MUL_0819	6.049e-46	180.0	COG0300@1|root,COG1063@1|root,COG0300@2|Bacteria,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3008680_2	402881.Plav_3137	1.735e-214	702.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,2TV04@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3008680_13	926550.CLDAP_32030	6.694e-103	350.0	COG0673@1|root,COG0673@2|Bacteria,2G7RI@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_3008680_49	589865.DaAHT2_0817	1.04e-09	65.0	COG0457@1|root,COG0457@2|Bacteria,1N0Q1@1224|Proteobacteria,42TBT@68525|delta/epsilon subdivisions,2WQ96@28221|Deltaproteobacteria,2MK73@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_3045264_5	1304275.C41B8_18186	3.584e-48	175.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1SYHR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin
CMS3_k127_3045264_7	756272.Plabr_1849	1.657e-19	100.0	COG5126@1|root,COG5126@2|Bacteria	2|Bacteria	DTZ	Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_3045264_1	1229780.BN381_360022	1.488e-89	308.0	COG1680@1|root,COG1680@2|Bacteria,2HEWU@201174|Actinobacteria,3UXIA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_3045264_9	880072.Desac_2865	5.731e-06	58.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2MRY9@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS3_k127_3045264_0	59538.XP_005968778.1	1.094e-169	539.0	COG1062@1|root,KOG0022@2759|Eukaryota,397PJ@33154|Opisthokonta,3BIQH@33208|Metazoa,3CYWE@33213|Bilateria,4871P@7711|Chordata,491PB@7742|Vertebrata,3J1Y5@40674|Mammalia	2759|Eukaryota	Q	alcohol dehydrogenase (NAD) activity	ADH1	GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121,ko:K02267,ko:K13980,ko:K18857	ko00010,ko00071,ko00190,ko00350,ko00592,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,ko05204,map00010,map00071,map00190,map00350,map00592,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map04260,map04714,map04932,map05010,map05012,map05016,map05204	M00154	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310,R10783	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	3.D.4.11,3.D.4.8	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3045264_3	547163.BN979_00160	8.495e-57	221.0	COG1335@1|root,COG1335@2|Bacteria,2I81Y@201174|Actinobacteria,2355H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS3_k127_3045264_4	1123320.KB889669_gene3266	3.349e-53	192.0	2DBEE@1|root,2Z8S9@2|Bacteria,2ISRT@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_3045264_6	478741.JAFS01000001_gene2028	7.149e-33	140.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_3045264_8	1449076.JOOE01000003_gene3465	9.416e-07	62.0	COG3279@1|root,COG3279@2|Bacteria,1NWIR@1224|Proteobacteria	1224|Proteobacteria	KT	LytTr DNA-binding domain	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
CMS3_k127_3045264_2	765911.Thivi_1620	9.629e-75	278.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1X1Z5@135613|Chromatiales	135613|Chromatiales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS3_k127_3072250_19	1047013.AQSP01000106_gene1773	2.694e-44	187.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS3_k127_3072250_29	251229.Chro_4936	1.264e-08	68.0	2AQRE@1|root,31FZ6@2|Bacteria,1G7D6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3072250_24	1124780.ANNU01000048_gene2123	9.792e-32	128.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,47S1E@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
CMS3_k127_3072250_23	1304275.C41B8_09993	4.474e-33	136.0	COG0546@1|root,COG0546@2|Bacteria,1N0R4@1224|Proteobacteria,1SIP8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS3_k127_3072250_25	1304275.C41B8_09973	2.804e-18	100.0	2DVWA@1|root,33XFW@2|Bacteria,1RDKB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3072250_11	1304275.C41B8_09998	6.431e-75	277.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Acylneuraminate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
CMS3_k127_3072250_8	1304275.C41B8_09983	4.261e-93	338.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_3072250_9	1288494.EBAPG3_28540	1.6e-88	331.0	COG0438@1|root,COG0438@2|Bacteria,1RBQV@1224|Proteobacteria,2W3QE@28216|Betaproteobacteria,371TA@32003|Nitrosomonadales	28216|Betaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3072250_12	570952.ATVH01000011_gene200	1.978e-68	242.0	2DG8R@1|root,2ZUYV@2|Bacteria,1R8VA@1224|Proteobacteria,2VGKJ@28211|Alphaproteobacteria,2JZ9B@204441|Rhodospirillales	204441|Rhodospirillales	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_3072250_2	1410626.JHXB01000021_gene1473	4.775e-178	584.0	COG0662@1|root,COG2089@1|root,COG0662@2|Bacteria,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,27K4Z@186928|unclassified Lachnospiraceae	186801|Clostridia	M	SAF	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,NeuB
CMS3_k127_3072250_4	314278.NB231_04135	1.134e-154	522.0	COG3660@1|root,COG3660@2|Bacteria,1R70U@1224|Proteobacteria,1S0W8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
CMS3_k127_3072250_10	314278.NB231_04140	3.126e-79	293.0	2DG8R@1|root,2ZUYV@2|Bacteria,1R8VA@1224|Proteobacteria,1T0PJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_3072250_17	362242.MUL_2390	2.704e-57	224.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	MA20_16915	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_3,Glyoxalase_4
CMS3_k127_3072250_13	485913.Krac_11003	2.447e-68	249.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS3_k127_3072250_1	443143.GM18_4219	2.064e-195	622.0	COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,42QIB@68525|delta/epsilon subdivisions,2WKXI@28221|Deltaproteobacteria,43SDB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapB	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_3072250_27	404589.Anae109_2590	2.04e-16	89.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_2590|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3072250_15	479434.Sthe_2745	1.925e-60	216.0	COG1611@1|root,COG1611@2|Bacteria,2G6IB@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS3_k127_3072250_0	1125863.JAFN01000001_gene1462	0.0	1017.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
CMS3_k127_3072250_16	290315.Clim_1983	3.926e-58	211.0	COG2010@1|root,COG2010@2|Bacteria,1FEAI@1090|Chlorobi	1090|Chlorobi	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CMS3_k127_3072250_26	562970.Btus_2226	6.503e-17	90.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,278K5@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3072250_28	555088.DealDRAFT_1190	8.75e-13	79.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_3072250_21	1232410.KI421415_gene3120	1.833e-36	152.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,43SJ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS3_k127_3072250_18	502025.Hoch_2213	3.55e-45	175.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,43AJU@68525|delta/epsilon subdivisions,2X600@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,MerR_1
CMS3_k127_3072250_7	1218076.BAYB01000008_gene1665	3.2e-113	377.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,1K0NV@119060|Burkholderiaceae	28216|Betaproteobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS3_k127_3072250_6	887062.HGR_05449	5.235e-133	452.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
CMS3_k127_3072250_14	330214.NIDE0211	2.148e-66	254.0	COG3496@1|root,COG3496@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1365)	-	-	2.1.1.79	ko:K00574,ko:K09701	-	-	-	-	ko00000,ko01000	-	-	-	DUF1365
CMS3_k127_3072250_5	338966.Ppro_0127	2.36e-137	464.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WKGA@28221|Deltaproteobacteria,43TGT@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS,DUF1365
CMS3_k127_3072250_20	404589.Anae109_0807	3.257e-40	156.0	COG4276@1|root,COG4276@2|Bacteria,1N6EC@1224|Proteobacteria,42U3N@68525|delta/epsilon subdivisions,2WQTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS3_k127_3072250_22	502025.Hoch_5691	6.382e-34	141.0	COG3011@1|root,COG3011@2|Bacteria,1PV31@1224|Proteobacteria,42WAC@68525|delta/epsilon subdivisions,2WSCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS3_k127_3072250_3	1283284.AZUK01000001_gene2736	8.568e-166	534.0	COG1486@1|root,COG1486@2|Bacteria,1NI6G@1224|Proteobacteria,1RN45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS3_k127_3114703_5	525909.Afer_1768	4.845e-118	394.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CMU2@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_3114703_19	1125863.JAFN01000001_gene2043	4.214e-21	104.0	COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,42RW8@68525|delta/epsilon subdivisions,2WNP6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
CMS3_k127_3114703_28	485913.Krac_9732	0.0005751	51.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
CMS3_k127_3114703_21	382464.ABSI01000010_gene3594	3.357e-17	90.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,2IUFS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3114703_27	1444309.JAQG01000029_gene2553	7.936e-06	57.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,4HCWZ@91061|Bacilli,26R9C@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the ParA family	ylxH	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
CMS3_k127_3114703_13	1142394.PSMK_30020	7.74e-54	207.0	COG1192@1|root,COG3170@1|root,COG1192@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496,ko:K09000	-	-	-	-	ko00000,ko02048,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_3114703_22	1463821.JOGR01000004_gene2407	3.738e-15	83.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4EYNM@85014|Glycomycetales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_3114703_12	868864.Dester_0088	3.255e-54	209.0	COG2074@1|root,COG2074@2|Bacteria,2G4F4@200783|Aquificae	200783|Aquificae	G	ATP cone domain	-	-	-	ko:K05715	-	-	R02664	RC00002,RC00017	ko00000,ko01000	-	-	-	ATP-cone
CMS3_k127_3114703_2	479434.Sthe_3485	1.357e-168	542.0	COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_3114703_10	479434.Sthe_3486	1.181e-78	283.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3114703_11	635013.TherJR_0820	4.025e-71	265.0	COG1807@1|root,COG1807@2|Bacteria,1TTJ7@1239|Firmicutes,24ZXI@186801|Clostridia	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	-
CMS3_k127_3114703_24	439235.Dalk_4189	5.463e-13	81.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_3114703_17	68570.DC74_3991	3.37e-30	129.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS3_k127_3114703_8	243231.GSU1111	1.809e-87	301.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,43STZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_3114703_3	572544.Ilyop_0804	3.48e-150	491.0	COG1696@1|root,COG1696@2|Bacteria,3796N@32066|Fusobacteria	32066|Fusobacteria	M	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_3114703_26	1287488.HMPREF0671_09645	9.663e-12	79.0	COG2755@1|root,COG2755@2|Bacteria,4NSWA@976|Bacteroidetes,2FUHI@200643|Bacteroidia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3114703_1	1123256.KB907928_gene2095	2.958e-169	559.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1X4FN@135614|Xanthomonadales	135614|Xanthomonadales	G	Glucose dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
CMS3_k127_3114703_16	56780.SYN_00526	6.287e-41	160.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2MRTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
CMS3_k127_3114703_0	472759.Nhal_0363	4.016e-189	619.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1X28I@135613|Chromatiales	135613|Chromatiales	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS3_k127_3114703_4	1278073.MYSTI_05340	4.55e-145	475.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2YUHB@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS3_k127_3114703_20	639283.Snov_0365	5.219e-19	91.0	COG4770@1|root,COG4770@2|Bacteria,1NJ80@1224|Proteobacteria,2UKHH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
CMS3_k127_3114703_25	1246474.ANBE01000014_gene2784	7.028e-12	79.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4EFMK@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
CMS3_k127_3114703_9	113395.AXAI01000023_gene7183	3.582e-83	286.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TUHP@28211|Alphaproteobacteria,3JRVY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_35605	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3114703_6	290397.Adeh_1289	1.231e-103	370.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2Z2SY@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_3114703_14	631362.Thi970DRAFT_01284	5.207e-48	175.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1WYNT@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
CMS3_k127_3114703_7	344747.PM8797T_20034	4.326e-90	336.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS3_k127_3114703_23	1382306.JNIM01000001_gene1642	5.589e-14	85.0	COG1051@1|root,COG1051@2|Bacteria,2G8SP@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_3114703_18	502025.Hoch_4188	7.186e-27	122.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_3114703_15	479434.Sthe_1410	3.289e-46	177.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi,27Y6D@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS3_k127_3185696_16	1123392.AQWL01000005_gene2887	3.435e-07	64.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,1KRIB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_3185696_2	671143.DAMO_2859	7.689e-189	602.0	COG0312@1|root,COG0312@2|Bacteria,2NNWH@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_3185696_8	443143.GM18_1204	2.062e-52	210.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria,43TG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
CMS3_k127_3185696_15	1125863.JAFN01000001_gene2024	1.406e-10	75.0	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WSE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
CMS3_k127_3185696_9	1242864.D187_003773	1.346e-41	173.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
CMS3_k127_3185696_12	1121918.ARWE01000001_gene730	4.597e-21	109.0	COG3156@1|root,COG3156@2|Bacteria,1PQN0@1224|Proteobacteria,4378V@68525|delta/epsilon subdivisions,2X2BY@28221|Deltaproteobacteria,43UCS@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
CMS3_k127_3185696_17	1278073.MYSTI_02890	5.157e-07	63.0	COG4970@1|root,COG4970@2|Bacteria,1NKTQ@1224|Proteobacteria,42X2U@68525|delta/epsilon subdivisions,2WSTU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein J	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CMS3_k127_3185696_18	1045855.DSC_02700	4.851e-05	54.0	COG4970@1|root,COG4970@2|Bacteria,1NA3K@1224|Proteobacteria,1T08R@1236|Gammaproteobacteria,1XCZB@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type II transport protein GspH	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CMS3_k127_3185696_11	1479238.JQMZ01000001_gene269	3.093e-36	146.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U7GY@28211|Alphaproteobacteria,440MT@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NU	Type II secretion system (T2SS), protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_3185696_6	404589.Anae109_0728	6.378e-107	360.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CMS3_k127_3185696_3	290397.Adeh_0685	2.826e-169	591.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS3_k127_3185696_5	1232410.KI421418_gene2158	1.942e-123	427.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,43UC5@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Bacterial type II/III secretion system short domain	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_3185696_14	1121405.dsmv_0459	4.4e-12	77.0	COG3031@1|root,COG3031@2|Bacteria,1PUWN@1224|Proteobacteria,42T73@68525|delta/epsilon subdivisions,2WPQU@28221|Deltaproteobacteria,2MK5Q@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CMS3_k127_3185696_0	644282.Deba_0170	1.446e-266	840.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_3185696_13	383372.Rcas_2558	6.183e-15	83.0	COG0071@1|root,COG0071@2|Bacteria,2GBQD@200795|Chloroflexi,37615@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS3_k127_3185696_1	469383.Cwoe_5273	1.201e-253	809.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPC3@84995|Rubrobacteria	84995|Rubrobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_3185696_10	1125863.JAFN01000001_gene972	9.388e-39	158.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS3_k127_3185696_7	883.DvMF_2801	2.009e-88	318.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions,2WK7W@28221|Deltaproteobacteria,2M8T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	pfam mofrl	Glyctk	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS3_k127_3185696_4	945543.VIBR0546_17713	3.225e-138	455.0	COG1524@1|root,COG1524@2|Bacteria,1NRIA@1224|Proteobacteria,1SKE2@1236|Gammaproteobacteria,1XVP3@135623|Vibrionales	135623|Vibrionales	S	Type I phosphodiesterase / nucleotide pyrophosphatase	VVA1274	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_3297957_3	3218.PP1S46_300V6.1	3.912e-69	254.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_3297957_2	526225.Gobs_0246	1.125e-98	335.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,4ETYM@85013|Frankiales	201174|Actinobacteria	IQ	KR domain	rhlG	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS3_k127_3297957_1	1123242.JH636434_gene4996	2.693e-109	375.0	COG1432@1|root,COG1432@2|Bacteria,2IY4C@203682|Planctomycetes	203682|Planctomycetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS3_k127_3297957_4	290397.Adeh_0969	6.273e-45	185.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,2Z0S2@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
CMS3_k127_3297957_0	448385.sce6205	6.225e-186	596.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria,2YUFY@29|Myxococcales	28221|Deltaproteobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529,ko:K13530	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
CMS3_k127_3297957_6	1168065.DOK_16543	1.389e-32	132.0	COG3686@1|root,COG3686@2|Bacteria,1N5MS@1224|Proteobacteria,1SBPS@1236|Gammaproteobacteria,1JAZ9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS3_k127_3297957_7	1169161.KB897729_gene1360	2.095e-26	119.0	COG0500@1|root,COG0500@2|Bacteria,2I8Y2@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_3297957_5	1415780.JPOG01000001_gene2510	1.701e-41	162.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1X5V2@135614|Xanthomonadales	135614|Xanthomonadales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS3_k127_3314843_13	1343740.M271_44330	2.33e-36	152.0	2EWES@1|root,33PT7@2|Bacteria,2IF44@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3314843_9	930169.B5T_02469	1.119e-93	318.0	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,1SMC5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3314843_1	1449353.JQMQ01000005_gene5520	1.1e-144	473.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,2NEQU@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.15	ko:K07544	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS3_k127_3314843_4	1449353.JQMQ01000005_gene5520	1.508e-134	445.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,2NEQU@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.15	ko:K07544	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS3_k127_3314843_2	479433.Caci_5356	4.882e-140	460.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3314843_7	502025.Hoch_5169	1.204e-113	377.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
CMS3_k127_3314843_14	1123367.C666_03650	2.231e-11	77.0	COG3000@1|root,COG3000@2|Bacteria,1N39U@1224|Proteobacteria,2VWC0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_3314843_0	1123320.KB889585_gene1895	1.472e-183	599.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3314843_3	1123320.KB889585_gene1894	1.153e-137	471.0	COG1804@1|root,COG1804@2|Bacteria,2IEU2@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_3314843_11	479433.Caci_5358	1.676e-68	237.0	COG2030@1|root,COG2030@2|Bacteria,2ICZR@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
CMS3_k127_3314843_12	479433.Caci_5359	3.837e-60	234.0	COG2030@1|root,COG2030@2|Bacteria,2IPFP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_3314843_5	1123320.KB889585_gene1891	1.681e-129	434.0	COG1960@1|root,COG1960@2|Bacteria,2I8MN@201174|Actinobacteria	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_3314843_10	1121382.JQKG01000007_gene3634	4.183e-73	273.0	COG1129@1|root,COG1129@2|Bacteria,1WJQQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
CMS3_k127_3314843_6	649638.Trad_1248	1.696e-118	404.0	COG4214@1|root,COG4214@2|Bacteria,1WI4P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
CMS3_k127_3314843_8	649638.Trad_1249	1.338e-104	344.0	COG4213@1|root,COG4213@2|Bacteria,1WIUJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ABC transporter substrate-binding protein	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
CMS3_k127_3334523_12	765420.OSCT_1048	4.457e-17	89.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi,37792@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_3334523_2	748449.Halha_1645	9.209e-148	490.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WA9C@53433|Halanaerobiales	186801|Clostridia	C	PFAM Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
CMS3_k127_3334523_14	1232410.KI421421_gene3696	5.165e-07	60.0	COG0745@1|root,COG0745@2|Bacteria,1QZ5N@1224|Proteobacteria,4307W@68525|delta/epsilon subdivisions,2X7RC@28221|Deltaproteobacteria,43UV3@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
CMS3_k127_3334523_8	235909.GK2665	1.227e-46	176.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1WF41@129337|Geobacillus	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS3_k127_3334523_4	468556.AQYG01000048_gene557	4.271e-87	294.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4GANI@85026|Gordoniaceae	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS3_k127_3334523_9	1382359.JIAL01000001_gene480	2.95e-46	178.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
CMS3_k127_3334523_3	502025.Hoch_6344	5.488e-105	353.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2YXJE@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_3334523_10	521045.Kole_1017	1.611e-38	160.0	COG0642@1|root,COG2205@2|Bacteria	521045.Kole_1017|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3334523_13	1382303.JPOM01000001_gene303	2.106e-14	78.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,2KGPE@204458|Caulobacterales	204458|Caulobacterales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS3_k127_3334523_11	1121405.dsmv_3287	7.656e-22	96.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	CP_0026	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
CMS3_k127_3334523_5	316274.Haur_4217	8.586e-82	297.0	COG2239@1|root,COG2239@2|Bacteria,2G6H7@200795|Chloroflexi,376RI@32061|Chloroflexia	32061|Chloroflexia	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_3334523_6	1192034.CAP_6386	2.539e-77	281.0	COG0625@1|root,COG0625@2|Bacteria,1R7YC@1224|Proteobacteria	1224|Proteobacteria	O	COG0695 glutaredoxin and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
CMS3_k127_3334523_0	653948.CCA16476	7.877e-253	809.0	COG0265@1|root,KOG1421@2759|Eukaryota	2759|Eukaryota	O	serine-type endopeptidase activity	NMA111	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006508,GO:0006629,GO:0006807,GO:0006915,GO:0006950,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009642,GO:0009644,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0012501,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0033554,GO:0034605,GO:0042548,GO:0043155,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051603,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_1,PDZ_2,Trypsin_2
CMS3_k127_3334523_7	68170.KL590492_gene6171	2.147e-53	199.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4E2BN@85010|Pseudonocardiales	201174|Actinobacteria	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS3_k127_3334523_1	326427.Cagg_1836	5.352e-190	602.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3456987_7	1156937.MFUM_270003	1.515e-88	308.0	COG0161@1|root,COG0161@2|Bacteria,46Z8A@74201|Verrucomicrobia,37GKM@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS3_k127_3456987_17	1313172.YM304_03860	1.634e-50	192.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
CMS3_k127_3456987_15	402881.Plav_3335	2.393e-54	205.0	COG0491@1|root,COG0491@2|Bacteria,1N3G4@1224|Proteobacteria,2UCQ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_3456987_20	596152.DesU5LDRAFT_2631	4.97e-27	128.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_3456987_5	262316.MAP_1979	1.529e-114	382.0	COG2124@1|root,COG2124@2|Bacteria,2HSPE@201174|Actinobacteria,2353U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_3456987_21	1211815.CBYP010000067_gene174	1.849e-11	66.0	COG1141@1|root,COG1141@2|Bacteria,2GWHY@201174|Actinobacteria,4EWP3@85013|Frankiales	201174|Actinobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CMS3_k127_3456987_12	588932.JHOF01000018_gene1339	1.699e-61	231.0	COG1524@1|root,COG1524@2|Bacteria,1N5SF@1224|Proteobacteria,2TU7V@28211|Alphaproteobacteria,2KG77@204458|Caulobacterales	204458|Caulobacterales	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_3456987_24	596153.Alide_3613	0.000129	55.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria,4AGT7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3456987_14	1454004.AW11_01052	2.294e-57	225.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2VNFS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,Fer4_7,FlpD
CMS3_k127_3456987_19	1382356.JQMP01000001_gene797	1.205e-27	118.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
CMS3_k127_3456987_13	1244869.H261_01552	2.806e-59	211.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2UJSY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome c oxidase (Subunit II)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3456987_1	608538.HTH_0153	2.551e-198	634.0	COG0843@1|root,COG0843@2|Bacteria	2|Bacteria	C	heme-copper terminal oxidase activity	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS3_k127_3456987_22	1104324.P186_0737	5.216e-08	64.0	COG1999@1|root,arCOG00313@2157|Archaea	2157|Archaea	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_3456987_0	886377.Murru_2669	4.173e-200	633.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,4NEXP@976|Bacteroidetes,1HXBK@117743|Flavobacteriia	976|Bacteroidetes	C	Nitrite reductase	nirK	-	1.7.2.1	ko:K00368,ko:K00405	ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020	M00156,M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3
CMS3_k127_3456987_11	1008457.BAEX01000015_gene1739	3.64e-68	258.0	COG1262@1|root,COG1262@2|Bacteria,4NGBN@976|Bacteroidetes,1HYTH@117743|Flavobacteriia,47HK6@76831|Myroides	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_3456987_18	861299.J421_0404	2.188e-30	138.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_3456987_16	1205680.CAKO01000030_gene4841	2.012e-53	204.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2U1CT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_3456987_8	1278073.MYSTI_04824	6.688e-87	301.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,437H0@68525|delta/epsilon subdivisions,2X2QC@28221|Deltaproteobacteria,2YXMK@29|Myxococcales	28221|Deltaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_3456987_9	1278073.MYSTI_04824	1.016e-86	326.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,437H0@68525|delta/epsilon subdivisions,2X2QC@28221|Deltaproteobacteria,2YXMK@29|Myxococcales	28221|Deltaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_3456987_23	1123242.JH636438_gene5778	5.456e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3456987_6	329726.AM1_2079	3.358e-112	369.0	COG1173@1|root,COG1173@2|Bacteria,1G0CD@1117|Cyanobacteria	1117|Cyanobacteria	P	'ABC-type dipeptide oligopeptide nickel transport	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS3_k127_3456987_4	329726.AM1_2080	1.468e-114	406.0	COG0601@1|root,COG0601@2|Bacteria,1G01A@1117|Cyanobacteria	1117|Cyanobacteria	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033,ko:K15581,ko:K15585	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS3_k127_3456987_2	329726.AM1_2081	9.004e-176	582.0	COG4166@1|root,COG4166@2|Bacteria,1GR16@1117|Cyanobacteria	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_3456987_3	1235279.C772_02598	5.797e-120	403.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,26D3I@186818|Planococcaceae	91061|Bacilli	E	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_3456987_10	1121405.dsmv_3561	2.14e-72	248.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,43BKT@68525|delta/epsilon subdivisions,2X6YX@28221|Deltaproteobacteria,2MJ3T@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13892,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00348,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
CMS3_k127_3487899_2	402881.Plav_1539	7.681e-98	328.0	COG0346@1|root,COG0346@2|Bacteria,1PNKN@1224|Proteobacteria,2V9TG@28211|Alphaproteobacteria,1JQJD@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_3487899_1	207954.MED92_14528	1.189e-99	344.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1XHXA@135619|Oceanospirillales	135619|Oceanospirillales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS3_k127_3487899_9	1282876.BAOK01000001_gene1826	4.59e-37	149.0	COG1309@1|root,COG1309@2|Bacteria,1MY6Y@1224|Proteobacteria,2UKSE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3487899_0	1282876.BAOK01000001_gene1087	5.031e-122	403.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,2TW6K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_3487899_11	391625.PPSIR1_19974	2.39e-25	111.0	COG3070@1|root,COG3070@2|Bacteria,1QEQQ@1224|Proteobacteria,4318J@68525|delta/epsilon subdivisions,2WWGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS3_k127_3487899_3	1397528.Q671_12760	6.845e-94	318.0	COG0500@1|root,COG2226@2|Bacteria,1N5DK@1224|Proteobacteria,1S3D8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS3_k127_3487899_8	1120950.KB892799_gene2145	9.47e-46	191.0	COG3119@1|root,COG3119@2|Bacteria,2IEA2@201174|Actinobacteria,4DWI5@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3487899_5	234267.Acid_6183	3.985e-59	224.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3487899_10	247634.GPB2148_2826	1.421e-30	137.0	COG4405@1|root,COG4405@2|Bacteria,1QXXX@1224|Proteobacteria,1S7NI@1236|Gammaproteobacteria,1J6DY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_3487899_4	1229780.BN381_360021	1.492e-91	315.0	COG1073@1|root,COG1073@2|Bacteria,2I8SP@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3487899_7	1041522.MCOL_V204900	5.756e-51	193.0	COG1028@1|root,COG1028@2|Bacteria	1041522.MCOL_V204900|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3487899_12	269799.Gmet_0146	1.424e-21	102.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,42V3W@68525|delta/epsilon subdivisions,2WREM@28221|Deltaproteobacteria,43SRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
CMS3_k127_3487899_6	326427.Cagg_0581	5.009e-56	213.0	COG0061@1|root,COG0061@2|Bacteria,2G8JA@200795|Chloroflexi,377AE@32061|Chloroflexia	32061|Chloroflexia	G	ATP-NAD kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
CMS3_k127_3487899_13	575540.Isop_1097	3.222e-09	66.0	COG1266@1|root,COG1266@2|Bacteria,2J0YI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_3515521_13	285514.JNWO01000008_gene2676	4.156e-05	46.0	COG0583@1|root,COG0583@2|Bacteria,2GNTF@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_3515521_1	1282876.BAOK01000001_gene1747	1.755e-74	262.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,2TWIW@28211|Alphaproteobacteria,4BTDE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_3515521_11	153948.NAL212_0192	1.472e-19	98.0	COG5549@1|root,COG5549@2|Bacteria,1PE84@1224|Proteobacteria,2WC16@28216|Betaproteobacteria,37458@32003|Nitrosomonadales	28216|Betaproteobacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3515521_14	1163407.UU7_06293	0.0001515	55.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
CMS3_k127_3515521_5	246197.MXAN_5907	5.682e-59	232.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CMS3_k127_3515521_8	331869.BAL199_15688	2.068e-28	132.0	COG0500@1|root,COG2226@2|Bacteria,1NIXW@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS3_k127_3515521_4	1244869.H261_05859	8.605e-65	241.0	COG2863@1|root,COG2863@2|Bacteria,1R6DK@1224|Proteobacteria	1224|Proteobacteria	C	Pfam cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_3515521_2	522306.CAP2UW1_0898	7.282e-68	244.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,2VSZI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_3515521_6	257310.BB3073	1.375e-52	200.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VQQJ@28216|Betaproteobacteria,3T2PH@506|Alcaligenaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
CMS3_k127_3515521_7	1298593.TOL_1516	3.401e-32	135.0	COG0589@1|root,COG0589@2|Bacteria,1QCT3@1224|Proteobacteria,1SI82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3515521_10	1121413.JMKT01000015_gene237	2.112e-21	105.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria,2MBNK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_3515521_3	443143.GM18_4316	2.653e-65	256.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
CMS3_k127_3515521_0	1565129.JSFF01000002_gene3456	2.32e-77	288.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,2Q8JV@267890|Shewanellaceae	1236|Gammaproteobacteria	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_3515521_12	550540.Fbal_3101	2.324e-06	57.0	2DU5J@1|root,33P0T@2|Bacteria,1NNF8@1224|Proteobacteria,1SH8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3536608_35	345341.KUTG_01076	2.08e-25	108.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_3536608_29	502025.Hoch_3797	5.948e-36	147.0	COG2036@1|root,COG2036@2|Bacteria,1N3S6@1224|Proteobacteria,42UYX@68525|delta/epsilon subdivisions,2WQE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3536608_30	1298880.AUEV01000011_gene2662	6.3e-31	134.0	COG0412@1|root,COG0412@2|Bacteria,2H3SA@201174|Actinobacteria	201174|Actinobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_3536608_37	243233.MCA0647	1.896e-21	106.0	COG1226@1|root,32Y28@2|Bacteria,1NEAT@1224|Proteobacteria,1S588@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
CMS3_k127_3536608_18	1031711.RSPO_c02760	9.659e-63	241.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,2VJ44@28216|Betaproteobacteria,1K0NB@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
CMS3_k127_3536608_38	1144319.PMI16_02726	6.477e-20	98.0	COG2995@1|root,COG2995@2|Bacteria,1RAQ9@1224|Proteobacteria,2VQ5G@28216|Betaproteobacteria,475V0@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
CMS3_k127_3536608_39	404589.Anae109_0493	4.093e-19	101.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS3_k127_3536608_9	292459.STH1727	1.5e-96	329.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
CMS3_k127_3536608_23	331869.BAL199_22024	9.181e-57	225.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,2U4PA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
CMS3_k127_3536608_15	402881.Plav_1981	1.173e-64	255.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria,1JNTH@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
CMS3_k127_3536608_2	469383.Cwoe_3694	1.014e-160	523.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,4CPC4@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3536608_16	589865.DaAHT2_1339	8.399e-64	248.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2MI1U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_3536608_14	1210884.HG799465_gene12157	3.41e-69	270.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_3536608_43	472759.Nhal_3601	5.736e-10	74.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,1RP9Y@1236|Gammaproteobacteria,1WWGU@135613|Chromatiales	135613|Chromatiales	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	PGPGW,TerC
CMS3_k127_3536608_21	483219.LILAB_16735	3.827e-58	230.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CMS3_k127_3536608_33	1238182.C882_0038	7.674e-27	117.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,2JTJ7@204441|Rhodospirillales	204441|Rhodospirillales	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS3_k127_3536608_45	545694.TREPR_0647	9.689e-05	53.0	2EUFF@1|root,33MXQ@2|Bacteria,2J8XM@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
CMS3_k127_3536608_22	886293.Sinac_0205	5.895e-58	224.0	COG0515@1|root,COG0515@2|Bacteria,2J288@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_3536608_36	1131269.AQVV01000025_gene2327	3.986e-25	122.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HTH_31
CMS3_k127_3536608_40	441620.Mpop_0729	1.305e-18	94.0	COG2885@1|root,COG2885@2|Bacteria,1R6QU@1224|Proteobacteria,2TTMS@28211|Alphaproteobacteria,1JTF4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM OmpA MotB domain protein	MA20_39345	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS3_k127_3536608_5	1415778.JQMM01000001_gene2249	6.642e-135	456.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,1J59H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS3_k127_3536608_34	251221.35212664	3.912e-26	122.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3536608_41	330214.NIDE1649	1.292e-13	82.0	2AAUK@1|root,3107C@2|Bacteria,3J1E0@40117|Nitrospirae	40117|Nitrospirae	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
CMS3_k127_3536608_17	1202962.KB907170_gene2407	7.481e-63	223.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
CMS3_k127_3536608_11	1313172.YM304_02290	6.231e-89	312.0	COG0654@1|root,COG0654@2|Bacteria,2I901@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,NAD_binding_8,Trp_halogenase
CMS3_k127_3536608_1	450851.PHZ_c0252	1.691e-167	563.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2KEZN@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_3536608_19	1123368.AUIS01000006_gene572	3.274e-62	245.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,2NCEE@225057|Acidithiobacillales	225057|Acidithiobacillales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS3_k127_3536608_31	1521187.JPIM01000034_gene3560	1.148e-29	134.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,2G6ND@200795|Chloroflexi,376W1@32061|Chloroflexia	32061|Chloroflexia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HD,Response_reg
CMS3_k127_3536608_46	667015.Bacsa_3539	0.0007674	51.0	2A8DZ@1|root,30XFT@2|Bacteria,4PAWR@976|Bacteroidetes,2FXXX@200643|Bacteroidia,4AU0D@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3536608_6	246197.MXAN_6048	5.49e-131	428.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,42P5V@68525|delta/epsilon subdivisions,2WMWE@28221|Deltaproteobacteria,2YU1I@29|Myxococcales	28221|Deltaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CMS3_k127_3536608_24	1123368.AUIS01000018_gene733	1.307e-56	207.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019538,GO:0020037,GO:0030091,GO:0031224,GO:0031226,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
CMS3_k127_3536608_4	1167006.UWK_00007	4.96e-138	455.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria,2MI76@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
CMS3_k127_3536608_13	530564.Psta_3381	2.055e-79	280.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1,MFS_2,PTS_EIIA_1
CMS3_k127_3536608_3	1121440.AUMA01000005_gene2558	1.165e-150	498.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NAQ@68525|delta/epsilon subdivisions,2WJPX@28221|Deltaproteobacteria,2M845@213115|Desulfovibrionales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
CMS3_k127_3536608_20	595460.RRSWK_03509	1.888e-60	217.0	COG4798@1|root,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
CMS3_k127_3536608_8	247634.GPB2148_2386	4.082e-115	382.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1J7IT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	3.1.4.54	ko:K13985	ko04723,map04723	-	-	-	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS3_k127_3536608_7	1038858.AXBA01000003_gene4299	5.493e-117	391.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,3EYIW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS3_k127_3536608_28	1000565.METUNv1_02960	2.488e-36	159.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,2KWQ1@206389|Rhodocyclales	206389|Rhodocyclales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	dfrA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
CMS3_k127_3536608_10	1499967.BAYZ01000016_gene6483	3.754e-89	305.0	COG0253@1|root,COG0253@2|Bacteria,2NPFA@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_3536608_32	595494.Tola_1000	2.219e-27	128.0	COG0818@1|root,COG0818@2|Bacteria,1QJH1@1224|Proteobacteria,1SBNJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Prokaryotic diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS3_k127_3536608_25	62928.azo1589	9.791e-55	205.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,2KWDI@206389|Rhodocyclales	206389|Rhodocyclales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS3_k127_3536608_26	1123288.SOV_4c06510	2.402e-54	210.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4H24X@909932|Negativicutes	909932|Negativicutes	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS3_k127_3536608_27	1144310.PMI07_001577	3.592e-37	163.0	COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,2U0KA@28211|Alphaproteobacteria,4BBE8@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
CMS3_k127_3536608_0	861299.J421_2862	1.315e-244	764.0	COG0499@1|root,COG0499@2|Bacteria,1ZTEF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS3_k127_3536608_12	391625.PPSIR1_20719	7.591e-86	299.0	COG1408@1|root,COG1408@2|Bacteria,1Q3AY@1224|Proteobacteria,43923@68525|delta/epsilon subdivisions,2X47Q@28221|Deltaproteobacteria,2YYFK@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_3536608_44	502025.Hoch_0365	9.454e-07	51.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42QF3@68525|delta/epsilon subdivisions,2WKPQ@28221|Deltaproteobacteria,2Z2XW@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS3_k127_3550502_17	1292034.OR37_01977	1.441e-25	108.0	COG1024@1|root,COG1024@2|Bacteria,1RC0E@1224|Proteobacteria,2UCQV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_3550502_6	68570.DC74_1106	6.786e-120	400.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3550502_3	487521.OCU_43080	7.664e-130	428.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3550502_9	43354.JOIJ01000009_gene2772	9.513e-103	345.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4E0Y2@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_3550502_13	1206743.BAGM01000116_gene1447	2.651e-48	182.0	COG1024@1|root,COG1024@2|Bacteria,2I9VC@201174|Actinobacteria,4FWJ5@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_3550502_16	710685.MycrhN_0101	7.807e-28	118.0	COG0346@1|root,COG0346@2|Bacteria,2GPS7@201174|Actinobacteria,23AU5@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_3550502_4	680198.SCAB_51901	9.412e-124	411.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	ltp2	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
CMS3_k127_3550502_14	105420.BBPO01000006_gene3022	3.228e-40	154.0	COG1545@1|root,COG1545@2|Bacteria,2IHZR@201174|Actinobacteria,2NIFG@228398|Streptacidiphilus	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_3550502_7	1144307.PMI04_00622	1.099e-119	396.0	COG2030@1|root,COG2030@2|Bacteria,1NTV7@1224|Proteobacteria,2UQFU@28211|Alphaproteobacteria,2K8I3@204457|Sphingomonadales	204457|Sphingomonadales	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
CMS3_k127_3550502_8	1206730.BAGA01000171_gene2202	9.731e-119	418.0	COG0318@1|root,COG0318@2|Bacteria,2IEKP@201174|Actinobacteria,4FUBQ@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3550502_12	1120950.KB892770_gene1372	1.119e-53	207.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DRH1@85009|Propionibacteriales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3550502_11	1246484.D479_01595	6.361e-58	233.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli,3NDI9@45667|Halobacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS3_k127_3550502_2	1394178.AWOO02000015_gene7055	8.44e-137	464.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EHHR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_3550502_5	1207055.C100_11150	5.478e-121	400.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2K16D@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3550502_20	1538295.JY96_13910	1.824e-07	58.0	COG1361@1|root,COG1686@1|root,COG1361@2|Bacteria,COG1686@2|Bacteria,1PWJU@1224|Proteobacteria,2W081@28216|Betaproteobacteria,1KN3Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,TSP_3
CMS3_k127_3550502_15	469383.Cwoe_4936	1.199e-38	151.0	2EE69@1|root,3380V@2|Bacteria,2GR09@201174|Actinobacteria,4CTGN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3550502_18	1122247.C731_0984	1.212e-13	81.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_3550502_0	1207055.C100_18075	6.29e-270	876.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS3_k127_3550502_1	1207055.C100_18070	8.123e-270	842.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS3_k127_3550502_10	1283287.KB822580_gene1598	2.715e-81	281.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4DQMQ@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3584748_7	1168065.DOK_02681	7.906e-47	179.0	COG1262@1|root,COG3509@1|root,COG1262@2|Bacteria,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	CE1	-	Abhydrolase_2,Esterase_phd,FGE-sulfatase,VPEP
CMS3_k127_3584748_9	402881.Plav_1780	6.044e-41	161.0	COG2050@1|root,COG2050@2|Bacteria,1REK6@1224|Proteobacteria,2U8H6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_3584748_1	1499967.BAYZ01000069_gene1839	7.435e-95	324.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS3_k127_3584748_0	1313172.YM304_33470	0.0	1152.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,2GKBW@201174|Actinobacteria	201174|Actinobacteria	C	indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR,POR_N,TPP_enzyme_C
CMS3_k127_3584748_4	926550.CLDAP_25100	6.551e-87	292.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS3_k127_3584748_5	458817.Shal_2289	1.715e-81	306.0	28N53@1|root,2ZBAC@2|Bacteria,1R6W1@1224|Proteobacteria,1SIV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3584748_3	521098.Aaci_1209	9.089e-89	307.0	COG1960@1|root,COG1960@2|Bacteria,1VQUR@1239|Firmicutes,4HU1X@91061|Bacilli	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	ko:K04117	ko00362,ko01120,map00362,map01120	M00540	R05619	RC02035	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3584748_6	357808.RoseRS_0422	1.886e-50	191.0	COG3394@1|root,COG3394@2|Bacteria,2G6X5@200795|Chloroflexi	200795|Chloroflexi	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS3_k127_3584748_2	443598.AUFA01000010_gene111	1.39e-90	311.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,3JU48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	MA20_32380	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3584748_10	247639.MGP2080_10543	1.955e-20	100.0	COG4319@1|root,COG4319@2|Bacteria,1QXYE@1224|Proteobacteria	1224|Proteobacteria	S	Nuclear transport factor 2 (NTF2) domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
CMS3_k127_3584748_8	1121468.AUBR01000022_gene2777	4.011e-42	160.0	COG0739@1|root,COG0739@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia,42GK2@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
CMS3_k127_360533_1	264462.Bd1201	4.033e-144	477.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2MSUE@213481|Bdellovibrionales,2WJE6@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_360533_4	1122611.KB903939_gene435	2.152e-69	266.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4EHHI@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_360533_6	318424.EU78_08610	1.383e-06	55.0	COG3173@1|root,COG3173@2|Bacteria,2IQRM@201174|Actinobacteria,23AJ7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_360533_0	886293.Sinac_1421	1.812e-148	492.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_360533_2	448385.sce5982	1.021e-116	386.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,42QED@68525|delta/epsilon subdivisions,2WJWR@28221|Deltaproteobacteria,2Z18F@29|Myxococcales	28221|Deltaproteobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS3_k127_360533_3	880073.Calab_1912	4.867e-71	249.0	COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_360533_5	1298867.AUES01000010_gene5841	1.315e-41	162.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,2TT9T@28211|Alphaproteobacteria,3JTG7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_06725	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_366893_0	391625.PPSIR1_26703	1.135e-99	336.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YZKE@29|Myxococcales	28221|Deltaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_366893_3	710111.FraQA3DRAFT_4637	3.352e-76	291.0	COG4191@1|root,COG4191@2|Bacteria,2GSHF@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_366893_4	56110.Oscil6304_5208	4.078e-50	198.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_366893_1	1239962.C943_02139	6.026e-83	297.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_366893_10	1120968.AUBX01000017_gene1895	3.136e-15	88.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3
CMS3_k127_366893_9	1120965.AUBV01000016_gene94	1.215e-19	102.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
CMS3_k127_366893_6	1267533.KB906736_gene1328	1.066e-41	173.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_366893_8	886293.Sinac_3509	2.638e-35	158.0	COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_366893_2	1254432.SCE1572_47310	1.134e-82	291.0	COG1475@1|root,COG1475@2|Bacteria,1Q2AH@1224|Proteobacteria,437X8@68525|delta/epsilon subdivisions,2X9QN@28221|Deltaproteobacteria,2YUMN@29|Myxococcales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_366893_5	765914.ThisiDRAFT_2077	3.516e-46	180.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1WXSW@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_366893_7	420324.KI912045_gene4108	2.752e-37	157.0	COG0265@1|root,COG0265@2|Bacteria,1MV63@1224|Proteobacteria,2TS54@28211|Alphaproteobacteria,1JRCY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_3694536_1	644283.Micau_2846	7.625e-57	214.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3694536_0	378806.STAUR_8391	2.647e-126	418.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2X3TP@28221|Deltaproteobacteria,2YX2Z@29|Myxococcales	28221|Deltaproteobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_3698003_35	439235.Dalk_3322	1.344e-12	69.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WJS7@28221|Deltaproteobacteria,2MIWA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3698003_23	58123.JOFJ01000003_gene2210	4.195e-44	172.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4EH41@85012|Streptosporangiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_3698003_16	1448389.BAVQ01000029_gene645	1.345e-73	267.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3698003_11	1382356.JQMP01000003_gene1697	6.513e-85	299.0	COG2377@1|root,COG2377@2|Bacteria,2G7X8@200795|Chloroflexi,27YT7@189775|Thermomicrobia	189775|Thermomicrobia	O	Anhydro-N-acetylmuramic acid kinase	-	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS3_k127_3698003_20	1502851.FG93_02100	4.265e-49	184.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria,3JTWA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	MA20_22080	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_3698003_32	502025.Hoch_6775	2.024e-27	130.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
CMS3_k127_3698003_37	1122180.Lokhon_00710	1.491e-11	78.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,2P8T1@245186|Loktanella	28211|Alphaproteobacteria	S	related to Ser Thr protein kinases	MA20_24090	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,TsaE
CMS3_k127_3698003_6	1229172.JQFA01000004_gene2017	1.761e-109	369.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1G3TV@1117|Cyanobacteria,1H9HJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleoside recognition	-	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
CMS3_k127_3698003_15	404589.Anae109_3925	1.869e-75	274.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42R96@68525|delta/epsilon subdivisions,2WMVV@28221|Deltaproteobacteria,2YXAR@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS3_k127_3698003_31	1304888.ATWF01000001_gene766	4.86e-29	126.0	COG0741@1|root,COG0741@2|Bacteria,2GFMV@200930|Deferribacteres	200930|Deferribacteres	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
CMS3_k127_3698003_40	637910.ROD_46901	0.0001474	50.0	2DSYK@1|root,33HYD@2|Bacteria,1NJ6M@1224|Proteobacteria,1SIGD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3698003_27	1254432.SCE1572_46760	7.857e-35	140.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2YVK3@29|Myxococcales	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS3_k127_3698003_25	880072.Desac_2926	1.149e-43	177.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MQHK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_3698003_9	1249627.D779_0920	1.96e-98	337.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_3698003_12	290512.Paes_0871	2.528e-79	297.0	COG1030@1|root,COG1030@2|Bacteria,1FEQ2@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S14 ClpP	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
CMS3_k127_3698003_10	1123248.KB893314_gene3563	1.444e-91	310.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1IRDU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_3698003_22	1304883.KI912532_gene1972	1.978e-46	185.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,2KUKU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS3_k127_3698003_26	765913.ThidrDRAFT_3566	9.968e-42	175.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1WW0U@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could regulate a protease	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS3_k127_3698003_39	398767.Glov_2588	6.591e-08	64.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS3_k127_3698003_14	880072.Desac_2284	1.148e-76	268.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2MQCP@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS3_k127_3698003_30	243231.GSU1488	1.176e-29	132.0	COG0392@1|root,COG0392@2|Bacteria,1N7DR@1224|Proteobacteria,42N4R@68525|delta/epsilon subdivisions,2WS5Z@28221|Deltaproteobacteria,43TTU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_3698003_0	1121918.ARWE01000001_gene1841	3.769e-235	740.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
CMS3_k127_3698003_1	404589.Anae109_0668	4.367e-188	592.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_3698003_4	502025.Hoch_4826	1.646e-119	396.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2YU38@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_3698003_13	335543.Sfum_0119	7.885e-78	282.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
CMS3_k127_3698003_2	1232410.KI421416_gene2592	8.36e-154	526.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_3698003_24	391625.PPSIR1_36954	5.679e-44	181.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_3698003_3	290397.Adeh_0639	1.915e-139	456.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_3698003_34	290397.Adeh_0640	3.998e-14	81.0	COG1396@1|root,COG1396@2|Bacteria,1QYFR@1224|Proteobacteria,43CBW@68525|delta/epsilon subdivisions,2X7MR@28221|Deltaproteobacteria,2Z2CU@29|Myxococcales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
CMS3_k127_3698003_7	1297742.A176_05319	1.427e-105	359.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_3698003_33	338963.Pcar_2137	8.333e-19	93.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I2@1224|Proteobacteria,42VWH@68525|delta/epsilon subdivisions,2WS2H@28221|Deltaproteobacteria,43VGF@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
CMS3_k127_3698003_28	404380.Gbem_1548	2.056e-33	137.0	COG3167@1|root,COG3167@2|Bacteria,1MZZ4@1224|Proteobacteria,43B6P@68525|delta/epsilon subdivisions,2X6K9@28221|Deltaproteobacteria,43TSB@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
CMS3_k127_3698003_38	378806.STAUR_6442	2.666e-10	69.0	COG3168@1|root,COG3168@2|Bacteria,1NMC2@1224|Proteobacteria,42WTR@68525|delta/epsilon subdivisions,2WSTB@28221|Deltaproteobacteria,2YXXY@29|Myxococcales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
CMS3_k127_3698003_8	290397.Adeh_0645	5.055e-103	375.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS3_k127_3698003_5	1502852.FG94_01382	1.104e-110	378.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,4725Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CMS3_k127_3698003_36	448385.sce3925	7.014e-12	74.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,2YVP4@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3698003_19	1125863.JAFN01000001_gene2274	7.174e-54	194.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS3_k127_3698003_29	1157490.EL26_08500	1.456e-32	137.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,27875@186823|Alicyclobacillaceae	91061|Bacilli	H	Biotin/lipoate A/B protein ligase family	lipM	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS3_k127_3698003_18	404589.Anae109_0696	1.12e-54	220.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
CMS3_k127_3698003_17	404589.Anae109_0697	9.402e-63	232.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42MM0@68525|delta/epsilon subdivisions,2WKXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
CMS3_k127_3698003_21	1211579.PP4_27050	1.28e-47	175.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1YV7F@136845|Pseudomonas putida group	1236|Gammaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS3_k127_3717697_10	75379.Tint_2880	1.62e-13	73.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,1KJXX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS3_k127_3717697_6	638302.HMPREF0908_0014	2.173e-41	167.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4H31R@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS3_k127_3717697_8	1121918.ARWE01000001_gene2287	1.241e-26	124.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516,ko:K05801	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,TerB,WD40
CMS3_k127_3717697_11	1297742.A176_07465	1.747e-07	63.0	COG3064@1|root,COG3215@1|root,COG3064@2|Bacteria,COG3215@2|Bacteria,1Q3B9@1224|Proteobacteria,4392F@68525|delta/epsilon subdivisions,2X485@28221|Deltaproteobacteria,2YYGF@29|Myxococcales	28221|Deltaproteobacteria	MNU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_3717697_1	335543.Sfum_2243	1.082e-112	368.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MQ8C@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
CMS3_k127_3717697_9	1341679.P253_02003	4.475e-25	111.0	COG0239@1|root,COG0239@2|Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS3_k127_3717697_14	1192034.CAP_4294	0.0009685	48.0	COG3816@1|root,COG3816@2|Bacteria,1R33P@1224|Proteobacteria,42VZ9@68525|delta/epsilon subdivisions,2WRED@28221|Deltaproteobacteria,2YVWQ@29|Myxococcales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
CMS3_k127_3717697_4	1232410.KI421412_gene349	1.826e-50	194.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,43UU6@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Biotin/lipoate A/B protein ligase family	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
CMS3_k127_3717697_2	448385.sce6586	2.745e-95	326.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2X5JH@28221|Deltaproteobacteria,2YZ22@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_3717697_5	1146883.BLASA_3825	1.217e-42	179.0	COG1183@1|root,COG1183@2|Bacteria,2IC3M@201174|Actinobacteria	201174|Actinobacteria	I	phosphatidylcholine synthase	pcs	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_3717697_0	1297742.A176_03889	2.55e-117	400.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2YY0V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS3_k127_3717697_3	1500301.JQMF01000001_gene63	1.464e-71	252.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,4B8Z7@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	DnaJ C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
CMS3_k127_3717697_7	1125863.JAFN01000001_gene3393	6.82e-36	144.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS3_k127_3737066_1	324602.Caur_1632	1.958e-20	94.0	COG1088@1|root,COG1088@2|Bacteria,2GA89@200795|Chloroflexi,3780Y@32061|Chloroflexia	32061|Chloroflexia	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_3737066_0	661478.OP10G_2900	2.479e-45	169.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528,ko:K20444	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko01005,ko02000,ko03009	4.D.1.3	GT2,GT4	-	CTP_transf_like,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_12,Methyltransf_23,RrnaAD
CMS3_k127_3742411_8	443143.GM18_4316	3.327e-63	248.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
CMS3_k127_3742411_1	1328313.DS2_05440	2.357e-148	484.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,46455@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS3_k127_3742411_10	754477.Q7C_441	3.26e-44	180.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,462HD@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_3742411_4	1282876.BAOK01000001_gene3625	7.483e-120	397.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2U6SB@28211|Alphaproteobacteria,4BTBH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_3742411_15	1242864.D187_007191	1.7e-24	122.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
CMS3_k127_3742411_2	96561.Dole_0520	6.885e-140	457.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46,5.1.3.10,5.1.3.2	ko:K01710,ko:K01784,ko:K12454	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R04266,R06513	RC00289,RC00402,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd,dTDP_sugar_isom
CMS3_k127_3742411_6	394503.Ccel_0970	1.069e-69	258.0	COG1209@1|root,COG1209@2|Bacteria,1VXFW@1239|Firmicutes	1239|Firmicutes	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_3742411_16	1161401.ASJA01000004_gene2169	2.384e-22	106.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2TWPJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_3742411_11	795797.C497_10933	5.788e-40	173.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3742411_9	96561.Dole_2412	3.792e-59	216.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
CMS3_k127_3742411_7	344747.PM8797T_04335	2.272e-68	251.0	COG3119@1|root,COG3119@2|Bacteria,2J2Z5@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_3742411_12	459495.SPLC1_S033620	8.462e-35	150.0	28KEP@1|root,2ZBG5@2|Bacteria,1G36F@1117|Cyanobacteria,1H96D@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3742411_18	28229.ND2E_2525	1.088e-17	88.0	COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,2Q74R@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3,Glutaredoxin
CMS3_k127_3742411_3	479434.Sthe_2433	4.854e-127	428.0	COG0277@1|root,COG0277@2|Bacteria,2G7TD@200795|Chloroflexi	200795|Chloroflexi	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
CMS3_k127_3742411_13	335543.Sfum_3681	7.831e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,42UZX@68525|delta/epsilon subdivisions,2WQ98@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
CMS3_k127_3742411_5	247633.GP2143_09045	5.235e-78	286.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,1JA4A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_3742411_0	247633.GP2143_09040	8.145e-292	950.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J8T8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_3780601_19	545276.KB898729_gene1500	5.507e-29	125.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,1RZ5C@1236|Gammaproteobacteria,1WX9Q@135613|Chromatiales	135613|Chromatiales	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_3780601_3	396588.Tgr7_2360	1.584e-157	521.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_3780601_4	234267.Acid_4624	1.277e-128	439.0	COG0367@1|root,COG0367@2|Bacteria,3Y6CC@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_3780601_17	1089553.Tph_c02780	4.196e-41	176.0	COG0438@1|root,COG0707@1|root,COG0438@2|Bacteria,COG0707@2|Bacteria,1TRCM@1239|Firmicutes,25BWB@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_3780601_7	864051.BurJ1DRAFT_3150	8.003e-119	400.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,1KK9E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Male sterility protein	wbpP	-	5.1.3.7	ko:K02473	ko00520,ko01100,map00520,map01100	-	R00418	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_3780601_23	1121033.AUCF01000001_gene2380	1.132e-10	74.0	COG3307@1|root,COG3307@2|Bacteria,1QYW7@1224|Proteobacteria,2UK9T@28211|Alphaproteobacteria,2JY4G@204441|Rhodospirillales	204441|Rhodospirillales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_3780601_11	1347342.BN863_29260	1.94e-54	207.0	COG0438@1|root,COG0438@2|Bacteria,4NIN2@976|Bacteroidetes,1I114@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3780601_16	1234364.AMSF01000010_gene551	9.743e-43	176.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,1X32Y@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_3780601_14	1121413.JMKT01000015_gene262	9.128e-45	184.0	COG2244@1|root,COG2244@2|Bacteria,1QZC3@1224|Proteobacteria,42U79@68525|delta/epsilon subdivisions,2WQ6Z@28221|Deltaproteobacteria,2MFJW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
CMS3_k127_3780601_5	644801.Psest_0249	5.13e-128	422.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,1Z2HQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECOK1_1307.ECOK1_4232,iECS88_1305.ECS88_4208,iECs_1301.ECs4719,iEcSMS35_1347.EcSMS35_4150,iG2583_1286.G2583_4580,iPC815.YPO3864,iSDY_1059.SDY_3962,iSSON_1240.SSON_3958,iUMN146_1321.UM146_19070,iZ_1308.Z5297	Epimerase_2
CMS3_k127_3780601_8	1173029.JH980292_gene2498	4.951e-116	407.0	COG0726@1|root,COG0726@2|Bacteria,1G3JU@1117|Cyanobacteria,1HABD@1150|Oscillatoriales	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_3780601_1	118166.JH976537_gene15	6.127e-172	552.0	COG1232@1|root,COG1232@2|Bacteria,1G465@1117|Cyanobacteria,1H9AU@1150|Oscillatoriales	1117|Cyanobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_3780601_18	41431.PCC8801_2281	7.806e-30	139.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,3KHHI@43988|Cyanothece	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS3_k127_3780601_22	1499967.BAYZ01000090_gene4941	4.984e-11	76.0	2DDA6@1|root,2ZH98@2|Bacteria	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT
CMS3_k127_3780601_10	1173029.JH980292_gene2486	5.57e-76	275.0	COG0110@1|root,COG0110@2|Bacteria,1G65X@1117|Cyanobacteria,1H84W@1150|Oscillatoriales	1117|Cyanobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
CMS3_k127_3780601_6	272134.KB731324_gene4077	4.8e-126	436.0	COG0673@1|root,COG0673@2|Bacteria,1G0M6@1117|Cyanobacteria,1HA0M@1150|Oscillatoriales	1117|Cyanobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_3780601_2	530564.Psta_1436	8.378e-158	539.0	COG0399@1|root,COG0399@2|Bacteria,2IYSK@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_3780601_0	1123508.JH636439_gene1510	5.171e-184	605.0	COG0463@1|root,COG0726@1|root,COG0463@2|Bacteria,COG0726@2|Bacteria,2IWT2@203682|Planctomycetes	203682|Planctomycetes	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Glycos_transf_2,Polysacc_deac_1
CMS3_k127_3780601_9	1121456.ATVA01000012_gene2804	5.463e-82	286.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,43F2S@68525|delta/epsilon subdivisions,2X35V@28221|Deltaproteobacteria,2ME5E@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3780601_20	179408.Osc7112_0435	1.825e-21	108.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS3_k127_3780601_15	1123269.NX02_24205	4.437e-44	176.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_3780601_13	765911.Thivi_4061	6.573e-45	186.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,1RSI9@1236|Gammaproteobacteria,1X13K@135613|Chromatiales	135613|Chromatiales	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS3_k127_3780601_21	1286106.MPL1_00190	4.409e-15	89.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	eight transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS3_k127_3780601_12	338966.Ppro_2443	5.04e-50	194.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,43U07@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS3_k127_3790011_4	1254432.SCE1572_17000	2.184e-98	333.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2WMFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_3790011_1	1110502.TMO_0118	1.067e-280	878.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JZ17@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS3_k127_3790011_15	1089552.KI911559_gene1249	7.982e-65	234.0	COG1703@1|root,COG1703@2|Bacteria,1R44P@1224|Proteobacteria,2TW2E@28211|Alphaproteobacteria,2JR6W@204441|Rhodospirillales	204441|Rhodospirillales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_3790011_21	1249627.D779_3650	9.933e-37	151.0	COG1309@1|root,COG1309@2|Bacteria,1N1X6@1224|Proteobacteria,1S9GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3790011_9	572477.Alvin_1456	8.156e-70	258.0	COG1566@1|root,COG1566@2|Bacteria,1RBK7@1224|Proteobacteria,1S241@1236|Gammaproteobacteria,1X2HT@135613|Chromatiales	135613|Chromatiales	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_3
CMS3_k127_3790011_3	572477.Alvin_1457	1.78e-118	388.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWJJ@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3790011_2	765913.ThidrDRAFT_4551	4.357e-130	439.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1WXQP@135613|Chromatiales	135613|Chromatiales	U	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_3790011_0	497964.CfE428DRAFT_4093	0.0	1388.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia	74201|Verrucomicrobia	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
CMS3_k127_3790011_29	1123501.KB902288_gene1791	8.035e-17	96.0	COG2267@1|root,COG2267@2|Bacteria,1R4AT@1224|Proteobacteria,2U5CU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_3790011_22	439235.Dalk_5197	8.589e-36	147.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42W27@68525|delta/epsilon subdivisions,2X2CN@28221|Deltaproteobacteria,2MP21@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_3790011_24	314285.KT71_02392	1.214e-24	111.0	29GUQ@1|root,2ZIQ9@2|Bacteria,1P89M@1224|Proteobacteria,1STDV@1236|Gammaproteobacteria,1JBAC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_3790011_18	1144275.COCOR_06487	4.433e-53	198.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS3_k127_3790011_8	589865.DaAHT2_0905	4.414e-71	252.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2MIG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS3_k127_3790011_16	671143.DAMO_0884	1.041e-63	231.0	COG2887@1|root,COG2887@2|Bacteria,2NQTZ@2323|unclassified Bacteria	2|Bacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1
CMS3_k127_3790011_11	1121033.AUCF01000018_gene5817	7.138e-69	241.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,2JQE0@204441|Rhodospirillales	204441|Rhodospirillales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CMS3_k127_3790011_27	644282.Deba_1384	4.981e-20	103.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_3790011_30	880073.Calab_1706	5.541e-16	92.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS3_k127_3790011_23	1340493.JNIF01000003_gene3993	9.346e-33	144.0	COG1524@1|root,COG1524@2|Bacteria,3Y3RC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
CMS3_k127_3790011_6	404589.Anae109_4145	9.745e-85	290.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_3790011_7	290397.Adeh_0423	1.075e-72	257.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YU8R@29|Myxococcales	28221|Deltaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_3790011_20	1254432.SCE1572_16555	3.454e-38	159.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2YVW1@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
CMS3_k127_3790011_28	935565.JAEM01000002_gene3756	2.097e-18	89.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2UC33@28211|Alphaproteobacteria,2PX61@265|Paracoccus	28211|Alphaproteobacteria	P	Rieske-like [2Fe-2S] domain	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
CMS3_k127_3790011_14	1131269.AQVV01000001_gene1399	4.085e-66	235.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	pksB	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_3790011_17	639030.JHVA01000001_gene1718	1.401e-55	203.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria,2JK7K@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_3790011_10	1121920.AUAU01000023_gene2418	1.044e-69	248.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS3_k127_3790011_13	1499967.BAYZ01000068_gene1954	2.828e-67	238.0	COG0231@1|root,COG0231@2|Bacteria,2NPID@2323|unclassified Bacteria	2|Bacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS3_k127_3790011_5	502025.Hoch_5960	1.142e-87	304.0	COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YUHG@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_3790011_12	671143.DAMO_2747	4.574e-68	243.0	COG2378@1|root,COG2378@2|Bacteria,2NPY6@2323|unclassified Bacteria	2|Bacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
CMS3_k127_3790011_25	1227499.C493_11192	8.783e-24	108.0	COG2020@1|root,arCOG03580@2157|Archaea,2XY7P@28890|Euryarchaeota,23WBN@183963|Halobacteria	183963|Halobacteria	O	protein-S-isoprenylcysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_3790011_19	1280944.HY17_04800	1.528e-41	175.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria,43XPN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	COG0208 Ribonucleotide reductase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_3790011_31	457425.XNR_0873	4.726e-15	84.0	COG1309@1|root,COG1309@2|Bacteria,2IIND@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3790011_32	443598.AUFA01000012_gene4852	3.317e-08	67.0	COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,2U1SN@28211|Alphaproteobacteria,3JR7E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
CMS3_k127_3790011_26	713586.KB900536_gene1931	1.271e-22	104.0	COG0810@1|root,COG3210@1|root,COG0810@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	infB	-	-	ko:K02519,ko:K03832	-	-	-	-	ko00000,ko02000,ko03012,ko03029	2.C.1.1	-	-	CarbopepD_reg_2,Gram_pos_anchor,HtaA,TonB_C,YSIRK_signal,YXWGXW
CMS3_k127_384605_3	882.DVU_1173	2.329e-07	56.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MA1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS3_k127_384605_1	518766.Rmar_0136	1.655e-150	503.0	COG1509@1|root,COG1509@2|Bacteria,4NJ79@976|Bacteroidetes,1FJ3Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Lysine-2,3-aminomutase	ablA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
CMS3_k127_384605_2	1089550.ATTH01000001_gene1570	1.263e-98	334.0	COG1181@1|root,COG1181@2|Bacteria,4PEAY@976|Bacteroidetes,1FIPX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_384605_4	903818.KI912268_gene2695	5.153e-06	56.0	COG5652@1|root,COG5652@2|Bacteria,3Y82N@57723|Acidobacteria	57723|Acidobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS3_k127_384605_0	237368.SCABRO_02555	1.309e-165	546.0	COG1966@1|root,COG1966@2|Bacteria,2IWZE@203682|Planctomycetes	203682|Planctomycetes	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
CMS3_k127_3881089_0	1232410.KI421416_gene2683	9.072e-278	872.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QJP@68525|delta/epsilon subdivisions,2WMET@28221|Deltaproteobacteria,43UGS@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Multicopper oxidase	ompC	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2
CMS3_k127_3881089_4	338963.Pcar_2604	3.818e-41	162.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_3881089_7	269799.Gmet_2164	7.476e-11	74.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	iAF987.Gmet_2161	FKBP_C,FKBP_N
CMS3_k127_3881089_1	1122221.JHVI01000022_gene1208	5.919e-143	481.0	COG0156@1|root,COG0156@2|Bacteria,1WIXA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_3881089_2	526227.Mesil_2958	4.033e-128	418.0	COG0451@1|root,COG0451@2|Bacteria,1WNCR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS3_k127_3881089_8	1192034.CAP_1358	3.989e-10	76.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
CMS3_k127_3881089_6	357808.RoseRS_0010	4.926e-17	98.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_3881089_3	404380.Gbem_1001	2.416e-56	216.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_3881089_5	667632.KB890193_gene3329	4.606e-31	141.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_4,zinc_ribbon_2
CMS3_k127_3897725_4	439235.Dalk_1881	8.645e-92	329.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3897725_0	1121937.AUHJ01000010_gene1754	3.707e-153	502.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,466JE@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,HAD
CMS3_k127_3897725_1	1380394.JADL01000007_gene4528	1.014e-141	465.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2JPTH@204441|Rhodospirillales	204441|Rhodospirillales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_3897725_5	643473.KB235930_gene3547	1.432e-31	133.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1HJH3@1161|Nostocales	1117|Cyanobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS3_k127_3897725_3	1333998.M2A_2155	3.112e-99	333.0	COG2267@1|root,COG2267@2|Bacteria,1R9GQ@1224|Proteobacteria,2U3YF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_3897725_2	228405.HNE_1399	3.107e-141	456.0	COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2TRU9@28211|Alphaproteobacteria,43X57@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS3_k127_3918581_2	1144275.COCOR_07151	5.481e-39	164.0	COG2885@1|root,COG2885@2|Bacteria,1R2QU@1224|Proteobacteria,43DG3@68525|delta/epsilon subdivisions,2X8N2@28221|Deltaproteobacteria,2Z3MX@29|Myxococcales	28221|Deltaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3918581_0	886293.Sinac_2608	1.452e-114	393.0	COG0075@1|root,COG0075@2|Bacteria,2IYEK@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_3918581_1	1379698.RBG1_1C00001G1870	3.205e-105	358.0	COG0232@1|root,COG0232@2|Bacteria,2NP3S@2323|unclassified Bacteria	2|Bacteria	F	Phosphohydrolase-associated domain	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS3_k127_3923704_2	134676.ACPL_7290	1.614e-67	244.0	COG0438@1|root,COG0438@2|Bacteria,2GJBP@201174|Actinobacteria,4DGWW@85008|Micromonosporales	201174|Actinobacteria	M	Stealth protein CR3, conserved region 3	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
CMS3_k127_3923704_3	394221.Mmar10_1181	1.843e-18	100.0	COG4714@1|root,COG4714@2|Bacteria,1QV7Y@1224|Proteobacteria,2U2GT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_3923704_1	1123242.JH636435_gene2617	1.146e-69	253.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_3923704_0	595460.RRSWK_01941	5.18e-72	262.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3929261_0	247634.GPB2148_96	6.768e-213	684.0	2DBUU@1|root,2ZB7U@2|Bacteria,1R8WF@1224|Proteobacteria,1SMN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS3_k127_3929261_7	1380356.JNIK01000001_gene2182	4.986e-98	332.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4ESZE@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_3929261_17	391625.PPSIR1_41664	3.754e-54	217.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,439F3@68525|delta/epsilon subdivisions,2X4QF@28221|Deltaproteobacteria,2YZE7@29|Myxococcales	28221|Deltaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_3929261_19	876269.ARWA01000001_gene2157	6.763e-27	116.0	COG3703@1|root,COG3703@2|Bacteria,1RAZY@1224|Proteobacteria,2U6EG@28211|Alphaproteobacteria,3NAXT@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	AIG2-like family	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2
CMS3_k127_3929261_9	1282876.BAOK01000002_gene688	1.432e-89	304.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TVZ2@28211|Alphaproteobacteria,4BQZC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Ndr family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_3929261_1	1282876.BAOK01000001_gene2473	7.961e-162	531.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2UAFI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_3929261_2	525368.HMPREF0591_0862	1.345e-146	480.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria,232HJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
CMS3_k127_3929261_6	1229780.BN381_150064	2.177e-100	348.0	COG1409@1|root,COG1409@2|Bacteria,2IDNH@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_3929261_3	2074.JNYD01000024_gene2844	3.33e-146	504.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_3929261_16	1173024.KI912149_gene4953	1.355e-55	223.0	COG3153@1|root,COG3153@2|Bacteria,1G3A1@1117|Cyanobacteria,1JKMA@1189|Stigonemataceae	1117|Cyanobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS3_k127_3929261_10	1207058.L53_14590	4.701e-83	284.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2TVBC@28211|Alphaproteobacteria,43ZIR@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_3929261_8	1282876.BAOK01000001_gene1314	1.266e-91	314.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_3929261_18	1463821.JOGR01000010_gene3943	3.44e-32	143.0	COG0346@1|root,COG0346@2|Bacteria,2GRGB@201174|Actinobacteria,4EZQF@85014|Glycomycetales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
CMS3_k127_3929261_4	1207063.P24_13348	3.96e-113	385.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TUVG@28211|Alphaproteobacteria,2JV0Z@204441|Rhodospirillales	204441|Rhodospirillales	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3929261_11	1123279.ATUS01000001_gene1106	2.954e-81	279.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1RYQM@1236|Gammaproteobacteria,1J5QB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_3929261_14	247634.GPB2148_1774	3.129e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,1R6NY@1224|Proteobacteria,1S0VU@1236|Gammaproteobacteria,1JAJQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_3929261_13	1200792.AKYF01000021_gene5366	1.133e-73	259.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,4ITBS@91061|Bacilli,274QS@186822|Paenibacillaceae	91061|Bacilli	S	KR domain	pksE	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3929261_5	1449063.JMLS01000005_gene3090	8.936e-107	355.0	COG2175@1|root,COG2175@2|Bacteria,1UY74@1239|Firmicutes,4HBK4@91061|Bacilli,26SWW@186822|Paenibacillaceae	91061|Bacilli	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_3929261_12	298654.FraEuI1c_2538	1.145e-79	275.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_3929261_15	1206737.BAGF01000059_gene3905	2.165e-62	223.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FV7A@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3936683_13	1353528.DT23_06545	2.274e-41	164.0	COG0664@1|root,COG0664@2|Bacteria,1PHS6@1224|Proteobacteria,2V8JA@28211|Alphaproteobacteria,2XNTW@285107|Thioclava	28211|Alphaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_3936683_19	641526.ADIWIN_0071	1.717e-12	80.0	COG3391@1|root,COG3391@2|Bacteria,4NIW7@976|Bacteroidetes,1I0II@117743|Flavobacteriia	976|Bacteroidetes	O	ubiquitin	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS3_k127_3936683_21	1297742.A176_03661	5.452e-08	65.0	COG5184@1|root,COG5184@2|Bacteria,1NCZK@1224|Proteobacteria,43C3B@68525|delta/epsilon subdivisions,2X7DY@28221|Deltaproteobacteria,2Z0HN@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	mtsC	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_3936683_2	946362.XP_004997743.1	5.693e-153	532.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_3936683_6	1282876.BAOK01000001_gene3166	6.899e-125	409.0	COG0673@1|root,COG0673@2|Bacteria,1MXDE@1224|Proteobacteria,2TSGR@28211|Alphaproteobacteria,4BRMC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_3936683_7	1254432.SCE1572_03940	6.9e-105	376.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria	1224|Proteobacteria	L	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS3_k127_3936683_18	637905.SVI_0405	4.015e-14	85.0	28JTM@1|root,2Z9IU@2|Bacteria,1R4C3@1224|Proteobacteria,1S120@1236|Gammaproteobacteria,2QAYM@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_3936683_11	1034769.KB910518_gene5138	5.17e-50	200.0	COG1208@1|root,COG1208@2|Bacteria,1V5SC@1239|Firmicutes,4HI1U@91061|Bacilli,26WPK@186822|Paenibacillaceae	91061|Bacilli	JM	MobA-like NTP transferase domain	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_3936683_8	1123277.KB893206_gene3359	1.512e-66	239.0	COG1577@1|root,COG1577@2|Bacteria,4NH6H@976|Bacteroidetes,47N8V@768503|Cytophagia	976|Bacteroidetes	I	GHMP kinases C terminal	-	-	2.7.1.43	ko:K16190	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014	R01476	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_3936683_5	1038859.AXAU01000008_gene2083	1.266e-133	451.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
CMS3_k127_3936683_0	395964.KE386496_gene3082	1.045e-183	607.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3NA3Z@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_3936683_1	1394178.AWOO02000015_gene7055	2.494e-183	601.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EHHR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_3936683_12	1267535.KB906767_gene4838	2.26e-43	183.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_3936683_14	33876.JNXY01000017_gene7297	6.427e-32	145.0	COG3576@1|root,COG3576@2|Bacteria,2H5HQ@201174|Actinobacteria,4DBHH@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5-phosphate	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_3936683_15	1489678.RDMS_03545	2.473e-23	117.0	COG0563@1|root,COG0563@2|Bacteria,1WMN6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3936683_16	1536773.R70331_20890	2.864e-21	110.0	COG1595@1|root,COG1595@2|Bacteria,1V70Y@1239|Firmicutes,4HINM@91061|Bacilli,26T02@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoD3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF1835,Sigma70_r2,Sigma70_r4_2
CMS3_k127_3936683_20	861299.J421_1361	1.654e-09	72.0	COG0666@1|root,COG0666@2|Bacteria,1ZV8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_4
CMS3_k127_3936683_17	1196323.ALKF01000186_gene5698	2.19e-18	101.0	COG0055@1|root,COG0055@2|Bacteria,1UATS@1239|Firmicutes,4HBRA@91061|Bacilli,26V52@186822|Paenibacillaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	HTH_26
CMS3_k127_3936683_4	247633.GP2143_09795	1.124e-136	463.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS3_k127_3936683_3	247633.GP2143_09790	6.147e-152	529.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_3936683_10	1245475.ANAE01000176_gene5121	8.604e-57	203.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4EIYA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS3_k127_3936683_9	1282876.BAOK01000002_gene513	7.637e-58	208.0	2C6CV@1|root,33TSY@2|Bacteria,1NVBF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_394018_30	661478.OP10G_2900	1.419e-22	102.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528,ko:K20444	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko01005,ko02000,ko03009	4.D.1.3	GT2,GT4	-	CTP_transf_like,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_12,Methyltransf_23,RrnaAD
CMS3_k127_394018_5	1282876.BAOK01000002_gene539	2.449e-158	520.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2TRZV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_394018_29	639030.JHVA01000001_gene2065	2.944e-24	116.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_394018_15	1041159.AZUW01000033_gene2465	2.651e-105	373.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_394018_1	685727.REQ_42910	1.2e-209	677.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4FUZR@85025|Nocardiaceae	201174|Actinobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_394018_20	298654.FraEuI1c_5715	8.108e-66	240.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_394018_6	391625.PPSIR1_06611	4.603e-152	507.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	1.3.1.21,1.3.1.70	ko:K00213,ko:K00222	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101	R01451,R01456,R05639,R07483,R07487,R07492	RC00138,RC01441	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1295,ERG4_ERG24,PEMT,Steroid_dh
CMS3_k127_394018_22	314278.NB231_16408	1.175e-63	240.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,1S87G@1236|Gammaproteobacteria,1X27D@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
CMS3_k127_394018_14	105559.Nwat_0818	5.805e-108	382.0	COG1159@1|root,COG1159@2|Bacteria,1QW17@1224|Proteobacteria,1T2QX@1236|Gammaproteobacteria,1WW85@135613|Chromatiales	135613|Chromatiales	S	GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
CMS3_k127_394018_35	357808.RoseRS_2634	1.138e-05	59.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,376IU@32061|Chloroflexia	32061|Chloroflexia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_394018_21	595460.RRSWK_01941	2.779e-65	251.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_394018_17	1122962.AULH01000009_gene3808	3.395e-87	300.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TSIF@28211|Alphaproteobacteria,370H2@31993|Methylocystaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_394018_27	1298867.AUES01000013_gene5367	5.739e-54	197.0	COG0625@1|root,COG0625@2|Bacteria,1N2Z1@1224|Proteobacteria,2U0AX@28211|Alphaproteobacteria,3JQT5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N,GST_N_3
CMS3_k127_394018_7	378806.STAUR_1357	2.31e-151	494.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2WXF1@28221|Deltaproteobacteria,2YU87@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_394018_13	471852.Tcur_2371	1.236e-108	358.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4EH9H@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_394018_32	1168065.DOK_00055	9.493e-14	80.0	COG1309@1|root,COG1309@2|Bacteria,1NJ8A@1224|Proteobacteria,1SNPK@1236|Gammaproteobacteria,1J7DP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_394018_8	235985.BBPN01000014_gene5539	1.433e-142	473.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,2NEZW@228398|Streptacidiphilus	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.8.1.20	ko:K22347	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
CMS3_k127_394018_31	1219035.NT2_01_06000	3.481e-22	103.0	COG0346@1|root,COG0346@2|Bacteria,1N3QS@1224|Proteobacteria,2V1CP@28211|Alphaproteobacteria,2KBDM@204457|Sphingomonadales	204457|Sphingomonadales	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_394018_10	1078020.KEK_11963	3.777e-125	411.0	28MAM@1|root,2ZAP9@2|Bacteria,2IAHG@201174|Actinobacteria,235G8@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_394018_16	1128421.JAGA01000004_gene2704	7.431e-97	349.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_394018_3	28042.GU90_03950	4.239e-196	627.0	COG1960@1|root,COG1960@2|Bacteria,2GJX5@201174|Actinobacteria,4DZXN@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE12_3	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_394018_9	1278073.MYSTI_04828	1.895e-129	428.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_394018_4	1158182.KB905021_gene380	1.812e-189	606.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS3_k127_394018_26	358220.C380_19995	9.038e-56	207.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,2WEVQ@28216|Betaproteobacteria,4AESC@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_394018_11	247633.GP2143_10057	2.087e-110	383.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RZUZ@1236|Gammaproteobacteria,1J9Y6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_394018_12	402881.Plav_0222	1.723e-109	360.0	COG1024@1|root,COG1024@2|Bacteria,1RA5T@1224|Proteobacteria,2UP3E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_394018_0	1121456.ATVA01000011_gene1437	5.781e-235	739.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2M84Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_394018_2	292459.STH2121	4.996e-202	652.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,25E6C@186801|Clostridia	186801|Clostridia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS3_k127_394018_24	743720.Psefu_2988	6.016e-63	243.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1YV8G@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Sulfatase	mdoB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006490,GO:0006629,GO:0008150,GO:0008152,GO:0008960,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0042597,GO:0044237,GO:0044238,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_394018_25	448385.sce4785	4.759e-56	225.0	COG3568@1|root,COG3568@2|Bacteria,1NJUY@1224|Proteobacteria,432E7@68525|delta/epsilon subdivisions,2WXI5@28221|Deltaproteobacteria,2YVNS@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_394018_33	1267534.KB906754_gene3486	1.798e-11	78.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_394018_19	247633.GP2143_01710	2.421e-80	288.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS3_k127_394018_18	1403819.BATR01000118_gene4111	8.189e-87	321.0	COG3264@1|root,COG3264@2|Bacteria,46T7X@74201|Verrucomicrobia,2IWP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS3_k127_394018_23	575540.Isop_0172	5.878e-63	236.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_394018_28	1047013.AQSP01000106_gene1773	1.938e-48	195.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS3_k127_3950542_1	1121423.JONT01000001_gene2108	4.075e-07	55.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24N7A@186801|Clostridia,262C9@186807|Peptococcaceae	186801|Clostridia	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS3_k127_3950542_0	102129.Lepto7375DRAFT_2788	6.603e-23	117.0	COG3210@1|root,COG4995@1|root,COG3210@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1HF82@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act
CMS3_k127_3969646_8	1123237.Salmuc_00512	4.792e-56	224.0	COG1793@1|root,COG1793@2|Bacteria,1NTIR@1224|Proteobacteria,2VG1E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
CMS3_k127_3969646_7	660470.Theba_0073	2.135e-60	214.0	COG1793@1|root,COG1793@2|Bacteria	2|Bacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
CMS3_k127_3969646_10	1379698.RBG1_1C00001G0629	9.169e-27	119.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
CMS3_k127_3969646_3	29306.JOBE01000010_gene7154	2.3e-93	315.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_primase_S
CMS3_k127_3969646_0	1121459.AQXE01000007_gene611	2.299e-167	566.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2M8C5@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	elongation factor G domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_3969646_5	1155718.KB891880_gene5113	2.53e-78	274.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3969646_2	1461694.ATO9_00105	2.337e-107	374.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2PDTE@252301|Oceanicola	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_3969646_4	883078.HMPREF9695_02101	1.346e-92	311.0	COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2U1AK@28211|Alphaproteobacteria,3JTHH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3969646_6	1122137.AQXF01000003_gene2406	2.295e-74	268.0	COG3917@1|root,COG3917@2|Bacteria,1RA6I@1224|Proteobacteria,2U5JB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	MA20_25040	-	5.99.1.4	ko:K14584	ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220	M00534	R05137	RC03084	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DSBA
CMS3_k127_3969646_1	1382303.JPOM01000001_gene2331	3.505e-119	392.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2KFMY@204458|Caulobacterales	204458|Caulobacterales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_3969646_9	402881.Plav_2129	1.02e-29	126.0	COG1309@1|root,COG1309@2|Bacteria,1N3KN@1224|Proteobacteria,2UI3H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3969646_11	710686.Mycsm_04697	1.89e-06	50.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,234ZI@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_3985940_5	1122921.KB898190_gene1385	6.088e-46	173.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,26RHP@186822|Paenibacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS3_k127_3985940_7	44060.JODL01000005_gene546	1.273e-07	59.0	COG3793@1|root,COG3793@2|Bacteria,2HANB@201174|Actinobacteria	201174|Actinobacteria	P	Tellurite resistance	-	-	-	ko:K05793	-	-	-	-	ko00000	-	-	-	TerB
CMS3_k127_3985940_0	1333998.M2A_2185	2.007e-98	329.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,4BQDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_3985940_3	1168065.DOK_15059	7.561e-67	245.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RS8E@1236|Gammaproteobacteria,1JABB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_3985940_2	926550.CLDAP_28300	7.401e-84	291.0	COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi	200795|Chloroflexi	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
CMS3_k127_3985940_4	479434.Sthe_2500	2.746e-61	229.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi,27XFS@189775|Thermomicrobia	189775|Thermomicrobia	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
CMS3_k127_3985940_6	247156.NFA_42070	8.798e-19	101.0	COG1920@1|root,COG1920@2|Bacteria,2HJNU@201174|Actinobacteria,4FYS3@85025|Nocardiaceae	201174|Actinobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
CMS3_k127_3985940_1	357808.RoseRS_1138	1.813e-86	315.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi,376XW@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM LPPG domain	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
CMS3_k127_4017704_0	1207063.P24_16300	1.809e-303	955.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2JQ67@204441|Rhodospirillales	204441|Rhodospirillales	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
CMS3_k127_4017704_1	1232410.KI421416_gene2699	1.636e-188	605.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2WJJP@28221|Deltaproteobacteria,43UUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sulfate permease family	ychM	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,STAS,STAS_2,Sulfate_transp
CMS3_k127_4017704_2	1173024.KI912148_gene3523	8.18e-173	580.0	COG2403@1|root,COG2403@2|Bacteria,1G1FF@1117|Cyanobacteria	1117|Cyanobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	cobW
CMS3_k127_4017704_13	626887.J057_21115	4.241e-73	277.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the carbamate kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0454,iECED1_1282.ECED1_0540,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iJN746.PP_0999	AA_kinase
CMS3_k127_4017704_19	1313421.JHBV01000043_gene3191	2.916e-30	132.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_4017704_20	366602.Caul_0664	5.846e-29	121.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2UDEK@28211|Alphaproteobacteria,2KGZA@204458|Caulobacterales	204458|Caulobacterales	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CMS3_k127_4017704_23	502025.Hoch_1258	4.662e-16	94.0	28UWD@1|root,2ZH0B@2|Bacteria,1PYHW@1224|Proteobacteria,435D3@68525|delta/epsilon subdivisions,2WZQN@28221|Deltaproteobacteria,2Z2IX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4017704_9	1144275.COCOR_07387	1.627e-96	330.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_4017704_24	1122152.AUEI01000004_gene877	1.182e-06	61.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae	91061|Bacilli	S	Helix-turn-helix domain	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CMS3_k127_4017704_16	1232410.KI421413_gene854	3.492e-58	224.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,43T10@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
CMS3_k127_4017704_5	926560.KE387023_gene1680	1.16e-120	399.0	COG3173@1|root,COG3173@2|Bacteria,1WM3S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_4017704_6	1142394.PSMK_21870	3.649e-114	397.0	COG0659@1|root,COG0659@2|Bacteria,2IY7T@203682|Planctomycetes	203682|Planctomycetes	P	COG0659 Sulfate permease and related transporters (MFS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS3_k127_4017704_4	502025.Hoch_0519	3.417e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4017704_7	502025.Hoch_0520	1.881e-110	367.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,43418@68525|delta/epsilon subdivisions,2X2J1@28221|Deltaproteobacteria,2Z08E@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4017704_18	502025.Hoch_0521	9.919e-46	187.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4017704_10	502025.Hoch_0522	5.292e-92	321.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2WKKE@28221|Deltaproteobacteria,2YXC9@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CMS3_k127_4017704_11	502025.Hoch_0523	8.507e-81	307.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2Z15V@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
CMS3_k127_4017704_17	502025.Hoch_0525	1.571e-55	222.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1Q1X1@1224|Proteobacteria,437J0@68525|delta/epsilon subdivisions,2WYKS@28221|Deltaproteobacteria,2Z2BC@29|Myxococcales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS3_k127_4017704_21	502025.Hoch_0525	1.909e-24	119.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1Q1X1@1224|Proteobacteria,437J0@68525|delta/epsilon subdivisions,2WYKS@28221|Deltaproteobacteria,2Z2BC@29|Myxococcales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS3_k127_4017704_8	404589.Anae109_1825	3.837e-110	388.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_4017704_22	575540.Isop_0179	1.615e-17	98.0	COG2755@1|root,COG2755@2|Bacteria,2J2X7@203682|Planctomycetes	203682|Planctomycetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4017704_14	1122132.AQYH01000010_gene4009	1.62e-61	240.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_4017704_12	498211.CJA_0923	6.012e-79	267.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1FG5N@10|Cellvibrio	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS3_k127_4017704_3	472759.Nhal_3071	5.935e-145	484.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1WWWM@135613|Chromatiales	135613|Chromatiales	O	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_4017704_15	1205680.CAKO01000002_gene2546	8.394e-60	223.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_4029027_14	616991.JPOO01000001_gene3364	1.21e-56	201.0	COG0500@1|root,COG2226@2|Bacteria,4NP7E@976|Bacteroidetes,1I1YN@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_4029027_13	1282876.BAOK01000002_gene507	3.87e-58	221.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria	1224|Proteobacteria	V	Mate efflux family protein	yeeO	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_4029027_12	926560.KE387027_gene366	1.254e-59	234.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_4029027_0	298654.FraEuI1c_4779	1.178e-148	481.0	COG2159@1|root,COG2159@2|Bacteria,2GMRC@201174|Actinobacteria	201174|Actinobacteria	I	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_4029027_7	264198.Reut_B5205	2.861e-83	286.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2VK16@28216|Betaproteobacteria,1K64U@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
CMS3_k127_4029027_2	402881.Plav_0370	1.131e-134	463.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,1JN17@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	PFAM aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_4029027_6	1045009.AFXQ01000009_gene801	2.489e-90	304.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS3_k127_4029027_9	106370.Francci3_3423	4.001e-78	277.0	COG1024@1|root,COG1024@2|Bacteria,2IGUN@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_4029027_15	1121440.AUMA01000009_gene694	4.632e-50	194.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria,2M7UE@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_4029027_8	391625.PPSIR1_07742	4.543e-79	289.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QU3@68525|delta/epsilon subdivisions,2WMTF@28221|Deltaproteobacteria,2YV2S@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4029027_3	391625.PPSIR1_07723	3.689e-113	381.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2WKT1@28221|Deltaproteobacteria,2Z2YB@29|Myxococcales	28221|Deltaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_4029027_4	391625.PPSIR1_07718	1.136e-106	360.0	COG4591@1|root,COG4591@2|Bacteria,1RD9H@1224|Proteobacteria,43AMQ@68525|delta/epsilon subdivisions,2X61T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_4029027_11	1303518.CCALI_00462	9.386e-60	218.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	asnA2	-	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
CMS3_k127_4029027_10	404589.Anae109_0137	1.625e-68	253.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS3_k127_4029027_5	1415780.JPOG01000001_gene2579	6.201e-105	373.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1X4DT@135614|Xanthomonadales	135614|Xanthomonadales	G	Na melibiose symporter and related transporters	ynaJ	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS3_k127_4029027_1	109760.SPPG_08536T0	4.758e-140	484.0	COG2021@1|root,2QR3J@2759|Eukaryota,38CHD@33154|Opisthokonta,3NVHE@4751|Fungi	4751|Fungi	H	homoserine O-acetyltransferase	cys2	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009066,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_4029027_16	1122197.ATWI01000015_gene771	4.459e-12	72.0	COG3009@1|root,COG3009@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	ymbA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0036405,GO:0036406,GO:0042597,GO:0042802,GO:0044425,GO:0044462,GO:0044464,GO:0071944,GO:0098552	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
CMS3_k127_4078740_22	1452718.JBOY01000024_gene346	5.057e-41	157.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	decarboxylase	-	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
CMS3_k127_4078740_21	1280953.HOC_19491	9.12e-45	181.0	COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,2U1TZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS3_k127_4078740_7	472759.Nhal_0141	5.969e-163	538.0	COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,1RP1J@1236|Gammaproteobacteria,1WYBF@135613|Chromatiales	135613|Chromatiales	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
CMS3_k127_4078740_11	1502850.FG91_00432	2.608e-102	349.0	COG0412@1|root,COG0412@2|Bacteria,1PSEB@1224|Proteobacteria,2TTN4@28211|Alphaproteobacteria,2K4IX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_4078740_15	1123023.JIAI01000002_gene4957	8.344e-62	242.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
CMS3_k127_4078740_8	402881.Plav_1795	3.887e-162	533.0	COG2159@1|root,COG2159@2|Bacteria,1PZ2M@1224|Proteobacteria,2VCU0@28211|Alphaproteobacteria,1JQHC@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_4078740_25	502025.Hoch_1656	3.766e-33	137.0	COG1309@1|root,COG1309@2|Bacteria,1N6HV@1224|Proteobacteria,4338G@68525|delta/epsilon subdivisions,2WXPN@28221|Deltaproteobacteria,2YW3D@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS3_k127_4078740_23	1123319.AUBE01000007_gene3476	1.535e-38	154.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.46,1.14.11.55	ko:K10674,ko:K21195	ko00260,ko00440,ko01120,map00260,map00440,map01120	-	R08050,R10724	RC00661,RC01107	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_4078740_28	1121859.KB890759_gene1935	9.466e-12	78.0	COG1309@1|root,COG1309@2|Bacteria,4NTB4@976|Bacteroidetes,47RD7@768503|Cytophagia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_4078740_26	1189612.A33Q_3784	2.074e-22	113.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,47NC5@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_4078740_16	219305.MCAG_03658	4.713e-59	216.0	COG5285@1|root,COG5285@2|Bacteria,2IAZZ@201174|Actinobacteria,4DGJ8@85008|Micromonosporales	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_4078740_19	661478.OP10G_2949	2.928e-52	205.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.18	ko:K00477,ko:K18562	ko00332,ko01130,ko04146,map00332,map01130,map04146	-	R10415,R10735	RC01525,RC03174	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_4078740_17	498848.TaqDRAFT_4878	1.271e-53	216.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4078740_14	196367.JNFG01000009_gene6241	6.705e-62	226.0	2C7KP@1|root,32UAQ@2|Bacteria,1RBGM@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
CMS3_k127_4078740_24	935565.JAEM01000010_gene1956	1.346e-35	145.0	COG2186@1|root,COG2186@2|Bacteria,1N81Z@1224|Proteobacteria,2US7N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS3_k127_4078740_9	644548.SCNU_15704	6.116e-159	515.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4GF9G@85026|Gordoniaceae	201174|Actinobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_4078740_1	1122247.C731_0925	4.742e-236	754.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,2354H@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE22	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4078740_2	1205680.CAKO01000002_gene2293	1.555e-232	734.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,2JRI5@204441|Rhodospirillales	28211|Alphaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.160,1.14.13.22	ko:K03379,ko:K21730	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_2,Pyr_redox_3
CMS3_k127_4078740_3	1198232.CYCME_0571	3.103e-222	731.0	COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,1RNYT@1236|Gammaproteobacteria,4621T@72273|Thiotrichales	72273|Thiotrichales	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	1.2.5.1	ko:K00156	ko00620,map00620	-	R03145	RC00860	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_4078740_4	1380370.JIBA01000013_gene1274	9.367e-204	648.0	COG0069@1|root,COG0069@2|Bacteria,2GME2@201174|Actinobacteria,4FFI8@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the glutamate synthase family	yerD	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS3_k127_4078740_10	234267.Acid_7580	1.17e-106	378.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GJ@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
CMS3_k127_4078740_0	1267535.KB906767_gene5180	2.046e-260	814.0	COG0843@1|root,COG0843@2|Bacteria,3Y37Z@57723|Acidobacteria,2JIKT@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS3_k127_4078740_18	682795.AciX8_2888	9.553e-53	211.0	COG1845@1|root,COG1845@2|Bacteria,3Y4DA@57723|Acidobacteria,2JJ26@204432|Acidobacteriia	204432|Acidobacteriia	C	cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
CMS3_k127_4078740_13	1267535.KB906767_gene5178	8.861e-67	237.0	2C2MA@1|root,2Z87X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4078740_20	234267.Acid_7584	9.45e-52	201.0	COG2010@1|root,COG2010@2|Bacteria,3Y9B6@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Cytochrome c, class I	-	-	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
CMS3_k127_4078740_12	1267535.KB906767_gene5176	1.643e-68	241.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K03886	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00151,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
CMS3_k127_4078740_5	1267535.KB906767_gene5175	1.325e-196	633.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y2JP@57723|Acidobacteria,2JHJQ@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_N_2,Cytochrome_CBB3
CMS3_k127_4078740_6	1267535.KB906767_gene5174	1.386e-174	575.0	COG0348@1|root,COG3336@1|root,COG0348@2|Bacteria,COG3336@2|Bacteria,3Y3CM@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
CMS3_k127_4090902_7	1266925.JHVX01000006_gene2247	7.485e-79	270.0	COG4221@1|root,COG4221@2|Bacteria,1NTNU@1224|Proteobacteria,2WI8R@28216|Betaproteobacteria,373KI@32003|Nitrosomonadales	28216|Betaproteobacteria	S	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4090902_3	298653.Franean1_6359	2.039e-127	419.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_4090902_6	7165.AGAP010368-PA	3.619e-82	295.0	COG0028@1|root,KOG1185@2759|Eukaryota,38EFU@33154|Opisthokonta,3BGF6@33208|Metazoa,3CUC0@33213|Bilateria,41U1N@6656|Arthropoda,3SIE0@50557|Insecta,45017@7147|Diptera,45EPY@7148|Nematocera	33208|Metazoa	EH	Belongs to the TPP enzyme family	HACL1	GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681	-	ko:K12261	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_4090902_22	1191523.MROS_1668	8.302e-29	136.0	2C2F5@1|root,32WND@2|Bacteria	2|Bacteria	-	-	VPA0561	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4090902_5	518766.Rmar_2536	4.054e-83	281.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1FIVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4090902_15	323850.Shew_2659	2.381e-57	216.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RQW0@1236|Gammaproteobacteria,2QBD2@267890|Shewanellaceae	1236|Gammaproteobacteria	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_4090902_14	1499967.BAYZ01000022_gene254	2.249e-59	222.0	COG4591@1|root,COG4591@2|Bacteria,2NQKW@2323|unclassified Bacteria	2|Bacteria	M	MacB-like periplasmic core domain	VPA0558	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS3_k127_4090902_16	1313421.JHBV01000042_gene3352	2.272e-56	209.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,1IWMK@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_4090902_17	748247.AZKH_2966	2.206e-48	185.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1N4HS@1224|Proteobacteria,2VMAM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_17,TPR_7,TPR_8
CMS3_k127_4090902_9	1192034.CAP_1429	8.936e-72	258.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
CMS3_k127_4090902_0	404589.Anae109_0939	1.737e-226	729.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
CMS3_k127_4090902_8	118166.JH976537_gene4181	1.285e-74	284.0	COG1738@1|root,COG1738@2|Bacteria,1G49U@1117|Cyanobacteria,1HEMD@1150|Oscillatoriales	1117|Cyanobacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS3_k127_4090902_2	1394178.AWOO02000016_gene6820	2.395e-180	586.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EFMP@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS3_k127_4090902_4	1382306.JNIM01000001_gene2032	8.638e-117	404.0	COG2272@1|root,COG2272@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS3_k127_4090902_13	1121405.dsmv_2561	9.253e-60	222.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria,2MI8X@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS3_k127_4090902_11	1121405.dsmv_2561	1.137e-61	223.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria,2MI8X@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS3_k127_4090902_12	1205908.AKXW01000108_gene1200	1.169e-61	239.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,1RSQ1@1236|Gammaproteobacteria,1XWGA@135623|Vibrionales	135623|Vibrionales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_4090902_10	1205680.CAKO01000006_gene3175	2.424e-65	237.0	COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,2U1WR@28211|Alphaproteobacteria,2JRST@204441|Rhodospirillales	204441|Rhodospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
CMS3_k127_4090902_25	596151.DesfrDRAFT_2898	3.879e-06	58.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_4090902_1	1009370.ALO_11009	7.129e-196	650.0	COG4805@1|root,COG4805@2|Bacteria,1U50A@1239|Firmicutes,4H6J3@909932|Negativicutes	909932|Negativicutes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS3_k127_4090902_19	383372.Rcas_0208	2.865e-34	153.0	COG1216@1|root,COG1216@2|Bacteria,2G9RD@200795|Chloroflexi	200795|Chloroflexi	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4090902_21	491916.RHECIAT_CH0001239	6.274e-30	136.0	COG0625@1|root,COG0625@2|Bacteria,1N5AI@1224|Proteobacteria,2VF4U@28211|Alphaproteobacteria,4BN7A@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
CMS3_k127_4090902_18	1123400.KB904788_gene199	1.803e-39	156.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M50
CMS3_k127_4090902_20	298386.PBPRA0176	3.465e-34	144.0	COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,1XXJZ@135623|Vibrionales	135623|Vibrionales	S	3D domain protein	DR0488	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4090902_23	290397.Adeh_2819	2.627e-13	79.0	COG1287@1|root,COG1287@2|Bacteria,1NYIS@1224|Proteobacteria,430I0@68525|delta/epsilon subdivisions,2WW3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
CMS3_k127_4091106_10	1519439.JPJG01000034_gene1643	9.192e-58	227.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,2N6FP@216572|Oscillospiraceae	186801|Clostridia	M	UDP-N-acetylenolpyruvoylglucosamine reductase	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS3_k127_4091106_1	1144275.COCOR_06094	1.58e-134	463.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2YTUP@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_4091106_9	1121918.ARWE01000001_gene872	8.532e-58	227.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS3_k127_4091106_4	1121468.AUBR01000006_gene362	8.443e-93	321.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_4091106_0	880072.Desac_0600	3.174e-138	448.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MQC4@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
CMS3_k127_4091106_5	290397.Adeh_3767	3.36e-91	317.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2YXRU@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_4091106_2	378806.STAUR_6267	6.805e-122	409.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_4091106_3	1232410.KI421421_gene3858	8.744e-102	364.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TBV@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PASTA domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
CMS3_k127_4091106_6	292459.STH1201	7.095e-91	309.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS3_k127_4091106_12	1125863.JAFN01000001_gene3337	9.099e-26	112.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS3_k127_4091106_7	502025.Hoch_4049	2.436e-89	311.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2YUVF@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS3_k127_4091106_8	502025.Hoch_3216	3.906e-63	231.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42UM2@68525|delta/epsilon subdivisions,2WR61@28221|Deltaproteobacteria,2YVAU@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_4091106_11	502025.Hoch_3215	5.032e-57	222.0	COG0204@1|root,COG0204@2|Bacteria,1N01J@1224|Proteobacteria,42UM7@68525|delta/epsilon subdivisions,2WQN9@28221|Deltaproteobacteria,2Z3CW@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_4091106_13	324602.Caur_3285	3.837e-19	95.0	COG5394@1|root,COG5394@2|Bacteria,2G77C@200795|Chloroflexi,375VS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM PHA accumulation regulator DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
CMS3_k127_4114051_22	1150599.MPHLEI_24866	4.849e-29	121.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,2362Z@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_4114051_9	1347369.CCAD010000086_gene1751	4.358e-90	316.0	COG1960@1|root,COG1960@2|Bacteria,1UYKW@1239|Firmicutes,4HAK3@91061|Bacilli,1ZDBS@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4114051_26	1042375.AFPL01000045_gene1129	1.441e-16	94.0	COG2030@1|root,COG2030@2|Bacteria,1N43Z@1224|Proteobacteria,1S8MB@1236|Gammaproteobacteria,46BJQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_4114051_25	1243664.CAVL020000025_gene1270	2.447e-19	104.0	COG1545@1|root,COG1545@2|Bacteria,1UBMC@1239|Firmicutes,4IN1P@91061|Bacilli,1ZMJK@1386|Bacillus	91061|Bacilli	S	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
CMS3_k127_4114051_0	575540.Isop_0401	1.028e-253	803.0	COG1032@1|root,COG1032@2|Bacteria,2IY6B@203682|Planctomycetes	203682|Planctomycetes	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
CMS3_k127_4114051_23	1121890.AUDO01000007_gene2560	2.735e-24	118.0	COG4124@1|root,COG4124@2|Bacteria,4NIF5@976|Bacteroidetes,1I0PQ@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
CMS3_k127_4114051_2	378806.STAUR_8346	3.657e-155	506.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X4XD@28221|Deltaproteobacteria,2YZSN@29|Myxococcales	28221|Deltaproteobacteria	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
CMS3_k127_4114051_19	543632.JOJL01000054_gene210	2.698e-41	178.0	COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,2IBPU@201174|Actinobacteria,4DAU6@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,GGDEF,Pkinase
CMS3_k127_4114051_14	1236902.ANAS01000022_gene77	4.784e-63	235.0	2DB71@1|root,2Z7JE@2|Bacteria,2I2SN@201174|Actinobacteria,4EMKV@85012|Streptosporangiales	201174|Actinobacteria	C	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
CMS3_k127_4114051_6	1178825.ALIH01000001_gene2467	6.22e-118	400.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_21,Exo_endo_phos
CMS3_k127_4114051_8	471852.Tcur_3385	9.831e-99	347.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EMUX@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_4114051_21	485913.Krac_2739	5.77e-33	146.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
CMS3_k127_4114051_17	1227352.C173_26157	1.936e-46	189.0	COG1670@1|root,COG1670@2|Bacteria,1V26J@1239|Firmicutes,4HG0M@91061|Bacilli,26VVI@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_4114051_3	247633.GP2143_09450	1.798e-125	415.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,1RR6Y@1236|Gammaproteobacteria,1J7P2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2124 Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_4114051_30	1244869.H261_14120	0.0001006	53.0	COG2030@1|root,COG2030@2|Bacteria,1RD6F@1224|Proteobacteria,2UC91@28211|Alphaproteobacteria,2JUFA@204441|Rhodospirillales	204441|Rhodospirillales	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_4114051_31	1343740.M271_04185	0.0004406	49.0	COG3777@1|root,COG3777@2|Bacteria	2|Bacteria	S	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N
CMS3_k127_4114051_24	76114.ebA5293	5.4e-22	112.0	COG0613@1|root,COG0613@2|Bacteria,1RF04@1224|Proteobacteria,2W16S@28216|Betaproteobacteria,2KYJS@206389|Rhodocyclales	206389|Rhodocyclales	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
CMS3_k127_4114051_20	1123321.KB905816_gene2717	2.621e-34	136.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria	201174|Actinobacteria	EGP	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_4114051_7	1382304.JNIL01000001_gene1433	2.681e-110	387.0	COG0183@1|root,COG0183@2|Bacteria,1TRRD@1239|Firmicutes,4HC91@91061|Bacilli,279A4@186823|Alicyclobacillaceae	91061|Bacilli	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4114051_28	1340434.AXVA01000003_gene2107	1.043e-14	84.0	COG0596@1|root,COG0596@2|Bacteria,1U3F6@1239|Firmicutes,4HFV2@91061|Bacilli,1ZCQM@1386|Bacillus	91061|Bacilli	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4114051_18	1313172.YM304_20180	9.743e-43	175.0	COG0406@1|root,COG0406@2|Bacteria,2GM22@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_4114051_27	1229780.BN381_130123	3.898e-16	82.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_4114051_10	1123279.ATUS01000001_gene2396	3.298e-82	295.0	COG5361@1|root,COG5361@2|Bacteria,1NQYA@1224|Proteobacteria,1SJTP@1236|Gammaproteobacteria,1J97U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
CMS3_k127_4114051_12	1280950.HJO_14382	3.372e-69	259.0	COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,43XNX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,PCMT
CMS3_k127_4114051_13	977880.RALTA_B0515	2.528e-67	239.0	COG1028@1|root,COG1028@2|Bacteria,1P48D@1224|Proteobacteria,2VQPV@28216|Betaproteobacteria,1KFSX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.357	ko:K19811	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
CMS3_k127_4114051_5	926569.ANT_03090	5.338e-120	401.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_4114051_11	247634.GPB2148_3099	6.326e-81	282.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RWHH@1236|Gammaproteobacteria,1JA0A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4114051_29	596152.DesU5LDRAFT_2493	6.724e-10	71.0	2DPHF@1|root,33237@2|Bacteria,1R4GY@1224|Proteobacteria,435JT@68525|delta/epsilon subdivisions,2WZY2@28221|Deltaproteobacteria,2M8FU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
CMS3_k127_4114051_1	1333998.M2A_2572	9.23e-225	742.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TT96@28211|Alphaproteobacteria,4BRVI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_4114051_4	314287.GB2207_00215	3.705e-121	398.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	nadp-dependent	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS3_k127_4114051_15	675635.Psed_1588	5.605e-56	213.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_4114051_16	1415780.JPOG01000001_gene63	5.468e-53	198.0	COG3791@1|root,COG3791@2|Bacteria,1MZTR@1224|Proteobacteria,1S5QB@1236|Gammaproteobacteria,1X8A6@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4118725_6	335543.Sfum_0905	1.98e-22	100.0	COG4143@1|root,COG4143@2|Bacteria,1R4IE@1224|Proteobacteria,42QHK@68525|delta/epsilon subdivisions,2WUK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4118725_4	1123393.KB891326_gene68	9.518e-35	142.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,1KSJT@119069|Hydrogenophilales	119069|Hydrogenophilales	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4118725_0	1313172.YM304_08780	4.855e-173	556.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CMUG@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Protein synonym acyl-CoA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_4118725_2	1502851.FG93_05058	2.436e-64	249.0	COG0421@1|root,COG0421@2|Bacteria,1PD54@1224|Proteobacteria,2V9CT@28211|Alphaproteobacteria,3JYAK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_4118725_7	742738.HMPREF9460_00051	2.828e-20	105.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,269AR@186813|unclassified Clostridiales	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4118725_5	1254432.SCE1572_06990	1.102e-28	132.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42P67@68525|delta/epsilon subdivisions,2WJP7@28221|Deltaproteobacteria,2Z34G@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_4118725_3	1123024.AUII01000033_gene1381	8.551e-60	237.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I5UU@201174|Actinobacteria,4E8TP@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
CMS3_k127_4118725_8	497964.CfE428DRAFT_0681	2.819e-18	101.0	COG2909@1|root,COG3710@1|root,COG2909@2|Bacteria,COG3710@2|Bacteria,46UY3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS3_k127_4118725_1	82654.Pse7367_1114	5.974e-140	454.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1H8KG@1150|Oscillatoriales	1117|Cyanobacteria	M	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_4138679_4	1118054.CAGW01000007_gene3882	7.224e-28	119.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,274V8@186822|Paenibacillaceae	91061|Bacilli	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
CMS3_k127_4138679_2	1499967.BAYZ01000139_gene140	2.556e-79	283.0	COG1680@1|root,COG1680@2|Bacteria,2NPA1@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CMS3_k127_4138679_0	246197.MXAN_1912	3.237e-124	430.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2YU74@29|Myxococcales	28221|Deltaproteobacteria	M	Mur ligase family, catalytic domain	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_4138679_5	1380393.JHVP01000001_gene2564	4.492e-14	78.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
CMS3_k127_4138679_1	1121920.AUAU01000004_gene809	1.039e-101	351.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria	57723|Acidobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_4138679_3	1121377.KB906404_gene2858	3.781e-30	139.0	COG3393@1|root,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,FR47,GNAT_acetyltran
CMS3_k127_4142647_6	926566.Terro_1732	3.733e-09	67.0	COG2244@1|root,COG2244@2|Bacteria,3Y3E3@57723|Acidobacteria,2JIW1@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_4142647_0	626887.J057_20740	6.004e-199	641.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS3_k127_4142647_4	324602.Caur_0192	1.776e-37	156.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4
CMS3_k127_4142647_2	290397.Adeh_2651	1.105e-120	407.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4142647_7	1111454.HMPREF1250_1176	0.0008858	51.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,4H249@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
CMS3_k127_4142647_1	1293054.HSACCH_02440	2.129e-173	567.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1U91N@1239|Firmicutes,24ARB@186801|Clostridia	186801|Clostridia	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
CMS3_k127_4142647_3	656024.FsymDg_1675	1.978e-105	368.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_4142647_5	1086011.HJ01_00330	3.912e-31	129.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,1HZ2J@117743|Flavobacteriia,2NT5W@237|Flavobacterium	976|Bacteroidetes	H	Phenylacetate--CoA ligase	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS3_k127_4174589_6	1121334.KB911072_gene2588	2.705e-41	163.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WGWE@541000|Ruminococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS3_k127_4174589_1	502025.Hoch_6887	6.554e-102	343.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_4174589_8	404589.Anae109_1309	2.788e-29	121.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria,2YVJ6@29|Myxococcales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS3_k127_4174589_12	665942.HMPREF1022_00421	1.999e-17	93.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria,2M91B@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS3_k127_4174589_3	1121918.ARWE01000001_gene3541	1.256e-65	251.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,43SB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS3_k127_4174589_14	1121033.AUCF01000006_gene4158	0.0002423	53.0	COG0810@1|root,COG0810@2|Bacteria,1MZXC@1224|Proteobacteria,2UCBT@28211|Alphaproteobacteria,2JT5F@204441|Rhodospirillales	204441|Rhodospirillales	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_4174589_9	1125863.JAFN01000001_gene1509	8.028e-29	127.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
CMS3_k127_4174589_7	338963.Pcar_2978	3.004e-40	160.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,43S1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
CMS3_k127_4174589_0	1121403.AUCV01000006_gene404	1.021e-110	379.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2MIFW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS3_k127_4174589_13	671143.DAMO_2786	2.003e-09	66.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
CMS3_k127_4174589_2	378806.STAUR_6539	1.407e-79	278.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YU1B@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_4174589_10	671143.DAMO_0006	2.481e-19	95.0	COG1430@1|root,COG1430@2|Bacteria,2NQ88@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS3_k127_4174589_11	243231.GSU1762	3.745e-18	98.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
CMS3_k127_4174589_5	309801.trd_1044	6.045e-49	181.0	COG0521@1|root,COG0521@2|Bacteria,2G6YJ@200795|Chloroflexi,27Y8Y@189775|Thermomicrobia	189775|Thermomicrobia	H	May be involved in the biosynthesis of molybdopterin	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS3_k127_4174589_4	292459.STH3180	6.286e-56	200.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS3_k127_4187841_14	1177181.T9A_00193	3.245e-79	296.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,1S1Y5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_4187841_34	1297617.JPJD01000058_gene989	3.231e-35	157.0	COG0794@1|root,COG0794@2|Bacteria,1TQ04@1239|Firmicutes,249KC@186801|Clostridia,26A12@186813|unclassified Clostridiales	186801|Clostridia	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS
CMS3_k127_4187841_62	797210.Halxa_2109	3.033e-06	59.0	COG0329@1|root,arCOG04172@2157|Archaea,2XSYJ@28890|Euryarchaeota,23TPI@183963|Halobacteria	183963|Halobacteria	E	Dihydrodipicolinate synthase N-acetylneuraminate lyase	dapA2	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS3_k127_4187841_31	1192034.CAP_5016	1.09e-38	154.0	COG0745@1|root,COG0745@2|Bacteria,1NUNK@1224|Proteobacteria,43CMR@68525|delta/epsilon subdivisions,2X7UV@28221|Deltaproteobacteria,2Z3I4@29|Myxococcales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Response_reg
CMS3_k127_4187841_4	1111732.AZOD01000004_gene1018	5.417e-167	535.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1X2YM@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS3_k127_4187841_45	1463921.JODF01000028_gene3454	4.898e-22	103.0	COG1120@1|root,COG1120@2|Bacteria,2I9Y4@201174|Actinobacteria	201174|Actinobacteria	HP	ABC transporter	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS3_k127_4187841_47	1089552.KI911559_gene2088	3.404e-20	106.0	COG4559@1|root,COG4559@2|Bacteria,1RD7N@1224|Proteobacteria,2TTTR@28211|Alphaproteobacteria,2JSB9@204441|Rhodospirillales	204441|Rhodospirillales	P	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system	hmuV	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS3_k127_4187841_18	1121405.dsmv_2493	1.336e-64	246.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42PIH@68525|delta/epsilon subdivisions,2WJH2@28221|Deltaproteobacteria,2MIKZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS3_k127_4187841_35	215803.DB30_8222	9.446e-35	145.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria,2YVK6@29|Myxococcales	28221|Deltaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_4187841_52	1122919.KB905588_gene4039	3.129e-13	78.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,26X94@186822|Paenibacillaceae	91061|Bacilli	L	DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS3_k127_4187841_13	443143.GM18_0685	2.5e-79	279.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,43SCB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_4187841_6	329726.AM1_1733	1.564e-117	391.0	COG0502@1|root,COG0502@2|Bacteria,1G3B8@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.bioB	BATS,Radical_SAM
CMS3_k127_4187841_9	671143.DAMO_1250	5.896e-98	335.0	COG0156@1|root,COG0156@2|Bacteria,2NNMX@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47,6.2.1.14	ko:K00639,ko:K00652,ko:K01906	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03209,R03210,R10124	RC00004,RC00014,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_4187841_29	290397.Adeh_0070	1.031e-41	169.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,2Z324@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS3_k127_4187841_39	269799.Gmet_0102	8.49e-29	122.0	COG3266@1|root,COG3266@2|Bacteria,1N9VA@1224|Proteobacteria,42VXQ@68525|delta/epsilon subdivisions,2WSBF@28221|Deltaproteobacteria,43UX6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4187841_54	933262.AXAM01000010_gene1390	5.758e-13	77.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2MK6Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS3_k127_4187841_2	502025.Hoch_6062	8.787e-223	714.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2YU1A@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_4187841_15	653733.Selin_2248	1.008e-70	251.0	COG0224@1|root,COG0224@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
CMS3_k127_4187841_3	246197.MXAN_7028	6.865e-215	702.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2YUF7@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS3_k127_4187841_49	243231.GSU0109	1.303e-18	100.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,43V2P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS3_k127_4187841_65	1131451.O1K_19286	0.0009135	49.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1X60B@135614|Xanthomonadales	135614|Xanthomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS3_k127_4187841_59	1449126.JQKL01000038_gene962	4.53e-11	72.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia	186801|Clostridia	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_4187841_24	1304880.JAGB01000005_gene2449	4.797e-56	216.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_4187841_10	243231.GSU0106	9.045e-89	310.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,43T9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_4187841_51	1249627.D779_3085	8.535e-16	90.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1WXDT@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS3_k127_4187841_53	1121423.JONT01000003_gene1131	3.147e-13	84.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,260UK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
CMS3_k127_4187841_16	439235.Dalk_4133	4.223e-68	256.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MJ96@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS3_k127_4187841_41	325777.GW15_0210505	1.853e-23	114.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,1X7XD@135614|Xanthomonadales	135614|Xanthomonadales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS3_k127_4187841_57	243231.GSU3468	9.037e-13	73.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,43VN0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS3_k127_4187841_58	889378.Spiaf_0005	5.794e-12	68.0	COG0230@1|root,COG0230@2|Bacteria,2J8S9@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS3_k127_4187841_8	338963.Pcar_0002	1.353e-98	345.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,43T1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS3_k127_4187841_1	234267.Acid_0003	1.411e-244	781.0	COG0187@1|root,COG0187@2|Bacteria,3Y369@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS3_k127_4187841_0	1408254.T458_26210	1.532e-294	927.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,26SZ3@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS3_k127_4187841_5	321327.CYA_2386	4.476e-165	532.0	COG0001@1|root,COG0001@2|Bacteria,1G162@1117|Cyanobacteria,1GYKV@1129|Synechococcus	1117|Cyanobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_4187841_37	289376.THEYE_A1530	2.261e-31	139.0	COG0356@1|root,COG0356@2|Bacteria,3J0RW@40117|Nitrospirae	40117|Nitrospirae	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS3_k127_4187841_60	1379858.N508_01616	6.118e-10	65.0	COG0636@1|root,COG0636@2|Bacteria,2GFX7@200930|Deferribacteres	200930|Deferribacteres	P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS3_k127_4187841_25	880072.Desac_0007	1.719e-49	183.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS3_k127_4187841_23	1122963.AUHB01000003_gene4133	1.894e-57	204.0	COG1335@1|root,COG1335@2|Bacteria,1MYT8@1224|Proteobacteria,2UE0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	isochorismatase, hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS3_k127_4187841_50	745310.G432_18505	1.384e-16	93.0	COG0662@1|root,COG0662@2|Bacteria,1NK4A@1224|Proteobacteria	1224|Proteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_4187841_63	1129794.C427_0142	5.707e-05	55.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S8IP@1236|Gammaproteobacteria,467J8@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23
CMS3_k127_4187841_19	1027273.GZ77_15335	7.868e-62	217.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4743,NUDIX
CMS3_k127_4187841_46	1236542.BALM01000008_gene2893	5.831e-22	104.0	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,1SCDT@1236|Gammaproteobacteria,2QCGD@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4187841_55	566466.NOR53_1824	5.985e-13	74.0	2DVHZ@1|root,33W03@2|Bacteria,1NX3H@1224|Proteobacteria,1SP80@1236|Gammaproteobacteria,1JAEC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
CMS3_k127_4187841_42	247634.GPB2148_230	2.466e-23	109.0	COG1309@1|root,COG1309@2|Bacteria,1PIS9@1224|Proteobacteria,1SFRX@1236|Gammaproteobacteria,1J6YQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4187841_7	1254432.SCE1572_45270	4.719e-116	387.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_4187841_36	1157490.EL26_22190	1.808e-34	153.0	COG1011@1|root,COG1011@2|Bacteria,1VDD7@1239|Firmicutes,4ISJ7@91061|Bacilli	91061|Bacilli	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS3_k127_4187841_48	62928.azo2848	1.877e-19	95.0	COG2105@1|root,COG2105@2|Bacteria,1NEI1@1224|Proteobacteria,2W3FC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS3_k127_4187841_26	1120949.KB903328_gene8777	1.757e-47	183.0	COG3178@1|root,COG3178@2|Bacteria,2GNRB@201174|Actinobacteria,4DD76@85008|Micromonosporales	201174|Actinobacteria	S	'Phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_4187841_33	926560.KE387023_gene2058	2.2e-35	140.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_4187841_27	670292.JH26_22525	7.013e-46	190.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2U67J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_4187841_11	331869.BAL199_15167	1.133e-86	291.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,2TV0I@28211|Alphaproteobacteria,4BRXP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS3_k127_4187841_12	749222.Nitsa_2002	4.128e-86	307.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,42MV8@68525|delta/epsilon subdivisions,2YMAE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS3_k127_4187841_44	1121946.AUAX01000003_gene1830	4.135e-22	103.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4DE4S@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_4187841_43	983917.RGE_19350	8.683e-23	105.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS3_k127_4187841_38	1123322.KB904659_gene1027	5.384e-29	132.0	COG3871@1|root,COG3871@2|Bacteria,2GWY2@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_4187841_28	1380390.JIAT01000011_gene2465	2.178e-43	162.0	COG3791@1|root,COG3791@2|Bacteria,2HQXY@201174|Actinobacteria,4CSQD@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_4187841_32	1120950.KB892780_gene392	8.181e-38	156.0	COG0346@1|root,COG0346@2|Bacteria,2IM78@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4187841_20	290397.Adeh_3502	1.255e-60	221.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,42TB9@68525|delta/epsilon subdivisions,2WXEF@28221|Deltaproteobacteria,2YW3Y@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_4187841_21	1122604.JONR01000025_gene4607	1.226e-59	210.0	COG3791@1|root,COG3791@2|Bacteria,1N3P3@1224|Proteobacteria,1S57G@1236|Gammaproteobacteria,1X8YJ@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_4187841_30	1502852.FG94_02005	2.849e-39	164.0	COG3791@1|root,COG3791@2|Bacteria,1N6S5@1224|Proteobacteria,2WA8G@28216|Betaproteobacteria,4755A@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_4187841_61	591167.Sfla_5732	3.857e-07	62.0	COG1670@1|root,COG1670@2|Bacteria,2IFCT@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS3_k127_4187841_56	391596.PBAL39_08646	7.469e-13	82.0	COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,1IV0H@117747|Sphingobacteriia	976|Bacteroidetes	S	C terminal of Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4985,GHL10,Metallophos,MetallophosC,MetallophosN
CMS3_k127_4187841_22	1230476.C207_06276	1.293e-57	218.0	COG2518@1|root,COG2518@2|Bacteria,1RAIE@1224|Proteobacteria,2U6D7@28211|Alphaproteobacteria,3JUZU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm1	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_4187841_40	207954.MED92_03453	5.439e-24	110.0	COG0346@1|root,COG0346@2|Bacteria,1N810@1224|Proteobacteria,1SVE8@1236|Gammaproteobacteria,1XQFB@135619|Oceanospirillales	135619|Oceanospirillales	C	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4187841_17	744985.HIMB59_00011510	2.248e-67	239.0	COG3491@1|root,COG3491@2|Bacteria,1R7CS@1224|Proteobacteria,2TUIU@28211|Alphaproteobacteria,4BTCI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CMS3_k127_419521_17	258533.BN977_03835	0.0006514	49.0	COG3688@1|root,COG3688@2|Bacteria,2HS1T@201174|Actinobacteria,23A4M@1762|Mycobacteriaceae	201174|Actinobacteria	S	YacP-like NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
CMS3_k127_419521_3	1265313.HRUBRA_01287	1.715e-102	343.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RMGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CH	Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively	ghrB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008873,GO:0008875,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0019520,GO:0019522,GO:0019752,GO:0030267,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046181,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.215,1.1.1.43,1.1.1.79,1.1.1.81,1.20.1.1	ko:K00032,ko:K00090,ko:K18916	ko00030,ko00260,ko00480,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00480,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R01739,R02032,R02034	RC00001,RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_3534	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_419521_2	1198232.CYCME_2122	1.008e-102	370.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_419521_12	404589.Anae109_2327	9.239e-22	111.0	COG3506@1|root,COG5276@1|root,COG3506@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
CMS3_k127_419521_7	1121918.ARWE01000001_gene2578	7.628e-58	232.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,42RV7@68525|delta/epsilon subdivisions,2WNZT@28221|Deltaproteobacteria,43RZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Kinase/pyrophosphorylase	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
CMS3_k127_419521_0	717605.Theco_2421	0.0	1073.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26QCH@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS3_k127_419521_6	1205680.CAKO01000030_gene4799	1.364e-68	248.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,2JPAB@204441|Rhodospirillales	204441|Rhodospirillales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS3_k127_419521_11	240015.ACP_1740	3.287e-30	133.0	COG2121@1|root,COG2121@2|Bacteria,3Y4VJ@57723|Acidobacteria,2JJE4@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
CMS3_k127_419521_5	1121937.AUHJ01000001_gene775	3.93e-87	319.0	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,1RQTP@1236|Gammaproteobacteria,46CIC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_419521_9	489825.LYNGBM3L_55890	1.751e-38	152.0	COG1309@1|root,COG1309@2|Bacteria,1G7IZ@1117|Cyanobacteria,1HHQU@1150|Oscillatoriales	1117|Cyanobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
CMS3_k127_419521_10	1288494.EBAPG3_3000	2.233e-32	137.0	2EFX2@1|root,339PA@2|Bacteria,1NGKD@1224|Proteobacteria,2VY14@28216|Betaproteobacteria,374HM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS3_k127_419521_1	443144.GM21_1703	1.398e-155	519.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,43UG1@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	TIGRFAM phosphoenolpyruvate-protein phosphotransferase	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS3_k127_419521_14	243231.GSU2033	5.94e-10	66.0	COG1476@1|root,COG1476@2|Bacteria,1NB6T@1224|Proteobacteria,42VWK@68525|delta/epsilon subdivisions,2WRMY@28221|Deltaproteobacteria,43VV4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS3_k127_419521_15	398767.Glov_2612	7.893e-09	70.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_1,AsmA_2,Beta_helix,CBM_4_9,DUF3971,DUF748,PKD
CMS3_k127_419521_8	204669.Acid345_3788	9.632e-42	167.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,3Y5F4@57723|Acidobacteria,2JP3J@204432|Acidobacteriia	204432|Acidobacteriia	H	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
CMS3_k127_419521_4	644968.DFW101_1662	9.562e-99	334.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2M840@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4208911_20	1392838.AWNM01000070_gene1234	1.9e-30	127.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,3T39E@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA_2	-	-	ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	HlyD_D23
CMS3_k127_4208911_0	1379698.RBG1_1C00001G1725	2.012e-269	864.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
CMS3_k127_4208911_18	644966.Tmar_1040	3.132e-40	173.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WCHZ@538999|Clostridiales incertae sedis	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS3_k127_4208911_2	1229780.BN381_290013	2.001e-158	516.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	2|Bacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_4208911_15	1121952.ATXT01000018_gene1892	5.03e-57	225.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4FPIM@85023|Microbacteriaceae	201174|Actinobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	apbA_1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS3_k127_4208911_6	6669.EFX72206	1.331e-105	376.0	2CCFM@1|root,2S042@2759|Eukaryota,3AM5W@33154|Opisthokonta,3C0BK@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4208911_7	869210.Marky_0500	1.469e-94	344.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_4208911_3	1121861.KB899944_gene3892	5.003e-142	481.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_4208911_11	1120950.KB892768_gene5306	4.926e-73	270.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,4DWQP@85009|Propionibacteriales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_4208911_16	65497.JODV01000009_gene2861	1.538e-49	200.0	COG0842@1|root,COG0842@2|Bacteria,2I0HP@201174|Actinobacteria,4E1P2@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_4208911_22	882083.SacmaDRAFT_2729	7.232e-26	124.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,4E1XJ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS3_k127_4208911_9	1125971.ASJB01000099_gene2288	1.554e-92	318.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4E1YQ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_4208911_5	1123279.ATUS01000001_gene2395	2.619e-117	397.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4208911_8	448385.sce0767	5.234e-93	315.0	COG1305@1|root,COG1305@2|Bacteria,1R9WH@1224|Proteobacteria	1224|Proteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_4208911_13	909663.KI867150_gene813	3.325e-61	229.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2MQXV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_4208911_19	156889.Mmc1_2934	8.91e-40	163.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.3.1.1	ko:K00537,ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,ArsC,C_GCAxxG_C_C
CMS3_k127_4208911_10	100226.SCO3823	1.047e-89	316.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria	201174|Actinobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_4208911_17	1121456.ATVA01000016_gene2155	5.527e-45	183.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2MBKB@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS3_k127_4208911_12	1415779.JOMH01000001_gene1841	2.048e-72	272.0	COG0664@1|root,COG1033@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1X3P5@135614|Xanthomonadales	135614|Xanthomonadales	T	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	-	-	-	-	-	-	-	-	-	MMPL,cNMP_binding
CMS3_k127_4208911_23	158190.SpiGrapes_2239	4.559e-17	92.0	COG2834@1|root,COG2834@2|Bacteria,2JBH0@203691|Spirochaetes	203691|Spirochaetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_4208911_14	479433.Caci_7935	1.605e-57	222.0	COG1024@1|root,COG1024@2|Bacteria,2I7QX@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_4208911_4	56780.SYN_00437	6.629e-123	412.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MQ7W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS3_k127_4208911_1	1278073.MYSTI_06189	8.642e-172	547.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS3_k127_4208911_24	706587.Desti_4712	5.162e-08	62.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2MSFJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS3_k127_429493_3	187272.Mlg_0300	5.175e-27	122.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1WZSA@135613|Chromatiales	135613|Chromatiales	O	cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS3_k127_429493_0	235985.BBPN01000033_gene11	7.915e-68	248.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,2NH2E@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_429493_4	1122605.KB893645_gene1160	6.56e-22	104.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes	976|Bacteroidetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_429493_2	243090.RB7745	1.451e-63	250.0	COG4625@1|root,COG4625@2|Bacteria,2J2WV@203682|Planctomycetes	203682|Planctomycetes	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
CMS3_k127_429493_1	247633.GP2143_17911	1.373e-66	240.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_429493_5	1121033.AUCF01000026_gene2960	8.652e-14	78.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2U9QU@28211|Alphaproteobacteria,2JRSK@204441|Rhodospirillales	204441|Rhodospirillales	EH	Aminotransferase	-	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_4302185_5	1041930.Mtc_2111	0.0004363	53.0	COG0177@1|root,arCOG00459@2157|Archaea,2XZIZ@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4302185_1	204669.Acid345_4187	5.241e-122	403.0	COG3288@1|root,COG3288@2|Bacteria,3Y2S0@57723|Acidobacteria,2JM52@204432|Acidobacteriia	204432|Acidobacteriia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_4302185_3	1121406.JAEX01000007_gene2380	6.423e-25	121.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,42WKN@68525|delta/epsilon subdivisions,2WRXH@28221|Deltaproteobacteria,2MCPQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
CMS3_k127_4302185_0	864702.OsccyDRAFT_0323	8.912e-148	486.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1H8G7@1150|Oscillatoriales	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS3_k127_4302185_4	1211815.CBYP010000056_gene3324	8.535e-10	72.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4ESUX@85013|Frankiales	201174|Actinobacteria	NU	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_4302185_2	380358.XALC_2409	4.107e-34	154.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1XCB1@135614|Xanthomonadales	1236|Gammaproteobacteria	M	Location of gene products go 0005575	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Peptidase_C39,RHS,RHS_repeat
CMS3_k127_4318013_4	574376.BAMA_20365	6.607e-39	154.0	COG4427@1|root,COG4427@2|Bacteria,1TZ5M@1239|Firmicutes,4HAQV@91061|Bacilli,1ZCQX@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
CMS3_k127_4318013_0	502025.Hoch_4956	5.524e-147	473.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2YU7R@29|Myxococcales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS3_k127_4318013_2	483219.LILAB_33510	1.582e-55	203.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2YVHB@29|Myxococcales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS3_k127_4318013_7	596154.Alide2_3820	7.922e-19	100.0	COG3474@1|root,COG3474@2|Bacteria,1RJS5@1224|Proteobacteria,2WEPN@28216|Betaproteobacteria,4AEMS@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS3_k127_4318013_3	1142394.PSMK_01080	7.031e-52	199.0	28HYD@1|root,2Z83U@2|Bacteria	2|Bacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4318013_6	1122180.Lokhon_00093	4.89e-21	105.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_4318013_5	443143.GM18_0810	2.973e-33	148.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,43RY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_4318013_1	573370.DMR_16010	2.464e-118	387.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2M9GX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_4324471_13	543728.Vapar_2269	1.907e-11	73.0	COG1558@1|root,COG1558@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS3_k127_4324471_14	370438.PTH_2092	4.09e-11	76.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,24RBE@186801|Clostridia,262TE@186807|Peptococcaceae	186801|Clostridia	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
CMS3_k127_4324471_3	1121935.AQXX01000117_gene5115	1.57e-112	386.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XIS3@135619|Oceanospirillales	135619|Oceanospirillales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
CMS3_k127_4324471_9	1101195.Meth11DRAFT_1130	8.947e-34	140.0	COG2063@1|root,COG2063@2|Bacteria,1N7EW@1224|Proteobacteria,2WFQ3@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	-	-	-	-	-	-	-	-	-	FlgH
CMS3_k127_4324471_12	543728.Vapar_2265	3.173e-18	96.0	COG1261@1|root,COG1261@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	flgA	-	-	ko:K02279,ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	ChapFlgA
CMS3_k127_4324471_6	1101195.Meth11DRAFT_1129	4.218e-71	259.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria,2KKBI@206350|Nitrosomonadales	28216|Betaproteobacteria	N	flagellar basal-body rod protein FlgG	-	-	-	-	-	-	-	-	-	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS3_k127_4324471_8	1458357.BG58_41075	1.277e-38	157.0	COG4786@1|root,COG4786@2|Bacteria,1N4D4@1224|Proteobacteria	1224|Proteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bbr_C
CMS3_k127_4324471_0	349521.HCH_04087	1.653e-222	737.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XH92@135619|Oceanospirillales	135619|Oceanospirillales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
CMS3_k127_4324471_4	1101195.Meth11DRAFT_1124	2.201e-85	295.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria,2KMIP@206350|Nitrosomonadales	28216|Betaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	hrcU	-	-	ko:K02401,ko:K03229,ko:K22510	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_2
CMS3_k127_4324471_7	903818.KI912268_gene3436	4.77e-44	171.0	COG1684@1|root,COG1684@2|Bacteria,3Y56U@57723|Acidobacteria	57723|Acidobacteria	NU	Bacterial export proteins, family 1	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
CMS3_k127_4324471_10	1101195.Meth11DRAFT_1122	1.844e-20	94.0	COG1987@1|root,COG1987@2|Bacteria	2|Bacteria	N	bacterial-type flagellum assembly	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
CMS3_k127_4324471_1	1121920.AUAU01000017_gene1239	5.774e-169	553.0	COG0281@1|root,COG0281@2|Bacteria,3Y43V@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
CMS3_k127_4324471_5	472759.Nhal_1345	4.829e-80	302.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X1AV@135613|Chromatiales	135613|Chromatiales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS3_k127_4324471_11	323848.Nmul_D2827	6.072e-20	104.0	2EQGA@1|root,33I2B@2|Bacteria,1NJF5@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4324471_2	1116369.KB890024_gene1369	1.043e-117	385.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,43R7H@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	tsaA	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
CMS3_k127_4344362_2	1282876.BAOK01000001_gene2019	1.31e-94	324.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1062 Zn-dependent alcohol dehydrogenases, class III	MA20_19250	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_4344362_3	1303518.CCALI_00702	3.017e-91	309.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_4344362_4	392500.Swoo_4494	6.257e-56	212.0	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria,2QBUK@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
CMS3_k127_4344362_1	1123279.ATUS01000001_gene1710	6.696e-98	334.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,1S0RF@1236|Gammaproteobacteria,1JAUX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4344362_0	305700.B447_19409	3.65e-121	413.0	COG0446@1|root,COG0446@2|Bacteria,1QXK6@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4344362_5	1168065.DOK_06979	9.154e-44	162.0	COG5361@1|root,COG5361@2|Bacteria,1R4D9@1224|Proteobacteria,1S116@1236|Gammaproteobacteria,1J905@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4346721_12	469371.Tbis_2881	1.523e-131	449.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4DY1G@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_4346721_39	1120934.KB894437_gene4521	4.774e-24	117.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria,4E0EN@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS3_k127_4346721_20	234267.Acid_4736	7.996e-90	316.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_4346721_9	1386969.AWTB01000100_gene3501	1e-147	528.0	COG0183@1|root,COG0183@2|Bacteria,2IDAP@201174|Actinobacteria,4GFM7@85026|Gordoniaceae	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4346721_6	573413.Spirs_4003	3.22e-176	575.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
CMS3_k127_4346721_2	1480694.DC28_14620	3.383e-252	794.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS3_k127_4346721_37	1125863.JAFN01000001_gene2644	4.163e-27	124.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,42M1U@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM PfkB domain protein	-	-	2.7.1.15,2.7.1.4	ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_4346721_45	399739.Pmen_2221	7.401e-09	67.0	2C39R@1|root,32UYY@2|Bacteria,1NMIM@1224|Proteobacteria,1T0KC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4346721_19	1122604.JONR01000016_gene4468	2.198e-96	332.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1X35S@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
CMS3_k127_4346721_36	1123257.AUFV01000013_gene2869	8.557e-34	149.0	COG3219@1|root,COG3219@2|Bacteria,1MZS2@1224|Proteobacteria,1S9N6@1236|Gammaproteobacteria,1X95I@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
CMS3_k127_4346721_10	391625.PPSIR1_32512	2.07e-140	456.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS3_k127_4346721_22	1380391.JIAS01000017_gene634	6.937e-68	241.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,2TSPG@28211|Alphaproteobacteria,2JRPX@204441|Rhodospirillales	204441|Rhodospirillales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS3_k127_4346721_4	926569.ANT_05220	1.027e-213	694.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_4346721_50	1254432.SCE1572_03150	0.0001423	54.0	COG1807@1|root,COG1807@2|Bacteria,1RJ20@1224|Proteobacteria	1224|Proteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4346721_7	1026882.MAMP_01780	1.333e-163	522.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,460E7@72273|Thiotrichales	72273|Thiotrichales	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_4346721_24	1248916.ANFY01000004_gene1854	5.31e-63	222.0	COG0625@1|root,COG0625@2|Bacteria,1RD4X@1224|Proteobacteria,2U63J@28211|Alphaproteobacteria,2KD19@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
CMS3_k127_4346721_42	561175.KB894093_gene3965	6.431e-16	91.0	COG1196@1|root,COG1196@2|Bacteria,2HVYZ@201174|Actinobacteria	201174|Actinobacteria	D	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_4346721_18	1121438.JNJA01000014_gene535	2.117e-96	331.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,42UH9@68525|delta/epsilon subdivisions,2WQRP@28221|Deltaproteobacteria,2MCJ7@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
CMS3_k127_4346721_25	290397.Adeh_2250	6.768e-63	228.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigM	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
CMS3_k127_4346721_48	1157708.KB907450_gene5914	2.008e-07	63.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VKE9@28216|Betaproteobacteria,4AD1Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS3_k127_4346721_46	509190.Cseg_3828	1.849e-08	65.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_4346721_17	1449976.KALB_8096	3.305e-98	351.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DXVN@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4346721_40	384765.SIAM614_05271	2.983e-19	93.0	COG3795@1|root,COG3795@2|Bacteria,1RJIJ@1224|Proteobacteria,2U967@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM YCII-related	MA20_04110	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_4346721_26	391625.PPSIR1_27733	7.068e-62	222.0	2DBMF@1|root,2Z9YG@2|Bacteria,1NUI3@1224|Proteobacteria,434T7@68525|delta/epsilon subdivisions,2X90F@28221|Deltaproteobacteria,2Z1AD@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4346721_14	1229780.BN381_250119	1.333e-124	428.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_4346721_44	1452718.JBOY01000004_gene3094	1.209e-11	78.0	2ED7U@1|root,3374E@2|Bacteria,1NG30@1224|Proteobacteria,1SDDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4346721_21	391625.PPSIR1_01417	8.04e-71	259.0	COG2334@1|root,COG2334@2|Bacteria,1Q18Y@1224|Proteobacteria,42PIW@68525|delta/epsilon subdivisions,2WK5A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_4346721_29	762376.AXYL_05802	1.279e-50	189.0	COG0596@1|root,COG0596@2|Bacteria,1PGVG@1224|Proteobacteria,2W441@28216|Betaproteobacteria,3T6QA@506|Alcaligenaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4346721_16	1282876.BAOK01000001_gene1844	1.046e-101	338.0	COG0491@1|root,COG0491@2|Bacteria,1N22F@1224|Proteobacteria,2U2V5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4346721_41	330214.NIDE0866	7.434e-19	100.0	COG2854@1|root,COG2854@2|Bacteria,3J13Z@40117|Nitrospirae	40117|Nitrospirae	Q	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS3_k127_4346721_34	1121116.KB894766_gene154	4.408e-44	172.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,4ADJ3@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CMS3_k127_4346721_38	1286093.C266_22213	1.496e-24	118.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1K3MD@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_4346721_27	396588.Tgr7_0738	6.505e-59	225.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1WWID@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_4346721_28	1268622.AVS7_02883	2.281e-56	218.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,4A9UN@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM ABC transporter related	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_4346721_35	1089546.AQUI01000002_gene245	3.6e-36	156.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_4346721_5	685727.REQ_10980	2.745e-199	642.0	COG0326@1|root,COG0326@2|Bacteria,2GNPQ@201174|Actinobacteria,4FV89@85025|Nocardiaceae	201174|Actinobacteria	O	Molecular chaperone. Has ATPase activity	htpG	GO:0000302,GO:0000303,GO:0000305,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0010035,GO:0016020,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS3_k127_4346721_0	208444.JNYY01000025_gene5967	0.0	1494.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4DYUS@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_4346721_33	187272.Mlg_2394	8.198e-45	190.0	COG2304@1|root,COG2304@2|Bacteria,1P8UT@1224|Proteobacteria	1224|Proteobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_4346721_43	43759.JNWK01000066_gene4133	2.658e-15	86.0	COG2062@1|root,COG2062@2|Bacteria,2IFF3@201174|Actinobacteria	201174|Actinobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS3_k127_4346721_1	483219.LILAB_34355	3.308e-276	882.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria	1224|Proteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4346721_31	402881.Plav_0854	1.317e-48	190.0	COG0477@1|root,COG2814@2|Bacteria,1RAYJ@1224|Proteobacteria,2U582@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS3_k127_4346721_32	864051.BurJ1DRAFT_1621	2.9e-46	174.0	COG0406@1|root,COG0406@2|Bacteria,1N83T@1224|Proteobacteria,2VY3M@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_4346721_47	29540.C481_17875	1.419e-07	63.0	COG0596@1|root,arCOG01648@2157|Archaea,2XUNG@28890|Euryarchaeota,23SVU@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4346721_49	402881.Plav_2508	5.975e-07	61.0	COG3832@1|root,COG3832@2|Bacteria,1RJC5@1224|Proteobacteria,2UB86@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_4346721_30	1142394.PSMK_08700	7.117e-50	205.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1
CMS3_k127_4346721_23	862908.BMS_2802	9.435e-67	238.0	COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria,42YBC@68525|delta/epsilon subdivisions,2MSW8@213481|Bdellovibrionales,2WUEA@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4346721_13	316057.RPD_3606	2.938e-128	422.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,2TT9T@28211|Alphaproteobacteria,3JTG7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_06725	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_4346721_8	1333998.M2A_1693	9.954e-151	488.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,4BT82@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4346721_15	1297742.A176_07032	1.614e-110	377.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42MT3@68525|delta/epsilon subdivisions,2WIK5@28221|Deltaproteobacteria,2YXG0@29|Myxococcales	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,HI0933_like,Pyr_redox_2
CMS3_k127_4346721_3	106370.Francci3_0938	7.212e-218	696.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4ES07@85013|Frankiales	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS3_k127_4346721_11	1121918.ARWE01000001_gene2746	3.423e-135	446.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,43SCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS3_k127_4383663_7	525368.HMPREF0591_2366	2.554e-146	475.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,233NX@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS3_k127_4383663_27	931627.MycrhDRAFT_2236	2.297e-22	109.0	COG1309@1|root,COG1309@2|Bacteria,2IN4C@201174|Actinobacteria,23A0N@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4383663_11	298655.KI912266_gene5039	2.881e-108	374.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_4383663_4	1242864.D187_009288	4.263e-219	721.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_4383663_26	460265.Mnod_1365	3.553e-25	124.0	COG2267@1|root,COG2267@2|Bacteria,1N8UK@1224|Proteobacteria,2U35V@28211|Alphaproteobacteria,1JX1T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_4383663_23	886293.Sinac_1018	3.29e-35	147.0	COG0500@1|root,COG0500@2|Bacteria,2J1HV@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_4383663_0	1232410.KI421425_gene1552	0.0	1755.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS3_k127_4383663_1	1385517.N800_13180	0.0	1680.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS3_k127_4383663_13	1232410.KI421425_gene1543	5.605e-94	325.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,43SUP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS3_k127_4383663_21	1232410.KI421425_gene1544	6.246e-45	176.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,43V5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_4383663_19	1232410.KI421425_gene1545	2.313e-54	206.0	COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,43UYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_4383663_14	1232410.KI421425_gene1546	1.787e-85	289.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,43TGA@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_4383663_28	1232410.KI421425_gene1547	1.189e-17	91.0	2EQ5T@1|root,32ZV0@2|Bacteria,1NFTI@1224|Proteobacteria,433CK@68525|delta/epsilon subdivisions,2WXC2@28221|Deltaproteobacteria,43VWA@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4383663_20	1232410.KI421425_gene1548	4.522e-45	170.0	COG0457@1|root,COG0457@2|Bacteria,1N1J2@1224|Proteobacteria,42ZHG@68525|delta/epsilon subdivisions,2WV2W@28221|Deltaproteobacteria,43UR6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4383663_2	1232410.KI421425_gene1549	3.897e-318	1032.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,43CT2@68525|delta/epsilon subdivisions,2X80K@28221|Deltaproteobacteria,43TUA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS3_k127_4383663_5	1232410.KI421425_gene1550	8.804e-205	655.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,42Z0Q@68525|delta/epsilon subdivisions,2WU0G@28221|Deltaproteobacteria,43T6R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4383663_22	1385517.N800_13135	8.766e-43	170.0	2B4XH@1|root,32REP@2|Bacteria,1RJ9F@1224|Proteobacteria,1T0SV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4383663_24	378806.STAUR_3528	2.9e-27	120.0	COG0457@1|root,COG0457@2|Bacteria	378806.STAUR_3528|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4383663_25	398767.Glov_1813	1.155e-25	117.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS3_k127_4383663_6	1499686.BN1079_01873	4.774e-201	641.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	aidB	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
CMS3_k127_4383663_30	1048983.EL17_03630	3.626e-10	74.0	COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,47Y4H@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS3_k127_4383663_18	247633.GP2143_17221	1.502e-54	201.0	COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,1S9T2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_4383663_3	1469245.JFBG01000086_gene1608	9.442e-303	970.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,1RN40@1236|Gammaproteobacteria,1X2WW@135613|Chromatiales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	yagR	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_4383663_15	571166.KI421509_gene842	8.079e-76	258.0	COG2080@1|root,COG2080@2|Bacteria,1RB3F@1224|Proteobacteria,2VF0C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_4383663_12	1230476.C207_00510	3.213e-94	317.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria,3JSJE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	xdhB	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_4383663_17	1120936.KB907226_gene2797	2.894e-55	218.0	COG4689@1|root,COG4689@2|Bacteria,2GJWN@201174|Actinobacteria,4EI2S@85012|Streptosporangiales	201174|Actinobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
CMS3_k127_4383663_9	1333998.M2A_2400	7.875e-126	413.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TVBB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4383663_8	402881.Plav_2205	2.439e-145	477.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_22780	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4383663_16	1313172.YM304_41020	1.065e-71	253.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4CNUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_4383663_10	1121949.AQXT01000002_gene1385	3.265e-110	364.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria,43Y1C@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_4383663_29	470.IX87_15175	8.065e-11	72.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,3NM9J@468|Moraxellaceae	1236|Gammaproteobacteria	GM	Outer membrane lipoprotein-sorting protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL,Polyketide_cyc2
CMS3_k127_4435924_3	743719.PaelaDRAFT_4620	4.309e-103	342.0	COG5285@1|root,COG5285@2|Bacteria,1UZS3@1239|Firmicutes,4HA3M@91061|Bacilli,26SQW@186822|Paenibacillaceae	91061|Bacilli	Q	Phytanoyl-CoA dioxygenase (PhyH)	ectD	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_4435924_8	58123.JOFJ01000001_gene2913	1.398e-33	143.0	COG0454@1|root,COG0456@2|Bacteria,2IMKZ@201174|Actinobacteria,4EPAB@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	ectA	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_4435924_2	1283300.ATXB01000001_gene1196	2.399e-111	372.0	COG1638@1|root,COG1638@2|Bacteria,1PER4@1224|Proteobacteria,1RSR0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_4435924_7	314278.NB231_14998	2.1e-35	143.0	COG3090@1|root,COG3090@2|Bacteria,1R4WJ@1224|Proteobacteria,1RZRQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS3_k127_4435924_0	626887.J057_17280	1.166e-167	550.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS3_k127_4435924_6	382464.ABSI01000013_gene1884	1.6e-38	152.0	COG2095@1|root,COG2095@2|Bacteria,46T9S@74201|Verrucomicrobia,2IUN7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS3_k127_4435924_1	349521.HCH_06289	9.501e-146	477.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1XNGP@135619|Oceanospirillales	135619|Oceanospirillales	E	Creatinase/Prolidase N-terminal domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.4.13.9,3.5.4.44	ko:K01271,ko:K15783	ko00260,ko01100,map00260,map01100	-	R09800	RC02661	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_4435924_4	1123023.JIAI01000002_gene5083	6.455e-100	332.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4E011@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_4435924_5	1123023.JIAI01000001_gene6647	5.415e-79	269.0	COG1309@1|root,COG1309@2|Bacteria,2ICRJ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4435924_9	1121948.AUAC01000003_gene2398	2.701e-33	131.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TVNW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_4444089_0	1089552.KI911559_gene2596	6.387e-58	225.0	COG4106@1|root,COG4106@2|Bacteria,1QZ92@1224|Proteobacteria,2TYB6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_31
CMS3_k127_4444089_1	575540.Isop_3045	5.833e-49	184.0	COG0457@1|root,COG0457@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_4456932_6	694429.Pyrfu_0560	1.112e-05	57.0	COG2404@1|root,arCOG00423@2157|Archaea,2XQ04@28889|Crenarchaeota	28889|Crenarchaeota	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_4456932_3	395961.Cyan7425_5205	1.831e-46	181.0	COG0602@1|root,COG0602@2|Bacteria,1G13F@1117|Cyanobacteria,3KFQ2@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_4456932_1	330214.NIDE0342	1.089e-51	209.0	COG1305@1|root,COG1305@2|Bacteria,3J150@40117|Nitrospirae	40117|Nitrospirae	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,Transglut_core
CMS3_k127_4456932_2	1254432.SCE1572_48295	7.126e-47	194.0	COG1721@1|root,COG1721@2|Bacteria,1N8IQ@1224|Proteobacteria,42S2K@68525|delta/epsilon subdivisions,2WNA2@28221|Deltaproteobacteria,2YVGE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4456932_0	1499967.BAYZ01000105_gene3512	4.234e-98	332.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4456932_5	82654.Pse7367_2149	3.233e-07	64.0	COG2755@1|root,COG2755@2|Bacteria,1G3BA@1117|Cyanobacteria	1117|Cyanobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS3_k127_4456932_4	1301098.PKB_0042	5.553e-40	164.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
CMS3_k127_4485764_9	1172180.KB911786_gene226	6.699e-47	180.0	COG1073@1|root,COG1073@2|Bacteria,2I2YU@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_4485764_3	1123023.JIAI01000003_gene2846	2.129e-110	367.0	COG1028@1|root,COG1028@2|Bacteria,2H8QY@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_4485764_2	298654.FraEuI1c_4209	4.023e-114	383.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_4485764_12	66874.JOFS01000017_gene3486	4.392e-39	166.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sig49	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4485764_16	1120950.KB892708_gene4181	1.277e-21	108.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4DS2F@85009|Propionibacteriales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4485764_7	96561.Dole_0398	6.401e-68	243.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2,TetR_C_7,TetR_N
CMS3_k127_4485764_4	502025.Hoch_5094	1.106e-80	287.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,434FJ@68525|delta/epsilon subdivisions,2WYSY@28221|Deltaproteobacteria,2Z0IZ@29|Myxococcales	28221|Deltaproteobacteria	H	Sulfotransferase domain	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CMS3_k127_4485764_0	710687.KI912270_gene5478	2.604e-149	484.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,234WQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
CMS3_k127_4485764_19	1121456.ATVA01000018_gene290	8.441e-17	89.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_4485764_13	1121405.dsmv_2892	4.912e-33	142.0	COG3437@1|root,COG4585@1|root,COG3437@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2X63I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein, histidine kinase dimerization and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_4485764_8	1167006.UWK_00554	2.585e-51	203.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42RQX@68525|delta/epsilon subdivisions,2WNM1@28221|Deltaproteobacteria,2MJTS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4485764_25	1173025.GEI7407_1857	3.306e-05	53.0	COG2197@1|root,COG2197@2|Bacteria,1G5A4@1117|Cyanobacteria,1H7R3@1150|Oscillatoriales	1117|Cyanobacteria	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_4485764_18	551789.ATVJ01000001_gene438	7.373e-17	88.0	COG0457@1|root,COG0457@2|Bacteria,1NG1D@1224|Proteobacteria,2USAE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4485764_17	1219035.NT2_12_00490	6.132e-17	95.0	COG0457@1|root,COG0457@2|Bacteria,1N4QC@1224|Proteobacteria,2UPZU@28211|Alphaproteobacteria,2K4BR@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_4485764_11	1458357.BG58_41110	1.96e-39	174.0	COG1652@1|root,COG3209@1|root,COG1652@2|Bacteria,COG3209@2|Bacteria,1NYE5@1224|Proteobacteria,2W9ZB@28216|Betaproteobacteria,1KBFI@119060|Burkholderiaceae	28216|Betaproteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_4485764_1	1196322.A370_05609	2.412e-140	509.0	COG1388@1|root,COG3209@1|root,COG1388@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,36F1J@31979|Clostridiaceae	186801|Clostridia	M	YD repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	LysM,RHS_repeat
CMS3_k127_4485764_15	1101195.Meth11DRAFT_1148	7.4e-26	117.0	COG0457@1|root,COG0457@2|Bacteria,1NM5V@1224|Proteobacteria,2W62U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4485764_22	216432.CA2559_01455	2.631e-08	65.0	COG0747@1|root,COG1404@1|root,COG2866@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3291@1|root,COG3391@1|root,COG0747@2|Bacteria,COG1404@2|Bacteria,COG2866@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB
CMS3_k127_4485764_24	301.JNHE01000033_gene959	9.661e-06	58.0	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,1SE5I@1236|Gammaproteobacteria,1YFNX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	Bacterial type II/III secretion system short domain	-	-	-	-	-	-	-	-	-	-	-	-	Secretin,Secretin_N
CMS3_k127_4485764_21	237609.PSAKL28_17520	4.746e-11	74.0	COG3728@1|root,32VVZ@2|Bacteria,1N3FD@1224|Proteobacteria,1SCUV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	terminase	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
CMS3_k127_4485764_10	1101195.Meth11DRAFT_1147	4.323e-42	164.0	COG1191@1|root,COG1191@2|Bacteria	2|Bacteria	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	DUF1492,Sigma70_r2,Sigma70_r4
CMS3_k127_4485764_6	349521.HCH_04067	2.466e-76	265.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XHDM@135619|Oceanospirillales	135619|Oceanospirillales	N	Plays a role in the flagellum-specific transport system	-	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
CMS3_k127_4485764_20	349521.HCH_04069	9.872e-17	84.0	COG1886@1|root,COG1886@2|Bacteria,1NN94@1224|Proteobacteria,1SJ4R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
CMS3_k127_4485764_5	1101195.Meth11DRAFT_1142	1.357e-80	283.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2VIV1@28216|Betaproteobacteria,2KKP1@206350|Nitrosomonadales	28216|Betaproteobacteria	N	Flagellar basal body rod	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
CMS3_k127_4485764_14	1217703.F904_01509	5.073e-30	124.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1SDIF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellar hook capping protein - N-terminal region	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD
CMS3_k127_4545859_2	1449069.JMLO01000018_gene586	5.862e-43	165.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4FUTI@85025|Nocardiaceae	201174|Actinobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,TsaE
CMS3_k127_4545859_0	887898.HMPREF0551_0140	3.821e-153	504.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,1K3VV@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS3_k127_4545859_1	1304275.C41B8_14950	2.452e-133	438.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the GARS family	purD	GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01945,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729	GARS_A,GARS_C,GARS_N
CMS3_k127_4570149_4	326427.Cagg_2725	5.453e-68	252.0	COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4570149_8	479434.Sthe_1762	1.106e-26	126.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4570149_0	67373.JOBF01000002_gene1089	2.557e-148	483.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_4570149_7	1120950.KB892707_gene4617	3.96e-30	140.0	2A28U@1|root,30QJI@2|Bacteria,2HCS0@201174|Actinobacteria,4DW9T@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4570149_1	247633.GP2143_13256	8.66e-125	407.0	COG1028@1|root,COG1028@2|Bacteria,1MXNY@1224|Proteobacteria,1RY5U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059,ko:K18335	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10690,R11671	RC00029,RC00089,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_4570149_6	1286093.C266_08812	3.789e-32	139.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,2VZGG@28216|Betaproteobacteria,1KGYH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4570149_3	208444.JNYY01000008_gene8571	9.704e-81	291.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4DYN3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS3_k127_4570149_5	113395.AXAI01000002_gene5239	1.628e-38	153.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria	1224|Proteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_4570149_2	745014.OMB55_00001200	2.466e-86	309.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,1RXYY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	cytochrome p450	bioI	-	-	ko:K21033	-	-	-	-	ko00000,ko00199	-	-	-	p450
CMS3_k127_4570149_9	278963.ATWD01000001_gene3133	1.362e-25	122.0	COG2272@1|root,COG2272@2|Bacteria,3Y6PV@57723|Acidobacteria,2JKXD@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS3_k127_4586420_3	1121033.AUCF01000004_gene4853	2.784e-14	81.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS3_k127_4586420_0	1121921.KB898708_gene1569	9.805e-93	314.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,1RRRU@1236|Gammaproteobacteria,2PMJX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	haloacid dehalogenase-like hydrolase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
CMS3_k127_4586420_1	1095769.CAHF01000006_gene1856	1.765e-51	200.0	COG5637@1|root,COG5637@2|Bacteria,1RCEX@1224|Proteobacteria,2VQP4@28216|Betaproteobacteria,4771P@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS3_k127_4586420_4	591158.SSMG_03886	2.406e-05	56.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_4586420_2	153948.NAL212_0192	1.197e-14	87.0	COG5549@1|root,COG5549@2|Bacteria,1PE84@1224|Proteobacteria,2WC16@28216|Betaproteobacteria,37458@32003|Nitrosomonadales	28216|Betaproteobacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_461595_2	1229780.BN381_290057	3.523e-77	268.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,3UXH6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_461595_4	1535422.ND16A_3018	1.215e-38	165.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,2Q8BG@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Sulfatase	mdoB	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_461595_1	1229780.BN381_150017	4.109e-170	542.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,3UXGG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_461595_3	349163.Acry_2115	3.63e-70	247.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2TSTP@28211|Alphaproteobacteria,2JZBW@204441|Rhodospirillales	204441|Rhodospirillales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_461595_7	1380394.JADL01000003_gene4946	9.264e-20	93.0	COG2315@1|root,COG2315@2|Bacteria,1R292@1224|Proteobacteria,2TZE0@28211|Alphaproteobacteria,2JZ0J@204441|Rhodospirillales	204441|Rhodospirillales	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS3_k127_461595_0	1211815.CBYP010000067_gene115	1.595e-188	597.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4ETRJ@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE1_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_461595_5	402881.Plav_2827	2.581e-29	121.0	COG1051@1|root,COG1051@2|Bacteria,1QU5T@1224|Proteobacteria,2TW0R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_4648596_21	290397.Adeh_1561	1.506e-14	81.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria	1224|Proteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_4648596_12	438753.AZC_2306	3.586e-89	303.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,3EYDG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS3_k127_4648596_9	867903.ThesuDRAFT_00054	6.622e-106	355.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,3WCET@538999|Clostridiales incertae sedis	186801|Clostridia	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS3_k127_4648596_18	1382315.JPOI01000001_gene1276	5.685e-40	154.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,1WGDI@129337|Geobacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_4648596_19	1254432.SCE1572_23140	1.408e-35	150.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1PQD2@1224|Proteobacteria,4323R@68525|delta/epsilon subdivisions,2WXJB@28221|Deltaproteobacteria,2Z10C@29|Myxococcales	28221|Deltaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_1,TPR_17,TPR_8
CMS3_k127_4648596_23	502025.Hoch_4957	4.006e-07	56.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_4648596_14	96561.Dole_1514	3.569e-67	245.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2WK3K@28221|Deltaproteobacteria,2MM49@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
CMS3_k127_4648596_0	682795.AciX8_2408	1.47e-245	794.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_4648596_7	266117.Rxyl_0743	1.24e-147	477.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CMS3_k127_4648596_16	479432.Sros_1482	5.62e-47	178.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,4EFV9@85012|Streptosporangiales	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_4648596_15	1123023.JIAI01000001_gene5999	1.206e-47	184.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,4E22I@85010|Pseudonocardiales	201174|Actinobacteria	I	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_4648596_8	1278073.MYSTI_04818	2.828e-129	436.0	COG0183@1|root,COG0183@2|Bacteria,1PSXC@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
CMS3_k127_4648596_3	58123.JOFJ01000004_gene1786	1.696e-176	577.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria,4EHB7@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
CMS3_k127_4648596_1	66874.JOFS01000005_gene4107	2.175e-219	695.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_4648596_20	1229780.BN381_250095	4.952e-18	88.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CMS3_k127_4648596_6	1078020.KEK_14188	5.866e-148	481.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,23301@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE26	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4648596_11	525368.HMPREF0591_5137	3.785e-97	331.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria,236CQ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_4648596_2	1313172.YM304_02310	1.821e-218	691.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_4648596_10	1137799.GZ78_07695	4.315e-102	359.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria,1XPGT@135619|Oceanospirillales	135619|Oceanospirillales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4648596_4	1137799.GZ78_07680	6.453e-166	556.0	COG0183@1|root,COG0183@2|Bacteria,1NSYR@1224|Proteobacteria,1SJW4@1236|Gammaproteobacteria,1XR8M@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4648596_5	1157635.KB892046_gene5616	5.49e-161	515.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
CMS3_k127_4648596_17	685727.REQ_43530	7.866e-44	164.0	COG2030@1|root,COG2030@2|Bacteria,2IHT0@201174|Actinobacteria,4G0Q2@85025|Nocardiaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_4648596_13	83406.HDN1F_01650	7.284e-88	300.0	COG1545@1|root,COG1545@2|Bacteria,1R44D@1224|Proteobacteria,1RYXA@1236|Gammaproteobacteria,1J9N1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,MaoC_dehydrat_N,OB_aCoA_assoc
CMS3_k127_4674511_2	344747.PM8797T_20403	2.696e-46	188.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
CMS3_k127_4674511_0	986075.CathTA2_0628	9.248e-171	547.0	COG0160@1|root,COG0160@2|Bacteria,1TRUG@1239|Firmicutes,4HBUU@91061|Bacilli	91061|Bacilli	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_4674511_3	344747.PM8797T_20423	1.21e-38	154.0	COG1846@1|root,COG1846@2|Bacteria,2J0SE@203682|Planctomycetes	203682|Planctomycetes	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS3_k127_4674511_1	1123023.JIAI01000005_gene678	7.86e-74	260.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4E5P5@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA4	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_4720778_0	1333998.M2A_2721	2.072e-114	384.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TRWW@28211|Alphaproteobacteria,4BR2E@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_4720778_2	1174684.EBMC1_15799	1.181e-51	196.0	COG0627@1|root,COG0627@2|Bacteria,1R4M6@1224|Proteobacteria,2U4X7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CMS3_k127_4720778_3	570268.ANBB01000020_gene4348	2.014e-41	171.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4EFKW@85012|Streptosporangiales	201174|Actinobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
CMS3_k127_4720778_1	385682.AFSL01000039_gene152	1.29e-81	282.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,2FMMZ@200643|Bacteroidia,3XIMR@558415|Marinilabiliaceae	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS3_k127_474618_12	1454004.AW11_00692	1.488e-13	84.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_474618_11	913865.DOT_5284	4.453e-17	95.0	COG5650@1|root,COG5650@2|Bacteria,1TQVD@1239|Firmicutes,25CFN@186801|Clostridia,2618M@186807|Peptococcaceae	186801|Clostridia	S	integral membrane protein	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2
CMS3_k127_474618_1	929558.SMGD1_0478	2.602e-99	335.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2YMSE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS3_k127_474618_6	1123242.JH636434_gene4961	1.255e-46	187.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_474618_9	926550.CLDAP_02300	2.952e-29	137.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi	200795|Chloroflexi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_474618_5	886293.Sinac_1864	1.025e-63	240.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CMS3_k127_474618_7	404380.Gbem_3306	9.928e-44	169.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,42VEH@68525|delta/epsilon subdivisions,2WVST@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS3_k127_474618_3	926550.CLDAP_31240	6.026e-97	337.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_474618_0	706587.Desti_2066	8.971e-102	355.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_474618_4	1205680.CAKO01000006_gene3202	3.064e-70	249.0	COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2TUTF@28211|Alphaproteobacteria,2JSIT@204441|Rhodospirillales	204441|Rhodospirillales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
CMS3_k127_474618_8	883.DvMF_1922	8.882e-31	139.0	2AQSQ@1|root,31G0I@2|Bacteria,1QDT0@1224|Proteobacteria,435RS@68525|delta/epsilon subdivisions,2X06E@28221|Deltaproteobacteria,2MAU4@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_474618_2	1333998.M2A_2494	1.358e-97	340.0	2EXDM@1|root,33QQ7@2|Bacteria,1NTQ6@1224|Proteobacteria,2UQVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_474618_10	1282876.BAOK01000001_gene1681	5.757e-27	119.0	COG1309@1|root,COG1309@2|Bacteria,1NJZH@1224|Proteobacteria,2URBM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4763827_1	399739.Pmen_3228	2.984e-124	411.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1YDPH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4763827_8	37919.EP51_02570	7.513e-21	96.0	2EVB2@1|root,33NRN@2|Bacteria,2H0F2@201174|Actinobacteria,4G60I@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4763827_2	37919.EP51_02575	8.372e-95	340.0	COG2267@1|root,COG2267@2|Bacteria,2I473@201174|Actinobacteria,4G0IJ@85025|Nocardiaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4763827_5	156889.Mmc1_0444	5.674e-50	201.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria	1224|Proteobacteria	O	DSBA oxidoreductase	MA20_20720	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
CMS3_k127_4763827_7	1283283.ATXA01000002_gene2474	1.882e-33	134.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4EWG2@85013|Frankiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS3_k127_4763827_9	1173264.KI913949_gene1346	5.111e-07	63.0	COG5305@1|root,COG5305@2|Bacteria,1G0MG@1117|Cyanobacteria,1H7N3@1150|Oscillatoriales	1117|Cyanobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4763827_4	1121937.AUHJ01000002_gene3556	1.268e-68	267.0	2DBGS@1|root,2Z95N@2|Bacteria,1QSNI@1224|Proteobacteria,1RR96@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4763827_6	1121937.AUHJ01000004_gene1164	2.371e-42	168.0	2DMXI@1|root,32U9G@2|Bacteria,1NFAA@1224|Proteobacteria,1SRGT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4763827_3	706587.Desti_3270	5.426e-73	280.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_4763827_0	266117.Rxyl_0070	3.904e-129	444.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS3_k127_4796738_54	279238.Saro_1152	0.0008566	51.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria,2K1U9@204457|Sphingomonadales	204457|Sphingomonadales	E	COG2755 Lysophospholipase L1 and related esterases	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS3_k127_4796738_39	335543.Sfum_3567	1.288e-34	152.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,2MSID@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_4796738_1	1380390.JIAT01000009_gene906	2.533e-207	682.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
CMS3_k127_4796738_48	1254432.SCE1572_00345	1.039e-15	87.0	2EI76@1|root,33BYI@2|Bacteria,1RBW7@1224|Proteobacteria,42QZD@68525|delta/epsilon subdivisions,2WN6J@28221|Deltaproteobacteria,2YXMN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4796738_51	1205680.CAKO01000040_gene984	3.242e-06	53.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_4796738_21	1254432.SCE1572_14445	1.456e-90	332.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YWIW@29|Myxococcales	28221|Deltaproteobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CMS3_k127_4796738_12	1254432.SCE1572_20295	5.061e-107	355.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42Z9B@68525|delta/epsilon subdivisions,2WMPJ@28221|Deltaproteobacteria,2YTYW@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS3_k127_4796738_18	251229.Chro_2996	8.748e-97	322.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,3VJ25@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS3_k127_4796738_49	1173027.Mic7113_1148	1.566e-10	74.0	COG0477@1|root,COG1359@1|root,COG0477@2|Bacteria,COG1359@2|Bacteria,1GQD9@1117|Cyanobacteria,1HI6N@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS3_k127_4796738_11	644282.Deba_1045	1.021e-108	371.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4796738_44	1131269.AQVV01000038_gene1566	9.504e-24	109.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	mltC	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08306,ko:K08308,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iAF1260.b1193,iB21_1397.B21_01178,iBWG_1329.BWG_1018,iECBD_1354.ECBD_2429,iECB_1328.ECB_01168,iECDH10B_1368.ECDH10B_1246,iECDH1ME8569_1439.ECDH1ME8569_1132,iECD_1391.ECD_01168,iEcDH1_1363.EcDH1_2455,iEcolC_1368.EcolC_2432,iG2583_1286.G2583_3622,iJO1366.b1193,iUMNK88_1353.UMNK88_1507,iUMNK88_1353.UMNK88_3661,iY75_1357.Y75_RS06225	DUF3393,SLT
CMS3_k127_4796738_26	1254432.SCE1572_46300	2.398e-79	291.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,42MX2@68525|delta/epsilon subdivisions,2WIUV@28221|Deltaproteobacteria,2Z2KR@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_4796738_31	404380.Gbem_2210	8.99e-60	218.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,42RPV@68525|delta/epsilon subdivisions,2WNQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4796738_15	448385.sce6663	3.982e-102	342.0	COG2267@1|root,COG2267@2|Bacteria,1MYEX@1224|Proteobacteria,43CP1@68525|delta/epsilon subdivisions,2X7WC@28221|Deltaproteobacteria,2Z2N6@29|Myxococcales	28221|Deltaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4796738_42	381666.H16_A0147	2.008e-28	132.0	COG2021@1|root,COG2021@2|Bacteria,1QU84@1224|Proteobacteria,2VRYJ@28216|Betaproteobacteria,1K0JE@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM alpha beta hydrolase fold	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_4796738_37	1265310.CCBD010000031_gene1747	7.215e-46	185.0	COG2128@1|root,COG2128@2|Bacteria,2IAC5@201174|Actinobacteria,236CM@1762|Mycobacteriaceae	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_4796738_29	1403819.BATR01000156_gene5187	4.203e-69	252.0	COG2706@1|root,COG2706@2|Bacteria,46Z3W@74201|Verrucomicrobia,2IW4S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4796738_22	172088.AUGA01000037_gene3720	7.882e-87	312.0	COG0654@1|root,COG0654@2|Bacteria,1MX9R@1224|Proteobacteria,2TR4U@28211|Alphaproteobacteria,3JSWT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.14.13.127	ko:K05712,ko:K20218	ko00360,ko00623,ko01120,ko01220,map00360,map00623,map01120,map01220	M00545	R06786,R06787,R11197,R11198	RC00236,RC00389	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS3_k127_4796738_50	335543.Sfum_2170	1.044e-08	65.0	2AVEY@1|root,31M6X@2|Bacteria,1QJ1U@1224|Proteobacteria,4322P@68525|delta/epsilon subdivisions,2WWRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
CMS3_k127_4796738_41	1304885.AUEY01000108_gene2930	3.634e-29	130.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,42NJB@68525|delta/epsilon subdivisions,2WM62@28221|Deltaproteobacteria,2MI1G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
CMS3_k127_4796738_23	566466.NOR53_2920	3.313e-84	289.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,1RYA7@1236|Gammaproteobacteria,1J9TF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS3_k127_4796738_34	1122603.ATVI01000008_gene2316	3.818e-51	194.0	COG3327@1|root,COG3327@2|Bacteria,1RABS@1224|Proteobacteria,1S2WE@1236|Gammaproteobacteria,1X6K8@135614|Xanthomonadales	135614|Xanthomonadales	K	PaaX-like protein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PaaX,PaaX_C
CMS3_k127_4796738_9	1283283.ATXA01000003_gene1699	3.233e-122	421.0	COG1804@1|root,COG1804@2|Bacteria,2GMGE@201174|Actinobacteria	201174|Actinobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_4796738_0	557599.MKAN_07990	1.572e-209	669.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,23361@1762|Mycobacteriaceae	201174|Actinobacteria	P	flavoprotein involved in K transport	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
CMS3_k127_4796738_45	1157637.KB892121_gene273	2.891e-23	111.0	2E0AM@1|root,32VXZ@2|Bacteria,2IMA6@201174|Actinobacteria	201174|Actinobacteria	S	Nitrile hydratase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	NHase_beta
CMS3_k127_4796738_28	68570.DC74_1033	3.709e-70	265.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Nitrile hydratase alpha	-	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
CMS3_k127_4796738_36	1476876.JOJO01000011_gene3282	1.558e-49	183.0	28I45@1|root,2Z87Q@2|Bacteria,2I95R@201174|Actinobacteria	201174|Actinobacteria	S	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
CMS3_k127_4796738_27	1333998.M2A_2232	2.865e-73	269.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TVNW@28211|Alphaproteobacteria,4BS8D@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.13.239	ko:K22443	-	-	-	-	ko00000,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_4796738_47	1500304.JQKY01000003_gene573	3.649e-18	98.0	COG0491@1|root,COG0491@2|Bacteria,1N6PM@1224|Proteobacteria,2TRZ4@28211|Alphaproteobacteria,4BB94@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4796738_25	861299.J421_5736	8.575e-83	303.0	KOG1573@1|root,2Z822@2|Bacteria	2|Bacteria	S	Inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
CMS3_k127_4796738_8	316058.RPB_2657	5.168e-123	402.0	COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,2TVH8@28211|Alphaproteobacteria,3JS6S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	KR domain	MA20_36825	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4796738_38	1519464.HY22_09850	3.726e-41	168.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
CMS3_k127_4796738_24	765912.Thimo_2015	6.865e-84	291.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1WXTE@135613|Chromatiales	135613|Chromatiales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_4796738_20	1108045.GORHZ_075_00200	1.093e-91	330.0	COG5361@1|root,COG5361@2|Bacteria,2HES3@201174|Actinobacteria,4GH56@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
CMS3_k127_4796738_13	247634.GPB2148_3614	6.693e-107	362.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	GO:0003674,GO:0003824,GO:0005575,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016782,GO:0031224,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044425,GO:0046505,GO:0046506,GO:0071704,GO:1901576	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4796738_2	1283283.ATXA01000001_gene1168	1.433e-192	616.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4796738_35	335283.Neut_2463	4.691e-51	197.0	COG2010@1|root,COG2041@1|root,COG2010@2|Bacteria,COG2041@2|Bacteria,1N9MS@1224|Proteobacteria,2W0PY@28216|Betaproteobacteria,374QE@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_4796738_33	211114.JOEF01000013_gene4937	3.679e-51	205.0	COG0302@1|root,COG0302@2|Bacteria,2ID0X@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase I	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydroI
CMS3_k127_4796738_3	1341151.ASZU01000003_gene2312	8.826e-146	478.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,27AXN@186824|Thermoactinomycetaceae	91061|Bacilli	G	Pyruvate kinase, alpha/beta domain	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
CMS3_k127_4796738_17	316055.RPE_2302	2.428e-99	328.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,3JU3S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	MA20_32390	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_3,GST_N
CMS3_k127_4796738_5	742740.HMPREF9474_01437	4.831e-140	452.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,21YS9@1506553|Lachnoclostridium	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_4796738_30	402881.Plav_0923	9.842e-64	246.0	COG1028@1|root,COG1028@2|Bacteria,1MUWC@1224|Proteobacteria,2TV32@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CMS3_k127_4796738_6	1298864.AUEQ01000020_gene3499	1.144e-128	438.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria,235UZ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
CMS3_k127_4796738_16	1237149.C900_00371	1.262e-100	338.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_4796738_19	314278.NB231_04125	3.36e-93	312.0	COG3751@1|root,COG3751@2|Bacteria,1RAJ8@1224|Proteobacteria,1S3II@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4796738_4	1192034.CAP_5247	1.831e-142	477.0	COG3973@1|root,COG3973@2|Bacteria,1P638@1224|Proteobacteria,42MXR@68525|delta/epsilon subdivisions,2WK1Z@28221|Deltaproteobacteria,2Z32G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD_C_2
CMS3_k127_4796738_40	471857.Svir_38270	2.28e-34	143.0	COG3871@1|root,COG3871@2|Bacteria,2I2QZ@201174|Actinobacteria,4E4E6@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_4796738_43	309807.SRU_1802	9.765e-27	117.0	COG3030@1|root,COG3030@2|Bacteria,4PERU@976|Bacteroidetes,1FJHJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
CMS3_k127_4796738_10	1280949.HAD_05580	1.564e-121	406.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TQUY@28211|Alphaproteobacteria,440PV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4796738_32	329726.AM1_0952	5.735e-53	214.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,1G2QW@1117|Cyanobacteria	1117|Cyanobacteria	CT	cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
CMS3_k127_4796738_14	384765.SIAM614_27158	1.415e-104	347.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA thioesterase	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
CMS3_k127_4796738_7	1123367.C666_00120	3.641e-125	422.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,2KUFR@206389|Rhodocyclales	206389|Rhodocyclales	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_4810187_17	745718.JADT01000005_gene95	3.565e-66	238.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4810187_39	543728.Vapar_0172	1.777e-08	68.0	COG1807@1|root,COG1807@2|Bacteria,1N02M@1224|Proteobacteria,2W18W@28216|Betaproteobacteria,4AHD0@80864|Comamonadaceae	28216|Betaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4810187_11	439235.Dalk_1881	3.58e-91	325.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4810187_29	596152.DesU5LDRAFT_2631	1.073e-42	177.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_4810187_38	1167006.UWK_03393	9.962e-10	72.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,2MJPQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS3_k127_4810187_42	880072.Desac_0777	5.984e-06	53.0	COG1686@1|root,COG1686@2|Bacteria,1ND9M@1224|Proteobacteria,42VIN@68525|delta/epsilon subdivisions,2WSBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S11 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4810187_18	1227499.C493_03345	6.671e-64	239.0	COG3119@1|root,arCOG02787@2157|Archaea,2XUWX@28890|Euryarchaeota,23S64@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_4810187_44	56107.Cylst_5060	0.0002285	50.0	2DB7J@1|root,2Z7MI@2|Bacteria,1G2I3@1117|Cyanobacteria,1HJGU@1161|Nostocales	1117|Cyanobacteria	S	PFAM S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
CMS3_k127_4810187_15	1123242.JH636434_gene4961	3.871e-74	276.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_4810187_25	1123242.JH636434_gene5235	4.445e-47	194.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_4810187_26	439235.Dalk_0190	1.113e-46	188.0	COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_4810187_10	448385.sce1736	8.909e-94	323.0	COG0372@1|root,COG0789@1|root,COG0372@2|Bacteria,COG0789@2|Bacteria,1MXFW@1224|Proteobacteria,43B14@68525|delta/epsilon subdivisions,2X6FA@28221|Deltaproteobacteria,2YX0F@29|Myxococcales	28221|Deltaproteobacteria	C	Helix-turn-helix domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
CMS3_k127_4810187_32	1225785.CM001983_gene3302	3.303e-36	148.0	COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
CMS3_k127_4810187_22	1248916.ANFY01000011_gene1088	2.615e-50	188.0	COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,2U5SU@28211|Alphaproteobacteria,2K42G@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N_3
CMS3_k127_4810187_12	1329516.JPST01000019_gene2688	7.498e-89	308.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27BB2@186824|Thermoactinomycetaceae	91061|Bacilli	I	Thiolase, C-terminal domain	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4810187_8	561175.KB894094_gene2054	8.537e-110	368.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_4810187_34	797114.C475_12537	2.301e-30	139.0	COG3119@1|root,arCOG02785@2157|Archaea,2XV54@28890|Euryarchaeota,23UWR@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_4810187_2	298655.KI912266_gene4987	2.822e-157	546.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4ETPN@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_4810187_31	502025.Hoch_0331	7.647e-38	161.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS3_k127_4810187_9	113395.AXAI01000002_gene5235	3.887e-102	342.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_4810187_35	1279019.ARQK01000048_gene139	6.352e-24	106.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ1Y@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_4810187_27	1125863.JAFN01000001_gene366	3.492e-46	186.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	penicillin-binding protein	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
CMS3_k127_4810187_28	570952.ATVH01000013_gene2750	1.51e-45	172.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2JRTS@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0694 Thioredoxin-like proteins and domains	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
CMS3_k127_4810187_41	765912.Thimo_0875	3.346e-07	61.0	COG0546@1|root,COG0546@2|Bacteria,1RHA9@1224|Proteobacteria,1SHRV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4810187_40	391735.Veis_4173	3.613e-08	64.0	COG1106@1|root,COG1106@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
CMS3_k127_4810187_21	1385517.N800_10135	6.557e-54	198.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,1X61F@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4810187_16	573413.Spirs_1644	2.427e-69	256.0	COG2265@1|root,COG2265@2|Bacteria,2J5Y7@203691|Spirochaetes	203691|Spirochaetes	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	ygcA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS3_k127_4810187_19	1449357.JQLK01000001_gene1992	7.967e-57	214.0	COG1253@1|root,COG1253@2|Bacteria,1WI7Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_4810187_1	595537.Varpa_3624	6.219e-209	690.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,4AAFY@80864|Comamonadaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_4810187_4	1192034.CAP_2432	3.238e-131	451.0	COG0303@1|root,COG0303@2|Bacteria	2|Bacteria	H	'Molybdopterin	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_4810187_6	1125863.JAFN01000001_gene443	8.29e-128	434.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS3_k127_4810187_43	309801.trd_1311	1.965e-05	55.0	COG1977@1|root,COG1977@2|Bacteria,2GBBB@200795|Chloroflexi,27Z8W@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_4810187_14	1125863.JAFN01000001_gene1090	6.216e-80	286.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
CMS3_k127_4810187_33	1229909.NSED_08030	2.231e-31	125.0	COG2154@1|root,arCOG02939@2157|Archaea,41SSQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS3_k127_4810187_30	101510.RHA1_ro05122	2.394e-38	162.0	COG2030@1|root,COG2030@2|Bacteria,2GIXP@201174|Actinobacteria,4G8TI@85025|Nocardiaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_4810187_7	1282876.BAOK01000001_gene3302	4.018e-111	373.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2TU8W@28211|Alphaproteobacteria,4BT6G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4810187_3	1396418.BATQ01000116_gene4615	2.601e-137	456.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
CMS3_k127_4810187_37	1379698.RBG1_1C00001G0140	5.178e-10	66.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD,Excalibur
CMS3_k127_4810187_13	649638.Trad_0374	4.73e-80	278.0	KOG2524@1|root,2ZJ84@2|Bacteria	2|Bacteria	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
CMS3_k127_4810187_20	502025.Hoch_2148	1.216e-56	210.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_4810187_0	264462.Bd2784	0.0	1008.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2MTH2@213481|Bdellovibrionales,2WIIV@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	aconitate hydratase	aco	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_4810187_36	1137799.GZ78_12955	1.199e-19	104.0	COG2911@1|root,COG2931@1|root,COG3533@1|root,COG5276@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3533@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,He_PIG,OmpA_membrane,fn3
CMS3_k127_4810187_5	404589.Anae109_0920	3.464e-128	439.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_4810187_24	1458357.BG58_25900	2.452e-47	181.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,2VPHU@28216|Betaproteobacteria,1KGYJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4810187_23	1282876.BAOK01000001_gene990	5.047e-48	182.0	COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,2UG76@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N_3
CMS3_k127_4887982_3	290397.Adeh_3929	6.426e-116	382.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_4887982_6	1313172.YM304_03860	2.746e-54	215.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
CMS3_k127_4887982_7	1121918.ARWE01000001_gene180	1.224e-32	135.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS3_k127_4887982_2	1282876.BAOK01000001_gene3466	1.499e-123	411.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,2U5M0@28211|Alphaproteobacteria,4BT1G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_4887982_4	383372.Rcas_1705	9.582e-94	328.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_4887982_10	557598.LHK_01966	5.483e-06	61.0	COG1132@1|root,COG1132@2|Bacteria,1RDIA@1224|Proteobacteria,2VR6J@28216|Betaproteobacteria,2KSYE@206351|Neisseriales	206351|Neisseriales	V	Domain of unknown function (DUF1854)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1854
CMS3_k127_4887982_1	661478.OP10G_2981	5.128e-142	481.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	mdlB	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4887982_0	1121937.AUHJ01000001_gene365	3.487e-143	501.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria	1224|Proteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_4887982_9	690850.Desaf_0799	2.95e-25	111.0	2C8BN@1|root,32RKS@2|Bacteria,1N7Z0@1224|Proteobacteria,42WEU@68525|delta/epsilon subdivisions,2WS8J@28221|Deltaproteobacteria,2MCC5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4887982_5	1242864.D187_000680	1.73e-73	264.0	COG2518@1|root,COG2518@2|Bacteria,1QX9V@1224|Proteobacteria,42Z9X@68525|delta/epsilon subdivisions,2WUEX@28221|Deltaproteobacteria,2YX7N@29|Myxococcales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4895595_2	1123504.JQKD01000012_gene1257	5.098e-45	175.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria,4AH2J@80864|Comamonadaceae	28216|Betaproteobacteria	C	CoA-transferase family III	bbsE	-	2.8.3.15	ko:K07543	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS3_k127_4895595_3	1299327.I546_6651	1.586e-22	108.0	COG5285@1|root,COG5285@2|Bacteria,2HSYC@201174|Actinobacteria,23EJ4@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_4895595_0	1177154.Y5S_01004	8.918e-91	312.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,1S1Y5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_4895595_5	47716.JOFH01000005_gene1370	1.148e-10	73.0	COG2030@1|root,COG2030@2|Bacteria,2GXE5@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_4895595_1	1313172.YM304_02500	1.11e-75	265.0	COG1028@1|root,COG1028@2|Bacteria,2I32I@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4895595_4	296587.XP_002505458.1	2.945e-12	68.0	COG2017@1|root,KOG1604@2759|Eukaryota,37SGG@33090|Viridiplantae,34IYV@3041|Chlorophyta	3041|Chlorophyta	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS3_k127_5037222_15	225937.HP15_4020	3.313e-17	98.0	COG3103@1|root,COG3103@2|Bacteria,1QXFZ@1224|Proteobacteria,1RPAR@1236|Gammaproteobacteria,465YC@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
CMS3_k127_5037222_1	1313172.YM304_26210	4.334e-238	762.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4CMW5@84992|Acidimicrobiia	201174|Actinobacteria	CJ	CoA binding domain	acdA1	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS3_k127_5037222_5	1173026.Glo7428_0230	9.761e-164	544.0	COG1115@1|root,COG1115@2|Bacteria,1G1I5@1117|Cyanobacteria	1117|Cyanobacteria	U	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS3_k127_5037222_2	1268068.PG5_65010	1.47e-227	739.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.5.5,1.1.9.1	ko:K00114,ko:K17760,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
CMS3_k127_5037222_17	1123288.SOV_2c11600	0.0001189	52.0	COG3005@1|root,COG3005@2|Bacteria,1VBE7@1239|Firmicutes,4H57H@909932|Negativicutes	909932|Negativicutes	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
CMS3_k127_5037222_10	1123024.AUII01000012_gene4102	1.039e-84	294.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4E39N@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5037222_12	391625.PPSIR1_21949	5.62e-43	171.0	COG4341@1|root,COG4341@2|Bacteria,1N0MY@1224|Proteobacteria	1224|Proteobacteria	S	HD phosphohydrolase	-	-	1.13.11.78	ko:K21196	ko00440,map00440	-	R10722	RC03261	ko00000,ko00001,ko01000	-	-	-	HD
CMS3_k127_5037222_9	391625.PPSIR1_21954	2.016e-95	329.0	COG5285@1|root,COG5285@2|Bacteria,1N31I@1224|Proteobacteria	1224|Proteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.46	ko:K21195	ko00440,map00440	-	R10724	RC01107	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_5037222_13	331678.Cphamn1_0612	1.448e-42	163.0	COG3152@1|root,COG3152@2|Bacteria,1FFF6@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
CMS3_k127_5037222_16	566466.NOR53_479	9.348e-12	72.0	29GUQ@1|root,2ZIQ9@2|Bacteria,1P89M@1224|Proteobacteria,1STDV@1236|Gammaproteobacteria,1JBAC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_5037222_6	426117.M446_4314	2.461e-163	532.0	COG1409@1|root,COG1409@2|Bacteria,1N44U@1224|Proteobacteria,2U456@28211|Alphaproteobacteria,1JRTH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	N terminal of Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosC,MetallophosN
CMS3_k127_5037222_4	589865.DaAHT2_2137	1.112e-169	550.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2MHTU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5037222_7	1205680.CAKO01000030_gene4951	4.086e-111	389.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,2JPS1@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N
CMS3_k127_5037222_3	177437.HRM2_10270	1.128e-208	673.0	COG0531@1|root,COG0531@2|Bacteria,1R4IZ@1224|Proteobacteria,42MTQ@68525|delta/epsilon subdivisions,2WK39@28221|Deltaproteobacteria,2MIIG@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
CMS3_k127_5037222_14	35128.Thaps22645	1.835e-41	168.0	2EF9S@1|root,2T4ED@2759|Eukaryota,2XEWT@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5037222_0	1150469.RSPPHO_00624	4.374e-261	815.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2JPZX@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS3_k127_5037222_8	1265502.KB905976_gene510	2.23e-105	360.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VHAW@28216|Betaproteobacteria,4ABEZ@80864|Comamonadaceae	28216|Betaproteobacteria	I	6-phosphogluconate dehydrogenase, NAD-binding	glxR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS3_k127_5037222_11	448385.sce2802	9.919e-48	178.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YUG7@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD/H associated	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS3_k127_5062947_5	344747.PM8797T_23856	1.254e-48	194.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5062947_9	402881.Plav_2853	2.276e-08	66.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2TVI8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS3_k127_5062947_4	745014.OMB55_00020240	4.468e-52	206.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS3_k127_5062947_7	247634.GPB2148_1443	1.73e-24	104.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS3_k127_5062947_6	1112204.GPOL_c00690	1.771e-43	176.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,4GDHU@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_5062947_2	713586.KB900536_gene469	5.322e-70	253.0	COG0477@1|root,COG2814@2|Bacteria,1RCII@1224|Proteobacteria	1224|Proteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5062947_0	493475.GARC_2412	8.008e-108	362.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,1S1KW@1236|Gammaproteobacteria,46A2K@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
CMS3_k127_5062947_1	595460.RRSWK_01941	1.025e-72	260.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5062947_3	1144275.COCOR_07842	6.407e-63	239.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2Z2WE@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
CMS3_k127_5062947_8	1333523.L593_04960	2.512e-20	104.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5085243_5	1242864.D187_003502	6.061e-48	194.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	SMART helicase c2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RNase_T,ResIII
CMS3_k127_5085243_1	1382306.JNIM01000001_gene3478	3.147e-155	511.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short
CMS3_k127_5085243_8	1121918.ARWE01000001_gene3542	2.471e-29	124.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS3_k127_5085243_2	483219.LILAB_23000	2.747e-127	418.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2YXED@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_5085243_3	518766.Rmar_0596	7.993e-123	415.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
CMS3_k127_5085243_7	1233950.IW22_13560	4.086e-41	168.0	2FAQS@1|root,342Y5@2|Bacteria,4P44W@976|Bacteroidetes,1I9M9@117743|Flavobacteriia,3ZRI8@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_5085243_6	224911.27349089	1.888e-44	171.0	COG0596@1|root,COG0596@2|Bacteria,1Q4C8@1224|Proteobacteria,2TTW5@28211|Alphaproteobacteria,3JTEC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	MA20_23630	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_5085243_0	298654.FraEuI1c_3304	2.213e-188	612.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_5085243_4	1227500.C494_20173	9.481e-50	187.0	COG0438@1|root,arCOG01409@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_5086704_2	870967.VIS19158_15614	2.519e-33	136.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,1S8UW@1236|Gammaproteobacteria,1XX8X@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
CMS3_k127_5086704_1	643648.Slip_0153	1.75e-43	174.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,42KJI@68298|Syntrophomonadaceae	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	dltB	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
CMS3_k127_5086704_0	472759.Nhal_3600	2.713e-150	510.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1WXKG@135613|Chromatiales	135613|Chromatiales	DM	mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM,MscS_porin
CMS3_k127_5146978_39	1198114.AciX9_1614	7.264e-07	58.0	2ED8Q@1|root,33759@2|Bacteria,3Y5NT@57723|Acidobacteria,2JJWR@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
CMS3_k127_5146978_0	756272.Plabr_0481	7.001e-288	894.0	COG0422@1|root,COG0422@2|Bacteria,2IWV7@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
CMS3_k127_5146978_36	1131269.AQVV01000022_gene2246	2.631e-15	85.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmI	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02198,ko:K02200	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmH,TPR_19,TPR_2
CMS3_k127_5146978_37	215803.DB30_5455	5.429e-13	84.0	COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
CMS3_k127_5146978_8	529818.AMSG_11506T0	2.511e-118	425.0	29QRV@1|root,2RX97@2759|Eukaryota	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_5146978_38	237368.SCABRO_03007	7.441e-08	67.0	2A1MP@1|root,30PVX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5146978_3	880073.Calab_2811	1.832e-166	547.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2NPC4@2323|unclassified Bacteria	2|Bacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,TrkA_C,Voltage_CLC
CMS3_k127_5146978_22	1125863.JAFN01000001_gene1790	2.86e-41	159.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_5146978_7	1121935.AQXX01000089_gene4656	6.833e-131	433.0	COG0655@1|root,COG0655@2|Bacteria,1N5Q7@1224|Proteobacteria,1RY1K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CMS3_k127_5146978_9	1231392.OCGS_2088	2.224e-104	365.0	COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,2TS20@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0025 NhaP-type Na H and K H antiporters	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS3_k127_5146978_33	45157.CMH050CT	1.025e-26	127.0	COG2138@1|root,2RXIW@2759|Eukaryota	2759|Eukaryota	S	sirohydrochlorin cobaltochelatase activity	-	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
CMS3_k127_5146978_41	314256.OG2516_04336	7.977e-05	49.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,2PDMF@252301|Oceanicola	28211|Alphaproteobacteria	C	Domain of unknown function (DUF4445)	nqrF	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS3_k127_5146978_19	502025.Hoch_3949	1.306e-51	191.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2X3AE@28221|Deltaproteobacteria,2YV4E@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS3_k127_5146978_4	102232.GLO73106DRAFT_00034980	2.25e-158	509.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
CMS3_k127_5146978_26	1172185.KB911533_gene34	3.219e-35	141.0	2E1KM@1|root,32WY3@2|Bacteria,2GUNE@201174|Actinobacteria	201174|Actinobacteria	S	Methylmuconolactone methyl-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	EthD
CMS3_k127_5146978_11	314285.KT71_05632	1.777e-79	273.0	COG1917@1|root,COG1917@2|Bacteria,1QU6U@1224|Proteobacteria,1T1P4@1236|Gammaproteobacteria,1J7FW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
CMS3_k127_5146978_24	1047013.AQSP01000130_gene1852	1.642e-38	154.0	COG0730@1|root,COG0730@2|Bacteria,2NQW7@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	VVA0548	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_5146978_6	1142394.PSMK_21440	3.302e-136	460.0	COG0141@1|root,COG0141@2|Bacteria,2IXQ3@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS3_k127_5146978_27	926560.KE387027_gene530	7.527e-34	150.0	COG0454@1|root,COG0454@2|Bacteria,1WN0W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_5146978_12	861299.J421_0654	4.475e-76	275.0	29XIJ@1|root,30J9H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5146978_31	1120983.KB894572_gene2997	7.695e-29	121.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5146978_5	266117.Rxyl_0056	2.04e-138	451.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
CMS3_k127_5146978_28	1437824.BN940_12701	1.029e-32	134.0	COG2153@1|root,COG3150@1|root,COG2153@2|Bacteria,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria,3T3HP@506|Alcaligenaceae	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0227)	yqiA	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
CMS3_k127_5146978_14	313612.L8106_06314	2.948e-63	227.0	29YYU@1|root,30KVP@2|Bacteria,1G64N@1117|Cyanobacteria,1HB5C@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_5146978_29	1410616.JHXE01000001_gene2613	2.069e-30	136.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5146978_23	935863.AWZR01000003_gene2845	2.582e-39	163.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1X7Y9@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferases group 1	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_5146978_35	1449049.JONW01000006_gene2704	8.5e-16	89.0	2C4HP@1|root,33HN5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5146978_17	1463856.JOHY01000024_gene4552	5.587e-57	223.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS3_k127_5146978_15	1442599.JAAN01000035_gene689	9.002e-61	219.0	COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria,1X6N0@135614|Xanthomonadales	135614|Xanthomonadales	L	alkylated DNA	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
CMS3_k127_5146978_42	400682.PAC_15727235	0.0002898	49.0	2DZDY@1|root,2S6YB@2759|Eukaryota,3AAGA@33154|Opisthokonta,3C2VQ@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_5146978_40	529818.AMSG_00272T0	1.129e-06	53.0	2DZDY@1|root,2S6YB@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_5146978_10	247634.GPB2148_2967	4.772e-86	299.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,1RY4N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	xdh	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_5146978_13	1232410.KI421428_gene1030	1.172e-74	261.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_5146978_1	402881.Plav_0817	9.933e-229	764.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,1JNCY@119043|Rhodobiaceae	28211|Alphaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_5146978_2	402881.Plav_0818	1.91e-188	606.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2U3UT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_5146978_30	575540.Isop_1966	3.995e-29	130.0	COG0561@1|root,COG0561@2|Bacteria,2J0VT@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS3_k127_5146978_34	1210884.HG799472_gene14768	3.186e-26	119.0	COG0727@1|root,COG0727@2|Bacteria,2IZM1@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS3_k127_5146978_25	479434.Sthe_0226	1.468e-37	155.0	COG3153@1|root,COG3153@2|Bacteria,2G7B4@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
CMS3_k127_5146978_21	1123399.AQVE01000019_gene1632	6.674e-43	166.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,4634E@72273|Thiotrichales	72273|Thiotrichales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
CMS3_k127_5146978_16	1121272.KB903272_gene315	2.232e-60	233.0	COG2334@1|root,COG2334@2|Bacteria,2I2JR@201174|Actinobacteria,4D9XM@85008|Micromonosporales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5146978_18	290397.Adeh_2250	4.62e-52	200.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigM	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
CMS3_k127_5146978_20	1298863.AUEP01000019_gene3529	2.619e-50	184.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4DT5X@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_5165407_21	745014.OMB55_00020020	1.585e-22	109.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_5165407_17	204669.Acid345_2555	3.539e-32	146.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_2555|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5165407_27	933262.AXAM01000018_gene1009	4.571e-06	60.0	COG0501@1|root,COG3063@1|root,COG0501@2|Bacteria,COG3063@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria,2MIHI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_11,TPR_17
CMS3_k127_5165407_23	1266909.AUAG01000007_gene2343	7.649e-18	89.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1WYSK@135613|Chromatiales	135613|Chromatiales	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
CMS3_k127_5165407_24	1385935.N836_09330	3.218e-11	75.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5165407_6	637389.Acaty_c2451	9.426e-100	350.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,2NC2H@225057|Acidithiobacillales	225057|Acidithiobacillales	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_5165407_4	717231.Flexsi_1371	1.08e-104	376.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_5165407_5	502025.Hoch_6012	5.069e-100	340.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,2Z2YT@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS3_k127_5165407_1	83406.HDN1F_10410	2.538e-183	587.0	COG1960@1|root,COG1960@2|Bacteria,1R81V@1224|Proteobacteria,1SM92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5165407_11	1279017.AQYJ01000029_gene3738	6.866e-50	184.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,467NM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_5165407_12	1144275.COCOR_00284	7.579e-47	183.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_5165407_7	1040989.AWZU01000001_gene5528	6.764e-81	284.0	COG0400@1|root,COG0400@2|Bacteria,1P51S@1224|Proteobacteria,2TT0Y@28211|Alphaproteobacteria,3JU1C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS3_k127_5165407_14	313606.M23134_00707	2.909e-43	169.0	KOG3539@1|root,32TPV@2|Bacteria,4NMI6@976|Bacteroidetes,47VU6@768503|Cytophagia	976|Bacteroidetes	S	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
CMS3_k127_5165407_0	483219.LILAB_20720	0.0	1203.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YUJ6@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_5165407_3	1212548.B381_01919	5.526e-123	411.0	COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,1RNBM@1236|Gammaproteobacteria,1Z16K@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	ybdG	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
CMS3_k127_5165407_9	502025.Hoch_5381	6.515e-67	254.0	COG4221@1|root,COG4221@2|Bacteria,1QVTE@1224|Proteobacteria	1224|Proteobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	yueD	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5165407_8	644966.Tmar_1443	3.479e-71	252.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia	186801|Clostridia	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS3_k127_5165407_22	10160.XP_004633325.1	7.9e-22	108.0	KOG1584@1|root,KOG1584@2759|Eukaryota,39EUR@33154|Opisthokonta,3BG39@33208|Metazoa,3CT89@33213|Bilateria,48QPR@7711|Chordata,49M9S@7742|Vertebrata,3J7V8@40674|Mammalia,359F0@314146|Euarchontoglires,4PX9R@9989|Rodentia	33208|Metazoa	S	Sulfotransferase	SULT1C3	GO:0003674,GO:0003824,GO:0004027,GO:0004062,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0044237,GO:0044424,GO:0044444,GO:0044464	2.8.2.4	ko:K01016,ko:K01025	ko00140,map00140	-	R02350	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CMS3_k127_5165407_19	1242864.D187_008608	7.079e-29	134.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_5165407_2	1429916.X566_01950	4.91e-162	530.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TV8M@28211|Alphaproteobacteria,3JTR2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	MA20_03405	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5165407_13	1197130.BAFM01000001_gene22	5.382e-46	192.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5165407_10	886293.Sinac_7114	6.903e-57	215.0	COG3119@1|root,COG3119@2|Bacteria,2IXUK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_5165407_16	1047013.AQSP01000131_gene1840	4.329e-33	144.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_5165407_15	378806.STAUR_0270	3.262e-33	138.0	COG0782@1|root,COG0782@2|Bacteria,1MZNI@1224|Proteobacteria,42VKP@68525|delta/epsilon subdivisions,2WSC9@28221|Deltaproteobacteria,2YXDH@29|Myxococcales	28221|Deltaproteobacteria	K	Transcription elongation factor, GreA/GreB, C-term	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
CMS3_k127_5165407_18	391937.NA2_00005	1.103e-29	136.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2TT0E@28211|Alphaproteobacteria,43HE0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_5165407_25	685778.AORL01000021_gene922	6.53e-09	68.0	2ES5B@1|root,33JQ4@2|Bacteria,1NHPR@1224|Proteobacteria,2UN83@28211|Alphaproteobacteria,2K67H@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_5165407_20	1040987.AZUY01000007_gene748	1.399e-22	106.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria,43JFG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_22745	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_5170085_8	1278073.MYSTI_06926	6.465e-76	258.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,42YFC@68525|delta/epsilon subdivisions,2WU03@28221|Deltaproteobacteria,2YUBP@29|Myxococcales	28221|Deltaproteobacteria	I	desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_5170085_15	1122223.KB890700_gene2118	3.005e-05	57.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1WJBW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_5170085_4	1211115.ALIQ01000033_gene1987	6.694e-94	321.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2TU6K@28211|Alphaproteobacteria,3NBF6@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_5170085_5	671143.DAMO_2569	1.497e-93	336.0	COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_5170085_3	396588.Tgr7_0173	1.3e-95	339.0	COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,1WZWK@135613|Chromatiales	135613|Chromatiales	G	pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_5170085_9	45157.CMT058CT	2.228e-62	221.0	COG0299@1|root,KOG3076@2759|Eukaryota	2759|Eukaryota	F	phosphoribosylglycinamide formyltransferase activity	-	-	2.1.2.2,6.3.3.1,6.3.4.13	ko:K00601,ko:K11787,ko:K11788	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R04144,R04208,R04325,R04326	RC00026,RC00090,RC00166,RC00197,RC01100,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	AICARFT_IMPCHas,AIRS,AIRS_C,Formyl_trans_N,GARS_A,GARS_C,GARS_N
CMS3_k127_5170085_11	1283300.ATXB01000001_gene426	2.208e-45	181.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_5170085_13	234267.Acid_7037	5.689e-20	104.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
CMS3_k127_5170085_10	278963.ATWD01000001_gene2368	8.672e-58	224.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	-	-	-	-	-	-	-	-	-	IMS
CMS3_k127_5170085_12	880073.Calab_0502	8.451e-22	108.0	COG1402@1|root,COG1402@2|Bacteria,2NRF3@2323|unclassified Bacteria	2|Bacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS3_k127_5170085_2	1242864.D187_003813	5.446e-100	341.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS3_k127_5170085_7	1110502.TMO_0943	5.676e-82	291.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2JQ0D@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
CMS3_k127_5170085_0	113395.AXAI01000002_gene5237	1.868e-151	503.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,2VF18@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5170085_1	472759.Nhal_2285	3.684e-117	392.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,1S2UH@1236|Gammaproteobacteria,1WYPZ@135613|Chromatiales	135613|Chromatiales	P	PFAM Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS3_k127_5170085_6	1268237.G114_11190	5.382e-83	282.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1Y3SW@135624|Aeromonadales	135624|Aeromonadales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS3_k127_5198951_6	1116369.KB890024_gene2468	2.007e-09	69.0	COG0494@1|root,COG0494@2|Bacteria,1N8EV@1224|Proteobacteria,2TTNV@28211|Alphaproteobacteria,43GQH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Nudix hydrolase	MA20_36340	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_5198951_3	402881.Plav_1641	1.751e-44	183.0	COG5031@1|root,COG5031@2|Bacteria,1RGXT@1224|Proteobacteria,2U8F1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	ko:K18586	-	-	-	-	ko00000	-	-	-	Coq4
CMS3_k127_5198951_1	448385.sce0600	6.695e-73	272.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,43F2R@68525|delta/epsilon subdivisions,2X35T@28221|Deltaproteobacteria,2YUDS@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
CMS3_k127_5198951_7	987059.RBXJA2T_01200	4.407e-07	63.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1KMJ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_5198951_0	76114.ebA6902	1.16e-139	460.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KU97@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5198951_4	394221.Mmar10_0780	6.266e-33	148.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,43XUF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9
CMS3_k127_5198951_2	1121937.AUHJ01000006_gene2410	6.927e-60	216.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_5198951_5	1279019.ARQK01000048_gene139	1.265e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ1Y@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_5217108_21	457570.Nther_1660	1.519e-13	77.0	COG3360@1|root,COG3360@2|Bacteria,1VF2X@1239|Firmicutes,24QS4@186801|Clostridia	186801|Clostridia	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS3_k127_5217108_22	1122603.ATVI01000005_gene3692	1.406e-05	57.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the ompA family	mopB	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
CMS3_k127_5217108_16	565045.NOR51B_630	2.802e-27	115.0	2FG7R@1|root,34844@2|Bacteria,1P1QM@1224|Proteobacteria,1SRGS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5217108_0	400668.Mmwyl1_0216	5.568e-228	789.0	COG0754@1|root,COG3942@1|root,COG0754@2|Bacteria,COG3942@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria,1XHKB@135619|Oceanospirillales	135619|Oceanospirillales	E	Glutathionylspermidine synthase	-	-	3.5.1.78,6.3.1.8	ko:K01460	ko00480,ko01100,map00480,map01100	-	R01917,R01918	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CHAP,GSP_synth
CMS3_k127_5217108_3	2002.JOEQ01000040_gene6075	5.132e-99	335.0	COG1073@1|root,COG1073@2|Bacteria,2I3JW@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5217108_9	548477.HMPREF0294_0332	4.62e-59	236.0	COG2885@1|root,COG3266@1|root,COG2885@2|Bacteria,COG3266@2|Bacteria,2I6XH@201174|Actinobacteria,22MTB@1653|Corynebacteriaceae	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,TSP_3,YSIRK_signal
CMS3_k127_5217108_18	96561.Dole_2043	2.254e-20	108.0	COG1800@1|root,COG2885@1|root,COG3420@1|root,COG1800@2|Bacteria,COG2885@2|Bacteria,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5217108_11	1121374.KB891576_gene371	3.977e-44	173.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	-	-	-	ko:K02479,ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_5217108_7	1000565.METUNv1_02697	1.773e-70	269.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K20975	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_5217108_6	247639.MGP2080_13298	1.904e-80	278.0	COG1028@1|root,COG1028@2|Bacteria,1R80D@1224|Proteobacteria,1S4BT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_5217108_15	1313172.YM304_29330	4.85e-28	118.0	COG1359@1|root,COG1359@2|Bacteria,2GTWJ@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_5217108_13	1313172.YM304_24650	4.749e-39	155.0	COG3871@1|root,COG3871@2|Bacteria,2INWZ@201174|Actinobacteria	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
CMS3_k127_5217108_8	215803.DB30_5550	6.891e-62	232.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,43BFU@68525|delta/epsilon subdivisions,2X5HG@28221|Deltaproteobacteria,2YUGC@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS3_k127_5217108_17	1121381.JNIV01000018_gene4161	1.592e-20	96.0	COG0735@1|root,COG0735@2|Bacteria,1WJXU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_5217108_4	1144275.COCOR_07392	2.105e-96	349.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_5217108_1	1297742.A176_06088	2.086e-162	518.0	COG1409@1|root,COG1409@2|Bacteria,1MUQJ@1224|Proteobacteria,42ZV7@68525|delta/epsilon subdivisions,2WVFR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_5217108_12	663610.JQKO01000015_gene1841	2.755e-41	177.0	COG3258@1|root,COG3258@2|Bacteria,1N1U2@1224|Proteobacteria,2U82E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5217108_10	1167006.UWK_01412	2.276e-55	208.0	2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,42W26@68525|delta/epsilon subdivisions,2WSHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5217108_20	469383.Cwoe_1093	2.689e-14	85.0	COG2508@1|root,COG2508@2|Bacteria,2GR38@201174|Actinobacteria	201174|Actinobacteria	QT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
CMS3_k127_5217108_2	1464048.JNZS01000033_gene2794	7.125e-101	346.0	COG1075@1|root,COG1075@2|Bacteria,2HXFM@201174|Actinobacteria,4DI5G@85008|Micromonosporales	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
CMS3_k127_5217108_23	1288079.AUKN01000008_gene5869	0.0002043	53.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria	201174|Actinobacteria	S	deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Hemerythrin
CMS3_k127_5217108_5	196490.AUEZ01000027_gene1696	1.31e-94	324.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,3JU8V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
CMS3_k127_5217108_19	91464.S7335_873	9.755e-15	83.0	COG3832@1|root,COG3832@2|Bacteria,1G73V@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_5217108_14	306281.AJLK01000131_gene1394	2.471e-29	119.0	COG0640@1|root,COG0640@2|Bacteria,1G6T4@1117|Cyanobacteria,1JM2R@1189|Stigonemataceae	1117|Cyanobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_5249173_11	391165.GbCGDNIH1_0959	6.794e-48	174.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2JS4R@204441|Rhodospirillales	204441|Rhodospirillales	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_5249173_10	1121378.KB899697_gene2932	8.248e-53	215.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
CMS3_k127_5249173_9	309801.trd_0606	3.899e-55	211.0	COG0309@1|root,COG0309@2|Bacteria,2G8E4@200795|Chloroflexi,27XEQ@189775|Thermomicrobia	189775|Thermomicrobia	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
CMS3_k127_5249173_2	298654.FraEuI1c_3325	6.057e-116	414.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_5249173_3	1219035.NT2_08_01320	4.85e-107	355.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,2K3NY@204457|Sphingomonadales	204457|Sphingomonadales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5249173_4	1370120.AUWR01000016_gene3770	4.932e-96	336.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,2360H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phosphotriesterase	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
CMS3_k127_5249173_17	1192868.CAIU01000030_gene3904	6.523e-19	99.0	COG1396@1|root,COG3837@1|root,COG1396@2|Bacteria,COG3837@2|Bacteria,1RBF3@1224|Proteobacteria,2VEYB@28211|Alphaproteobacteria,43JVF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS3_k127_5249173_19	1379281.AVAG01000033_gene496	2.951e-12	78.0	COG2350@1|root,COG2350@2|Bacteria,1Q3X6@1224|Proteobacteria,42XXW@68525|delta/epsilon subdivisions,2WSXF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_5249173_6	1380391.JIAS01000011_gene5103	5.199e-69	261.0	COG0558@1|root,COG0558@2|Bacteria,1MYE7@1224|Proteobacteria,2TSMC@28211|Alphaproteobacteria,2JS2R@204441|Rhodospirillales	1224|Proteobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_5249173_7	671143.DAMO_3062	2.411e-62	244.0	COG1213@1|root,COG1213@2|Bacteria,2NQ1B@2323|unclassified Bacteria	2|Bacteria	M	MobA-like NTP transferase domain	aepX	-	2.7.7.74,2.7.8.34,5.4.2.9	ko:K01841,ko:K07281,ko:K07291	ko00440,ko00562,ko01100,ko01120,ko01130,map00440,map00562,map01100,map01120,map01130	-	R00661,R09669,R09670	RC00002,RC00078,RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,NTP_transferase,PEP_mutase
CMS3_k127_5249173_13	240015.ACP_0207	2.836e-42	169.0	COG1765@1|root,COG1765@2|Bacteria,3Y7VV@57723|Acidobacteria,2JN4F@204432|Acidobacteriia	204432|Acidobacteriia	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_5249173_14	304371.MCP_2723	2.439e-41	175.0	COG1287@1|root,arCOG02043@2157|Archaea,2XX8Q@28890|Euryarchaeota,2NADZ@224756|Methanomicrobia	224756|Methanomicrobia	M	Oligosaccharyl transferase STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
CMS3_k127_5249173_15	96561.Dole_2588	1.792e-36	157.0	COG1807@1|root,COG1807@2|Bacteria,1RK4G@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5249173_5	1131269.AQVV01000017_gene1952	2.982e-94	351.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000017_gene1952|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5249173_8	1267535.KB906767_gene4838	1.685e-58	221.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_5249173_1	1282876.BAOK01000002_gene502	2.705e-119	395.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_5249173_20	56780.SYN_00762	7.97e-11	71.0	2E6CS@1|root,3310E@2|Bacteria,1N2FR@1224|Proteobacteria,42UY2@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5249173_18	990285.RGCCGE502_25608	8.401e-16	85.0	COG0346@1|root,COG0346@2|Bacteria,1Q88M@1224|Proteobacteria,2VEEH@28211|Alphaproteobacteria,4BE93@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_5249173_0	1254432.SCE1572_33210	2.804e-191	627.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2Z1M7@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase type-B family	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
CMS3_k127_5249173_12	215803.DB30_8464	8.852e-47	193.0	COG0421@1|root,COG0457@1|root,COG0421@2|Bacteria,COG0457@2|Bacteria,1QXA2@1224|Proteobacteria,43C3D@68525|delta/epsilon subdivisions,2WUH2@28221|Deltaproteobacteria,2YYH4@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_5249173_16	404589.Anae109_1825	1.412e-25	113.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_5253514_0	321327.CYA_0286	4.967e-220	693.0	COG0065@1|root,COG0065@2|Bacteria,1G1J0@1117|Cyanobacteria,1GZ9E@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS3_k127_5253514_10	416348.Hlac_0871	3.064e-52	208.0	COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,23S0Z@183963|Halobacteria	183963|Halobacteria	E	3-isopropylmalate dehydratase, small subunit	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS3_k127_5253514_9	290397.Adeh_1666	9.278e-65	253.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2YWMX@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1716	ECH_1
CMS3_k127_5253514_14	1282876.BAOK01000001_gene2732	1.196e-29	129.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2U0NZ@28211|Alphaproteobacteria,4BSP2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1499)	MA20_07395	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS3_k127_5253514_1	1313172.YM304_24080	1.513e-198	633.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CNF1@84992|Acidimicrobiia	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_5253514_12	861299.J421_0471	7.492e-47	195.0	COG2010@1|root,COG2010@2|Bacteria,1ZUJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5253514_2	1380347.JNII01000010_gene2597	3.871e-194	668.0	COG0156@1|root,COG0156@2|Bacteria,2GQWK@201174|Actinobacteria	201174|Actinobacteria	H	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,Aminotran_1_2
CMS3_k127_5253514_15	1122201.AUAZ01000001_gene2452	9.195e-18	100.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T5IB@1236|Gammaproteobacteria,46DB7@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
CMS3_k127_5253514_13	1242864.D187_000260	3.449e-34	153.0	COG3735@1|root,COG3735@2|Bacteria,1Q122@1224|Proteobacteria,43EW3@68525|delta/epsilon subdivisions,2X269@28221|Deltaproteobacteria,2Z29B@29|Myxococcales	28221|Deltaproteobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS3_k127_5253514_4	261292.Nit79A3_0543	1.749e-131	426.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,2WBU3@28216|Betaproteobacteria,373TA@32003|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Sulfotransferase	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CMS3_k127_5253514_11	1229780.BN381_110039	3.862e-52	193.0	2DEEQ@1|root,2ZMPQ@2|Bacteria,2I4E7@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5253514_3	266117.Rxyl_2540	3.224e-156	541.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_5253514_8	402881.Plav_1769	2.331e-77	291.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,1JQ1K@119043|Rhodobiaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_5253514_5	1206741.BAFX01000099_gene1021	2.373e-103	346.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria,4FXBD@85025|Nocardiaceae	201174|Actinobacteria	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
CMS3_k127_5253514_6	439235.Dalk_1881	2.319e-99	346.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5253514_7	41431.PCC8801_0005	3.879e-85	290.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
CMS3_k127_5276877_22	1169161.KB897719_gene3565	5.583e-27	115.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria	2|Bacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS3_k127_5276877_25	1357279.N018_01750	1.513e-13	80.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1T0G6@1236|Gammaproteobacteria,1ZAMR@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_5276877_6	1254432.SCE1572_25705	4.106e-91	310.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2YUEF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS3_k127_5276877_26	207559.Dde_1379	2.428e-13	81.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WNIP@28221|Deltaproteobacteria,2MG3G@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS3_k127_5276877_7	1333998.M2A_1969	3.601e-89	300.0	COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,2TVJ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	MA20_23730	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_5276877_10	1229780.BN381_80298	9.416e-81	277.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_5276877_17	492774.JQMB01000005_gene5351	1.685e-50	189.0	COG0346@1|root,COG0346@2|Bacteria,1NJ3K@1224|Proteobacteria,2UM27@28211|Alphaproteobacteria,4BDQN@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_5276877_12	861299.J421_4466	4.069e-72	278.0	COG0153@1|root,COG0153@2|Bacteria,1ZU6F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS3_k127_5276877_9	1131269.AQVV01000001_gene1363	3.957e-83	310.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5276877_8	269799.Gmet_1014	1.3e-87	306.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5276877_0	926550.CLDAP_07340	0.0	1093.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_5276877_2	926569.ANT_05360	2.165e-156	515.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
CMS3_k127_5276877_21	926550.CLDAP_10540	1.599e-33	142.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_5276877_27	1118060.CAGZ01000014_gene1516	2.032e-12	82.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CV66@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS3_k127_5276877_14	521674.Plim_3400	1.828e-54	220.0	COG0515@1|root,COG0515@2|Bacteria,2IYEQ@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_5276877_4	1319815.HMPREF0202_02878	3.223e-107	359.0	COG0180@1|root,COG0180@2|Bacteria,37854@32066|Fusobacteria	32066|Fusobacteria	J	Psort location Cytoplasmic, score	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS3_k127_5276877_15	1159870.KB907784_gene354	3.139e-53	199.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,3T8SY@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_5276877_1	118166.JH976538_gene5242	6.181e-201	636.0	COG4992@1|root,COG4992@2|Bacteria,1G4MC@1117|Cyanobacteria	1117|Cyanobacteria	E	Aminotransferase class-III	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_5276877_11	443143.GM18_3440	6.538e-77	269.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_5276877_28	797303.Natpe_2811	1.971e-06	57.0	arCOG02282@1|root,arCOG02282@2157|Archaea,2XWJ2@28890|Euryarchaeota,23V5G@183963|Halobacteria	183963|Halobacteria	K	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS3_k127_5276877_18	161528.ED21_22643	3.296e-46	177.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,2K4ZJ@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_5276877_19	246200.SPO0620	1.047e-38	153.0	COG0500@1|root,COG2226@2|Bacteria,1N6XG@1224|Proteobacteria	1224|Proteobacteria	Q	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_5276877_13	1220535.IMCC14465_03730	1.409e-68	257.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2UTT0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS3_k127_5276877_23	481448.Minf_0142	1.334e-25	124.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_5276877_20	419947.MRA_0339	8.891e-37	148.0	COG1309@1|root,COG1309@2|Bacteria,2IIIS@201174|Actinobacteria,23DK1@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5276877_16	1172186.KB911465_gene4397	3.818e-52	212.0	COG2114@1|root,COG2909@1|root,COG3629@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3629@2|Bacteria,2GJAR@201174|Actinobacteria,2349V@1762|Mycobacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
CMS3_k127_5276877_3	219305.MCAG_03092	1.667e-134	432.0	COG2334@1|root,COG2334@2|Bacteria,2HZ9Z@201174|Actinobacteria,4D9TY@85008|Micromonosporales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5276877_24	1123023.JIAI01000001_gene6793	3.204e-21	97.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	ynjA	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5276877_5	1278309.KB907109_gene3298	3.47e-94	320.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S49E@1236|Gammaproteobacteria,1XHSX@135619|Oceanospirillales	135619|Oceanospirillales	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
CMS3_k127_5284935_17	1254432.SCE1572_38940	9.73e-06	57.0	2AN96@1|root,31D78@2|Bacteria,1QAAX@1224|Proteobacteria,434Y2@68525|delta/epsilon subdivisions,2WZ8X@28221|Deltaproteobacteria,2Z1KT@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS3_k127_5284935_16	1463821.JOGR01000004_gene2428	5.914e-07	62.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_5284935_10	1472716.KBK24_0127670	1.953e-51	203.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,2VVVZ@28216|Betaproteobacteria,1K3EF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	ko:K13006,ko:K19429	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
CMS3_k127_5284935_15	445972.ANACOL_00824	5.833e-12	78.0	COG5650@1|root,COG5650@2|Bacteria,1TQVD@1239|Firmicutes,25CFN@186801|Clostridia,3WM5M@541000|Ruminococcaceae	186801|Clostridia	S	integral membrane protein	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2
CMS3_k127_5284935_8	1511.CLOST_0444	2.805e-75	280.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,25RKZ@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS3_k127_5284935_5	645991.Sgly_1553	4.069e-102	352.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,25ZZI@186807|Peptococcaceae	186801|Clostridia	E	PFAM DegT DnrJ EryC1 StrS aminotransferase family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_5284935_9	1116472.MGMO_45c00700	4.049e-55	201.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales	135618|Methylococcales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
CMS3_k127_5284935_2	1380346.JNIH01000031_gene1013	3.247e-217	715.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS3_k127_5284935_6	448385.sce0176	1.835e-94	332.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42PRS@68525|delta/epsilon subdivisions,2X5EU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_5284935_13	1254432.SCE1572_01640	7.999e-43	171.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K02624,ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
CMS3_k127_5284935_3	1089552.KI911559_gene1098	2.562e-124	406.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2JPM8@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon-nitrogen hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_5284935_7	269799.Gmet_3389	5.552e-84	294.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,43TCP@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS3_k127_5284935_4	1122951.ATUE01000005_gene1809	2.166e-121	408.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,3NJMZ@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_5284935_1	251221.35210719	1.111e-286	893.0	COG0365@1|root,COG0365@2|Bacteria,1G0E7@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_5284935_12	1121861.KB899939_gene3789	1.863e-49	204.0	COG3023@1|root,COG3023@2|Bacteria,1R5WA@1224|Proteobacteria,2UBNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2,SH3_3
CMS3_k127_5284935_0	391625.PPSIR1_34168	0.0	1111.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2WM7X@28221|Deltaproteobacteria,2YUEI@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
CMS3_k127_5284935_11	373903.Hore_01680	7.415e-50	199.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WADU@53433|Halanaerobiales	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS3_k127_5284935_14	1282876.BAOK01000001_gene3163	3.67e-29	126.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,MAM,Peptidase_M14,fn3
CMS3_k127_5428282_1	1144275.COCOR_07754	8.452e-105	354.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WKBG@28221|Deltaproteobacteria,2YYAD@29|Myxococcales	28221|Deltaproteobacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
CMS3_k127_5428282_4	96561.Dole_1053	3.368e-66	231.0	COG2128@1|root,COG2128@2|Bacteria,1PSNE@1224|Proteobacteria,42XCT@68525|delta/epsilon subdivisions,2WSJD@28221|Deltaproteobacteria,2MP2A@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5428282_2	331869.BAL199_16908	3.575e-89	311.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,4BRM7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_17615	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_5428282_0	1122951.ATUE01000006_gene956	2.823e-146	476.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,3NIGQ@468|Moraxellaceae	1236|Gammaproteobacteria	I	synthase III	fabH	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_5428282_5	1071679.BG57_20615	9.27e-11	74.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria,1K29V@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
CMS3_k127_5428282_3	358220.C380_02525	1.668e-77	266.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,4ACVJ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS3_k127_5493853_8	378806.STAUR_8261	1.083e-38	160.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WKBG@28221|Deltaproteobacteria,2YYAD@29|Myxococcales	28221|Deltaproteobacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
CMS3_k127_5493853_3	1279038.KB907348_gene3100	1.045e-93	327.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS3_k127_5493853_6	648757.Rvan_0772	2.132e-59	231.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,3N6VW@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS3_k127_5493853_1	1177179.A11A3_04775	0.0	1295.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XIHW@135619|Oceanospirillales	135619|Oceanospirillales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
CMS3_k127_5493853_4	402881.Plav_3077	1.849e-92	317.0	28M2T@1|root,2ZAH6@2|Bacteria,1R6GW@1224|Proteobacteria,2U25T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5493853_9	28564.XP_002486819.1	1.53e-29	134.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NXT8@4751|Fungi,3RDUS@4890|Ascomycota,20NAJ@147545|Eurotiomycetes,3SBCW@5042|Eurotiales	4751|Fungi	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5,F-box-like,SPRY
CMS3_k127_5493853_7	96561.Dole_2005	6.052e-53	206.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14,SLH
CMS3_k127_5493853_0	1123368.AUIS01000007_gene2749	0.0	1651.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,2NBUJ@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CMS3_k127_5493853_2	713586.KB900536_gene646	9.628e-186	641.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1WW57@135613|Chromatiales	135613|Chromatiales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
CMS3_k127_5493853_5	1394178.AWOO02000005_gene3707	3.449e-84	289.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria,4EJ2J@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5549279_11	575540.Isop_3197	5.622e-09	67.0	COG0438@1|root,COG0438@2|Bacteria,2IZ69@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS3_k127_5549279_12	420662.Mpe_A2727	5.52e-07	62.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcaC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K00754,ko:K13684	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	DUF3880,Glyco_trans_1_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5549279_2	234267.Acid_4459	8.859e-109	368.0	COG0079@1|root,COG0079@2|Bacteria,3Y3Q8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5549279_0	1396418.BATQ01000127_gene2553	5.356e-169	555.0	COG0659@1|root,COG2066@1|root,COG0659@2|Bacteria,COG2066@2|Bacteria,46USD@74201|Verrucomicrobia,2ITM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	ET	Glutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Glutaminase,cNMP_binding
CMS3_k127_5549279_8	1238182.C882_1053	3.686e-57	205.0	COG1309@1|root,COG1309@2|Bacteria,1RC7C@1224|Proteobacteria,2U5YR@28211|Alphaproteobacteria,2JSGT@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5549279_3	1250232.JQNJ01000001_gene3216	9.74e-103	342.0	COG3000@1|root,COG3000@2|Bacteria,4NI62@976|Bacteroidetes,1I9FZ@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_5549279_4	247634.GPB2148_2290	1.808e-88	327.0	COG2199@1|root,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	ydaM	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016740,GO:0016772,GO:0016779,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043900,GO:0043902,GO:0044093,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051252,GO:0052621,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1903506,GO:2000112,GO:2001141	2.7.7.65	ko:K19707,ko:K21088	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko03021	-	-	-	GGDEF,PAS_4,PAS_8,PAS_9
CMS3_k127_5549279_5	330084.JNYZ01000047_gene2915	9.315e-83	285.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4EBZH@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5549279_9	996637.SGM_0832	1.141e-45	172.0	COG0346@1|root,COG0346@2|Bacteria,2IG7M@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_5549279_10	1469245.JFBG01000045_gene2204	4.032e-33	148.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,1S22D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	decarboxylase	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
CMS3_k127_5549279_6	1313172.YM304_37540	2.124e-65	248.0	COG0778@1|root,COG0778@2|Bacteria,2HG55@201174|Actinobacteria,4CNHY@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Nitroreductase family	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CMS3_k127_5549279_7	1282876.BAOK01000001_gene1825	5.208e-60	222.0	COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,2U1WS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS3_k127_5549279_1	566466.NOR53_2184	2.55e-136	443.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1J9FE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_5592718_0	502025.Hoch_1494	1.469e-177	584.0	2CC7E@1|root,2Z7WG@2|Bacteria,1R77M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5592718_5	1049564.TevJSym_ar00550	4.47e-89	300.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,1J5S6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	walR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5592718_3	1121396.KB893080_gene898	8.244e-116	400.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2WU4G@28221|Deltaproteobacteria,2MMQM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_5592718_13	1121918.ARWE01000001_gene1618	8.983e-44	169.0	28TMI@1|root,2ZFV4@2|Bacteria,1R9YK@1224|Proteobacteria,4308H@68525|delta/epsilon subdivisions,2WVGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
CMS3_k127_5592718_12	251221.35214818	4.252e-45	184.0	COG1807@1|root,COG1807@2|Bacteria,1GCPV@1117|Cyanobacteria	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5592718_15	765420.OSCT_0663	2.019e-38	163.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi,376JU@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5592718_9	1499967.BAYZ01000125_gene2598	7.381e-55	222.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
CMS3_k127_5592718_10	1047013.AQSP01000106_gene1773	2.09e-50	201.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS3_k127_5592718_6	1167006.UWK_01387	7.043e-78	272.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42UHH@68525|delta/epsilon subdivisions,2WQ9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Pseudouridine synthase	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
CMS3_k127_5592718_11	391596.PBAL39_19459	4.884e-47	192.0	COG0564@1|root,COG0564@2|Bacteria,4NE9B@976|Bacteroidetes	976|Bacteroidetes	J	Pseudouridine synthase, RluA family	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
CMS3_k127_5592718_4	42256.RradSPS_2004	4.749e-94	334.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4CQGG@84995|Rubrobacteria	84995|Rubrobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CMS3_k127_5592718_8	298655.KI912266_gene2536	2.244e-55	211.0	COG1028@1|root,COG1028@2|Bacteria,2I4ES@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5592718_1	666685.R2APBS1_3632	2.066e-159	523.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1X4AG@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS3_k127_5592718_17	675635.Psed_4350	1.972e-27	129.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5592718_16	1380394.JADL01000001_gene2170	1.043e-34	138.0	COG0346@1|root,COG0346@2|Bacteria,1NFR3@1224|Proteobacteria,2UMIM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_5592718_14	797114.C475_12537	2.816e-43	181.0	COG3119@1|root,arCOG02785@2157|Archaea,2XV54@28890|Euryarchaeota,23UWR@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5592718_7	667632.KB890165_gene2578	4.439e-56	217.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,1K5WB@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg,cNMP_binding
CMS3_k127_5592718_2	1313172.YM304_00880	4.748e-145	477.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria	201174|Actinobacteria	Q	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
CMS3_k127_5605439_8	1229780.BN381_10281	2.23e-103	351.0	COG2030@1|root,COG2030@2|Bacteria,2GJJI@201174|Actinobacteria,3UXJQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	htdY	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
CMS3_k127_5605439_25	67373.JOBF01000012_gene3992	9.066e-18	93.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5605439_2	366602.Caul_5303	1.555e-169	539.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,2KF1F@204458|Caulobacterales	204458|Caulobacterales	E	Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5605439_23	1254432.SCE1572_45265	2.236e-23	112.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_5605439_10	573413.Spirs_0830	3.759e-86	299.0	COG0059@1|root,COG0059@2|Bacteria,2J60P@203691|Spirochaetes	203691|Spirochaetes	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS3_k127_5605439_9	326424.FRAAL3250	2.383e-96	333.0	COG0477@1|root,COG2814@2|Bacteria,2H1TJ@201174|Actinobacteria,4EUWV@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5605439_21	1173027.Mic7113_6656	5.017e-33	145.0	COG4974@1|root,COG4974@2|Bacteria,1G2HC@1117|Cyanobacteria,1H78I@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS3_k127_5605439_1	745310.G432_10700	2.41e-199	640.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,2K32Q@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
CMS3_k127_5605439_13	633149.Bresu_3037	5.858e-74	271.0	COG1524@1|root,COG3119@1|root,COG1524@2|Bacteria,COG3119@2|Bacteria,1R5V5@1224|Proteobacteria,2U1UW@28211|Alphaproteobacteria,2KI1C@204458|Caulobacterales	204458|Caulobacterales	P	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_5605439_6	928724.SacglDRAFT_03472	8.738e-110	367.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4DYCH@85010|Pseudonocardiales	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS3_k127_5605439_15	1382359.JIAL01000001_gene2999	3.214e-54	213.0	COG0591@1|root,COG0591@2|Bacteria,3Y419@57723|Acidobacteria,2JM46@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS3_k127_5605439_22	1123508.JH636440_gene2089	7.43e-25	113.0	COG2905@1|root,COG2905@2|Bacteria,2J53V@203682|Planctomycetes	203682|Planctomycetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_5605439_5	1333998.M2A_0959	8.382e-130	435.0	COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,2TU6R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhaA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_5605439_19	59374.Fisuc_2714	2.216e-42	179.0	COG0440@1|root,COG0440@2|Bacteria	2|Bacteria	E	acetolactate synthase activity	hom	-	1.1.1.3,2.2.1.6	ko:K00003,ko:K01653	ko00260,ko00270,ko00290,ko00300,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00270,map00290,map00300,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00017,M00018,M00019,M00570	R00006,R00014,R00226,R01773,R01775,R03050,R04672,R04673,R08648	RC00027,RC00087,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C,Homoserine_dh,MFS_1,NAD_binding_3
CMS3_k127_5605439_0	665571.STHERM_c17170	7.703e-244	766.0	COG0028@1|root,COG0028@2|Bacteria,2J5EZ@203691|Spirochaetes	203691|Spirochaetes	H	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_5605439_30	443143.GM18_0756	0.0003498	50.0	COG3117@1|root,COG3117@2|Bacteria,1NJ37@1224|Proteobacteria,42XKQ@68525|delta/epsilon subdivisions,2WSSC@28221|Deltaproteobacteria,43VDN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	-	-	-	-	-	-	-	-	-	LptC,OstA
CMS3_k127_5605439_28	1461694.ATO9_07370	1.688e-08	67.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,2PEC3@252301|Oceanicola	28211|Alphaproteobacteria	S	OstA-like protein	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
CMS3_k127_5605439_11	637390.AFOH01000106_gene71	1.905e-80	292.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,2NCI1@225057|Acidithiobacillales	225057|Acidithiobacillales	P	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
CMS3_k127_5605439_4	644282.Deba_1961	1.728e-143	477.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS3_k127_5605439_18	404589.Anae109_4310	2.505e-43	164.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2YVHR@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS3_k127_5605439_17	1347392.CCEZ01000049_gene1607	1.713e-50	184.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,36F8F@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CMS3_k127_5605439_14	56780.SYN_00941	4.23e-71	264.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2MQEB@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS3_k127_5605439_20	909663.KI867150_gene940	9.043e-34	136.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MQJY@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
CMS3_k127_5605439_27	481448.Minf_2250	3.795e-11	72.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,37GYW@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	PTS HPr component phosphorylation site	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS3_k127_5605439_3	247639.MGP2080_03105	1.058e-156	506.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1J4CX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_4967,iYL1228.KPN_03375	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS3_k127_5605439_16	118166.JH976537_gene2101	2.398e-53	204.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria,1H8UJ@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
CMS3_k127_5605439_26	1379270.AUXF01000004_gene3258	9.816e-12	79.0	COG1862@1|root,COG1862@2|Bacteria,1ZU5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS3_k127_5605439_7	526222.Desal_1636	3.785e-107	373.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2M865@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_5605439_12	1232410.KI421418_gene2299	1.671e-75	265.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_5605439_24	404589.Anae109_3692	8.38e-19	95.0	COG1664@1|root,COG1664@2|Bacteria,1RHS7@1224|Proteobacteria	1224|Proteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_5605439_29	1131269.AQVV01000010_gene2437	3.25e-08	59.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS3_k127_5644825_20	1041522.MCOL_V213465	3.985e-66	233.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,233NX@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS3_k127_5644825_6	1206737.BAGF01000042_gene2640	6.163e-120	392.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4FU0S@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5644825_1	557599.MKAN_03230	4.945e-208	663.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,23CXI@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
CMS3_k127_5644825_35	512565.AMIS_25840	5.372e-08	65.0	COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria	201174|Actinobacteria	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD,VanZ
CMS3_k127_5644825_40	1121413.JMKT01000001_gene1735	0.0006382	49.0	COG1030@1|root,COG1030@2|Bacteria,1NKSJ@1224|Proteobacteria,432IQ@68525|delta/epsilon subdivisions,2WXUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS3_k127_5644825_10	644282.Deba_1905	7.69e-108	379.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_5644825_9	1144275.COCOR_07939	1.982e-108	369.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2YUI8@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS3_k127_5644825_39	502025.Hoch_1796	0.0003992	52.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2YYZA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5644825_33	509635.N824_22215	3.192e-19	101.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_5644825_14	1120792.JAFV01000001_gene2548	2.633e-91	324.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,36XU4@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Thioesterase-like superfamily	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
CMS3_k127_5644825_2	502025.Hoch_6864	7.766e-202	665.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS3_k127_5644825_41	573370.DMR_02790	0.0006531	53.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_5644825_22	1282876.BAOK01000001_gene1313	2.898e-54	204.0	COG1595@1|root,COG1595@2|Bacteria,1R44W@1224|Proteobacteria,2U1R0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
CMS3_k127_5644825_32	1125971.ASJB01000022_gene6910	2.517e-28	132.0	COG3467@1|root,COG3467@2|Bacteria,2IIAS@201174|Actinobacteria,4E69S@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
CMS3_k127_5644825_17	243090.RB13317	5.795e-82	286.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Lipase_GDSL_2,PSCyt1,PSCyt2,PSD1,cNMP_binding
CMS3_k127_5644825_38	1410661.JNKW01000002_gene1550	0.0002503	54.0	COG1359@1|root,COG1359@2|Bacteria,1V8JS@1239|Firmicutes,24JGR@186801|Clostridia	186801|Clostridia	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_5644825_3	1313172.YM304_08640	5.621e-161	518.0	COG4638@1|root,COG4638@2|Bacteria,2GMB2@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_5644825_16	670307.HYPDE_29508	7.326e-87	304.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2VDGB@28211|Alphaproteobacteria,3N7P3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_5644825_5	398525.KB900701_gene7744	6.011e-121	397.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria,3K2VY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_5644825_21	1121861.KB899915_gene1789	3.146e-64	233.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2JPS5@204441|Rhodospirillales	204441|Rhodospirillales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_5644825_23	111781.Lepto7376_1322	2.107e-46	193.0	28K7U@1|root,2Z9VT@2|Bacteria,1G5J6@1117|Cyanobacteria,1HG8J@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5644825_13	903818.KI912268_gene2731	1.015e-96	336.0	COG0277@1|root,COG0277@2|Bacteria,3Y2YU@57723|Acidobacteria	57723|Acidobacteria	C	PFAM FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
CMS3_k127_5644825_27	288000.BBta_2182	4.422e-37	143.0	2DM0Y@1|root,318KY@2|Bacteria,1NM1E@1224|Proteobacteria,2UVRR@28211|Alphaproteobacteria,3K4TZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5644825_30	517418.Ctha_2407	4.056e-34	139.0	COG0400@1|root,COG0400@2|Bacteria,1FE1K@1090|Chlorobi	1090|Chlorobi	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS3_k127_5644825_28	1121378.KB899705_gene2544	3.422e-36	153.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS3_k127_5644825_11	502025.Hoch_5653	9.084e-108	354.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria,2Z364@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS3_k127_5644825_36	1172181.KB911699_gene1517	1.459e-06	62.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
CMS3_k127_5644825_7	247633.GP2143_13366	6.894e-114	377.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,1J5HH@118884|unclassified Gammaproteobacteria	2|Bacteria	S	aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5644825_31	337191.KTR9_3899	1.979e-33	140.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,4GBC9@85026|Gordoniaceae	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5644825_37	1168065.DOK_17840	3.047e-05	59.0	COG3291@1|root,COG3291@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria,1J7AT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5644825_15	247634.GPB2148_3291	1.195e-89	337.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5644825_25	572477.Alvin_1688	2.306e-40	151.0	COG2329@1|root,COG2329@2|Bacteria,1MZKW@1224|Proteobacteria,1S9N8@1236|Gammaproteobacteria,1WZ9S@135613|Chromatiales	135613|Chromatiales	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_5644825_24	749927.AMED_8462	4.945e-42	179.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4E1HT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_5644825_19	1370121.AUWS01000035_gene4499	1.365e-77	273.0	COG0604@1|root,COG0604@2|Bacteria,2IATU@201174|Actinobacteria,237C7@1762|Mycobacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5644825_26	251221.35213755	2.109e-38	152.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
CMS3_k127_5644825_8	1121918.ARWE01000001_gene1548	1.035e-112	393.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_5644825_29	290397.Adeh_0418	5.432e-35	154.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
CMS3_k127_5644825_12	1211815.CBYP010000060_gene3130	8.638e-104	348.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5644825_0	1173024.KI912153_gene315	0.0	1212.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1JIBX@1189|Stigonemataceae	1117|Cyanobacteria	E	Glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS3_k127_5644825_4	1248760.ANFZ01000014_gene2180	2.947e-142	477.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria,2K63F@204457|Sphingomonadales	204457|Sphingomonadales	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_5644825_18	82996.sch_13740	4.113e-80	280.0	COG0524@1|root,COG0524@2|Bacteria,1PDS9@1224|Proteobacteria,1RQE5@1236|Gammaproteobacteria,402TV@613|Serratia	1236|Gammaproteobacteria	G	pfkB family carbohydrate kinase	yegV	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_5670565_4	1226994.AMZB01000123_gene2924	2.647e-33	134.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YEI8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
CMS3_k127_5670565_0	247634.GPB2148_1155	8.413e-184	636.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J5AG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS3_k127_5670565_3	1333998.M2A_2548	1.139e-51	195.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,2UB9Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_5670565_2	316058.RPB_3209	3.227e-69	241.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,3JU3S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	MA20_32390	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_3,GST_N
CMS3_k127_5670565_1	1125863.JAFN01000001_gene2531	1.662e-169	542.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
CMS3_k127_5691955_6	1538295.JY96_08245	1.715e-71	259.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,2VIT3@28216|Betaproteobacteria,1KPF5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
CMS3_k127_5691955_15	273068.TTE1047	8.37e-06	55.0	COG1366@1|root,COG1366@2|Bacteria,1UGQT@1239|Firmicutes,24HHN@186801|Clostridia,42GB8@68295|Thermoanaerobacterales	186801|Clostridia	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
CMS3_k127_5691955_14	290397.Adeh_0260	1.46e-12	80.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_16
CMS3_k127_5691955_2	479434.Sthe_1357	1.597e-207	674.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,27YSI@189775|Thermomicrobia	189775|Thermomicrobia	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_5691955_7	1313172.YM304_06620	4.15e-51	209.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_5691955_12	1333998.M2A_1992	7.645e-35	148.0	COG1309@1|root,COG1309@2|Bacteria,1NB4W@1224|Proteobacteria,2UIGM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5691955_11	1192034.CAP_2430	5.806e-38	151.0	COG0746@1|root,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2X9X1@28221|Deltaproteobacteria,2YW7C@29|Myxococcales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_5691955_4	1298880.AUEV01000014_gene3851	3.883e-145	481.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_5691955_0	479435.Kfla_2117	0.0	1128.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DSZJ@85009|Propionibacteriales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_5691955_8	290397.Adeh_1270	7.026e-51	206.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2YUX0@29|Myxococcales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_5691955_16	314260.PB2503_04147	0.0002861	52.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	MA20_21995	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS3_k127_5691955_5	1121428.DESHY_110522___1	2.666e-134	476.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,260I5@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS3_k127_5691955_1	269799.Gmet_3219	2.903e-276	886.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,43U9W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS3_k127_5691955_3	1229780.BN381_210089	1.855e-155	513.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,3UWAM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS3_k127_5691955_9	443143.GM18_4228	2.702e-43	178.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,43UN0@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
CMS3_k127_5691955_10	1122919.KB905578_gene3252	3.895e-42	167.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,26QP8@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CMS3_k127_5691955_13	1047013.AQSP01000133_gene2131	6.891e-28	129.0	COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS3_k127_5711485_7	290397.Adeh_3328	0.0005255	52.0	COG3215@1|root,COG3215@2|Bacteria,1Q2S4@1224|Proteobacteria,43266@68525|delta/epsilon subdivisions,2WXR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
CMS3_k127_5711485_3	309801.trd_A0429	8.856e-92	332.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi,27Y50@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_5711485_0	497964.CfE428DRAFT_5927	4.303e-195	623.0	COG0029@1|root,COG0029@2|Bacteria,46SHQ@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_5711485_4	1232410.KI421413_gene544	2.98e-43	169.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,43SJX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4124)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
CMS3_k127_5711485_5	880072.Desac_2498	1.569e-39	156.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2MQNN@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_5711485_1	1379698.RBG1_1C00001G0637	1.116e-156	518.0	COG0677@1|root,COG0677@2|Bacteria,2NNQ1@2323|unclassified Bacteria	2|Bacteria	M	UDP binding domain	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_5711485_2	1380358.JADJ01000003_gene4569	2.849e-103	347.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,1S3RN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
CMS3_k127_5725679_3	1206741.BAFX01000024_gene8000	6.631e-12	68.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
CMS3_k127_5725679_2	517418.Ctha_0720	7.044e-23	105.0	COG2119@1|root,COG2119@2|Bacteria,1FFN7@1090|Chlorobi	1090|Chlorobi	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
CMS3_k127_5725679_1	1121904.ARBP01000005_gene4837	1.699e-47	190.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS3_k127_5725679_0	68219.JNXI01000020_gene8073	1.315e-61	222.0	COG0583@1|root,COG0583@2|Bacteria,2GNTF@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_5744506_14	332101.JIBU02000034_gene1763	5.717e-28	119.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,36EN8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
CMS3_k127_5744506_0	204669.Acid345_0997	2.351e-206	664.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS3_k127_5744506_2	635013.TherJR_0848	1.186e-199	647.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_5744506_7	278963.ATWD01000001_gene3530	7.649e-56	202.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_18,PRK
CMS3_k127_5744506_13	391600.ABRU01000056_gene452	2.953e-30	138.0	COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,2TV6N@28211|Alphaproteobacteria,2KFN9@204458|Caulobacterales	204458|Caulobacterales	S	L11 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PrmA
CMS3_k127_5744506_1	1415780.JPOG01000001_gene2508	5.385e-202	659.0	2DBUU@1|root,2ZB7U@2|Bacteria,1R8WF@1224|Proteobacteria,1SMN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS3_k127_5744506_9	1121939.L861_20355	1.68e-48	177.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria,1XKQJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_5744506_6	1121451.DESAM_22028	1.939e-56	221.0	COG1807@1|root,COG1807@2|Bacteria,1QQYT@1224|Proteobacteria,435NZ@68525|delta/epsilon subdivisions,2X02E@28221|Deltaproteobacteria,2M9ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5744506_4	635013.TherJR_0820	4.083e-97	338.0	COG1807@1|root,COG1807@2|Bacteria,1TTJ7@1239|Firmicutes,24ZXI@186801|Clostridia	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	-
CMS3_k127_5744506_5	118173.KB235914_gene3902	4.116e-74	278.0	COG1215@1|root,COG1215@2|Bacteria,1G5YB@1117|Cyanobacteria,1HB60@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5744506_12	926550.CLDAP_31220	7.445e-32	143.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
CMS3_k127_5744506_15	383372.Rcas_3345	2.246e-25	123.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5744506_8	765420.OSCT_1998	7.527e-53	206.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5744506_10	118163.Ple7327_4385	2.14e-46	187.0	COG0500@1|root,COG0500@2|Bacteria,1GQT2@1117|Cyanobacteria,3VNIA@52604|Pleurocapsales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_5744506_11	425104.Ssed_2991	9.546e-45	176.0	COG0463@1|root,COG0463@2|Bacteria,1QFUD@1224|Proteobacteria,1TD4S@1236|Gammaproteobacteria,2QDXE@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5744506_16	1297865.APJD01000047_gene4798	9.116e-05	55.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,2TTDM@28211|Alphaproteobacteria,3JS9U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_5744506_3	1121013.P873_10450	9.614e-116	382.0	COG1215@1|root,COG1215@2|Bacteria,1QUUY@1224|Proteobacteria,1RRKW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5772967_0	243231.GSU1772	1.099e-115	388.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,43TEQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_5772967_1	572477.Alvin_2709	3.041e-84	292.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS3_k127_5796308_1	1123279.ATUS01000001_gene1288	1.129e-147	490.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,1RRE0@1236|Gammaproteobacteria,1J5JG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	and related enzymes	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
CMS3_k127_5796308_6	391603.FBALC1_03182	1.409e-39	155.0	2EV7Q@1|root,33NNG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_5796308_8	903818.KI912269_gene229	2.396e-05	53.0	2C852@1|root,32YB2@2|Bacteria,3Y55S@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS3_k127_5796308_0	1121937.AUHJ01000003_gene3358	2.334e-160	537.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQ1C@1236|Gammaproteobacteria,466HP@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_5796308_4	1205680.CAKO01000004_gene3616	2.079e-83	284.0	28JPA@1|root,2Z9FC@2|Bacteria,1PN1F@1224|Proteobacteria,2TSKX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5796308_2	644282.Deba_0724	1.228e-118	409.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5796308_3	391625.PPSIR1_37774	2.149e-89	305.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,433GE@68525|delta/epsilon subdivisions,2WYHA@28221|Deltaproteobacteria,2YVI4@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_5796308_7	234267.Acid_1975	1.89e-37	160.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_5796308_5	247634.GPB2148_2582	7.427e-74	266.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_5797225_23	1206729.BAFZ01000159_gene6373	6.362e-12	68.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4FUUP@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_5797225_24	1041522.MCOL_V206380	4.076e-08	57.0	29W14@1|root,30HJI@2|Bacteria,2GYE5@201174|Actinobacteria,23BV8@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5797225_6	1206731.BAGB01000041_gene8934	6.168e-122	396.0	2FBIE@1|root,33PUQ@2|Bacteria,2I8W6@201174|Actinobacteria,4G1TM@85025|Nocardiaceae	201174|Actinobacteria	S	Spirocyclase AveC-like	-	-	-	-	-	-	-	-	-	-	-	-	AveC_like
CMS3_k127_5797225_11	443218.AS9A_4297	7.685e-106	368.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,233DK@1762|Mycobacteriaceae	201174|Actinobacteria	C	cytochrome p450	cyp123A3	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_5797225_8	298655.KI912266_gene638	1.023e-114	376.0	COG1028@1|root,COG1028@2|Bacteria,2I5P4@201174|Actinobacteria,4EX3G@85013|Frankiales	201174|Actinobacteria	IQ	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5797225_4	1299327.I546_2829	4.149e-140	455.0	2FBIE@1|root,343PQ@2|Bacteria,2GP5F@201174|Actinobacteria,236ND@1762|Mycobacteriaceae	201174|Actinobacteria	S	Spirocyclase AveC-like	-	-	-	-	-	-	-	-	-	-	-	-	AveC_like
CMS3_k127_5797225_5	1122247.C731_4543	2.84e-136	465.0	COG0714@1|root,COG0714@2|Bacteria,2GWNF@201174|Actinobacteria,232BM@1762|Mycobacteriaceae	201174|Actinobacteria	S	CbbQ NirQ NorQ C-terminal	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
CMS3_k127_5797225_0	1449048.JQKU01000009_gene697	1.503e-194	622.0	COG4548@1|root,COG4548@2|Bacteria,2GIYK@201174|Actinobacteria,234RV@1762|Mycobacteriaceae	201174|Actinobacteria	P	von willebrand factor type a	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_CoxE
CMS3_k127_5797225_1	525368.HMPREF0591_5056	5.38e-177	571.0	COG1309@1|root,COG1309@2|Bacteria,2GMWH@201174|Actinobacteria,234K1@1762|Mycobacteriaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5797225_3	1265310.CCBD010000038_gene2329	1.907e-143	469.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,233WB@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5797225_9	1242864.D187_004098	2.296e-111	375.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,438PG@68525|delta/epsilon subdivisions,2X3X6@28221|Deltaproteobacteria,2YXF3@29|Myxococcales	28221|Deltaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_5797225_14	880073.Calab_0209	3.913e-90	314.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	-	-	1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13	ko:K00123,ko:K00317,ko:K00528,ko:K09835	ko00630,ko00680,ko00906,ko01100,ko01110,ko01120,ko01200,map00630,map00680,map00906,map01100,map01110,map01120,map01200	M00097	R00519,R01588,R02511,R07512,R10159	RC00185,RC00556,RC00557,RC00732,RC01960,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4_20,NAD_binding_8,Oxidored_FMN,Pyr_redox_2
CMS3_k127_5797225_19	316067.Geob_1156	5.774e-52	187.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,437CT@68525|delta/epsilon subdivisions,2XA0U@28221|Deltaproteobacteria,43VKC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS3_k127_5797225_7	756272.Plabr_3432	2.134e-118	424.0	COG4260@1|root,COG4260@2|Bacteria,2IYIR@203682|Planctomycetes	203682|Planctomycetes	S	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339
CMS3_k127_5797225_20	391625.PPSIR1_00465	2.178e-31	138.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
CMS3_k127_5797225_2	448385.sce4447	1.177e-147	488.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_5797225_10	1232410.KI421412_gene98	5.405e-106	366.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,43RZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	zinc finger	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS3_k127_5797225_22	290397.Adeh_0718	1.869e-16	81.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS3_k127_5797225_13	1125863.JAFN01000001_gene1717	4.685e-91	321.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_5797225_16	443152.MDG893_03720	1.769e-67	247.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,464AA@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_5797225_17	1121428.DESHY_70025___1	1.335e-59	213.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,260M0@186807|Peptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_5797225_18	269796.Rru_A3597	7.713e-58	229.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2JPDI@204441|Rhodospirillales	204441|Rhodospirillales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS3_k127_5797225_12	1121918.ARWE01000001_gene2405	6.275e-93	336.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,43S7B@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Histidinol dehydrogenase	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS3_k127_5797225_15	1125863.JAFN01000001_gene1724	5.279e-71	255.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS3_k127_5797225_21	1254432.SCE1572_51305	8.631e-27	111.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2YTSK@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_584247_14	237368.SCABRO_00617	3.246e-29	123.0	COG1033@1|root,COG1033@2|Bacteria,2IYET@203682|Planctomycetes	203682|Planctomycetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_584247_12	1298880.AUEV01000007_gene4699	3.467e-40	157.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS3_k127_584247_13	768671.ThimaDRAFT_0960	4.883e-39	152.0	2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria,1THVW@1236|Gammaproteobacteria,1WZR5@135613|Chromatiales	135613|Chromatiales	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
CMS3_k127_584247_27	342451.SSP2101	7.846e-09	63.0	COG3238@1|root,COG3238@2|Bacteria,1V0FB@1239|Firmicutes,4HFG7@91061|Bacilli,4GXEN@90964|Staphylococcaceae	91061|Bacilli	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
CMS3_k127_584247_24	414684.RC1_1193	5.876e-11	71.0	COG0346@1|root,COG0346@2|Bacteria,1PK2J@1224|Proteobacteria,2UMZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_584247_23	1121381.JNIV01000054_gene610	5.337e-12	72.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180,PadR
CMS3_k127_584247_28	1120950.KB892750_gene6815	2.064e-06	59.0	COG1266@1|root,COG1266@2|Bacteria,2IS6T@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_584247_21	1306174.JODP01000001_gene5270	1.796e-14	81.0	COG1309@1|root,COG1309@2|Bacteria,2GJVD@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_584247_11	1280953.HOC_08954	1.054e-44	175.0	COG3791@1|root,COG3791@2|Bacteria,1REMP@1224|Proteobacteria,2U61P@28211|Alphaproteobacteria,440BA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_584247_8	1120950.KB892776_gene788	6.713e-51	188.0	COG0500@1|root,COG2226@2|Bacteria,2I636@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_584247_3	1229780.BN381_130222	2.671e-116	381.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_584247_9	1122247.C731_0984	3.853e-50	188.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_584247_0	247634.GPB2148_1760	1.92e-131	429.0	2DB8I@1|root,2Z7RY@2|Bacteria,1MY4M@1224|Proteobacteria,1SPR1@1236|Gammaproteobacteria,1JAR1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584247_17	639030.JHVA01000001_gene2233	2.693e-20	102.0	2EAZB@1|root,33507@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584247_7	1089551.KE386572_gene443	4.824e-53	211.0	COG0265@1|root,COG0265@2|Bacteria,1NCF1@1224|Proteobacteria,2UT5J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_584247_2	1121937.AUHJ01000001_gene748	7.231e-126	413.0	COG2141@1|root,COG2141@2|Bacteria,1R6NN@1224|Proteobacteria	1224|Proteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_584247_4	1122970.AUHC01000011_gene2715	1.793e-76	264.0	COG1024@1|root,COG1024@2|Bacteria,1N4N7@1224|Proteobacteria,2TS6T@28211|Alphaproteobacteria,2K1V0@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_584247_16	2340.JV46_12030	2.886e-26	117.0	COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,1S793@1236|Gammaproteobacteria,1JAI2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	Z012_10940	-	-	-	-	-	-	-	-	-	-	-	SIMPL
CMS3_k127_584247_15	290397.Adeh_0169	1.883e-27	123.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_0169|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584247_19	1122604.JONR01000001_gene1735	4.96e-17	87.0	2FAF9@1|root,342PH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584247_18	883126.HMPREF9710_04126	4.697e-20	104.0	COG2890@1|root,COG2890@2|Bacteria,1R6XD@1224|Proteobacteria,2VZQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	MTS
CMS3_k127_584247_1	234267.Acid_5615	1.121e-126	421.0	COG0443@1|root,COG0443@2|Bacteria,3Y3QN@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CMS3_k127_584247_6	402881.Plav_2713	6.84e-54	208.0	2EXDM@1|root,33QQ7@2|Bacteria,1NTQ6@1224|Proteobacteria,2UQVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584247_5	1177181.T9A_02505	1.171e-55	221.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,1RQYS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_584247_26	479434.Sthe_2534	2.131e-09	71.0	COG2373@1|root,COG3420@1|root,COG2373@2|Bacteria,COG3420@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K13735,ko:K21449	ko05100,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	Big_1,DUF3494,IAT_beta,Invasin_D3
CMS3_k127_584247_10	483219.LILAB_24495	1.731e-46	187.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2YV6T@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
CMS3_k127_5871952_23	1469557.JSWF01000036_gene808	2.465e-13	85.0	COG3209@1|root,COG3291@1|root,COG3897@1|root,COG4886@1|root,COG5306@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3897@2|Bacteria,COG4886@2|Bacteria,COG5306@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	htaA	-	3.4.21.72	ko:K01347,ko:K03561,ko:K12287	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.A.30.2.1,1.B.12.3	-	-	CHU_C,DUF2341,HtaA,LRR_5,Laminin_G_3,MotA_ExbB
CMS3_k127_5871952_0	1278073.MYSTI_07874	4.221e-312	990.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria,439FZ@68525|delta/epsilon subdivisions,2X4RS@28221|Deltaproteobacteria,2YZGC@29|Myxococcales	28221|Deltaproteobacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5871952_6	56107.Cylst_2613	1.002e-78	279.0	COG1520@1|root,COG1520@2|Bacteria,1GDEQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS3_k127_5871952_18	1123257.AUFV01000003_gene1123	1.489e-25	116.0	COG0346@1|root,COG0346@2|Bacteria,1RIBY@1224|Proteobacteria,1T0C1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_5871952_4	1463858.JOHR01000007_gene811	3.774e-93	315.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria	201174|Actinobacteria	Q	taurine catabolism dioxygenase	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_5871952_15	1282876.BAOK01000002_gene880	2.131e-42	179.0	COG3686@1|root,COG3686@2|Bacteria,1RAEH@1224|Proteobacteria,2U5JJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MAPEG family	MA20_30600	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS3_k127_5871952_7	1218076.BAYB01000027_gene4546	8.577e-72	247.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2VQ52@28216|Betaproteobacteria,1K1WB@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF488,UDG
CMS3_k127_5871952_10	1201293.AKXQ01000019_gene1124	2.18e-54	202.0	COG3474@1|root,COG3474@2|Bacteria,1RI3E@1224|Proteobacteria,1S8E1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
CMS3_k127_5871952_13	1254432.SCE1572_05510	1.487e-49	189.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5871952_17	1300345.LF41_3094	1.166e-25	113.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavin and coenzyme A sequestration protein dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS3_k127_5871952_27	67267.JNXT01000018_gene7849	7.013e-07	61.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_6,Acetyltransf_7,Acetyltransf_9
CMS3_k127_5871952_2	237727.NAP1_06200	1.932e-172	568.0	COG1404@1|root,COG1404@2|Bacteria,1RD7Y@1224|Proteobacteria,2U7GD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_5871952_29	1388763.O165_021240	4.701e-05	55.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1YVCC@136845|Pseudomonas putida group	1236|Gammaproteobacteria	U	type IV pilus secretin PilQ	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS3_k127_5871952_26	234267.Acid_1873	1.549e-09	71.0	2DV73@1|root,33UF8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5871952_16	396588.Tgr7_3139	2.413e-29	131.0	COG5295@1|root,COG5295@2|Bacteria,1N8QZ@1224|Proteobacteria	1224|Proteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5871952_11	797114.C475_12537	3.057e-54	219.0	COG3119@1|root,arCOG02785@2157|Archaea,2XV54@28890|Euryarchaeota,23UWR@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5871952_14	1396418.BATQ01000117_gene4548	1.001e-47	198.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5871952_1	42256.RradSPS_0425	7.48e-278	912.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
CMS3_k127_5871952_24	1206743.BAGM01000123_gene1874	3.778e-12	79.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4FVAI@85025|Nocardiaceae	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
CMS3_k127_5871952_12	378806.STAUR_2713	7.399e-52	207.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_5871952_9	246197.MXAN_5815	8.628e-58	214.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria	1224|Proteobacteria	D	Chromosome Partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_5871952_5	450851.PHZ_c3271	3.558e-86	293.0	COG0625@1|root,COG0625@2|Bacteria,1NUET@1224|Proteobacteria,2TRGC@28211|Alphaproteobacteria,2KJCX@204458|Caulobacterales	204458|Caulobacterales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
CMS3_k127_5871952_25	1120966.AUBU01000001_gene1101	6.438e-10	64.0	2DNNF@1|root,32Y92@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5871952_30	558173.CDOO_12145	0.0004876	49.0	2DNW5@1|root,32ZGI@2|Bacteria,2IQ5T@201174|Actinobacteria,22P4B@1653|Corynebacteriaceae	201174|Actinobacteria	S	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
CMS3_k127_5871952_21	1206720.BAFQ01000296_gene6644	4.947e-19	101.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria,4FUGY@85025|Nocardiaceae	201174|Actinobacteria	S	Protein involved in polyketide synthase activity and antibiotic biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS3_k127_5871952_8	580332.Slit_1327	4.233e-60	231.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria,44WPK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
CMS3_k127_5871952_19	106370.Francci3_2153	9.152e-25	122.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_5871952_3	267608.RSp1667	8.955e-146	476.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K375@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	zraR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5871952_20	671143.DAMO_0983	2.723e-20	100.0	COG0589@1|root,COG0589@2|Bacteria,2NPUM@2323|unclassified Bacteria	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5874535_5	670487.Ocepr_0311	9.691e-22	96.0	COG1832@1|root,COG1832@2|Bacteria,1WJSJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS3_k127_5874535_6	1123320.KB889697_gene9041	1.173e-05	56.0	COG2761@1|root,COG2761@2|Bacteria,2GNBC@201174|Actinobacteria	201174|Actinobacteria	Q	Dithiol-disulfide isomerase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_5874535_2	69328.PVLB_22190	1.271e-35	148.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Translation Initiation Factor	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
CMS3_k127_5874535_1	1125863.JAFN01000001_gene685	1.079e-62	233.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5874535_3	247490.KSU1_B0345	7.631e-35	154.0	COG1807@1|root,COG1807@2|Bacteria,2IZ8J@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 39	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
CMS3_k127_5874535_0	595460.RRSWK_06726	1.087e-169	578.0	COG0372@1|root,COG0372@2|Bacteria,2IYFN@203682|Planctomycetes	203682|Planctomycetes	H	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_587881_4	1382359.JIAL01000001_gene2644	1.189e-36	153.0	COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS3_k127_587881_1	215803.DB30_4304	9.945e-99	345.0	COG1216@1|root,COG4976@1|root,COG1216@2|Bacteria,COG4976@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
CMS3_k127_587881_3	195253.Syn6312_3280	8.042e-57	213.0	2DV15@1|root,33TGW@2|Bacteria,1GC8U@1117|Cyanobacteria,1H0PG@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_587881_0	247634.GPB2148_1166	6.092e-150	481.0	COG0657@1|root,COG0657@2|Bacteria,1NRN8@1224|Proteobacteria,1SK0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_587881_2	344747.PM8797T_03069	8.749e-61	229.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Sulfatase
CMS3_k127_5897887_35	1121438.JNJA01000008_gene3904	0.0001081	53.0	295MH@1|root,2ZSYX@2|Bacteria,1PBGZ@1224|Proteobacteria,43E9M@68525|delta/epsilon subdivisions,2X039@28221|Deltaproteobacteria,2MA97@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_36	479434.Sthe_2271	0.0004063	53.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5897887_15	317619.ANKN01000049_gene2828	3.133e-49	187.0	2DG8R@1|root,2ZUYV@2|Bacteria,1G8JI@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_5897887_14	646529.Desaci_4276	2.935e-49	189.0	COG3551@1|root,COG3551@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Sulfotransfer_3
CMS3_k127_5897887_24	502025.Hoch_2273	2.078e-22	111.0	COG3793@1|root,COG3793@2|Bacteria	2|Bacteria	P	PFAM Mo-dependent nitrogenase	-	-	-	ko:K05793	-	-	-	-	ko00000	-	-	-	TerB
CMS3_k127_5897887_22	1288963.ADIS_1088	1.164e-29	129.0	COG3394@1|root,COG3394@2|Bacteria,4NKJ2@976|Bacteroidetes,47NPC@768503|Cytophagia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS3_k127_5897887_4	1238182.C882_3937	1.346e-131	453.0	COG0841@1|root,COG0841@2|Bacteria,1R2RN@1224|Proteobacteria,2TZQG@28211|Alphaproteobacteria,2JZ4G@204441|Rhodospirillales	204441|Rhodospirillales	V	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_5897887_2	402881.Plav_0360	2.419e-208	670.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,1JQ85@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS3_k127_5897887_30	1532558.JL39_02590	2.485e-11	71.0	2ERSV@1|root,33JC2@2|Bacteria,1REGE@1224|Proteobacteria,2U5F2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_1	331869.BAL199_16228	1.596e-251	785.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,4BPZW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	GMC oxidoreductase	MA20_17575	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CMS3_k127_5897887_26	439235.Dalk_0190	6.421e-20	103.0	COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5897887_7	189425.PGRAT_15260	2.971e-82	282.0	COG1131@1|root,COG1131@2|Bacteria,1TRNT@1239|Firmicutes,4HB3P@91061|Bacilli,26QX1@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K16907	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5897887_32	1125718.HMPREF1318_1367	2.335e-06	60.0	COG1668@1|root,COG1668@2|Bacteria,2H8P2@201174|Actinobacteria,4D5QR@85005|Actinomycetales	201174|Actinobacteria	CP	transmembrane transport	-	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_5897887_29	586413.CCDL010000001_gene419	3.115e-13	82.0	COG0474@1|root,COG0474@2|Bacteria,1UIM5@1239|Firmicutes,4HMFI@91061|Bacilli,23M01@182709|Oceanobacillus	91061|Bacilli	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_23	1205680.CAKO01000002_gene2792	8.533e-25	120.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,2TUYH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_16	1267535.KB906767_gene5001	7.897e-47	196.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_5897887_19	42256.RradSPS_1688	1.847e-41	179.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_11	1121939.L861_13660	1.472e-66	261.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
CMS3_k127_5897887_3	1380390.JIAT01000001_gene5055	2.569e-196	642.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CRFS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.20	ko:K07749,ko:K18313	-	-	R10640,R10641	RC00014	ko00000,ko01000	-	-	-	CoA_transf_3
CMS3_k127_5897887_0	1254432.SCE1572_00900	0.0	1161.0	COG2192@1|root,COG2755@1|root,COG2192@2|Bacteria,COG2755@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2YYSN@29|Myxococcales	28221|Deltaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_5897887_13	438753.AZC_1508	1.696e-53	218.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2TTHZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_9	641107.CDLVIII_2733	3.378e-73	261.0	COG2348@1|root,COG2348@2|Bacteria,1V67I@1239|Firmicutes,24FI6@186801|Clostridia,36HXS@31979|Clostridiaceae	186801|Clostridia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_5897887_28	700015.Corgl_1125	4.066e-14	85.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4CUZK@84998|Coriobacteriia	84998|Coriobacteriia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_5897887_20	765911.Thivi_4064	9.908e-35	154.0	COG0438@1|root,COG0438@2|Bacteria,1R8BR@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5897887_10	1254432.SCE1572_04735	6.927e-72	270.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,42SVA@68525|delta/epsilon subdivisions,2WPFH@28221|Deltaproteobacteria,2Z1X4@29|Myxococcales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_5897887_18	1205680.CAKO01000002_gene2221	4.899e-42	171.0	2DBSD@1|root,2ZARI@2|Bacteria,1MX0F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_17	1205680.CAKO01000002_gene2220	2.381e-42	158.0	2BRR9@1|root,32KR1@2|Bacteria,1P9A5@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5897887_12	1353529.M899_2851	2.397e-55	200.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,42T5R@68525|delta/epsilon subdivisions,2WX1F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def_2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS3_k127_5897887_5	105425.BBPL01000001_gene5970	4.673e-124	428.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria,2NNER@228398|Streptacidiphilus	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
CMS3_k127_5897887_33	215803.DB30_7466	5.023e-06	60.0	COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria,42QWX@68525|delta/epsilon subdivisions,2WN80@28221|Deltaproteobacteria,2YXRS@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
CMS3_k127_5897887_21	243231.GSU2510	4.159e-32	146.0	COG2227@1|root,COG2227@2|Bacteria,1RHSX@1224|Proteobacteria,42TZQ@68525|delta/epsilon subdivisions,2WR01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_5897887_25	448385.sce1096	2.713e-21	112.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_5897887_31	1121451.DESAM_22028	3.015e-11	77.0	COG1807@1|root,COG1807@2|Bacteria,1QQYT@1224|Proteobacteria,435NZ@68525|delta/epsilon subdivisions,2X02E@28221|Deltaproteobacteria,2M9ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5897887_6	243231.GSU1789	5.058e-84	284.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_5897887_8	861299.J421_3119	2.54e-80	280.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_5897887_34	1121451.DESAM_22028	1.599e-05	60.0	COG1807@1|root,COG1807@2|Bacteria,1QQYT@1224|Proteobacteria,435NZ@68525|delta/epsilon subdivisions,2X02E@28221|Deltaproteobacteria,2M9ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6030485_1	1282876.BAOK01000001_gene3450	2.625e-132	440.0	COG1752@1|root,COG1752@2|Bacteria,1N5SK@1224|Proteobacteria,2UP09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF3336)	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	DUF3336,Patatin
CMS3_k127_6030485_2	67373.JOBF01000001_gene6000	1.113e-93	326.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_6030485_5	1201288.M900_1736	2.528e-12	79.0	COG4264@1|root,COG4264@2|Bacteria,1NS11@1224|Proteobacteria,42Z7Q@68525|delta/epsilon subdivisions,2MTKF@213481|Bdellovibrionales,2WUGR@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	IucA IucC family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6030485_3	314275.MADE_1015305	7.931e-74	263.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,46641@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_6030485_0	396588.Tgr7_0704	3.014e-321	1028.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS3_k127_6030485_4	713586.KB900536_gene1447	8.675e-73	258.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WWA8@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS3_k127_6037694_2	269797.Mbar_A0368	6.969e-09	69.0	COG1287@1|root,arCOG02043@2157|Archaea,2XX8Q@28890|Euryarchaeota,2NADZ@224756|Methanomicrobia	224756|Methanomicrobia	M	Oligosaccharyl transferase STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
CMS3_k127_6037694_0	529818.AMSG_11506T0	2.744e-86	313.0	29QRV@1|root,2RX97@2759|Eukaryota	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_6037694_3	667014.Thein_0527	7.081e-09	66.0	COG5616@1|root,COG5616@2|Bacteria,2GHPI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6037694_1	483219.LILAB_34655	3.718e-46	185.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WME7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	hsfB	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_6042472_4	269482.Bcep1808_5583	1.518e-69	243.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VH34@28216|Betaproteobacteria,1KFIP@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
CMS3_k127_6042472_3	452637.Oter_3914	1.271e-96	338.0	COG0531@1|root,COG0531@2|Bacteria,46SPF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_6042472_0	1415780.JPOG01000001_gene1380	3.05e-164	530.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1X49S@135614|Xanthomonadales	135614|Xanthomonadales	E	aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_6042472_2	1125863.JAFN01000001_gene1005	1.399e-143	474.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS3_k127_6042472_1	867845.KI911784_gene674	5.876e-147	473.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_6055718_5	1500893.JQNB01000001_gene234	1.379e-15	80.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1X3WP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_6055718_1	404589.Anae109_4464	9.203e-62	231.0	COG0840@1|root,COG0840@2|Bacteria,1RA20@1224|Proteobacteria,42QNV@68525|delta/epsilon subdivisions,2WMT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
CMS3_k127_6055718_3	309803.CTN_1885	1.653e-39	150.0	COG2201@1|root,COG2201@2|Bacteria,2GCZV@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_6055718_6	443143.GM18_3731	4.688e-11	73.0	COG0643@1|root,COG0643@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria,43T85@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
CMS3_k127_6055718_0	404589.Anae109_4461	8.31e-74	271.0	COG0643@1|root,COG0643@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
CMS3_k127_6055718_4	379066.GAU_1407	2.012e-16	87.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
CMS3_k127_6055718_2	59374.Fisuc_0881	1.417e-58	212.0	COG2738@1|root,COG2738@2|Bacteria	2|Bacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS3_k127_6057062_1	929703.KE386491_gene2146	1.556e-161	522.0	COG1488@1|root,COG1488@2|Bacteria,4NGVU@976|Bacteroidetes,47PMM@768503|Cytophagia	976|Bacteroidetes	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	nadV	-	2.4.2.12	ko:K03462	ko00760,ko01100,ko04621,map00760,map01100,map04621	-	R01271	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
CMS3_k127_6057062_0	1121937.AUHJ01000005_gene2149	1.347e-214	692.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,464Z2@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_6057062_6	1121405.dsmv_2761	1.255e-21	106.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6057062_2	571166.KI421510_gene180	4.797e-146	474.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_06720	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6057062_4	479432.Sros_6660	1.969e-44	176.0	2BXSN@1|root,2ZAB3@2|Bacteria,2I1VJ@201174|Actinobacteria,4EPCA@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
CMS3_k127_6057062_3	215803.DB30_7225	1.739e-81	287.0	COG0834@1|root,COG0834@2|Bacteria,1PEIW@1224|Proteobacteria,432E1@68525|delta/epsilon subdivisions,2WYEP@28221|Deltaproteobacteria,2YXCY@29|Myxococcales	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	4.2.1.51,4.2.1.91	ko:K01713	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	SBP_bac_3
CMS3_k127_6057062_5	935261.JAGL01000014_gene3632	7.586e-40	165.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_6061225_9	1223542.GM1_042_00190	9.346e-20	93.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4GARK@85026|Gordoniaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_6061225_1	570268.ANBB01000047_gene3878	1.668e-79	281.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,4EFZS@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_6061225_12	1123258.AQXZ01000019_gene3370	2.37e-10	72.0	COG0500@1|root,COG2226@2|Bacteria,2ICJD@201174|Actinobacteria,4FVCF@85025|Nocardiaceae	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_6061225_10	1121413.JMKT01000015_gene291	1.57e-17	96.0	28MH4@1|root,2ZAU2@2|Bacteria,1P8YP@1224|Proteobacteria,42MQK@68525|delta/epsilon subdivisions,2WKCY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6061225_8	930166.CD58_23885	2.394e-24	110.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S2RH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
CMS3_k127_6061225_4	1125863.JAFN01000001_gene3277	3.08e-70	260.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_3
CMS3_k127_6061225_11	740709.A10D4_11114	1.725e-16	90.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2QGSN@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6061225_0	264462.Bd3432	1.744e-145	480.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2MSND@213481|Bdellovibrionales,2WIT0@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	two component, sigma54 specific, transcriptional regulator, Fis family	fgrM	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6061225_3	1201290.M902_0431	1.262e-72	259.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,42QQ8@68525|delta/epsilon subdivisions,2MSNG@213481|Bdellovibrionales,2WMX3@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_6061225_5	1382359.JIAL01000001_gene2071	2.425e-49	188.0	COG0631@1|root,COG0631@2|Bacteria,3Y4I5@57723|Acidobacteria,2JJA7@204432|Acidobacteriia	204432|Acidobacteriia	T	Protein phosphatase 2C	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_6061225_6	404589.Anae109_1476	6.922e-47	191.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_6061225_2	243231.GSU1936	1.879e-79	278.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,43T21@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
CMS3_k127_6061225_7	1144275.COCOR_03821	1.571e-35	151.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_6084312_15	926569.ANT_24640	7.992e-07	62.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_6084312_7	706587.Desti_0925	8.415e-62	241.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_6084312_3	269799.Gmet_1502	2.342e-110	381.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_6084312_14	195105.CN97_02260	1.036e-30	138.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2TUKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS3_k127_6084312_9	639030.JHVA01000001_gene3243	1.625e-50	205.0	COG1269@1|root,COG1269@2|Bacteria,3Y7E1@57723|Acidobacteria,2JKI6@204432|Acidobacteriia	204432|Acidobacteriia	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS3_k127_6084312_2	1278073.MYSTI_01143	5.686e-124	414.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,2YVAN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CMS3_k127_6084312_1	1125863.JAFN01000001_gene746	7.444e-142	467.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6084312_10	1121413.JMKT01000015_gene250	4.078e-40	156.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42SP0@68525|delta/epsilon subdivisions,2WNYF@28221|Deltaproteobacteria,2MAXP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS3_k127_6084312_11	933262.AXAM01000037_gene884	6.34e-39	165.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42M2D@68525|delta/epsilon subdivisions,2WJU6@28221|Deltaproteobacteria,2MIV6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
CMS3_k127_6084312_5	1121405.dsmv_2190	2.622e-71	252.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,2MIMN@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Peptidoglycan-binding domain 1 protein	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
CMS3_k127_6084312_13	171693.BN988_02205	6.988e-35	146.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,23JDM@182709|Oceanobacillus	91061|Bacilli	D	NUBPL iron-transfer P-loop NTPase	ywqD	-	2.7.10.2	ko:K00903	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,ParA
CMS3_k127_6084312_8	1111479.AXAR01000012_gene1400	7.45e-53	210.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,277YR@186823|Alicyclobacillaceae	91061|Bacilli	M	Glycosyl transferase family 4	llm	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS3_k127_6084312_4	1123371.ATXH01000019_gene615	2.648e-92	329.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_6084312_0	573413.Spirs_4274	2.808e-157	525.0	COG1004@1|root,COG1004@2|Bacteria,2J6SD@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_6084312_6	518766.Rmar_0883	3.146e-71	255.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1FJ2I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_6084312_12	880073.Calab_3274	3.093e-36	147.0	COG0664@1|root,COG0664@2|Bacteria,2NPVK@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_6089367_6	740709.A10D4_05217	9.991e-104	351.0	COG0769@1|root,COG0769@2|Bacteria,1QYFB@1224|Proteobacteria,1T3Q5@1236|Gammaproteobacteria,2QGQ5@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Mur ligase middle domain	-	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_M
CMS3_k127_6089367_17	459349.CLOAM0865	2.079e-20	98.0	29EG8@1|root,334DW@2|Bacteria,2NPTE@2323|unclassified Bacteria	2|Bacteria	S	Capsule biosynthesis CapC	capC	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
CMS3_k127_6089367_13	740709.A10D4_05207	4.231e-65	236.0	28JNG@1|root,2Z9ES@2|Bacteria,1N32V@1224|Proteobacteria,1S9AH@1236|Gammaproteobacteria,2QGP2@267893|Idiomarinaceae	1236|Gammaproteobacteria	-	-	pgsW	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6089367_2	247633.GP2143_01710	1.634e-115	387.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS3_k127_6089367_5	1157490.EL26_00620	6.691e-105	362.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,278JH@186823|Alicyclobacillaceae	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS3_k127_6089367_12	402881.Plav_3102	3.196e-71	250.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2TTDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS3_k127_6089367_9	748247.AZKH_2298	2.063e-87	295.0	COG3828@1|root,COG3828@2|Bacteria,1QWCA@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	MA20_14010	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS3_k127_6089367_10	247634.GPB2148_2989	9.729e-86	291.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,1S08S@1236|Gammaproteobacteria,1J842@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CMS3_k127_6089367_4	247634.GPB2148_3101	7.041e-109	366.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_6089367_3	1382356.JQMP01000003_gene1612	1.042e-113	381.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi,27XJB@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
CMS3_k127_6089367_1	1111479.AXAR01000018_gene2552	1.249e-128	419.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_6089367_16	1120972.AUMH01000005_gene900	2.026e-20	105.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_6089367_18	570268.ANBB01000055_gene4875	1.199e-12	80.0	COG2267@1|root,COG2267@2|Bacteria,2I3KS@201174|Actinobacteria,4ER5T@85012|Streptosporangiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_6089367_15	1123269.NX02_14920	9.192e-37	160.0	COG0477@1|root,COG2814@2|Bacteria,1NAK9@1224|Proteobacteria,2UHZU@28211|Alphaproteobacteria,2K2IR@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1
CMS3_k127_6089367_0	1380394.JADL01000002_gene1376	1.891e-164	543.0	COG1415@1|root,COG1415@2|Bacteria,1QQ3V@1224|Proteobacteria,2TRG5@28211|Alphaproteobacteria,2JRBJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
CMS3_k127_6089367_7	1123504.JQKD01000022_gene154	2.642e-102	364.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2W2C8@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_6089367_19	290397.Adeh_4035	4.781e-06	60.0	COG2834@1|root,COG2834@2|Bacteria,1NMTC@1224|Proteobacteria,42XC3@68525|delta/epsilon subdivisions,2WT97@28221|Deltaproteobacteria,2YWF6@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
CMS3_k127_6089367_14	439235.Dalk_0133	6.053e-46	188.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MIEU@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
CMS3_k127_6089367_11	237368.SCABRO_01007	3.333e-77	281.0	COG0529@1|root,COG0529@2|Bacteria,2IYUQ@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS3_k127_6089367_8	1316936.K678_08314	7.689e-97	325.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2JPHR@204441|Rhodospirillales	204441|Rhodospirillales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_6121975_6	502025.Hoch_5380	9.965e-84	288.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2YUUC@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6121975_1	768671.ThimaDRAFT_3759	1.025e-223	741.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WX0W@135613|Chromatiales	135613|Chromatiales	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_6121975_12	1049564.TevJSym_al00430	3.54e-14	88.0	2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria,1S7HH@1236|Gammaproteobacteria,1J70P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS3_k127_6121975_11	46429.BV95_01703	5.809e-17	94.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2TUKE@28211|Alphaproteobacteria,2K377@204457|Sphingomonadales	204457|Sphingomonadales	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS3_k127_6121975_3	886293.Sinac_7119	5.777e-108	385.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_6121975_2	886293.Sinac_7119	3.506e-137	460.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_6121975_8	1385935.N836_33115	1.554e-67	248.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
CMS3_k127_6121975_13	1128421.JAGA01000003_gene3091	3.45e-10	75.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_6121975_9	575540.Isop_3500	5.399e-32	144.0	COG1807@1|root,COG1807@2|Bacteria,2J28Z@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6121975_5	710421.Mycch_0546	3.366e-88	303.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,23D32@1762|Mycobacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,F420H2_quin_red
CMS3_k127_6121975_10	653733.Selin_2098	7.061e-21	105.0	COG0457@1|root,COG0457@2|Bacteria	653733.Selin_2098|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6121975_4	1382306.JNIM01000001_gene573	5.348e-95	327.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	hicd	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85,1.1.1.87	ko:K00052,ko:K05824	ko00290,ko00300,ko00660,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R00994,R01934,R01936,R04426,R04862,R10052	RC00084,RC00114,RC00417,RC00626,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_6121975_7	1168065.DOK_03853	4.749e-83	288.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,1SZG6@1236|Gammaproteobacteria,1J5W7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_6121975_0	335543.Sfum_3516	4.744e-240	760.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MQTV@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
CMS3_k127_6125727_6	331869.BAL199_28445	2.885e-45	165.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,4BPGN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	HflC and HflK could regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_6125727_0	1161401.ASJA01000013_gene767	1.397e-149	482.0	COG0701@1|root,COG0701@2|Bacteria,1NC9F@1224|Proteobacteria,2U1D0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS3_k127_6125727_2	1238182.C882_1154	2.332e-119	401.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2JQVG@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_6125727_3	443143.GM18_1190	1.422e-74	268.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,43V13@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
CMS3_k127_6125727_1	1125863.JAFN01000001_gene1933	4.078e-128	451.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS3_k127_6125727_4	671143.DAMO_0325	5.65e-70	265.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
CMS3_k127_6125727_5	867903.ThesuDRAFT_00086	4.225e-56	222.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WCFS@538999|Clostridiales incertae sedis	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
CMS3_k127_6149193_3	756272.Plabr_2351	1.335e-68	239.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_6149193_7	1101190.ARWB01000001_gene3005	1.16e-10	72.0	2EJQP@1|root,33DFH@2|Bacteria,1NI6C@1224|Proteobacteria,2UMF9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HIPIP
CMS3_k127_6149193_6	1123279.ATUS01000001_gene1161	2.004e-49	182.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,1J6CI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_6149193_5	1121434.AULY01000009_gene1913	1.361e-50	188.0	COG0569@1|root,COG0569@2|Bacteria,1RDDX@1224|Proteobacteria,436KP@68525|delta/epsilon subdivisions,2X9JW@28221|Deltaproteobacteria,2MEF0@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
CMS3_k127_6149193_1	1232410.KI421421_gene3337	5.898e-107	364.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42YBV@68525|delta/epsilon subdivisions,2WTTU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
CMS3_k127_6149193_2	105559.Nwat_0093	1.394e-104	349.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1WYFE@135613|Chromatiales	135613|Chromatiales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS3_k127_6149193_4	1278073.MYSTI_07775	1.065e-67	239.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,42PC4@68525|delta/epsilon subdivisions,2WMG6@28221|Deltaproteobacteria,2YXXU@29|Myxococcales	28221|Deltaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS3_k127_6149193_0	1380394.JADL01000003_gene4757	1.158e-138	484.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2TU9N@28211|Alphaproteobacteria,2JSM5@204441|Rhodospirillales	204441|Rhodospirillales	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS3_k127_6172231_2	1434325.AZQN01000010_gene3949	3.301e-22	98.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47KF6@768503|Cytophagia	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6172231_1	880073.Calab_2471	1.762e-33	143.0	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
CMS3_k127_6172231_0	1125863.JAFN01000001_gene2144	3.172e-62	234.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	transport system involved in gliding motility, auxiliary	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_6174123_35	1173027.Mic7113_2938	3.434e-69	265.0	COG0654@1|root,COG0654@2|Bacteria,1G2G8@1117|Cyanobacteria,1HHEF@1150|Oscillatoriales	1117|Cyanobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_6174123_71	479434.Sthe_1762	3.905e-15	89.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6174123_34	146922.JOFU01000007_gene6102	1.76e-69	256.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS3_k127_6174123_7	247633.GP2143_13341	1.376e-160	548.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1J90Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Aldo/keto reductase family	yajO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_6174123_20	626418.bglu_2g13370	2.373e-99	360.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2VMAU@28216|Betaproteobacteria,1K3SY@119060|Burkholderiaceae	28216|Betaproteobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	ptpA	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_6174123_62	443143.GM18_0564	1.21e-28	134.0	2C1C3@1|root,32R8E@2|Bacteria,1RIRN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6174123_26	1157635.KB892017_gene1657	1.429e-81	296.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6174123_45	1030157.AFMP01000009_gene3653	9.72e-48	187.0	COG1024@1|root,COG1024@2|Bacteria,1R9U5@1224|Proteobacteria,2V7VT@28211|Alphaproteobacteria,2K9ZY@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_6174123_8	679197.HMPREF9336_01932	9.794e-135	441.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	ltp1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_6174123_59	399795.CtesDRAFT_PD0907	2.262e-29	125.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2VXA4@28216|Betaproteobacteria,4AFID@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_6174123_1	710686.Mycsm_00030	1.408e-275	871.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,233RN@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_6174123_56	1396141.BATP01000058_gene1970	3.364e-32	141.0	COG0558@1|root,COG0558@2|Bacteria,46VXY@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6174123_40	485913.Krac_4790	1.203e-59	225.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_6174123_73	1179773.BN6_52300	6.662e-11	71.0	COG1309@1|root,COG1309@2|Bacteria,2IJB6@201174|Actinobacteria,4E3Y0@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6174123_29	316058.RPB_3208	7.312e-76	259.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VGB4@28211|Alphaproteobacteria,3JSB7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	MA20_32385	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_6174123_39	1120983.KB894576_gene3393	1.152e-59	225.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,1JMZB@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	Thioesterase-like superfamily	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
CMS3_k127_6174123_0	1254432.SCE1572_31185	0.0	1122.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42Z54@68525|delta/epsilon subdivisions,2WUB9@28221|Deltaproteobacteria,2YYC4@29|Myxococcales	28221|Deltaproteobacteria	J	Anticodon-binding domain of tRNA	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CMS3_k127_6174123_60	391625.PPSIR1_09036	2.589e-29	120.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2Z1V1@29|Myxococcales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS3_k127_6174123_67	391625.PPSIR1_09041	2.392e-21	103.0	COG0254@1|root,COG0254@2|Bacteria	2|Bacteria	J	rRNA binding	rpmE2	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS3_k127_6174123_13	1415166.NONO_c43450	2.399e-117	386.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4G0YV@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_6174123_66	1123355.JHYO01000010_gene3500	3.718e-25	108.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,36YKG@31993|Methylocystaceae	28211|Alphaproteobacteria	J	Ribosomal L28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS3_k127_6174123_28	1137799.GZ78_06900	1.227e-76	265.0	COG4221@1|root,COG4221@2|Bacteria,1MV0A@1224|Proteobacteria,1RSK5@1236|Gammaproteobacteria,1XNGS@135619|Oceanospirillales	135619|Oceanospirillales	S	KR domain	-	-	1.1.1.56	ko:K00039	ko00040,ko01100,map00040,map01100	-	R01895	RC00102	ko00000,ko00001,ko01000	-	-	-	adh_short
CMS3_k127_6174123_16	1333998.M2A_1962	4.585e-107	352.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_06735	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_6174123_63	522306.CAP2UW1_1402	3.397e-26	127.0	COG1842@1|root,COG1842@2|Bacteria,1R9B6@1224|Proteobacteria,2VNGF@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	phage shock protein A, PspA	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS3_k127_6174123_11	237368.SCABRO_03044	5.476e-129	427.0	COG2204@1|root,COG2204@2|Bacteria,2IXIQ@203682|Planctomycetes	203682|Planctomycetes	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6174123_61	646529.Desaci_0141	7.811e-29	135.0	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,24IAZ@186801|Clostridia,261YP@186807|Peptococcaceae	186801|Clostridia	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
CMS3_k127_6174123_57	443144.GM21_3168	7.167e-32	141.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43E1J@68525|delta/epsilon subdivisions,2WM21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_6174123_54	1131269.AQVV01000003_gene681	8.518e-34	132.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.13.12.21	ko:K15969	ko01057,ko01130,map01057,map01130	M00783	R06700	RC01658	ko00000,ko00001,ko00002,ko01000	-	-	-	ABM
CMS3_k127_6174123_31	748247.AZKH_3608	1.184e-73	266.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,2KYI9@206389|Rhodocyclales	206389|Rhodocyclales	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_6174123_70	596151.DesfrDRAFT_2898	1.374e-15	89.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_6174123_17	1245471.PCA10_27070	1.138e-106	377.0	COG0421@1|root,COG0421@2|Bacteria,1QU1A@1224|Proteobacteria,1T1KW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_6174123_43	1231391.AMZF01000014_gene2350	1.74e-55	199.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2WG5G@28216|Betaproteobacteria,3T93V@506|Alcaligenaceae	28216|Betaproteobacteria	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CMS3_k127_6174123_25	402881.Plav_1560	2.163e-83	289.0	COG2866@1|root,COG2866@2|Bacteria,1N6CX@1224|Proteobacteria,2U3MG@28211|Alphaproteobacteria	1224|Proteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
CMS3_k127_6174123_33	391735.Veis_1133	6.368e-70	254.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VP70@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.3,1.3.8.7	ko:K00249,ko:K07545	ko00071,ko00280,ko00410,ko00623,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01220,ko03320,map00071,map00280,map00410,map00623,map00640,map01100,map01110,map01120,map01130,map01200,map01212,map01220,map03320	M00013,M00036,M00087,M00418	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R05584	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC02037	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6174123_9	391735.Veis_1134	1.436e-133	454.0	COG1960@1|root,COG1960@2|Bacteria,1NCCF@1224|Proteobacteria,2VTAD@28216|Betaproteobacteria,4AHS9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Acyl-CoA dehydrogenase, type 2, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6174123_32	439235.Dalk_1981	3.974e-73	256.0	COG1028@1|root,COG1028@2|Bacteria,1MXNY@1224|Proteobacteria,43AI2@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K18335	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10690,R11671	RC00029,RC00089,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_6174123_10	472759.Nhal_1236	3.067e-129	450.0	COG1033@1|root,COG1033@2|Bacteria,1QW3H@1224|Proteobacteria,1RZA3@1236|Gammaproteobacteria,1X2NT@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_6174123_37	1313421.JHBV01000041_gene3598	1.376e-68	248.0	COG4638@1|root,COG4638@2|Bacteria,4NYTC@976|Bacteroidetes	976|Bacteroidetes	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_6174123_21	1265503.KB905169_gene190	1.049e-98	341.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS3_k127_6174123_41	7739.XP_002601740.1	1.398e-56	209.0	COG5285@1|root,KOG3290@2759|Eukaryota,38EX9@33154|Opisthokonta,3B9VM@33208|Metazoa,3CV1M@33213|Bilateria,488Y9@7711|Chordata	33208|Metazoa	I	phytanoyl-CoA dioxygenase activity	PHYH	GO:0001561,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006103,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006720,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0008198,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019395,GO:0019752,GO:0030258,GO:0031406,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043648,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0048037,GO:0048244,GO:0051179,GO:0051186,GO:0051213,GO:0051234,GO:0051641,GO:0051649,GO:0055114,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097089,GO:1901575	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_6174123_38	856793.MICA_690	3.402e-61	217.0	COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2U5MZ@28211|Alphaproteobacteria,4BQE2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_6174123_18	1444712.BN1013_00060	6.106e-101	346.0	COG0399@1|root,COG0399@2|Bacteria,2JFE1@204428|Chlamydiae	204428|Chlamydiae	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	1.17.1.1,2.6.1.98	ko:K12452,ko:K13017	ko00520,map00520	-	R03391,R03392,R10141	RC00006,RC00230,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_6174123_51	316058.RPB_2806	2.296e-35	154.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,2UC1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
CMS3_k127_6174123_19	1394178.AWOO02000066_gene156	4.04e-100	344.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_6174123_36	402881.Plav_0758	6.273e-69	252.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TUT7@28211|Alphaproteobacteria,1JNXV@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS3_k127_6174123_5	1089544.KB912942_gene4161	1.299e-182	599.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_6174123_23	1192034.CAP_4855	1.546e-93	322.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,438PG@68525|delta/epsilon subdivisions,2X3X6@28221|Deltaproteobacteria,2YXF3@29|Myxococcales	28221|Deltaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_6174123_2	1541065.JRFE01000014_gene1863	3.678e-224	711.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria,3VMF5@52604|Pleurocapsales	1117|Cyanobacteria	Q	Copper amine oxidase, enzyme domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
CMS3_k127_6174123_53	983917.RGE_12000	2.354e-34	141.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2WFS6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_6174123_3	1121878.AUGL01000024_gene3725	8.455e-220	762.0	COG0824@1|root,COG1520@1|root,COG2133@1|root,COG2273@1|root,COG3291@1|root,COG3507@1|root,COG3866@1|root,COG4733@1|root,COG0824@2|Bacteria,COG1520@2|Bacteria,COG2133@2|Bacteria,COG2273@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3866@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.31,3.2.1.45	ko:K01195,ko:K01201,ko:K07107,ko:K20276	ko00040,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko02024,ko04142,map00040,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map02024,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R01498,R04979,R07818,R08127,R08260,R10830	RC00055,RC00059,RC00171,RC00451,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	GH30	-	CBM_6,DUF1349,GSDH,PKD,RicinB_lectin_2,ThuA
CMS3_k127_6174123_55	502025.Hoch_5112	4.899e-33	151.0	COG5306@1|root,COG5306@2|Bacteria,1R0NH@1224|Proteobacteria,431NK@68525|delta/epsilon subdivisions,2WWPP@28221|Deltaproteobacteria	2|Bacteria	S	Domain of unknown function (DUF2341)	-	-	3.4.14.5	ko:K01278,ko:K03561	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko04090,ko04147	1.A.30.2.1	-	-	DUF1735,DUF2341,Laminin_G_3,fn3
CMS3_k127_6174123_52	926554.KI912640_gene1383	1.427e-34	139.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_4
CMS3_k127_6174123_6	264198.Reut_B4987	6.609e-161	516.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1K2TY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6174123_68	1380394.JADL01000014_gene241	6.397e-20	104.0	COG1977@1|root,COG1977@2|Bacteria,1N9QE@1224|Proteobacteria,2UKCD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	-
CMS3_k127_6174123_65	573413.Spirs_0328	6.002e-26	113.0	COG0735@1|root,COG0735@2|Bacteria,2J8AC@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the Fur family	fur	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_6174123_30	391625.PPSIR1_36702	1.42e-75	256.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2YV2V@29|Myxococcales	28221|Deltaproteobacteria	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS3_k127_6174123_22	608538.HTH_1527	5.673e-98	336.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,DUF3501,Fer4_8
CMS3_k127_6174123_48	502025.Hoch_2200	4.392e-43	164.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
CMS3_k127_6174123_42	1123072.AUDH01000002_gene2286	4.088e-56	199.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,2JSEH@204441|Rhodospirillales	204441|Rhodospirillales	O	Redoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
CMS3_k127_6174123_14	666685.R2APBS1_3815	5.817e-114	377.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RN94@1236|Gammaproteobacteria,1X8WG@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Radical_SAM
CMS3_k127_6174123_27	543632.JOJL01000004_gene4400	6.201e-81	284.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria,4DHYY@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
CMS3_k127_6174123_15	1122939.ATUD01000016_gene1882	1.134e-113	380.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4CQP7@84995|Rubrobacteria	84995|Rubrobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_6174123_44	345341.KUTG_02525	6.482e-54	197.0	COG0500@1|root,COG2226@2|Bacteria,2IDNA@201174|Actinobacteria,4E5M5@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_6174123_50	1128421.JAGA01000003_gene3091	2.48e-37	163.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_6174123_24	243231.GSU2270	9.514e-84	304.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,43T9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS3_k127_6174123_69	663610.JQKO01000008_gene186	4.069e-17	96.0	COG0727@1|root,COG0727@2|Bacteria,1RJ0V@1224|Proteobacteria,2U8AG@28211|Alphaproteobacteria,3NB68@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6174123_49	1161401.ASJA01000016_gene1347	1.936e-40	154.0	COG0537@1|root,COG0537@2|Bacteria,1N49J@1224|Proteobacteria,2UE43@28211|Alphaproteobacteria,44000@69657|Hyphomonadaceae	28211|Alphaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	HIT
CMS3_k127_6174123_46	1120956.JHZK01000019_gene2455	3.762e-46	169.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,2U9MS@28211|Alphaproteobacteria,1JP5M@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Hemimethylated DNA-binding protein YccV like	hspQ	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
CMS3_k127_6174123_75	195250.CM001776_gene1399	9.331e-07	61.0	COG5305@1|root,COG5305@2|Bacteria,1G2NQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6174123_58	1457393.AZ09_13305	4.661e-30	132.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS3_k127_6174123_64	75379.Tint_1119	5.353e-26	119.0	COG3615@1|root,COG3615@2|Bacteria,1QVHF@1224|Proteobacteria,2VX3R@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Domain of unknown function (DUF1971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1971,DUF3565
CMS3_k127_6174123_47	179408.Osc7112_1046	4.39e-45	190.0	COG5331@1|root,COG5331@2|Bacteria,1G765@1117|Cyanobacteria,1HFFY@1150|Oscillatoriales	1117|Cyanobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS3_k127_6174123_4	489825.LYNGBM3L_22030	1.082e-196	627.0	COG3961@1|root,COG3961@2|Bacteria,1G1A5@1117|Cyanobacteria,1H9TP@1150|Oscillatoriales	1117|Cyanobacteria	GH	Belongs to the TPP enzyme family	pdc	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_6174123_74	1279009.ADICEAN_00258	2.101e-07	64.0	COG1807@1|root,COG1807@2|Bacteria,4NMVP@976|Bacteroidetes,47U0B@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6174123_12	314230.DSM3645_12111	1.12e-125	441.0	COG1413@1|root,COG3303@1|root,COG1413@2|Bacteria,COG3303@2|Bacteria,2J0SN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_6174123_72	316067.Geob_1424	5.843e-11	77.0	COG1287@1|root,COG1287@2|Bacteria,1NYIS@1224|Proteobacteria,430I0@68525|delta/epsilon subdivisions,2WW3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
CMS3_k127_6202164_4	857087.Metme_3564	2.41e-44	172.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,1S32X@1236|Gammaproteobacteria,1XGBP@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
CMS3_k127_6202164_5	522306.CAP2UW1_2498	5.983e-41	173.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria	1224|Proteobacteria	I	Dehydratase	MA20_00775	-	4.2.1.148,4.2.1.56	ko:K14449,ko:K18290	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R02491,R05076	RC00730,RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
CMS3_k127_6202164_1	1380390.JIAT01000010_gene3561	1.5e-156	526.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CRQG@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2
CMS3_k127_6202164_2	1283299.AUKG01000002_gene4334	6.37e-132	426.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CSIF@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
CMS3_k127_6202164_0	1160718.SU9_32038	3.782e-171	549.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
CMS3_k127_6202164_3	926550.CLDAP_21250	4.306e-110	368.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CMS3_k127_6205144_0	161156.JQKW01000008_gene554	4.89e-21	105.0	COG4206@1|root,COG4206@2|Bacteria,2GH1H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
CMS3_k127_6215621_6	1121930.AQXG01000015_gene1848	8.787e-131	466.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS3_k127_6215621_1	984262.SGRA_4042	2.648e-169	582.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia	976|Bacteroidetes	S	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
CMS3_k127_6215621_15	1502850.FG91_00547	1.294e-28	130.0	COG2771@1|root,COG2771@2|Bacteria,1MWC0@1224|Proteobacteria,2U1YZ@28211|Alphaproteobacteria,2KC9H@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6215621_14	448385.sce1096	3.439e-46	188.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_6215621_0	1380394.JADL01000002_gene1789	1.613e-262	833.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TQSC@28211|Alphaproteobacteria,2JREM@204441|Rhodospirillales	204441|Rhodospirillales	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_6215621_3	402881.Plav_0806	4.36e-152	495.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,2V8ID@28211|Alphaproteobacteria,1JQJ9@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
CMS3_k127_6215621_5	565045.NOR51B_2828	1.474e-132	453.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	amidohydrolase	hipO	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_6215621_8	391612.CY0110_29729	1.001e-84	294.0	COG1763@1|root,COG1763@2|Bacteria,1G6XG@1117|Cyanobacteria	1117|Cyanobacteria	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6215621_12	1288494.EBAPG3_24610	2.971e-54	205.0	COG1073@1|root,COG1073@2|Bacteria,1QUQB@1224|Proteobacteria,2W8W8@28216|Betaproteobacteria,373YM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6215621_10	631362.Thi970DRAFT_03892	2.268e-63	243.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,1S2UH@1236|Gammaproteobacteria,1WYPZ@135613|Chromatiales	135613|Chromatiales	P	PFAM Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS3_k127_6215621_11	221288.JH992901_gene529	6.244e-63	236.0	COG1132@1|root,COG1132@2|Bacteria,1GBJ5@1117|Cyanobacteria,1JJXF@1189|Stigonemataceae	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS3_k127_6215621_9	671143.DAMO_2164	1.053e-63	246.0	COG0120@1|root,COG0120@2|Bacteria,2NPMQ@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.7.1.12,2.7.1.15,5.3.1.6	ko:K00851,ko:K00852,ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01051,R01056,R01737,R02750	RC00002,RC00017,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS3_k127_6215621_2	671143.DAMO_0488	7.301e-167	545.0	COG0166@1|root,COG0166@2|Bacteria,2NP2H@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
CMS3_k127_6215621_21	246197.MXAN_3504	2.192e-16	95.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2Z1RM@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6215621_19	1297742.A176_01322	7.296e-17	97.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2Z1RM@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6215621_16	404589.Anae109_0394	5.634e-28	123.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,42YY2@68525|delta/epsilon subdivisions,2WUI6@28221|Deltaproteobacteria,2Z0E8@29|Myxococcales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_6215621_20	290397.Adeh_4033	1.348e-16	86.0	COG0848@1|root,COG0848@2|Bacteria,1Q5DA@1224|Proteobacteria,42VMC@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_6215621_18	13035.Dacsa_1642	1.111e-19	105.0	COG3225@1|root,COG3225@2|Bacteria,1G0JN@1117|Cyanobacteria	1117|Cyanobacteria	N	transport system involved in gliding motility, auxiliary component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS3_k127_6215621_17	706587.Desti_2982	1.491e-22	113.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
CMS3_k127_6215621_13	1122603.ATVI01000006_gene675	7.489e-49	189.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1XCE4@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6215621_7	344747.PM8797T_22153	2.218e-113	392.0	COG0128@1|root,COG0128@2|Bacteria,2IXRF@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS3_k127_6215621_4	667014.Thein_0855	6.013e-139	455.0	COG0111@1|root,COG2150@1|root,COG0111@2|Bacteria,COG2150@2|Bacteria,2GH7H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_625501_2	1440774.Y900_025615	2.647e-51	186.0	2F5RB@1|root,330DX@2|Bacteria,2IK0D@201174|Actinobacteria,239AV@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_625501_3	1121918.ARWE01000001_gene3653	3.253e-16	81.0	COG5460@1|root,COG5460@2|Bacteria,1NQ45@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
CMS3_k127_625501_1	298654.FraEuI1c_4204	2.351e-97	329.0	COG1024@1|root,COG1024@2|Bacteria,2HEIS@201174|Actinobacteria,4ESHH@85013|Frankiales	201174|Actinobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_625501_0	1168065.DOK_08889	3.944e-218	708.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J5AG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS3_k127_6309372_1	1242864.D187_002372	2.614e-92	340.0	COG4143@1|root,COG4143@2|Bacteria,1R4IE@1224|Proteobacteria,42QHK@68525|delta/epsilon subdivisions,2WUK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6309372_0	224911.27352915	1.046e-241	766.0	COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,3JUQU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
CMS3_k127_6309372_2	1150474.JQJI01000007_gene232	6.514e-24	116.0	COG0071@1|root,COG0071@2|Bacteria,2GDCG@200918|Thermotogae	200918|Thermotogae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_6309372_3	710687.KI912270_gene100	6.844e-13	68.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,234NV@1762|Mycobacteriaceae	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_63724_3	402881.Plav_2677	2.12e-104	348.0	COG5285@1|root,COG5285@2|Bacteria,1QRDD@1224|Proteobacteria,2U0EC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_63724_19	1090319.KE386571_gene1880	0.000192	52.0	2B90Y@1|root,322BP@2|Bacteria,1N5XI@1224|Proteobacteria,2UKC5@28211|Alphaproteobacteria,2K27M@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_63724_6	439235.Dalk_2437	9.871e-91	317.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,42NVQ@68525|delta/epsilon subdivisions,2WJFT@28221|Deltaproteobacteria,2MHX5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS3_k127_63724_4	402881.Plav_0555	7.475e-97	346.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria,1JNZY@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_63724_9	502025.Hoch_2284	2.887e-43	178.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,43AH9@68525|delta/epsilon subdivisions,2X5XB@28221|Deltaproteobacteria,2Z37F@29|Myxococcales	28221|Deltaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_63724_11	671143.DAMO_0294	1.484e-27	130.0	COG0500@1|root,COG0535@1|root,COG0535@2|Bacteria,COG2226@2|Bacteria,2NPMF@2323|unclassified Bacteria	2|Bacteria	Q	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Methyltransf_11,Methyltransf_25,Radical_SAM,SPASM
CMS3_k127_63724_8	243233.MCA1593	8.492e-48	196.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,1S9I3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nuclease	Z012_04225	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
CMS3_k127_63724_10	329726.AM1_3288	1.519e-34	137.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	fosB	GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896	2.5.1.18	ko:K11210,ko:K21253,ko:K21264,ko:K21265	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Glyoxalase
CMS3_k127_63724_0	469383.Cwoe_4211	4.754e-289	904.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CMS3_k127_63724_7	794903.OPIT5_11735	9.129e-49	184.0	COG0500@1|root,COG0500@2|Bacteria,46V7N@74201|Verrucomicrobia,3K8BC@414999|Opitutae	414999|Opitutae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_63724_18	1163409.UUA_11793	5.129e-07	64.0	2DBT3@1|root,2ZAV9@2|Bacteria,1R6IW@1224|Proteobacteria,1SM7Y@1236|Gammaproteobacteria,1X9EF@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_63724_12	1121272.KB903291_gene3569	5.55e-27	130.0	COG2320@1|root,COG2320@2|Bacteria,2HG2M@201174|Actinobacteria,4DJWR@85008|Micromonosporales	201174|Actinobacteria	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
CMS3_k127_63724_15	1122137.AQXF01000001_gene2693	2.236e-22	102.0	2EGX5@1|root,33APA@2|Bacteria,1NHMF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS3_k127_63724_5	1123320.KB889689_gene538	4.922e-94	319.0	COG2030@1|root,COG2030@2|Bacteria,2GJJI@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
CMS3_k127_63724_17	762376.AXYL_02494	5.561e-11	75.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VPR2@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_63724_13	330779.Saci_1106	9.034e-27	129.0	arCOG07204@1|root,arCOG07204@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_63724_1	247633.GP2143_12911	3.012e-190	607.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,1RY0V@1236|Gammaproteobacteria,1J7G3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_63724_2	247634.GPB2148_2468	2.192e-150	499.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,1J81X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS3_k127_63724_16	96561.Dole_1235	7.969e-15	82.0	COG0811@1|root,COG0811@2|Bacteria,1NFJP@1224|Proteobacteria,42VKH@68525|delta/epsilon subdivisions,2WRE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
CMS3_k127_63724_14	1232410.KI421428_gene1125	6.354e-25	123.0	2C347@1|root,32S30@2|Bacteria,1N5T7@1224|Proteobacteria,42TIS@68525|delta/epsilon subdivisions,2WQH1@28221|Deltaproteobacteria,43TM7@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6408930_12	1484460.JSWG01000015_gene1186	5.123e-16	80.0	COG0591@1|root,COG0591@2|Bacteria,4PKS6@976|Bacteroidetes,1IJEC@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
CMS3_k127_6408930_9	398578.Daci_4515	3.73e-32	145.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
CMS3_k127_6408930_11	1001530.BACE01000011_gene2404	1.671e-21	111.0	COG1404@1|root,COG2304@1|root,COG3211@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3211@2|Bacteria,1PDY9@1224|Proteobacteria,1SPHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_6408930_7	1049564.TevJSym_aq00670	2.145e-68	251.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS3_k127_6408930_6	1049564.TevJSym_aq00680	7.302e-69	252.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfE2	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS3_k127_6408930_10	1049564.TevJSym_aq00690	1.416e-31	142.0	COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
CMS3_k127_6408930_4	580332.Slit_2484	2.069e-90	326.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VKUY@28216|Betaproteobacteria,44WPH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS3_k127_6408930_2	1049564.TevJSym_br00030	7.892e-127	421.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB
CMS3_k127_6408930_15	2340.JV46_16940	7.261e-06	61.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.2.7.1	ko:K03737,ko:K05337	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_6408930_0	1379270.AUXF01000001_gene2161	0.0	1338.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_6408930_5	1049564.TevJSym_bb00010	1.256e-86	302.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
CMS3_k127_6408930_3	1049564.TevJSym_bb00040	1.22e-97	344.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_6408930_1	1049564.TevJSym_bb00050	6.208e-217	705.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_6408930_16	290397.Adeh_2998	0.0003179	54.0	COG2224@1|root,COG2225@1|root,COG2224@2|Bacteria,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,42P3R@68525|delta/epsilon subdivisions,2X349@28221|Deltaproteobacteria,2YU6W@29|Myxococcales	28221|Deltaproteobacteria	H	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Hemerythrin,ICL,Malate_synthase
CMS3_k127_6408930_13	222534.KB893713_gene2333	8.488e-12	76.0	COG5470@1|root,COG5470@2|Bacteria,2IM3I@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS3_k127_6408930_14	1267533.KB906736_gene910	1.436e-08	68.0	COG4762@1|root,COG4762@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1990
CMS3_k127_6408930_8	1122137.AQXF01000002_gene580	1.721e-62	224.0	28MWZ@1|root,2ZB46@2|Bacteria,1R7K6@1224|Proteobacteria,2U4ZP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6416445_0	1313172.YM304_15410	1.36e-152	494.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_6416445_3	1348114.OM33_08070	1.872e-61	220.0	COG0652@1|root,COG0652@2|Bacteria,1RBX1@1224|Proteobacteria,1SYJW@1236|Gammaproteobacteria,2Q28R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_6416445_1	1121035.AUCH01000012_gene3047	1.391e-93	317.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,2VKZ8@28216|Betaproteobacteria,2KU6J@206389|Rhodocyclales	206389|Rhodocyclales	L	PFAM Uracil-DNA glycosylase superfamily	smuG	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
CMS3_k127_6416445_2	1278073.MYSTI_04829	7.869e-87	302.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria	1224|Proteobacteria	K	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_6438970_0	1121396.KB892946_gene2897	3.852e-21	109.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MHZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_6438970_1	1463936.JOJI01000018_gene7737	3.836e-12	74.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_6448591_7	2074.JNYD01000012_gene207	4.571e-158	511.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4DZJ7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
CMS3_k127_6448591_4	1121904.ARBP01000027_gene729	7.226e-189	608.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,47K4T@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS3_k127_6448591_22	1397527.Q670_06235	4.13e-58	212.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS3_k127_6448591_17	1123393.KB891316_gene1826	7.556e-81	289.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2VHM0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phenazine biosynthesis protein phzf family	phzF_1	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS3_k127_6448591_30	1173023.KE650771_gene4052	1.026e-24	119.0	COG3265@1|root,COG3265@2|Bacteria	2|Bacteria	G	gluconokinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS3_k127_6448591_3	670292.JH26_21755	3.186e-200	648.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,1JS3J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0061 (SELO) family	MA20_28420	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
CMS3_k127_6448591_26	269482.Bcep1808_1767	1.494e-48	188.0	COG1028@1|root,COG1028@2|Bacteria,1NYXI@1224|Proteobacteria,2WEAV@28216|Betaproteobacteria,1KHP8@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.304,1.1.1.76	ko:K03366	ko00650,map00650	-	R02855,R02946,R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short
CMS3_k127_6448591_8	1211815.CBYP010000016_gene2611	3.607e-139	458.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_6448591_18	469383.Cwoe_1636	2.177e-80	293.0	COG0454@1|root,COG0456@2|Bacteria,2GNAV@201174|Actinobacteria,4CQ54@84995|Rubrobacteria	84995|Rubrobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6448591_9	1121937.AUHJ01000005_gene2226	6.128e-122	399.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,1SWMP@1236|Gammaproteobacteria,46975@72275|Alteromonadaceae	1224|Proteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_6448591_37	1279017.AQYJ01000026_gene73	1.345e-05	52.0	2DXTJ@1|root,346GW@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6448591_27	1279017.AQYJ01000026_gene73	6.592e-41	173.0	2DXTJ@1|root,346GW@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6448591_34	1279017.AQYJ01000026_gene73	2.741e-13	76.0	2DXTJ@1|root,346GW@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6448591_23	1279017.AQYJ01000026_gene73	1.196e-56	208.0	2DXTJ@1|root,346GW@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6448591_10	1123072.AUDH01000048_gene1774	1.538e-118	394.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2U0ZZ@28211|Alphaproteobacteria,2JW7U@204441|Rhodospirillales	204441|Rhodospirillales	H	Enoyl-CoA hydratase/isomerase	menB	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_6448591_5	886293.Sinac_3574	2.521e-180	593.0	COG1902@1|root,COG1902@2|Bacteria,2IXBM@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS3_k127_6448591_11	926550.CLDAP_16050	1.741e-112	378.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS3_k127_6448591_21	247156.NFA_28030	2.537e-61	241.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,4FYH9@85025|Nocardiaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_6448591_12	1313172.YM304_34480	1.79e-106	367.0	COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria	2|Bacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CMS3_k127_6448591_20	1370121.AUWS01000023_gene2322	7.402e-64	230.0	COG3871@1|root,COG3871@2|Bacteria,2IFC3@201174|Actinobacteria,238T2@1762|Mycobacteriaceae	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_6448591_13	1151118.KB895793_gene1649	1.613e-96	329.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	frc	-	2.8.3.15,2.8.3.16	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS3_k127_6448591_35	234267.Acid_2363	1.126e-12	72.0	COG1309@1|root,COG1309@2|Bacteria,3Y8G6@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_6448591_33	1121957.ATVL01000010_gene332	1.544e-15	92.0	COG0477@1|root,COG0477@2|Bacteria,4PKB1@976|Bacteroidetes,47JJE@768503|Cytophagia	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
CMS3_k127_6448591_14	1379270.AUXF01000002_gene1851	5.162e-96	331.0	COG0477@1|root,COG0477@2|Bacteria,1ZT3N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sugar (and other) transporter	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
CMS3_k127_6448591_15	1380390.JIAT01000010_gene4575	4.737e-91	322.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_6448591_25	215803.DB30_1626	9.301e-50	189.0	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,43811@68525|delta/epsilon subdivisions,2X3B3@28221|Deltaproteobacteria,2YV70@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
CMS3_k127_6448591_28	1254432.SCE1572_50650	2.494e-35	151.0	COG1846@1|root,COG1846@2|Bacteria,1NJH3@1224|Proteobacteria,4350E@68525|delta/epsilon subdivisions,2WZBA@28221|Deltaproteobacteria,2Z1RN@29|Myxococcales	28221|Deltaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_6448591_19	1038859.AXAU01000011_gene2582	1.36e-77	276.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2TS7X@28211|Alphaproteobacteria,3JXY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K22369	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_6448591_31	710685.MycrhN_4787	3.888e-23	108.0	COG1309@1|root,COG1309@2|Bacteria,2GKU3@201174|Actinobacteria,2357T@1762|Mycobacteriaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_C_6,TetR_N
CMS3_k127_6448591_29	518766.Rmar_0880	1.799e-29	136.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1FJ10@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS3_k127_6448591_2	391625.PPSIR1_40260	1.92e-234	763.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_6448591_0	1278073.MYSTI_07874	1.456e-297	953.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria,439FZ@68525|delta/epsilon subdivisions,2X4RS@28221|Deltaproteobacteria,2YZGC@29|Myxococcales	28221|Deltaproteobacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6448591_36	715451.ambt_18990	5.954e-07	64.0	COG1361@1|root,COG5276@1|root,COG1361@2|Bacteria,COG5276@2|Bacteria,1R1M7@1224|Proteobacteria,1T559@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6448591_32	1122970.AUHC01000011_gene2699	9.056e-17	87.0	COG3631@1|root,COG3631@2|Bacteria,1RH7J@1224|Proteobacteria,2UB56@28211|Alphaproteobacteria,2K5TZ@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_6448591_16	1123274.KB899415_gene2442	6.158e-84	301.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,2J9V6@203691|Spirochaetes	203691|Spirochaetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,HATPase_c,HisKA,PAS,PAS_9,Response_reg
CMS3_k127_6448591_24	1183438.GKIL_3171	1.713e-51	207.0	2DB9X@1|root,2Z7ZS@2|Bacteria,1G3ZT@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3445)	-	-	1.14.13.238	ko:K22342	-	-	-	-	ko00000,ko01000	-	-	-	DUF3445
CMS3_k127_6448591_1	765869.BDW_06135	3.259e-280	879.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2MTGA@213481|Bdellovibrionales,2WJ0R@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS3_k127_6448591_6	1168065.DOK_06979	9.157e-171	543.0	COG5361@1|root,COG5361@2|Bacteria,1R4D9@1224|Proteobacteria,1S116@1236|Gammaproteobacteria,1J905@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_644994_5	391625.PPSIR1_16640	1.803e-39	161.0	COG3714@1|root,COG3714@2|Bacteria,1PCNW@1224|Proteobacteria,435D5@68525|delta/epsilon subdivisions,2WZQQ@28221|Deltaproteobacteria,2Z2IZ@29|Myxococcales	28221|Deltaproteobacteria	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
CMS3_k127_644994_2	1048339.KB913029_gene2967	5.749e-112	378.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4EVXM@85013|Frankiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS3_k127_644994_8	1125971.ASJB01000080_gene7465	1.231e-14	82.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4E225@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_644994_6	298653.Franean1_3790	1.888e-29	120.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4EW5T@85013|Frankiales	201174|Actinobacteria	K	transcriptional regulator, ArsR family	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS3_k127_644994_3	269482.Bcep1808_3292	1.349e-79	274.0	COG1752@1|root,COG1752@2|Bacteria,1REEJ@1224|Proteobacteria,2VRMU@28216|Betaproteobacteria,1K0ZP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS3_k127_644994_0	1333998.M2A_1395	2.381e-196	627.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2U3CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_644994_7	1121472.AQWN01000003_gene1525	5.773e-24	109.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,26230@186807|Peptococcaceae	186801|Clostridia	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_644994_4	96561.Dole_0796	3.984e-57	226.0	COG2982@1|root,COG2982@2|Bacteria,1P6EN@1224|Proteobacteria,42TSC@68525|delta/epsilon subdivisions,2WQ20@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_644994_1	485913.Krac_11674	5.55e-122	399.0	COG2141@1|root,COG2141@2|Bacteria,2G878@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_6464738_5	330214.NIDE3764	1.835e-81	282.0	28PNA@1|root,2ZCB3@2|Bacteria	2|Bacteria	S	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS3_k127_6464738_1	335543.Sfum_2352	7.805e-148	493.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MQI5@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS3_k127_6464738_0	710685.MycrhN_2374	1.023e-171	554.0	COG1233@1|root,COG1233@2|Bacteria,2IE6C@201174|Actinobacteria,235D5@1762|Mycobacteriaceae	201174|Actinobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_6464738_8	931627.MycrhDRAFT_6729	1.292e-45	172.0	COG1309@1|root,COG1309@2|Bacteria,2HMJ1@201174|Actinobacteria,232DB@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6464738_6	1158146.KB907122_gene146	9.472e-49	184.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S82H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
CMS3_k127_6464738_2	1282876.BAOK01000001_gene3466	5.494e-131	431.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,2U5M0@28211|Alphaproteobacteria,4BT1G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_6464738_7	1047013.AQSP01000106_gene1773	1.625e-46	192.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS3_k127_6464738_3	326424.FRAAL3123	3.288e-101	343.0	COG2141@1|root,COG2141@2|Bacteria,2IB78@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_6464738_4	518766.Rmar_1973	6.58e-92	310.0	COG1878@1|root,COG1878@2|Bacteria,4PIWM@976|Bacteroidetes,1FJPB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative cyclase	-	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
CMS3_k127_6472027_4	882.DVU_3216	6.29e-14	85.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria,2M8XD@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA,dCache_1,dCache_2
CMS3_k127_6472027_3	1268068.PG5_29880	4.736e-25	117.0	COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS3_k127_6472027_2	1192034.CAP_1192	5.238e-36	153.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2YVHM@29|Myxococcales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CMS3_k127_6472027_1	861299.J421_2457	7.614e-52	209.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
CMS3_k127_6472027_0	1089547.KB913013_gene2821	8.244e-102	341.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KX2@768503|Cytophagia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_6472027_5	439235.Dalk_0972	0.0008296	49.0	COG5414@1|root,COG5414@2|Bacteria,1NYZX@1224|Proteobacteria,430TY@68525|delta/epsilon subdivisions,2WVMW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	histone acetyltransferase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6473043_7	426117.M446_2713	2.785e-76	265.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TR5N@28211|Alphaproteobacteria,1JRFY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_6473043_9	1123242.JH636435_gene2917	6.174e-52	202.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_6473043_2	1380391.JIAS01000013_gene3713	1.658e-234	739.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,2JPC4@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_6473043_3	868595.Desca_1069	4.491e-147	500.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS3_k127_6473043_0	1125863.JAFN01000001_gene353	0.0	1444.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS3_k127_6473043_4	1125863.JAFN01000001_gene352	5.32e-134	458.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS3_k127_6473043_5	1121430.JMLG01000006_gene1763	3.301e-131	447.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS3_k127_6473043_6	1232410.KI421413_gene593	3.931e-108	372.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_6473043_10	401526.TcarDRAFT_2094	1.638e-47	180.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4H3ZG@909932|Negativicutes	909932|Negativicutes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS3_k127_6473043_11	42565.FP66_08005	2.47e-46	181.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XJ0T@135619|Oceanospirillales	135619|Oceanospirillales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS3_k127_6473043_1	323848.Nmul_A1751	1.433e-245	788.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,372EW@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS3_k127_6473043_8	351607.Acel_0416	8.353e-59	216.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4ERZQ@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS3_k127_6473043_12	396588.Tgr7_1257	1.414e-10	68.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1WZEE@135613|Chromatiales	135613|Chromatiales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
CMS3_k127_6477205_10	1121116.KB894770_gene1192	9.779e-27	122.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,4AAZJ@80864|Comamonadaceae	28216|Betaproteobacteria	KL	Helicase c2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
CMS3_k127_6477205_3	439235.Dalk_1753	1.456e-103	346.0	COG0300@1|root,COG0623@1|root,COG0300@2|Bacteria,COG0623@2|Bacteria,1R090@1224|Proteobacteria,43CRU@68525|delta/epsilon subdivisions,2X7ZF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_6477205_2	391625.PPSIR1_07757	1.243e-122	416.0	COG0332@1|root,COG0332@2|Bacteria,1RB9M@1224|Proteobacteria,42YNV@68525|delta/epsilon subdivisions,2WTQM@28221|Deltaproteobacteria,2YYYC@29|Myxococcales	28221|Deltaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_6477205_5	56780.SYN_01697	2.313e-73	252.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria	1224|Proteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090	FabA
CMS3_k127_6477205_4	56780.SYN_01696	2.421e-89	310.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2MQF5@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_6477205_8	56780.SYN_01695	4.296e-38	147.0	COG0764@1|root,COG0764@2|Bacteria,1N0HJ@1224|Proteobacteria,42ZU6@68525|delta/epsilon subdivisions,2WV96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS3_k127_6477205_1	56780.SYN_01694	6.091e-172	556.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MQ97@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_6477205_11	439235.Dalk_1749	3.509e-18	87.0	COG0236@1|root,COG0236@2|Bacteria,1NII3@1224|Proteobacteria,433M2@68525|delta/epsilon subdivisions,2WXKX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_6477205_6	56780.SYN_01692	1.168e-54	200.0	COG0204@1|root,COG0204@2|Bacteria,1P3XM@1224|Proteobacteria	1224|Proteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_6477205_15	1111730.ATTM01000002_gene1019	8.826e-05	53.0	COG0736@1|root,COG0736@2|Bacteria,4NVXB@976|Bacteroidetes,1I517@117743|Flavobacteriia,2NW9I@237|Flavobacterium	976|Bacteroidetes	I	Belongs to the P-Pant transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
CMS3_k127_6477205_0	502025.Hoch_2100	0.0	1240.0	COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,1P6RE@1224|Proteobacteria,43A2M@68525|delta/epsilon subdivisions,2X1XW@28221|Deltaproteobacteria,2YX2T@29|Myxococcales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase, central region	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
CMS3_k127_6477205_12	888060.HMPREF9081_1997	1.021e-14	87.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4H54R@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS3_k127_6477205_7	926566.Terro_2744	1.84e-40	167.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_6477205_14	1040989.AWZU01000018_gene2742	3.018e-05	54.0	COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,3JT0T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial SH3 domain	MA20_24010	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	SH3_4
CMS3_k127_6477205_9	1499967.BAYZ01000125_gene2598	3.651e-33	148.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
CMS3_k127_6477205_13	458817.Shal_1957	7.976e-06	48.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1S49X@1236|Gammaproteobacteria,2Q9ZY@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
CMS3_k127_6486520_17	1125863.JAFN01000001_gene535	9.852e-29	131.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_6486520_10	671143.DAMO_0194	2.529e-85	308.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
CMS3_k127_6486520_9	880072.Desac_1327	2.527e-99	342.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2MRYR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Undecaprenyl-phosphate galactose phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_6486520_7	670487.Ocepr_1994	7.084e-119	411.0	COG0686@1|root,COG0686@2|Bacteria,1WIQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_6486520_1	344747.PM8797T_26375	1.816e-148	484.0	COG2046@1|root,COG2046@2|Bacteria,2J517@203682|Planctomycetes	203682|Planctomycetes	H	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
CMS3_k127_6486520_24	502025.Hoch_1577	0.0002695	53.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6486520_23	671143.DAMO_1029	4.003e-13	79.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	2.7.7.80,2.8.1.11,3.13.1.6	ko:K21140,ko:K21147	ko04122,map04122	-	R07459,R07461,R11524	RC00043,RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,Rhodanese,ThiF
CMS3_k127_6486520_20	448385.sce5758	6.871e-18	97.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,42VZX@68525|delta/epsilon subdivisions,2WYIT@28221|Deltaproteobacteria,2YW0H@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_6486520_3	1232436.CAPF01000014_gene742	1.216e-141	475.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CU9B@84998|Coriobacteriia	84998|Coriobacteriia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_6486520_0	1125863.JAFN01000001_gene2957	3.616e-228	731.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_6486520_11	1210884.HG799469_gene14022	1.545e-84	317.0	COG0438@1|root,COG0438@2|Bacteria,2IXRB@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_6486520_8	575540.Isop_1639	3.951e-106	361.0	COG0399@1|root,COG0399@2|Bacteria,2IXRE@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_6486520_5	671143.DAMO_0264	9.67e-122	409.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_6486520_2	706587.Desti_4172	2.353e-145	472.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria,2MQYT@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
CMS3_k127_6486520_16	768710.DesyoDRAFT_2212	1.094e-43	173.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,2601Y@186807|Peptococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS3_k127_6486520_12	1183438.GKIL_2080	1.135e-77	295.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS3_k127_6486520_19	204669.Acid345_4518	9.805e-21	97.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia	204432|Acidobacteriia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_6486520_6	696369.KI912183_gene2353	9.209e-121	401.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS3_k127_6486520_14	1297742.A176_07038	2.797e-68	250.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS3_k127_6486520_21	1121405.dsmv_0308	7.023e-17	93.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2MKYR@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS3_k127_6486520_13	439235.Dalk_0528	1.079e-73	271.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2MNNY@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
CMS3_k127_6486520_22	570268.ANBB01000037_gene2719	1.164e-15	90.0	COG2761@1|root,COG2761@2|Bacteria,2GNBC@201174|Actinobacteria,4EKC1@85012|Streptosporangiales	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	frnE	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_6486520_18	1120971.AUCA01000002_gene1493	4.522e-27	128.0	COG1853@1|root,COG1853@2|Bacteria,1V5M1@1239|Firmicutes,4HJWQ@91061|Bacilli	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
CMS3_k127_6486520_4	1304275.C41B8_12424	2.289e-131	428.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the class I fructose-bisphosphate aldolase family	alf1	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
CMS3_k127_6486520_15	1121878.AUGL01000014_gene1627	1.146e-46	193.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	VVA1274	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_6520407_1	1121013.P873_01565	5.783e-69	261.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,1X45I@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_6520407_5	1120950.KB892708_gene4490	1.841e-44	183.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria,4DSEK@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
CMS3_k127_6520407_6	35754.JNYJ01000063_gene1423	4.367e-41	165.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria,4DEGR@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_6520407_14	1040989.AWZU01000033_gene3557	0.0006618	52.0	COG2091@1|root,COG2091@2|Bacteria,1NPFV@1224|Proteobacteria,2U4XS@28211|Alphaproteobacteria,3JWCG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6520407_9	1120950.KB892708_gene4490	1.412e-28	134.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria,4DSEK@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
CMS3_k127_6520407_13	1192034.CAP_6577	5.035e-09	69.0	COG2133@1|root,COG4935@1|root,COG2133@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Amidase_2,DUF11,Glyco_hydro_11,He_PIG,Malectin,PA14,P_proprotein
CMS3_k127_6520407_12	482537.XP_008561699.1	2.612e-24	119.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTYV@33213|Bilateria,47YVC@7711|Chordata,497BX@7742|Vertebrata,3JCD1@40674|Mammalia,35A0A@314146|Euarchontoglires	33208|Metazoa	T	positive regulation of presynaptic membrane organization	LRP4	GO:0000902,GO:0000904,GO:0001655,GO:0001822,GO:0001932,GO:0001934,GO:0001941,GO:0001942,GO:0003002,GO:0003674,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007389,GO:0007399,GO:0007416,GO:0007528,GO:0008104,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009893,GO:0009950,GO:0009953,GO:0009954,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010648,GO:0010721,GO:0010769,GO:0010771,GO:0010975,GO:0010977,GO:0014069,GO:0016020,GO:0016043,GO:0016055,GO:0016358,GO:0017147,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022404,GO:0022405,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030278,GO:0030279,GO:0030326,GO:0030424,GO:0030425,GO:0030971,GO:0031175,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031399,GO:0031401,GO:0031594,GO:0032268,GO:0032270,GO:0032279,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034185,GO:0034613,GO:0035107,GO:0035108,GO:0035113,GO:0036477,GO:0038023,GO:0040007,GO:0042303,GO:0042325,GO:0042327,GO:0042475,GO:0042476,GO:0042633,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042995,GO:0043005,GO:0043025,GO:0043113,GO:0043226,GO:0043235,GO:0043588,GO:0043679,GO:0043933,GO:0044085,GO:0044091,GO:0044297,GO:0044306,GO:0044332,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045937,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048736,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050770,GO:0050771,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051093,GO:0051124,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051641,GO:0051668,GO:0051716,GO:0051960,GO:0051961,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060828,GO:0061024,GO:0065003,GO:0065007,GO:0065008,GO:0070727,GO:0071340,GO:0071709,GO:0071840,GO:0071944,GO:0072001,GO:0072657,GO:0080090,GO:0090090,GO:0097060,GO:0097090,GO:0097104,GO:0097105,GO:0097110,GO:0097447,GO:0097458,GO:0098590,GO:0098773,GO:0098793,GO:0098794,GO:0098984,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099175,GO:0099572,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:0198738,GO:1901626,GO:1901628,GO:1901629,GO:1901631,GO:1903827,GO:1903829,GO:1903909,GO:1903911,GO:1904393,GO:1904395,GO:1904396,GO:1904398,GO:1905114,GO:1905475,GO:1905477,GO:1990709,GO:1990782,GO:2000026	-	ko:K20051	-	-	-	-	ko00000,ko04131	-	-	-	EGF_CA,FXa_inhibition,Ldl_recept_a,Ldl_recept_b,cEGF
CMS3_k127_6520407_3	246969.TAM4_1932	1.124e-59	217.0	COG1708@1|root,arCOG01204@2157|Archaea,2Y2IW@28890|Euryarchaeota,243RB@183968|Thermococci	183968|Thermococci	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS3_k127_6520407_2	1254432.SCE1572_22150	2.138e-66	256.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria,433IU@68525|delta/epsilon subdivisions,2WXIH@28221|Deltaproteobacteria,2YUYB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6520407_0	1125863.JAFN01000001_gene910	1.257e-238	748.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
CMS3_k127_6520407_7	338963.Pcar_1899	3.958e-37	146.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,43SIQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS3_k127_6520407_4	595536.ADVE02000001_gene824	1.066e-49	181.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,36XZ5@31993|Methylocystaceae	28211|Alphaproteobacteria	J	Ribosomal protein L13	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS3_k127_6520407_11	1961.JOAK01000019_gene6862	2.006e-24	113.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
CMS3_k127_6520407_8	443143.GM18_0157	8.207e-31	139.0	COG1413@1|root,COG2804@1|root,COG1413@2|Bacteria,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	2.4.1.227,2.7.11.1,3.4.11.2	ko:K01256,ko:K02563,ko:K02652,ko:K08776,ko:K12132	ko00480,ko00550,ko01100,ko01502,ko04112,map00480,map00550,map01100,map01502,map04112	-	R00899,R04951,R05032,R05662	RC00005,RC00049,RC00096,RC00141	ko00000,ko00001,ko01000,ko01001,ko01002,ko01011,ko02035,ko02044	3.A.15.2	GT28	-	HEAT_2,Sulfatase,T2SSE_N
CMS3_k127_6520407_10	485913.Krac_3240	9.103e-28	117.0	COG4427@1|root,COG4427@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
CMS3_k127_65271_40	1173025.GEI7407_3443	4.531e-11	74.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Flg_new,Glyco_hydro_88,Lipase_GDSL_2,Peptidase_C1,Prophage_tail
CMS3_k127_65271_29	426117.M446_4386	1.258e-61	229.0	COG2271@1|root,COG2271@2|Bacteria,1QV8S@1224|Proteobacteria,2TY4E@28211|Alphaproteobacteria,1JSB2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS3_k127_65271_11	1136417.AZWE01000005_gene4558	7.194e-124	406.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4DBZZ@85008|Micromonosporales	201174|Actinobacteria	I	Coenzyme A transferase	cotA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS3_k127_65271_18	1449353.JQMQ01000005_gene1221	6.19e-91	321.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,2NGHS@228398|Streptacidiphilus	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
CMS3_k127_65271_14	1121937.AUHJ01000006_gene2499	4.124e-115	398.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RPZN@1236|Gammaproteobacteria,469T4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS3_k127_65271_21	1137799.GZ78_07080	4.1e-88	299.0	COG1024@1|root,COG1024@2|Bacteria,1PSRK@1224|Proteobacteria,1RZ2F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_65271_4	1123257.AUFV01000015_gene3572	4.319e-182	576.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria,1X4JX@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_65271_17	1301098.PKB_4259	5.829e-97	328.0	COG1960@1|root,COG1960@2|Bacteria,1P4V3@1224|Proteobacteria,1RZBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_65271_30	247634.GPB2148_3250	3.396e-48	199.0	COG1545@1|root,COG1545@2|Bacteria,1RIV9@1224|Proteobacteria,1S7WJ@1236|Gammaproteobacteria,1J60Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_65271_3	1229780.BN381_350073	7.42e-192	605.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,3UXHJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
CMS3_k127_65271_2	58123.JOFJ01000013_gene4908	7.08e-192	605.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4EH5G@85012|Streptosporangiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA6	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_65271_12	471852.Tcur_3473	5.68e-123	420.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4EI03@85012|Streptosporangiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_65271_13	1207075.PputUW4_01650	4.297e-116	385.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,1RYCC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_65271_19	1229780.BN381_350076	8.068e-91	332.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,3UX9N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_65271_26	1168065.DOK_06532	3.482e-66	245.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S0DD@1236|Gammaproteobacteria,1J5PB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl dehydratase	nodN	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_65271_28	316067.Geob_1547	1.753e-62	240.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,42RRH@68525|delta/epsilon subdivisions,2WNID@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0882	Polysacc_deac_1
CMS3_k127_65271_10	880072.Desac_2832	1.243e-137	462.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42QC6@68525|delta/epsilon subdivisions,2WIRV@28221|Deltaproteobacteria,2MR30@213462|Syntrophobacterales	28221|Deltaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	arnA	-	1.1.1.305,2.1.2.13	ko:K10011,ko:K12449	ko00520,ko01100,ko01503,map00520,map01100,map01503	M00721,M00761	R01384,R01386,R07658,R07660	RC00026,RC00508,RC01575,RC01811,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,Formyl_trans_C,Formyl_trans_N
CMS3_k127_65271_23	573.JG24_24150	2.014e-78	274.0	COG0223@1|root,COG0451@1|root,COG0223@2|Bacteria,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GJM	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315	1.1.1.305,2.1.2.13,5.1.3.2	ko:K01784,ko:K10011	ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503	M00361,M00362,M00632,M00721,M00761	R00291,R02984,R07658,R07660	RC00026,RC00289,RC01575,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO2420,iSFV_1184.SFV_2325	Epimerase,Formyl_trans_C,Formyl_trans_N
CMS3_k127_65271_20	237368.SCABRO_03082	1.024e-89	325.0	COG0463@1|root,COG0463@2|Bacteria,2IXAV@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_65271_16	269799.Gmet_0886	6.287e-103	372.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_65271_15	479432.Sros_2090	2.893e-111	364.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4EFK1@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_65271_7	1499686.BN1079_03387	1.828e-174	562.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPZ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_65271_1	1301098.PKB_4315	2.342e-204	651.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_65271_9	1123320.KB889687_gene937	3.963e-151	535.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_65271_41	932678.THERU_04040	0.0001156	55.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_65271_34	1030157.AFMP01000009_gene3648	3.911e-38	152.0	COG1309@1|root,COG1309@2|Bacteria,1RCFF@1224|Proteobacteria,2UB62@28211|Alphaproteobacteria,2KDHX@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
CMS3_k127_65271_24	1121374.KB891575_gene1044	1.28e-74	278.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,1RXYY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_65271_8	685727.REQ_42280	1.352e-155	532.0	COG0318@1|root,COG0318@2|Bacteria,2I8TA@201174|Actinobacteria,4G01M@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K12507	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_65271_5	640512.BC1003_5624	1.493e-181	620.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHII@28216|Betaproteobacteria,1KIDY@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_65271_35	118173.KB235914_gene773	1.005e-37	156.0	COG0451@1|root,COG0451@2|Bacteria,1G14S@1117|Cyanobacteria,1H7DX@1150|Oscillatoriales	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_65271_0	448385.sce5328	2.822e-303	941.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2YWT1@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
CMS3_k127_65271_22	305700.B447_09333	1.289e-84	295.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VIH8@28216|Betaproteobacteria,2KZ85@206389|Rhodocyclales	206389|Rhodocyclales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_65271_37	196490.AUEZ01000002_gene4302	1.074e-35	151.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria,3JR8H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_65271_25	1123320.KB889585_gene1767	9.555e-68	262.0	COG2141@1|root,COG2141@2|Bacteria,2I9FZ@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_65271_32	1123367.C666_15095	1.699e-45	170.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_4
CMS3_k127_65271_31	279238.Saro_3640	7.268e-46	189.0	COG1082@1|root,COG1082@2|Bacteria,1NISG@1224|Proteobacteria,2UP2S@28211|Alphaproteobacteria,2KCCE@204457|Sphingomonadales	204457|Sphingomonadales	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_65271_36	448385.sce1439	8.584e-36	156.0	COG0477@1|root,COG2814@2|Bacteria,1R56E@1224|Proteobacteria,43ARN@68525|delta/epsilon subdivisions,2X65N@28221|Deltaproteobacteria,2Z394@29|Myxococcales	1224|Proteobacteria	EGP	Permease of the major facilitator superfamily	mmlH	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
CMS3_k127_65271_42	1279038.KB907343_gene2513	0.0002161	53.0	2BZNP@1|root,30717@2|Bacteria,1REWN@1224|Proteobacteria,2U7X0@28211|Alphaproteobacteria,2JSDR@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
CMS3_k127_65271_38	383372.Rcas_4358	4.582e-29	136.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi,3763C@32061|Chloroflexia	32061|Chloroflexia	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS3_k127_65271_6	1177179.A11A3_02637	1.078e-178	573.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T251@1236|Gammaproteobacteria,1XJTT@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_65271_33	190650.CC_2085	2.009e-41	161.0	COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,2U5SU@28211|Alphaproteobacteria,2KIJM@204458|Caulobacterales	204458|Caulobacterales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_3,GST_N_3
CMS3_k127_65271_39	1288083.AUKR01000014_gene2873	2.965e-25	122.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
CMS3_k127_6586302_0	1125863.JAFN01000001_gene2828	4.849e-91	310.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43AW1@68525|delta/epsilon subdivisions,2X6A7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6586302_1	667014.Thein_0858	8.033e-59	231.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,2GIEA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_6586302_3	1232410.KI421412_gene200	2.269e-31	139.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,43SES@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_6586302_2	767817.Desgi_1820	6.861e-53	213.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS3_k127_6596580_9	523791.Kkor_1008	6.128e-35	149.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1S07F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_6596580_18	886293.Sinac_1864	4.119e-09	70.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CMS3_k127_6596580_4	335543.Sfum_0758	2.935e-78	291.0	COG4775@1|root,COG4775@2|Bacteria,1QX52@1224|Proteobacteria,43CEZ@68525|delta/epsilon subdivisions,2X7PY@28221|Deltaproteobacteria,2MRBQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_6596580_14	1183438.GKIL_4015	6.094e-18	101.0	COG2911@1|root,COG2911@2|Bacteria,1G1RU@1117|Cyanobacteria	1117|Cyanobacteria	U	Family of	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	DUF748,TamB
CMS3_k127_6596580_5	550540.Fbal_2999	3.166e-55	209.0	2DBFB@1|root,2Z8XA@2|Bacteria,1MVTN@1224|Proteobacteria,1RM97@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4056)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4056
CMS3_k127_6596580_20	1128421.JAGA01000003_gene2825	0.0004457	53.0	2EM0B@1|root,33EPU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6596580_8	1123279.ATUS01000001_gene2636	6.704e-42	158.0	COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria,1S6QM@1236|Gammaproteobacteria,1J9ZC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_6596580_12	1283300.ATXB01000001_gene399	9.989e-23	110.0	2DKXW@1|root,30TMD@2|Bacteria,1R3IE@1224|Proteobacteria,1SPK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4410)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4410
CMS3_k127_6596580_17	123214.PERMA_0410	1.151e-09	70.0	COG2010@1|root,COG2010@2|Bacteria,2G55S@200783|Aquificae	200783|Aquificae	C	Cytochrome c class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_6596580_16	864051.BurJ1DRAFT_4979	1.497e-13	84.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,1KJYZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
CMS3_k127_6596580_10	1229780.BN381_450062	1.695e-28	132.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS3_k127_6596580_2	1353531.AZNX01000001_gene2563	4.735e-109	380.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_8
CMS3_k127_6596580_0	1278073.MYSTI_07874	3.07e-288	931.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria,439FZ@68525|delta/epsilon subdivisions,2X4RS@28221|Deltaproteobacteria,2YZGC@29|Myxococcales	28221|Deltaproteobacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6596580_19	675635.Psed_6431	4.227e-05	57.0	COG0745@1|root,COG0745@2|Bacteria,2I2Z1@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_6596580_6	665571.STHERM_c17700	4.557e-51	193.0	COG0508@1|root,COG0508@2|Bacteria,2J5U3@203691|Spirochaetes	203691|Spirochaetes	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
CMS3_k127_6596580_11	1128421.JAGA01000002_gene653	3.46e-25	110.0	2E5G6@1|root,3307V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SseB
CMS3_k127_6596580_13	382464.ABSI01000005_gene1162	1.267e-19	100.0	2E0ZB@1|root,32WFN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6596580_7	1499968.TCA2_5321	3.359e-47	179.0	COG1028@1|root,COG1028@2|Bacteria,1TSJI@1239|Firmicutes,4HG70@91061|Bacilli,271AW@186822|Paenibacillaceae	91061|Bacilli	IQ	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_6596580_3	298654.FraEuI1c_3877	7.534e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4EU5K@85013|Frankiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_6596580_1	298653.Franean1_3692	7.997e-125	414.0	COG2124@1|root,COG2124@2|Bacteria,2GNZS@201174|Actinobacteria,4EUB3@85013|Frankiales	201174|Actinobacteria	Q	PFAM Cytochrome P450	cyp150A5	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_6624983_4	1502850.FG91_02707	1.462e-37	151.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2U67J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_6624983_0	349521.HCH_04995	8.874e-202	652.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1XMDW@135619|Oceanospirillales	135619|Oceanospirillales	M	dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
CMS3_k127_6624983_1	1380390.JIAT01000010_gene4575	1.338e-112	388.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_6624983_8	204669.Acid345_0673	1.8e-07	63.0	2C5W2@1|root,33IGR@2|Bacteria,3Y8EW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6624983_6	1121949.AQXT01000002_gene1162	2.027e-28	124.0	2E7Y2@1|root,332CH@2|Bacteria,1ND32@1224|Proteobacteria,2UGXT@28211|Alphaproteobacteria,43ZY4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
CMS3_k127_6624983_7	479434.Sthe_3154	7.332e-16	92.0	COG1108@1|root,COG1108@2|Bacteria,2G5VY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K11708	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
CMS3_k127_6624983_3	404589.Anae109_1536	3.925e-47	188.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
CMS3_k127_6624983_2	247490.KSU1_D0783	1.788e-66	243.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS3_k127_6624983_5	1121015.N789_12580	7.884e-32	141.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,1RZ3M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6627132_4	391619.PGA1_262p00430	1.27e-24	120.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,2TQQW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	xylF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
CMS3_k127_6627132_2	1313172.YM304_15130	1.663e-98	334.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_6627132_1	1030157.AFMP01000009_gene3630	2.2e-159	518.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2V9TA@28211|Alphaproteobacteria,2K3K3@204457|Sphingomonadales	204457|Sphingomonadales	C	Fumarate reductase succinate dehydrogenase flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
CMS3_k127_6627132_0	502025.Hoch_2012	5.89e-168	550.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2WJXV@28221|Deltaproteobacteria,2YYSQ@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CMS3_k127_6627132_3	502025.Hoch_2011	5.402e-29	135.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2WQHJ@28221|Deltaproteobacteria,2Z109@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
CMS3_k127_6627132_5	344747.PM8797T_31438	2.088e-11	78.0	COG2268@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG4254@1|root,COG4932@1|root,COG5276@1|root,COG2268@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4254@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
CMS3_k127_6643897_4	234267.Acid_7336	9.164e-100	338.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_6643897_5	331869.BAL199_03474	2.773e-69	264.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2VF6Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_6643897_2	1082933.MEA186_06797	3.091e-165	534.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CMS3_k127_6643897_1	649638.Trad_0121	1.666e-166	535.0	COG0160@1|root,COG0160@2|Bacteria,1WJ8V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_6643897_3	1313172.YM304_16810	7.337e-106	375.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS3_k127_6643897_6	926550.CLDAP_13130	2.93e-57	221.0	COG3153@1|root,COG3153@2|Bacteria,2G8MF@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_6643897_0	234267.Acid_7336	2.541e-170	552.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_6721713_42	398527.Bphyt_4553	4.471e-07	51.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VVIW@28216|Betaproteobacteria,1K73H@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_6721713_10	1219035.NT2_11_00210	3.627e-144	474.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,2JZUE@204457|Sphingomonadales	204457|Sphingomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
CMS3_k127_6721713_1	1122247.C731_0306	1.436e-221	721.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,232CR@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6721713_4	164757.Mjls_3748	1.135e-168	557.0	COG3173@1|root,COG3173@2|Bacteria,2GJ58@201174|Actinobacteria,2335Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_6721713_14	1078020.KEK_18173	6.355e-127	414.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,235GY@1762|Mycobacteriaceae	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_6721713_15	365528.KB891226_gene1281	4.114e-121	406.0	COG1028@1|root,COG1028@2|Bacteria,2GKJD@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_6721713_3	298654.FraEuI1c_4128	6.736e-170	551.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4ESDV@85013|Frankiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6721713_39	1282876.BAOK01000001_gene3538	7e-17	87.0	2DVUV@1|root,33XA1@2|Bacteria,1NW6A@1224|Proteobacteria	1224|Proteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_6721713_21	1278073.MYSTI_04824	3.515e-81	282.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,437H0@68525|delta/epsilon subdivisions,2X2QC@28221|Deltaproteobacteria,2YXMK@29|Myxococcales	28221|Deltaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_6721713_33	1217720.ALOX01000019_gene751	8.171e-46	181.0	COG0673@1|root,COG0673@2|Bacteria,1R4SZ@1224|Proteobacteria,2TRR2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_6721713_25	1463856.JOHY01000004_gene6441	3.645e-66	255.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_6721713_41	1185766.DL1_20135	4.7e-09	68.0	COG3914@1|root,COG3914@2|Bacteria,1QU3U@1224|Proteobacteria	1224|Proteobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
CMS3_k127_6721713_35	316274.Haur_3582	2.872e-30	136.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_6721713_43	1123279.ATUS01000001_gene2055	3.967e-06	60.0	2A1UR@1|root,30Q3W@2|Bacteria,1Q739@1224|Proteobacteria,1SQN8@1236|Gammaproteobacteria,1JAQA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6721713_27	391625.PPSIR1_21729	2.304e-52	207.0	COG0277@1|root,COG0277@2|Bacteria,1QZTK@1224|Proteobacteria,43CNH@68525|delta/epsilon subdivisions,2X7VU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
CMS3_k127_6721713_6	1041139.KB902646_gene3418	8.847e-167	567.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1,SAM_2
CMS3_k127_6721713_8	247634.GPB2148_1943	3.736e-146	515.0	COG0613@1|root,COG0613@2|Bacteria,1R4N5@1224|Proteobacteria	1224|Proteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6721713_11	247634.GPB2148_1943	1.573e-143	499.0	COG0613@1|root,COG0613@2|Bacteria,1R4N5@1224|Proteobacteria	1224|Proteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6721713_24	479434.Sthe_2336	1.126e-67	236.0	COG2258@1|root,COG2258@2|Bacteria,2G7HE@200795|Chloroflexi,27YRB@189775|Thermomicrobia	189775|Thermomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS3_k127_6721713_37	715451.ambt_06080	3.328e-23	118.0	28HBN@1|root,2Z7NM@2|Bacteria,1NXQY@1224|Proteobacteria,1SBXN@1236|Gammaproteobacteria,46C85@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6721713_31	582515.KR51_00014290	1.611e-47	198.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2912 conserved	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
CMS3_k127_6721713_0	756272.Plabr_3518	1.953e-281	908.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CMS3_k127_6721713_44	378806.STAUR_7790	7.527e-06	56.0	COG2314@1|root,COG2314@2|Bacteria	2|Bacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
CMS3_k127_6721713_9	471853.Bcav_2121	1.304e-144	471.0	COG3568@1|root,COG3568@2|Bacteria,2I41W@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_6721713_12	266117.Rxyl_0960	1.329e-139	453.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CSEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS3_k127_6721713_16	402881.Plav_2640	3.474e-108	362.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRIH@28211|Alphaproteobacteria,1JQ49@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_16365	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
CMS3_k127_6721713_28	1313172.YM304_29270	2.588e-51	200.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
CMS3_k127_6721713_17	189753.AXAS01000003_gene4770	9.857e-102	372.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,3JRG7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_6721713_22	1121920.AUAU01000011_gene183	1.497e-75	276.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,3Y85P@57723|Acidobacteria	57723|Acidobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,Guanylate_cyc
CMS3_k127_6721713_40	1273125.Rrhod_2241	1.375e-16	89.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4G0P0@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_6721713_46	1155718.KB891884_gene6090	0.0002331	52.0	COG1309@1|root,COG1309@2|Bacteria,2GJZJ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6721713_45	1415780.JPOG01000001_gene3370	8.484e-06	57.0	2C945@1|root,30HM7@2|Bacteria,1R3I3@1224|Proteobacteria,1S50Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	5.4.4.1	ko:K01865	ko00627,ko01120,map00627,map01120	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_6721713_38	1229780.BN381_130239	2.564e-19	96.0	COG0662@1|root,COG0662@2|Bacteria,2GYFJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_6721713_23	344747.PM8797T_04335	5.14e-70	255.0	COG3119@1|root,COG3119@2|Bacteria,2J2Z5@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_6721713_2	1313172.YM304_41890	6.843e-206	652.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6721713_18	471852.Tcur_2583	3.65e-100	341.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_6721713_36	247634.GPB2148_230	3.37e-30	129.0	COG1309@1|root,COG1309@2|Bacteria,1PIS9@1224|Proteobacteria,1SFRX@1236|Gammaproteobacteria,1J6YQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6721713_32	402881.Plav_3100	1.942e-47	192.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	paaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
CMS3_k127_6721713_13	402881.Plav_2614	2.568e-130	453.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2VCQC@28211|Alphaproteobacteria,1JQ8P@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_6721713_19	1463917.JODC01000002_gene886	6.34e-100	353.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
CMS3_k127_6721713_26	998674.ATTE01000001_gene2373	1.338e-59	222.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1SZQ8@1236|Gammaproteobacteria,46328@72273|Thiotrichales	72273|Thiotrichales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_6721713_7	1230343.CANP01000046_gene3647	1.265e-151	492.0	COG0827@1|root,COG0827@2|Bacteria,1QYXX@1224|Proteobacteria,1SKI5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6721713_29	1158318.ATXC01000001_gene1055	5.418e-51	183.0	COG0347@1|root,COG0347@2|Bacteria,2G43N@200783|Aquificae	200783|Aquificae	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_6721713_5	1178825.ALIH01000003_gene2086	7.24e-168	539.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1HYDV@117743|Flavobacteriia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS3_k127_6721713_20	1313172.YM304_06500	6.131e-94	317.0	COG2141@1|root,COG2141@2|Bacteria,2H89R@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_6721713_30	1408418.JNJH01000008_gene2531	5.509e-50	199.0	COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,2U7MV@28211|Alphaproteobacteria,2JT3X@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_673900_12	1160137.KB907308_gene6991	4.416e-60	219.0	COG2084@1|root,COG2084@2|Bacteria,2GTGE@201174|Actinobacteria,4G4IQ@85025|Nocardiaceae	201174|Actinobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,F420_oxidored,NAD_binding_2
CMS3_k127_673900_7	1278073.MYSTI_04828	2.363e-99	352.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_673900_13	247633.GP2143_02804	4.749e-55	204.0	COG2030@1|root,COG2030@2|Bacteria,1NYEM@1224|Proteobacteria	1224|Proteobacteria	I	dehydratase	MA20_27475	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_673900_16	1415166.NONO_c18200	5.143e-49	188.0	COG5285@1|root,COG5285@2|Bacteria,2GNXP@201174|Actinobacteria,4FVHP@85025|Nocardiaceae	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_673900_6	1192034.CAP_6511	1.144e-130	447.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS3_k127_673900_23	1123242.JH636434_gene3210	7.418e-12	79.0	2E19R@1|root,32WPZ@2|Bacteria,2J1EK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_673900_1	316057.RPD_3848	4.301e-202	642.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,2U0T4@28211|Alphaproteobacteria,3JRE4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_673900_25	1123242.JH636434_gene3210	1.98e-05	57.0	2E19R@1|root,32WPZ@2|Bacteria,2J1EK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_673900_4	1122939.ATUD01000001_gene577	1.415e-163	553.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_673900_8	448385.sce8980	9.979e-99	347.0	COG1835@1|root,COG1835@2|Bacteria,1REU1@1224|Proteobacteria,43AB0@68525|delta/epsilon subdivisions,2X9CR@28221|Deltaproteobacteria,2Z1T7@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS3_k127_673900_5	1282360.ABAC460_18945	5.915e-141	463.0	COG0673@1|root,COG0673@2|Bacteria,1QSNV@1224|Proteobacteria,2TUMB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_673900_10	1265310.CCBD010000014_gene3774	3.405e-73	257.0	COG3246@1|root,COG3246@2|Bacteria,2I9EQ@201174|Actinobacteria,238IV@1762|Mycobacteriaceae	201174|Actinobacteria	S	beta-keto acid cleavage enzyme	kce_2	-	-	-	-	-	-	-	-	-	-	-	BKACE
CMS3_k127_673900_19	7260.FBpp0254677	1.463e-27	132.0	COG1028@1|root,KOG1200@2759|Eukaryota,39S00@33154|Opisthokonta,3BGVB@33208|Metazoa,3CXFR@33213|Bilateria,41YDY@6656|Arthropoda,3SHD5@50557|Insecta,44XHI@7147|Diptera,45STK@7214|Drosophilidae	33208|Metazoa	Q	Oxidoreductase activity. It is involved in the biological process described with metabolic process	-	-	1.1.1.239,1.1.1.62	ko:K13370	ko00140,ko01100,map00140,map01100	-	R01836,R02352,R02353,R04681,R04682,R08945,R08980	RC00127,RC00261	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS3_k127_673900_9	1168065.DOK_02156	5.977e-94	317.0	COG2141@1|root,COG2141@2|Bacteria,1QE9J@1224|Proteobacteria,1S0QV@1236|Gammaproteobacteria,1J5M9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_673900_3	1168059.KB899087_gene3833	5.412e-178	568.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,2U4VR@28211|Alphaproteobacteria,3F0QU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS3_k127_673900_17	227882.SAV_6798	2.07e-44	186.0	COG1051@1|root,COG1051@2|Bacteria,2IICP@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_673900_0	1205680.CAKO01000037_gene1298	0.0	1341.0	COG0439@1|root,COG1038@1|root,COG4799@1|root,COG0439@2|Bacteria,COG1038@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria,2JZ2C@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
CMS3_k127_673900_11	298655.KI912266_gene3894	6.862e-61	219.0	COG1051@1|root,COG1051@2|Bacteria,2IK26@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_673900_2	479434.Sthe_3255	1.939e-184	597.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_673900_22	1254432.SCE1572_07825	8.065e-13	78.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_673900_20	1303518.CCALI_00669	4.519e-22	106.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
CMS3_k127_673900_24	1168065.DOK_15249	1.489e-05	55.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1J4BY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_673900_15	1394178.AWOO02000001_gene1326	2.789e-50	194.0	COG2159@1|root,COG2159@2|Bacteria,2H2CJ@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_673900_14	42256.RradSPS_2095	4.137e-52	200.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CR6S@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS3_k127_673900_21	420662.Mpe_A1045	1.324e-18	93.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,1KKUU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_N
CMS3_k127_673900_18	448385.sce0675	6.26e-36	153.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,437UU@68525|delta/epsilon subdivisions,2WYPC@28221|Deltaproteobacteria,2YU77@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_6750416_5	338966.Ppro_0511	2.394e-64	230.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS3_k127_6750416_11	69014.TK2264	1.704e-11	79.0	COG1800@1|root,arCOG07561@1|root,arCOG02164@2157|Archaea,arCOG07561@2157|Archaea,2XV3J@28890|Euryarchaeota,2435K@183968|Thermococci	183968|Thermococci	K	Transglutaminase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF553
CMS3_k127_6750416_9	671143.DAMO_0223	4.8e-13	85.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CMS3_k127_6750416_3	1535422.ND16A_2150	9.796e-119	433.0	COG3485@1|root,COG4932@1|root,COG5276@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,CarboxypepD_reg,DUF11,FG-GAP
CMS3_k127_6750416_10	1188252.AJYK01000033_gene1029	2.846e-12	79.0	COG2831@1|root,COG2831@2|Bacteria,1R2TR@1224|Proteobacteria,1SZV1@1236|Gammaproteobacteria,1Y2X7@135623|Vibrionales	135623|Vibrionales	U	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_6750416_1	1254432.SCE1572_38935	3.111e-175	561.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,42MMZ@68525|delta/epsilon subdivisions,2WJF0@28221|Deltaproteobacteria,2YWP5@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_6750416_8	1205680.CAKO01000038_gene1780	9.502e-37	151.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VGB7@28211|Alphaproteobacteria,2JYRY@204441|Rhodospirillales	204441|Rhodospirillales	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
CMS3_k127_6750416_4	502025.Hoch_2465	2.625e-90	322.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2YZ69@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS3_k127_6750416_7	102232.GLO73106DRAFT_00033170	2.837e-49	190.0	COG0631@1|root,COG0631@2|Bacteria,1G2FY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM protein phosphatase 2C	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_6750416_0	1254432.SCE1572_26495	8.272e-264	850.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2YUGZ@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
CMS3_k127_6750416_12	1210884.HG799462_gene8540	1.647e-09	68.0	2DPBR@1|root,331ES@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6750416_2	448385.sce0599	1.372e-119	404.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,42NZ1@68525|delta/epsilon subdivisions,2WNX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
CMS3_k127_6750416_6	644966.Tmar_2315	2.039e-57	209.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3WD43@538999|Clostridiales incertae sedis	186801|Clostridia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS3_k127_6750416_13	1121949.AQXT01000002_gene1905	4.097e-05	53.0	COG1216@1|root,COG1216@2|Bacteria,1R6SJ@1224|Proteobacteria,2U47V@28211|Alphaproteobacteria,43W7J@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_6772785_0	1123229.AUBC01000006_gene986	5.857e-58	220.0	COG1252@1|root,COG1252@2|Bacteria,1QUKT@1224|Proteobacteria,2TW32@28211|Alphaproteobacteria,3JZTJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
CMS3_k127_6801533_7	344747.PM8797T_19345	4.098e-05	46.0	COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes	203682|Planctomycetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_6801533_0	1449976.KALB_3416	4.203e-115	386.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4DX4S@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_6801533_5	1297863.APJF01000010_gene3487	1.979e-28	132.0	COG2050@1|root,COG2050@2|Bacteria,1N57X@1224|Proteobacteria,2TVFU@28211|Alphaproteobacteria,3JS6X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
CMS3_k127_6801533_6	502025.Hoch_6850	1.7e-06	62.0	COG0625@1|root,COG0625@2|Bacteria,1PG5Y@1224|Proteobacteria,435HT@68525|delta/epsilon subdivisions,2WZVH@28221|Deltaproteobacteria,2Z2U4@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	-
CMS3_k127_6801533_3	272134.KB731324_gene6143	1.647e-46	179.0	COG2755@1|root,COG2755@2|Bacteria,1G70I@1117|Cyanobacteria	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_6801533_1	266117.Rxyl_3181	5.798e-91	309.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CU2F@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_6801533_2	197221.22295147	4.256e-62	241.0	COG0412@1|root,COG0412@2|Bacteria,1G0PH@1117|Cyanobacteria	1117|Cyanobacteria	Q	dienelactone hydrolase	clcD	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS3_k127_6801533_4	290397.Adeh_3462	2.261e-35	148.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42P5F@68525|delta/epsilon subdivisions,2WM2S@28221|Deltaproteobacteria,2Z310@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_6818998_9	335543.Sfum_3617	8.828e-07	58.0	COG1842@1|root,COG1842@2|Bacteria,1Q6II@1224|Proteobacteria,43383@68525|delta/epsilon subdivisions,2WY57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM PspA IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS3_k127_6818998_3	335543.Sfum_3616	1.216e-55	214.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_6818998_2	335543.Sfum_3615	2.18e-58	212.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,42QRX@68525|delta/epsilon subdivisions,2WN2D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_6818998_1	335543.Sfum_3614	5.169e-65	254.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CFM@68525|delta/epsilon subdivisions,2X7QN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_6818998_7	247634.GPB2148_1645	2.647e-35	151.0	COG2771@1|root,COG2771@2|Bacteria,1MWC0@1224|Proteobacteria,1RSD4@1236|Gammaproteobacteria,1J4PU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS3_k127_6818998_8	1415756.JQMY01000001_gene369	2.104e-21	96.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,2UCCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lipid A Biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
CMS3_k127_6818998_6	479432.Sros_6660	6.017e-44	174.0	2BXSN@1|root,2ZAB3@2|Bacteria,2I1VJ@201174|Actinobacteria,4EPCA@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
CMS3_k127_6818998_0	1382356.JQMP01000003_gene1909	3.331e-110	369.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS3_k127_6818998_5	1500306.JQLA01000014_gene1938	9.91e-46	180.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,4B7XG@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS3_k127_6818998_4	290397.Adeh_1406	3.252e-50	191.0	COG0249@1|root,COG0249@2|Bacteria,1N9K4@1224|Proteobacteria,42ZN5@68525|delta/epsilon subdivisions,2WUW7@28221|Deltaproteobacteria,2YTSE@29|Myxococcales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
CMS3_k127_6855015_17	43759.JNWK01000017_gene7585	9.159e-08	60.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_6855015_11	1105031.HMPREF1141_1538	3.335e-26	124.0	2EVDG@1|root,33NTX@2|Bacteria,1VP1F@1239|Firmicutes,24SI4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6855015_9	443152.MDG893_17452	4.417e-38	165.0	COG3687@1|root,COG3687@2|Bacteria,1R74T@1224|Proteobacteria,1RZES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07044	-	-	-	-	ko00000	-	-	-	Metal_hydrol
CMS3_k127_6855015_14	1415754.JQMK01000002_gene2371	1.116e-21	109.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,4672V@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2829 Outer membrane phospholipase A	pldA	GO:0003674,GO:0003824,GO:0004620,GO:0004623,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0008970,GO:0009279,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044462,GO:0044464,GO:0045203,GO:0046872,GO:0046983,GO:0052689,GO:0071944	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_4201,iECUMN_1333.ECUMN_4347,iEcSMS35_1347.EcSMS35_4188	PLA1
CMS3_k127_6855015_16	1202962.KB907159_gene3363	8.293e-10	65.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_6855015_10	1237500.ANBA01000008_gene370	1.219e-35	145.0	COG0030@1|root,COG0030@2|Bacteria,2H1TK@201174|Actinobacteria,4EHUQ@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermSF	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
CMS3_k127_6855015_18	1211115.ALIQ01000230_gene1647	2.166e-05	59.0	COG2982@1|root,COG2982@2|Bacteria,1MUNH@1224|Proteobacteria,2TT0W@28211|Alphaproteobacteria,3NA3G@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	AsmA family	asmA	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CMS3_k127_6855015_5	768671.ThimaDRAFT_2764	1.074e-79	299.0	COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,1S3FR@1236|Gammaproteobacteria,1X02B@135613|Chromatiales	135613|Chromatiales	E	PFAM N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS3_k127_6855015_0	765911.Thivi_2306	1.699e-142	458.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,1RRMA@1236|Gammaproteobacteria,1WWEH@135613|Chromatiales	135613|Chromatiales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
CMS3_k127_6855015_2	1205680.CAKO01000002_gene3078	2.373e-128	430.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2JPND@204441|Rhodospirillales	204441|Rhodospirillales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_6855015_1	1123320.KB889686_gene721	1.219e-129	442.0	COG0318@1|root,COG0318@2|Bacteria,2IE11@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6855015_7	1123320.KB889686_gene728	9.287e-39	167.0	COG1309@1|root,COG1309@2|Bacteria,2IAMN@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6855015_8	35754.JNYJ01000003_gene6557	2.516e-38	159.0	COG1014@1|root,COG1014@2|Bacteria,2GUYE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS3_k127_6855015_13	1116369.KB890024_gene1763	1.765e-23	111.0	COG1146@1|root,COG1146@2|Bacteria,1NGPS@1224|Proteobacteria	1224|Proteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4
CMS3_k127_6855015_3	1123320.KB889686_gene725	1.37e-113	385.0	COG0674@1|root,COG0674@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS3_k127_6855015_4	1123320.KB889686_gene724	1.806e-95	339.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_6855015_15	247156.NFA_34980	9.827e-14	78.0	2E7VU@1|root,332AK@2|Bacteria,2IQ82@201174|Actinobacteria,4G312@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_6855015_6	1232410.KI421428_gene1084	2.366e-50	194.0	COG0491@1|root,COG0491@2|Bacteria,1NMU0@1224|Proteobacteria,432WR@68525|delta/epsilon subdivisions,2WY8W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
CMS3_k127_6855015_19	235985.BBPN01000021_gene6374	0.0009704	51.0	2C5EX@1|root,2ZCYR@2|Bacteria,2HAW7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_685545_7	745718.JADT01000023_gene1431	1.246e-65	242.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,FG-GAP_2,LVIVD
CMS3_k127_685545_1	330214.NIDE1873	1.166e-144	495.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
CMS3_k127_685545_13	1519464.HY22_06675	1.51e-36	146.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,AhpC-TSA_2
CMS3_k127_685545_5	114615.BRADO6500	3.638e-98	339.0	COG2130@1|root,COG2130@2|Bacteria,1MUR0@1224|Proteobacteria,2U16B@28211|Alphaproteobacteria,3JSRG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
CMS3_k127_685545_0	686340.Metal_0317	8.727e-154	507.0	COG1749@1|root,COG2372@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Big_5,DUF4082,Flg_bb_rod,Flg_bbr_C,SASA
CMS3_k127_685545_17	42256.RradSPS_0637	2.309e-11	78.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_685545_10	1446473.JHWH01000039_gene3502	1.26e-51	196.0	28IG7@1|root,2Z8FZ@2|Bacteria,1R3PR@1224|Proteobacteria,2UB1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YfdX protein	-	-	-	-	-	-	-	-	-	-	-	-	YfdX
CMS3_k127_685545_9	298655.KI912266_gene2271	1.5e-55	210.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CMS3_k127_685545_6	118005.AWNK01000006_gene1234	4.272e-83	306.0	COG0475@1|root,COG1762@1|root,COG0475@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	Na_H_Exchanger,PTS_EIIA_2,Usp
CMS3_k127_685545_2	1382306.JNIM01000001_gene623	5.834e-108	362.0	COG2124@1|root,COG2124@2|Bacteria,2G7SX@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_685545_3	1219035.NT2_09_00200	9.986e-103	342.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,2TU6B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_685545_8	754477.Q7C_1390	7.072e-60	217.0	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
CMS3_k127_685545_4	472759.Nhal_3760	2.424e-100	364.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1X07Q@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_685545_16	105559.Nwat_2487	6.549e-17	89.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1X15P@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_685545_11	1333856.L686_05350	5.408e-41	163.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria,1Z2VP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	U	TonB system transport protein ExbD	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_685545_15	1323663.AROI01000013_gene216	8.023e-18	96.0	COG0810@1|root,COG0810@2|Bacteria,1NH16@1224|Proteobacteria,1S2FT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_685545_14	1415779.JOMH01000001_gene335	2.184e-34	151.0	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1X6YK@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_685545_12	1125863.JAFN01000001_gene972	9.039e-39	157.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS3_k127_6909457_13	2074.JNYD01000034_gene6437	9.47e-13	76.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_6909457_14	1121272.KB903250_gene2909	2.982e-09	68.0	2C56P@1|root,2ZJ2W@2|Bacteria,2IKDI@201174|Actinobacteria,4DDQZ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6909457_11	521674.Plim_0216	1.37e-29	125.0	COG1999@1|root,COG2322@1|root,COG1999@2|Bacteria,COG2322@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
CMS3_k127_6909457_10	382464.ABSI01000010_gene3670	7.535e-46	179.0	COG2863@1|root,COG2863@2|Bacteria,46WZQ@74201|Verrucomicrobia,2IW1M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_6909457_7	382464.ABSI01000010_gene3669	2.503e-70	245.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia,2IU8P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	COX2
CMS3_k127_6909457_0	382464.ABSI01000010_gene3668	1.663e-269	842.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,2ITKY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CMS3_k127_6909457_8	382464.ABSI01000010_gene3667	6.038e-63	222.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,2IU4E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c oxidase subunit III	-	-	-	-	-	-	-	-	-	-	-	-	COX3
CMS3_k127_6909457_9	382464.ABSI01000010_gene3665	6.983e-51	186.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS3_k127_6909457_4	1280949.HAD_00915	4.108e-109	372.0	COG2159@1|root,COG2159@2|Bacteria,1MVTS@1224|Proteobacteria,2VGQX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_6909457_1	1313172.YM304_34560	1.214e-156	509.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria	201174|Actinobacteria	Q	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
CMS3_k127_6909457_15	1304880.JAGB01000002_gene1810	4.717e-07	63.0	COG2211@1|root,COG2211@2|Bacteria,1TRCV@1239|Firmicutes,24CK5@186801|Clostridia	186801|Clostridia	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_6909457_5	402881.Plav_1806	4.502e-92	331.0	COG1960@1|root,COG1960@2|Bacteria,1R7HF@1224|Proteobacteria,2U3BJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_6909457_2	314225.ELI_14975	2.846e-152	511.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6909457_3	1172181.KB911746_gene5556	8.156e-112	399.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,PD40
CMS3_k127_6909457_6	1173024.KI912148_gene2500	7.567e-71	250.0	COG1413@1|root,COG1413@2|Bacteria,1G3ZC@1117|Cyanobacteria	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_6930255_8	36809.MAB_1379c	6.767e-09	65.0	COG1309@1|root,COG1309@2|Bacteria,2IFV0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6930255_0	216594.MMAR_0138	9.998e-129	423.0	COG2159@1|root,COG2159@2|Bacteria,2GMRC@201174|Actinobacteria,2371C@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_6930255_3	1267534.KB906754_gene3500	2.86e-107	364.0	COG0399@1|root,COG0399@2|Bacteria,3Y2G1@57723|Acidobacteria,2JI3T@204432|Acidobacteriia	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	ntdA	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.104	ko:K18653	-	-	R10698	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_6930255_2	644282.Deba_0355	2.867e-112	372.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42XX1@68525|delta/epsilon subdivisions,2WTAH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6930255_4	35754.JNYJ01000001_gene7218	2.327e-99	347.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4DD8D@85008|Micromonosporales	201174|Actinobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep,Hexapep_2
CMS3_k127_6930255_5	1499967.BAYZ01000125_gene2598	4.914e-48	198.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
CMS3_k127_6930255_7	1054213.HMPREF9946_03720	2.089e-32	143.0	COG2246@1|root,COG2246@2|Bacteria,1QUSS@1224|Proteobacteria,2TW63@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6930255_1	502025.Hoch_5221	1.304e-117	390.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2YTVB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS3_k127_6930255_6	760568.Desku_3526	2.005e-36	155.0	COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,24C1C@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_6944595_1	1123322.KB904647_gene1682	2.846e-121	403.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE16	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6944595_0	1229780.BN381_210093	8.005e-131	428.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,3UXCB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6944595_2	118005.AWNK01000001_gene1885	4.127e-08	68.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,VCBS
CMS3_k127_6945891_1	946483.Cenrod_1680	7.702e-09	67.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AGV1@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS_3,PAS_4,Response_reg
CMS3_k127_6945891_0	335543.Sfum_0219	1.281e-213	679.0	COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_7019677_23	446465.Bfae_04970	1.29e-08	65.0	2E2P7@1|root,32XS5@2|Bacteria,2ISG4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7019677_0	384765.SIAM614_29171	3.037e-275	855.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
CMS3_k127_7019677_22	384765.SIAM614_17709	2.407e-12	74.0	2AGK3@1|root,316T8@2|Bacteria,1NICS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7019677_6	1463901.JOIY01000012_gene19	1.012e-68	247.0	COG0510@1|root,COG0510@2|Bacteria,2GMFN@201174|Actinobacteria	201174|Actinobacteria	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_7019677_21	4529.ORUFI04G30410.1	4.952e-14	84.0	28IIJ@1|root,2QQYU@2759|Eukaryota,37JD1@33090|Viridiplantae,3GHI3@35493|Streptophyta,3KXJP@4447|Liliopsida,3IQ9R@38820|Poales	35493|Streptophyta	S	SAM dependent carboxyl methyltransferase	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0010340,GO:0010341,GO:0016740,GO:0016741,GO:0032259	2.1.1.275,2.1.1.276,2.1.1.278	ko:K18848,ko:K18885,ko:K18886	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_7
CMS3_k127_7019677_16	1396141.BATP01000003_gene5002	1.504e-23	110.0	COG1670@1|root,COG1670@2|Bacteria,46U79@74201|Verrucomicrobia,2IVSC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7019677_4	653045.Strvi_6126	6.318e-78	272.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_7019677_13	698761.RTCIAT899_CH04575	3.135e-34	138.0	COG0346@1|root,COG0346@2|Bacteria,1PW4X@1224|Proteobacteria,2V7BJ@28211|Alphaproteobacteria,4BHUY@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7019677_15	512565.AMIS_580	5.419e-28	125.0	2BWWR@1|root,2ZG0F@2|Bacteria,2IJ2X@201174|Actinobacteria,4DDGM@85008|Micromonosporales	201174|Actinobacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_7019677_14	1000565.METUNv1_03440	1.146e-30	129.0	COG1670@1|root,COG1670@2|Bacteria,1PZTX@1224|Proteobacteria,2W4BT@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_7019677_8	1215092.PA6_016_01260	1.592e-65	252.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_7019677_27	234267.Acid_7494	5.842e-05	57.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7019677_3	1185876.BN8_03375	1.012e-101	354.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47ME9@768503|Cytophagia	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_7019677_24	935848.JAEN01000016_gene2406	7.921e-08	57.0	2EMG7@1|root,33F4W@2|Bacteria,1NIU8@1224|Proteobacteria,2UKE3@28211|Alphaproteobacteria,2PXQX@265|Paracoccus	28211|Alphaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_7019677_2	572477.Alvin_1501	1.853e-104	381.0	COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1WWF0@135613|Chromatiales	135613|Chromatiales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
CMS3_k127_7019677_26	103733.JNYO01000007_gene5157	5.323e-06	51.0	COG0236@1|root,COG0236@2|Bacteria,2HS41@201174|Actinobacteria,4ECAU@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_7019677_1	765911.Thivi_1799	2.837e-112	383.0	COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1WWF0@135613|Chromatiales	135613|Chromatiales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
CMS3_k127_7019677_7	1232428.CAVO010000057_gene1792	1.895e-67	241.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4H26N@909932|Negativicutes	909932|Negativicutes	M	Glycosyltransferase group 2 family protein	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS3_k127_7019677_11	1128421.JAGA01000003_gene3091	3.301e-38	165.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_7019677_9	1267535.KB906767_gene4838	1.668e-51	211.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_7019677_28	1183438.GKIL_1906	0.0001156	54.0	COG3794@1|root,COG3794@2|Bacteria,1GFJP@1117|Cyanobacteria	1117|Cyanobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
CMS3_k127_7019677_18	1454004.AW11_00189	1.107e-16	94.0	2C0Z5@1|root,33MJA@2|Bacteria,1NPZ8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7019677_5	1382306.JNIM01000001_gene725	5.658e-77	267.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_7019677_17	526225.Gobs_4598	1.856e-23	111.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS3_k127_7019677_25	1267533.KB906738_gene2044	2.284e-06	61.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7019677_12	234267.Acid_1770	5.898e-37	157.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
CMS3_k127_7019677_19	1499967.BAYZ01000105_gene3517	4.171e-15	87.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	ChitinaseA_N,Lipase_GDSL_2
CMS3_k127_7023753_0	887062.HGR_04823	4.356e-120	410.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CMS3_k127_7023753_1	1131553.JIBI01000006_gene1072	1.996e-93	323.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2VJ87@28216|Betaproteobacteria,37294@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
CMS3_k127_7023753_2	880073.Calab_1123	1.34e-61	231.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
CMS3_k127_7023753_4	1144275.COCOR_06891	3.389e-18	100.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QX@1224|Proteobacteria,431N8@68525|delta/epsilon subdivisions,2WWXI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
CMS3_k127_7023753_3	196490.AUEZ01000021_gene772	3.642e-20	102.0	COG3777@1|root,COG3777@2|Bacteria,1RIJT@1224|Proteobacteria,2UKZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7076261_21	471852.Tcur_0705	1.616e-18	100.0	COG0517@1|root,COG0517@2|Bacteria,2I26I@201174|Actinobacteria,4EQHS@85012|Streptosporangiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_7076261_17	247490.KSU1_D0807	3.68e-24	117.0	2BRMQ@1|root,32KM4@2|Bacteria,2J4AR@203682|Planctomycetes	247490.KSU1_D0807|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7076261_0	530564.Psta_1753	0.0	1069.0	COG3968@1|root,COG3968@2|Bacteria,2IXF6@203682|Planctomycetes	203682|Planctomycetes	S	Glutamine synthetase type III	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
CMS3_k127_7076261_23	1158292.JPOE01000005_gene1125	3.519e-08	64.0	COG0584@1|root,COG0775@1|root,COG0584@2|Bacteria,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,2VQBX@28216|Betaproteobacteria,1KKNE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_7076261_2	298653.Franean1_6853	1.347e-143	474.0	COG3653@1|root,COG3653@2|Bacteria,2IE6H@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_7076261_19	883126.HMPREF9710_03144	6.66e-20	99.0	COG0454@1|root,COG0456@2|Bacteria,1RKFU@1224|Proteobacteria,2VUBE@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_7076261_6	1040987.AZUY01000013_gene2918	5.952e-100	341.0	COG4409@1|root,COG4409@2|Bacteria,1N7TI@1224|Proteobacteria,2UGE7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_7076261_22	1457250.BBMO01000002_gene2768	3.656e-09	69.0	COG3379@1|root,arCOG01377@2157|Archaea,2XUWW@28890|Euryarchaeota,23RZ5@183963|Halobacteria	183963|Halobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_7076261_15	1121451.DESAM_22028	5.602e-33	148.0	COG1807@1|root,COG1807@2|Bacteria,1QQYT@1224|Proteobacteria,435NZ@68525|delta/epsilon subdivisions,2X02E@28221|Deltaproteobacteria,2M9ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7076261_16	1206744.BAGL01000052_gene2298	3.463e-24	108.0	COG3832@1|root,COG3832@2|Bacteria,2IPG1@201174|Actinobacteria,4G1IB@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_7076261_3	1108045.GORHZ_075_00200	9.446e-137	480.0	COG5361@1|root,COG5361@2|Bacteria,2HES3@201174|Actinobacteria,4GH56@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
CMS3_k127_7076261_8	1112204.GPOL_c47830	2.123e-83	301.0	COG0438@1|root,COG0438@2|Bacteria,2I7GS@201174|Actinobacteria,4GG64@85026|Gordoniaceae	201174|Actinobacteria	M	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_7076261_12	1192034.CAP_3537	7.729e-54	216.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,42TE9@68525|delta/epsilon subdivisions,2WPGF@28221|Deltaproteobacteria,2YUH5@29|Myxococcales	28221|Deltaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_7076261_5	443144.GM21_1432	4.936e-108	387.0	COG2204@1|root,COG3852@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_7076261_1	357808.RoseRS_0965	4.415e-144	464.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,376D2@32061|Chloroflexia	32061|Chloroflexia	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS3_k127_7076261_10	1429916.X566_09935	4.659e-77	268.0	COG0625@1|root,COG0625@2|Bacteria,1MWUG@1224|Proteobacteria,2TTZ6@28211|Alphaproteobacteria,3JSTS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
CMS3_k127_7076261_25	9541.XP_005595967.1	0.0001876	55.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,4832D@7711|Chordata,48VDS@7742|Vertebrata,3J9Q4@40674|Mammalia,35P9M@314146|Euarchontoglires,4MFKU@9443|Primates,35WUD@314294|Cercopithecoidea	33208|Metazoa	T	von Willebrand factor type A domain	MATN4	GO:0005575,GO:0005576,GO:0006950,GO:0008150,GO:0009611,GO:0009987,GO:0016043,GO:0030198,GO:0043062,GO:0048678,GO:0050896,GO:0071840	-	ko:K06825,ko:K17307	-	-	-	-	ko00000,ko00536,ko04147,ko04516	-	-	-	EGF_CA,FXa_inhibition,Matrilin_ccoil,VWA,cEGF
CMS3_k127_7076261_14	1547437.LL06_18050	7.113e-34	152.0	COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,2U3NK@28211|Alphaproteobacteria,43HG7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_7076261_20	285514.JNWO01000001_gene4293	6.315e-19	98.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_7076261_11	2074.JNYD01000003_gene3804	1.114e-71	260.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DZ1Z@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_7076261_4	566461.SSFG_06725	1.287e-122	421.0	COG3173@1|root,COG3173@2|Bacteria,2GN1G@201174|Actinobacteria	201174|Actinobacteria	I	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_7076261_7	566466.NOR53_3546	4.877e-98	342.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1J956@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
CMS3_k127_7076261_13	1116472.MGMO_69c00130	2.347e-36	145.0	COG3917@1|root,COG3917@2|Bacteria,1RDV0@1224|Proteobacteria,1S3P0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_7076261_9	118166.JH976538_gene5057	1.18e-81	303.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
CMS3_k127_7076261_18	246197.MXAN_5683	2.58e-22	115.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,42V8Q@68525|delta/epsilon subdivisions,2WRSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_7080731_6	926560.KE387026_gene4233	6.245e-06	49.0	COG0514@1|root,COG0514@2|Bacteria,1WNC1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Helicase and RNase D C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HRDC
CMS3_k127_7080731_0	1313172.YM304_06080	5.08e-109	360.0	COG5285@1|root,COG5285@2|Bacteria,2I8HN@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_7080731_3	1313172.YM304_06070	8.542e-23	112.0	2DQWS@1|root,32UPZ@2|Bacteria,2IQUC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7080731_4	762376.AXYL_02127	1.697e-15	88.0	COG2010@1|root,COG2010@2|Bacteria,1N8E4@1224|Proteobacteria,2VWFV@28216|Betaproteobacteria,3T4IZ@506|Alcaligenaceae	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7080731_2	392499.Swit_3251	2.041e-56	214.0	28V8Y@1|root,2ZHBX@2|Bacteria,1RD5G@1224|Proteobacteria,2U7RU@28211|Alphaproteobacteria,2K4YJ@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM methylamine dehydrogenase light chain, C terminal domain protein	-	-	1.4.9.1	ko:K15228	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_L
CMS3_k127_7080731_1	1156919.QWC_28473	1.808e-59	216.0	COG0526@1|root,COG0526@2|Bacteria,1R3WA@1224|Proteobacteria,2VQKN@28216|Betaproteobacteria,3T2TU@506|Alcaligenaceae	28216|Betaproteobacteria	CO	Methylamine dehydrogenase accessory protein MauD	mauD	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_2
CMS3_k127_7080731_5	742159.HMPREF0004_2469	1.734e-11	74.0	2DR4K@1|root,33A57@2|Bacteria,1QVJ6@1224|Proteobacteria,2WI2T@28216|Betaproteobacteria,3T4MQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
CMS3_k127_7091689_1	667014.Thein_1717	2.451e-217	711.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GHDG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS3_k127_7091689_30	555079.Toce_1058	1.223e-20	93.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,42H5S@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_7091689_33	1519464.HY22_04875	1.95e-16	92.0	COG1309@1|root,COG1309@2|Bacteria,1FF9F@1090|Chlorobi	1090|Chlorobi	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7091689_19	290397.Adeh_2353	2.981e-44	168.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2Z0GF@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS3_k127_7091689_4	1173021.ALWA01000025_gene2523	2.389e-126	411.0	COG0031@1|root,COG0031@2|Bacteria,1G1AB@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_7091689_13	269799.Gmet_3033	1.469e-64	235.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,43SVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS3_k127_7091689_15	1120973.AQXL01000128_gene2883	4.291e-54	211.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,278C3@186823|Alicyclobacillaceae	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS3_k127_7091689_38	690850.Desaf_2174	3.111e-09	71.0	COG0589@1|root,COG0589@2|Bacteria,1NBKV@1224|Proteobacteria,42X7W@68525|delta/epsilon subdivisions,2WT65@28221|Deltaproteobacteria,2M7X9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_7091689_36	215803.DB30_5440	2.353e-10	68.0	2CIY5@1|root,2ZET1@2|Bacteria,1P8MM@1224|Proteobacteria,4330I@68525|delta/epsilon subdivisions,2WXKY@28221|Deltaproteobacteria,2YW19@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7091689_14	42256.RradSPS_2095	1.873e-62	245.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CR6S@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS3_k127_7091689_29	1343740.M271_44395	3.735e-23	117.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_7091689_34	246196.MSMEI_4761	4.646e-13	80.0	COG2334@1|root,COG2334@2|Bacteria,2GMC3@201174|Actinobacteria,232AM@1762|Mycobacteriaceae	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_7091689_5	1232410.KI421412_gene408	5.905e-123	406.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,43SYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS3_k127_7091689_7	330214.NIDE2743	2.307e-106	377.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,3J0B6@40117|Nitrospirae	40117|Nitrospirae	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CMS3_k127_7091689_12	1120972.AUMH01000003_gene2918	6.236e-69	257.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,278YD@186823|Alicyclobacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS3_k127_7091689_9	1125863.JAFN01000001_gene1123	1.417e-97	346.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_7091689_28	56780.SYN_03385	1.834e-24	114.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,2MQGP@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS3_k127_7091689_24	869210.Marky_2052	4.967e-37	145.0	COG2110@1|root,COG2110@2|Bacteria,1WJ1P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_7091689_10	330214.NIDE4314	5.917e-92	325.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7091689_20	414684.RC1_0829	1.737e-42	177.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2U8QT@28211|Alphaproteobacteria,2JSGE@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS3_k127_7091689_23	1121413.JMKT01000014_gene2489	1.096e-37	145.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MC2A@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_7091689_22	313598.MED152_05425	4.857e-38	162.0	COG0204@1|root,COG0560@1|root,COG2937@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,COG2937@2|Bacteria,4NW8D@976|Bacteroidetes,1I6XY@117743|Flavobacteriia,3VV8T@52959|Polaribacter	976|Bacteroidetes	EI	haloacid dehalogenase-like hydrolase	-	-	2.3.1.51,3.1.3.3	ko:K00655,ko:K15781	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,HAD
CMS3_k127_7091689_8	404380.Gbem_2459	7.222e-99	339.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,43TZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS3_k127_7091689_3	56780.SYN_00551	5.856e-143	479.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MQ74@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
CMS3_k127_7091689_18	443143.GM18_2320	2.931e-44	174.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,43TCT@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS3_k127_7091689_2	1192034.CAP_7535	8.366e-160	510.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_7091689_26	706587.Desti_3718	9.862e-28	132.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS3_k127_7091689_11	204669.Acid345_2208	6.76e-73	261.0	COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS3_k127_7091689_27	1303518.CCALI_00091	2.022e-25	116.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_7091689_25	1267535.KB906767_gene3986	1.784e-28	119.0	COG0720@1|root,COG0720@2|Bacteria,3Y4K2@57723|Acidobacteria,2JJD0@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_7091689_16	639030.JHVA01000001_gene427	4.971e-53	194.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria,2JIJ3@204432|Acidobacteriia	204432|Acidobacteriia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS3_k127_7091689_37	105559.Nwat_3039	1.975e-09	69.0	2AI7D@1|root,33HQ0@2|Bacteria,1P2AB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7091689_32	765869.BDW_14210	2.189e-17	91.0	2E05E@1|root,32VTR@2|Bacteria,1N5CW@1224|Proteobacteria,431HU@68525|delta/epsilon subdivisions,2MTES@213481|Bdellovibrionales,2WWRZ@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7091689_21	404589.Anae109_3714	7.605e-41	155.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_7091689_0	290397.Adeh_3594	7.005e-252	787.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_7091689_17	1121949.AQXT01000002_gene1591	5.434e-51	193.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2TVGA@28211|Alphaproteobacteria,43Y6T@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	attY	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_2,GST_N_3
CMS3_k127_7091689_35	1121447.JONL01000006_gene91	4.338e-11	76.0	COG1807@1|root,COG1807@2|Bacteria,1QQYT@1224|Proteobacteria,435NZ@68525|delta/epsilon subdivisions,2X02E@28221|Deltaproteobacteria,2M9ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7091689_6	1192034.CAP_1396	6.285e-123	401.0	COG1075@1|root,COG1075@2|Bacteria,1NB6J@1224|Proteobacteria,42NSJ@68525|delta/epsilon subdivisions,2WM7M@28221|Deltaproteobacteria,2YWAU@29|Myxococcales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lip	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_7092177_9	1463825.JNXC01000009_gene1513	8.338e-06	49.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4DY0G@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
CMS3_k127_7092177_1	477974.Daud_1638	2.961e-65	241.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CMS3_k127_7092177_8	1121918.ARWE01000001_gene840	3.731e-06	56.0	COG5512@1|root,COG5512@2|Bacteria,1N24G@1224|Proteobacteria,42TXW@68525|delta/epsilon subdivisions,2WQ15@28221|Deltaproteobacteria,43SMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS3_k127_7092177_5	944479.JQLX01000015_gene135	6.785e-20	94.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2M7EP@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS3_k127_7092177_7	324057.Pjdr2_3482	4.685e-08	62.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,26Z1T@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
CMS3_k127_7092177_4	1169161.KB897714_gene6249	1.99e-21	106.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS3_k127_7092177_0	298654.FraEuI1c_1070	8.56e-79	271.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4ERT5@85013|Frankiales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
CMS3_k127_7092177_3	1223542.GM1_012_00980	2.257e-38	150.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4GE3E@85026|Gordoniaceae	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS3_k127_7092177_6	1122239.AULS01000001_gene1753	3.777e-19	98.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4FPTI@85023|Microbacteriaceae	201174|Actinobacteria	L	nucleic acid phosphodiester bond hydrolysis	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS3_k127_7092177_2	246197.MXAN_3552	3.832e-60	216.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2YV9J@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS3_k127_7107868_5	1232410.KI421420_gene3159	5.006e-27	120.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_7107868_4	1232410.KI421428_gene1082	2.249e-52	197.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,43THQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulatory protein IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS3_k127_7107868_0	443143.GM18_3276	4.437e-174	557.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	mdh	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS3_k127_7107868_1	671143.DAMO_1217	1.954e-151	499.0	COG0439@1|root,COG0439@2|Bacteria,2NNKD@2323|unclassified Bacteria	2|Bacteria	I	carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01965,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00373,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_7107868_3	879212.DespoDRAFT_02581	3.69e-58	214.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2MI7G@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS3_k127_7107868_6	555779.Dthio_PD2455	9.2e-15	77.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MDCV@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_7107868_2	477974.Daud_0677	1.951e-60	224.0	COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,264DA@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_7131050_12	765420.OSCT_2002	3.081e-30	137.0	COG1649@1|root,COG1649@2|Bacteria,2G9K4@200795|Chloroflexi	200795|Chloroflexi	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS3_k127_7131050_10	404589.Anae109_1953	3.432e-53	214.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2YV6T@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_19,TPR_6,TPR_8
CMS3_k127_7131050_17	290397.Adeh_0902	1.639e-10	72.0	28S5K@1|root,2ZEH5@2|Bacteria	2|Bacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
CMS3_k127_7131050_4	880073.Calab_2578	5.43e-112	379.0	COG4284@1|root,COG4284@2|Bacteria	2|Bacteria	G	Utp--glucose-1-phosphate uridylyltransferase	CP_1013	-	2.7.7.23,2.7.7.83	ko:K00972,ko:K11442	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS3_k127_7131050_18	1297742.A176_05979	0.0001107	55.0	COG0457@1|root,COG3118@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	hupG	-	-	ko:K03619,ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	BCSC_C,HyaE,TPR_16,TPR_19,TPR_8
CMS3_k127_7131050_3	760568.Desku_1838	3.697e-118	396.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS3_k127_7131050_7	439235.Dalk_4638	5.811e-70	267.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MIV4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS3_k127_7131050_2	1385517.N800_12875	6.943e-126	424.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1X4XY@135614|Xanthomonadales	135614|Xanthomonadales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS3_k127_7131050_11	472759.Nhal_2229	3.644e-42	168.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WW4B@135613|Chromatiales	135613|Chromatiales	T	response regulator	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Sigma54_activat
CMS3_k127_7131050_6	404589.Anae109_3696	2.87e-80	275.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42T24@68525|delta/epsilon subdivisions,2WPF8@28221|Deltaproteobacteria,2YV09@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS3_k127_7131050_16	1144275.COCOR_02019	1.311e-10	74.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,431UR@68525|delta/epsilon subdivisions,2WWZQ@28221|Deltaproteobacteria,2YU65@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
CMS3_k127_7131050_15	595460.RRSWK_05226	1.713e-12	70.0	2EGPU@1|root,32K36@2|Bacteria,2J1G1@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7131050_14	886293.Sinac_7434	4.377e-13	75.0	2BR4A@1|root,32K29@2|Bacteria,2J1BQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7131050_0	344747.PM8797T_18941	3.293e-257	812.0	COG2192@1|root,COG2192@2|Bacteria,2IYCS@203682|Planctomycetes	203682|Planctomycetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_7131050_8	1240349.ANGC01000031_gene3062	6.538e-62	230.0	COG1482@1|root,COG1482@2|Bacteria,2GJXC@201174|Actinobacteria,4G6IP@85025|Nocardiaceae	201174|Actinobacteria	G	Phosphomannose isomerase type I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS3_k127_7131050_1	627192.SLG_15950	1.452e-165	525.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,2K1V1@204457|Sphingomonadales	204457|Sphingomonadales	GM	GDP-mannose 4,6 dehydratase	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd,Glyco_trans_1_2
CMS3_k127_7131050_5	391625.PPSIR1_10520	1.222e-93	313.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
CMS3_k127_7131050_9	640081.Dsui_3446	1.593e-54	201.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,2KX0U@206389|Rhodocyclales	206389|Rhodocyclales	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS3_k127_7131050_13	1125863.JAFN01000001_gene229	1.069e-21	97.0	2EH48@1|root,33AW7@2|Bacteria,1NIYU@1224|Proteobacteria,42XKK@68525|delta/epsilon subdivisions,2WSKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142059_0	469371.Tbis_1838	5.019e-197	643.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4DZ1H@85010|Pseudonocardiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
CMS3_k127_7142059_19	1340493.JNIF01000003_gene3336	3.848e-27	124.0	COG3595@1|root,COG3595@2|Bacteria,3Y5MS@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_7142059_15	290318.Cvib_1767	2.053e-37	155.0	COG0705@1|root,COG0705@2|Bacteria,1FDF1@1090|Chlorobi	1090|Chlorobi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_7142059_14	1121405.dsmv_2237	7.793e-42	164.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42W8P@68525|delta/epsilon subdivisions,2WRV4@28221|Deltaproteobacteria,2MKN4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_7142059_18	1125863.JAFN01000001_gene888	2.345e-27	119.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,42TXX@68525|delta/epsilon subdivisions,2WQBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4,Peptidase_S15
CMS3_k127_7142059_9	443598.AUFA01000001_gene997	1.628e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria,3JQUD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Dehydrogenase	MA20_18560	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_7142059_22	1198232.CYCME_2024	7.935e-12	78.0	2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
CMS3_k127_7142059_12	1335760.ASTG01000017_gene3465	2.145e-47	196.0	2E40H@1|root,32YXB@2|Bacteria,1NE9K@1224|Proteobacteria,2UH9T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_7142059_11	1175306.GWL_31020	2.038e-52	214.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,476K9@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PAS fold	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9
CMS3_k127_7142059_20	1380356.JNIK01000013_gene4137	7.886e-24	109.0	2CJXB@1|root,2ZIFC@2|Bacteria,2H9YF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142059_4	1110502.TMO_2732	2.662e-129	439.0	COG2159@1|root,COG2159@2|Bacteria,1R7D7@1224|Proteobacteria	1224|Proteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_7142059_8	1206744.BAGL01000064_gene4514	7.915e-75	282.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria,4FYFT@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_7142059_3	1313172.YM304_18860	2.353e-154	496.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_7142059_2	1123242.JH636435_gene1110	4.076e-163	527.0	COG1252@1|root,COG1252@2|Bacteria,2IXBA@203682|Planctomycetes	203682|Planctomycetes	C	NADH dehydrogenase, FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_7142059_10	1240350.AMZE01000035_gene2177	2.939e-58	228.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1YV8G@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Sulfatase	mdoB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006490,GO:0006629,GO:0008150,GO:0008152,GO:0008960,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0042597,GO:0044237,GO:0044238,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_7142059_13	1499967.BAYZ01000125_gene2598	1.503e-44	189.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
CMS3_k127_7142059_17	452637.Oter_2407	1.394e-31	139.0	COG4191@1|root,COG4191@2|Bacteria,46W3V@74201|Verrucomicrobia,3K9SN@414999|Opitutae	414999|Opitutae	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS3_k127_7142059_1	96561.Dole_2534	4.177e-191	628.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
CMS3_k127_7142059_7	1123072.AUDH01000011_gene3607	8.033e-88	303.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,2JPV4@204441|Rhodospirillales	204441|Rhodospirillales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CMS3_k127_7142059_5	880073.Calab_0859	1.532e-128	467.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714,ko:K19641	ko02020,map02020	M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_7142059_21	1168034.FH5T_19890	2.665e-19	101.0	2DN8B@1|root,32W2U@2|Bacteria,4P2T3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142059_6	1033802.SSPSH_000544	1.629e-88	316.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hydrolase of alkaline phosphatase superfamily	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
CMS3_k127_7142059_25	1370122.JHXQ01000007_gene3192	2.785e-05	54.0	COG2365@1|root,COG2365@2|Bacteria,1RJ2P@1224|Proteobacteria,2UB4E@28211|Alphaproteobacteria,4BEN0@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Protein tyrosine serine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
CMS3_k127_7142059_16	1501230.ET33_05670	2.537e-37	155.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,26XF4@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778,ko:K13531	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS3_k127_7142899_12	207954.MED92_08361	2.118e-125	420.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XIA2@135619|Oceanospirillales	135619|Oceanospirillales	Q	Paraquat-inducible protein B	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
CMS3_k127_7142899_26	1283284.AZUK01000001_gene1167	9.265e-60	214.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1Y3WR@135624|Aeromonadales	135624|Aeromonadales	S	paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
CMS3_k127_7142899_39	207954.MED92_08366	2.188e-38	152.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1XIA3@135619|Oceanospirillales	135619|Oceanospirillales	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
CMS3_k127_7142899_2	1167006.UWK_00955	5.555e-282	897.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,42NVF@68525|delta/epsilon subdivisions,2WKNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Fatty acid cis/trans isomerase (CTI)	-	-	-	-	-	-	-	-	-	-	-	-	CTI
CMS3_k127_7142899_20	251229.Chro_4001	2.225e-77	273.0	COG0625@1|root,COG0625@2|Bacteria,1G34I@1117|Cyanobacteria,3VHY7@52604|Pleurocapsales	1117|Cyanobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
CMS3_k127_7142899_33	349521.HCH_00674	1.23e-49	201.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1XJM9@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9
CMS3_k127_7142899_45	1121937.AUHJ01000017_gene3028	1.833e-23	105.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_7142899_40	1229780.BN381_290028	4.832e-37	151.0	28KNT@1|root,2ZA6Z@2|Bacteria,2GNXC@201174|Actinobacteria	201174|Actinobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
CMS3_k127_7142899_7	875328.JDM601_0083	1.274e-148	484.0	COG1073@1|root,COG1073@2|Bacteria,2H0FD@201174|Actinobacteria,232Y8@1762|Mycobacteriaceae	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142899_41	247633.GP2143_08925	1.161e-34	141.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1J6UJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818	-	-	-	-	-	-	-	-	-	-	DUF1289,NUDIX
CMS3_k127_7142899_22	745014.OMB55_00024990	1.363e-72	256.0	COG3917@1|root,COG3917@2|Bacteria,1R3XW@1224|Proteobacteria,1SSU7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_7142899_47	745014.OMB55_00024990	1.453e-19	102.0	COG3917@1|root,COG3917@2|Bacteria,1R3XW@1224|Proteobacteria,1SSU7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_7142899_27	391625.PPSIR1_02286	3.425e-58	228.0	COG1404@1|root,COG1404@2|Bacteria,1PFN6@1224|Proteobacteria,43A1H@68525|delta/epsilon subdivisions,2X26T@28221|Deltaproteobacteria,2Z2JW@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_7142899_18	479433.Caci_3609	3.517e-87	299.0	COG2227@1|root,COG2227@2|Bacteria,2I8GJ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_7142899_1	357808.RoseRS_2714	4.025e-288	929.0	COG3250@1|root,COG3250@2|Bacteria,2G61D@200795|Chloroflexi,377DI@32061|Chloroflexia	32061|Chloroflexia	G	glycoside hydrolase family 2, immunoglobulin domain protein beta-sandwich	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS3_k127_7142899_56	384765.SIAM614_19711	4.421e-05	56.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7142899_37	1267535.KB906767_gene5001	4.806e-44	182.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_7142899_52	351160.LRC591	3.591e-11	69.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
CMS3_k127_7142899_16	1078020.KEK_09262	4.413e-91	334.0	COG3173@1|root,COG3173@2|Bacteria,2IEPN@201174|Actinobacteria,233FS@1762|Mycobacteriaceae	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_7142899_3	383372.Rcas_0919	1.052e-246	791.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
CMS3_k127_7142899_43	861299.J421_1956	1.011e-29	138.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_7142899_24	502025.Hoch_1867	1.195e-69	255.0	COG4638@1|root,COG4638@2|Bacteria,1MXXI@1224|Proteobacteria,439H5@68525|delta/epsilon subdivisions,2X4TA@28221|Deltaproteobacteria,2YZJH@29|Myxococcales	28221|Deltaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_7142899_49	985054.JQEZ01000003_gene1516	3.554e-16	85.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7142899_15	1333998.M2A_2721	1.159e-101	346.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TRWW@28211|Alphaproteobacteria,4BR2E@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_7142899_5	402881.Plav_2990	6.774e-167	531.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,1JNEK@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_7142899_36	1122194.AUHU01000004_gene1502	1.021e-44	169.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,467KT@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
CMS3_k127_7142899_31	1123258.AQXZ01000018_gene895	2.481e-51	207.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	naoX	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_7142899_0	1123258.AQXZ01000018_gene894	7.373e-315	1018.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4G1CI@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS3_k127_7142899_13	402881.Plav_2411	1.666e-113	379.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2U14P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_7142899_55	1415166.NONO_c69270	1.984e-05	53.0	COG3832@1|root,COG3832@2|Bacteria,2IJSJ@201174|Actinobacteria,4G0QJ@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_7142899_9	575540.Isop_2691	2.156e-137	451.0	COG0172@1|root,COG0172@2|Bacteria,2IXGP@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS3_k127_7142899_10	1242864.D187_002023	1.425e-134	453.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
CMS3_k127_7142899_35	114615.BRADO2238	1.73e-45	179.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Lipase_GDSL_2
CMS3_k127_7142899_46	596151.DesfrDRAFT_2898	2.628e-21	109.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_7142899_21	1122132.AQYH01000010_gene4009	1.034e-72	271.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_7142899_25	518766.Rmar_1251	3.146e-60	238.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1FJ04@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_7142899_14	1125863.JAFN01000001_gene2409	4.883e-105	383.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS3_k127_7142899_19	1379270.AUXF01000003_gene3533	6.024e-83	305.0	COG1009@1|root,COG1009@2|Bacteria,1ZUA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS3_k127_7142899_53	1068980.ARVW01000001_gene2636	2.904e-10	67.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4E4HB@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS3_k127_7142899_50	1121468.AUBR01000027_gene2907	3.197e-13	72.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,25N8R@186801|Clostridia,42HC4@68295|Thermoanaerobacterales	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS3_k127_7142899_4	1157943.KB892705_gene3119	2.761e-183	599.0	COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria,235FD@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ferrous iron transport protein B C terminus	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
CMS3_k127_7142899_58	671143.DAMO_0225	0.0004786	53.0	COG0457@1|root,COG0457@2|Bacteria	671143.DAMO_0225|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142899_34	439235.Dalk_0190	1.812e-47	191.0	COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_7142899_38	55529.EKX49057	6.116e-43	171.0	COG0637@1|root,KOG2914@2759|Eukaryota	2759|Eukaryota	L	pseudouridine 5'-phosphatase activity	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066	-	-	-	-	-	-	-	-	-	-	HAD_2,NHL,Thioredoxin_8
CMS3_k127_7142899_28	502025.Hoch_5232	6.348e-57	207.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria,2YV4M@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS3_k127_7142899_8	66875.JODY01000006_gene2209	2.495e-140	460.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_7142899_23	1121937.AUHJ01000001_gene354	4e-70	246.0	COG0625@1|root,COG0625@2|Bacteria,1RHXQ@1224|Proteobacteria,1S6QZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	glutathione transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142899_57	679926.Mpet_0132	0.0001283	55.0	arCOG03264@1|root,arCOG06661@1|root,arCOG03264@2157|Archaea,arCOG06661@2157|Archaea	2157|Archaea	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Glucodextran_C,PEGA
CMS3_k127_7142899_30	344747.PM8797T_19096	4.038e-54	205.0	COG0811@1|root,COG0811@2|Bacteria,2J0K4@203682|Planctomycetes	203682|Planctomycetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
CMS3_k127_7142899_48	344747.PM8797T_19101	1.672e-16	89.0	2ENWP@1|root,33GHM@2|Bacteria,2J3DB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142899_44	344747.PM8797T_12398	2.333e-25	122.0	2EEMD@1|root,338FA@2|Bacteria,2J2UH@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7142899_32	1463820.JOGW01000012_gene4029	1.524e-50	198.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	bar	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
CMS3_k127_7142899_17	378806.STAUR_1936	2.694e-88	300.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2YUHQ@29|Myxococcales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS3_k127_7142899_29	1123242.JH636436_gene594	2.86e-56	203.0	COG1611@1|root,COG1611@2|Bacteria,2IZK9@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS3_k127_7142899_11	765420.OSCT_2601	1.291e-133	443.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,376G2@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_7142899_42	1313172.YM304_01220	3.895e-33	147.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_7142899_6	247634.GPB2148_3615	1.676e-159	515.0	COG5285@1|root,COG5285@2|Bacteria,1NXM8@1224|Proteobacteria	1224|Proteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_7142899_51	591167.Sfla_6015	1.017e-11	78.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the peptidase S33 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_7178996_1	1123256.KB907939_gene239	1.045e-34	146.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1X4PF@135614|Xanthomonadales	135614|Xanthomonadales	I	fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_7178996_0	203119.Cthe_1007	1.484e-209	670.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_7178996_2	479435.Kfla_5740	2.223e-34	142.0	COG5285@1|root,COG5285@2|Bacteria,2GP1T@201174|Actinobacteria,4DWBH@85009|Propionibacteriales	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	ectD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_7192581_6	1122992.CBQQ010000046_gene290	2.042e-34	134.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,2FPMW@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_7192581_8	1348114.OM33_12440	3.382e-23	107.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,2Q245@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS3_k127_7192581_2	215803.DB30_3499	3.205e-142	466.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS3_k127_7192581_1	1125863.JAFN01000001_gene1429	2.237e-200	651.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS3_k127_7192581_10	1521187.JPIM01000051_gene3486	8.032e-13	83.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi,375YB@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
CMS3_k127_7192581_9	1266909.AUAG01000007_gene2368	8.801e-16	87.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales	135613|Chromatiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS3_k127_7192581_3	338966.Ppro_0966	1.658e-69	254.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,43UI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
CMS3_k127_7192581_7	138119.DSY2512	6.633e-28	116.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,262DU@186807|Peptococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS3_k127_7192581_0	1125863.JAFN01000001_gene1435	1.055e-224	719.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS3_k127_7192581_4	1207063.P24_14844	4.366e-54	197.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2JS8T@204441|Rhodospirillales	204441|Rhodospirillales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS3_k127_7192581_5	1128421.JAGA01000003_gene3286	1.645e-39	160.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS3_k127_7207260_3	1229780.BN381_360022	3.82e-71	256.0	COG1680@1|root,COG1680@2|Bacteria,2HEWU@201174|Actinobacteria,3UXIA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_7207260_9	177437.HRM2_22240	2.609e-29	129.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS3_k127_7207260_1	101510.RHA1_ro11036	3.316e-74	258.0	COG1028@1|root,COG1028@2|Bacteria,2GIRG@201174|Actinobacteria,4FU04@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_7207260_6	1122247.C731_4887	6.699e-47	180.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,237DT@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_7207260_8	1229205.BUPH_05353	1.133e-32	136.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,1K8PZ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Regulatory protein ArsR	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
CMS3_k127_7207260_7	118173.KB235914_gene1320	2.165e-34	137.0	COG0346@1|root,COG0346@2|Bacteria,1G9V2@1117|Cyanobacteria,1HHKS@1150|Oscillatoriales	1117|Cyanobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_7207260_11	1469245.JFBG01000026_gene1565	1e-28	122.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,1WYP7@135613|Chromatiales	135613|Chromatiales	S	PFAM glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_7207260_0	388467.A19Y_0621	4.204e-130	454.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1H9BT@1150|Oscillatoriales	1117|Cyanobacteria	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_7207260_10	497964.CfE428DRAFT_4096	5.607e-29	134.0	2D25X@1|root,32TC5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7207260_5	102129.Lepto7375DRAFT_7025	3.255e-47	184.0	28JAJ@1|root,2Z95C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7207260_12	1169161.KB897722_gene4379	1.397e-24	115.0	COG2207@1|root,COG2207@2|Bacteria,2GWDZ@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_7207260_4	1125863.JAFN01000001_gene921	1.331e-65	256.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS3_k127_7207260_2	1415780.JPOG01000001_gene1948	8.071e-74	260.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1X9CN@135614|Xanthomonadales	135614|Xanthomonadales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,APH
CMS3_k127_7209862_22	485915.Dret_1182	3.297e-12	74.0	2C678@1|root,32D7Q@2|Bacteria,1P0IC@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7209862_8	1266909.AUAG01000003_gene774	4.88e-81	284.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	-	-	3.2.1.183	ko:K08068	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
CMS3_k127_7209862_21	1227487.C474_09167	1.81e-18	99.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_7209862_1	1205680.CAKO01000029_gene5218	7.984e-205	647.0	COG2141@1|root,COG2141@2|Bacteria,1R7GC@1224|Proteobacteria,2U0DW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_7209862_9	402881.Plav_0572	2.543e-70	265.0	COG0596@1|root,COG0596@2|Bacteria,1PFTV@1224|Proteobacteria,2V8R3@28211|Alphaproteobacteria,1JQG3@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7209862_2	1297742.A176_04402	1.679e-174	579.0	COG2133@1|root,COG2133@2|Bacteria,1PER7@1224|Proteobacteria,4399G@68525|delta/epsilon subdivisions,2X4GV@28221|Deltaproteobacteria,2YYZS@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_7209862_6	1254432.SCE1572_48085	1.432e-109	389.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria	1224|Proteobacteria	H	biosynthesis protein E	pqqE	GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_7209862_10	272568.GDI1269	2.286e-64	253.0	COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,2TSQT@28211|Alphaproteobacteria,2JRFA@204441|Rhodospirillales	204441|Rhodospirillales	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
CMS3_k127_7209862_12	1166948.JPZL01000002_gene1137	6.478e-60	218.0	COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,1RMM9@1236|Gammaproteobacteria,1XH54@135619|Oceanospirillales	135619|Oceanospirillales	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
CMS3_k127_7209862_0	1238182.C882_1194	0.0	1297.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,2JPW3@204441|Rhodospirillales	204441|Rhodospirillales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS3_k127_7209862_15	1123073.KB899241_gene3120	2.82e-52	214.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1X3ZV@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_7209862_16	290397.Adeh_0162	3.678e-50	203.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2WM6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
CMS3_k127_7209862_14	479434.Sthe_3375	2.098e-54	208.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi,27YUW@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS3_k127_7209862_13	1530186.JQEY01000001_gene765	2.079e-55	209.0	COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,2TTTJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_7209862_23	1128421.JAGA01000002_gene1599	9.703e-12	78.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7209862_11	269799.Gmet_0585	3.545e-61	228.0	COG0859@1|root,COG0859@2|Bacteria,1PQIG@1224|Proteobacteria,42MUM@68525|delta/epsilon subdivisions,2WPZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CMS3_k127_7209862_4	1499967.BAYZ01000090_gene4943	2.611e-118	413.0	COG0535@1|root,COG0535@2|Bacteria,2NPKA@2323|unclassified Bacteria	2|Bacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_7209862_20	643562.Daes_0701	1.07e-18	100.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_7209862_19	1123072.AUDH01000014_gene1296	5.429e-24	119.0	COG2227@1|root,COG2227@2|Bacteria,1RI5H@1224|Proteobacteria,2U966@28211|Alphaproteobacteria,2JUN7@204441|Rhodospirillales	204441|Rhodospirillales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_7209862_7	1219035.NT2_08_00810	2.284e-93	334.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,2K368@204457|Sphingomonadales	204457|Sphingomonadales	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
CMS3_k127_7209862_5	1192034.CAP_4624	5.102e-117	387.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PVS@68525|delta/epsilon subdivisions,2WJ7B@28221|Deltaproteobacteria,2YXQQ@29|Myxococcales	28221|Deltaproteobacteria	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
CMS3_k127_7209862_3	1266925.JHVX01000007_gene2381	5.082e-144	506.0	COG0841@1|root,COG0841@2|Bacteria,1QWAZ@1224|Proteobacteria,2WGXK@28216|Betaproteobacteria,372WP@32003|Nitrosomonadales	28216|Betaproteobacteria	V	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_7209862_18	7237.FBpp0297965	2.864e-31	140.0	COG0666@1|root,KOG4369@1|root,KOG0504@2759|Eukaryota,KOG4369@2759|Eukaryota,38I05@33154|Opisthokonta,3BHRH@33208|Metazoa,3CU4I@33213|Bilateria,41XRM@6656|Arthropoda,3SIQV@50557|Insecta,4517H@7147|Diptera,45NAG@7214|Drosophilidae	33208|Metazoa	T	RNA binding	ANKRD17	GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112	-	ko:K16726	-	-	-	-	ko00000,ko03036	-	-	-	Ank_2,Ank_4,KH_1
CMS3_k127_7213721_54	797114.C475_12537	1.23e-22	113.0	COG3119@1|root,arCOG02785@2157|Archaea,2XV54@28890|Euryarchaeota,23UWR@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_7213721_30	1185876.BN8_01274	1.035e-60	229.0	COG3751@1|root,COG3751@2|Bacteria,4NI8F@976|Bacteroidetes,47QQK@768503|Cytophagia	976|Bacteroidetes	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
CMS3_k127_7213721_25	269799.Gmet_1239	1.973e-78	274.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,42M13@68525|delta/epsilon subdivisions,2WQAC@28221|Deltaproteobacteria,43T6M@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
CMS3_k127_7213721_50	926554.KI912633_gene3866	8.2e-24	118.0	COG2267@1|root,COG2267@2|Bacteria,1WIH1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
CMS3_k127_7213721_44	319225.Plut_0230	7.601e-37	145.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3,AhpC-TSA
CMS3_k127_7213721_43	1125863.JAFN01000001_gene3376	1.24e-40	158.0	COG1051@1|root,COG1051@2|Bacteria,1RJAP@1224|Proteobacteria,42SFP@68525|delta/epsilon subdivisions,2WPBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_7213721_47	290397.Adeh_1251	1.11e-28	131.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2Z0ZJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7213721_46	101510.RHA1_ro05140	3.74e-29	128.0	COG2267@1|root,COG2267@2|Bacteria,2I94I@201174|Actinobacteria,4FYKH@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_7213721_23	518766.Rmar_2205	1.072e-83	297.0	COG0154@1|root,COG0154@2|Bacteria,4PIBP@976|Bacteroidetes,1FK1Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_7213721_21	448385.sce2044	9.14e-90	306.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_7213721_31	998674.ATTE01000001_gene3400	1.161e-59	219.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS3_k127_7213721_10	247633.GP2143_01765	8.624e-136	476.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,1RQYQ@1236|Gammaproteobacteria,1J5B4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_7213721_29	1175306.GWL_31020	3.627e-61	239.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,476K9@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PAS fold	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9
CMS3_k127_7213721_12	1463936.JOJI01000012_gene6281	7.268e-129	446.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_7213721_42	283942.IL2442	6.089e-42	172.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,2QGJQ@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	MgtC family	mgtC	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_7213721_36	2074.JNYD01000005_gene3220	1.233e-50	189.0	2BVHN@1|root,332R2@2|Bacteria,2IPM7@201174|Actinobacteria,4EBJ7@85010|Pseudonocardiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_7213721_55	1123277.KB893201_gene6427	1.308e-22	109.0	2DFZW@1|root,2ZTW5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7213721_27	614083.AWQR01000030_gene2784	1.244e-63	222.0	COG1720@1|root,COG1720@2|Bacteria	2|Bacteria	S	tRNA m6t6A37 methyltransferase activity	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,UPF0066
CMS3_k127_7213721_53	1117318.PRUB_15595	7.045e-23	105.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,1S5RX@1236|Gammaproteobacteria,2Q31F@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CMS3_k127_7213721_40	1380358.JADJ01000003_gene4593	1.809e-45	173.0	COG3911@1|root,COG3911@2|Bacteria,1RD7P@1224|Proteobacteria,1S3SW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CMS3_k127_7213721_48	350054.Mflv_4472	3.51e-27	114.0	COG3631@1|root,COG3631@2|Bacteria,2IM62@201174|Actinobacteria,23A0F@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_7213721_11	1030157.AFMP01000026_gene1009	2.376e-131	434.0	28JDP@1|root,2Z97Z@2|Bacteria,1R6U7@1224|Proteobacteria,2UIH3@28211|Alphaproteobacteria,2K72A@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7213721_22	443218.AS9A_4297	3.568e-84	295.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,233DK@1762|Mycobacteriaceae	201174|Actinobacteria	C	cytochrome p450	cyp123A3	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_7213721_34	8153.XP_005934294.1	1.188e-55	207.0	COG3186@1|root,KOG3820@2759|Eukaryota,38G6R@33154|Opisthokonta,3BB8B@33208|Metazoa,3CUNE@33213|Bilateria,486X3@7711|Chordata,492HH@7742|Vertebrata,4A2E0@7898|Actinopterygii	33208|Metazoa	E	Phenylalanine hydroxylase	PAH	GO:0000003,GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0004510,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006464,GO:0006520,GO:0006558,GO:0006559,GO:0006568,GO:0006569,GO:0006570,GO:0006571,GO:0006576,GO:0006582,GO:0006584,GO:0006586,GO:0006725,GO:0006726,GO:0006732,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008150,GO:0008152,GO:0008340,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009073,GO:0009074,GO:0009095,GO:0009308,GO:0009310,GO:0009712,GO:0009713,GO:0009987,GO:0010259,GO:0016053,GO:0016054,GO:0016491,GO:0016597,GO:0016705,GO:0016714,GO:0017144,GO:0018126,GO:0018958,GO:0019438,GO:0019439,GO:0019538,GO:0019748,GO:0019751,GO:0019752,GO:0031406,GO:0032501,GO:0032502,GO:0034311,GO:0034641,GO:0036094,GO:0036211,GO:0040002,GO:0042133,GO:0042136,GO:0042335,GO:0042402,GO:0042423,GO:0042430,GO:0042436,GO:0042438,GO:0042440,GO:0042441,GO:0042558,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043324,GO:0043412,GO:0043436,GO:0043473,GO:0043474,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046146,GO:0046148,GO:0046189,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0048066,GO:0048069,GO:0048856,GO:0050877,GO:0050890,GO:0050896,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901615,GO:1901617,GO:1902221,GO:1902222	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	ACT,Biopterin_H
CMS3_k127_7213721_33	1458427.BAWN01000032_gene1794	9.569e-59	212.0	COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,2VTPN@28216|Betaproteobacteria,4AEPX@80864|Comamonadaceae	28216|Betaproteobacteria	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_7213721_39	1077144.AGFF01000005_gene2255	5.835e-47	173.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_7213721_8	448385.sce5541	2.563e-152	503.0	2CB1C@1|root,2Z7M2@2|Bacteria,1Q9R6@1224|Proteobacteria,438X5@68525|delta/epsilon subdivisions,2X42J@28221|Deltaproteobacteria,2YY36@29|Myxococcales	28221|Deltaproteobacteria	S	Transmembrane protein of unknown function (DUF3556)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3556
CMS3_k127_7213721_5	1123508.JH636444_gene5358	4.407e-169	572.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_7213721_1	1229780.BN381_290049	1.968e-234	743.0	COG2015@1|root,COG2015@2|Bacteria,2GK38@201174|Actinobacteria	201174|Actinobacteria	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
CMS3_k127_7213721_38	557599.MKAN_23405	1.015e-48	185.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
CMS3_k127_7213721_0	1313172.YM304_20880	2.148e-279	871.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	pamO	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576	1.14.13.170,1.14.13.171,1.14.13.22	ko:K03379,ko:K18091	ko00930,ko01120,ko01130,ko01220,map00930,map01120,map01130,map01220	M00819	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko00002,ko01000	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
CMS3_k127_7213721_3	1211815.CBYP010000068_gene194	2.348e-190	611.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_7213721_18	1123279.ATUS01000001_gene1109	7.088e-101	340.0	COG1024@1|root,COG1024@2|Bacteria,1R3Q4@1224|Proteobacteria,1RQ45@1236|Gammaproteobacteria,1J5CQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_7213721_9	247633.GP2143_09795	9.538e-140	468.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS3_k127_7213721_7	247633.GP2143_09790	7.102e-157	541.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_7213721_14	1313172.YM304_15050	1.92e-108	359.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CMS3_k127_7213721_16	1297742.A176_00227	3.922e-103	349.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_7213721_20	1123023.JIAI01000009_gene968	7.704e-93	334.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	htxA	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_7213721_4	1313172.YM304_01060	9.662e-185	610.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_7213721_17	745014.OMB55_00020490	4.472e-101	354.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_7213721_24	247633.GP2143_13961	3.082e-81	277.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RPSX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_7213721_19	1479237.JMLY01000001_gene2098	2.364e-94	327.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,465FA@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_7213721_37	1112204.GPOL_c00690	4.342e-50	193.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,4GDHU@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_7213721_49	1288494.EBAPG3_3000	4.945e-25	115.0	2EFX2@1|root,339PA@2|Bacteria,1NGKD@1224|Proteobacteria,2VY14@28216|Betaproteobacteria,374HM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS3_k127_7213721_41	1144275.COCOR_05286	9.477e-43	177.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BWI@68525|delta/epsilon subdivisions,2X77B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS3_k127_7213721_15	1278073.MYSTI_05613	4.189e-105	377.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria,2Z3FM@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_7213721_57	1122239.AULS01000001_gene1883	5.158e-11	71.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_14935	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7213721_28	1120936.KB907208_gene1207	2.157e-62	233.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7213721_26	983917.RGE_22550	1.606e-72	273.0	COG0421@1|root,COG0421@2|Bacteria,1QY0T@1224|Proteobacteria,2WH8S@28216|Betaproteobacteria,1KMY8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_7213721_35	349124.Hhal_0101	8.827e-51	187.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WXZK@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_7213721_13	1128421.JAGA01000003_gene2905	1.844e-124	417.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
CMS3_k127_7213721_2	237368.SCABRO_03724	3.197e-192	621.0	COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
CMS3_k127_7213721_6	237368.SCABRO_03725	8.17e-161	517.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
CMS3_k127_7213721_32	1333998.M2A_1974	2.45e-59	219.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,4BQU9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_7213721_56	96561.Dole_2261	4.057e-17	94.0	COG0607@1|root,COG1633@1|root,COG0607@2|Bacteria,COG1633@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2MJ8M@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
CMS3_k127_7213721_52	880072.Desac_2775	2.322e-23	106.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ88@28221|Deltaproteobacteria,2MS3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_7213721_51	96561.Dole_2642	1.151e-23	111.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MKAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_7213721_45	879212.DespoDRAFT_00177	2.753e-33	138.0	COG0484@1|root,COG0484@2|Bacteria,1N19U@1224|Proteobacteria,42TX7@68525|delta/epsilon subdivisions,2WQMA@28221|Deltaproteobacteria,2MNA8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
CMS3_k127_7213721_59	930169.B5T_01814	3.718e-07	62.0	COG0695@1|root,COG0695@2|Bacteria,1NH8Z@1224|Proteobacteria,1SGAT@1236|Gammaproteobacteria,1XMKE@135619|Oceanospirillales	135619|Oceanospirillales	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
CMS3_k127_7293222_5	1122247.C731_0704	2.089e-11	68.0	COG2146@1|root,COG2146@2|Bacteria,2IQN9@201174|Actinobacteria,23B0R@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	Rieske
CMS3_k127_7293222_3	1121403.AUCV01000020_gene3106	5.131e-28	127.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS3_k127_7293222_4	269799.Gmet_0390	2.668e-19	93.0	COG0140@1|root,COG0140@2|Bacteria,1QXPJ@1224|Proteobacteria,42S79@68525|delta/epsilon subdivisions,2X7FP@28221|Deltaproteobacteria,43SI3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	phosphoribosyl-ATP diphosphatase activity	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
CMS3_k127_7293222_1	595460.RRSWK_01802	2.513e-58	231.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS3_k127_7293222_0	1123518.ARWI01000001_gene1948	5.89e-243	762.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_7293222_2	713587.THITH_12270	3.646e-47	175.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1SHRA@1236|Gammaproteobacteria,1X25E@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
CMS3_k127_7293620_1	204669.Acid345_1477	2.441e-42	167.0	COG0583@1|root,COG0583@2|Bacteria,3Y4EH@57723|Acidobacteria,2JJ60@204432|Acidobacteriia	204432|Acidobacteriia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_7293620_6	290397.Adeh_1425	0.0001057	49.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS3_k127_7293620_0	926550.CLDAP_22560	3.048e-116	389.0	COG0534@1|root,COG0534@2|Bacteria,2G78S@200795|Chloroflexi	200795|Chloroflexi	V	PFAM multi antimicrobial extrusion protein MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_7293620_3	228410.NE0622	4.987e-28	117.0	COG0662@1|root,COG0662@2|Bacteria,1RFTK@1224|Proteobacteria,2WG1F@28216|Betaproteobacteria,374QB@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_7293620_5	1286106.MPL1_07752	1.681e-07	63.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,1S60V@1236|Gammaproteobacteria,46145@72273|Thiotrichales	72273|Thiotrichales	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_7293620_2	1123072.AUDH01000001_gene2761	1.648e-30	128.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7293620_4	285535.JOEY01000057_gene6481	9.444e-20	90.0	COG0104@1|root,COG0104@2|Bacteria,2IERH@201174|Actinobacteria	201174|Actinobacteria	F	Adenylosuccinate synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Adenylsucc_synt
CMS3_k127_7306599_13	765952.PUV_20760	8.179e-51	191.0	COG3694@1|root,COG3694@2|Bacteria,2JHF2@204428|Chlamydiae	204428|Chlamydiae	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_7306599_16	765952.PUV_20770	4.111e-39	167.0	COG4587@1|root,COG4587@2|Bacteria,2JHFJ@204428|Chlamydiae	204428|Chlamydiae	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
CMS3_k127_7306599_5	1268072.PSAB_07825	9.286e-100	347.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_7306599_10	1229780.BN381_40021	4.07e-69	246.0	COG0778@1|root,COG0778@2|Bacteria,2HG58@201174|Actinobacteria,3UXQT@52018|unclassified Actinobacteria (class)	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_7306599_12	595460.RRSWK_05352	3.704e-51	201.0	COG0515@1|root,COG0515@2|Bacteria,2J2D5@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7306599_11	595460.RRSWK_04882	8.515e-53	197.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_7306599_14	67267.JNXT01000011_gene975	2.452e-49	183.0	COG0526@1|root,COG0526@2|Bacteria,2HZTZ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_7306599_17	1313172.YM304_35760	2.924e-26	115.0	COG0526@1|root,COG0526@2|Bacteria,2HA4Q@201174|Actinobacteria	201174|Actinobacteria	CO	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7306599_2	1313172.YM304_35190	6.809e-198	633.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_7306599_15	469371.Tbis_3474	2.872e-44	170.0	COG1024@1|root,COG1024@2|Bacteria,2I9VC@201174|Actinobacteria,4DX6Z@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Enoyl-CoA hydratase isomerase	echA3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_7306599_4	234267.Acid_6396	1.011e-124	409.0	COG0016@1|root,COG0016@2|Bacteria,3Y3NJ@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS3_k127_7306599_3	1380763.BG53_02755	9.748e-131	458.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,26SV7@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS3_k127_7306599_8	526225.Gobs_2081	2.77e-85	291.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS3_k127_7306599_0	247639.MGP2080_11168	6.474e-255	848.0	COG0439@1|root,COG0511@1|root,COG0439@2|Bacteria,COG0511@2|Bacteria,1N71M@1224|Proteobacteria,1RYJ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG0439 Biotin carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_7306599_1	243231.GSU3299	6.487e-224	709.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,43TAX@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS3_k127_7306599_18	358823.DF19_14610	1.151e-19	105.0	COG3502@1|root,COG3502@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF952)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
CMS3_k127_7306599_7	471852.Tcur_4809	1.499e-98	349.0	2DB85@1|root,2Z7Q2@2|Bacteria,2GTBY@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_7306599_9	1292034.OR37_01981	3.225e-85	296.0	COG1960@1|root,COG1960@2|Bacteria,1R7HF@1224|Proteobacteria,2U3BJ@28211|Alphaproteobacteria,2KID4@204458|Caulobacterales	204458|Caulobacterales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_7306599_6	402881.Plav_1805	8.102e-99	357.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_731064_11	290397.Adeh_4320	5.685e-32	135.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,2YVMB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_731064_0	667014.Thein_1862	1.989e-274	869.0	COG0466@1|root,COG0466@2|Bacteria,2GH8Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_731064_8	1121918.ARWE01000001_gene3464	9.603e-51	208.0	COG0683@1|root,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,43S82@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
CMS3_k127_731064_4	1232410.KI421424_gene1723	4.391e-135	442.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_731064_1	269799.Gmet_3532	2.138e-254	797.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_731064_12	471223.GWCH70_2438	6.34e-31	140.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,1WG1T@129337|Geobacillus	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS3_k127_731064_6	644282.Deba_2064	4.145e-60	222.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CMS3_k127_731064_5	338966.Ppro_1304	7.344e-70	271.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,43SZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS3_k127_731064_2	1242864.D187_004673	7.049e-164	564.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_731064_7	1197906.CAJQ02000051_gene46	3.798e-51	187.0	COG2128@1|root,COG2128@2|Bacteria,1MWWX@1224|Proteobacteria,2TQPH@28211|Alphaproteobacteria,3JRFX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_731064_10	1304878.AUGD01000001_gene397	3.868e-33	133.0	COG1733@1|root,COG1733@2|Bacteria,1N0WG@1224|Proteobacteria,2U9MA@28211|Alphaproteobacteria,3K082@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS3_k127_731064_3	412597.AEPN01000005_gene1500	1.776e-148	501.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2PUGP@265|Paracoccus	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_731064_9	1408311.JNJM01000001_gene266	2.213e-33	150.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,2PQT0@265975|Oribacterium	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_731064_14	1089548.KI783301_gene346	4.626e-05	46.0	2EG8N@1|root,33A0G@2|Bacteria,1VP0T@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_731064_13	1123037.AUDE01000030_gene3201	9.048e-24	102.0	COG1479@1|root,COG2865@1|root,COG3472@1|root,COG1479@2|Bacteria,COG2865@2|Bacteria,COG3472@2|Bacteria,4NHBY@976|Bacteroidetes,1HYTG@117743|Flavobacteriia	976|Bacteroidetes	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
CMS3_k127_7315159_19	933115.GPDM_00660	2.443e-65	230.0	COG3340@1|root,COG3340@2|Bacteria,1TRBA@1239|Firmicutes,4HB19@91061|Bacilli,26EDR@186818|Planococcaceae	91061|Bacilli	E	Belongs to the peptidase S51 family	ygaJ	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
CMS3_k127_7315159_23	497964.CfE428DRAFT_0785	2.627e-60	226.0	2BWCM@1|root,2ZKMD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7315159_10	378806.STAUR_6807	1.052e-91	314.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,42SXE@68525|delta/epsilon subdivisions,2WUXE@28221|Deltaproteobacteria,2YUTE@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
CMS3_k127_7315159_32	1095767.CAHD01000030_gene1065	5.503e-32	141.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4F0YY@85016|Cellulomonadaceae	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS3_k127_7315159_13	562970.Btus_0350	1.471e-80	283.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli,278UF@186823|Alicyclobacillaceae	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7315159_18	1280950.HJO_09604	1.175e-70	259.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2UAWF@28211|Alphaproteobacteria,43X26@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS3_k127_7315159_4	243231.GSU1175	2.256e-147	478.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43SUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt-1	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS3_k127_7315159_26	321327.CYA_0798	3.269e-44	172.0	COG0328@1|root,COG0328@2|Bacteria,1G12J@1117|Cyanobacteria,1GYK3@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS3_k127_7315159_1	710687.KI912270_gene3643	4.618e-231	737.0	COG0243@1|root,COG0243@2|Bacteria,2I8HX@201174|Actinobacteria,236SZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_7315159_12	251221.35211202	1.693e-87	312.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
CMS3_k127_7315159_21	1210884.HG799462_gene8246	8.423e-64	235.0	COG0580@1|root,COG0580@2|Bacteria,2IZDN@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
CMS3_k127_7315159_33	318424.EU78_14055	6.08e-30	138.0	COG0778@1|root,COG0778@2|Bacteria,2GM9M@201174|Actinobacteria,235BZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_7315159_24	1192034.CAP_8078	1.795e-54	195.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS3_k127_7315159_15	1313172.YM304_12040	7.999e-78	271.0	COG0491@1|root,COG0491@2|Bacteria,2IBQF@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
CMS3_k127_7315159_28	1496688.ER33_14360	5.687e-40	171.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,22TP7@167375|Cyanobium	1117|Cyanobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_7315159_22	502025.Hoch_2669	3.651e-63	231.0	COG5653@1|root,COG5653@2|Bacteria,1NN79@1224|Proteobacteria,42ZVH@68525|delta/epsilon subdivisions,2WVIB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_7315159_35	572477.Alvin_2117	4.156e-18	100.0	COG2940@1|root,COG2940@2|Bacteria,1N2WJ@1224|Proteobacteria,1TJR6@1236|Gammaproteobacteria,1WYYZ@135613|Chromatiales	135613|Chromatiales	S	pfam set	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
CMS3_k127_7315159_27	215803.DB30_0689	5.702e-43	174.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WIMQ@28221|Deltaproteobacteria,2YYKM@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	CarS-like,Metallophos
CMS3_k127_7315159_37	1111479.AXAR01000001_gene316	3.809e-08	65.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
CMS3_k127_7315159_38	459495.SPLC1_S140080	2.324e-06	57.0	COG0457@1|root,COG0457@2|Bacteria	459495.SPLC1_S140080|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7315159_14	1048339.KB913029_gene1211	4.918e-79	269.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4ETYD@85013|Frankiales	201174|Actinobacteria	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
CMS3_k127_7315159_36	1565129.JSFF01000001_gene1004	3.918e-15	84.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria,2Q9Z9@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS3_k127_7315159_34	1485545.JQLW01000008_gene1909	1.548e-20	106.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	yhcB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS3_k127_7315159_29	290397.Adeh_0265	1.7e-38	167.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2YUX4@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	coaE	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CoaE,PseudoU_synth_2,S4
CMS3_k127_7315159_2	641524.ADICYQ_5666	2.848e-158	517.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,47JWF@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_7315159_5	909663.KI867149_gene3370	7.695e-147	496.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_7315159_8	85643.Tmz1t_1472	7.783e-103	353.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,2VKGU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CMS3_k127_7315159_30	502025.Hoch_4562	9.202e-37	148.0	COG3427@1|root,COG3427@2|Bacteria,1PJ50@1224|Proteobacteria,4331V@68525|delta/epsilon subdivisions,2WYE1@28221|Deltaproteobacteria,2Z1MD@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG
CMS3_k127_7315159_7	1207063.P24_09936	1.844e-106	372.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2TSXR@28211|Alphaproteobacteria,2JR83@204441|Rhodospirillales	204441|Rhodospirillales	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_7315159_6	1380394.JADL01000011_gene3986	8.658e-124	412.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria,2JQDG@204441|Rhodospirillales	204441|Rhodospirillales	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS3_k127_7315159_16	570967.JMLV01000001_gene2710	2.491e-75	286.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TRA8@28211|Alphaproteobacteria,2JQRH@204441|Rhodospirillales	204441|Rhodospirillales	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_7315159_0	1380394.JADL01000011_gene3988	0.0	1165.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JQ9H@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_7315159_20	1207063.P24_04724	9.487e-65	244.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,2JS2Q@204441|Rhodospirillales	204441|Rhodospirillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_7315159_11	479434.Sthe_0987	2.303e-89	327.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi,27XTC@189775|Thermomicrobia	189775|Thermomicrobia	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
CMS3_k127_7315159_31	570268.ANBB01000046_gene1362	6.734e-34	152.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4EGYG@85012|Streptosporangiales	201174|Actinobacteria	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_7315159_3	1379270.AUXF01000004_gene3285	5.865e-148	484.0	COG0277@1|root,COG0277@2|Bacteria,1ZT11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_7315159_25	404589.Anae109_1471	1.844e-50	195.0	COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
CMS3_k127_7315159_9	298654.FraEuI1c_3291	3.154e-100	336.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_7315159_17	1168065.DOK_08259	1.746e-71	249.0	2DBBP@1|root,2Z88Z@2|Bacteria,1R3B4@1224|Proteobacteria,1RSHG@1236|Gammaproteobacteria,1J5IE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_7363113_1	330214.NIDE1515	7.604e-93	313.0	COG0312@1|root,COG0312@2|Bacteria,3J0P7@40117|Nitrospirae	40117|Nitrospirae	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_7363113_4	109760.SPPG_00211T0	5.458e-62	225.0	COG0491@1|root,KOG0813@2759|Eukaryota,38BZ4@33154|Opisthokonta,3P10J@4751|Fungi	4751|Fungi	IQ	metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_7363113_7	1184267.A11Q_315	2.675e-45	170.0	COG2259@1|root,COG2259@2|Bacteria,1RKEE@1224|Proteobacteria,42SF5@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS3_k127_7363113_0	1155718.KB891899_gene1843	7.628e-126	417.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.21	ko:K07749,ko:K08298	-	-	R10643,R10644	RC00014,RC00131	ko00000,ko01000	-	-	-	CoA_transf_3
CMS3_k127_7363113_8	1242864.D187_009657	4.006e-45	178.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,2YVND@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_7363113_2	644282.Deba_0203	2.244e-71	262.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_7363113_3	1254432.SCE1572_04205	3.703e-62	231.0	COG0767@1|root,COG0767@2|Bacteria,1RHNJ@1224|Proteobacteria,42SNW@68525|delta/epsilon subdivisions,2WPKT@28221|Deltaproteobacteria,2YV5J@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_7363113_9	713587.THITH_14025	3.276e-42	163.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1WY2J@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS3_k127_7363113_6	667014.Thein_1638	2.81e-51	202.0	COG0325@1|root,COG0325@2|Bacteria,2GH4Z@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS3_k127_7363113_5	575540.Isop_2107	1.924e-61	222.0	COG0345@1|root,COG0345@2|Bacteria,2IY5U@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS3_k127_7386836_15	1123023.JIAI01000003_gene2889	2.632e-27	115.0	COG0500@1|root,COG2226@2|Bacteria,2IAGR@201174|Actinobacteria	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_7386836_14	671143.DAMO_0482	1.028e-31	138.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
CMS3_k127_7386836_4	1313172.YM304_20970	2.608e-112	389.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_7386836_19	1433126.BN938_0234	9.928e-06	60.0	COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,2FP40@200643|Bacteroidia,22VAS@171550|Rikenellaceae	976|Bacteroidetes	S	CAAX protease self-immunity	sagE	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_7386836_0	443143.GM18_0175	0.0	1075.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,43U3R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_7386836_17	187272.Mlg_0200	3.296e-21	108.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales	135613|Chromatiales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
CMS3_k127_7386836_5	234267.Acid_0291	1.427e-83	297.0	COG1167@1|root,COG1167@2|Bacteria,3Y4RE@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
CMS3_k127_7386836_16	1028800.RG540_CH24480	4.466e-24	120.0	COG2343@1|root,COG2343@2|Bacteria,1RHXD@1224|Proteobacteria,2UC5N@28211|Alphaproteobacteria,4BEZ3@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS3_k127_7386836_7	448385.sce6875	3.58e-75	276.0	COG1708@1|root,COG1708@2|Bacteria,1N1CX@1224|Proteobacteria,437ZI@68525|delta/epsilon subdivisions,2X39J@28221|Deltaproteobacteria,2YUYJ@29|Myxococcales	28221|Deltaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS3_k127_7386836_11	926560.KE387027_gene519	3.886e-62	232.0	COG2045@1|root,COG2045@2|Bacteria,1WMIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	2-phosphosulpholactate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	2-ph_phosp
CMS3_k127_7386836_18	1357279.N018_20235	8.959e-13	76.0	COG0695@1|root,COG0695@2|Bacteria,1N6ZT@1224|Proteobacteria,1SD1U@1236|Gammaproteobacteria,1Z7RT@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	O	Glutaredoxin	nrdH	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS3_k127_7386836_3	414684.RC1_1776	2.553e-118	393.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2JP8T@204441|Rhodospirillales	204441|Rhodospirillales	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_7386836_1	269799.Gmet_3547	3.965e-298	953.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,43TS2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS3_k127_7386836_12	1380386.JIAW01000019_gene2375	3.204e-47	178.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,2335S@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_7386836_10	909663.KI867150_gene1287	2.987e-67	240.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2MQDG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS3_k127_7386836_13	877455.Metbo_0531	5.52e-35	150.0	COG0293@1|root,arCOG00079@2157|Archaea,2XT12@28890|Euryarchaeota,23P0D@183925|Methanobacteria	183925|Methanobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS3_k127_7386836_9	338969.Rfer_2801	4.439e-68	247.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,2VQ0D@28216|Betaproteobacteria,4ADFN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
CMS3_k127_7386836_2	1177154.Y5S_00326	6.457e-246	790.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1XR7R@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_7386836_6	1385935.N836_09745	2.583e-82	284.0	COG2816@1|root,COG2816@2|Bacteria,1G3EM@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the Nudix hydrolase family. NudC subfamily	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
CMS3_k127_7386836_8	864702.OsccyDRAFT_1327	2.349e-71	266.0	2BB2J@1|root,324IQ@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS3_k127_7386836_20	1123242.JH636434_gene3949	0.0008796	48.0	COG2227@1|root,COG2227@2|Bacteria,2J0E0@203682|Planctomycetes	203682|Planctomycetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_7388362_16	1163408.UU9_06709	1.57e-10	67.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S401@1236|Gammaproteobacteria,1X396@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7388362_7	247633.GP2143_09045	2.185e-88	312.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,1JA4A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_7388362_0	247633.GP2143_09040	1.676e-318	1028.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J8T8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_7388362_15	1123514.KB905899_gene1170	4.076e-16	86.0	2CEDU@1|root,333S9@2|Bacteria,1NCM4@1224|Proteobacteria,1SDI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4156
CMS3_k127_7388362_9	1254432.SCE1572_34125	1.139e-67	237.0	COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,437YA@68525|delta/epsilon subdivisions,2X385@28221|Deltaproteobacteria,2YUSI@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS3_k127_7388362_3	1313172.YM304_21870	3.585e-142	465.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria	201174|Actinobacteria	T	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS3_k127_7388362_11	395961.Cyan7425_4219	1.643e-57	211.0	COG4360@1|root,COG4360@2|Bacteria,1G2S9@1117|Cyanobacteria,3KG1H@43988|Cyanothece	1117|Cyanobacteria	F	ATP adenylyltransferase	apa2	-	2.7.7.53	ko:K00988	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	ATP_transf
CMS3_k127_7388362_2	391625.PPSIR1_30065	5.691e-223	738.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YX5W@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_7388362_10	404380.Gbem_3145	1.462e-60	237.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,42Q1E@68525|delta/epsilon subdivisions,2WKG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	cog0421, spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_7388362_14	42256.RradSPS_0637	2.937e-16	89.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_7388362_17	1293047.CBMA010000017_gene972	0.0001915	51.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_7388362_13	83406.HDN1F_12000	1.96e-23	104.0	COG3255@1|root,COG3255@2|Bacteria,1N01E@1224|Proteobacteria,1SBCB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_7388362_1	76114.ebA4666	4.605e-235	770.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,2KVQH@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_7388362_6	373994.Riv7116_2716	2.27e-104	366.0	COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1HKTB@1161|Nostocales	1117|Cyanobacteria	U	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CMS3_k127_7388362_12	573370.DMR_30760	9.269e-31	141.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WURY@28221|Deltaproteobacteria,2MG3H@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS3_k127_7388362_4	243231.GSU1003	6.911e-128	449.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_7388362_8	269799.Gmet_2562	3.588e-68	248.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
CMS3_k127_7388362_5	706587.Desti_1674	1.569e-109	373.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2WIQI@28221|Deltaproteobacteria,2MRDH@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_7405800_33	573569.F7308_1869	3.413e-48	197.0	COG5361@1|root,COG5361@2|Bacteria,1NBVB@1224|Proteobacteria,1SES6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Neurotransmitter-gated ion-channel ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Neur_chan_LBD,Neur_chan_memb
CMS3_k127_7405800_64	338969.Rfer_0381	6.765e-09	68.0	2DWID@1|root,340GN@2|Bacteria,1ND9Q@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7405800_32	378806.STAUR_5561	8.974e-49	199.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WM20@28221|Deltaproteobacteria,2YYXK@29|Myxococcales	28221|Deltaproteobacteria	M	Tetraacyldisaccharide-1-P 4'-kinase	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS3_k127_7405800_26	1125863.JAFN01000001_gene3417	4.212e-72	262.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS3_k127_7405800_25	335543.Sfum_3751	2.954e-72	274.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MQCW@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS3_k127_7405800_27	1121405.dsmv_3143	1.559e-69	265.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,2MHUD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM oxidoreductase domain protein	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_7405800_29	589865.DaAHT2_0858	1.731e-61	222.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria,2MHT1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
CMS3_k127_7405800_23	378806.STAUR_5574	1.604e-74	266.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria,2YYET@29|Myxococcales	28221|Deltaproteobacteria	M	Udp N-acetylglucosamine O-acyltransferase; Domain 2	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS3_k127_7405800_71	655815.ZPR_0033	0.0005593	49.0	COG2825@1|root,COG2825@2|Bacteria,4NMEY@976|Bacteroidetes,1IMJF@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS3_k127_7405800_10	243231.GSU2268	5.826e-126	447.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,43UEF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_7405800_24	243231.GSU2269	3.507e-74	260.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS3_k127_7405800_16	56780.SYN_00923	9.167e-89	318.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS3_k127_7405800_12	1499967.BAYZ01000084_gene3994	5.099e-120	396.0	COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_7405800_20	671143.DAMO_0676	5.931e-79	291.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_7405800_45	404589.Anae109_2711	7.916e-26	123.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42TCJ@68525|delta/epsilon subdivisions,2X5PW@28221|Deltaproteobacteria,2Z2ZQ@29|Myxococcales	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS3_k127_7405800_14	1121456.ATVA01000013_gene851	1.909e-104	368.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2M8FH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM PhoH family protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS3_k127_7405800_43	290397.Adeh_2722	9.204e-33	144.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_7405800_66	246197.MXAN_4740	1.346e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,1P92T@1224|Proteobacteria,4331J@68525|delta/epsilon subdivisions,2WYEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7405800_55	709032.Sulku_0104	7.5e-17	84.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2YPUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS3_k127_7405800_57	1121468.AUBR01000023_gene2769	2.389e-16	93.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,42G45@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS3_k127_7405800_68	794903.OPIT5_03350	1.263e-06	58.0	2DI9S@1|root,302GQ@2|Bacteria,46YIP@74201|Verrucomicrobia,3K8AM@414999|Opitutae	414999|Opitutae	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
CMS3_k127_7405800_34	443144.GM21_0765	2.812e-46	182.0	COG2199@1|root,COG3706@2|Bacteria,1MZZV@1224|Proteobacteria,42UXH@68525|delta/epsilon subdivisions,2WVP3@28221|Deltaproteobacteria,43SMM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_7405800_28	443143.GM18_3601	3.266e-67	253.0	COG2203@1|root,COG2203@2|Bacteria,1RJ35@1224|Proteobacteria,42T0K@68525|delta/epsilon subdivisions,2WPIM@28221|Deltaproteobacteria,43T60@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3
CMS3_k127_7405800_15	443143.GM18_3602	7.134e-94	330.0	COG2201@1|root,COG2201@2|Bacteria,1R5IM@1224|Proteobacteria,42Q4X@68525|delta/epsilon subdivisions,2WMDB@28221|Deltaproteobacteria,43T38@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB40H-1	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS3_k127_7405800_18	269799.Gmet_2305	1.839e-84	292.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,43UG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS3_k127_7405800_30	243231.GSU2216	1.375e-59	236.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,43UH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CMS3_k127_7405800_44	404380.Gbem_0745	7.498e-26	120.0	COG0745@1|root,COG0745@2|Bacteria	404380.Gbem_0745|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7405800_22	1297742.A176_05463	1.318e-76	287.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CMS3_k127_7405800_58	338966.Ppro_3106	1.431e-15	83.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5TT@28221|Deltaproteobacteria,43V4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS3_k127_7405800_61	1390370.O203_20955	8.582e-15	89.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1S4DQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	Chemotaxis protein CheW	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS3_k127_7405800_5	398767.Glov_2123	7.769e-157	520.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS3_k127_7405800_40	269799.Gmet_2312	9.02e-42	158.0	COG0745@1|root,COG0745@2|Bacteria,1N1TA@1224|Proteobacteria,42V03@68525|delta/epsilon subdivisions,2WPZR@28221|Deltaproteobacteria,43V4S@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	cheY40H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_7405800_37	443143.GM18_3612	1.191e-44	183.0	COG0745@1|root,COG0745@2|Bacteria,1N9YT@1224|Proteobacteria,42W15@68525|delta/epsilon subdivisions,2WS2V@28221|Deltaproteobacteria,43T56@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	regulator, PATAN and FRGAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
CMS3_k127_7405800_65	502025.Hoch_3482	1.316e-08	67.0	2BPA6@1|root,32I21@2|Bacteria,1Q1NP@1224|Proteobacteria,437D0@68525|delta/epsilon subdivisions,2X2J2@28221|Deltaproteobacteria,2YVZ4@29|Myxococcales	28221|Deltaproteobacteria	S	Cytosol aminopeptidase family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M17_N
CMS3_k127_7405800_49	344747.PM8797T_24081	5.699e-22	109.0	COG0781@1|root,COG0781@2|Bacteria,2J058@203682|Planctomycetes	203682|Planctomycetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB,PHP
CMS3_k127_7405800_41	1235279.C772_00367	2.487e-39	166.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,26EVD@186818|Planococcaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
CMS3_k127_7405800_19	1121861.KB899938_gene4011	2.184e-79	298.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2JPG9@204441|Rhodospirillales	204441|Rhodospirillales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS3_k127_7405800_38	1125863.JAFN01000001_gene32	7.278e-44	165.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS3_k127_7405800_3	269799.Gmet_1605	9.526e-170	543.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43U6J@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_7405800_48	858215.Thexy_1359	2.94e-23	104.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,42H5S@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_7405800_17	926566.Terro_3859	3.328e-87	298.0	COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria,2JI6J@204432|Acidobacteriia	204432|Acidobacteriia	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS3_k127_7405800_51	338963.Pcar_1434	8.506e-20	92.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS3_k127_7405800_54	667014.Thein_1723	5.735e-18	94.0	COG1399@1|root,COG1399@2|Bacteria,2GHV8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS3_k127_7405800_7	545276.KB898731_gene2203	2.069e-137	455.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS3_k127_7405800_36	1123499.KB908018_gene2056	5.23e-45	174.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,2KQDU@206351|Neisseriales	206351|Neisseriales	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS3_k127_7405800_35	330214.NIDE3434	6.337e-46	177.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS3_k127_7405800_21	330214.NIDE3435	5.477e-78	276.0	COG1131@1|root,COG1131@2|Bacteria,3J122@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7405800_46	1242864.D187_006602	1.372e-23	113.0	COG0457@1|root,COG0457@2|Bacteria,1MZCR@1224|Proteobacteria,42R7I@68525|delta/epsilon subdivisions,2WMT6@28221|Deltaproteobacteria,2YW4K@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	pilG	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7405800_62	1121396.KB893057_gene2516	7.805e-13	79.0	COG4968@1|root,COG4968@2|Bacteria,1QNMD@1224|Proteobacteria,43A72@68525|delta/epsilon subdivisions,2WYJP@28221|Deltaproteobacteria,2MNPY@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
CMS3_k127_7405800_60	1144275.COCOR_06280	6.716e-15	83.0	COG4968@1|root,COG4968@2|Bacteria,1QXV9@1224|Proteobacteria,42VR9@68525|delta/epsilon subdivisions,2WRJV@28221|Deltaproteobacteria,2YW4P@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilin PilA	pilA	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
CMS3_k127_7405800_70	263815.XP_007875419.1	2.796e-05	54.0	COG1949@1|root,KOG3242@2759|Eukaryota,39R06@33154|Opisthokonta,3NYIP@4751|Fungi,3QUDD@4890|Ascomycota,3MD2J@451866|Taphrinomycotina	4751|Fungi	L	RNA exonuclease	rex2	GO:0000002,GO:0000175,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016073,GO:0016180,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034472,GO:0034475,GO:0034476,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CMS3_k127_7405800_53	1033802.SSPSH_000651	1.374e-18	100.0	COG0515@1|root,COG0515@2|Bacteria,1NJ1M@1224|Proteobacteria,1SZWI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7405800_52	1267535.KB906767_gene442	1.101e-19	97.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria,2JJJZ@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_7405800_63	452637.Oter_3684	2.433e-12	77.0	COG1595@1|root,COG1595@2|Bacteria,46Y89@74201|Verrucomicrobia,3K93Q@414999|Opitutae	414999|Opitutae	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7405800_59	667632.KB890177_gene4299	5.825e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,1K1T9@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7405800_0	1207063.P24_04215	0.0	1077.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,2JP8K@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_7405800_4	158189.SpiBuddy_1951	2.062e-159	524.0	COG0423@1|root,COG0423@2|Bacteria,2J57N@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS3_k127_7405800_47	1232410.KI421418_gene2186	2.291e-23	115.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,43SHT@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Recombination protein O C terminal	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS3_k127_7405800_69	502025.Hoch_3558	2.223e-06	60.0	COG1426@1|root,COG1426@2|Bacteria,1NIQS@1224|Proteobacteria,4387Z@68525|delta/epsilon subdivisions,2X3HR@28221|Deltaproteobacteria,2YW5H@29|Myxococcales	28221|Deltaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
CMS3_k127_7405800_67	575588.ACPN01000003_gene1182	2.212e-07	63.0	COG3063@1|root,COG3063@2|Bacteria,1RAFJ@1224|Proteobacteria,1S5H6@1236|Gammaproteobacteria,3NT5Q@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Tetratricopeptide repeat	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_7405800_1	570268.ANBB01000033_gene2120	5.473e-222	710.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4EFQQ@85012|Streptosporangiales	201174|Actinobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_7405800_9	671143.DAMO_1620	2.051e-131	429.0	COG1013@1|root,COG1013@2|Bacteria,2NPAM@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_7405800_56	59196.RICGR_0068	9.776e-17	94.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SC7S@1236|Gammaproteobacteria,1JEZ1@118969|Legionellales	118969|Legionellales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS3_k127_7405800_39	1254432.SCE1572_18080	1.752e-43	177.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,434QI@68525|delta/epsilon subdivisions,2X8Z6@28221|Deltaproteobacteria,2Z152@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7405800_11	1125863.JAFN01000001_gene1772	4.062e-123	401.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
CMS3_k127_7405800_6	1125863.JAFN01000001_gene1773	2.863e-141	475.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
CMS3_k127_7405800_8	338966.Ppro_2327	1.89e-131	427.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,43RZ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1360	Ldh_1_C,Ldh_1_N
CMS3_k127_7405800_2	1125863.JAFN01000001_gene2870	1.377e-202	651.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS3_k127_7405800_31	1125863.JAFN01000001_gene2873	1.79e-55	212.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q9F@68525|delta/epsilon subdivisions,2WMM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS3_k127_7405800_50	1123519.PSJM300_12310	4.084e-20	105.0	COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria,1YZRC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
CMS3_k127_7405800_42	1121374.KB891576_gene387	1.984e-35	152.0	2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
CMS3_k127_7415511_34	42256.RradSPS_0211	1.372e-28	117.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_7415511_3	1128421.JAGA01000002_gene850	8.062e-206	656.0	COG3044@1|root,COG3044@2|Bacteria,2NNSZ@2323|unclassified Bacteria	2|Bacteria	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
CMS3_k127_7415511_31	247634.GPB2148_1830	1.143e-38	148.0	COG0599@1|root,COG0599@2|Bacteria,1N3YN@1224|Proteobacteria,1SBNX@1236|Gammaproteobacteria,1JB03@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_7415511_23	1123393.KB891330_gene898	5.254e-49	186.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,1KSVB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS3_k127_7415511_27	710685.MycrhN_4139	1.674e-41	163.0	2A6ZN@1|root,30VUS@2|Bacteria,2H1PU@201174|Actinobacteria,23D4W@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_7415511_42	1048339.KB913029_gene726	3.525e-09	66.0	COG1309@1|root,COG1309@2|Bacteria,2HU46@201174|Actinobacteria,4EWXF@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7415511_9	298655.KI912266_gene4051	1.709e-125	424.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_7415511_1	1041522.MCOL_V206100	4.001e-243	795.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,23787@1762|Mycobacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_7415511_11	298655.KI912266_gene673	2.509e-117	402.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria,4EUJC@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_7415511_30	644282.Deba_1036	3.138e-39	156.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,43B3M@68525|delta/epsilon subdivisions,2X6HF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_7415511_5	266265.Bxe_A3602	7.501e-167	535.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2WDWK@28216|Betaproteobacteria,1KB58@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_7415511_10	2002.JOEQ01000005_gene3373	7.053e-124	410.0	28KAT@1|root,2Z9XX@2|Bacteria,2GNVW@201174|Actinobacteria,4ENJ3@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7415511_21	243233.MCA0111	1.7e-55	219.0	28NTV@1|root,2ZBSB@2|Bacteria,1RCH7@1224|Proteobacteria,1S2MM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7415511_4	1229780.BN381_170018	3.748e-182	585.0	COG1141@1|root,COG2124@1|root,COG1141@2|Bacteria,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,3UWWV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Cytochrome P450	cyp51	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615	1.14.13.70	ko:K05917	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101	R05640,R05731	RC01442	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
CMS3_k127_7415511_26	234267.Acid_1770	4.104e-43	174.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
CMS3_k127_7415511_37	1123279.ATUS01000001_gene2757	7.11e-19	98.0	COG1309@1|root,COG1309@2|Bacteria,1RIYI@1224|Proteobacteria,1S83E@1236|Gammaproteobacteria,1JB0P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7415511_16	269799.Gmet_2217	1.467e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,42ZR2@68525|delta/epsilon subdivisions,2WV3H@28221|Deltaproteobacteria,43V3V@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	KR domain	-	-	1.1.1.51	ko:K05296	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	-	R01836,R01838,R02352,R02353,R03406,R03407,R09956,R09957	RC00127,RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS3_k127_7415511_40	298654.FraEuI1c_3435	1.331e-17	96.0	COG5517@1|root,COG5517@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS3_k127_7415511_20	1122599.AUGR01000005_gene1926	6.171e-57	220.0	COG3917@1|root,COG3917@2|Bacteria,1RJFB@1224|Proteobacteria,1S772@1236|Gammaproteobacteria,1XS50@135619|Oceanospirillales	135619|Oceanospirillales	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_7415511_12	1292034.OR37_01981	2.039e-109	385.0	COG1960@1|root,COG1960@2|Bacteria,1R7HF@1224|Proteobacteria,2U3BJ@28211|Alphaproteobacteria,2KID4@204458|Caulobacterales	204458|Caulobacterales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_7415511_7	1550073.JROH01000017_gene401	7.64e-143	479.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7415511_29	1536769.P40081_22830	7.565e-40	157.0	COG2120@1|root,COG2120@2|Bacteria,1UYGC@1239|Firmicutes,4HJGK@91061|Bacilli,26U25@186822|Paenibacillaceae	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_7415511_8	525904.Tter_1441	1.63e-131	430.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7415511_17	525904.Tter_1442	3.04e-66	258.0	COG4587@1|root,COG4587@2|Bacteria,2NQY6@2323|unclassified Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_7415511_14	525904.Tter_1443	8.554e-80	287.0	COG3694@1|root,COG3694@2|Bacteria,2NQKI@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_7415511_6	1267533.KB906735_gene4670	1.136e-165	561.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS3_k127_7415511_2	402881.Plav_2680	1.298e-232	735.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_7415511_39	404589.Anae109_1817	9.477e-18	98.0	29DN4@1|root,300JX@2|Bacteria,1Q6BR@1224|Proteobacteria,432TI@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7415511_0	886293.Sinac_6536	3.349e-288	926.0	COG0567@1|root,COG0567@2|Bacteria,2IWRF@203682|Planctomycetes	203682|Planctomycetes	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS3_k127_7415511_22	215803.DB30_6390	6.841e-55	198.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,42SXE@68525|delta/epsilon subdivisions,2WP6W@28221|Deltaproteobacteria,2YXS6@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS3_k127_7415511_38	926550.CLDAP_22580	1.525e-18	98.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
CMS3_k127_7415511_19	502025.Hoch_1713	3.947e-61	225.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
CMS3_k127_7415511_25	1313304.CALK_0635	9.866e-45	178.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_7415511_28	886293.Sinac_0815	3.701e-41	168.0	COG0561@1|root,COG0561@2|Bacteria,2J0VT@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS3_k127_7415511_18	997346.HMPREF9374_1664	2.699e-62	225.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,27AV9@186824|Thermoactinomycetaceae	91061|Bacilli	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS3_k127_7415511_24	177437.HRM2_13960	2.144e-45	176.0	COG3005@1|root,COG3005@2|Bacteria,1RHMA@1224|Proteobacteria,43DN4@68525|delta/epsilon subdivisions,2X6GA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_7415511_33	945713.IALB_1840	2.692e-32	143.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
CMS3_k127_7415511_36	243231.GSU1648	3.937e-21	109.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
CMS3_k127_7415511_13	243231.GSU1649	3.727e-89	306.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
CMS3_k127_7415511_35	443143.GM18_0922	1.38e-23	117.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
CMS3_k127_7415511_43	378806.STAUR_5457	2.768e-06	60.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	rgfB	-	3.1.3.90	ko:K06896	ko00500,map00500	-	R10486	RC00017	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
CMS3_k127_7415511_32	1282356.H045_18480	2.507e-36	144.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1SBPT@1236|Gammaproteobacteria,1YNY4@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_4,ACT_6
CMS3_k127_7415511_15	439235.Dalk_0909	8.444e-76	259.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,42PNZ@68525|delta/epsilon subdivisions,2WM13@28221|Deltaproteobacteria,2MJSE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS3_k127_7429745_17	1411123.JQNH01000001_gene767	2.225e-50	202.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
CMS3_k127_7429745_6	62928.azo1567	1.574e-136	467.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVVB@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,MASE1
CMS3_k127_7429745_23	1192034.CAP_1503	2.432e-25	119.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,434YV@68525|delta/epsilon subdivisions,2WZ9S@28221|Deltaproteobacteria,2Z1NI@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7429745_5	1379701.JPJC01000141_gene28	1.844e-153	498.0	COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,2TTIQ@28211|Alphaproteobacteria,2K0FP@204457|Sphingomonadales	204457|Sphingomonadales	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
CMS3_k127_7429745_11	502025.Hoch_2049	1.322e-75	283.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,42PS4@68525|delta/epsilon subdivisions,2WM4V@28221|Deltaproteobacteria,2YUI4@29|Myxococcales	28221|Deltaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CMS3_k127_7429745_1	502025.Hoch_2050	4.556e-208	657.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,42MA8@68525|delta/epsilon subdivisions,2WIXR@28221|Deltaproteobacteria,2YUA9@29|Myxococcales	28221|Deltaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
CMS3_k127_7429745_0	648757.Rvan_1139	0.0	1461.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2TSVH@28211|Alphaproteobacteria,3N6I3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	MA20_16195	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
CMS3_k127_7429745_3	502025.Hoch_2048	1.429e-186	601.0	COG0121@1|root,COG1305@1|root,COG0121@2|Bacteria,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,42PJK@68525|delta/epsilon subdivisions,2WMCS@28221|Deltaproteobacteria,2YU92@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,GATase_4,Transglut_core
CMS3_k127_7429745_10	404589.Anae109_0210	2.151e-77	271.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,2Z2XX@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_7429745_4	1254432.SCE1572_11670	6.223e-154	534.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2WJCJ@28221|Deltaproteobacteria,2Z2S1@29|Myxococcales	28221|Deltaproteobacteria	G	Fructose-bisphosphate aldolase class-II	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CMS3_k127_7429745_18	1403819.BATR01000164_gene5524	2.686e-49	183.0	COG0454@1|root,COG0456@2|Bacteria,46SWZ@74201|Verrucomicrobia,2IVZ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_7429745_20	745014.OMB55_00025130	1.715e-29	134.0	COG3687@1|root,COG3687@2|Bacteria,1RFZ0@1224|Proteobacteria,1SN3T@1236|Gammaproteobacteria,1JBSA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted metal-dependent hydrolase	-	-	-	ko:K07044	-	-	-	-	ko00000	-	-	-	Metal_hydrol
CMS3_k127_7429745_27	649638.Trad_0294	5.841e-11	75.0	COG4424@1|root,COG4424@2|Bacteria,1WN1P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Sulfotransferase family	-	-	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
CMS3_k127_7429745_24	1380355.JNIJ01000047_gene219	3.782e-24	115.0	COG0346@1|root,COG0346@2|Bacteria,1RIBY@1224|Proteobacteria,2UAVN@28211|Alphaproteobacteria,3K1HK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_7429745_25	1265313.HRUBRA_02550	1.643e-22	100.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,1S4K1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_7429745_28	566466.NOR53_2255	8.147e-08	66.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,1S4K1@1236|Gammaproteobacteria,1J9BV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_7429745_26	1384056.N787_06710	3.869e-11	76.0	2BKVA@1|root,32FBN@2|Bacteria,1QCVY@1224|Proteobacteria,1T8PK@1236|Gammaproteobacteria,1XB1P@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
CMS3_k127_7429745_2	1173264.KI913949_gene3646	3.512e-193	613.0	COG0017@1|root,COG0017@2|Bacteria,1G015@1117|Cyanobacteria,1H7PZ@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_7429745_9	1232410.KI421415_gene3084	7.601e-85	294.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,42N0B@68525|delta/epsilon subdivisions,2WN21@28221|Deltaproteobacteria,43TU2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
CMS3_k127_7429745_14	443144.GM21_1115	1.298e-67	247.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42QQS@68525|delta/epsilon subdivisions,2WMUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS3_k127_7429745_8	1210884.HG799466_gene12816	4.725e-90	329.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_7429745_29	710111.FraQA3DRAFT_0406	2.346e-06	54.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	bfd	-	-	ko:K00360,ko:K02192	ko00910,ko01120,map00910,map01120	M00531	R00798	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Pyr_redox_2
CMS3_k127_7429745_16	1192034.CAP_7171	9.414e-52	187.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2Z32M@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS3_k127_7429745_22	485913.Krac_1031	1.926e-26	126.0	COG2133@1|root,COG2133@2|Bacteria,2G90Z@200795|Chloroflexi	200795|Chloroflexi	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7429745_21	867845.KI911784_gene3105	2.602e-28	119.0	COG3703@1|root,COG3703@2|Bacteria	2|Bacteria	P	gamma-glutamylcyclotransferase activity	ykqA	-	-	-	-	-	-	-	-	-	-	-	AIG2_2,GGACT
CMS3_k127_7429745_7	215803.DB30_0854	4.046e-121	424.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_7429745_13	1349820.M707_14690	1.654e-69	248.0	COG0451@1|root,COG0451@2|Bacteria,2IF2Z@201174|Actinobacteria,1W9DZ@1268|Micrococcaceae	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
CMS3_k127_7429745_19	290397.Adeh_0076	9.249e-40	158.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,43B6K@68525|delta/epsilon subdivisions,2X6K5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS3_k127_7429745_12	96561.Dole_2499	1.47e-73	259.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2MIMI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_7429745_15	1157708.KB907450_gene5229	6.626e-60	215.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,2VQEC@28216|Betaproteobacteria,4ADVM@80864|Comamonadaceae	28216|Betaproteobacteria	F	Peptidase C26	guaA_2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS3_k127_7525788_4	867845.KI911784_gene357	2.315e-19	102.0	COG1807@1|root,COG1807@2|Bacteria,2GA9N@200795|Chloroflexi,374X1@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7525788_3	335543.Sfum_0219	1.197e-53	207.0	COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_7525788_2	1379698.RBG1_1C00001G1816	3.301e-79	300.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
CMS3_k127_7525788_1	644968.DFW101_0883	2.508e-179	626.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2M99V@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_7525788_0	391625.PPSIR1_28323	1.487e-211	671.0	COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,42YMX@68525|delta/epsilon subdivisions,2WTJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	tRNA synthetases class I (K)	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
CMS3_k127_7527997_0	1242864.D187_006298	1.593e-93	318.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS3_k127_7527997_1	1304872.JAGC01000003_gene3640	4.49e-69	260.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,2M87D@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS3_k127_7527997_2	582515.KR51_00007010	1.788e-40	170.0	COG0691@1|root,COG0691@2|Bacteria,1G542@1117|Cyanobacteria	1117|Cyanobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS3_k127_7527997_4	1379270.AUXF01000001_gene2412	6.415e-05	56.0	COG5549@1|root,COG5549@2|Bacteria,1ZTQC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Matrixin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
CMS3_k127_7527997_3	1176165.CAJD01000019_gene1579	1.25e-06	60.0	COG4223@1|root,COG4223@2|Bacteria,2I7ST@201174|Actinobacteria,4FB8V@85019|Brevibacteriaceae	201174|Actinobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7536848_2	366602.Caul_3553	9.016e-57	207.0	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,2TVH5@28211|Alphaproteobacteria,2KGC5@204458|Caulobacterales	204458|Caulobacterales	J	PFAM tRNA rRNA methyltransferase (SpoU)	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CMS3_k127_7536848_0	1144275.COCOR_02760	8.348e-250	800.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria,2YUMS@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
CMS3_k127_7536848_3	1150599.MPHLEI_09919	2.004e-53	200.0	COG2141@1|root,COG2141@2|Bacteria,2IBDS@201174|Actinobacteria,2368G@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_7536848_1	264462.Bd0967	4.698e-145	487.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42NID@68525|delta/epsilon subdivisions,2MSNJ@213481|Bdellovibrionales,2WJ4P@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CMS3_k127_7536848_4	448385.sce6471	1.233e-38	152.0	COG0278@1|root,COG0316@1|root,COG0607@1|root,COG0278@2|Bacteria,COG0316@2|Bacteria,COG0607@2|Bacteria,1MZ4V@1224|Proteobacteria,43154@68525|delta/epsilon subdivisions,2WWCI@28221|Deltaproteobacteria,2YVCT@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin,Rhodanese
CMS3_k127_7558807_9	1118235.CAJH01000021_gene1296	6.92e-40	152.0	COG0278@1|root,COG0316@1|root,COG0607@1|root,COG0278@2|Bacteria,COG0316@2|Bacteria,COG0607@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1X4PV@135614|Xanthomonadales	135614|Xanthomonadales	OP	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin,Rhodanese
CMS3_k127_7558807_10	1283300.ATXB01000002_gene3087	1.357e-14	81.0	COG0271@1|root,COG0271@2|Bacteria,1P2CW@1224|Proteobacteria,1STFH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	BolA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS3_k127_7558807_1	234267.Acid_5969	1.875e-168	546.0	COG0076@1|root,COG0076@2|Bacteria,3Y365@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS3_k127_7558807_3	1394178.AWOO02000012_gene3716	4e-111	396.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_7558807_4	1120792.JAFV01000001_gene2343	2.629e-105	355.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,3700Y@31993|Methylocystaceae	28211|Alphaproteobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3,1.1.3.46,1.13.12.4	ko:K00101,ko:K00467,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R00319,R06633	RC00044,RC00240,RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
CMS3_k127_7558807_6	502025.Hoch_5491	1.838e-87	305.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,437RC@68525|delta/epsilon subdivisions,2X304@28221|Deltaproteobacteria,2YTVQ@29|Myxococcales	28221|Deltaproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PCMT
CMS3_k127_7558807_7	502025.Hoch_6860	9.22e-77	284.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,43AKE@68525|delta/epsilon subdivisions,2WMV2@28221|Deltaproteobacteria,2YZQY@29|Myxococcales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_7558807_0	1313172.YM304_27360	9.94e-171	563.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_7558807_5	436229.JOEH01000007_gene3910	8.496e-89	303.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_7558807_8	1416759.AYMR01000013_gene2489	2.092e-62	223.0	COG1082@1|root,COG1082@2|Bacteria,2IH92@201174|Actinobacteria,4FNB9@85023|Microbacteriaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_7558807_2	717606.PaecuDRAFT_1393	9.159e-123	416.0	COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,4HBTG@91061|Bacilli,26QSD@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
CMS3_k127_7589467_3	390874.Tpet_1783	6.12e-10	63.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS3_k127_7589467_1	338963.Pcar_2400	7.843e-75	263.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria,43S7Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS3_k127_7589467_0	685727.REQ_41850	6.57e-97	328.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria,4G5D5@85025|Nocardiaceae	201174|Actinobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_7589467_2	536019.Mesop_1611	1.653e-66	239.0	COG3568@1|root,COG3568@2|Bacteria,1P2WU@1224|Proteobacteria,2U2FR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_7601597_4	1282876.BAOK01000001_gene951	1.676e-33	137.0	COG2146@1|root,COG2146@2|Bacteria,1NWKP@1224|Proteobacteria	1224|Proteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_7601597_3	1313172.YM304_37240	2.279e-37	160.0	COG1409@1|root,COG1409@2|Bacteria,2IDNH@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_7601597_0	96561.Dole_2292	1.161e-136	457.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria,2MHXR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_7601597_1	1231185.BAMP01000090_gene2468	2.601e-62	222.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,2U1K1@28211|Alphaproteobacteria,43JYC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_5,MarR_2,PadR,Replic_Relax
CMS3_k127_7601597_5	1288079.AUKN01000015_gene438	8.9e-15	85.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS3_k127_7601597_2	1357275.AVEL02000044_gene434	7.518e-45	169.0	2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria,1SABW@1236|Gammaproteobacteria,1Z7JP@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
CMS3_k127_7601597_6	1385935.N836_03240	2.301e-08	65.0	2EM9G@1|root,33EYK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7609567_0	290397.Adeh_0928	3.743e-67	260.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
CMS3_k127_7609567_1	439235.Dalk_2943	4.425e-47	183.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	COG0003 Oxyanion-translocating ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CMS3_k127_7609567_3	1121441.AUCX01000016_gene2341	6.551e-07	62.0	2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CC0@68525|delta/epsilon subdivisions,2X7XS@28221|Deltaproteobacteria,2MHJ4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4
CMS3_k127_7609567_2	1121456.ATVA01000016_gene1946	1.126e-16	83.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MD43@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_7626919_0	247634.GPB2148_1120	1.98e-188	602.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J88C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
CMS3_k127_7626919_4	1089550.ATTH01000001_gene2237	5.369e-33	139.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_7626919_5	211114.JOEF01000007_gene865	1.433e-18	95.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E3X3@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
CMS3_k127_7626919_3	1396141.BATP01000018_gene1556	1.986e-45	171.0	COG1670@1|root,COG1670@2|Bacteria,46XI2@74201|Verrucomicrobia,2IVZ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_7626919_6	698964.CDPW8_0877	1.106e-10	71.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,22KZU@1653|Corynebacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7626919_1	237368.SCABRO_03208	7.294e-93	318.0	COG4301@1|root,COG4301@2|Bacteria,2IXEH@203682|Planctomycetes	203682|Planctomycetes	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
CMS3_k127_7626919_2	1229780.BN381_410016	1.281e-64	230.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,3UWQF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
CMS3_k127_823889_4	502025.Hoch_5486	4.252e-137	447.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NXQ@68525|delta/epsilon subdivisions,2WJ9T@28221|Deltaproteobacteria,2Z34K@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_823889_7	1304275.C41B8_04631	4.941e-122	421.0	COG3660@1|root,COG3660@2|Bacteria,1R70U@1224|Proteobacteria,1S0W8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
CMS3_k127_823889_12	1125863.JAFN01000001_gene909	4.746e-87	296.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS3_k127_823889_22	1047013.AQSP01000132_gene1731	2.125e-45	188.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	-	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS3_k127_823889_18	570967.JMLV01000005_gene77	6.58e-60	219.0	COG0746@1|root,COG0746@2|Bacteria,1QWF1@1224|Proteobacteria,2TWXS@28211|Alphaproteobacteria,2JYU6@204441|Rhodospirillales	204441|Rhodospirillales	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS3_k127_823889_15	1038858.AXBA01000040_gene3078	4.585e-73	258.0	COG1409@1|root,COG1409@2|Bacteria,1MXD6@1224|Proteobacteria,2TSJ4@28211|Alphaproteobacteria,3EYUE@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_823889_16	232721.Ajs_3062	2.267e-72	277.0	COG0558@1|root,COG0558@2|Bacteria,1MYE7@1224|Proteobacteria,2WEA8@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_823889_27	314278.NB231_08948	5.701e-37	153.0	COG1597@1|root,COG1597@2|Bacteria,1RIZ6@1224|Proteobacteria,1S4KN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_823889_19	1288494.EBAPG3_18500	2.383e-57	211.0	COG1597@1|root,COG1597@2|Bacteria,1RB97@1224|Proteobacteria,2W2S3@28216|Betaproteobacteria,372M6@32003|Nitrosomonadales	28216|Betaproteobacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_823889_26	713586.KB900536_gene2013	1.887e-38	161.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_823889_21	391625.PPSIR1_07083	3.418e-50	190.0	COG0300@1|root,COG0300@2|Bacteria,1RGKZ@1224|Proteobacteria,43BQ7@68525|delta/epsilon subdivisions,2X7IJ@28221|Deltaproteobacteria,2Z3IA@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_823889_24	1122611.KB903951_gene6211	1.042e-44	173.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4EGBS@85012|Streptosporangiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_823889_23	1123024.AUII01000016_gene1256	2.274e-45	168.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_823889_1	10042.XP_006977786.1	4.011e-183	582.0	KOG1406@1|root,KOG4170@1|root,KOG1406@2759|Eukaryota,KOG4170@2759|Eukaryota,38CKQ@33154|Opisthokonta,3BDZX@33208|Metazoa,3CUCP@33213|Bilateria,483XX@7711|Chordata,48ZBY@7742|Vertebrata,3J60I@40674|Mammalia,358XR@314146|Euarchontoglires,4Q2NW@9989|Rodentia	33208|Metazoa	I	propanoyl-CoA C-acyltransferase activity	SCP2	GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911	2.3.1.176	ko:K08764	ko00120,ko01100,ko03320,ko04146,map00120,map01100,map03320,map04146	M00104	R03719,R04811	RC00004,RC00405,RC02725	ko00000,ko00001,ko00002,ko01000	-	-	-	SCP2,Thiolase_C,Thiolase_N
CMS3_k127_823889_20	1267535.KB906767_gene5001	5.429e-54	213.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_823889_11	1210884.HG799463_gene9850	2.74e-94	346.0	COG4977@1|root,COG4977@2|Bacteria,2IXH9@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K17736	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
CMS3_k127_823889_17	331869.BAL199_18238	2.652e-69	241.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,2TW75@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS3_k127_823889_28	373994.Riv7116_6584	9.84e-30	133.0	COG0633@1|root,COG0633@2|Bacteria,1G6N3@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
CMS3_k127_823889_10	1122604.JONR01000005_gene987	5.638e-102	353.0	COG1073@1|root,COG1073@2|Bacteria,1PQAX@1224|Proteobacteria,1RZIS@1236|Gammaproteobacteria,1X4J1@135614|Xanthomonadales	135614|Xanthomonadales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_823889_2	1206731.BAGB01000010_gene562	1.141e-173	572.0	COG2937@1|root,COG2937@2|Bacteria,2GMQF@201174|Actinobacteria,4FWRE@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_823889_14	502025.Hoch_5545	1.405e-80	280.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1PEHA@1224|Proteobacteria,43A38@68525|delta/epsilon subdivisions,2X24Q@28221|Deltaproteobacteria,2YW67@29|Myxococcales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	TrkA_C,TrkA_N
CMS3_k127_823889_31	926551.KB900734_gene1464	5.382e-12	74.0	COG0517@1|root,COG0517@2|Bacteria,4NQYH@976|Bacteroidetes,1I24R@117743|Flavobacteriia,1ERTQ@1016|Capnocytophaga	976|Bacteroidetes	S	CBS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_823889_6	1229780.BN381_10328	2.203e-135	468.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,3UX6E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_823889_32	6238.CBG23668	2.346e-10	72.0	KOG3873@1|root,KOG3873@2759|Eukaryota,39U5K@33154|Opisthokonta,3BGK9@33208|Metazoa,3CS5D@33213|Bilateria,40D25@6231|Nematoda,1KYHS@119089|Chromadorea,40W0U@6236|Rhabditida	33208|Metazoa	T	Endonuclease/Exonuclease/phosphatase family	SMPD2	GO:0003674,GO:0003824,GO:0004620,GO:0004767,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005901,GO:0006629,GO:0006643,GO:0006644,GO:0006665,GO:0006672,GO:0006684,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009612,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010556,GO:0010941,GO:0010942,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019216,GO:0019222,GO:0019637,GO:0023052,GO:0030148,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0034248,GO:0034250,GO:0034641,GO:0035556,GO:0042578,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043603,GO:0043604,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044853,GO:0045121,GO:0045834,GO:0046467,GO:0046513,GO:0046889,GO:0046890,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090153,GO:0090154,GO:0097164,GO:0098589,GO:0098590,GO:0098805,GO:0098857,GO:1901564,GO:1901566,GO:1901576,GO:1905038,GO:2000303,GO:2000304	3.1.4.12	ko:K12351	ko00600,ko01100,ko04071,map00600,map01100,map04071	-	R02541	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
CMS3_k127_823889_0	1313172.YM304_15200	7.319e-206	647.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4CN9Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15,4.1.2.27	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	M00027,M00100	R00261,R00489,R01682,R02464,R02466,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
CMS3_k127_823889_25	443255.SCLAV_4943	7.126e-40	154.0	COG1162@1|root,COG1162@2|Bacteria,2IMZI@201174|Actinobacteria	201174|Actinobacteria	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
CMS3_k127_823889_5	419947.MRA_1946	1.97e-135	440.0	COG2141@1|root,COG2141@2|Bacteria,2GITK@201174|Actinobacteria,236DF@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_823889_8	404589.Anae109_3037	6.828e-110	371.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2WJZA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
CMS3_k127_823889_3	1121937.AUHJ01000010_gene1707	3.632e-142	477.0	COG2159@1|root,COG2159@2|Bacteria,1PZ2I@1224|Proteobacteria,1S1Y9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_823889_13	247634.GPB2148_868	4.909e-87	309.0	COG4638@1|root,COG4638@2|Bacteria,1N1S6@1224|Proteobacteria,1S8ZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_823889_29	710686.Mycsm_04983	1.547e-28	127.0	COG1309@1|root,COG1309@2|Bacteria,2GMX0@201174|Actinobacteria,234XP@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_823889_9	266117.Rxyl_3138	4.579e-106	351.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_828693_4	443143.GM18_3640	4.667e-24	113.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
CMS3_k127_828693_3	1303518.CCALI_00205	1.794e-51	209.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
CMS3_k127_828693_2	246197.MXAN_5907	2.467e-66	250.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CMS3_k127_828693_0	1123389.ATXJ01000001_gene630	1.289e-110	386.0	COG0343@1|root,COG0343@2|Bacteria,1WI0U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS3_k127_828693_1	644966.Tmar_0853	2.497e-95	325.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WCFH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS3_k127_845450_3	1297863.APJF01000013_gene3998	4.498e-117	385.0	COG2043@1|root,COG2043@2|Bacteria,1NR18@1224|Proteobacteria,2TVGP@28211|Alphaproteobacteria,3JU0D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterised ArCR, COG2043	MA20_36865	-	-	-	-	-	-	-	-	-	-	-	DUF169
CMS3_k127_845450_8	1380386.JIAW01000007_gene3991	5.195e-38	159.0	COG1545@1|root,COG1545@2|Bacteria,2IFHZ@201174|Actinobacteria,238S7@1762|Mycobacteriaceae	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_845450_1	1380386.JIAW01000012_gene1841	1.926e-145	478.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,237KM@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_845450_5	1121106.JQKB01000008_gene1354	2.069e-55	204.0	COG2141@1|root,COG2141@2|Bacteria,1RH44@1224|Proteobacteria,2UA83@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_845450_6	1499967.BAYZ01000007_gene5399	1.459e-47	186.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_845450_7	44056.XP_009040665.1	2.598e-43	179.0	COG5285@1|root,2S7ZW@2759|Eukaryota	2759|Eukaryota	Q	dioxygenase activity	-	GO:0008150,GO:0008152,GO:0009058,GO:0019748,GO:0044550,GO:0071704,GO:1900558,GO:1900560,GO:1900561,GO:1900563,GO:1901576	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_845450_0	1396418.BATQ01000133_gene4074	4.623e-149	489.0	COG0626@1|root,COG0626@2|Bacteria,46V6V@74201|Verrucomicrobia,2IWMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
CMS3_k127_845450_4	460265.Mnod_6596	1.745e-84	305.0	COG0454@1|root,COG0456@2|Bacteria,1R8G2@1224|Proteobacteria,2U8TP@28211|Alphaproteobacteria,1JXD6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_845450_2	1283299.AUKG01000002_gene5002	6.694e-137	453.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,4CQYP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_845450_9	234621.RER_48870	5.917e-36	157.0	COG1075@1|root,COG1075@2|Bacteria,2GJGC@201174|Actinobacteria,4G3MT@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_853233_12	591159.ACEZ01000133_gene7409	1.199e-38	151.0	COG1545@1|root,COG2050@1|root,COG1545@2|Bacteria,COG2050@2|Bacteria,2GM2A@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,MaoC_dehydrat_N,MaoC_dehydratas,OB_aCoA_assoc
CMS3_k127_853233_15	1229780.BN381_310017	4.608e-21	104.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_853233_19	1463926.JOCA01000002_gene6078	5.602e-06	56.0	COG1846@1|root,COG1846@2|Bacteria,2GM7K@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_853233_10	272630.MexAM1_META1p5207	1.111e-52	196.0	COG0500@1|root,COG2226@2|Bacteria,1PN45@1224|Proteobacteria,2U64U@28211|Alphaproteobacteria,1JQSD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM UbiE COQ5 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_853233_13	1254432.SCE1572_07125	2.576e-35	153.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2WVSN@28221|Deltaproteobacteria,2Z1YP@29|Myxococcales	28221|Deltaproteobacteria	F	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CMS3_k127_853233_17	391625.PPSIR1_03103	2.998e-10	74.0	COG0026@1|root,COG2833@1|root,COG0026@2|Bacteria,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2WVSN@28221|Deltaproteobacteria,2Z1YP@29|Myxococcales	28221|Deltaproteobacteria	F	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CMS3_k127_853233_9	1519464.HY22_11880	3.907e-53	211.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_853233_5	477228.YO5_17295	8.245e-65	230.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,1YZZV@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
CMS3_k127_853233_4	1123242.JH636434_gene3281	5.501e-77	284.0	COG1024@1|root,COG1024@2|Bacteria,2IZFF@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_853233_16	6183.Smp_162880.1	9.058e-21	109.0	KOG3873@1|root,KOG3873@2759|Eukaryota,39U5K@33154|Opisthokonta,3BGK9@33208|Metazoa,3CS5D@33213|Bilateria	33208|Metazoa	T	sphingomyelin phosphodiesterase activity	SMPD2	GO:0003674,GO:0003824,GO:0004620,GO:0004767,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005901,GO:0006629,GO:0006643,GO:0006644,GO:0006665,GO:0006672,GO:0006684,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009612,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010556,GO:0010941,GO:0010942,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019216,GO:0019222,GO:0019637,GO:0023052,GO:0030148,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0034248,GO:0034250,GO:0034641,GO:0035556,GO:0042578,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043603,GO:0043604,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044853,GO:0045121,GO:0045834,GO:0046467,GO:0046513,GO:0046889,GO:0046890,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090153,GO:0090154,GO:0097164,GO:0098589,GO:0098590,GO:0098805,GO:0098857,GO:1901564,GO:1901566,GO:1901576,GO:1905038,GO:2000303,GO:2000304	3.1.4.12	ko:K12351	ko00600,ko01100,ko04071,map00600,map01100,map04071	-	R02541	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
CMS3_k127_853233_11	72019.SARC_06571T0	2.43e-48	181.0	COG1011@1|root,COG3173@1|root,KOG1469@2759|Eukaryota,KOG3085@2759|Eukaryota,38BWX@33154|Opisthokonta	33154|Opisthokonta	I	very-long-chain-acyl-CoA dehydrogenase activity	ACAD10	GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.3.8.7	ko:K00249,ko:K11729	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,HAD_2,Hydrolase
CMS3_k127_853233_8	1205908.AKXW01000108_gene1200	2.206e-54	216.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,1RSQ1@1236|Gammaproteobacteria,1XWGA@135623|Vibrionales	135623|Vibrionales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_853233_3	1240350.AMZE01000086_gene4369	9.258e-99	335.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RQZ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	kshB	-	1.14.13.142	ko:K02613,ko:K15983	ko00360,ko00984,ko01100,ko01120,map00360,map00984,map01100,map01120	-	R09838,R09860	RC02690,RC02691	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1
CMS3_k127_853233_2	1177179.A11A3_08895	2.197e-125	421.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS3_k127_853233_14	368407.Memar_1772	6.618e-23	116.0	COG1226@1|root,arCOG01958@2157|Archaea	2157|Archaea	P	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
CMS3_k127_853233_0	745411.B3C1_11334	0.0	1220.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5K5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS3_k127_853233_6	309807.SRU_0084	5.743e-64	234.0	COG0845@1|root,COG0845@2|Bacteria,4NE7P@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS3_k127_853233_7	247633.GP2143_02604	7.06e-64	227.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,1S32P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Thij pfpi	thiJ	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS3_k127_853233_1	1089552.KI911559_gene1479	4.992e-175	565.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,2JPS4@204441|Rhodospirillales	204441|Rhodospirillales	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_853233_18	1278073.MYSTI_04829	4.436e-06	49.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria	1224|Proteobacteria	K	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_882530_13	1254432.SCE1572_04480	4.634e-81	277.0	COG1716@1|root,COG2203@1|root,COG3829@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_882530_3	1454004.AW11_03211	3.141e-161	530.0	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,2VN83@28216|Betaproteobacteria	28216|Betaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS3_k127_882530_6	1415166.NONO_c61350	6.206e-100	335.0	COG1024@1|root,COG1024@2|Bacteria,2GNZE@201174|Actinobacteria,4FUSQ@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_882530_8	485913.Krac_5151	1.645e-98	354.0	COG0654@1|root,COG0654@2|Bacteria,2G6UH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_882530_9	314230.DSM3645_16890	4.981e-98	333.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_882530_2	1121272.KB903249_gene2267	3.187e-245	782.0	28IUR@1|root,2Z8TE@2|Bacteria,2I9P5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_882530_28	469383.Cwoe_4936	0.0002776	49.0	2EE69@1|root,3380V@2|Bacteria,2GR09@201174|Actinobacteria,4CTGN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_882530_12	261292.Nit79A3_0543	4.828e-87	299.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,2WBU3@28216|Betaproteobacteria,373TA@32003|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Sulfotransferase	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CMS3_k127_882530_10	745014.OMB55_00010940	6.389e-96	323.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,1RZNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Alpha beta hydrolase	dhaA	-	3.8.1.5	ko:K01563,ko:K22318	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_882530_11	2074.JNYD01000031_gene6583	1.483e-89	331.0	COG1024@1|root,COG1024@2|Bacteria,2H25N@201174|Actinobacteria,4EBYU@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_882530_19	1120953.AUBH01000001_gene1208	1.563e-33	147.0	COG2755@1|root,COG2755@2|Bacteria,1R43M@1224|Proteobacteria,1RRTK@1236|Gammaproteobacteria,465MH@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_882530_7	525904.Tter_0396	1.065e-98	360.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_882530_4	94624.Bpet2716	2.674e-156	508.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,3T3DF@506|Alcaligenaceae	28216|Betaproteobacteria	NT	DinB superfamily	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS3_k127_882530_23	768671.ThimaDRAFT_1465	1.151e-14	83.0	COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria,1X10E@135613|Chromatiales	135613|Chromatiales	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS3_k127_882530_0	1242864.D187_002077	0.0	1476.0	COG0514@1|root,COG0550@1|root,COG0514@2|Bacteria,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42NQG@68525|delta/epsilon subdivisions,2WJXC@28221|Deltaproteobacteria,2YU8A@29|Myxococcales	28221|Deltaproteobacteria	L	ATP-dependent DNA helicase RecQ	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DEAD,HRDC,Helicase_C,RecQ_Zn_bind,Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom
CMS3_k127_882530_20	502025.Hoch_6130	1.248e-29	138.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF772,RibD_C,dCMP_cyt_deam_1
CMS3_k127_882530_27	330779.Saci_0387	1.828e-06	51.0	arCOG06207@1|root,arCOG06207@2157|Archaea	2157|Archaea	S	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
CMS3_k127_882530_17	234267.Acid_2119	4.608e-47	185.0	COG0784@1|root,COG3292@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,3Y9A4@57723|Acidobacteria	57723|Acidobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS3_k127_882530_22	575540.Isop_3231	2.402e-15	89.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
CMS3_k127_882530_26	2880.D7FTB3	1.907e-08	68.0	COG0457@1|root,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	ko:K10407	ko05132,map05132	-	-	-	ko00000,ko00001,ko03019,ko04812	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_16,TPR_4,TPR_7,TPR_8
CMS3_k127_882530_14	1487953.JMKF01000053_gene1809	2.361e-61	232.0	COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,1HA80@1150|Oscillatoriales	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS3_k127_882530_25	1408473.JHXO01000009_gene3263	1.225e-08	65.0	2FFU4@1|root,347R8@2|Bacteria,4P5R2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_882530_15	593907.Celgi_3026	1.921e-56	222.0	COG0572@1|root,COG0572@2|Bacteria,2GMCP@201174|Actinobacteria	201174|Actinobacteria	F	PFAM AIG2 family protein	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS3_k127_882530_18	1144275.COCOR_04542	1.255e-37	157.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42SWK@68525|delta/epsilon subdivisions,2WPU0@28221|Deltaproteobacteria,2YUSY@29|Myxococcales	28221|Deltaproteobacteria	H	tRNA nucleotidyltransferase domain 2 putative	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
CMS3_k127_882530_1	502025.Hoch_1793	3.225e-307	989.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YUB7@29|Myxococcales	28221|Deltaproteobacteria	KL	Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
CMS3_k127_882530_16	1313172.YM304_38750	1.896e-50	191.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_882530_21	391735.Veis_4954	4.373e-25	124.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Polysacc_synt_3,Polysacc_synt_C
CMS3_k127_882530_5	644966.Tmar_1963	2.874e-137	466.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,3WCYU@538999|Clostridiales incertae sedis	186801|Clostridia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_882530_24	314271.RB2654_15951	1.837e-10	65.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	3-hydroxyacyl-coa dehydrogenase	bhbD	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_912095_7	234267.Acid_3825	4.83e-195	620.0	COG0531@1|root,COG0531@2|Bacteria,3Y6J9@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	-
CMS3_k127_912095_46	1242864.D187_001940	9.41e-25	121.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS3_k127_912095_34	1307437.J139_00240	5.001e-52	205.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,2PZFP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS3_k127_912095_48	67267.JNXT01000023_gene4419	2.319e-23	112.0	COG1670@1|root,COG1670@2|Bacteria,2IBCX@201174|Actinobacteria	201174|Actinobacteria	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
CMS3_k127_912095_17	298655.KI912267_gene6924	8.501e-114	411.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA5	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_912095_64	1183438.GKIL_0463	1.148e-05	58.0	COG5617@1|root,COG5617@2|Bacteria,1GBZS@1117|Cyanobacteria	1117|Cyanobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_912095_39	694430.Natoc_2251	8.519e-43	181.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_912095_22	469383.Cwoe_3478	4.466e-95	352.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_912095_43	1232437.KL662025_gene956	1.139e-35	151.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WN8R@28221|Deltaproteobacteria,2MPGW@213118|Desulfobacterales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
CMS3_k127_912095_51	134676.ACPL_8369	5.874e-22	104.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4DD37@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_912095_15	1454004.AW11_00555	3.374e-122	419.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,1KPQ8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	DNA recombination protein RmuC	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS3_k127_912095_28	448385.sce7002	2.967e-75	267.0	COG3173@1|root,COG3173@2|Bacteria,1P7JU@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_912095_49	37919.EP51_14665	5.834e-23	110.0	COG0500@1|root,COG2226@2|Bacteria,2INQ9@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_912095_12	1219035.NT2_08_00730	1.503e-152	495.0	COG2124@1|root,COG2124@2|Bacteria,1R4B1@1224|Proteobacteria,2U416@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_912095_58	37919.EP51_17965	1.986e-13	83.0	COG1141@1|root,COG1141@2|Bacteria,2GS47@201174|Actinobacteria,4G3V5@85025|Nocardiaceae	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13,Fer4_15
CMS3_k127_912095_59	290397.Adeh_2735	6.176e-12	77.0	COG3267@1|root,COG3267@2|Bacteria,1REY9@1224|Proteobacteria,42RJB@68525|delta/epsilon subdivisions,2WN99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
CMS3_k127_912095_66	67275.JOAP01000022_gene1727	0.0005903	52.0	29S1K@1|root,30D60@2|Bacteria,2IQ0K@201174|Actinobacteria	67275.JOAP01000022_gene1727|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_912095_55	1033802.SSPSH_000666	1.338e-16	93.0	2A4CF@1|root,30SY3@2|Bacteria,1RFXP@1224|Proteobacteria,1SP3W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_912095_52	391625.PPSIR1_10645	1.187e-20	103.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,2Z1R6@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_912095_44	404589.Anae109_1886	1.959e-34	136.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,2YVCZ@29|Myxococcales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_912095_42	227377.CBU_1323	1.575e-39	151.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1JEHD@118969|Legionellales	118969|Legionellales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS3_k127_912095_56	1294142.CINTURNW_1372	1.171e-14	84.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,36MNG@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS3_k127_912095_37	1158318.ATXC01000001_gene271	1.917e-50	189.0	COG0290@1|root,COG0290@2|Bacteria,2G432@200783|Aquificae	200783|Aquificae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS3_k127_912095_9	1158756.AQXQ01000010_gene2147	1.116e-170	565.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS3_k127_912095_1	269799.Gmet_1215	0.0	1077.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43SUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_912095_5	1125863.JAFN01000001_gene1801	2.085e-210	666.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
CMS3_k127_912095_6	1232410.KI421424_gene1679	3.722e-209	669.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,43RY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
CMS3_k127_912095_61	314231.FP2506_13259	9.086e-09	68.0	COG0664@1|root,COG0664@2|Bacteria,1N4S8@1224|Proteobacteria,2UCQ3@28211|Alphaproteobacteria,2PK6I@255475|Aurantimonadaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_912095_40	404589.Anae109_0615	9.47e-42	173.0	COG0745@1|root,COG0745@2|Bacteria,1P9P4@1224|Proteobacteria,43354@68525|delta/epsilon subdivisions,2WY4R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
CMS3_k127_912095_27	290397.Adeh_0571	1.159e-76	280.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1P2AZ@1224|Proteobacteria,4312R@68525|delta/epsilon subdivisions,2WWR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS3_k127_912095_16	269799.Gmet_2296	3.458e-118	399.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,43T2G@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_912095_36	1123320.KB889721_gene7475	4.33e-51	200.0	COG5285@1|root,COG5285@2|Bacteria,2IC8K@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_912095_11	1121904.ARBP01000010_gene2316	3.312e-160	542.0	COG1167@1|root,COG1167@2|Bacteria	2|Bacteria	K	transaminase activity	aspT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
CMS3_k127_912095_60	1137281.D778_01967	4.705e-10	71.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1HY3M@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
CMS3_k127_912095_14	314230.DSM3645_11851	2.91e-147	489.0	COG0471@1|root,COG0471@2|Bacteria,2IWY9@203682|Planctomycetes	203682|Planctomycetes	P	COG0471 Di- and tricarboxylate	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS3_k127_912095_26	1144275.COCOR_04197	4.218e-82	301.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,42QBK@68525|delta/epsilon subdivisions,2WITZ@28221|Deltaproteobacteria,2YW16@29|Myxococcales	28221|Deltaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_912095_19	1297742.A176_04526	7.145e-112	383.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42N5A@68525|delta/epsilon subdivisions,2WKKI@28221|Deltaproteobacteria,2YUUT@29|Myxococcales	28221|Deltaproteobacteria	O	AAA domain (Cdc48 subfamily)	clpB1	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS3_k127_912095_8	243231.GSU1690	8.511e-178	569.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43U14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS3_k127_912095_18	1411123.JQNH01000001_gene3251	2.767e-113	382.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_912095_32	1278073.MYSTI_07318	3.921e-62	223.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria,2YUYK@29|Myxococcales	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
CMS3_k127_912095_21	1150626.PHAMO_210316	2.76e-106	355.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,2JP84@204441|Rhodospirillales	204441|Rhodospirillales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_912095_2	319795.Dgeo_1320	0.0	1041.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1WIBM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	bhbA	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS3_k127_912095_0	1380390.JIAT01000013_gene276	0.0	1299.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4CS56@84995|Rubrobacteria	84995|Rubrobacteria	EI	ArgK protein	-	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS3_k127_912095_47	1125863.JAFN01000001_gene169	2.936e-24	108.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcription regulator MerR DNA binding	-	-	-	ko:K21902	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
CMS3_k127_912095_4	290397.Adeh_1646	1.199e-216	684.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,42N6D@68525|delta/epsilon subdivisions,2X5IJ@28221|Deltaproteobacteria,2YWT3@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS3_k127_912095_24	1048834.TC41_2173	3.416e-88	314.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,2795U@186823|Alicyclobacillaceae	91061|Bacilli	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_912095_33	1125863.JAFN01000001_gene573	4.352e-61	228.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS3_k127_912095_41	411467.BACCAP_04652	6.275e-41	174.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,2691S@186813|unclassified Clostridiales	186801|Clostridia	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS3_k127_912095_25	234267.Acid_0599	3.93e-85	314.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS3_k127_912095_23	269799.Gmet_0872	1.54e-92	317.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,43S8G@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-2	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,Molybdopterin,Molydop_binding
CMS3_k127_912095_29	269799.Gmet_2779	2.258e-67	247.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
CMS3_k127_912095_62	999141.GME_07306	4.548e-07	59.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1XMIW@135619|Oceanospirillales	135619|Oceanospirillales	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
CMS3_k127_912095_13	338963.Pcar_1006	2.104e-151	498.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,43U9Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM aspartate glutamate uridylate kinase	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS3_k127_912095_45	756272.Plabr_2835	3.471e-26	117.0	COG0802@1|root,COG0802@2|Bacteria,2J06N@203682|Planctomycetes	203682|Planctomycetes	S	ATPase or kinase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS3_k127_912095_20	1232410.KI421415_gene3033	2.395e-107	371.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,43T92@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS3_k127_912095_63	585503.HMPREF7545_0752	9.684e-07	56.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4H55G@909932|Negativicutes	909932|Negativicutes	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_912095_50	96561.Dole_0776	1.85e-22	106.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2MJ54@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
CMS3_k127_912095_10	1123371.ATXH01000013_gene1532	1.92e-165	546.0	COG1109@1|root,COG1109@2|Bacteria,2GGQT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_912095_53	589865.DaAHT2_0444	2.636e-20	102.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MIQJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
CMS3_k127_912095_31	1125863.JAFN01000001_gene2161	2.981e-63	230.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
CMS3_k127_912095_30	483219.LILAB_29895	4.933e-64	233.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS3_k127_912095_3	1232410.KI421415_gene3040	8.616e-242	763.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,43S6Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	FtsH Extracellular	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS3_k127_912095_38	1121405.dsmv_3256	1.009e-43	172.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2MHPA@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS3_k127_912095_57	1120956.JHZK01000001_gene3303	3.501e-14	85.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_912095_54	1120948.KB903229_gene5298	1.091e-16	90.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZX5@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_931560_0	1122611.KB903997_gene7715	1.779e-122	404.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4EHHR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_931560_1	479434.Sthe_2905	4.881e-117	395.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,27XFT@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_931560_6	314231.FP2506_16064	1.473e-53	196.0	COG2343@1|root,COG2343@2|Bacteria,1RJ3M@1224|Proteobacteria,2U98N@28211|Alphaproteobacteria,2PM3K@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS3_k127_931560_3	1282876.BAOK01000001_gene1456	2.255e-89	310.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha beta hydrolase	-	-	2.7.10.2,3.3.2.9	ko:K01253,ko:K08253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS3_k127_931560_2	485913.Krac_2932	1.125e-107	358.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	qor2	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_931560_5	402881.Plav_1789	3.15e-56	218.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2U4E2@28211|Alphaproteobacteria,1JP8W@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS3_k127_931560_4	1415756.JQMY01000005_gene34	4.718e-58	220.0	28MWZ@1|root,2ZB46@2|Bacteria,1R7K6@1224|Proteobacteria,2U4ZP@28211|Alphaproteobacteria,2PFK3@252301|Oceanicola	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_931560_7	1142394.PSMK_30420	2.006e-33	137.0	2E2CP@1|root,32XHN@2|Bacteria,2J0IA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_973112_18	1227457.C451_12839	3.854e-47	192.0	arCOG11398@1|root,arCOG11398@2157|Archaea,2XXI5@28890|Euryarchaeota,23VIQ@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
CMS3_k127_973112_11	639030.JHVA01000001_gene2812	1.863e-73	259.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
CMS3_k127_973112_2	118161.KB235922_gene1210	9.166e-213	673.0	COG2072@1|root,COG2072@2|Bacteria,1G8W3@1117|Cyanobacteria	1117|Cyanobacteria	C	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
CMS3_k127_973112_3	1282876.BAOK01000001_gene1319	3.064e-132	436.0	COG4638@1|root,COG4638@2|Bacteria,1RBGZ@1224|Proteobacteria,2U82S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_973112_29	1282876.BAOK01000001_gene1320	3.461e-09	66.0	COG1309@1|root,COG1309@2|Bacteria,1NJ7X@1224|Proteobacteria,2UNRW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_973112_6	266264.Rmet_5553	1.741e-112	378.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2W9PC@28216|Betaproteobacteria,1KC8F@119060|Burkholderiaceae	28216|Betaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_973112_5	596151.DesfrDRAFT_4043	1.516e-122	407.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2M7YC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS3_k127_973112_27	1122609.AUGT01000003_gene2457	7.03e-16	83.0	COG1545@1|root,COG1545@2|Bacteria,2HQJV@201174|Actinobacteria,4DW22@85009|Propionibacteriales	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_973112_13	1122603.ATVI01000005_gene3527	2.533e-70	249.0	COG0625@1|root,COG0625@2|Bacteria,1P71B@1224|Proteobacteria,1S29M@1236|Gammaproteobacteria,1X6X1@135614|Xanthomonadales	135614|Xanthomonadales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
CMS3_k127_973112_10	1123023.JIAI01000001_gene6175	5.558e-76	267.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E188@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
CMS3_k127_973112_19	749927.AMED_7648	8.532e-45	168.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4E3G4@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS3_k127_973112_0	525368.HMPREF0591_3256	1.171e-269	851.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,232Y5@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_973112_12	1160137.KB907308_gene6437	2.03e-70	256.0	COG5285@1|root,COG5285@2|Bacteria,2IC8K@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_973112_14	1282876.BAOK01000001_gene3458	2.029e-66	243.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TRHJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_973112_16	1282876.BAOK01000001_gene1826	4.248e-58	208.0	COG1309@1|root,COG1309@2|Bacteria,1MY6Y@1224|Proteobacteria,2UKSE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_973112_1	1313172.YM304_03730	2.225e-224	704.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_973112_26	1282876.BAOK01000001_gene1821	7.831e-19	91.0	2DNQ5@1|root,32YJ0@2|Bacteria,1NAFP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_973112_9	1282876.BAOK01000001_gene2846	3.844e-94	319.0	COG0300@1|root,COG0300@2|Bacteria,1R409@1224|Proteobacteria,2TRST@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_973112_8	926560.KE387023_gene2192	1.226e-96	351.0	COG2124@1|root,COG2124@2|Bacteria,1WKWS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_973112_7	525897.Dbac_2942	1.761e-105	379.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_973112_17	1123261.AXDW01000007_gene2259	2.077e-54	220.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSI4@1236|Gammaproteobacteria,1X3SM@135614|Xanthomonadales	135614|Xanthomonadales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_973112_20	243233.MCA3098	2.88e-32	141.0	29WVG@1|root,30IH4@2|Bacteria,1PDEB@1224|Proteobacteria,1SXUG@1236|Gammaproteobacteria,1XGR2@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_973112_21	1123261.AXDW01000007_gene2261	2.156e-26	113.0	COG0226@1|root,COG0226@2|Bacteria,1N3EC@1224|Proteobacteria,1SF5A@1236|Gammaproteobacteria,1X8CE@135614|Xanthomonadales	135614|Xanthomonadales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_973112_22	1403819.BATR01000112_gene3746	7.735e-26	123.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	ysfE	-	2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5	ko:K00941,ko:K01724,ko:K01759,ko:K07032,ko:K08234	ko00620,ko00730,ko00790,ko01100,map00620,map00730,map00790,map01100	M00127	R02530,R03471,R04509,R04734	RC00002,RC00004,RC00017,RC00740,RC01208	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
CMS3_k127_973112_24	1536772.R70723_21840	9.511e-21	107.0	COG1595@1|root,COG1595@2|Bacteria,1V70Y@1239|Firmicutes,4HINM@91061|Bacilli,26T02@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoD3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF1835,Sigma70_r2,Sigma70_r4_2
CMS3_k127_973112_15	864069.MicloDRAFT_00024650	1.123e-64	236.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,2UQ4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
CMS3_k127_973112_4	378806.STAUR_4537	4.002e-129	427.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P6D@68525|delta/epsilon subdivisions,2WM1P@28221|Deltaproteobacteria,2YUD4@29|Myxococcales	28221|Deltaproteobacteria	T	DNA-binding response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_973112_25	886293.Sinac_5019	1.417e-20	97.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_973112_23	247633.GP2143_10757	7.286e-25	109.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,1SB02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS3_k127_973112_28	381666.H16_B2470	5.611e-11	63.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2VIJB@28216|Betaproteobacteria,1K69D@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_976829_21	1121267.JHZL01000002_gene1041	1.045e-12	68.0	2EIKW@1|root,33CC6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_976829_22	591158.SSMG_05501	2.966e-11	64.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_976829_7	883.DvMF_1356	5.069e-119	406.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2M81M@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS3_k127_976829_20	266117.Rxyl_1321	6.78e-24	113.0	COG0212@1|root,COG0212@2|Bacteria	2|Bacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
CMS3_k127_976829_25	240015.ACP_1832	0.0005751	51.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS3_k127_976829_3	1303518.CCALI_02688	4.131e-197	628.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
CMS3_k127_976829_0	671143.DAMO_0867	0.0	1752.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS3_k127_976829_18	572478.Vdis_1498	7.712e-40	159.0	COG0584@1|root,arCOG00701@2157|Archaea,2XS13@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_976829_2	644966.Tmar_1638	3.612e-206	664.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS3_k127_976829_10	316067.Geob_3595	2.681e-93	321.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,43TJM@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS3_k127_976829_4	382464.ABSI01000011_gene3022	6.193e-135	475.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia,2ITZ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	SMC proteins Flexible Hinge Domain	-	-	-	-	-	-	-	-	-	-	-	-	SMC_N,SMC_hinge
CMS3_k127_976829_5	526227.Mesil_2505	5.122e-132	466.0	COG1132@1|root,COG1132@2|Bacteria,1WIMR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS3_k127_976829_6	1089548.KI783301_gene1959	6.464e-120	421.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3WDY1@539002|Bacillales incertae sedis	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS3_k127_976829_16	63737.Npun_R3473	8.634e-49	184.0	COG1216@1|root,COG1216@2|Bacteria,1G0X3@1117|Cyanobacteria,1HK6N@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
CMS3_k127_976829_8	522306.CAP2UW1_2459	2.519e-104	353.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1KPVW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_976829_9	1122217.KB899568_gene809	9.814e-103	373.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS3_k127_976829_14	247490.KSU1_D0287	6.968e-52	211.0	COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_976829_1	316067.Geob_2145	2.52e-246	780.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,43SZI@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS3_k127_976829_15	1454004.AW11_01453	5.685e-49	187.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,1KPYB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS3_k127_976829_19	663278.Ethha_2119	1.6e-24	113.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
CMS3_k127_976829_12	1304880.JAGB01000001_gene692	1.308e-53	212.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS3_k127_976829_11	861299.J421_3478	7.511e-58	227.0	COG2870@1|root,COG2870@2|Bacteria,1ZT0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
CMS3_k127_976829_13	243231.GSU2256	7.086e-53	212.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_976829_17	903818.KI912269_gene363	1.772e-48	199.0	COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria	57723|Acidobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_976829_24	82996.sch_02555	7.845e-08	64.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,4024X@613|Serratia	1236|Gammaproteobacteria	S	Lipopolysaccharide ABC transporter permease	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
CMS3_k127_976829_23	861299.J421_3869	1.534e-09	67.0	COG3642@1|root,COG3642@2|Bacteria,1ZTTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
CMS3_k127_999689_2	1120971.AUCA01000008_gene1890	1.085e-15	88.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,4H9T5@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	ywqM	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_999689_1	1123024.AUII01000033_gene1401	1.3e-80	287.0	COG0596@1|root,COG0596@2|Bacteria,2IAKH@201174|Actinobacteria,4E9MU@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_999689_0	1168065.DOK_09474	2.291e-110	361.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,1S1Y6@1236|Gammaproteobacteria,1J5HR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
## 4815 queries scanned
## Total time (seconds): 268.3946359157562
## Rate: 17.94 q/s